Amino acid dipepetide frequency for Xanthophyllomyces dendrorhous virus L1A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.246AlaAla: 6.246 ± 0.239
0.694AlaCys: 0.694 ± 0.451
1.388AlaAsp: 1.388 ± 0.053
4.164AlaGlu: 4.164 ± 0.795
4.858AlaPhe: 4.858 ± 2.572
2.082AlaGly: 2.082 ± 0.398
2.776AlaHis: 2.776 ± 0.848
6.246AlaIle: 6.246 ± 0.716
4.858AlaLys: 4.858 ± 0.292
7.634AlaLeu: 7.634 ± 1.723
5.552AlaMet: 5.552 ± 0.212
4.164AlaAsn: 4.164 ± 1.75
2.776AlaPro: 2.776 ± 2.015
2.082AlaGln: 2.082 ± 0.557
0.694AlaArg: 0.694 ± 0.504
6.94AlaSer: 6.94 ± 1.219
2.776AlaThr: 2.776 ± 1.803
2.776AlaVal: 2.776 ± 1.803
0.0AlaTrp: 0.0 ± 0.0
2.082AlaTyr: 2.082 ± 0.398
0.0AlaXaa: 0.0 ± 0.0
Cys
0.694CysAla: 0.694 ± 0.451
0.0CysCys: 0.0 ± 0.0
2.082CysAsp: 2.082 ± 1.352
0.694CysGlu: 0.694 ± 0.451
0.694CysPhe: 0.694 ± 0.504
0.694CysGly: 0.694 ± 0.504
0.694CysHis: 0.694 ± 0.504
0.0CysIle: 0.0 ± 0.0
1.388CysLys: 1.388 ± 0.053
1.388CysLeu: 1.388 ± 0.901
0.694CysMet: 0.694 ± 0.451
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.694CysArg: 0.694 ± 0.504
0.0CysSer: 0.0 ± 0.0
0.694CysThr: 0.694 ± 0.451
0.694CysVal: 0.694 ± 0.504
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.246AspAla: 6.246 ± 1.193
0.694AspCys: 0.694 ± 0.451
3.47AspAsp: 3.47 ± 0.345
2.082AspGlu: 2.082 ± 0.557
4.164AspPhe: 4.164 ± 1.113
2.082AspGly: 2.082 ± 0.557
0.694AspHis: 0.694 ± 0.451
2.776AspIle: 2.776 ± 0.848
1.388AspLys: 1.388 ± 0.053
2.776AspLeu: 2.776 ± 1.803
2.776AspMet: 2.776 ± 1.06
2.776AspAsn: 2.776 ± 1.06
1.388AspPro: 1.388 ± 0.053
2.776AspGln: 2.776 ± 0.848
5.552AspArg: 5.552 ± 0.742
4.164AspSer: 4.164 ± 0.795
2.776AspThr: 2.776 ± 1.06
6.94AspVal: 6.94 ± 2.174
0.694AspTrp: 0.694 ± 0.451
2.776AspTyr: 2.776 ± 1.06
0.0AspXaa: 0.0 ± 0.0
Glu
4.858GluAla: 4.858 ± 0.292
0.694GluCys: 0.694 ± 0.504
5.552GluAsp: 5.552 ± 1.166
4.858GluGlu: 4.858 ± 0.663
1.388GluPhe: 1.388 ± 0.053
1.388GluGly: 1.388 ± 1.007
0.0GluHis: 0.0 ± 0.0
4.164GluIle: 4.164 ± 2.068
3.47GluLys: 3.47 ± 1.299
4.858GluLeu: 4.858 ± 0.663
3.47GluMet: 3.47 ± 0.646
4.858GluAsn: 4.858 ± 2.201
1.388GluPro: 1.388 ± 0.053
2.776GluGln: 2.776 ± 0.848
2.082GluArg: 2.082 ± 0.557
4.858GluSer: 4.858 ± 1.246
2.082GluThr: 2.082 ± 0.557
4.164GluVal: 4.164 ± 1.113
0.694GluTrp: 0.694 ± 0.451
3.47GluTyr: 3.47 ± 0.345
0.0GluXaa: 0.0 ± 0.0
Phe
5.552PheAla: 5.552 ± 0.742
0.694PheCys: 0.694 ± 0.451
2.082PheAsp: 2.082 ± 1.511
4.858PheGlu: 4.858 ± 0.292
1.388PhePhe: 1.388 ± 0.901
2.776PheGly: 2.776 ± 1.06
1.388PheHis: 1.388 ± 0.053
2.082PheIle: 2.082 ± 0.398
2.776PheLys: 2.776 ± 0.106
2.082PheLeu: 2.082 ± 0.557
2.082PheMet: 2.082 ± 0.557
2.082PheAsn: 2.082 ± 0.557
1.388PhePro: 1.388 ± 0.901
0.694PheGln: 0.694 ± 0.504
2.082PheArg: 2.082 ± 0.398
4.164PheSer: 4.164 ± 0.159
2.776PheThr: 2.776 ± 1.06
2.776PheVal: 2.776 ± 1.06
0.0PheTrp: 0.0 ± 0.0
1.388PheTyr: 1.388 ± 0.053
0.0PheXaa: 0.0 ± 0.0
Gly
3.47GlyAla: 3.47 ± 0.345
0.0GlyCys: 0.0 ± 0.0
2.082GlyAsp: 2.082 ± 0.398
2.776GlyGlu: 2.776 ± 2.015
0.694GlyPhe: 0.694 ± 0.451
2.776GlyGly: 2.776 ± 0.106
1.388GlyHis: 1.388 ± 1.007
2.776GlyIle: 2.776 ± 1.803
3.47GlyLys: 3.47 ± 0.345
2.776GlyLeu: 2.776 ± 0.106
2.776GlyMet: 2.776 ± 0.106
1.388GlyAsn: 1.388 ± 0.901
0.694GlyPro: 0.694 ± 0.504
1.388GlyGln: 1.388 ± 0.053
7.634GlyArg: 7.634 ± 1.14
2.776GlySer: 2.776 ± 0.106
4.164GlyThr: 4.164 ± 0.159
6.246GlyVal: 6.246 ± 1.193
2.082GlyTrp: 2.082 ± 0.398
1.388GlyTyr: 1.388 ± 1.007
0.0GlyXaa: 0.0 ± 0.0
His
0.694HisAla: 0.694 ± 0.504
0.694HisCys: 0.694 ± 0.504
1.388HisAsp: 1.388 ± 1.007
3.47HisGlu: 3.47 ± 2.519
2.082HisPhe: 2.082 ± 1.352
1.388HisGly: 1.388 ± 1.007
0.694HisHis: 0.694 ± 0.451
1.388HisIle: 1.388 ± 0.053
2.776HisLys: 2.776 ± 0.848
0.694HisLeu: 0.694 ± 0.504
0.0HisMet: 0.0 ± 0.0
1.388HisAsn: 1.388 ± 0.053
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.694HisArg: 0.694 ± 0.451
2.776HisSer: 2.776 ± 0.848
1.388HisThr: 1.388 ± 1.007
1.388HisVal: 1.388 ± 1.007
0.0HisTrp: 0.0 ± 0.0
0.694HisTyr: 0.694 ± 0.504
0.0HisXaa: 0.0 ± 0.0
Ile
4.164IleAla: 4.164 ± 0.159
0.694IleCys: 0.694 ± 0.451
2.776IleAsp: 2.776 ± 0.848
2.082IleGlu: 2.082 ± 0.398
2.082IlePhe: 2.082 ± 1.352
2.776IleGly: 2.776 ± 0.848
2.776IleHis: 2.776 ± 0.106
1.388IleIle: 1.388 ± 0.901
5.552IleLys: 5.552 ± 2.651
4.164IleLeu: 4.164 ± 0.159
0.0IleMet: 0.0 ± 0.0
4.164IleAsn: 4.164 ± 1.113
3.47IlePro: 3.47 ± 1.564
2.082IleGln: 2.082 ± 0.557
2.776IleArg: 2.776 ± 0.848
4.164IleSer: 4.164 ± 1.75
6.246IleThr: 6.246 ± 1.67
0.694IleVal: 0.694 ± 0.504
0.0IleTrp: 0.0 ± 0.0
4.858IleTyr: 4.858 ± 1.246
0.0IleXaa: 0.0 ± 0.0
Lys
6.94LysAla: 6.94 ± 0.69
2.082LysCys: 2.082 ± 1.352
6.246LysAsp: 6.246 ± 0.716
2.776LysGlu: 2.776 ± 0.848
4.164LysPhe: 4.164 ± 0.159
4.164LysGly: 4.164 ± 0.795
0.694LysHis: 0.694 ± 0.451
3.47LysIle: 3.47 ± 1.299
0.694LysLys: 0.694 ± 0.504
1.388LysLeu: 1.388 ± 0.053
2.082LysMet: 2.082 ± 0.398
2.082LysAsn: 2.082 ± 1.352
0.694LysPro: 0.694 ± 0.504
5.552LysGln: 5.552 ± 1.697
2.082LysArg: 2.082 ± 0.557
4.858LysSer: 4.858 ± 1.246
3.47LysThr: 3.47 ± 0.61
2.082LysVal: 2.082 ± 1.511
0.0LysTrp: 0.0 ± 0.0
2.082LysTyr: 2.082 ± 0.398
0.0LysXaa: 0.0 ± 0.0
Leu
3.47LeuAla: 3.47 ± 1.564
0.694LeuCys: 0.694 ± 0.451
2.776LeuAsp: 2.776 ± 0.848
4.858LeuGlu: 4.858 ± 0.663
5.552LeuPhe: 5.552 ± 3.075
1.388LeuGly: 1.388 ± 0.053
4.858LeuHis: 4.858 ± 2.572
5.552LeuIle: 5.552 ± 1.697
2.776LeuLys: 2.776 ± 0.848
4.164LeuLeu: 4.164 ± 0.159
0.0LeuMet: 0.0 ± 0.339
4.858LeuAsn: 4.858 ± 0.663
6.94LeuPro: 6.94 ± 0.265
0.694LeuGln: 0.694 ± 0.451
6.246LeuArg: 6.246 ± 0.239
4.858LeuSer: 4.858 ± 1.246
5.552LeuThr: 5.552 ± 0.212
4.858LeuVal: 4.858 ± 1.246
0.694LeuTrp: 0.694 ± 0.451
2.776LeuTyr: 2.776 ± 0.106
0.0LeuXaa: 0.0 ± 0.0
Met
2.082MetAla: 2.082 ± 1.352
0.0MetCys: 0.0 ± 0.0
1.388MetAsp: 1.388 ± 0.053
2.082MetGlu: 2.082 ± 1.352
0.694MetPhe: 0.694 ± 0.504
2.082MetGly: 2.082 ± 0.557
1.388MetHis: 1.388 ± 1.007
0.694MetIle: 0.694 ± 0.504
2.776MetLys: 2.776 ± 0.848
3.47MetLeu: 3.47 ± 0.61
1.388MetMet: 1.388 ± 1.007
2.082MetAsn: 2.082 ± 0.557
3.47MetPro: 3.47 ± 0.345
2.082MetGln: 2.082 ± 1.352
1.388MetArg: 1.388 ± 0.053
0.694MetSer: 0.694 ± 0.451
2.082MetThr: 2.082 ± 1.352
5.552MetVal: 5.552 ± 3.075
0.694MetTrp: 0.694 ± 0.451
0.694MetTyr: 0.694 ± 0.504
0.0MetXaa: 0.0 ± 0.0
Asn
3.47AsnAla: 3.47 ± 0.61
0.694AsnCys: 0.694 ± 0.451
2.082AsnAsp: 2.082 ± 1.352
2.776AsnGlu: 2.776 ± 0.848
1.388AsnPhe: 1.388 ± 0.053
2.082AsnGly: 2.082 ± 1.352
0.0AsnHis: 0.0 ± 0.0
0.694AsnIle: 0.694 ± 0.451
2.776AsnLys: 2.776 ± 0.106
2.776AsnLeu: 2.776 ± 0.106
2.776AsnMet: 2.776 ± 0.106
0.694AsnAsn: 0.694 ± 0.451
0.694AsnPro: 0.694 ± 0.504
1.388AsnGln: 1.388 ± 0.053
6.94AsnArg: 6.94 ± 1.644
2.776AsnSer: 2.776 ± 0.106
2.082AsnThr: 2.082 ± 0.557
9.715AsnVal: 9.715 ± 0.584
0.694AsnTrp: 0.694 ± 0.504
3.47AsnTyr: 3.47 ± 0.61
0.0AsnXaa: 0.0 ± 0.0
Pro
1.388ProAla: 1.388 ± 1.007
0.694ProCys: 0.694 ± 0.504
1.388ProAsp: 1.388 ± 0.053
2.776ProGlu: 2.776 ± 1.06
0.694ProPhe: 0.694 ± 0.451
3.47ProGly: 3.47 ± 0.345
0.0ProHis: 0.0 ± 0.0
1.388ProIle: 1.388 ± 1.007
2.776ProLys: 2.776 ± 1.803
3.47ProLeu: 3.47 ± 1.564
2.776ProMet: 2.776 ± 1.06
1.388ProAsn: 1.388 ± 0.053
0.694ProPro: 0.694 ± 0.504
2.082ProGln: 2.082 ± 0.398
2.082ProArg: 2.082 ± 0.557
4.164ProSer: 4.164 ± 3.022
0.694ProThr: 0.694 ± 0.451
4.858ProVal: 4.858 ± 1.617
0.694ProTrp: 0.694 ± 0.504
1.388ProTyr: 1.388 ± 0.053
0.0ProXaa: 0.0 ± 0.0
Gln
1.388GlnAla: 1.388 ± 0.901
0.694GlnCys: 0.694 ± 0.504
0.694GlnAsp: 0.694 ± 0.504
2.776GlnGlu: 2.776 ± 1.06
0.694GlnPhe: 0.694 ± 0.451
2.082GlnGly: 2.082 ± 0.398
0.694GlnHis: 0.694 ± 0.451
1.388GlnIle: 1.388 ± 0.053
0.694GlnLys: 0.694 ± 0.451
2.082GlnLeu: 2.082 ± 1.352
2.776GlnMet: 2.776 ± 0.106
2.082GlnAsn: 2.082 ± 1.352
0.694GlnPro: 0.694 ± 0.504
0.694GlnGln: 0.694 ± 0.451
2.776GlnArg: 2.776 ± 0.848
4.858GlnSer: 4.858 ± 2.201
2.082GlnThr: 2.082 ± 1.511
3.47GlnVal: 3.47 ± 0.61
1.388GlnTrp: 1.388 ± 0.901
4.164GlnTyr: 4.164 ± 0.795
0.0GlnXaa: 0.0 ± 0.0
Arg
4.858ArgAla: 4.858 ± 0.292
0.694ArgCys: 0.694 ± 0.451
5.552ArgAsp: 5.552 ± 1.697
4.858ArgGlu: 4.858 ± 2.201
2.776ArgPhe: 2.776 ± 0.106
2.776ArgGly: 2.776 ± 0.848
1.388ArgHis: 1.388 ± 0.053
3.47ArgIle: 3.47 ± 1.299
2.776ArgLys: 2.776 ± 1.06
4.164ArgLeu: 4.164 ± 0.795
2.082ArgMet: 2.082 ± 0.398
0.694ArgAsn: 0.694 ± 0.504
4.164ArgPro: 4.164 ± 0.159
2.082ArgGln: 2.082 ± 0.398
2.082ArgArg: 2.082 ± 0.398
6.246ArgSer: 6.246 ± 1.67
1.388ArgThr: 1.388 ± 0.053
5.552ArgVal: 5.552 ± 1.166
0.694ArgTrp: 0.694 ± 0.451
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.552SerAla: 5.552 ± 2.121
0.0SerCys: 0.0 ± 0.0
2.776SerAsp: 2.776 ± 0.848
3.47SerGlu: 3.47 ± 0.61
2.082SerPhe: 2.082 ± 0.557
8.328SerGly: 8.328 ± 0.318
1.388SerHis: 1.388 ± 1.007
6.246SerIle: 6.246 ± 2.148
6.246SerLys: 6.246 ± 1.193
6.246SerLeu: 6.246 ± 0.239
2.082SerMet: 2.082 ± 0.398
4.858SerAsn: 4.858 ± 0.663
2.776SerPro: 2.776 ± 1.06
6.246SerGln: 6.246 ± 1.193
3.47SerArg: 3.47 ± 1.299
6.246SerSer: 6.246 ± 0.239
2.082SerThr: 2.082 ± 0.398
5.552SerVal: 5.552 ± 1.697
1.388SerTrp: 1.388 ± 0.053
3.47SerTyr: 3.47 ± 0.345
0.0SerXaa: 0.0 ± 0.0
Thr
3.47ThrAla: 3.47 ± 1.564
0.0ThrCys: 0.0 ± 0.0
5.552ThrAsp: 5.552 ± 0.212
0.694ThrGlu: 0.694 ± 0.504
4.858ThrPhe: 4.858 ± 0.292
2.082ThrGly: 2.082 ± 0.557
0.694ThrHis: 0.694 ± 0.504
5.552ThrIle: 5.552 ± 0.212
4.858ThrLys: 4.858 ± 0.663
3.47ThrLeu: 3.47 ± 1.564
1.388ThrMet: 1.388 ± 0.901
2.082ThrAsn: 2.082 ± 0.557
3.47ThrPro: 3.47 ± 0.61
1.388ThrGln: 1.388 ± 0.053
2.082ThrArg: 2.082 ± 0.557
5.552ThrSer: 5.552 ± 0.742
2.776ThrThr: 2.776 ± 1.803
4.164ThrVal: 4.164 ± 1.113
0.0ThrTrp: 0.0 ± 0.0
2.082ThrTyr: 2.082 ± 0.398
0.0ThrXaa: 0.0 ± 0.0
Val
2.776ValAla: 2.776 ± 1.06
0.694ValCys: 0.694 ± 0.504
5.552ValAsp: 5.552 ± 2.121
2.776ValGlu: 2.776 ± 0.106
1.388ValPhe: 1.388 ± 0.901
4.164ValGly: 4.164 ± 1.75
2.082ValHis: 2.082 ± 0.557
4.164ValIle: 4.164 ± 0.159
4.858ValLys: 4.858 ± 2.572
13.185ValLeu: 13.185 ± 0.026
0.694ValMet: 0.694 ± 0.504
6.246ValAsn: 6.246 ± 1.193
2.082ValPro: 2.082 ± 1.511
2.082ValGln: 2.082 ± 0.398
4.858ValArg: 4.858 ± 0.292
8.328ValSer: 8.328 ± 1.272
7.634ValThr: 7.634 ± 2.678
4.164ValVal: 4.164 ± 0.159
0.694ValTrp: 0.694 ± 0.504
0.694ValTyr: 0.694 ± 0.451
0.0ValXaa: 0.0 ± 0.0
Trp
0.694TrpAla: 0.694 ± 0.451
0.694TrpCys: 0.694 ± 0.504
1.388TrpAsp: 1.388 ± 1.007
1.388TrpGlu: 1.388 ± 0.901
1.388TrpPhe: 1.388 ± 0.053
0.694TrpGly: 0.694 ± 0.451
0.0TrpHis: 0.0 ± 0.0
0.694TrpIle: 0.694 ± 0.504
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.694TrpGln: 0.694 ± 0.451
1.388TrpArg: 1.388 ± 0.053
1.388TrpSer: 1.388 ± 0.901
0.694TrpThr: 0.694 ± 0.451
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.694TrpTyr: 0.694 ± 0.451
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.776TyrAla: 2.776 ± 0.848
0.0TyrCys: 0.0 ± 0.0
2.776TyrAsp: 2.776 ± 0.106
4.858TyrGlu: 4.858 ± 0.292
2.082TyrPhe: 2.082 ± 0.557
3.47TyrGly: 3.47 ± 0.345
0.0TyrHis: 0.0 ± 0.0
2.776TyrIle: 2.776 ± 0.106
0.694TyrLys: 0.694 ± 0.451
3.47TyrLeu: 3.47 ± 1.299
0.694TyrMet: 0.694 ± 0.451
2.082TyrAsn: 2.082 ± 0.398
2.082TyrPro: 2.082 ± 0.557
1.388TyrGln: 1.388 ± 1.007
0.694TyrArg: 0.694 ± 0.504
0.694TyrSer: 0.694 ± 0.504
2.776TyrThr: 2.776 ± 0.106
3.47TyrVal: 3.47 ± 0.345
1.388TyrTrp: 1.388 ± 0.053
0.694TyrTyr: 0.694 ± 0.451
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1442 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski