Amino acid dipepetide frequency for Blautia obeum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.015AlaAla: 7.015 ± 0.126	1.124AlaCys: 1.124 ± 0.037	4.705AlaAsp: 4.705 ± 0.068	5.692AlaGlu: 5.692 ± 0.087	2.934AlaPhe: 2.934 ± 0.064	5.953AlaGly: 5.953 ± 0.09	1.102AlaHis: 1.102 ± 0.034	4.867AlaIle: 4.867 ± 0.078	4.61AlaLys: 4.61 ± 0.071	6.506AlaLeu: 6.506 ± 0.079	2.403AlaMet: 2.403 ± 0.054	2.438AlaAsn: 2.438 ± 0.06	1.975AlaPro: 1.975 ± 0.051	2.324AlaGln: 2.324 ± 0.058	2.871AlaArg: 2.871 ± 0.057	3.925AlaSer: 3.925 ± 0.079	3.326AlaThr: 3.326 ± 0.064	6.355AlaVal: 6.355 ± 0.103	0.631AlaTrp: 0.631 ± 0.027	2.721AlaTyr: 2.721 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.086CysAla: 1.086 ± 0.035	0.319CysCys: 0.319 ± 0.019	0.853CysAsp: 0.853 ± 0.031	0.929CysGlu: 0.929 ± 0.034	0.623CysPhe: 0.623 ± 0.024	1.575CysGly: 1.575 ± 0.048	0.332CysHis: 0.332 ± 0.019	1.1CysIle: 1.1 ± 0.038	0.868CysLys: 0.868 ± 0.034	1.203CysLeu: 1.203 ± 0.035	0.499CysMet: 0.499 ± 0.024	0.625CysAsn: 0.625 ± 0.024	0.639CysPro: 0.639 ± 0.03	0.514CysGln: 0.514 ± 0.025	0.719CysArg: 0.719 ± 0.031	0.947CysSer: 0.947 ± 0.027	0.81CysThr: 0.81 ± 0.032	1.027CysVal: 1.027 ± 0.037	0.137CysTrp: 0.137 ± 0.011	0.568CysTyr: 0.568 ± 0.027	0.0CysXaa: 0.0 ± 0.0
Asp	4.238AspAla: 4.238 ± 0.086	0.806AspCys: 0.806 ± 0.036	3.106AspAsp: 3.106 ± 0.077	4.739AspGlu: 4.739 ± 0.076	2.527AspPhe: 2.527 ± 0.056	4.482AspGly: 4.482 ± 0.089	1.009AspHis: 1.009 ± 0.035	4.563AspIle: 4.563 ± 0.062	3.655AspLys: 3.655 ± 0.069	4.655AspLeu: 4.655 ± 0.07	1.953AspMet: 1.953 ± 0.042	2.271AspAsn: 2.271 ± 0.053	1.794AspPro: 1.794 ± 0.047	1.602AspGln: 1.602 ± 0.038	2.347AspArg: 2.347 ± 0.054	3.294AspSer: 3.294 ± 0.062	3.354AspThr: 3.354 ± 0.072	3.824AspVal: 3.824 ± 0.068	0.585AspTrp: 0.585 ± 0.031	2.729AspTyr: 2.729 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	5.511GluAla: 5.511 ± 0.081	0.86GluCys: 0.86 ± 0.03	4.462GluAsp: 4.462 ± 0.076	7.352GluGlu: 7.352 ± 0.101	2.768GluPhe: 2.768 ± 0.054	4.38GluGly: 4.38 ± 0.063	1.422GluHis: 1.422 ± 0.037	5.922GluIle: 5.922 ± 0.091	7.12GluLys: 7.12 ± 0.107	6.87GluLeu: 6.87 ± 0.099	2.575GluMet: 2.575 ± 0.054	4.291GluAsn: 4.291 ± 0.07	1.791GluPro: 1.791 ± 0.05	2.948GluGln: 2.948 ± 0.055	3.179GluArg: 3.179 ± 0.07	3.337GluSer: 3.337 ± 0.076	4.121GluThr: 4.121 ± 0.082	4.517GluVal: 4.517 ± 0.076	0.673GluTrp: 0.673 ± 0.026	3.155GluTyr: 3.155 ± 0.068	0.0GluXaa: 0.0 ± 0.0
Phe	2.796PheAla: 2.796 ± 0.055	0.797PheCys: 0.797 ± 0.028	2.43PheAsp: 2.43 ± 0.053	2.534PheGlu: 2.534 ± 0.055	1.854PhePhe: 1.854 ± 0.053	3.002PheGly: 3.002 ± 0.065	0.878PheHis: 0.878 ± 0.025	2.681PheIle: 2.681 ± 0.056	1.933PheLys: 1.933 ± 0.047	3.892PheLeu: 3.892 ± 0.074	1.27PheMet: 1.27 ± 0.036	1.49PheAsn: 1.49 ± 0.04	1.35PhePro: 1.35 ± 0.039	1.442PheGln: 1.442 ± 0.034	1.782PheArg: 1.782 ± 0.047	2.772PheSer: 2.772 ± 0.056	2.308PheThr: 2.308 ± 0.055	2.791PheVal: 2.791 ± 0.062	0.455PheTrp: 0.455 ± 0.027	1.74PheTyr: 1.74 ± 0.043	0.0PheXaa: 0.0 ± 0.0
Gly	4.788GlyAla: 4.788 ± 0.092	1.319GlyCys: 1.319 ± 0.047	3.469GlyAsp: 3.469 ± 0.075	4.652GlyGlu: 4.652 ± 0.068	3.082GlyPhe: 3.082 ± 0.064	4.66GlyGly: 4.66 ± 0.105	1.289GlyHis: 1.289 ± 0.036	6.324GlyIle: 6.324 ± 0.082	5.641GlyLys: 5.641 ± 0.072	5.583GlyLeu: 5.583 ± 0.077	2.601GlyMet: 2.601 ± 0.053	3.198GlyAsn: 3.198 ± 0.063	1.25GlyPro: 1.25 ± 0.038	2.127GlyGln: 2.127 ± 0.05	2.986GlyArg: 2.986 ± 0.062	4.112GlySer: 4.112 ± 0.069	4.327GlyThr: 4.327 ± 0.07	4.854GlyVal: 4.854 ± 0.084	0.697GlyTrp: 0.697 ± 0.029	3.283GlyTyr: 3.283 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	1.202HisAla: 1.202 ± 0.041	0.315HisCys: 0.315 ± 0.018	0.92HisAsp: 0.92 ± 0.034	1.163HisGlu: 1.163 ± 0.035	0.846HisPhe: 0.846 ± 0.029	1.291HisGly: 1.291 ± 0.041	0.425HisHis: 0.425 ± 0.027	1.382HisIle: 1.382 ± 0.035	1.104HisLys: 1.104 ± 0.038	1.534HisLeu: 1.534 ± 0.043	0.592HisMet: 0.592 ± 0.023	0.736HisAsn: 0.736 ± 0.031	0.934HisPro: 0.934 ± 0.034	0.603HisGln: 0.603 ± 0.024	0.847HisArg: 0.847 ± 0.028	0.985HisSer: 0.985 ± 0.03	1.012HisThr: 1.012 ± 0.033	1.171HisVal: 1.171 ± 0.037	0.168HisTrp: 0.168 ± 0.012	0.744HisTyr: 0.744 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.454IleAla: 5.454 ± 0.082	1.437IleCys: 1.437 ± 0.043	3.919IleAsp: 3.919 ± 0.071	4.601IleGlu: 4.601 ± 0.083	2.995IlePhe: 2.995 ± 0.051	4.925IleGly: 4.925 ± 0.078	1.461IleHis: 1.461 ± 0.041	4.93IleIle: 4.93 ± 0.081	4.0IleLys: 4.0 ± 0.061	7.381IleLeu: 7.381 ± 0.116	2.055IleMet: 2.055 ± 0.046	2.752IleAsn: 2.752 ± 0.054	3.229IlePro: 3.229 ± 0.064	2.646IleGln: 2.646 ± 0.057	3.716IleArg: 3.716 ± 0.071	4.896IleSer: 4.896 ± 0.081	4.166IleThr: 4.166 ± 0.073	4.814IleVal: 4.814 ± 0.068	0.686IleTrp: 0.686 ± 0.029	2.831IleTyr: 2.831 ± 0.055	0.0IleXaa: 0.0 ± 0.0
Lys	5.115LysAla: 5.115 ± 0.08	0.823LysCys: 0.823 ± 0.031	4.203LysAsp: 4.203 ± 0.07	6.974LysGlu: 6.974 ± 0.098	2.047LysPhe: 2.047 ± 0.053	4.21LysGly: 4.21 ± 0.072	1.04LysHis: 1.04 ± 0.035	5.156LysIle: 5.156 ± 0.083	6.831LysLys: 6.831 ± 0.102	5.495LysLeu: 5.495 ± 0.078	2.46LysMet: 2.46 ± 0.054	3.823LysAsn: 3.823 ± 0.071	1.92LysPro: 1.92 ± 0.047	2.355LysGln: 2.355 ± 0.048	2.979LysArg: 2.979 ± 0.059	3.29LysSer: 3.29 ± 0.052	3.818LysThr: 3.818 ± 0.061	4.455LysVal: 4.455 ± 0.079	0.638LysTrp: 0.638 ± 0.023	3.027LysTyr: 3.027 ± 0.06	0.0LysXaa: 0.0 ± 0.0
Leu	6.558LeuAla: 6.558 ± 0.087	1.515LeuCys: 1.515 ± 0.041	5.081LeuAsp: 5.081 ± 0.072	6.315LeuGlu: 6.315 ± 0.098	3.55LeuPhe: 3.55 ± 0.078	5.831LeuGly: 5.831 ± 0.082	1.668LeuHis: 1.668 ± 0.041	5.933LeuIle: 5.933 ± 0.096	6.476LeuLys: 6.476 ± 0.094	8.506LeuLeu: 8.506 ± 0.116	2.614LeuMet: 2.614 ± 0.053	3.863LeuAsn: 3.863 ± 0.066	3.447LeuPro: 3.447 ± 0.059	2.958LeuGln: 2.958 ± 0.055	3.624LeuArg: 3.624 ± 0.07	5.863LeuSer: 5.863 ± 0.09	5.14LeuThr: 5.14 ± 0.07	5.409LeuVal: 5.409 ± 0.076	0.725LeuTrp: 0.725 ± 0.032	3.23LeuTyr: 3.23 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.549MetAla: 2.549 ± 0.06	0.389MetCys: 0.389 ± 0.02	2.006MetAsp: 2.006 ± 0.046	2.662MetGlu: 2.662 ± 0.066	1.047MetPhe: 1.047 ± 0.031	2.093MetGly: 2.093 ± 0.051	0.469MetHis: 0.469 ± 0.021	2.309MetIle: 2.309 ± 0.054	2.7MetLys: 2.7 ± 0.049	2.718MetLeu: 2.718 ± 0.048	0.978MetMet: 0.978 ± 0.041	1.682MetAsn: 1.682 ± 0.041	1.103MetPro: 1.103 ± 0.037	1.152MetGln: 1.152 ± 0.037	1.21MetArg: 1.21 ± 0.041	1.863MetSer: 1.863 ± 0.049	1.855MetThr: 1.855 ± 0.047	1.877MetVal: 1.877 ± 0.049	0.222MetTrp: 0.222 ± 0.015	0.932MetTyr: 0.932 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	3.104AsnAla: 3.104 ± 0.062	0.665AsnCys: 0.665 ± 0.026	2.196AsnAsp: 2.196 ± 0.042	2.835AsnGlu: 2.835 ± 0.06	1.632AsnPhe: 1.632 ± 0.044	3.61AsnGly: 3.61 ± 0.074	0.816AsnHis: 0.816 ± 0.033	3.397AsnIle: 3.397 ± 0.061	2.647AsnLys: 2.647 ± 0.062	3.883AsnLeu: 3.883 ± 0.058	1.458AsnMet: 1.458 ± 0.043	1.76AsnAsn: 1.76 ± 0.049	2.028AsnPro: 2.028 ± 0.046	1.469AsnGln: 1.469 ± 0.047	2.027AsnArg: 2.027 ± 0.05	2.318AsnSer: 2.318 ± 0.05	2.534AsnThr: 2.534 ± 0.06	2.724AsnVal: 2.724 ± 0.054	0.449AsnTrp: 0.449 ± 0.024	1.902AsnTyr: 1.902 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	2.314ProAla: 2.314 ± 0.055	0.449ProCys: 0.449 ± 0.021	2.37ProAsp: 2.37 ± 0.046	3.44ProGlu: 3.44 ± 0.07	1.49ProPhe: 1.49 ± 0.037	2.329ProGly: 2.329 ± 0.052	0.58ProHis: 0.58 ± 0.025	1.921ProIle: 1.921 ± 0.046	1.912ProLys: 1.912 ± 0.047	2.68ProLeu: 2.68 ± 0.057	0.877ProMet: 0.877 ± 0.03	1.152ProAsn: 1.152 ± 0.029	0.645ProPro: 0.645 ± 0.027	1.034ProGln: 1.034 ± 0.04	0.999ProArg: 0.999 ± 0.034	1.784ProSer: 1.784 ± 0.041	1.696ProThr: 1.696 ± 0.05	3.127ProVal: 3.127 ± 0.052	0.327ProTrp: 0.327 ± 0.017	1.438ProTyr: 1.438 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	2.509GlnAla: 2.509 ± 0.053	0.382GlnCys: 0.382 ± 0.02	1.718GlnAsp: 1.718 ± 0.042	3.033GlnGlu: 3.033 ± 0.068	1.128GlnPhe: 1.128 ± 0.032	2.015GlnGly: 2.015 ± 0.045	0.502GlnHis: 0.502 ± 0.021	2.711GlnIle: 2.711 ± 0.053	3.253GlnLys: 3.253 ± 0.065	2.74GlnLeu: 2.74 ± 0.054	1.226GlnMet: 1.226 ± 0.033	1.866GlnAsn: 1.866 ± 0.038	0.969GlnPro: 0.969 ± 0.029	1.309GlnGln: 1.309 ± 0.046	1.316GlnArg: 1.316 ± 0.041	1.595GlnSer: 1.595 ± 0.042	1.826GlnThr: 1.826 ± 0.045	2.04GlnVal: 2.04 ± 0.046	0.317GlnTrp: 0.317 ± 0.02	1.369GlnTyr: 1.369 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.596ArgAla: 2.596 ± 0.055	0.6ArgCys: 0.6 ± 0.025	2.178ArgAsp: 2.178 ± 0.054	3.783ArgGlu: 3.783 ± 0.078	1.703ArgPhe: 1.703 ± 0.053	2.362ArgGly: 2.362 ± 0.058	0.815ArgHis: 0.815 ± 0.03	3.437ArgIle: 3.437 ± 0.064	3.814ArgLys: 3.814 ± 0.065	3.614ArgLeu: 3.614 ± 0.075	1.488ArgMet: 1.488 ± 0.039	2.114ArgAsn: 2.114 ± 0.044	1.329ArgPro: 1.329 ± 0.044	1.661ArgGln: 1.661 ± 0.042	2.239ArgArg: 2.239 ± 0.055	2.105ArgSer: 2.105 ± 0.047	2.301ArgThr: 2.301 ± 0.05	2.6ArgVal: 2.6 ± 0.058	0.381ArgTrp: 0.381 ± 0.021	1.846ArgTyr: 1.846 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	4.162SerAla: 4.162 ± 0.077	0.836SerCys: 0.836 ± 0.031	3.437SerAsp: 3.437 ± 0.076	3.934SerGlu: 3.934 ± 0.067	2.641SerPhe: 2.641 ± 0.06	4.901SerGly: 4.901 ± 0.072	0.974SerHis: 0.974 ± 0.029	3.859SerIle: 3.859 ± 0.071	3.281SerLys: 3.281 ± 0.064	4.903SerLeu: 4.903 ± 0.08	1.821SerMet: 1.821 ± 0.044	2.244SerAsn: 2.244 ± 0.045	1.67SerPro: 1.67 ± 0.044	1.848SerGln: 1.848 ± 0.05	2.763SerArg: 2.763 ± 0.061	3.724SerSer: 3.724 ± 0.091	2.832SerThr: 2.832 ± 0.06	4.375SerVal: 4.375 ± 0.076	0.618SerTrp: 0.618 ± 0.026	2.438SerTyr: 2.438 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	4.409ThrAla: 4.409 ± 0.078	0.72ThrCys: 0.72 ± 0.031	3.599ThrAsp: 3.599 ± 0.075	4.411ThrGlu: 4.411 ± 0.077	2.157ThrPhe: 2.157 ± 0.048	4.86ThrGly: 4.86 ± 0.084	0.868ThrHis: 0.868 ± 0.032	3.752ThrIle: 3.752 ± 0.064	3.056ThrLys: 3.056 ± 0.06	4.82ThrLeu: 4.82 ± 0.08	1.438ThrMet: 1.438 ± 0.04	1.945ThrAsn: 1.945 ± 0.047	2.295ThrPro: 2.295 ± 0.067	1.545ThrGln: 1.545 ± 0.047	2.043ThrArg: 2.043 ± 0.049	3.117ThrSer: 3.117 ± 0.06	2.919ThrThr: 2.919 ± 0.07	4.715ThrVal: 4.715 ± 0.085	0.544ThrTrp: 0.544 ± 0.024	2.185ThrTyr: 2.185 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.75ValAla: 4.75 ± 0.077	1.209ValCys: 1.209 ± 0.034	3.783ValAsp: 3.783 ± 0.073	4.554ValGlu: 4.554 ± 0.064	3.005ValPhe: 3.005 ± 0.06	4.204ValGly: 4.204 ± 0.072	1.166ValHis: 1.166 ± 0.037	5.247ValIle: 5.247 ± 0.082	4.471ValLys: 4.471 ± 0.068	6.602ValLeu: 6.602 ± 0.094	2.062ValMet: 2.062 ± 0.049	2.888ValAsn: 2.888 ± 0.063	2.528ValPro: 2.528 ± 0.055	2.277ValGln: 2.277 ± 0.049	2.909ValArg: 2.909 ± 0.061	4.512ValSer: 4.512 ± 0.08	4.261ValThr: 4.261 ± 0.089	4.629ValVal: 4.629 ± 0.073	0.55ValTrp: 0.55 ± 0.026	2.739ValTyr: 2.739 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.532TrpAla: 0.532 ± 0.023	0.147TrpCys: 0.147 ± 0.012	0.551TrpAsp: 0.551 ± 0.025	0.658TrpGlu: 0.658 ± 0.027	0.408TrpPhe: 0.408 ± 0.024	0.603TrpGly: 0.603 ± 0.029	0.186TrpHis: 0.186 ± 0.012	0.699TrpIle: 0.699 ± 0.031	0.948TrpLys: 0.948 ± 0.034	0.868TrpLeu: 0.868 ± 0.031	0.336TrpMet: 0.336 ± 0.02	0.554TrpAsn: 0.554 ± 0.025	0.203TrpPro: 0.203 ± 0.017	0.369TrpGln: 0.369 ± 0.018	0.337TrpArg: 0.337 ± 0.017	0.503TrpSer: 0.503 ± 0.023	0.435TrpThr: 0.435 ± 0.018	0.449TrpVal: 0.449 ± 0.022	0.096TrpTrp: 0.096 ± 0.01	0.391TrpTyr: 0.391 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.791TyrAla: 2.791 ± 0.059	0.664TyrCys: 0.664 ± 0.027	2.547TyrAsp: 2.547 ± 0.055	2.995TyrGlu: 2.995 ± 0.065	1.759TyrPhe: 1.759 ± 0.047	2.953TyrGly: 2.953 ± 0.057	0.971TyrHis: 0.971 ± 0.032	2.706TyrIle: 2.706 ± 0.049	2.339TyrLys: 2.339 ± 0.055	3.855TyrLeu: 3.855 ± 0.069	1.108TyrMet: 1.108 ± 0.034	1.76TyrAsn: 1.76 ± 0.046	1.465TyrPro: 1.465 ± 0.041	1.639TyrGln: 1.639 ± 0.047	2.072TyrArg: 2.072 ± 0.044	2.319TyrSer: 2.319 ± 0.05	2.356TyrThr: 2.356 ± 0.051	2.595TyrVal: 2.595 ± 0.049	0.374TyrTrp: 0.374 ± 0.021	1.912TyrTyr: 1.912 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3072 proteins (989712 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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