Amino acid dipepetide frequency for Citrus tristeza virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.314AlaAla: 5.314 ± 1.036
1.162AlaCys: 1.162 ± 0.571
3.653AlaAsp: 3.653 ± 1.073
2.823AlaGlu: 2.823 ± 0.749
2.491AlaPhe: 2.491 ± 0.597
4.151AlaGly: 4.151 ± 0.641
0.996AlaHis: 0.996 ± 0.462
2.657AlaIle: 2.657 ± 0.945
3.653AlaLys: 3.653 ± 0.793
6.476AlaLeu: 6.476 ± 0.934
1.162AlaMet: 1.162 ± 0.348
1.328AlaAsn: 1.328 ± 0.622
1.827AlaPro: 1.827 ± 0.747
0.332AlaGln: 0.332 ± 0.218
4.65AlaArg: 4.65 ± 1.065
5.646AlaSer: 5.646 ± 1.015
3.321AlaThr: 3.321 ± 0.706
6.642AlaVal: 6.642 ± 0.748
0.332AlaTrp: 0.332 ± 0.2
2.325AlaTyr: 2.325 ± 0.544
0.0AlaXaa: 0.0 ± 0.0
Cys
0.996CysAla: 0.996 ± 0.473
0.83CysCys: 0.83 ± 0.584
1.328CysAsp: 1.328 ± 0.433
0.996CysGlu: 0.996 ± 0.322
1.661CysPhe: 1.661 ± 0.697
1.162CysGly: 1.162 ± 0.459
0.166CysHis: 0.166 ± 0.1
0.996CysIle: 0.996 ± 0.318
1.162CysLys: 1.162 ± 0.391
2.657CysLeu: 2.657 ± 0.628
0.498CysMet: 0.498 ± 0.351
0.498CysAsn: 0.498 ± 0.378
0.664CysPro: 0.664 ± 0.401
0.332CysGln: 0.332 ± 0.218
1.495CysArg: 1.495 ± 0.744
2.491CysSer: 2.491 ± 0.484
1.328CysThr: 1.328 ± 0.922
2.491CysVal: 2.491 ± 0.532
0.0CysTrp: 0.0 ± 0.0
1.495CysTyr: 1.495 ± 0.618
0.0CysXaa: 0.0 ± 0.0
Asp
3.653AspAla: 3.653 ± 0.619
1.162AspCys: 1.162 ± 0.449
5.314AspAsp: 5.314 ± 1.203
2.823AspGlu: 2.823 ± 0.763
2.989AspPhe: 2.989 ± 1.702
3.653AspGly: 3.653 ± 0.87
0.664AspHis: 0.664 ± 0.277
3.155AspIle: 3.155 ± 0.719
2.989AspLys: 2.989 ± 0.923
6.476AspLeu: 6.476 ± 1.115
1.162AspMet: 1.162 ± 0.43
2.657AspAsn: 2.657 ± 1.509
2.159AspPro: 2.159 ± 0.854
0.664AspGln: 0.664 ± 0.25
2.823AspArg: 2.823 ± 1.656
5.148AspSer: 5.148 ± 1.131
2.823AspThr: 2.823 ± 0.775
6.808AspVal: 6.808 ± 0.986
0.498AspTrp: 0.498 ± 0.3
1.993AspTyr: 1.993 ± 0.594
0.0AspXaa: 0.0 ± 0.0
Glu
2.491GluAla: 2.491 ± 0.413
0.83GluCys: 0.83 ± 0.371
2.159GluAsp: 2.159 ± 0.664
2.823GluGlu: 2.823 ± 0.896
3.321GluPhe: 3.321 ± 0.742
1.993GluGly: 1.993 ± 0.944
1.495GluHis: 1.495 ± 0.64
2.491GluIle: 2.491 ± 0.42
2.823GluLys: 2.823 ± 0.551
4.982GluLeu: 4.982 ± 0.864
1.328GluMet: 1.328 ± 0.682
1.661GluAsn: 1.661 ± 0.767
1.661GluPro: 1.661 ± 0.548
0.83GluGln: 0.83 ± 0.269
4.65GluArg: 4.65 ± 1.386
4.484GluSer: 4.484 ± 0.936
2.823GluThr: 2.823 ± 0.611
3.653GluVal: 3.653 ± 1.228
0.498GluTrp: 0.498 ± 0.3
2.657GluTyr: 2.657 ± 0.568
0.0GluXaa: 0.0 ± 0.0
Phe
2.823PheAla: 2.823 ± 0.695
1.162PheCys: 1.162 ± 0.394
4.318PheAsp: 4.318 ± 0.814
2.325PheGlu: 2.325 ± 0.616
2.159PhePhe: 2.159 ± 0.671
3.321PheGly: 3.321 ± 0.863
0.83PheHis: 0.83 ± 0.361
2.657PheIle: 2.657 ± 0.969
1.827PheLys: 1.827 ± 1.007
4.484PheLeu: 4.484 ± 1.262
0.664PheMet: 0.664 ± 0.253
2.989PheAsn: 2.989 ± 1.054
2.823PhePro: 2.823 ± 1.123
0.498PheGln: 0.498 ± 0.243
3.985PheArg: 3.985 ± 1.005
6.144PheSer: 6.144 ± 1.394
3.487PheThr: 3.487 ± 0.876
5.646PheVal: 5.646 ± 0.741
0.166PheTrp: 0.166 ± 0.1
1.661PheTyr: 1.661 ± 0.677
0.0PheXaa: 0.0 ± 0.0
Gly
2.491GlyAla: 2.491 ± 0.74
1.827GlyCys: 1.827 ± 0.437
2.325GlyAsp: 2.325 ± 1.003
4.484GlyGlu: 4.484 ± 0.81
3.487GlyPhe: 3.487 ± 0.944
3.819GlyGly: 3.819 ± 0.945
0.664GlyHis: 0.664 ± 0.284
1.495GlyIle: 1.495 ± 0.742
2.325GlyLys: 2.325 ± 0.999
4.484GlyLeu: 4.484 ± 0.525
1.328GlyMet: 1.328 ± 0.827
2.657GlyAsn: 2.657 ± 0.623
0.664GlyPro: 0.664 ± 0.314
1.495GlyGln: 1.495 ± 0.828
4.318GlyArg: 4.318 ± 1.095
6.144GlySer: 6.144 ± 1.466
4.816GlyThr: 4.816 ± 0.889
4.484GlyVal: 4.484 ± 0.843
0.498GlyTrp: 0.498 ± 0.355
2.989GlyTyr: 2.989 ± 1.714
0.0GlyXaa: 0.0 ± 0.0
His
1.328HisAla: 1.328 ± 0.403
0.664HisCys: 0.664 ± 0.253
0.498HisAsp: 0.498 ± 0.576
0.996HisGlu: 0.996 ± 0.349
0.996HisPhe: 0.996 ± 0.46
0.664HisGly: 0.664 ± 0.442
1.162HisHis: 1.162 ± 0.527
0.332HisIle: 0.332 ± 0.195
0.996HisLys: 0.996 ± 0.73
2.159HisLeu: 2.159 ± 1.227
0.498HisMet: 0.498 ± 0.483
0.0HisAsn: 0.0 ± 0.0
1.328HisPro: 1.328 ± 0.383
0.332HisGln: 0.332 ± 0.249
1.993HisArg: 1.993 ± 1.04
1.993HisSer: 1.993 ± 0.71
0.83HisThr: 0.83 ± 0.281
2.491HisVal: 2.491 ± 0.784
0.0HisTrp: 0.0 ± 0.0
0.664HisTyr: 0.664 ± 0.396
0.0HisXaa: 0.0 ± 0.0
Ile
1.827IleAla: 1.827 ± 0.6
0.996IleCys: 0.996 ± 0.526
2.823IleAsp: 2.823 ± 1.272
2.823IleGlu: 2.823 ± 0.613
1.661IlePhe: 1.661 ± 0.531
1.993IleGly: 1.993 ± 0.626
1.162IleHis: 1.162 ± 0.394
3.155IleIle: 3.155 ± 2.298
1.162IleLys: 1.162 ± 0.771
2.989IleLeu: 2.989 ± 0.478
0.83IleMet: 0.83 ± 0.513
2.491IleAsn: 2.491 ± 0.618
2.657IlePro: 2.657 ± 0.669
1.162IleGln: 1.162 ± 0.76
2.823IleArg: 2.823 ± 1.198
4.982IleSer: 4.982 ± 1.255
2.491IleThr: 2.491 ± 0.647
4.151IleVal: 4.151 ± 0.922
0.498IleTrp: 0.498 ± 0.315
1.162IleTyr: 1.162 ± 0.614
0.0IleXaa: 0.0 ± 0.0
Lys
3.155LysAla: 3.155 ± 0.834
0.83LysCys: 0.83 ± 0.445
2.491LysAsp: 2.491 ± 0.563
1.661LysGlu: 1.661 ± 0.825
2.989LysPhe: 2.989 ± 2.034
1.993LysGly: 1.993 ± 0.622
1.328LysHis: 1.328 ± 0.386
1.328LysIle: 1.328 ± 0.4
1.827LysLys: 1.827 ± 0.351
6.642LysLeu: 6.642 ± 2.257
0.498LysMet: 0.498 ± 0.366
1.328LysAsn: 1.328 ± 0.284
1.495LysPro: 1.495 ± 0.596
0.664LysGln: 0.664 ± 0.26
3.985LysArg: 3.985 ± 0.798
4.65LysSer: 4.65 ± 0.935
3.321LysThr: 3.321 ± 1.244
6.31LysVal: 6.31 ± 1.118
0.166LysTrp: 0.166 ± 0.245
2.491LysTyr: 2.491 ± 0.989
0.0LysXaa: 0.0 ± 0.0
Leu
6.144LeuAla: 6.144 ± 1.799
1.993LeuCys: 1.993 ± 0.788
5.48LeuAsp: 5.48 ± 0.682
3.819LeuGlu: 3.819 ± 0.694
5.48LeuPhe: 5.48 ± 1.242
6.31LeuGly: 6.31 ± 1.402
1.993LeuHis: 1.993 ± 0.463
3.985LeuIle: 3.985 ± 0.695
5.48LeuLys: 5.48 ± 0.852
10.13LeuLeu: 10.13 ± 1.924
2.159LeuMet: 2.159 ± 0.643
3.155LeuAsn: 3.155 ± 0.551
4.151LeuPro: 4.151 ± 1.168
1.495LeuGln: 1.495 ± 0.538
10.13LeuArg: 10.13 ± 1.766
9.631LeuSer: 9.631 ± 1.05
5.48LeuThr: 5.48 ± 1.032
6.974LeuVal: 6.974 ± 0.993
0.498LeuTrp: 0.498 ± 0.379
3.487LeuTyr: 3.487 ± 0.871
0.0LeuXaa: 0.0 ± 0.0
Met
1.328MetAla: 1.328 ± 1.023
0.332MetCys: 0.332 ± 0.202
1.495MetAsp: 1.495 ± 0.863
0.83MetGlu: 0.83 ± 0.442
0.996MetPhe: 0.996 ± 0.535
1.661MetGly: 1.661 ± 0.751
0.332MetHis: 0.332 ± 0.258
0.332MetIle: 0.332 ± 0.315
0.664MetLys: 0.664 ± 0.472
1.162MetLeu: 1.162 ± 0.714
0.166MetMet: 0.166 ± 0.1
0.996MetAsn: 0.996 ± 0.769
0.996MetPro: 0.996 ± 0.426
0.0MetGln: 0.0 ± 0.0
1.661MetArg: 1.661 ± 0.839
2.823MetSer: 2.823 ± 1.145
1.162MetThr: 1.162 ± 0.471
2.159MetVal: 2.159 ± 0.552
0.0MetTrp: 0.0 ± 0.0
0.498MetTyr: 0.498 ± 0.269
0.0MetXaa: 0.0 ± 0.0
Asn
2.325AsnAla: 2.325 ± 0.739
0.664AsnCys: 0.664 ± 0.39
2.823AsnAsp: 2.823 ± 0.797
2.989AsnGlu: 2.989 ± 0.667
2.325AsnPhe: 2.325 ± 0.771
1.661AsnGly: 1.661 ± 0.566
0.996AsnHis: 0.996 ± 0.459
1.495AsnIle: 1.495 ± 0.721
2.491AsnLys: 2.491 ± 0.669
3.985AsnLeu: 3.985 ± 0.978
0.332AsnMet: 0.332 ± 0.357
1.162AsnAsn: 1.162 ± 0.672
1.162AsnPro: 1.162 ± 0.559
0.996AsnGln: 0.996 ± 0.367
1.661AsnArg: 1.661 ± 0.571
4.318AsnSer: 4.318 ± 0.601
2.823AsnThr: 2.823 ± 0.859
3.155AsnVal: 3.155 ± 1.503
0.166AsnTrp: 0.166 ± 0.216
0.996AsnTyr: 0.996 ± 0.429
0.0AsnXaa: 0.0 ± 0.0
Pro
1.993ProAla: 1.993 ± 0.57
0.996ProCys: 0.996 ± 0.462
2.159ProAsp: 2.159 ± 0.908
0.996ProGlu: 0.996 ± 0.522
2.657ProPhe: 2.657 ± 0.518
1.993ProGly: 1.993 ± 0.822
0.664ProHis: 0.664 ± 0.374
2.491ProIle: 2.491 ± 0.696
1.162ProLys: 1.162 ± 0.335
3.985ProLeu: 3.985 ± 0.718
0.83ProMet: 0.83 ± 0.395
1.328ProAsn: 1.328 ± 0.659
1.827ProPro: 1.827 ± 0.729
0.83ProGln: 0.83 ± 0.479
2.325ProArg: 2.325 ± 1.038
4.484ProSer: 4.484 ± 0.884
1.661ProThr: 1.661 ± 0.689
4.318ProVal: 4.318 ± 0.98
0.166ProTrp: 0.166 ± 0.1
1.661ProTyr: 1.661 ± 0.667
0.0ProXaa: 0.0 ± 0.0
Gln
1.162GlnAla: 1.162 ± 0.411
0.166GlnCys: 0.166 ± 0.1
1.162GlnAsp: 1.162 ± 0.597
0.332GlnGlu: 0.332 ± 0.218
0.664GlnPhe: 0.664 ± 0.277
1.328GlnGly: 1.328 ± 0.825
0.332GlnHis: 0.332 ± 0.202
0.996GlnIle: 0.996 ± 0.506
1.827GlnLys: 1.827 ± 0.52
1.661GlnLeu: 1.661 ± 0.496
0.166GlnMet: 0.166 ± 0.1
1.162GlnAsn: 1.162 ± 0.603
0.498GlnPro: 0.498 ± 0.228
0.332GlnGln: 0.332 ± 0.198
0.664GlnArg: 0.664 ± 0.25
1.495GlnSer: 1.495 ± 0.642
1.993GlnThr: 1.993 ± 0.578
1.162GlnVal: 1.162 ± 0.391
0.0GlnTrp: 0.0 ± 0.0
0.498GlnTyr: 0.498 ± 0.3
0.0GlnXaa: 0.0 ± 0.0
Arg
6.31ArgAla: 6.31 ± 1.14
3.155ArgCys: 3.155 ± 0.718
3.487ArgAsp: 3.487 ± 0.8
2.657ArgGlu: 2.657 ± 0.777
3.985ArgPhe: 3.985 ± 0.798
3.819ArgGly: 3.819 ± 1.054
1.661ArgHis: 1.661 ± 0.561
3.653ArgIle: 3.653 ± 1.091
4.65ArgLys: 4.65 ± 0.859
8.469ArgLeu: 8.469 ± 1.457
1.162ArgMet: 1.162 ± 0.453
3.321ArgAsn: 3.321 ± 0.827
1.495ArgPro: 1.495 ± 0.594
1.661ArgGln: 1.661 ± 0.773
6.808ArgArg: 6.808 ± 1.584
5.978ArgSer: 5.978 ± 0.923
3.321ArgThr: 3.321 ± 0.634
5.978ArgVal: 5.978 ± 1.164
0.664ArgTrp: 0.664 ± 0.265
1.661ArgTyr: 1.661 ± 0.635
0.0ArgXaa: 0.0 ± 0.0
Ser
6.642SerAla: 6.642 ± 1.647
2.159SerCys: 2.159 ± 0.48
5.812SerAsp: 5.812 ± 1.18
6.974SerGlu: 6.974 ± 1.091
5.812SerPhe: 5.812 ± 1.433
6.808SerGly: 6.808 ± 0.68
1.993SerHis: 1.993 ± 0.494
4.65SerIle: 4.65 ± 1.352
4.151SerLys: 4.151 ± 0.711
10.13SerLeu: 10.13 ± 1.215
1.827SerMet: 1.827 ± 0.577
3.653SerAsn: 3.653 ± 0.967
3.155SerPro: 3.155 ± 0.89
1.993SerGln: 1.993 ± 0.468
7.639SerArg: 7.639 ± 1.688
11.956SerSer: 11.956 ± 2.544
3.321SerThr: 3.321 ± 1.131
9.797SerVal: 9.797 ± 1.373
0.83SerTrp: 0.83 ± 0.413
3.985SerTyr: 3.985 ± 0.679
0.0SerXaa: 0.0 ± 0.0
Thr
3.819ThrAla: 3.819 ± 1.059
0.664ThrCys: 0.664 ± 0.25
2.989ThrAsp: 2.989 ± 0.518
2.325ThrGlu: 2.325 ± 1.346
4.151ThrPhe: 4.151 ± 0.778
2.325ThrGly: 2.325 ± 0.787
1.495ThrHis: 1.495 ± 0.642
2.823ThrIle: 2.823 ± 1.063
2.491ThrLys: 2.491 ± 1.07
4.982ThrLeu: 4.982 ± 1.492
1.328ThrMet: 1.328 ± 0.887
2.491ThrAsn: 2.491 ± 1.099
2.325ThrPro: 2.325 ± 0.522
1.328ThrGln: 1.328 ± 0.473
3.487ThrArg: 3.487 ± 0.626
5.314ThrSer: 5.314 ± 0.998
2.657ThrThr: 2.657 ± 1.345
4.816ThrVal: 4.816 ± 1.116
0.332ThrTrp: 0.332 ± 0.218
2.159ThrTyr: 2.159 ± 0.529
0.0ThrXaa: 0.0 ± 0.0
Val
4.982ValAla: 4.982 ± 1.227
2.325ValCys: 2.325 ± 0.876
6.31ValAsp: 6.31 ± 1.126
4.484ValGlu: 4.484 ± 1.038
3.819ValPhe: 3.819 ± 0.741
4.65ValGly: 4.65 ± 0.662
1.328ValHis: 1.328 ± 0.413
3.321ValIle: 3.321 ± 1.059
5.148ValLys: 5.148 ± 1.119
7.307ValLeu: 7.307 ± 0.6
2.657ValMet: 2.657 ± 1.579
3.985ValAsn: 3.985 ± 0.726
6.144ValPro: 6.144 ± 1.436
1.661ValGln: 1.661 ± 0.239
6.808ValArg: 6.808 ± 2.021
11.126ValSer: 11.126 ± 1.713
4.484ValThr: 4.484 ± 0.459
10.628ValVal: 10.628 ± 1.288
0.83ValTrp: 0.83 ± 0.41
2.989ValTyr: 2.989 ± 0.906
0.0ValXaa: 0.0 ± 0.0
Trp
0.166TrpAla: 0.166 ± 0.219
0.332TrpCys: 0.332 ± 0.202
0.83TrpAsp: 0.83 ± 0.374
0.332TrpGlu: 0.332 ± 0.2
0.332TrpPhe: 0.332 ± 0.242
0.498TrpGly: 0.498 ± 0.232
0.0TrpHis: 0.0 ± 0.0
0.332TrpIle: 0.332 ± 0.218
0.166TrpLys: 0.166 ± 0.219
0.498TrpLeu: 0.498 ± 0.395
0.332TrpMet: 0.332 ± 0.218
0.166TrpAsn: 0.166 ± 0.1
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.332TrpArg: 0.332 ± 0.2
0.498TrpSer: 0.498 ± 0.302
0.332TrpThr: 0.332 ± 0.2
0.664TrpVal: 0.664 ± 0.291
0.332TrpTrp: 0.332 ± 0.242
0.498TrpTyr: 0.498 ± 0.395
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.993TyrAla: 1.993 ± 0.633
0.996TyrCys: 0.996 ± 0.462
2.159TyrAsp: 2.159 ± 0.497
2.159TyrGlu: 2.159 ± 0.833
1.993TyrPhe: 1.993 ± 0.873
2.989TyrGly: 2.989 ± 0.471
0.664TyrHis: 0.664 ± 0.284
1.495TyrIle: 1.495 ± 0.535
2.159TyrLys: 2.159 ± 0.723
4.318TyrLeu: 4.318 ± 1.112
0.498TyrMet: 0.498 ± 0.325
1.495TyrAsn: 1.495 ± 0.653
1.495TyrPro: 1.495 ± 0.397
0.996TyrGln: 0.996 ± 0.436
1.661TyrArg: 1.661 ± 0.485
3.985TyrSer: 3.985 ± 0.752
1.827TyrThr: 1.827 ± 0.564
2.823TyrVal: 2.823 ± 0.776
0.166TyrTrp: 0.166 ± 0.1
1.661TyrTyr: 1.661 ± 0.411
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (6023 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski