Amino acid dipepetide frequency for Fusobacterium mortiferum ATCC 9817

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.392AlaAla: 3.392 ± 0.09	0.642AlaCys: 0.642 ± 0.033	2.49AlaAsp: 2.49 ± 0.065	3.662AlaGlu: 3.662 ± 0.077	2.523AlaPhe: 2.523 ± 0.063	4.301AlaGly: 4.301 ± 0.096	0.867AlaHis: 0.867 ± 0.03	5.438AlaIle: 5.438 ± 0.092	4.807AlaLys: 4.807 ± 0.096	5.462AlaLeu: 5.462 ± 0.098	1.717AlaMet: 1.717 ± 0.047	2.386AlaAsn: 2.386 ± 0.049	1.507AlaPro: 1.507 ± 0.042	1.617AlaGln: 1.617 ± 0.049	1.891AlaArg: 1.891 ± 0.046	2.785AlaSer: 2.785 ± 0.061	2.904AlaThr: 2.904 ± 0.064	3.716AlaVal: 3.716 ± 0.089	0.395AlaTrp: 0.395 ± 0.021	2.056AlaTyr: 2.056 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	0.483CysAla: 0.483 ± 0.028	0.125CysCys: 0.125 ± 0.013	0.502CysAsp: 0.502 ± 0.026	0.698CysGlu: 0.698 ± 0.036	0.372CysPhe: 0.372 ± 0.02	1.077CysGly: 1.077 ± 0.038	0.175CysHis: 0.175 ± 0.016	0.792CysIle: 0.792 ± 0.033	0.737CysLys: 0.737 ± 0.034	0.716CysLeu: 0.716 ± 0.032	0.209CysMet: 0.209 ± 0.016	0.474CysAsn: 0.474 ± 0.026	0.43CysPro: 0.43 ± 0.027	0.211CysGln: 0.211 ± 0.016	0.331CysArg: 0.331 ± 0.022	0.603CysSer: 0.603 ± 0.029	0.506CysThr: 0.506 ± 0.026	0.565CysVal: 0.565 ± 0.027	0.058CysTrp: 0.058 ± 0.008	0.343CysTyr: 0.343 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	2.126AspAla: 2.126 ± 0.061	0.437AspCys: 0.437 ± 0.023	2.25AspAsp: 2.25 ± 0.066	4.68AspGlu: 4.68 ± 0.083	2.809AspPhe: 2.809 ± 0.071	3.43AspGly: 3.43 ± 0.077	0.43AspHis: 0.43 ± 0.025	6.157AspIle: 6.157 ± 0.09	5.132AspLys: 5.132 ± 0.085	4.323AspLeu: 4.323 ± 0.085	1.56AspMet: 1.56 ± 0.04	2.785AspAsn: 2.785 ± 0.055	1.091AspPro: 1.091 ± 0.041	0.507AspGln: 0.507 ± 0.026	2.197AspArg: 2.197 ± 0.061	2.892AspSer: 2.892 ± 0.065	2.468AspThr: 2.468 ± 0.055	2.997AspVal: 2.997 ± 0.067	0.435AspTrp: 0.435 ± 0.022	2.565AspTyr: 2.565 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	4.205GluAla: 4.205 ± 0.081	0.591GluCys: 0.591 ± 0.029	4.084GluAsp: 4.084 ± 0.079	8.39GluGlu: 8.39 ± 0.161	3.5GluPhe: 3.5 ± 0.079	4.364GluGly: 4.364 ± 0.077	0.914GluHis: 0.914 ± 0.033	8.773GluIle: 8.773 ± 0.12	10.472GluLys: 10.472 ± 0.161	7.805GluLeu: 7.805 ± 0.119	2.147GluMet: 2.147 ± 0.051	6.194GluAsn: 6.194 ± 0.103	1.261GluPro: 1.261 ± 0.038	1.672GluGln: 1.672 ± 0.054	3.419GluArg: 3.419 ± 0.08	3.311GluSer: 3.311 ± 0.069	3.151GluThr: 3.151 ± 0.06	5.245GluVal: 5.245 ± 0.084	0.565GluTrp: 0.565 ± 0.028	3.799GluTyr: 3.799 ± 0.076	0.0GluXaa: 0.0 ± 0.0
Phe	2.303PheAla: 2.303 ± 0.057	0.422PheCys: 0.422 ± 0.024	2.58PheAsp: 2.58 ± 0.063	3.265PheGlu: 3.265 ± 0.075	2.562PhePhe: 2.562 ± 0.066	3.326PheGly: 3.326 ± 0.064	0.529PheHis: 0.529 ± 0.025	4.838PheIle: 4.838 ± 0.103	3.865PheLys: 3.865 ± 0.073	4.92PheLeu: 4.92 ± 0.093	1.238PheMet: 1.238 ± 0.045	2.536PheAsn: 2.536 ± 0.056	1.37PhePro: 1.37 ± 0.048	1.207PheGln: 1.207 ± 0.04	1.447PheArg: 1.447 ± 0.04	3.662PheSer: 3.662 ± 0.069	2.398PheThr: 2.398 ± 0.059	2.573PheVal: 2.573 ± 0.069	0.347PheTrp: 0.347 ± 0.021	2.112PheTyr: 2.112 ± 0.056	0.0PheXaa: 0.0 ± 0.0
Gly	4.522GlyAla: 4.522 ± 0.094	0.749GlyCys: 0.749 ± 0.032	3.338GlyAsp: 3.338 ± 0.071	5.2GlyGlu: 5.2 ± 0.096	3.001GlyPhe: 3.001 ± 0.076	4.601GlyGly: 4.601 ± 0.098	1.037GlyHis: 1.037 ± 0.036	7.341GlyIle: 7.341 ± 0.127	6.518GlyLys: 6.518 ± 0.114	5.542GlyLeu: 5.542 ± 0.105	1.991GlyMet: 1.991 ± 0.048	3.494GlyAsn: 3.494 ± 0.082	1.084GlyPro: 1.084 ± 0.04	1.358GlyGln: 1.358 ± 0.045	2.339GlyArg: 2.339 ± 0.061	3.323GlySer: 3.323 ± 0.074	3.558GlyThr: 3.558 ± 0.076	5.617GlyVal: 5.617 ± 0.103	0.488GlyTrp: 0.488 ± 0.028	3.195GlyTyr: 3.195 ± 0.071	0.0GlyXaa: 0.0 ± 0.0
His	0.579HisAla: 0.579 ± 0.028	0.173HisCys: 0.173 ± 0.015	0.507HisAsp: 0.507 ± 0.028	0.677HisGlu: 0.677 ± 0.032	0.609HisPhe: 0.609 ± 0.03	0.931HisGly: 0.931 ± 0.039	0.298HisHis: 0.298 ± 0.019	1.247HisIle: 1.247 ± 0.045	0.915HisLys: 0.915 ± 0.039	1.165HisLeu: 1.165 ± 0.041	0.34HisMet: 0.34 ± 0.021	0.655HisAsn: 0.655 ± 0.032	0.606HisPro: 0.606 ± 0.027	0.347HisGln: 0.347 ± 0.023	0.512HisArg: 0.512 ± 0.025	0.844HisSer: 0.844 ± 0.032	0.684HisThr: 0.684 ± 0.032	0.607HisVal: 0.607 ± 0.031	0.098HisTrp: 0.098 ± 0.01	0.544HisTyr: 0.544 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.82IleAla: 5.82 ± 0.095	0.968IleCys: 0.968 ± 0.037	5.506IleAsp: 5.506 ± 0.086	8.063IleGlu: 8.063 ± 0.127	5.09IlePhe: 5.09 ± 0.109	6.514IleGly: 6.514 ± 0.113	1.03IleHis: 1.03 ± 0.039	8.682IleIle: 8.682 ± 0.13	8.477IleLys: 8.477 ± 0.119	9.869IleLeu: 9.869 ± 0.168	2.201IleMet: 2.201 ± 0.055	5.158IleAsn: 5.158 ± 0.091	3.459IlePro: 3.459 ± 0.07	2.017IleGln: 2.017 ± 0.046	3.02IleArg: 3.02 ± 0.062	6.274IleSer: 6.274 ± 0.088	4.929IleThr: 4.929 ± 0.082	6.162IleVal: 6.162 ± 0.091	0.588IleTrp: 0.588 ± 0.03	3.765IleTyr: 3.765 ± 0.075	0.0IleXaa: 0.0 ± 0.0
Lys	4.699LysAla: 4.699 ± 0.093	0.651LysCys: 0.651 ± 0.032	5.502LysAsp: 5.502 ± 0.107	10.019LysGlu: 10.019 ± 0.133	3.848LysPhe: 3.848 ± 0.071	5.203LysGly: 5.203 ± 0.09	0.9LysHis: 0.9 ± 0.034	9.631LysIle: 9.631 ± 0.134	9.774LysLys: 9.774 ± 0.124	8.137LysLeu: 8.137 ± 0.12	2.594LysMet: 2.594 ± 0.058	7.127LysAsn: 7.127 ± 0.117	1.845LysPro: 1.845 ± 0.051	1.737LysGln: 1.737 ± 0.051	3.453LysArg: 3.453 ± 0.077	4.372LysSer: 4.372 ± 0.079	3.962LysThr: 3.962 ± 0.069	6.078LysVal: 6.078 ± 0.093	0.55LysTrp: 0.55 ± 0.023	4.771LysTyr: 4.771 ± 0.08	0.0LysXaa: 0.0 ± 0.0
Leu	5.512LeuAla: 5.512 ± 0.111	0.813LeuCys: 0.813 ± 0.033	5.336LeuAsp: 5.336 ± 0.082	8.401LeuGlu: 8.401 ± 0.125	4.066LeuPhe: 4.066 ± 0.085	7.201LeuGly: 7.201 ± 0.117	1.028LeuHis: 1.028 ± 0.036	7.561LeuIle: 7.561 ± 0.114	9.752LeuLys: 9.752 ± 0.131	8.124LeuLeu: 8.124 ± 0.135	2.19LeuMet: 2.19 ± 0.054	5.286LeuAsn: 5.286 ± 0.09	2.954LeuPro: 2.954 ± 0.058	2.19LeuGln: 2.19 ± 0.054	3.118LeuArg: 3.118 ± 0.069	5.908LeuSer: 5.908 ± 0.086	4.721LeuThr: 4.721 ± 0.081	5.502LeuVal: 5.502 ± 0.099	0.541LeuTrp: 0.541 ± 0.028	3.296LeuTyr: 3.296 ± 0.067	0.0LeuXaa: 0.0 ± 0.0
Met	1.742MetAla: 1.742 ± 0.048	0.212MetCys: 0.212 ± 0.019	1.172MetAsp: 1.172 ± 0.041	2.243MetGlu: 2.243 ± 0.061	0.975MetPhe: 0.975 ± 0.041	2.018MetGly: 2.018 ± 0.048	0.25MetHis: 0.25 ± 0.017	2.185MetIle: 2.185 ± 0.051	2.901MetLys: 2.901 ± 0.067	2.339MetLeu: 2.339 ± 0.05	0.652MetMet: 0.652 ± 0.03	1.441MetAsn: 1.441 ± 0.042	0.759MetPro: 0.759 ± 0.033	0.485MetGln: 0.485 ± 0.025	1.032MetArg: 1.032 ± 0.04	1.465MetSer: 1.465 ± 0.051	1.266MetThr: 1.266 ± 0.038	1.599MetVal: 1.599 ± 0.048	0.16MetTrp: 0.16 ± 0.015	0.824MetTyr: 0.824 ± 0.034	0.0MetXaa: 0.0 ± 0.0
Asn	2.066AsnAla: 2.066 ± 0.062	0.598AsnCys: 0.598 ± 0.029	2.328AsnAsp: 2.328 ± 0.059	3.666AsnGlu: 3.666 ± 0.073	3.076AsnPhe: 3.076 ± 0.073	3.835AsnGly: 3.835 ± 0.082	0.683AsnHis: 0.683 ± 0.031	6.758AsnIle: 6.758 ± 0.107	5.101AsnLys: 5.101 ± 0.097	5.941AsnLeu: 5.941 ± 0.095	1.54AsnMet: 1.54 ± 0.047	3.563AsnAsn: 3.563 ± 0.091	2.309AsnPro: 2.309 ± 0.057	1.333AsnGln: 1.333 ± 0.05	2.318AsnArg: 2.318 ± 0.061	3.829AsnSer: 3.829 ± 0.079	2.467AsnThr: 2.467 ± 0.056	2.761AsnVal: 2.761 ± 0.071	0.422AsnTrp: 0.422 ± 0.023	2.818AsnTyr: 2.818 ± 0.076	0.0AsnXaa: 0.0 ± 0.0
Pro	1.663ProAla: 1.663 ± 0.05	0.295ProCys: 0.295 ± 0.02	1.303ProAsp: 1.303 ± 0.044	2.523ProGlu: 2.523 ± 0.059	1.48ProPhe: 1.48 ± 0.047	1.552ProGly: 1.552 ± 0.053	0.507ProHis: 0.507 ± 0.027	2.58ProIle: 2.58 ± 0.066	2.294ProLys: 2.294 ± 0.057	2.614ProLeu: 2.614 ± 0.056	0.756ProMet: 0.756 ± 0.033	1.614ProAsn: 1.614 ± 0.05	0.543ProPro: 0.543 ± 0.028	0.799ProGln: 0.799 ± 0.027	0.831ProArg: 0.831 ± 0.029	1.453ProSer: 1.453 ± 0.048	1.507ProThr: 1.507 ± 0.048	2.066ProVal: 2.066 ± 0.056	0.216ProTrp: 0.216 ± 0.017	1.19ProTyr: 1.19 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	1.378GlnAla: 1.378 ± 0.05	0.208GlnCys: 0.208 ± 0.019	1.071GlnAsp: 1.071 ± 0.035	2.137GlnGlu: 2.137 ± 0.061	0.813GlnPhe: 0.813 ± 0.034	1.614GlnGly: 1.614 ± 0.052	0.294GlnHis: 0.294 ± 0.018	2.004GlnIle: 2.004 ± 0.054	2.044GlnLys: 2.044 ± 0.055	2.103GlnLeu: 2.103 ± 0.053	0.577GlnMet: 0.577 ± 0.03	1.42GlnAsn: 1.42 ± 0.053	0.489GlnPro: 0.489 ± 0.024	0.503GlnGln: 0.503 ± 0.031	0.901GlnArg: 0.901 ± 0.036	1.063GlnSer: 1.063 ± 0.039	0.977GlnThr: 0.977 ± 0.035	1.387GlnVal: 1.387 ± 0.043	0.195GlnTrp: 0.195 ± 0.014	0.905GlnTyr: 0.905 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.111ArgAla: 2.111 ± 0.054	0.32ArgCys: 0.32 ± 0.025	2.104ArgAsp: 2.104 ± 0.05	4.0ArgGlu: 4.0 ± 0.083	1.548ArgPhe: 1.548 ± 0.042	2.341ArgGly: 2.341 ± 0.057	0.386ArgHis: 0.386 ± 0.022	3.082ArgIle: 3.082 ± 0.059	3.559ArgLys: 3.559 ± 0.077	3.003ArgLeu: 3.003 ± 0.059	0.973ArgMet: 0.973 ± 0.033	1.84ArgAsn: 1.84 ± 0.051	0.815ArgPro: 0.815 ± 0.032	0.746ArgGln: 0.746 ± 0.03	1.45ArgArg: 1.45 ± 0.047	1.27ArgSer: 1.27 ± 0.044	1.505ArgThr: 1.505 ± 0.043	2.872ArgVal: 2.872 ± 0.061	0.252ArgTrp: 0.252 ± 0.019	1.672ArgTyr: 1.672 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	2.93SerAla: 2.93 ± 0.056	0.591SerCys: 0.591 ± 0.027	2.592SerAsp: 2.592 ± 0.058	3.775SerGlu: 3.775 ± 0.072	3.284SerPhe: 3.284 ± 0.078	4.164SerGly: 4.164 ± 0.079	0.799SerHis: 0.799 ± 0.04	5.385SerIle: 5.385 ± 0.085	5.085SerLys: 5.085 ± 0.084	5.79SerLeu: 5.79 ± 0.098	1.337SerMet: 1.337 ± 0.038	3.006SerAsn: 3.006 ± 0.076	1.584SerPro: 1.584 ± 0.051	1.542SerGln: 1.542 ± 0.047	1.966SerArg: 1.966 ± 0.052	3.69SerSer: 3.69 ± 0.097	2.854SerThr: 2.854 ± 0.062	3.296SerVal: 3.296 ± 0.067	0.457SerTrp: 0.457 ± 0.026	2.398SerTyr: 2.398 ± 0.059	0.0SerXaa: 0.0 ± 0.0
Thr	2.861ThrAla: 2.861 ± 0.07	0.452ThrCys: 0.452 ± 0.025	2.336ThrAsp: 2.336 ± 0.053	3.161ThrGlu: 3.161 ± 0.065	2.286ThrPhe: 2.286 ± 0.056	3.765ThrGly: 3.765 ± 0.081	0.767ThrHis: 0.767 ± 0.029	4.467ThrIle: 4.467 ± 0.084	3.754ThrLys: 3.754 ± 0.063	5.1ThrLeu: 5.1 ± 0.084	1.109ThrMet: 1.109 ± 0.041	2.347ThrAsn: 2.347 ± 0.058	2.108ThrPro: 2.108 ± 0.052	1.21ThrGln: 1.21 ± 0.037	1.581ThrArg: 1.581 ± 0.043	2.853ThrSer: 2.853 ± 0.066	2.804ThrThr: 2.804 ± 0.067	3.046ThrVal: 3.046 ± 0.064	0.327ThrTrp: 0.327 ± 0.021	1.93ThrTyr: 1.93 ± 0.055	0.0ThrXaa: 0.0 ± 0.0
Val	4.048ValAla: 4.048 ± 0.081	0.646ValCys: 0.646 ± 0.028	3.552ValAsp: 3.552 ± 0.073	5.59ValGlu: 5.59 ± 0.094	2.85ValPhe: 2.85 ± 0.061	4.554ValGly: 4.554 ± 0.09	0.751ValHis: 0.751 ± 0.027	6.024ValIle: 6.024 ± 0.107	5.565ValLys: 5.565 ± 0.091	5.653ValLeu: 5.653 ± 0.104	1.534ValMet: 1.534 ± 0.043	3.002ValAsn: 3.002 ± 0.058	1.982ValPro: 1.982 ± 0.051	1.279ValGln: 1.279 ± 0.043	2.157ValArg: 2.157 ± 0.051	3.545ValSer: 3.545 ± 0.078	3.209ValThr: 3.209 ± 0.06	4.785ValVal: 4.785 ± 0.098	0.408ValTrp: 0.408 ± 0.023	2.273ValTyr: 2.273 ± 0.06	0.0ValXaa: 0.0 ± 0.0
Trp	0.356TrpAla: 0.356 ± 0.023	0.073TrpCys: 0.073 ± 0.009	0.399TrpAsp: 0.399 ± 0.024	0.625TrpGlu: 0.625 ± 0.03	0.309TrpPhe: 0.309 ± 0.02	0.533TrpGly: 0.533 ± 0.027	0.105TrpHis: 0.105 ± 0.013	0.603TrpIle: 0.603 ± 0.027	0.615TrpLys: 0.615 ± 0.029	0.683TrpLeu: 0.683 ± 0.031	0.145TrpMet: 0.145 ± 0.013	0.433TrpAsn: 0.433 ± 0.027	0.13TrpPro: 0.13 ± 0.015	0.185TrpGln: 0.185 ± 0.015	0.258TrpArg: 0.258 ± 0.019	0.366TrpSer: 0.366 ± 0.025	0.306TrpThr: 0.306 ± 0.021	0.383TrpVal: 0.383 ± 0.025	0.095TrpTrp: 0.095 ± 0.012	0.312TrpTyr: 0.312 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.76TyrAla: 1.76 ± 0.049	0.443TyrCys: 0.443 ± 0.025	2.319TyrAsp: 2.319 ± 0.065	3.088TyrGlu: 3.088 ± 0.076	2.497TyrPhe: 2.497 ± 0.062	2.972TyrGly: 2.972 ± 0.066	0.587TyrHis: 0.587 ± 0.027	4.042TyrIle: 4.042 ± 0.082	3.486TyrLys: 3.486 ± 0.079	4.211TyrLeu: 4.211 ± 0.084	0.91TyrMet: 0.91 ± 0.036	2.651TyrAsn: 2.651 ± 0.067	1.46TyrPro: 1.46 ± 0.051	1.139TyrGln: 1.139 ± 0.043	1.628TyrArg: 1.628 ± 0.055	3.019TyrSer: 3.019 ± 0.066	2.085TyrThr: 2.085 ± 0.054	2.153TyrVal: 2.153 ± 0.051	0.317TyrTrp: 0.317 ± 0.019	2.086TyrTyr: 2.086 ± 0.065	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2532 proteins (778824 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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