Amino acid dipepetide frequency for Sedimenticola thiotaurini

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.425AlaAla: 10.425 ± 0.128	1.117AlaCys: 1.117 ± 0.036	5.605AlaAsp: 5.605 ± 0.08	6.366AlaGlu: 6.366 ± 0.077	3.218AlaPhe: 3.218 ± 0.062	8.165AlaGly: 8.165 ± 0.09	1.868AlaHis: 1.868 ± 0.041	5.633AlaIle: 5.633 ± 0.076	3.199AlaLys: 3.199 ± 0.068	10.97AlaLeu: 10.97 ± 0.119	2.858AlaMet: 2.858 ± 0.054	2.828AlaAsn: 2.828 ± 0.056	3.589AlaPro: 3.589 ± 0.068	3.481AlaGln: 3.481 ± 0.059	6.263AlaArg: 6.263 ± 0.079	5.038AlaSer: 5.038 ± 0.069	4.582AlaThr: 4.582 ± 0.071	6.878AlaVal: 6.878 ± 0.087	1.256AlaTrp: 1.256 ± 0.035	2.406AlaTyr: 2.406 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.874CysAla: 0.874 ± 0.033	0.149CysCys: 0.149 ± 0.013	0.587CysAsp: 0.587 ± 0.024	0.6CysGlu: 0.6 ± 0.028	0.364CysPhe: 0.364 ± 0.02	1.03CysGly: 1.03 ± 0.032	0.376CysHis: 0.376 ± 0.02	0.545CysIle: 0.545 ± 0.025	0.294CysLys: 0.294 ± 0.017	1.004CysLeu: 1.004 ± 0.031	0.21CysMet: 0.21 ± 0.014	0.334CysAsn: 0.334 ± 0.017	0.623CysPro: 0.623 ± 0.029	0.403CysGln: 0.403 ± 0.022	0.727CysArg: 0.727 ± 0.026	0.692CysSer: 0.692 ± 0.028	0.475CysThr: 0.475 ± 0.024	0.603CysVal: 0.603 ± 0.027	0.12CysTrp: 0.12 ± 0.011	0.313CysTyr: 0.313 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.861AspAla: 4.861 ± 0.077	0.544AspCys: 0.544 ± 0.024	2.896AspAsp: 2.896 ± 0.062	3.897AspGlu: 3.897 ± 0.057	2.07AspPhe: 2.07 ± 0.045	4.237AspGly: 4.237 ± 0.075	1.262AspHis: 1.262 ± 0.033	3.251AspIle: 3.251 ± 0.062	2.092AspLys: 2.092 ± 0.046	5.962AspLeu: 5.962 ± 0.068	1.424AspMet: 1.424 ± 0.031	1.824AspAsn: 1.824 ± 0.042	3.143AspPro: 3.143 ± 0.057	2.714AspGln: 2.714 ± 0.059	3.726AspArg: 3.726 ± 0.057	3.011AspSer: 3.011 ± 0.05	2.615AspThr: 2.615 ± 0.051	3.338AspVal: 3.338 ± 0.058	0.867AspTrp: 0.867 ± 0.033	1.846AspTyr: 1.846 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.384GluAla: 6.384 ± 0.082	0.488GluCys: 0.488 ± 0.021	2.638GluAsp: 2.638 ± 0.049	3.921GluGlu: 3.921 ± 0.078	2.038GluPhe: 2.038 ± 0.046	3.951GluGly: 3.951 ± 0.065	1.396GluHis: 1.396 ± 0.039	3.917GluIle: 3.917 ± 0.064	2.966GluLys: 2.966 ± 0.065	7.198GluLeu: 7.198 ± 0.099	1.821GluMet: 1.821 ± 0.044	1.983GluAsn: 1.983 ± 0.044	2.646GluPro: 2.646 ± 0.057	4.511GluGln: 4.511 ± 0.077	4.801GluArg: 4.801 ± 0.064	3.671GluSer: 3.671 ± 0.061	3.304GluThr: 3.304 ± 0.06	4.194GluVal: 4.194 ± 0.065	0.762GluTrp: 0.762 ± 0.026	1.483GluTyr: 1.483 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.226PheAla: 3.226 ± 0.055	0.453PheCys: 0.453 ± 0.021	2.376PheAsp: 2.376 ± 0.046	2.086PheGlu: 2.086 ± 0.052	1.501PhePhe: 1.501 ± 0.045	3.095PheGly: 3.095 ± 0.056	0.801PheHis: 0.801 ± 0.027	2.149PheIle: 2.149 ± 0.047	1.264PheLys: 1.264 ± 0.036	3.501PheLeu: 3.501 ± 0.063	0.899PheMet: 0.899 ± 0.034	1.394PheAsn: 1.394 ± 0.043	1.578PhePro: 1.578 ± 0.039	1.357PheGln: 1.357 ± 0.034	2.07PheArg: 2.07 ± 0.046	2.685PheSer: 2.685 ± 0.053	2.008PheThr: 2.008 ± 0.047	2.332PheVal: 2.332 ± 0.055	0.506PheTrp: 0.506 ± 0.025	1.149PheTyr: 1.149 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	6.467GlyAla: 6.467 ± 0.095	1.066GlyCys: 1.066 ± 0.036	4.276GlyAsp: 4.276 ± 0.063	4.948GlyGlu: 4.948 ± 0.068	3.249GlyPhe: 3.249 ± 0.057	5.882GlyGly: 5.882 ± 0.071	1.748GlyHis: 1.748 ± 0.044	4.962GlyIle: 4.962 ± 0.069	3.431GlyLys: 3.431 ± 0.062	8.461GlyLeu: 8.461 ± 0.109	2.473GlyMet: 2.473 ± 0.048	2.433GlyAsn: 2.433 ± 0.049	2.515GlyPro: 2.515 ± 0.048	3.176GlyGln: 3.176 ± 0.063	4.743GlyArg: 4.743 ± 0.069	4.458GlySer: 4.458 ± 0.073	3.714GlyThr: 3.714 ± 0.061	5.92GlyVal: 5.92 ± 0.082	1.192GlyTrp: 1.192 ± 0.035	2.608GlyTyr: 2.608 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.932HisAla: 1.932 ± 0.041	0.312HisCys: 0.312 ± 0.014	1.18HisAsp: 1.18 ± 0.035	1.189HisGlu: 1.189 ± 0.029	0.956HisPhe: 0.956 ± 0.028	1.724HisGly: 1.724 ± 0.046	0.669HisHis: 0.669 ± 0.024	1.18HisIle: 1.18 ± 0.036	0.74HisLys: 0.74 ± 0.029	2.415HisLeu: 2.415 ± 0.047	0.543HisMet: 0.543 ± 0.022	0.719HisAsn: 0.719 ± 0.024	1.498HisPro: 1.498 ± 0.041	1.11HisGln: 1.11 ± 0.029	1.448HisArg: 1.448 ± 0.04	1.185HisSer: 1.185 ± 0.034	1.076HisThr: 1.076 ± 0.03	1.181HisVal: 1.181 ± 0.036	0.364HisTrp: 0.364 ± 0.019	0.8HisTyr: 0.8 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.771IleAla: 5.771 ± 0.082	0.689IleCys: 0.689 ± 0.023	3.657IleAsp: 3.657 ± 0.057	3.976IleGlu: 3.976 ± 0.064	1.764IlePhe: 1.764 ± 0.044	4.744IleGly: 4.744 ± 0.067	1.236IleHis: 1.236 ± 0.037	2.967IleIle: 2.967 ± 0.05	2.241IleLys: 2.241 ± 0.048	5.39IleLeu: 5.39 ± 0.085	1.208IleMet: 1.208 ± 0.035	2.253IleAsn: 2.253 ± 0.046	2.989IlePro: 2.989 ± 0.066	2.216IleGln: 2.216 ± 0.043	3.849IleArg: 3.849 ± 0.068	3.77IleSer: 3.77 ± 0.057	3.219IleThr: 3.219 ± 0.061	3.386IleVal: 3.386 ± 0.061	0.62IleTrp: 0.62 ± 0.028	1.543IleTyr: 1.543 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	3.54LysAla: 3.54 ± 0.067	0.257LysCys: 0.257 ± 0.019	1.751LysAsp: 1.751 ± 0.048	2.286LysGlu: 2.286 ± 0.062	0.972LysPhe: 0.972 ± 0.031	2.742LysGly: 2.742 ± 0.062	0.797LysHis: 0.797 ± 0.025	2.079LysIle: 2.079 ± 0.043	2.017LysLys: 2.017 ± 0.076	3.894LysLeu: 3.894 ± 0.061	0.962LysMet: 0.962 ± 0.035	1.17LysAsn: 1.17 ± 0.034	2.097LysPro: 2.097 ± 0.052	2.092LysGln: 2.092 ± 0.044	2.876LysArg: 2.876 ± 0.057	2.241LysSer: 2.241 ± 0.053	1.875LysThr: 1.875 ± 0.044	2.643LysVal: 2.643 ± 0.059	0.381LysTrp: 0.381 ± 0.017	0.87LysTyr: 0.87 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	11.206LeuAla: 11.206 ± 0.125	1.05LeuCys: 1.05 ± 0.034	6.306LeuAsp: 6.306 ± 0.086	7.245LeuGlu: 7.245 ± 0.09	4.644LeuPhe: 4.644 ± 0.089	8.207LeuGly: 8.207 ± 0.104	2.353LeuHis: 2.353 ± 0.046	6.244LeuIle: 6.244 ± 0.078	4.448LeuLys: 4.448 ± 0.073	13.382LeuLeu: 13.382 ± 0.183	2.731LeuMet: 2.731 ± 0.05	3.534LeuAsn: 3.534 ± 0.061	5.597LeuPro: 5.597 ± 0.085	4.505LeuGln: 4.505 ± 0.075	6.423LeuArg: 6.423 ± 0.084	6.768LeuSer: 6.768 ± 0.086	5.714LeuThr: 5.714 ± 0.081	7.815LeuVal: 7.815 ± 0.102	1.157LeuTrp: 1.157 ± 0.035	2.63LeuTyr: 2.63 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	2.787MetAla: 2.787 ± 0.053	0.172MetCys: 0.172 ± 0.012	1.539MetAsp: 1.539 ± 0.039	1.718MetGlu: 1.718 ± 0.043	0.744MetPhe: 0.744 ± 0.028	2.095MetGly: 2.095 ± 0.051	0.513MetHis: 0.513 ± 0.021	1.438MetIle: 1.438 ± 0.041	1.187MetLys: 1.187 ± 0.033	2.835MetLeu: 2.835 ± 0.044	0.68MetMet: 0.68 ± 0.033	0.958MetAsn: 0.958 ± 0.033	1.304MetPro: 1.304 ± 0.036	1.081MetGln: 1.081 ± 0.032	1.499MetArg: 1.499 ± 0.039	1.714MetSer: 1.714 ± 0.037	1.393MetThr: 1.393 ± 0.036	1.863MetVal: 1.863 ± 0.045	0.172MetTrp: 0.172 ± 0.012	0.429MetTyr: 0.429 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.673AsnAla: 2.673 ± 0.056	0.368AsnCys: 0.368 ± 0.019	1.527AsnAsp: 1.527 ± 0.041	1.635AsnGlu: 1.635 ± 0.04	0.996AsnPhe: 0.996 ± 0.031	2.524AsnGly: 2.524 ± 0.05	0.771AsnHis: 0.771 ± 0.027	1.858AsnIle: 1.858 ± 0.041	1.093AsnLys: 1.093 ± 0.036	3.51AsnLeu: 3.51 ± 0.057	0.812AsnMet: 0.812 ± 0.028	1.077AsnAsn: 1.077 ± 0.04	2.142AsnPro: 2.142 ± 0.044	1.507AsnGln: 1.507 ± 0.039	2.431AsnArg: 2.431 ± 0.056	1.883AsnSer: 1.883 ± 0.048	1.482AsnThr: 1.482 ± 0.046	1.803AsnVal: 1.803 ± 0.041	0.465AsnTrp: 0.465 ± 0.021	0.937AsnTyr: 0.937 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	4.762ProAla: 4.762 ± 0.077	0.411ProCys: 0.411 ± 0.019	3.481ProAsp: 3.481 ± 0.061	4.103ProGlu: 4.103 ± 0.063	1.822ProPhe: 1.822 ± 0.039	4.066ProGly: 4.066 ± 0.058	0.956ProHis: 0.956 ± 0.03	2.332ProIle: 2.332 ± 0.052	1.53ProLys: 1.53 ± 0.052	5.117ProLeu: 5.117 ± 0.082	1.152ProMet: 1.152 ± 0.035	1.243ProAsn: 1.243 ± 0.034	2.065ProPro: 2.065 ± 0.052	1.722ProGln: 1.722 ± 0.04	2.346ProArg: 2.346 ± 0.053	2.27ProSer: 2.27 ± 0.045	2.22ProThr: 2.22 ± 0.048	4.044ProVal: 4.044 ± 0.065	0.598ProTrp: 0.598 ± 0.025	1.308ProTyr: 1.308 ± 0.043	0.0ProXaa: 0.0 ± 0.0
Gln	4.94GlnAla: 4.94 ± 0.091	0.348GlnCys: 0.348 ± 0.021	1.839GlnAsp: 1.839 ± 0.039	2.671GlnGlu: 2.671 ± 0.054	1.491GlnPhe: 1.491 ± 0.034	3.198GlnGly: 3.198 ± 0.062	1.025GlnHis: 1.025 ± 0.035	2.431GlnIle: 2.431 ± 0.048	1.416GlnLys: 1.416 ± 0.039	5.457GlnLeu: 5.457 ± 0.103	1.096GlnMet: 1.096 ± 0.031	1.074GlnAsn: 1.074 ± 0.033	2.156GlnPro: 2.156 ± 0.046	3.004GlnGln: 3.004 ± 0.081	3.306GlnArg: 3.306 ± 0.063	2.269GlnSer: 2.269 ± 0.05	1.935GlnThr: 1.935 ± 0.042	3.475GlnVal: 3.475 ± 0.063	0.557GlnTrp: 0.557 ± 0.024	0.99GlnTyr: 0.99 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	5.338ArgAla: 5.338 ± 0.064	0.67ArgCys: 0.67 ± 0.024	3.603ArgAsp: 3.603 ± 0.053	4.559ArgGlu: 4.559 ± 0.077	2.836ArgPhe: 2.836 ± 0.057	3.972ArgGly: 3.972 ± 0.062	1.645ArgHis: 1.645 ± 0.037	4.049ArgIle: 4.049 ± 0.056	2.492ArgLys: 2.492 ± 0.063	7.922ArgLeu: 7.922 ± 0.093	1.813ArgMet: 1.813 ± 0.04	2.101ArgAsn: 2.101 ± 0.051	2.784ArgPro: 2.784 ± 0.054	3.377ArgGln: 3.377 ± 0.063	4.458ArgArg: 4.458 ± 0.078	3.357ArgSer: 3.357 ± 0.065	2.777ArgThr: 2.777 ± 0.062	4.597ArgVal: 4.597 ± 0.066	0.91ArgTrp: 0.91 ± 0.029	2.083ArgTyr: 2.083 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	5.457SerAla: 5.457 ± 0.078	0.618SerCys: 0.618 ± 0.03	3.317SerAsp: 3.317 ± 0.058	3.343SerGlu: 3.343 ± 0.052	2.132SerPhe: 2.132 ± 0.048	5.448SerGly: 5.448 ± 0.077	1.327SerHis: 1.327 ± 0.034	3.15SerIle: 3.15 ± 0.059	1.861SerLys: 1.861 ± 0.044	6.445SerLeu: 6.445 ± 0.075	1.552SerMet: 1.552 ± 0.038	1.782SerAsn: 1.782 ± 0.037	2.655SerPro: 2.655 ± 0.052	2.194SerGln: 2.194 ± 0.051	4.003SerArg: 4.003 ± 0.074	3.346SerSer: 3.346 ± 0.061	2.689SerThr: 2.689 ± 0.052	3.812SerVal: 3.812 ± 0.059	0.691SerTrp: 0.691 ± 0.027	1.525SerTyr: 1.525 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	4.772ThrAla: 4.772 ± 0.062	0.467ThrCys: 0.467 ± 0.02	2.727ThrAsp: 2.727 ± 0.055	2.824ThrGlu: 2.824 ± 0.051	1.678ThrPhe: 1.678 ± 0.043	4.638ThrGly: 4.638 ± 0.073	1.134ThrHis: 1.134 ± 0.033	2.788ThrIle: 2.788 ± 0.048	1.332ThrLys: 1.332 ± 0.039	6.421ThrLeu: 6.421 ± 0.092	0.975ThrMet: 0.975 ± 0.03	1.308ThrAsn: 1.308 ± 0.034	3.054ThrPro: 3.054 ± 0.056	1.744ThrGln: 1.744 ± 0.038	3.222ThrArg: 3.222 ± 0.057	2.477ThrSer: 2.477 ± 0.045	2.661ThrThr: 2.661 ± 0.044	3.55ThrVal: 3.55 ± 0.058	0.53ThrTrp: 0.53 ± 0.018	1.193ThrTyr: 1.193 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	7.189ValAla: 7.189 ± 0.097	0.723ValCys: 0.723 ± 0.025	4.217ValAsp: 4.217 ± 0.067	4.65ValGlu: 4.65 ± 0.068	2.345ValPhe: 2.345 ± 0.05	4.991ValGly: 4.991 ± 0.078	1.328ValHis: 1.328 ± 0.033	4.446ValIle: 4.446 ± 0.074	2.601ValLys: 2.601 ± 0.059	7.026ValLeu: 7.026 ± 0.103	2.028ValMet: 2.028 ± 0.045	2.285ValAsn: 2.285 ± 0.039	3.101ValPro: 3.101 ± 0.053	2.405ValGln: 2.405 ± 0.044	4.013ValArg: 4.013 ± 0.067	4.232ValSer: 4.232 ± 0.065	3.961ValThr: 3.961 ± 0.061	5.609ValVal: 5.609 ± 0.092	0.766ValTrp: 0.766 ± 0.03	1.569ValTyr: 1.569 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.916TrpAla: 0.916 ± 0.034	0.134TrpCys: 0.134 ± 0.012	0.598TrpAsp: 0.598 ± 0.02	0.685TrpGlu: 0.685 ± 0.025	0.523TrpPhe: 0.523 ± 0.025	0.884TrpGly: 0.884 ± 0.033	0.31TrpHis: 0.31 ± 0.017	0.737TrpIle: 0.737 ± 0.027	0.453TrpLys: 0.453 ± 0.022	1.754TrpLeu: 1.754 ± 0.051	0.36TrpMet: 0.36 ± 0.02	0.39TrpAsn: 0.39 ± 0.022	0.572TrpPro: 0.572 ± 0.024	0.706TrpGln: 0.706 ± 0.027	0.902TrpArg: 0.902 ± 0.03	0.717TrpSer: 0.717 ± 0.027	0.473TrpThr: 0.473 ± 0.023	0.87TrpVal: 0.87 ± 0.026	0.201TrpTrp: 0.201 ± 0.014	0.334TrpTyr: 0.334 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.225TyrAla: 2.225 ± 0.047	0.289TyrCys: 0.289 ± 0.018	1.461TyrAsp: 1.461 ± 0.04	1.374TyrGlu: 1.374 ± 0.034	1.087TyrPhe: 1.087 ± 0.036	2.128TyrGly: 2.128 ± 0.057	0.702TyrHis: 0.702 ± 0.025	1.332TyrIle: 1.332 ± 0.034	0.884TyrLys: 0.884 ± 0.029	3.3TyrLeu: 3.3 ± 0.059	0.522TyrMet: 0.522 ± 0.021	0.806TyrAsn: 0.806 ± 0.027	1.439TyrPro: 1.439 ± 0.036	1.374TyrGln: 1.374 ± 0.036	2.237TyrArg: 2.237 ± 0.051	1.56TyrSer: 1.56 ± 0.041	1.325TyrThr: 1.325 ± 0.04	1.568TyrVal: 1.568 ± 0.04	0.404TyrTrp: 0.404 ± 0.017	0.861TyrTyr: 0.861 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3407 proteins (1070962 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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