Amino acid dipepetide frequency for Feline morbillivirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.134AlaAla: 2.134 ± 0.437
0.854AlaCys: 0.854 ± 0.363
1.067AlaAsp: 1.067 ± 0.305
1.921AlaGlu: 1.921 ± 0.854
2.134AlaPhe: 2.134 ± 0.684
2.134AlaGly: 2.134 ± 0.949
0.427AlaHis: 0.427 ± 0.257
4.481AlaIle: 4.481 ± 1.186
2.347AlaLys: 2.347 ± 0.403
5.122AlaLeu: 5.122 ± 1.329
0.854AlaMet: 0.854 ± 0.417
2.347AlaAsn: 2.347 ± 0.426
1.921AlaPro: 1.921 ± 0.59
1.707AlaGln: 1.707 ± 0.546
2.134AlaArg: 2.134 ± 0.548
3.628AlaSer: 3.628 ± 1.17
2.134AlaThr: 2.134 ± 0.882
3.414AlaVal: 3.414 ± 0.681
0.213AlaTrp: 0.213 ± 0.128
2.347AlaTyr: 2.347 ± 0.876
0.0AlaXaa: 0.0 ± 0.0
Cys
0.64CysAla: 0.64 ± 0.29
0.213CysCys: 0.213 ± 0.128
1.067CysAsp: 1.067 ± 0.305
0.427CysGlu: 0.427 ± 0.225
1.28CysPhe: 1.28 ± 0.547
1.28CysGly: 1.28 ± 0.77
0.213CysHis: 0.213 ± 0.128
1.494CysIle: 1.494 ± 0.481
0.854CysLys: 0.854 ± 0.397
1.28CysLeu: 1.28 ± 0.379
0.64CysMet: 0.64 ± 0.29
0.213CysAsn: 0.213 ± 0.128
0.427CysPro: 0.427 ± 0.248
1.067CysGln: 1.067 ± 0.299
1.494CysArg: 1.494 ± 0.698
1.494CysSer: 1.494 ± 0.509
1.28CysThr: 1.28 ± 0.535
0.213CysVal: 0.213 ± 0.128
0.213CysTrp: 0.213 ± 0.128
0.854CysTyr: 0.854 ± 0.325
0.0CysXaa: 0.0 ± 0.0
Asp
1.067AspAla: 1.067 ± 0.356
0.64AspCys: 0.64 ± 0.385
3.841AspAsp: 3.841 ± 0.812
3.628AspGlu: 3.628 ± 0.983
1.067AspPhe: 1.067 ± 0.282
2.347AspGly: 2.347 ± 0.74
2.134AspHis: 2.134 ± 0.802
6.615AspIle: 6.615 ± 0.747
2.988AspLys: 2.988 ± 0.689
5.335AspLeu: 5.335 ± 0.57
0.64AspMet: 0.64 ± 0.295
3.841AspAsn: 3.841 ± 0.556
4.481AspPro: 4.481 ± 0.833
2.561AspGln: 2.561 ± 0.691
1.921AspArg: 1.921 ± 0.495
3.201AspSer: 3.201 ± 0.891
3.841AspThr: 3.841 ± 0.763
2.347AspVal: 2.347 ± 0.616
0.213AspTrp: 0.213 ± 0.128
2.774AspTyr: 2.774 ± 0.795
0.0AspXaa: 0.0 ± 0.0
Glu
1.28GluAla: 1.28 ± 0.852
1.707GluCys: 1.707 ± 0.443
1.921GluAsp: 1.921 ± 0.542
2.347GluGlu: 2.347 ± 0.351
1.707GluPhe: 1.707 ± 0.436
2.561GluGly: 2.561 ± 0.941
0.854GluHis: 0.854 ± 0.434
5.335GluIle: 5.335 ± 0.581
1.921GluLys: 1.921 ± 0.725
5.762GluLeu: 5.762 ± 0.844
2.134GluMet: 2.134 ± 0.762
2.347GluAsn: 2.347 ± 1.062
0.854GluPro: 0.854 ± 0.349
1.707GluGln: 1.707 ± 0.17
2.347GluArg: 2.347 ± 0.578
5.548GluSer: 5.548 ± 0.571
4.055GluThr: 4.055 ± 1.252
3.201GluVal: 3.201 ± 0.61
0.64GluTrp: 0.64 ± 0.274
1.28GluTyr: 1.28 ± 0.581
0.0GluXaa: 0.0 ± 0.0
Phe
1.707PheAla: 1.707 ± 0.458
1.067PheCys: 1.067 ± 0.449
3.201PheAsp: 3.201 ± 0.564
1.494PheGlu: 1.494 ± 0.471
1.707PhePhe: 1.707 ± 0.814
2.134PheGly: 2.134 ± 1.122
0.213PheHis: 0.213 ± 0.128
2.347PheIle: 2.347 ± 1.049
2.988PheLys: 2.988 ± 1.508
3.841PheLeu: 3.841 ± 0.929
0.854PheMet: 0.854 ± 0.294
2.774PheAsn: 2.774 ± 0.767
0.854PhePro: 0.854 ± 0.325
0.213PheGln: 0.213 ± 0.128
2.347PheArg: 2.347 ± 0.682
2.988PheSer: 2.988 ± 0.507
1.067PheThr: 1.067 ± 0.308
2.134PheVal: 2.134 ± 0.645
0.64PheTrp: 0.64 ± 0.385
1.067PheTyr: 1.067 ± 0.465
0.0PheXaa: 0.0 ± 0.0
Gly
2.134GlyAla: 2.134 ± 0.708
0.213GlyCys: 0.213 ± 0.128
2.561GlyAsp: 2.561 ± 0.527
3.414GlyGlu: 3.414 ± 1.218
2.561GlyPhe: 2.561 ± 0.545
2.988GlyGly: 2.988 ± 1.096
1.707GlyHis: 1.707 ± 0.56
5.122GlyIle: 5.122 ± 0.593
1.707GlyLys: 1.707 ± 0.464
6.402GlyLeu: 6.402 ± 1.117
1.707GlyMet: 1.707 ± 0.43
2.774GlyAsn: 2.774 ± 1.23
1.494GlyPro: 1.494 ± 0.717
2.347GlyGln: 2.347 ± 0.487
2.561GlyArg: 2.561 ± 0.47
3.201GlySer: 3.201 ± 0.688
3.414GlyThr: 3.414 ± 1.237
3.841GlyVal: 3.841 ± 1.964
0.64GlyTrp: 0.64 ± 0.397
2.134GlyTyr: 2.134 ± 1.024
0.0GlyXaa: 0.0 ± 0.0
His
1.28HisAla: 1.28 ± 0.377
0.427HisCys: 0.427 ± 0.233
0.64HisAsp: 0.64 ± 0.254
2.134HisGlu: 2.134 ± 0.57
0.427HisPhe: 0.427 ± 0.257
0.64HisGly: 0.64 ± 0.266
0.213HisHis: 0.213 ± 0.128
2.774HisIle: 2.774 ± 0.791
1.28HisLys: 1.28 ± 0.413
2.988HisLeu: 2.988 ± 0.964
0.0HisMet: 0.0 ± 0.0
1.067HisAsn: 1.067 ± 0.422
1.28HisPro: 1.28 ± 0.293
0.64HisGln: 0.64 ± 0.473
0.854HisArg: 0.854 ± 0.344
1.921HisSer: 1.921 ± 0.86
0.213HisThr: 0.213 ± 0.243
0.213HisVal: 0.213 ± 0.257
0.213HisTrp: 0.213 ± 0.128
0.854HisTyr: 0.854 ± 0.343
0.0HisXaa: 0.0 ± 0.0
Ile
5.335IleAla: 5.335 ± 1.31
0.64IleCys: 0.64 ± 0.298
5.975IleAsp: 5.975 ± 0.879
3.628IleGlu: 3.628 ± 0.809
3.841IlePhe: 3.841 ± 0.915
4.481IleGly: 4.481 ± 1.575
2.347IleHis: 2.347 ± 0.676
10.67IleIle: 10.67 ± 3.017
7.256IleLys: 7.256 ± 0.583
7.896IleLeu: 7.896 ± 0.569
3.201IleMet: 3.201 ± 1.47
7.042IleAsn: 7.042 ± 1.172
3.628IlePro: 3.628 ± 0.882
3.841IleGln: 3.841 ± 0.824
5.335IleArg: 5.335 ± 1.089
5.975IleSer: 5.975 ± 1.223
8.536IleThr: 8.536 ± 2.672
3.628IleVal: 3.628 ± 0.606
0.427IleTrp: 0.427 ± 0.35
3.841IleTyr: 3.841 ± 0.619
0.0IleXaa: 0.0 ± 0.0
Lys
3.201LysAla: 3.201 ± 0.836
1.494LysCys: 1.494 ± 0.481
3.414LysAsp: 3.414 ± 1.015
2.134LysGlu: 2.134 ± 0.381
1.921LysPhe: 1.921 ± 0.407
3.414LysGly: 3.414 ± 0.359
0.64LysHis: 0.64 ± 0.473
4.481LysIle: 4.481 ± 1.035
2.561LysLys: 2.561 ± 0.254
7.469LysLeu: 7.469 ± 1.323
1.707LysMet: 1.707 ± 0.699
2.988LysAsn: 2.988 ± 0.866
1.707LysPro: 1.707 ± 0.476
1.921LysGln: 1.921 ± 0.5
2.561LysArg: 2.561 ± 0.981
5.122LysSer: 5.122 ± 0.839
2.774LysThr: 2.774 ± 0.719
3.414LysVal: 3.414 ± 0.813
0.213LysTrp: 0.213 ± 0.128
3.201LysTyr: 3.201 ± 1.275
0.0LysXaa: 0.0 ± 0.0
Leu
5.548LeuAla: 5.548 ± 1.496
1.28LeuCys: 1.28 ± 0.297
6.829LeuAsp: 6.829 ± 0.607
5.975LeuGlu: 5.975 ± 1.279
3.628LeuPhe: 3.628 ± 0.708
5.548LeuGly: 5.548 ± 1.138
3.414LeuHis: 3.414 ± 0.759
8.323LeuIle: 8.323 ± 1.66
4.481LeuLys: 4.481 ± 1.238
10.883LeuLeu: 10.883 ± 1.151
2.134LeuMet: 2.134 ± 0.551
6.402LeuAsn: 6.402 ± 1.125
3.201LeuPro: 3.201 ± 0.695
1.921LeuGln: 1.921 ± 0.623
4.908LeuArg: 4.908 ± 1.101
11.737LeuSer: 11.737 ± 1.613
6.615LeuThr: 6.615 ± 0.863
6.615LeuVal: 6.615 ± 0.749
0.854LeuTrp: 0.854 ± 0.369
3.628LeuTyr: 3.628 ± 1.12
0.0LeuXaa: 0.0 ± 0.0
Met
1.067MetAla: 1.067 ± 0.305
0.0MetCys: 0.0 ± 0.0
0.213MetAsp: 0.213 ± 0.257
1.28MetGlu: 1.28 ± 0.701
0.213MetPhe: 0.213 ± 0.128
1.28MetGly: 1.28 ± 0.662
0.427MetHis: 0.427 ± 0.233
2.347MetIle: 2.347 ± 0.422
1.067MetLys: 1.067 ± 0.52
1.494MetLeu: 1.494 ± 0.515
0.0MetMet: 0.0 ± 0.0
2.347MetAsn: 2.347 ± 0.606
0.427MetPro: 0.427 ± 0.248
1.28MetGln: 1.28 ± 0.76
0.854MetArg: 0.854 ± 0.325
3.201MetSer: 3.201 ± 0.434
2.134MetThr: 2.134 ± 0.564
1.921MetVal: 1.921 ± 1.236
0.427MetTrp: 0.427 ± 0.257
1.921MetTyr: 1.921 ± 0.682
0.0MetXaa: 0.0 ± 0.0
Asn
2.774AsnAla: 2.774 ± 0.638
1.067AsnCys: 1.067 ± 0.759
2.774AsnAsp: 2.774 ± 0.887
2.988AsnGlu: 2.988 ± 0.941
1.707AsnPhe: 1.707 ± 0.667
2.774AsnGly: 2.774 ± 0.466
1.067AsnHis: 1.067 ± 0.52
5.335AsnIle: 5.335 ± 0.918
4.695AsnLys: 4.695 ± 0.614
5.762AsnLeu: 5.762 ± 0.669
1.707AsnMet: 1.707 ± 0.377
2.988AsnAsn: 2.988 ± 0.666
3.201AsnPro: 3.201 ± 0.793
2.347AsnGln: 2.347 ± 0.55
2.774AsnArg: 2.774 ± 0.475
7.256AsnSer: 7.256 ± 1.178
2.347AsnThr: 2.347 ± 0.516
1.28AsnVal: 1.28 ± 0.548
0.64AsnTrp: 0.64 ± 0.29
3.201AsnTyr: 3.201 ± 1.104
0.0AsnXaa: 0.0 ± 0.0
Pro
1.28ProAla: 1.28 ± 0.755
0.213ProCys: 0.213 ± 0.243
2.988ProAsp: 2.988 ± 0.89
2.561ProGlu: 2.561 ± 0.655
1.494ProPhe: 1.494 ± 0.898
2.774ProGly: 2.774 ± 1.846
0.854ProHis: 0.854 ± 0.463
3.841ProIle: 3.841 ± 0.616
2.347ProLys: 2.347 ± 0.725
4.055ProLeu: 4.055 ± 0.734
0.854ProMet: 0.854 ± 0.496
2.561ProAsn: 2.561 ± 0.231
2.347ProPro: 2.347 ± 1.045
0.64ProGln: 0.64 ± 0.332
2.774ProArg: 2.774 ± 0.428
5.335ProSer: 5.335 ± 0.804
1.921ProThr: 1.921 ± 0.59
1.707ProVal: 1.707 ± 0.441
0.213ProTrp: 0.213 ± 0.26
2.347ProTyr: 2.347 ± 0.821
0.0ProXaa: 0.0 ± 0.0
Gln
1.921GlnAla: 1.921 ± 0.873
1.067GlnCys: 1.067 ± 0.246
1.921GlnAsp: 1.921 ± 1.198
2.134GlnGlu: 2.134 ± 0.773
0.854GlnPhe: 0.854 ± 0.45
2.774GlnGly: 2.774 ± 0.485
0.427GlnHis: 0.427 ± 0.257
3.841GlnIle: 3.841 ± 0.607
1.707GlnLys: 1.707 ± 0.434
4.055GlnLeu: 4.055 ± 0.592
0.854GlnMet: 0.854 ± 0.359
1.707GlnAsn: 1.707 ± 0.799
1.494GlnPro: 1.494 ± 0.724
1.921GlnGln: 1.921 ± 0.469
1.707GlnArg: 1.707 ± 0.498
2.347GlnSer: 2.347 ± 0.487
1.067GlnThr: 1.067 ± 0.356
1.921GlnVal: 1.921 ± 0.318
0.64GlnTrp: 0.64 ± 0.385
1.921GlnTyr: 1.921 ± 0.372
0.0GlnXaa: 0.0 ± 0.0
Arg
2.347ArgAla: 2.347 ± 0.647
1.067ArgCys: 1.067 ± 0.543
3.201ArgAsp: 3.201 ± 0.468
2.347ArgGlu: 2.347 ± 0.593
2.347ArgPhe: 2.347 ± 0.62
2.347ArgGly: 2.347 ± 0.517
0.854ArgHis: 0.854 ± 0.344
4.481ArgIle: 4.481 ± 0.95
2.988ArgLys: 2.988 ± 0.881
5.548ArgLeu: 5.548 ± 1.126
1.494ArgMet: 1.494 ± 0.464
2.988ArgAsn: 2.988 ± 0.47
1.494ArgPro: 1.494 ± 0.281
0.854ArgGln: 0.854 ± 0.359
2.347ArgArg: 2.347 ± 1.033
5.548ArgSer: 5.548 ± 1.047
1.707ArgThr: 1.707 ± 0.433
2.774ArgVal: 2.774 ± 0.31
0.213ArgTrp: 0.213 ± 0.236
1.707ArgTyr: 1.707 ± 0.352
0.0ArgXaa: 0.0 ± 0.0
Ser
2.134SerAla: 2.134 ± 0.461
1.707SerCys: 1.707 ± 0.56
5.762SerAsp: 5.762 ± 0.779
3.414SerGlu: 3.414 ± 0.464
2.774SerPhe: 2.774 ± 1.136
5.122SerGly: 5.122 ± 1.556
2.134SerHis: 2.134 ± 0.736
7.896SerIle: 7.896 ± 2.894
5.548SerLys: 5.548 ± 1.064
8.536SerLeu: 8.536 ± 1.017
2.347SerMet: 2.347 ± 0.427
5.335SerAsn: 5.335 ± 1.068
4.695SerPro: 4.695 ± 1.369
4.695SerGln: 4.695 ± 0.829
3.414SerArg: 3.414 ± 0.712
10.67SerSer: 10.67 ± 2.522
7.469SerThr: 7.469 ± 1.088
5.335SerVal: 5.335 ± 0.984
1.707SerTrp: 1.707 ± 0.714
2.774SerTyr: 2.774 ± 0.733
0.0SerXaa: 0.0 ± 0.0
Thr
2.774ThrAla: 2.774 ± 0.715
0.854ThrCys: 0.854 ± 0.359
2.561ThrAsp: 2.561 ± 0.434
3.201ThrGlu: 3.201 ± 0.498
1.921ThrPhe: 1.921 ± 0.336
2.988ThrGly: 2.988 ± 1.066
0.213ThrHis: 0.213 ± 0.236
8.323ThrIle: 8.323 ± 1.304
4.908ThrLys: 4.908 ± 0.901
5.762ThrLeu: 5.762 ± 1.058
0.854ThrMet: 0.854 ± 0.513
3.414ThrAsn: 3.414 ± 0.695
2.347ThrPro: 2.347 ± 0.742
1.494ThrGln: 1.494 ± 0.335
2.774ThrArg: 2.774 ± 0.95
6.402ThrSer: 6.402 ± 1.001
3.628ThrThr: 3.628 ± 0.441
2.561ThrVal: 2.561 ± 1.052
1.28ThrTrp: 1.28 ± 0.77
2.347ThrTyr: 2.347 ± 0.723
0.0ThrXaa: 0.0 ± 0.0
Val
2.347ValAla: 2.347 ± 0.593
0.213ValCys: 0.213 ± 0.26
2.561ValAsp: 2.561 ± 0.661
2.134ValGlu: 2.134 ± 0.993
1.921ValPhe: 1.921 ± 0.372
3.628ValGly: 3.628 ± 0.67
1.28ValHis: 1.28 ± 0.45
5.122ValIle: 5.122 ± 1.311
1.707ValLys: 1.707 ± 0.691
5.335ValLeu: 5.335 ± 0.806
0.64ValMet: 0.64 ± 0.473
2.988ValAsn: 2.988 ± 0.896
3.841ValPro: 3.841 ± 0.454
2.774ValGln: 2.774 ± 0.555
2.988ValArg: 2.988 ± 1.168
3.201ValSer: 3.201 ± 0.991
3.414ValThr: 3.414 ± 0.336
1.494ValVal: 1.494 ± 0.678
0.213ValTrp: 0.213 ± 0.236
2.561ValTyr: 2.561 ± 0.917
0.0ValXaa: 0.0 ± 0.0
Trp
0.854TrpAla: 0.854 ± 0.513
0.427TrpCys: 0.427 ± 0.487
1.067TrpAsp: 1.067 ± 0.246
0.427TrpGlu: 0.427 ± 0.257
0.64TrpPhe: 0.64 ± 0.385
0.0TrpGly: 0.0 ± 0.0
0.213TrpHis: 0.213 ± 0.128
0.854TrpIle: 0.854 ± 0.477
0.427TrpLys: 0.427 ± 0.236
0.854TrpLeu: 0.854 ± 0.229
0.0TrpMet: 0.0 ± 0.0
0.427TrpAsn: 0.427 ± 0.225
0.427TrpPro: 0.427 ± 0.233
0.0TrpGln: 0.0 ± 0.0
0.64TrpArg: 0.64 ± 0.277
1.067TrpSer: 1.067 ± 0.334
0.213TrpThr: 0.213 ± 0.128
0.427TrpVal: 0.427 ± 0.257
0.213TrpTrp: 0.213 ± 0.243
0.64TrpTyr: 0.64 ± 0.28
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.494TyrAla: 1.494 ± 0.691
1.494TyrCys: 1.494 ± 0.542
1.921TyrAsp: 1.921 ± 0.919
1.921TyrGlu: 1.921 ± 0.6
1.494TyrPhe: 1.494 ± 0.928
1.707TyrGly: 1.707 ± 0.441
0.427TyrHis: 0.427 ± 0.248
3.841TyrIle: 3.841 ± 0.591
2.774TyrLys: 2.774 ± 0.861
5.548TyrLeu: 5.548 ± 2.319
1.067TyrMet: 1.067 ± 0.334
2.134TyrAsn: 2.134 ± 0.567
2.988TyrPro: 2.988 ± 0.536
2.347TyrGln: 2.347 ± 0.977
1.921TyrArg: 1.921 ± 0.448
3.628TyrSer: 3.628 ± 1.046
2.774TyrThr: 2.774 ± 0.922
1.921TyrVal: 1.921 ± 0.495
0.0TyrTrp: 0.0 ± 0.0
2.347TyrTyr: 2.347 ± 0.516
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4687 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski