Amino acid dipepetide frequency for Saguaro cactus virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.986AlaAla: 9.986 ± 3.2
1.427AlaCys: 1.427 ± 0.696
2.378AlaAsp: 2.378 ± 1.143
3.804AlaGlu: 3.804 ± 1.125
3.804AlaPhe: 3.804 ± 0.946
6.182AlaGly: 6.182 ± 0.801
0.951AlaHis: 0.951 ± 0.389
3.329AlaIle: 3.329 ± 0.949
2.853AlaLys: 2.853 ± 1.561
4.755AlaLeu: 4.755 ± 0.667
2.853AlaMet: 2.853 ± 1.438
1.902AlaAsn: 1.902 ± 0.522
5.706AlaPro: 5.706 ± 0.769
4.28AlaGln: 4.28 ± 0.798
7.608AlaArg: 7.608 ± 1.055
3.804AlaSer: 3.804 ± 0.901
5.231AlaThr: 5.231 ± 2.413
4.28AlaVal: 4.28 ± 1.395
2.853AlaTrp: 2.853 ± 0.706
3.804AlaTyr: 3.804 ± 1.044
0.0AlaXaa: 0.0 ± 0.0
Cys
0.951CysAla: 0.951 ± 1.469
0.0CysCys: 0.0 ± 0.0
0.476CysAsp: 0.476 ± 0.422
1.427CysGlu: 1.427 ± 0.345
0.0CysPhe: 0.0 ± 0.0
2.378CysGly: 2.378 ± 1.462
1.902CysHis: 1.902 ± 0.958
1.902CysIle: 1.902 ± 0.778
0.476CysLys: 0.476 ± 0.767
2.378CysLeu: 2.378 ± 0.623
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.427CysPro: 1.427 ± 0.954
1.427CysGln: 1.427 ± 0.345
3.329CysArg: 3.329 ± 0.834
0.951CysSer: 0.951 ± 0.843
0.951CysThr: 0.951 ± 0.433
3.329CysVal: 3.329 ± 1.228
0.951CysTrp: 0.951 ± 0.624
0.951CysTyr: 0.951 ± 0.389
0.0CysXaa: 0.0 ± 0.0
Asp
4.755AspAla: 4.755 ± 0.813
2.853AspCys: 2.853 ± 0.786
4.28AspAsp: 4.28 ± 1.243
2.853AspGlu: 2.853 ± 0.923
1.427AspPhe: 1.427 ± 0.345
3.329AspGly: 3.329 ± 0.954
2.378AspHis: 2.378 ± 0.941
1.902AspIle: 1.902 ± 0.64
4.28AspLys: 4.28 ± 1.076
4.28AspLeu: 4.28 ± 1.373
1.902AspMet: 1.902 ± 0.778
0.951AspAsn: 0.951 ± 0.923
6.182AspPro: 6.182 ± 1.543
0.951AspGln: 0.951 ± 0.389
2.853AspArg: 2.853 ± 1.167
2.378AspSer: 2.378 ± 1.059
1.902AspThr: 1.902 ± 0.898
2.853AspVal: 2.853 ± 0.708
0.0AspTrp: 0.0 ± 0.0
0.476AspTyr: 0.476 ± 0.422
0.0AspXaa: 0.0 ± 0.0
Glu
3.329GluAla: 3.329 ± 0.52
0.476GluCys: 0.476 ± 0.422
2.853GluAsp: 2.853 ± 0.923
2.853GluGlu: 2.853 ± 0.786
1.902GluPhe: 1.902 ± 0.522
1.427GluGly: 1.427 ± 0.638
2.853GluHis: 2.853 ± 0.786
3.804GluIle: 3.804 ± 1.125
3.804GluLys: 3.804 ± 1.125
7.608GluLeu: 7.608 ± 1.648
0.476GluMet: 0.476 ± 0.943
0.476GluAsn: 0.476 ± 0.422
2.853GluPro: 2.853 ± 1.167
1.427GluGln: 1.427 ± 0.696
2.853GluArg: 2.853 ± 0.786
0.951GluSer: 0.951 ± 0.843
2.378GluThr: 2.378 ± 0.367
5.231GluVal: 5.231 ± 1.22
0.951GluTrp: 0.951 ± 0.389
0.951GluTyr: 0.951 ± 0.843
0.0GluXaa: 0.0 ± 0.0
Phe
0.951PheAla: 0.951 ± 0.389
2.378PheCys: 2.378 ± 0.828
2.853PheAsp: 2.853 ± 1.167
1.427PheGlu: 1.427 ± 0.345
0.0PhePhe: 0.0 ± 0.0
3.329PheGly: 3.329 ± 0.52
0.951PheHis: 0.951 ± 0.389
0.951PheIle: 0.951 ± 0.923
2.853PheLys: 2.853 ± 1.167
4.28PheLeu: 4.28 ± 1.268
0.476PheMet: 0.476 ± 0.597
1.902PheAsn: 1.902 ± 0.64
0.951PhePro: 0.951 ± 0.843
0.951PheGln: 0.951 ± 0.389
0.0PheArg: 0.0 ± 0.0
2.853PheSer: 2.853 ± 0.728
4.28PheThr: 4.28 ± 0.798
1.902PheVal: 1.902 ± 0.855
0.951PheTrp: 0.951 ± 0.389
1.902PheTyr: 1.902 ± 0.778
0.0PheXaa: 0.0 ± 0.0
Gly
2.853GlyAla: 2.853 ± 0.594
1.427GlyCys: 1.427 ± 0.611
3.804GlyAsp: 3.804 ± 1.556
2.853GlyGlu: 2.853 ± 0.594
3.804GlyPhe: 3.804 ± 1.125
5.706GlyGly: 5.706 ± 1.383
0.951GlyHis: 0.951 ± 0.389
1.902GlyIle: 1.902 ± 1.256
4.28GlyLys: 4.28 ± 1.911
15.216GlyLeu: 15.216 ± 1.857
0.0GlyMet: 0.0 ± 0.0
2.378GlyAsn: 2.378 ± 1.124
3.329GlyPro: 3.329 ± 0.751
1.427GlyGln: 1.427 ± 0.611
4.755GlyArg: 4.755 ± 1.508
1.902GlySer: 1.902 ± 1.256
5.231GlyThr: 5.231 ± 0.872
3.329GlyVal: 3.329 ± 1.044
1.427GlyTrp: 1.427 ± 0.55
0.951GlyTyr: 0.951 ± 0.389
0.0GlyXaa: 0.0 ± 0.0
His
2.853HisAla: 2.853 ± 1.438
0.0HisCys: 0.0 ± 0.0
0.951HisAsp: 0.951 ± 0.389
0.0HisGlu: 0.0 ± 0.0
1.902HisPhe: 1.902 ± 0.522
0.476HisGly: 0.476 ± 1.076
1.902HisHis: 1.902 ± 0.522
4.28HisIle: 4.28 ± 0.95
0.951HisLys: 0.951 ± 0.479
2.378HisLeu: 2.378 ± 0.655
0.951HisMet: 0.951 ± 0.389
1.902HisAsn: 1.902 ± 0.778
0.476HisPro: 0.476 ± 0.328
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.902HisSer: 1.902 ± 0.522
2.853HisThr: 2.853 ± 0.923
3.329HisVal: 3.329 ± 0.52
0.476HisTrp: 0.476 ± 0.422
0.476HisTyr: 0.476 ± 0.767
0.0HisXaa: 0.0 ± 0.0
Ile
7.133IleAla: 7.133 ± 1.583
1.902IleCys: 1.902 ± 0.778
0.0IleAsp: 0.0 ± 0.0
2.853IleGlu: 2.853 ± 0.594
0.951IlePhe: 0.951 ± 0.389
4.28IleGly: 4.28 ± 1.057
0.0IleHis: 0.0 ± 0.0
1.427IleIle: 1.427 ± 0.696
0.476IleLys: 0.476 ± 0.422
5.231IleLeu: 5.231 ± 1.049
0.476IleMet: 0.476 ± 1.076
0.951IleAsn: 0.951 ± 0.389
2.378IlePro: 2.378 ± 1.059
0.951IleGln: 0.951 ± 0.389
3.804IleArg: 3.804 ± 2.252
4.28IleSer: 4.28 ± 1.651
2.853IleThr: 2.853 ± 0.616
5.231IleVal: 5.231 ± 2.256
0.951IleTrp: 0.951 ± 0.389
1.902IleTyr: 1.902 ± 0.778
0.0IleXaa: 0.0 ± 0.0
Lys
4.28LysAla: 4.28 ± 1.313
2.853LysCys: 2.853 ± 1.099
1.902LysAsp: 1.902 ± 0.64
3.804LysGlu: 3.804 ± 1.044
1.902LysPhe: 1.902 ± 0.522
2.378LysGly: 2.378 ± 0.602
1.427LysHis: 1.427 ± 0.696
3.804LysIle: 3.804 ± 1.044
0.951LysLys: 0.951 ± 0.389
3.329LysLeu: 3.329 ± 0.52
0.476LysMet: 0.476 ± 0.504
1.427LysAsn: 1.427 ± 0.696
2.378LysPro: 2.378 ± 0.825
0.951LysGln: 0.951 ± 0.787
2.853LysArg: 2.853 ± 0.708
0.951LysSer: 0.951 ± 0.843
5.706LysThr: 5.706 ± 1.227
6.182LysVal: 6.182 ± 1.175
0.951LysTrp: 0.951 ± 0.389
0.951LysTyr: 0.951 ± 0.843
0.476LysXaa: 0.476 ± 0.328
Leu
6.182LeuAla: 6.182 ± 0.992
1.427LeuCys: 1.427 ± 1.639
5.706LeuAsp: 5.706 ± 1.758
4.755LeuGlu: 4.755 ± 1.053
2.378LeuPhe: 2.378 ± 0.367
2.853LeuGly: 2.853 ± 1.101
3.804LeuHis: 3.804 ± 1.044
6.182LeuIle: 6.182 ± 1.605
4.755LeuLys: 4.755 ± 1.489
8.559LeuLeu: 8.559 ± 5.491
3.329LeuMet: 3.329 ± 1.354
2.378LeuAsn: 2.378 ± 0.367
4.755LeuPro: 4.755 ± 1.652
5.706LeuGln: 5.706 ± 1.018
8.084LeuArg: 8.084 ± 1.487
9.51LeuSer: 9.51 ± 2.807
5.231LeuThr: 5.231 ± 2.413
10.937LeuVal: 10.937 ± 2.138
1.902LeuTrp: 1.902 ± 0.958
1.902LeuTyr: 1.902 ± 0.541
0.0LeuXaa: 0.0 ± 0.0
Met
2.378MetAla: 2.378 ± 0.367
0.0MetCys: 0.0 ± 0.0
0.951MetAsp: 0.951 ± 0.787
0.0MetGlu: 0.0 ± 0.0
0.476MetPhe: 0.476 ± 1.076
1.902MetGly: 1.902 ± 0.995
0.0MetHis: 0.0 ± 0.0
0.951MetIle: 0.951 ± 0.389
1.902MetLys: 1.902 ± 0.522
0.951MetLeu: 0.951 ± 1.021
0.0MetMet: 0.0 ± 0.0
0.951MetAsn: 0.951 ± 0.389
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.853MetSer: 2.853 ± 1.167
0.951MetThr: 0.951 ± 1.17
3.804MetVal: 3.804 ± 1.12
0.0MetTrp: 0.0 ± 0.0
0.951MetTyr: 0.951 ± 0.389
0.0MetXaa: 0.0 ± 0.0
Asn
4.755AsnAla: 4.755 ± 1.945
0.951AsnCys: 0.951 ± 0.389
0.951AsnAsp: 0.951 ± 0.843
0.951AsnGlu: 0.951 ± 0.479
0.951AsnPhe: 0.951 ± 0.787
1.902AsnGly: 1.902 ± 0.898
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
1.902AsnLys: 1.902 ± 0.735
2.378AsnLeu: 2.378 ± 0.982
0.476AsnMet: 0.476 ± 0.328
2.853AsnAsn: 2.853 ± 1.207
1.902AsnPro: 1.902 ± 0.541
1.427AsnGln: 1.427 ± 1.214
2.853AsnArg: 2.853 ± 0.45
2.378AsnSer: 2.378 ± 0.655
0.951AsnThr: 0.951 ± 0.389
1.427AsnVal: 1.427 ± 0.345
0.476AsnTrp: 0.476 ± 0.617
1.427AsnTyr: 1.427 ± 0.954
0.0AsnXaa: 0.0 ± 0.0
Pro
5.706ProAla: 5.706 ± 0.942
2.378ProCys: 2.378 ± 0.602
4.28ProAsp: 4.28 ± 0.841
2.853ProGlu: 2.853 ± 0.786
0.0ProPhe: 0.0 ± 0.0
1.902ProGly: 1.902 ± 1.247
0.0ProHis: 0.0 ± 0.0
1.902ProIle: 1.902 ± 0.778
1.902ProLys: 1.902 ± 0.665
4.28ProLeu: 4.28 ± 1.278
0.476ProMet: 0.476 ± 1.184
0.951ProAsn: 0.951 ± 0.757
1.427ProPro: 1.427 ± 0.8
0.476ProGln: 0.476 ± 0.422
6.182ProArg: 6.182 ± 1.094
2.378ProSer: 2.378 ± 1.764
2.378ProThr: 2.378 ± 1.23
6.182ProVal: 6.182 ± 0.948
0.951ProTrp: 0.951 ± 0.479
0.476ProTyr: 0.476 ± 0.422
0.0ProXaa: 0.0 ± 0.0
Gln
2.378GlnAla: 2.378 ± 0.891
1.427GlnCys: 1.427 ± 0.611
0.0GlnAsp: 0.0 ± 0.0
2.853GlnGlu: 2.853 ± 1.167
2.378GlnPhe: 2.378 ± 0.602
1.902GlnGly: 1.902 ± 0.665
1.427GlnHis: 1.427 ± 0.696
0.476GlnIle: 0.476 ± 0.767
1.427GlnLys: 1.427 ± 0.345
6.182GlnLeu: 6.182 ± 1.015
0.951GlnMet: 0.951 ± 0.389
0.476GlnAsn: 0.476 ± 0.422
1.427GlnPro: 1.427 ± 0.345
4.28GlnGln: 4.28 ± 0.841
1.427GlnArg: 1.427 ± 0.55
0.0GlnSer: 0.0 ± 0.0
0.476GlnThr: 0.476 ± 0.422
1.902GlnVal: 1.902 ± 0.778
0.951GlnTrp: 0.951 ± 0.389
0.951GlnTyr: 0.951 ± 0.389
0.0GlnXaa: 0.0 ± 0.0
Arg
3.804ArgAla: 3.804 ± 0.548
0.0ArgCys: 0.0 ± 0.0
5.231ArgAsp: 5.231 ± 0.983
2.853ArgGlu: 2.853 ± 0.923
4.28ArgPhe: 4.28 ± 0.902
6.657ArgGly: 6.657 ± 1.042
0.951ArgHis: 0.951 ± 0.479
4.28ArgIle: 4.28 ± 0.921
1.427ArgLys: 1.427 ± 0.616
6.657ArgLeu: 6.657 ± 0.851
2.378ArgMet: 2.378 ± 0.831
3.329ArgAsn: 3.329 ± 1.228
2.853ArgPro: 2.853 ± 0.594
0.476ArgGln: 0.476 ± 0.422
6.657ArgArg: 6.657 ± 2.242
3.804ArgSer: 3.804 ± 0.954
6.182ArgThr: 6.182 ± 1.297
6.657ArgVal: 6.657 ± 0.916
2.378ArgTrp: 2.378 ± 0.975
4.28ArgTyr: 4.28 ± 0.916
0.476ArgXaa: 0.476 ± 1.076
Ser
4.755SerAla: 4.755 ± 0.759
1.427SerCys: 1.427 ± 1.639
3.804SerAsp: 3.804 ± 2.078
1.902SerGlu: 1.902 ± 0.522
3.804SerPhe: 3.804 ± 0.51
3.804SerGly: 3.804 ± 0.865
3.329SerHis: 3.329 ± 0.52
4.755SerIle: 4.755 ± 1.088
2.853SerLys: 2.853 ± 1.479
5.706SerLeu: 5.706 ± 1.418
1.427SerMet: 1.427 ± 0.345
1.902SerAsn: 1.902 ± 0.954
2.853SerPro: 2.853 ± 1.101
0.951SerGln: 0.951 ± 0.843
0.951SerArg: 0.951 ± 0.389
2.378SerSer: 2.378 ± 2.033
3.329SerThr: 3.329 ± 2.731
2.378SerVal: 2.378 ± 0.367
0.951SerTrp: 0.951 ± 0.389
1.427SerTyr: 1.427 ± 0.586
0.0SerXaa: 0.0 ± 0.0
Thr
5.706ThrAla: 5.706 ± 1.194
1.427ThrCys: 1.427 ± 0.345
1.427ThrAsp: 1.427 ± 0.55
2.853ThrGlu: 2.853 ± 0.708
2.853ThrPhe: 2.853 ± 0.728
3.804ThrGly: 3.804 ± 0.865
0.476ThrHis: 0.476 ± 0.328
2.853ThrIle: 2.853 ± 2.339
6.657ThrLys: 6.657 ± 1.256
3.804ThrLeu: 3.804 ± 1.871
0.0ThrMet: 0.0 ± 0.0
1.902ThrAsn: 1.902 ± 0.844
2.378ThrPro: 2.378 ± 1.074
0.476ThrGln: 0.476 ± 0.422
6.657ThrArg: 6.657 ± 1.562
2.378ThrSer: 2.378 ± 2.108
4.755ThrThr: 4.755 ± 1.123
5.706ThrVal: 5.706 ± 1.194
1.427ThrTrp: 1.427 ± 0.345
1.902ThrTyr: 1.902 ± 0.855
0.0ThrXaa: 0.0 ± 0.0
Val
6.657ValAla: 6.657 ± 0.868
2.378ValCys: 2.378 ± 0.844
8.559ValAsp: 8.559 ± 1.394
3.804ValGlu: 3.804 ± 1.12
1.902ValPhe: 1.902 ± 0.541
8.559ValGly: 8.559 ± 1.326
1.902ValHis: 1.902 ± 0.64
2.378ValIle: 2.378 ± 0.975
4.28ValLys: 4.28 ± 1.049
7.608ValLeu: 7.608 ± 1.53
1.902ValMet: 1.902 ± 0.778
1.427ValAsn: 1.427 ± 0.345
4.28ValPro: 4.28 ± 1.017
2.378ValGln: 2.378 ± 0.889
9.986ValArg: 9.986 ± 1.171
7.133ValSer: 7.133 ± 1.454
1.427ValThr: 1.427 ± 0.8
6.657ValVal: 6.657 ± 1.493
0.951ValTrp: 0.951 ± 0.757
3.329ValTyr: 3.329 ± 0.954
0.0ValXaa: 0.0 ± 0.0
Trp
0.951TrpAla: 0.951 ± 0.843
0.0TrpCys: 0.0 ± 0.0
0.951TrpAsp: 0.951 ± 0.389
1.427TrpGlu: 1.427 ± 0.345
1.427TrpPhe: 1.427 ± 0.345
2.378TrpGly: 2.378 ± 0.623
0.476TrpHis: 0.476 ± 0.767
0.951TrpIle: 0.951 ± 0.389
0.951TrpLys: 0.951 ± 0.389
1.902TrpLeu: 1.902 ± 0.541
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.902TrpGln: 1.902 ± 0.522
0.951TrpArg: 0.951 ± 0.757
0.0TrpSer: 0.0 ± 0.0
0.951TrpThr: 0.951 ± 0.389
4.28TrpVal: 4.28 ± 1.006
1.902TrpTrp: 1.902 ± 0.958
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.427TyrAla: 1.427 ± 0.345
0.476TyrCys: 0.476 ± 0.422
1.427TyrAsp: 1.427 ± 0.611
3.329TyrGlu: 3.329 ± 0.52
0.0TyrPhe: 0.0 ± 0.0
1.902TyrGly: 1.902 ± 0.665
2.378TyrHis: 2.378 ± 1.057
0.0TyrIle: 0.0 ± 0.0
0.951TyrLys: 0.951 ± 0.389
2.853TyrLeu: 2.853 ± 0.736
0.0TyrMet: 0.0 ± 0.0
2.853TyrAsn: 2.853 ± 0.869
0.0TyrPro: 0.0 ± 0.0
2.853TyrGln: 2.853 ± 1.167
3.804TyrArg: 3.804 ± 0.901
1.902TyrSer: 1.902 ± 1.287
1.427TyrThr: 1.427 ± 1.265
1.902TyrVal: 1.902 ± 0.522
0.0TyrTrp: 0.0 ± 0.0
1.427TyrTyr: 1.427 ± 0.954
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.476XaaGly: 0.476 ± 0.328
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.476XaaTyr: 0.476 ± 1.076
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2104 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski