Amino acid dipepetide frequency for Macaque stool associated virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.406AlaAla: 1.406 ± 1.104
2.813AlaCys: 2.813 ± 1.789
4.219AlaAsp: 4.219 ± 1.942
0.0AlaGlu: 0.0 ± 0.0
0.0AlaPhe: 0.0 ± 0.0
2.813AlaGly: 2.813 ± 1.641
1.406AlaHis: 1.406 ± 0.895
2.813AlaIle: 2.813 ± 0.662
4.219AlaLys: 4.219 ± 1.122
8.439AlaLeu: 8.439 ± 1.638
1.406AlaMet: 1.406 ± 0.895
1.406AlaAsn: 1.406 ± 0.895
2.813AlaPro: 2.813 ± 1.789
5.626AlaGln: 5.626 ± 5.251
0.0AlaArg: 0.0 ± 0.0
9.845AlaSer: 9.845 ± 1.116
0.0AlaThr: 0.0 ± 0.0
5.626AlaVal: 5.626 ± 3.579
2.813AlaTrp: 2.813 ± 0.662
2.813AlaTyr: 2.813 ± 1.641
0.0AlaXaa: 0.0 ± 0.0
Cys
1.406CysAla: 1.406 ± 0.895
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.406CysGly: 1.406 ± 1.104
0.0CysHis: 0.0 ± 0.0
1.406CysIle: 1.406 ± 0.895
2.813CysLys: 2.813 ± 0.662
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.406CysAsn: 1.406 ± 0.895
1.406CysPro: 1.406 ± 1.104
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.406CysSer: 1.406 ± 1.104
1.406CysThr: 1.406 ± 1.104
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.406AspAla: 1.406 ± 0.895
1.406AspCys: 1.406 ± 1.104
0.0AspAsp: 0.0 ± 0.0
1.406AspGlu: 1.406 ± 1.104
1.406AspPhe: 1.406 ± 1.104
2.813AspGly: 2.813 ± 0.662
1.406AspHis: 1.406 ± 1.104
4.219AspIle: 4.219 ± 1.122
1.406AspLys: 1.406 ± 1.104
1.406AspLeu: 1.406 ± 0.895
2.813AspMet: 2.813 ± 1.789
2.813AspAsn: 2.813 ± 1.641
2.813AspPro: 2.813 ± 0.662
1.406AspGln: 1.406 ± 0.895
2.813AspArg: 2.813 ± 2.208
4.219AspSer: 4.219 ± 1.122
5.626AspThr: 5.626 ± 1.64
8.439AspVal: 8.439 ± 0.357
1.406AspTrp: 1.406 ± 1.104
5.626AspTyr: 5.626 ± 5.075
0.0AspXaa: 0.0 ± 0.0
Glu
2.813GluAla: 2.813 ± 2.208
1.406GluCys: 1.406 ± 0.895
0.0GluAsp: 0.0 ± 0.0
2.813GluGlu: 2.813 ± 0.662
2.813GluPhe: 2.813 ± 0.662
5.626GluGly: 5.626 ± 2.651
2.813GluHis: 2.813 ± 0.662
5.626GluIle: 5.626 ± 1.324
4.219GluLys: 4.219 ± 1.586
1.406GluLeu: 1.406 ± 0.895
1.406GluMet: 1.406 ± 1.104
2.813GluAsn: 2.813 ± 1.641
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
1.406GluArg: 1.406 ± 0.895
2.813GluSer: 2.813 ± 1.789
7.032GluThr: 7.032 ± 3.739
1.406GluVal: 1.406 ± 1.793
1.406GluTrp: 1.406 ± 0.895
1.406GluTyr: 1.406 ± 1.104
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
4.219PheGlu: 4.219 ± 3.312
0.0PhePhe: 0.0 ± 0.0
1.406PheGly: 1.406 ± 1.104
0.0PheHis: 0.0 ± 0.0
1.406PheIle: 1.406 ± 1.104
2.813PheLys: 2.813 ± 1.891
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
1.406PheAsn: 1.406 ± 0.895
4.219PhePro: 4.219 ± 3.318
0.0PheGln: 0.0 ± 0.0
2.813PheArg: 2.813 ± 0.662
2.813PheSer: 2.813 ± 1.789
7.032PheThr: 7.032 ± 2.775
5.626PheVal: 5.626 ± 0.985
0.0PheTrp: 0.0 ± 0.0
1.406PheTyr: 1.406 ± 1.104
0.0PheXaa: 0.0 ± 0.0
Gly
2.813GlyAla: 2.813 ± 1.641
0.0GlyCys: 0.0 ± 0.0
2.813GlyAsp: 2.813 ± 1.789
1.406GlyGlu: 1.406 ± 0.895
4.219GlyPhe: 4.219 ± 1.214
1.406GlyGly: 1.406 ± 1.793
1.406GlyHis: 1.406 ± 1.104
2.813GlyIle: 2.813 ± 0.662
5.626GlyLys: 5.626 ± 2.651
8.439GlyLeu: 8.439 ± 2.244
0.0GlyMet: 0.0 ± 0.0
2.813GlyAsn: 2.813 ± 2.208
1.406GlyPro: 1.406 ± 0.895
2.813GlyGln: 2.813 ± 1.641
5.626GlyArg: 5.626 ± 1.64
1.406GlySer: 1.406 ± 0.895
5.626GlyThr: 5.626 ± 1.918
9.845GlyVal: 9.845 ± 1.116
2.813GlyTrp: 2.813 ± 0.662
1.406GlyTyr: 1.406 ± 1.104
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.406HisGlu: 1.406 ± 0.895
0.0HisPhe: 0.0 ± 0.0
1.406HisGly: 1.406 ± 0.895
0.0HisHis: 0.0 ± 0.0
1.406HisIle: 1.406 ± 1.104
0.0HisLys: 0.0 ± 0.0
4.219HisLeu: 4.219 ± 3.312
0.0HisMet: 0.0 ± 0.0
2.813HisAsn: 2.813 ± 2.208
2.813HisPro: 2.813 ± 0.662
0.0HisGln: 0.0 ± 0.0
1.406HisArg: 1.406 ± 0.895
0.0HisSer: 0.0 ± 0.0
1.406HisThr: 1.406 ± 0.895
0.0HisVal: 0.0 ± 0.0
1.406HisTrp: 1.406 ± 0.895
1.406HisTyr: 1.406 ± 1.104
0.0HisXaa: 0.0 ± 0.0
Ile
2.813IleAla: 2.813 ± 1.789
0.0IleCys: 0.0 ± 0.0
4.219IleAsp: 4.219 ± 1.586
2.813IleGlu: 2.813 ± 1.789
2.813IlePhe: 2.813 ± 2.208
11.252IleGly: 11.252 ± 1.885
2.813IleHis: 2.813 ± 2.208
9.845IleIle: 9.845 ± 5.932
2.813IleLys: 2.813 ± 2.208
2.813IleLeu: 2.813 ± 1.789
2.813IleMet: 2.813 ± 1.789
0.0IleAsn: 0.0 ± 0.0
7.032IlePro: 7.032 ± 3.739
2.813IleGln: 2.813 ± 0.662
1.406IleArg: 1.406 ± 0.895
5.626IleSer: 5.626 ± 0.985
0.0IleThr: 0.0 ± 0.0
1.406IleVal: 1.406 ± 1.104
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.219LysAla: 4.219 ± 2.525
2.813LysCys: 2.813 ± 2.208
2.813LysAsp: 2.813 ± 2.208
2.813LysGlu: 2.813 ± 2.208
2.813LysPhe: 2.813 ± 1.789
4.219LysGly: 4.219 ± 3.312
0.0LysHis: 0.0 ± 0.0
1.406LysIle: 1.406 ± 0.895
5.626LysLys: 5.626 ± 2.651
2.813LysLeu: 2.813 ± 0.662
4.219LysMet: 4.219 ± 0.915
4.219LysAsn: 4.219 ± 1.214
1.406LysPro: 1.406 ± 1.104
1.406LysGln: 1.406 ± 1.104
2.813LysArg: 2.813 ± 1.891
4.219LysSer: 4.219 ± 1.586
1.406LysThr: 1.406 ± 1.104
4.219LysVal: 4.219 ± 1.942
2.813LysTrp: 2.813 ± 2.208
1.406LysTyr: 1.406 ± 1.793
0.0LysXaa: 0.0 ± 0.0
Leu
5.626LeuAla: 5.626 ± 3.579
0.0LeuCys: 0.0 ± 0.0
0.0LeuAsp: 0.0 ± 0.0
5.626LeuGlu: 5.626 ± 1.324
1.406LeuPhe: 1.406 ± 1.104
4.219LeuGly: 4.219 ± 3.318
0.0LeuHis: 0.0 ± 0.0
2.813LeuIle: 2.813 ± 0.662
4.219LeuLys: 4.219 ± 2.525
4.219LeuLeu: 4.219 ± 1.122
2.813LeuMet: 2.813 ± 0.662
2.813LeuAsn: 2.813 ± 0.662
4.219LeuPro: 4.219 ± 2.684
2.813LeuGln: 2.813 ± 0.662
1.406LeuArg: 1.406 ± 1.104
8.439LeuSer: 8.439 ± 3.65
4.219LeuThr: 4.219 ± 1.214
4.219LeuVal: 4.219 ± 1.586
0.0LeuTrp: 0.0 ± 0.0
7.032LeuTyr: 7.032 ± 3.482
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.813MetAsp: 2.813 ± 1.789
0.0MetGlu: 0.0 ± 0.0
1.406MetPhe: 1.406 ± 0.895
4.219MetGly: 4.219 ± 1.122
1.406MetHis: 1.406 ± 1.104
2.813MetIle: 2.813 ± 2.208
0.0MetLys: 0.0 ± 0.0
2.813MetLeu: 2.813 ± 0.662
2.813MetMet: 2.813 ± 1.63
8.439MetAsn: 8.439 ± 4.076
5.626MetPro: 5.626 ± 3.579
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.406MetSer: 1.406 ± 1.793
0.0MetThr: 0.0 ± 0.0
4.219MetVal: 4.219 ± 1.122
0.0MetTrp: 0.0 ± 0.0
2.813MetTyr: 2.813 ± 0.662
0.0MetXaa: 0.0 ± 0.0
Asn
4.219AsnAla: 4.219 ± 1.942
1.406AsnCys: 1.406 ± 0.895
4.219AsnAsp: 4.219 ± 1.214
0.0AsnGlu: 0.0 ± 0.0
1.406AsnPhe: 1.406 ± 1.793
7.032AsnGly: 7.032 ± 4.473
1.406AsnHis: 1.406 ± 0.895
1.406AsnIle: 1.406 ± 1.793
2.813AsnLys: 2.813 ± 1.641
2.813AsnLeu: 2.813 ± 0.662
0.0AsnMet: 0.0 ± 0.0
1.406AsnAsn: 1.406 ± 0.895
2.813AsnPro: 2.813 ± 1.789
2.813AsnGln: 2.813 ± 1.641
7.032AsnArg: 7.032 ± 2.165
1.406AsnSer: 1.406 ± 1.104
1.406AsnThr: 1.406 ± 0.895
5.626AsnVal: 5.626 ± 1.918
1.406AsnTrp: 1.406 ± 0.895
2.813AsnTyr: 2.813 ± 2.208
0.0AsnXaa: 0.0 ± 0.0
Pro
4.219ProAla: 4.219 ± 1.122
0.0ProCys: 0.0 ± 0.0
2.813ProAsp: 2.813 ± 0.662
0.0ProGlu: 0.0 ± 0.0
1.406ProPhe: 1.406 ± 1.104
2.813ProGly: 2.813 ± 1.789
0.0ProHis: 0.0 ± 0.0
5.626ProIle: 5.626 ± 1.324
2.813ProLys: 2.813 ± 2.208
4.219ProLeu: 4.219 ± 2.684
4.219ProMet: 4.219 ± 1.122
1.406ProAsn: 1.406 ± 0.895
4.219ProPro: 4.219 ± 2.684
2.813ProGln: 2.813 ± 1.789
4.219ProArg: 4.219 ± 2.525
4.219ProSer: 4.219 ± 1.942
2.813ProThr: 2.813 ± 1.641
2.813ProVal: 2.813 ± 1.641
0.0ProTrp: 0.0 ± 0.0
2.813ProTyr: 2.813 ± 1.641
0.0ProXaa: 0.0 ± 0.0
Gln
2.813GlnAla: 2.813 ± 1.641
0.0GlnCys: 0.0 ± 0.0
5.626GlnAsp: 5.626 ± 1.324
1.406GlnGlu: 1.406 ± 1.104
2.813GlnPhe: 2.813 ± 1.891
1.406GlnGly: 1.406 ± 0.895
0.0GlnHis: 0.0 ± 0.0
2.813GlnIle: 2.813 ± 1.789
1.406GlnLys: 1.406 ± 1.104
0.0GlnLeu: 0.0 ± 0.0
1.406GlnMet: 1.406 ± 0.895
2.813GlnAsn: 2.813 ± 0.662
1.406GlnPro: 1.406 ± 1.793
4.219GlnGln: 4.219 ± 1.122
1.406GlnArg: 1.406 ± 1.104
1.406GlnSer: 1.406 ± 1.793
4.219GlnThr: 4.219 ± 2.684
2.813GlnVal: 2.813 ± 1.891
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.219ArgAla: 4.219 ± 1.122
0.0ArgCys: 0.0 ± 0.0
5.626ArgAsp: 5.626 ± 1.64
1.406ArgGlu: 1.406 ± 1.104
2.813ArgPhe: 2.813 ± 2.208
1.406ArgGly: 1.406 ± 1.104
1.406ArgHis: 1.406 ± 0.895
2.813ArgIle: 2.813 ± 2.208
0.0ArgLys: 0.0 ± 0.0
8.439ArgLeu: 8.439 ± 2.624
2.813ArgMet: 2.813 ± 0.662
0.0ArgAsn: 0.0 ± 0.0
1.406ArgPro: 1.406 ± 0.895
2.813ArgGln: 2.813 ± 2.208
1.406ArgArg: 1.406 ± 1.104
1.406ArgSer: 1.406 ± 1.793
1.406ArgThr: 1.406 ± 0.895
0.0ArgVal: 0.0 ± 0.0
1.406ArgTrp: 1.406 ± 1.104
5.626ArgTyr: 5.626 ± 2.989
0.0ArgXaa: 0.0 ± 0.0
Ser
2.813SerAla: 2.813 ± 1.789
0.0SerCys: 0.0 ± 0.0
1.406SerAsp: 1.406 ± 1.793
4.219SerGlu: 4.219 ± 1.122
2.813SerPhe: 2.813 ± 1.789
4.219SerGly: 4.219 ± 1.122
0.0SerHis: 0.0 ± 0.0
4.219SerIle: 4.219 ± 1.586
2.813SerLys: 2.813 ± 1.641
4.219SerLeu: 4.219 ± 1.942
5.626SerMet: 5.626 ± 3.079
7.032SerAsn: 7.032 ± 2.775
0.0SerPro: 0.0 ± 0.0
2.813SerGln: 2.813 ± 0.662
1.406SerArg: 1.406 ± 1.793
5.626SerSer: 5.626 ± 5.075
7.032SerThr: 7.032 ± 1.611
4.219SerVal: 4.219 ± 3.318
2.813SerTrp: 2.813 ± 2.208
4.219SerTyr: 4.219 ± 3.318
0.0SerXaa: 0.0 ± 0.0
Thr
4.219ThrAla: 4.219 ± 1.122
1.406ThrCys: 1.406 ± 1.104
5.626ThrAsp: 5.626 ± 1.64
5.626ThrGlu: 5.626 ± 3.282
1.406ThrPhe: 1.406 ± 0.895
1.406ThrGly: 1.406 ± 1.104
0.0ThrHis: 0.0 ± 0.0
1.406ThrIle: 1.406 ± 0.895
7.032ThrLys: 7.032 ± 3.739
1.406ThrLeu: 1.406 ± 0.895
2.813ThrMet: 2.813 ± 1.789
4.219ThrAsn: 4.219 ± 1.122
1.406ThrPro: 1.406 ± 0.895
0.0ThrGln: 0.0 ± 0.0
2.813ThrArg: 2.813 ± 2.208
4.219ThrSer: 4.219 ± 1.122
5.626ThrThr: 5.626 ± 0.985
5.626ThrVal: 5.626 ± 3.579
2.813ThrTrp: 2.813 ± 1.891
4.219ThrTyr: 4.219 ± 1.122
0.0ThrXaa: 0.0 ± 0.0
Val
8.439ValAla: 8.439 ± 0.357
1.406ValCys: 1.406 ± 1.104
4.219ValAsp: 4.219 ± 1.122
7.032ValGlu: 7.032 ± 1.611
4.219ValPhe: 4.219 ± 1.942
1.406ValGly: 1.406 ± 0.895
5.626ValHis: 5.626 ± 1.324
1.406ValIle: 1.406 ± 0.895
1.406ValLys: 1.406 ± 0.895
5.626ValLeu: 5.626 ± 3.282
2.813ValMet: 2.813 ± 1.641
1.406ValAsn: 1.406 ± 0.895
5.626ValPro: 5.626 ± 1.64
4.219ValGln: 4.219 ± 2.684
2.813ValArg: 2.813 ± 1.641
5.626ValSer: 5.626 ± 2.54
1.406ValThr: 1.406 ± 0.895
2.813ValVal: 2.813 ± 0.662
2.813ValTrp: 2.813 ± 2.208
2.813ValTyr: 2.813 ± 1.641
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
4.219TrpAsp: 4.219 ± 1.214
4.219TrpGlu: 4.219 ± 1.586
0.0TrpPhe: 0.0 ± 0.0
1.406TrpGly: 1.406 ± 1.793
0.0TrpHis: 0.0 ± 0.0
1.406TrpIle: 1.406 ± 1.104
1.406TrpLys: 1.406 ± 1.104
1.406TrpLeu: 1.406 ± 1.104
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.406TrpPro: 1.406 ± 0.895
1.406TrpGln: 1.406 ± 1.104
1.406TrpArg: 1.406 ± 0.895
1.406TrpSer: 1.406 ± 1.104
5.626TrpThr: 5.626 ± 1.64
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.406TrpTyr: 1.406 ± 1.104
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.032TyrAla: 7.032 ± 4.919
0.0TyrCys: 0.0 ± 0.0
4.219TyrAsp: 4.219 ± 1.586
2.813TyrGlu: 2.813 ± 2.208
1.406TyrPhe: 1.406 ± 0.895
2.813TyrGly: 2.813 ± 1.789
0.0TyrHis: 0.0 ± 0.0
5.626TyrIle: 5.626 ± 1.64
4.219TyrLys: 4.219 ± 3.515
1.406TyrLeu: 1.406 ± 1.104
1.406TyrMet: 1.406 ± 1.104
4.219TyrAsn: 4.219 ± 3.318
1.406TyrPro: 1.406 ± 1.793
0.0TyrGln: 0.0 ± 0.0
4.219TyrArg: 4.219 ± 1.942
1.406TyrSer: 1.406 ± 1.793
0.0TyrThr: 0.0 ± 0.0
4.219TyrVal: 4.219 ± 1.122
2.813TyrTrp: 2.813 ± 3.585
4.219TyrTyr: 4.219 ± 1.942
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (712 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski