Amino acid dipepetide frequency for Hop latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.605AlaAla: 8.605 ± 0.995
0.717AlaCys: 0.717 ± 0.385
3.944AlaAsp: 3.944 ± 1.197
7.171AlaGlu: 7.171 ± 1.277
3.227AlaPhe: 3.227 ± 0.593
5.02AlaGly: 5.02 ± 0.807
1.793AlaHis: 1.793 ± 0.631
4.661AlaIle: 4.661 ± 1.132
5.02AlaLys: 5.02 ± 0.863
8.605AlaLeu: 8.605 ± 0.923
1.076AlaMet: 1.076 ± 0.442
2.868AlaAsn: 2.868 ± 1.301
2.51AlaPro: 2.51 ± 0.569
2.151AlaGln: 2.151 ± 1.155
4.303AlaArg: 4.303 ± 1.253
5.02AlaSer: 5.02 ± 1.658
2.868AlaThr: 2.868 ± 0.805
6.454AlaVal: 6.454 ± 1.047
0.359AlaTrp: 0.359 ± 0.192
1.793AlaTyr: 1.793 ± 0.631
0.0AlaXaa: 0.0 ± 0.0
Cys
1.793CysAla: 1.793 ± 1.024
0.359CysCys: 0.359 ± 0.192
0.717CysAsp: 0.717 ± 0.653
1.076CysGlu: 1.076 ± 0.577
2.51CysPhe: 2.51 ± 0.825
1.793CysGly: 1.793 ± 1.624
0.359CysHis: 0.359 ± 0.773
1.076CysIle: 1.076 ± 0.577
1.793CysLys: 1.793 ± 0.545
3.586CysLeu: 3.586 ± 1.997
0.359CysMet: 0.359 ± 0.192
1.434CysAsn: 1.434 ± 0.537
1.434CysPro: 1.434 ± 1.078
0.359CysGln: 0.359 ± 0.809
1.793CysArg: 1.793 ± 0.714
1.434CysSer: 1.434 ± 0.77
2.868CysThr: 2.868 ± 1.539
3.586CysVal: 3.586 ± 1.688
0.0CysTrp: 0.0 ± 0.0
0.717CysTyr: 0.717 ± 0.653
0.0CysXaa: 0.0 ± 0.0
Asp
2.868AspAla: 2.868 ± 0.962
0.717AspCys: 0.717 ± 0.567
2.51AspAsp: 2.51 ± 0.952
5.02AspGlu: 5.02 ± 0.997
1.793AspPhe: 1.793 ± 0.598
3.586AspGly: 3.586 ± 1.053
0.359AspHis: 0.359 ± 0.192
2.151AspIle: 2.151 ± 1.005
2.51AspLys: 2.51 ± 0.374
5.02AspLeu: 5.02 ± 1.142
2.151AspMet: 2.151 ± 0.979
1.793AspAsn: 1.793 ± 0.598
2.51AspPro: 2.51 ± 1.729
0.359AspGln: 0.359 ± 0.192
2.151AspArg: 2.151 ± 0.644
3.227AspSer: 3.227 ± 1.457
1.793AspThr: 1.793 ± 0.631
6.095AspVal: 6.095 ± 1.471
0.717AspTrp: 0.717 ± 0.567
3.586AspTyr: 3.586 ± 0.873
0.0AspXaa: 0.0 ± 0.0
Glu
5.737GluAla: 5.737 ± 1.371
0.717GluCys: 0.717 ± 0.385
3.586GluAsp: 3.586 ± 1.091
6.095GluGlu: 6.095 ± 0.946
2.151GluPhe: 2.151 ± 0.867
5.378GluGly: 5.378 ± 0.591
2.868GluHis: 2.868 ± 0.67
1.793GluIle: 1.793 ± 0.482
2.868GluLys: 2.868 ± 0.962
7.53GluLeu: 7.53 ± 1.775
1.793GluMet: 1.793 ± 1.042
2.51GluAsn: 2.51 ± 0.374
3.227GluPro: 3.227 ± 1.156
2.868GluGln: 2.868 ± 0.574
3.944GluArg: 3.944 ± 1.616
5.02GluSer: 5.02 ± 1.429
2.51GluThr: 2.51 ± 0.952
3.944GluVal: 3.944 ± 1.118
1.076GluTrp: 1.076 ± 0.49
1.434GluTyr: 1.434 ± 1.078
0.0GluXaa: 0.0 ± 0.0
Phe
2.868PheAla: 2.868 ± 0.453
1.434PheCys: 1.434 ± 0.537
2.868PheAsp: 2.868 ± 0.453
5.737PheGlu: 5.737 ± 1.371
1.434PhePhe: 1.434 ± 0.77
3.944PheGly: 3.944 ± 2.353
0.717PheHis: 0.717 ± 0.653
2.868PheIle: 2.868 ± 0.977
1.076PheLys: 1.076 ± 0.711
5.02PheLeu: 5.02 ± 0.895
1.076PheMet: 1.076 ± 0.577
1.793PheAsn: 1.793 ± 0.962
1.076PhePro: 1.076 ± 0.574
1.793PheGln: 1.793 ± 1.045
2.868PheArg: 2.868 ± 1.539
2.868PheSer: 2.868 ± 1.083
3.227PheThr: 3.227 ± 0.883
2.51PheVal: 2.51 ± 0.917
0.359PheTrp: 0.359 ± 0.192
1.434PheTyr: 1.434 ± 0.867
0.0PheXaa: 0.0 ± 0.0
Gly
3.944GlyAla: 3.944 ± 0.546
2.151GlyCys: 2.151 ± 1.339
3.227GlyAsp: 3.227 ± 0.985
3.227GlyGlu: 3.227 ± 0.825
1.076GlyPhe: 1.076 ± 0.788
3.944GlyGly: 3.944 ± 0.878
0.359GlyHis: 0.359 ± 0.809
1.793GlyIle: 1.793 ± 0.962
4.661GlyLys: 4.661 ± 0.791
7.888GlyLeu: 7.888 ± 2.241
0.359GlyMet: 0.359 ± 0.192
0.717GlyAsn: 0.717 ± 0.567
1.793GlyPro: 1.793 ± 0.545
2.151GlyGln: 2.151 ± 0.386
6.812GlyArg: 6.812 ± 2.462
5.02GlySer: 5.02 ± 0.997
3.227GlyThr: 3.227 ± 1.172
5.378GlyVal: 5.378 ± 2.27
1.434GlyTrp: 1.434 ± 0.537
1.793GlyTyr: 1.793 ± 0.962
0.0GlyXaa: 0.0 ± 0.0
His
1.793HisAla: 1.793 ± 0.778
0.717HisCys: 0.717 ± 1.269
1.434HisAsp: 1.434 ± 0.77
0.717HisGlu: 0.717 ± 0.385
0.717HisPhe: 0.717 ± 0.539
1.076HisGly: 1.076 ± 0.694
0.717HisHis: 0.717 ± 0.385
0.717HisIle: 0.717 ± 0.539
2.151HisLys: 2.151 ± 0.386
3.944HisLeu: 3.944 ± 1.489
0.717HisMet: 0.717 ± 0.58
1.434HisAsn: 1.434 ± 0.867
0.717HisPro: 0.717 ± 0.385
0.0HisGln: 0.0 ± 0.0
2.151HisArg: 2.151 ± 1.538
2.51HisSer: 2.51 ± 1.013
0.0HisThr: 0.0 ± 0.0
2.151HisVal: 2.151 ± 0.662
0.0HisTrp: 0.0 ± 0.0
1.076HisTyr: 1.076 ± 0.577
0.0HisXaa: 0.0 ± 0.0
Ile
4.661IleAla: 4.661 ± 0.694
1.793IleCys: 1.793 ± 0.545
2.868IleAsp: 2.868 ± 0.969
3.227IleGlu: 3.227 ± 1.732
1.076IlePhe: 1.076 ± 0.502
1.793IleGly: 1.793 ± 0.631
0.359IleHis: 0.359 ± 0.192
0.717IleIle: 0.717 ± 0.567
2.868IleLys: 2.868 ± 0.962
3.944IleLeu: 3.944 ± 0.607
1.076IleMet: 1.076 ± 0.577
1.434IleAsn: 1.434 ± 0.673
0.359IlePro: 0.359 ± 0.773
0.717IleGln: 0.717 ± 0.539
3.227IleArg: 3.227 ± 2.384
2.868IleSer: 2.868 ± 1.237
1.793IleThr: 1.793 ± 0.545
4.661IleVal: 4.661 ± 2.374
0.717IleTrp: 0.717 ± 0.729
1.793IleTyr: 1.793 ± 0.962
0.0IleXaa: 0.0 ± 0.0
Lys
3.944LysAla: 3.944 ± 1.5
0.717LysCys: 0.717 ± 0.385
3.227LysAsp: 3.227 ± 2.362
1.076LysGlu: 1.076 ± 0.49
3.944LysPhe: 3.944 ± 1.118
3.586LysGly: 3.586 ± 1.435
1.434LysHis: 1.434 ± 0.77
1.793LysIle: 1.793 ± 1.042
5.737LysLys: 5.737 ± 1.939
8.247LysLeu: 8.247 ± 1.082
0.359LysMet: 0.359 ± 0.192
2.51LysAsn: 2.51 ± 1.086
4.303LysPro: 4.303 ± 1.444
1.076LysGln: 1.076 ± 0.49
2.868LysArg: 2.868 ± 0.969
4.303LysSer: 4.303 ± 0.868
2.151LysThr: 2.151 ± 1.117
3.944LysVal: 3.944 ± 1.001
0.0LysTrp: 0.0 ± 0.0
2.868LysTyr: 2.868 ± 0.969
0.0LysXaa: 0.0 ± 0.0
Leu
7.53LeuAla: 7.53 ± 1.122
5.378LeuCys: 5.378 ± 1.393
5.737LeuAsp: 5.737 ± 1.33
9.681LeuGlu: 9.681 ± 1.36
4.661LeuPhe: 4.661 ± 1.273
6.095LeuGly: 6.095 ± 0.863
2.868LeuHis: 2.868 ± 1.356
3.586LeuIle: 3.586 ± 0.495
5.737LeuLys: 5.737 ± 1.939
13.266LeuLeu: 13.266 ± 3.453
1.076LeuMet: 1.076 ± 0.49
3.944LeuAsn: 3.944 ± 1.045
6.095LeuPro: 6.095 ± 1.284
4.303LeuGln: 4.303 ± 1.901
7.888LeuArg: 7.888 ± 1.271
6.454LeuSer: 6.454 ± 1.655
5.02LeuThr: 5.02 ± 3.242
6.095LeuVal: 6.095 ± 2.393
2.151LeuTrp: 2.151 ± 0.884
3.227LeuTyr: 3.227 ± 1.247
0.0LeuXaa: 0.0 ± 0.0
Met
2.51MetAla: 2.51 ± 0.952
0.717MetCys: 0.717 ± 0.385
1.076MetAsp: 1.076 ± 0.502
0.717MetGlu: 0.717 ± 0.385
0.359MetPhe: 0.359 ± 0.773
1.076MetGly: 1.076 ± 0.49
0.359MetHis: 0.359 ± 0.192
1.434MetIle: 1.434 ± 0.867
1.434MetLys: 1.434 ± 0.481
2.868MetLeu: 2.868 ± 1.301
0.359MetMet: 0.359 ± 0.691
0.717MetAsn: 0.717 ± 0.385
1.076MetPro: 1.076 ± 0.694
0.717MetGln: 0.717 ± 0.385
1.434MetArg: 1.434 ± 0.77
0.359MetSer: 0.359 ± 0.192
0.717MetThr: 0.717 ± 0.567
1.076MetVal: 1.076 ± 0.49
0.717MetTrp: 0.717 ± 0.385
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.868AsnAla: 2.868 ± 1.323
2.151AsnCys: 2.151 ± 0.763
1.434AsnAsp: 1.434 ± 0.77
2.51AsnGlu: 2.51 ± 0.86
2.51AsnPhe: 2.51 ± 0.732
1.793AsnGly: 1.793 ± 0.482
1.076AsnHis: 1.076 ± 0.577
0.359AsnIle: 0.359 ± 0.192
3.944AsnLys: 3.944 ± 2.007
4.661AsnLeu: 4.661 ± 1.281
1.793AsnMet: 1.793 ± 1.321
1.793AsnAsn: 1.793 ± 1.814
1.793AsnPro: 1.793 ± 1.67
0.717AsnGln: 0.717 ± 1.373
3.227AsnArg: 3.227 ± 1.141
1.793AsnSer: 1.793 ± 0.852
0.717AsnThr: 0.717 ± 0.729
1.434AsnVal: 1.434 ± 0.959
0.717AsnTrp: 0.717 ± 0.385
2.151AsnTyr: 2.151 ± 0.662
0.0AsnXaa: 0.0 ± 0.0
Pro
3.944ProAla: 3.944 ± 0.918
0.359ProCys: 0.359 ± 0.192
3.586ProAsp: 3.586 ± 0.831
2.51ProGlu: 2.51 ± 0.807
1.793ProPhe: 1.793 ± 1.024
3.227ProGly: 3.227 ± 1.709
1.793ProHis: 1.793 ± 0.778
2.151ProIle: 2.151 ± 2.001
0.359ProLys: 0.359 ± 0.192
2.51ProLeu: 2.51 ± 1.086
1.076ProMet: 1.076 ± 0.577
1.434ProAsn: 1.434 ± 1.611
2.51ProPro: 2.51 ± 1.808
1.434ProGln: 1.434 ± 0.77
3.586ProArg: 3.586 ± 0.686
2.868ProSer: 2.868 ± 1.323
2.151ProThr: 2.151 ± 2.936
3.227ProVal: 3.227 ± 1.141
0.717ProTrp: 0.717 ± 0.729
1.793ProTyr: 1.793 ± 1.042
0.0ProXaa: 0.0 ± 0.0
Gln
1.076GlnAla: 1.076 ± 0.49
1.076GlnCys: 1.076 ± 1.776
0.717GlnAsp: 0.717 ± 0.385
0.717GlnGlu: 0.717 ± 0.385
1.793GlnPhe: 1.793 ± 0.962
2.51GlnGly: 2.51 ± 1.409
0.717GlnHis: 0.717 ± 0.385
2.51GlnIle: 2.51 ± 0.732
1.793GlnLys: 1.793 ± 1.042
3.944GlnLeu: 3.944 ± 1.027
1.076GlnMet: 1.076 ± 0.49
1.434GlnAsn: 1.434 ± 0.77
1.076GlnPro: 1.076 ± 0.959
1.434GlnGln: 1.434 ± 0.481
1.434GlnArg: 1.434 ± 1.135
3.944GlnSer: 3.944 ± 0.918
0.359GlnThr: 0.359 ± 0.635
2.51GlnVal: 2.51 ± 0.825
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
8.247ArgAla: 8.247 ± 1.19
2.151ArgCys: 2.151 ± 2.433
2.51ArgAsp: 2.51 ± 0.844
5.378ArgGlu: 5.378 ± 1.157
5.737ArgPhe: 5.737 ± 0.886
3.586ArgGly: 3.586 ± 0.831
1.434ArgHis: 1.434 ± 0.922
1.076ArgIle: 1.076 ± 0.577
4.303ArgLys: 4.303 ± 1.683
7.53ArgLeu: 7.53 ± 1.558
1.076ArgMet: 1.076 ± 0.577
2.151ArgAsn: 2.151 ± 0.662
1.434ArgPro: 1.434 ± 0.867
1.434ArgGln: 1.434 ± 0.77
5.02ArgArg: 5.02 ± 3.321
4.661ArgSer: 4.661 ± 1.332
2.151ArgThr: 2.151 ± 1.155
3.586ArgVal: 3.586 ± 3.811
1.793ArgTrp: 1.793 ± 0.631
1.434ArgTyr: 1.434 ± 0.77
0.0ArgXaa: 0.0 ± 0.0
Ser
3.944SerAla: 3.944 ± 0.89
2.51SerCys: 2.51 ± 0.86
4.661SerAsp: 4.661 ± 1.73
3.586SerGlu: 3.586 ± 0.686
3.227SerPhe: 3.227 ± 1.141
2.868SerGly: 2.868 ± 1.539
2.151SerHis: 2.151 ± 0.763
2.51SerIle: 2.51 ± 0.878
6.095SerLys: 6.095 ± 0.858
6.454SerLeu: 6.454 ± 1.216
1.076SerMet: 1.076 ± 0.74
3.227SerAsn: 3.227 ± 1.79
2.51SerPro: 2.51 ± 0.729
2.151SerGln: 2.151 ± 0.662
4.303SerArg: 4.303 ± 1.644
5.378SerSer: 5.378 ± 3.097
2.151SerThr: 2.151 ± 0.763
7.171SerVal: 7.171 ± 1.522
0.717SerTrp: 0.717 ± 0.385
2.51SerTyr: 2.51 ± 0.825
0.0SerXaa: 0.0 ± 0.0
Thr
2.51ThrAla: 2.51 ± 1.51
1.076ThrCys: 1.076 ± 1.072
0.717ThrAsp: 0.717 ± 0.385
3.586ThrGlu: 3.586 ± 1.001
5.02ThrPhe: 5.02 ± 1.833
2.151ThrGly: 2.151 ± 1.533
1.793ThrHis: 1.793 ± 0.545
3.227ThrIle: 3.227 ± 1.732
1.076ThrLys: 1.076 ± 1.527
3.944ThrLeu: 3.944 ± 0.848
0.717ThrMet: 0.717 ± 0.385
1.076ThrAsn: 1.076 ± 1.25
1.793ThrPro: 1.793 ± 1.045
0.717ThrGln: 0.717 ± 0.385
1.793ThrArg: 1.793 ± 1.51
3.586ThrSer: 3.586 ± 0.744
1.793ThrThr: 1.793 ± 0.854
2.151ThrVal: 2.151 ± 0.822
0.717ThrTrp: 0.717 ± 0.567
2.51ThrTyr: 2.51 ± 1.168
0.0ThrXaa: 0.0 ± 0.0
Val
6.812ValAla: 6.812 ± 2.406
3.227ValCys: 3.227 ± 0.702
4.661ValAsp: 4.661 ± 1.238
2.51ValGlu: 2.51 ± 2.14
2.151ValPhe: 2.151 ± 0.386
5.737ValGly: 5.737 ± 2.388
2.51ValHis: 2.51 ± 0.779
5.02ValIle: 5.02 ± 3.052
1.076ValLys: 1.076 ± 0.577
7.171ValLeu: 7.171 ± 1.386
0.717ValMet: 0.717 ± 1.338
2.151ValAsn: 2.151 ± 1.155
4.303ValPro: 4.303 ± 0.773
4.661ValGln: 4.661 ± 0.855
5.737ValArg: 5.737 ± 2.366
4.303ValSer: 4.303 ± 1.391
3.944ValThr: 3.944 ± 0.98
6.812ValVal: 6.812 ± 2.166
0.359ValTrp: 0.359 ± 0.192
1.793ValTyr: 1.793 ± 0.631
0.0ValXaa: 0.0 ± 0.0
Trp
0.717TrpAla: 0.717 ± 0.729
0.717TrpCys: 0.717 ± 0.385
0.359TrpAsp: 0.359 ± 0.192
0.359TrpGlu: 0.359 ± 0.192
0.717TrpPhe: 0.717 ± 0.385
1.076TrpGly: 1.076 ± 0.577
0.717TrpHis: 0.717 ± 0.385
0.359TrpIle: 0.359 ± 0.635
0.717TrpLys: 0.717 ± 0.385
1.793TrpLeu: 1.793 ± 1.125
0.0TrpMet: 0.0 ± 0.0
1.793TrpAsn: 1.793 ± 0.482
0.717TrpPro: 0.717 ± 0.653
0.0TrpGln: 0.0 ± 0.0
0.359TrpArg: 0.359 ± 0.691
0.359TrpSer: 0.359 ± 0.691
0.0TrpThr: 0.0 ± 0.0
1.793TrpVal: 1.793 ± 0.962
0.0TrpTrp: 0.0 ± 0.0
0.359TrpTyr: 0.359 ± 0.192
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.793TyrAla: 1.793 ± 0.731
0.359TyrCys: 0.359 ± 0.691
1.076TyrAsp: 1.076 ± 0.577
2.151TyrGlu: 2.151 ± 1.155
1.076TyrPhe: 1.076 ± 0.502
0.717TyrGly: 0.717 ± 0.385
0.359TyrHis: 0.359 ± 0.192
2.151TyrIle: 2.151 ± 0.662
2.868TyrLys: 2.868 ± 1.161
2.868TyrLeu: 2.868 ± 0.793
1.434TyrMet: 1.434 ± 0.481
3.227TyrAsn: 3.227 ± 0.64
1.793TyrPro: 1.793 ± 0.631
1.076TyrGln: 1.076 ± 0.577
1.793TyrArg: 1.793 ± 0.598
3.586TyrSer: 3.586 ± 1.234
2.51TyrThr: 2.51 ± 1.558
1.076TyrVal: 1.076 ± 1.25
0.359TyrTrp: 0.359 ± 0.192
0.359TyrTyr: 0.359 ± 0.192
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2790 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski