Amino acid dipepetide frequency for Landjia virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.562AlaAla: 1.562 ± 0.83
0.669AlaCys: 0.669 ± 0.279
2.232AlaAsp: 2.232 ± 0.538
1.339AlaGlu: 1.339 ± 0.493
1.562AlaPhe: 1.562 ± 0.701
1.785AlaGly: 1.785 ± 0.937
1.116AlaHis: 1.116 ± 0.472
4.017AlaIle: 4.017 ± 0.6
2.678AlaLys: 2.678 ± 0.903
4.017AlaLeu: 4.017 ± 0.888
1.339AlaMet: 1.339 ± 0.421
0.669AlaAsn: 0.669 ± 0.398
0.893AlaPro: 0.893 ± 0.679
1.562AlaGln: 1.562 ± 0.49
2.008AlaArg: 2.008 ± 0.773
2.008AlaSer: 2.008 ± 0.437
3.124AlaThr: 3.124 ± 1.012
1.785AlaVal: 1.785 ± 0.428
0.446AlaTrp: 0.446 ± 0.265
2.901AlaTyr: 2.901 ± 1.031
0.0AlaXaa: 0.0 ± 0.0
Cys
0.223CysAla: 0.223 ± 0.277
0.446CysCys: 0.446 ± 0.325
0.0CysAsp: 0.0 ± 0.0
1.116CysGlu: 1.116 ± 0.474
0.446CysPhe: 0.446 ± 0.265
0.893CysGly: 0.893 ± 0.469
0.893CysHis: 0.893 ± 0.33
0.893CysIle: 0.893 ± 0.442
0.893CysLys: 0.893 ± 0.369
1.562CysLeu: 1.562 ± 0.649
0.0CysMet: 0.0 ± 0.0
1.339CysAsn: 1.339 ± 0.752
1.339CysPro: 1.339 ± 0.765
1.339CysGln: 1.339 ± 0.501
0.893CysArg: 0.893 ± 0.53
1.785CysSer: 1.785 ± 0.478
0.669CysThr: 0.669 ± 0.307
0.446CysVal: 0.446 ± 0.294
0.446CysTrp: 0.446 ± 0.428
0.446CysTyr: 0.446 ± 0.294
0.0CysXaa: 0.0 ± 0.0
Asp
1.785AspAla: 1.785 ± 0.917
1.339AspCys: 1.339 ± 0.505
4.017AspAsp: 4.017 ± 1.335
3.794AspGlu: 3.794 ± 0.815
3.347AspPhe: 3.347 ± 1.438
3.124AspGly: 3.124 ± 0.788
1.785AspHis: 1.785 ± 0.674
4.017AspIle: 4.017 ± 0.965
4.017AspLys: 4.017 ± 0.881
7.364AspLeu: 7.364 ± 1.26
1.339AspMet: 1.339 ± 0.478
3.347AspAsn: 3.347 ± 0.478
3.124AspPro: 3.124 ± 0.673
1.785AspGln: 1.785 ± 0.511
1.785AspArg: 1.785 ± 0.428
2.232AspSer: 2.232 ± 0.532
1.785AspThr: 1.785 ± 0.402
3.124AspVal: 3.124 ± 0.753
1.562AspTrp: 1.562 ± 0.606
2.901AspTyr: 2.901 ± 0.689
0.0AspXaa: 0.0 ± 0.0
Glu
1.339GluAla: 1.339 ± 0.415
0.446GluCys: 0.446 ± 0.235
4.686GluAsp: 4.686 ± 0.787
3.571GluGlu: 3.571 ± 1.042
1.562GluPhe: 1.562 ± 0.748
3.571GluGly: 3.571 ± 0.804
1.116GluHis: 1.116 ± 0.399
3.794GluIle: 3.794 ± 1.737
4.017GluLys: 4.017 ± 0.938
5.133GluLeu: 5.133 ± 0.608
1.339GluMet: 1.339 ± 0.589
2.678GluAsn: 2.678 ± 1.179
2.678GluPro: 2.678 ± 0.779
2.232GluGln: 2.232 ± 0.706
1.339GluArg: 1.339 ± 0.394
4.686GluSer: 4.686 ± 0.987
2.678GluThr: 2.678 ± 0.556
2.232GluVal: 2.232 ± 0.712
2.232GluTrp: 2.232 ± 0.512
3.347GluTyr: 3.347 ± 0.671
0.0GluXaa: 0.0 ± 0.0
Phe
1.785PheAla: 1.785 ± 0.481
0.446PheCys: 0.446 ± 0.343
2.455PheAsp: 2.455 ± 1.028
2.008PheGlu: 2.008 ± 0.459
2.455PhePhe: 2.455 ± 0.696
2.232PheGly: 2.232 ± 0.686
0.669PheHis: 0.669 ± 0.355
2.232PheIle: 2.232 ± 0.72
4.017PheLys: 4.017 ± 1.35
5.579PheLeu: 5.579 ± 0.964
1.785PheMet: 1.785 ± 0.575
2.008PheAsn: 2.008 ± 0.796
2.008PhePro: 2.008 ± 0.429
1.562PheGln: 1.562 ± 0.591
2.008PheArg: 2.008 ± 0.611
4.017PheSer: 4.017 ± 0.891
1.785PheThr: 1.785 ± 0.749
2.232PheVal: 2.232 ± 0.831
0.446PheTrp: 0.446 ± 0.265
1.339PheTyr: 1.339 ± 0.55
0.0PheXaa: 0.0 ± 0.0
Gly
1.339GlyAla: 1.339 ± 0.379
0.446GlyCys: 0.446 ± 0.231
2.232GlyAsp: 2.232 ± 0.779
3.571GlyGlu: 3.571 ± 0.942
1.562GlyPhe: 1.562 ± 0.466
2.678GlyGly: 2.678 ± 0.702
1.116GlyHis: 1.116 ± 0.521
6.472GlyIle: 6.472 ± 1.015
6.025GlyLys: 6.025 ± 1.861
5.133GlyLeu: 5.133 ± 1.855
0.223GlyMet: 0.223 ± 0.133
2.008GlyAsn: 2.008 ± 0.684
1.562GlyPro: 1.562 ± 0.945
2.678GlyGln: 2.678 ± 0.734
2.008GlyArg: 2.008 ± 0.719
5.133GlySer: 5.133 ± 1.175
2.455GlyThr: 2.455 ± 0.894
2.678GlyVal: 2.678 ± 1.336
0.893GlyTrp: 0.893 ± 0.218
2.008GlyTyr: 2.008 ± 0.673
0.0GlyXaa: 0.0 ± 0.0
His
0.893HisAla: 0.893 ± 0.351
0.223HisCys: 0.223 ± 0.133
2.232HisAsp: 2.232 ± 0.696
0.223HisGlu: 0.223 ± 0.133
0.893HisPhe: 0.893 ± 0.362
1.562HisGly: 1.562 ± 0.811
2.232HisHis: 2.232 ± 0.479
3.794HisIle: 3.794 ± 0.982
0.893HisLys: 0.893 ± 0.53
3.794HisLeu: 3.794 ± 0.877
1.116HisMet: 1.116 ± 0.539
2.455HisAsn: 2.455 ± 0.72
1.785HisPro: 1.785 ± 0.615
0.446HisGln: 0.446 ± 0.265
1.339HisArg: 1.339 ± 0.796
1.339HisSer: 1.339 ± 0.353
1.116HisThr: 1.116 ± 0.416
1.116HisVal: 1.116 ± 0.349
0.446HisTrp: 0.446 ± 0.235
1.339HisTyr: 1.339 ± 0.844
0.0HisXaa: 0.0 ± 0.0
Ile
3.124IleAla: 3.124 ± 0.673
1.785IleCys: 1.785 ± 0.615
6.025IleAsp: 6.025 ± 1.196
5.356IleGlu: 5.356 ± 0.93
3.794IlePhe: 3.794 ± 0.89
4.91IleGly: 4.91 ± 0.968
2.455IleHis: 2.455 ± 0.97
9.15IleIle: 9.15 ± 1.954
5.802IleLys: 5.802 ± 1.005
7.811IleLeu: 7.811 ± 1.361
0.893IleMet: 0.893 ± 0.33
4.686IleAsn: 4.686 ± 1.132
2.455IlePro: 2.455 ± 0.467
2.232IleGln: 2.232 ± 0.726
5.802IleArg: 5.802 ± 0.756
5.579IleSer: 5.579 ± 0.822
3.571IleThr: 3.571 ± 1.614
4.24IleVal: 4.24 ± 0.831
1.562IleTrp: 1.562 ± 0.394
3.794IleTyr: 3.794 ± 1.029
0.0IleXaa: 0.0 ± 0.0
Lys
2.008LysAla: 2.008 ± 0.967
0.446LysCys: 0.446 ± 0.231
2.678LysAsp: 2.678 ± 0.563
4.24LysGlu: 4.24 ± 0.821
2.232LysPhe: 2.232 ± 0.637
4.463LysGly: 4.463 ± 1.285
1.785LysHis: 1.785 ± 0.452
5.579LysIle: 5.579 ± 1.509
6.249LysLys: 6.249 ± 1.372
7.364LysLeu: 7.364 ± 1.817
1.785LysMet: 1.785 ± 0.503
3.347LysAsn: 3.347 ± 0.722
2.455LysPro: 2.455 ± 0.895
1.785LysGln: 1.785 ± 0.641
4.686LysArg: 4.686 ± 1.05
6.025LysSer: 6.025 ± 0.914
2.901LysThr: 2.901 ± 0.834
6.472LysVal: 6.472 ± 0.6
1.785LysTrp: 1.785 ± 0.44
1.339LysTyr: 1.339 ± 0.404
0.0LysXaa: 0.0 ± 0.0
Leu
3.347LeuAla: 3.347 ± 1.088
2.232LeuCys: 2.232 ± 0.53
6.025LeuAsp: 6.025 ± 0.951
5.133LeuGlu: 5.133 ± 1.181
4.91LeuPhe: 4.91 ± 0.688
4.91LeuGly: 4.91 ± 1.469
2.678LeuHis: 2.678 ± 0.62
9.819LeuIle: 9.819 ± 2.413
7.364LeuLys: 7.364 ± 1.618
6.918LeuLeu: 6.918 ± 1.32
2.008LeuMet: 2.008 ± 0.575
7.364LeuAsn: 7.364 ± 0.933
3.794LeuPro: 3.794 ± 0.552
4.91LeuGln: 4.91 ± 1.632
3.794LeuArg: 3.794 ± 0.526
8.034LeuSer: 8.034 ± 1.244
5.579LeuThr: 5.579 ± 1.147
3.571LeuVal: 3.571 ± 0.801
1.562LeuTrp: 1.562 ± 0.622
3.124LeuTyr: 3.124 ± 0.721
0.0LeuXaa: 0.0 ± 0.0
Met
0.446MetAla: 0.446 ± 0.265
0.446MetCys: 0.446 ± 0.373
2.455MetAsp: 2.455 ± 1.334
2.232MetGlu: 2.232 ± 0.592
1.339MetPhe: 1.339 ± 0.586
0.669MetGly: 0.669 ± 0.482
0.223MetHis: 0.223 ± 0.277
2.008MetIle: 2.008 ± 0.693
2.232MetLys: 2.232 ± 0.932
2.678MetLeu: 2.678 ± 0.816
1.562MetMet: 1.562 ± 0.945
1.339MetAsn: 1.339 ± 0.565
0.893MetPro: 0.893 ± 0.796
0.223MetGln: 0.223 ± 0.133
0.446MetArg: 0.446 ± 0.554
2.008MetSer: 2.008 ± 0.788
2.008MetThr: 2.008 ± 0.495
1.562MetVal: 1.562 ± 0.531
0.446MetTrp: 0.446 ± 0.398
1.116MetTyr: 1.116 ± 0.749
0.0MetXaa: 0.0 ± 0.0
Asn
3.124AsnAla: 3.124 ± 0.858
1.339AsnCys: 1.339 ± 0.493
2.455AsnAsp: 2.455 ± 0.631
2.232AsnGlu: 2.232 ± 0.482
1.562AsnPhe: 1.562 ± 0.491
2.678AsnGly: 2.678 ± 0.924
2.901AsnHis: 2.901 ± 0.606
4.91AsnIle: 4.91 ± 1.24
4.017AsnLys: 4.017 ± 1.109
6.472AsnLeu: 6.472 ± 1.843
1.116AsnMet: 1.116 ± 0.538
6.249AsnAsn: 6.249 ± 1.307
3.347AsnPro: 3.347 ± 0.547
2.678AsnGln: 2.678 ± 0.7
1.339AsnArg: 1.339 ± 0.563
3.124AsnSer: 3.124 ± 0.803
3.347AsnThr: 3.347 ± 0.747
3.347AsnVal: 3.347 ± 0.696
1.562AsnTrp: 1.562 ± 0.468
3.794AsnTyr: 3.794 ± 1.145
0.0AsnXaa: 0.0 ± 0.0
Pro
0.446ProAla: 0.446 ± 0.265
0.223ProCys: 0.223 ± 0.245
3.347ProAsp: 3.347 ± 0.565
2.232ProGlu: 2.232 ± 0.897
1.339ProPhe: 1.339 ± 0.616
1.785ProGly: 1.785 ± 0.651
1.339ProHis: 1.339 ± 0.633
5.133ProIle: 5.133 ± 1.273
2.232ProLys: 2.232 ± 0.982
3.794ProLeu: 3.794 ± 1.162
1.785ProMet: 1.785 ± 0.657
2.232ProAsn: 2.232 ± 0.441
1.785ProPro: 1.785 ± 1.237
1.562ProGln: 1.562 ± 0.766
1.562ProArg: 1.562 ± 0.557
5.356ProSer: 5.356 ± 1.247
2.232ProThr: 2.232 ± 0.674
2.232ProVal: 2.232 ± 0.58
0.669ProTrp: 0.669 ± 0.324
2.678ProTyr: 2.678 ± 0.889
0.0ProXaa: 0.0 ± 0.0
Gln
1.562GlnAla: 1.562 ± 0.327
0.669GlnCys: 0.669 ± 0.331
0.893GlnAsp: 0.893 ± 0.638
2.901GlnGlu: 2.901 ± 0.827
1.785GlnPhe: 1.785 ± 0.488
0.893GlnGly: 0.893 ± 0.362
1.116GlnHis: 1.116 ± 0.456
2.455GlnIle: 2.455 ± 0.42
2.008GlnLys: 2.008 ± 0.408
4.24GlnLeu: 4.24 ± 0.734
0.669GlnMet: 0.669 ± 0.487
1.785GlnAsn: 1.785 ± 0.502
0.893GlnPro: 0.893 ± 0.557
1.339GlnGln: 1.339 ± 0.538
1.785GlnArg: 1.785 ± 0.409
4.017GlnSer: 4.017 ± 0.603
2.008GlnThr: 2.008 ± 0.504
2.008GlnVal: 2.008 ± 0.926
0.446GlnTrp: 0.446 ± 0.235
1.785GlnTyr: 1.785 ± 0.538
0.0GlnXaa: 0.0 ± 0.0
Arg
2.232ArgAla: 2.232 ± 0.586
0.669ArgCys: 0.669 ± 0.335
1.562ArgAsp: 1.562 ± 0.33
2.901ArgGlu: 2.901 ± 0.861
3.794ArgPhe: 3.794 ± 0.648
2.008ArgGly: 2.008 ± 0.761
0.893ArgHis: 0.893 ± 0.42
2.901ArgIle: 2.901 ± 0.79
1.562ArgLys: 1.562 ± 0.417
2.678ArgLeu: 2.678 ± 0.952
1.785ArgMet: 1.785 ± 0.536
4.24ArgAsn: 4.24 ± 0.634
2.232ArgPro: 2.232 ± 0.471
1.785ArgGln: 1.785 ± 0.617
2.455ArgArg: 2.455 ± 0.728
3.794ArgSer: 3.794 ± 0.868
2.678ArgThr: 2.678 ± 0.84
2.232ArgVal: 2.232 ± 0.683
0.893ArgTrp: 0.893 ± 0.522
1.339ArgTyr: 1.339 ± 0.665
0.0ArgXaa: 0.0 ± 0.0
Ser
4.91SerAla: 4.91 ± 1.008
1.339SerCys: 1.339 ± 0.465
5.133SerAsp: 5.133 ± 1.024
3.124SerGlu: 3.124 ± 0.628
2.678SerPhe: 2.678 ± 0.843
3.794SerGly: 3.794 ± 1.046
2.455SerHis: 2.455 ± 1.255
6.472SerIle: 6.472 ± 0.753
4.463SerLys: 4.463 ± 0.683
9.819SerLeu: 9.819 ± 1.044
0.893SerMet: 0.893 ± 0.553
4.91SerAsn: 4.91 ± 0.739
4.463SerPro: 4.463 ± 0.673
2.455SerGln: 2.455 ± 0.634
3.794SerArg: 3.794 ± 0.53
6.918SerSer: 6.918 ± 1.921
4.24SerThr: 4.24 ± 0.876
4.463SerVal: 4.463 ± 1.416
2.232SerTrp: 2.232 ± 0.557
2.455SerTyr: 2.455 ± 0.562
0.0SerXaa: 0.0 ± 0.0
Thr
1.116ThrAla: 1.116 ± 0.467
0.893ThrCys: 0.893 ± 0.362
2.232ThrAsp: 2.232 ± 0.43
3.124ThrGlu: 3.124 ± 0.933
2.008ThrPhe: 2.008 ± 0.809
3.347ThrGly: 3.347 ± 0.683
1.116ThrHis: 1.116 ± 0.494
4.686ThrIle: 4.686 ± 0.968
4.686ThrLys: 4.686 ± 0.652
2.232ThrLeu: 2.232 ± 1.175
1.562ThrMet: 1.562 ± 0.51
4.24ThrAsn: 4.24 ± 0.707
1.562ThrPro: 1.562 ± 0.957
1.785ThrGln: 1.785 ± 0.551
2.455ThrArg: 2.455 ± 0.596
3.571ThrSer: 3.571 ± 1.01
3.124ThrThr: 3.124 ± 0.694
2.232ThrVal: 2.232 ± 0.546
1.562ThrTrp: 1.562 ± 0.355
2.008ThrTyr: 2.008 ± 0.382
0.0ThrXaa: 0.0 ± 0.0
Val
2.232ValAla: 2.232 ± 0.576
1.339ValCys: 1.339 ± 0.637
2.232ValAsp: 2.232 ± 0.495
2.008ValGlu: 2.008 ± 0.637
2.008ValPhe: 2.008 ± 0.528
2.232ValGly: 2.232 ± 0.471
1.116ValHis: 1.116 ± 0.54
2.901ValIle: 2.901 ± 0.964
2.008ValLys: 2.008 ± 0.411
4.686ValLeu: 4.686 ± 0.744
2.455ValMet: 2.455 ± 1.11
2.901ValAsn: 2.901 ± 0.625
4.017ValPro: 4.017 ± 0.491
2.008ValGln: 2.008 ± 0.883
2.008ValArg: 2.008 ± 0.601
6.472ValSer: 6.472 ± 1.074
1.785ValThr: 1.785 ± 0.575
2.678ValVal: 2.678 ± 0.655
1.116ValTrp: 1.116 ± 0.499
2.901ValTyr: 2.901 ± 1.166
0.0ValXaa: 0.0 ± 0.0
Trp
1.339TrpAla: 1.339 ± 0.527
0.223TrpCys: 0.223 ± 0.277
1.562TrpAsp: 1.562 ± 0.415
2.008TrpGlu: 2.008 ± 0.869
1.562TrpPhe: 1.562 ± 0.507
2.455TrpGly: 2.455 ± 0.656
0.223TrpHis: 0.223 ± 0.133
1.116TrpIle: 1.116 ± 0.512
1.116TrpLys: 1.116 ± 0.663
1.562TrpLeu: 1.562 ± 0.836
1.339TrpMet: 1.339 ± 0.976
1.116TrpAsn: 1.116 ± 0.663
0.446TrpPro: 0.446 ± 0.294
0.0TrpGln: 0.0 ± 0.0
1.339TrpArg: 1.339 ± 0.52
1.785TrpSer: 1.785 ± 0.411
0.446TrpThr: 0.446 ± 0.265
0.446TrpVal: 0.446 ± 0.333
0.446TrpTrp: 0.446 ± 0.528
0.893TrpTyr: 0.893 ± 0.348
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.901TyrAla: 2.901 ± 0.799
0.446TyrCys: 0.446 ± 0.235
3.124TyrAsp: 3.124 ± 1.009
1.562TyrGlu: 1.562 ± 0.517
2.232TyrPhe: 2.232 ± 0.792
2.232TyrGly: 2.232 ± 0.617
2.008TyrHis: 2.008 ± 0.759
2.678TyrIle: 2.678 ± 1.279
3.347TyrLys: 3.347 ± 0.685
4.24TyrLeu: 4.24 ± 1.211
1.116TyrMet: 1.116 ± 0.688
2.678TyrAsn: 2.678 ± 0.889
2.232TyrPro: 2.232 ± 0.748
0.893TyrGln: 0.893 ± 0.458
1.785TyrArg: 1.785 ± 0.964
3.124TyrSer: 3.124 ± 0.939
2.008TyrThr: 2.008 ± 0.815
2.008TyrVal: 2.008 ± 0.414
0.893TyrTrp: 0.893 ± 0.563
1.339TyrTyr: 1.339 ± 0.659
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (4482 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski