Amino acid dipepetide frequency for Pompano iridovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.709AlaAla: 8.709 ± 0.615
2.101AlaCys: 2.101 ± 0.28
4.506AlaAsp: 4.506 ± 0.389
3.428AlaGlu: 3.428 ± 0.376
3.179AlaPhe: 3.179 ± 0.359
3.732AlaGly: 3.732 ± 0.359
3.096AlaHis: 3.096 ± 0.331
3.649AlaIle: 3.649 ± 0.307
2.709AlaLys: 2.709 ± 0.28
7.658AlaLeu: 7.658 ± 0.671
3.566AlaMet: 3.566 ± 0.409
3.179AlaAsn: 3.179 ± 0.277
4.7AlaPro: 4.7 ± 0.546
3.76AlaGln: 3.76 ± 0.35
5.833AlaArg: 5.833 ± 0.487
4.479AlaSer: 4.479 ± 0.376
6.276AlaThr: 6.276 ± 0.409
7.409AlaVal: 7.409 ± 0.555
0.995AlaTrp: 0.995 ± 0.207
3.152AlaTyr: 3.152 ± 0.286
0.0AlaXaa: 0.0 ± 0.0
Cys
2.709CysAla: 2.709 ± 0.289
0.802CysCys: 0.802 ± 0.152
2.184CysAsp: 2.184 ± 0.304
1.493CysGlu: 1.493 ± 0.243
0.691CysPhe: 0.691 ± 0.12
1.88CysGly: 1.88 ± 0.256
1.216CysHis: 1.216 ± 0.277
1.189CysIle: 1.189 ± 0.164
1.299CysLys: 1.299 ± 0.252
1.908CysLeu: 1.908 ± 0.314
1.161CysMet: 1.161 ± 0.188
1.189CysAsn: 1.189 ± 0.192
1.742CysPro: 1.742 ± 0.465
1.051CysGln: 1.051 ± 0.169
1.769CysArg: 1.769 ± 0.243
1.825CysSer: 1.825 ± 0.252
1.935CysThr: 1.935 ± 0.284
3.152CysVal: 3.152 ± 0.336
0.249CysTrp: 0.249 ± 0.081
0.995CysTyr: 0.995 ± 0.173
0.0CysXaa: 0.0 ± 0.0
Asp
5.198AspAla: 5.198 ± 0.452
1.631AspCys: 1.631 ± 0.291
4.285AspAsp: 4.285 ± 0.469
2.378AspGlu: 2.378 ± 0.287
1.548AspPhe: 1.548 ± 0.23
4.092AspGly: 4.092 ± 0.385
1.548AspHis: 1.548 ± 0.222
4.064AspIle: 4.064 ± 0.349
2.212AspLys: 2.212 ± 0.265
3.373AspLeu: 3.373 ± 0.31
3.262AspMet: 3.262 ± 0.287
2.654AspAsn: 2.654 ± 0.224
2.682AspPro: 2.682 ± 0.333
1.548AspGln: 1.548 ± 0.224
3.511AspArg: 3.511 ± 0.317
3.566AspSer: 3.566 ± 0.362
4.645AspThr: 4.645 ± 0.36
5.889AspVal: 5.889 ± 0.495
0.553AspTrp: 0.553 ± 0.123
2.239AspTyr: 2.239 ± 0.282
0.0AspXaa: 0.0 ± 0.0
Glu
3.207GluAla: 3.207 ± 0.306
1.521GluCys: 1.521 ± 0.247
2.654GluAsp: 2.654 ± 0.363
2.184GluGlu: 2.184 ± 0.525
0.968GluPhe: 0.968 ± 0.183
2.267GluGly: 2.267 ± 0.29
1.686GluHis: 1.686 ± 0.233
1.493GluIle: 1.493 ± 0.204
0.857GluLys: 0.857 ± 0.17
3.069GluLeu: 3.069 ± 0.295
1.465GluMet: 1.465 ± 0.171
1.161GluAsn: 1.161 ± 0.186
2.212GluPro: 2.212 ± 0.459
2.101GluGln: 2.101 ± 0.258
3.041GluArg: 3.041 ± 0.281
1.797GluSer: 1.797 ± 0.222
2.433GluThr: 2.433 ± 0.229
2.571GluVal: 2.571 ± 0.346
0.719GluTrp: 0.719 ± 0.176
2.322GluTyr: 2.322 ± 0.3
0.0GluXaa: 0.0 ± 0.0
Phe
2.516PheAla: 2.516 ± 0.272
0.719PheCys: 0.719 ± 0.128
2.516PheAsp: 2.516 ± 0.283
1.797PheGlu: 1.797 ± 0.204
1.134PhePhe: 1.134 ± 0.174
1.465PheGly: 1.465 ± 0.19
0.829PheHis: 0.829 ± 0.132
1.382PheIle: 1.382 ± 0.179
1.659PheLys: 1.659 ± 0.217
1.714PheLeu: 1.714 ± 0.226
1.438PheMet: 1.438 ± 0.219
1.41PheAsn: 1.41 ± 0.2
1.134PhePro: 1.134 ± 0.168
0.912PheGln: 0.912 ± 0.158
1.41PheArg: 1.41 ± 0.204
1.769PheSer: 1.769 ± 0.236
2.295PheThr: 2.295 ± 0.26
3.041PheVal: 3.041 ± 0.349
0.332PheTrp: 0.332 ± 0.088
0.746PheTyr: 0.746 ± 0.135
0.0PheXaa: 0.0 ± 0.0
Gly
4.7GlyAla: 4.7 ± 0.35
1.161GlyCys: 1.161 ± 0.204
3.096GlyAsp: 3.096 ± 0.27
1.742GlyGlu: 1.742 ± 0.25
1.742GlyPhe: 1.742 ± 0.218
3.981GlyGly: 3.981 ± 0.325
2.488GlyHis: 2.488 ± 0.25
2.461GlyIle: 2.461 ± 0.281
1.825GlyLys: 1.825 ± 0.21
3.843GlyLeu: 3.843 ± 0.274
2.35GlyMet: 2.35 ± 0.265
2.073GlyAsn: 2.073 ± 0.28
2.931GlyPro: 2.931 ± 0.323
2.433GlyGln: 2.433 ± 0.31
3.235GlyArg: 3.235 ± 0.268
2.709GlySer: 2.709 ± 0.34
4.202GlyThr: 4.202 ± 0.398
5.336GlyVal: 5.336 ± 0.34
0.581GlyTrp: 0.581 ± 0.145
2.654GlyTyr: 2.654 ± 0.289
0.0GlyXaa: 0.0 ± 0.0
His
2.875HisAla: 2.875 ± 0.254
1.078HisCys: 1.078 ± 0.185
1.935HisAsp: 1.935 ± 0.24
1.299HisGlu: 1.299 ± 0.204
0.719HisPhe: 0.719 ± 0.143
2.488HisGly: 2.488 ± 0.257
1.106HisHis: 1.106 ± 0.244
2.488HisIle: 2.488 ± 0.31
1.299HisLys: 1.299 ± 0.177
2.654HisLeu: 2.654 ± 0.228
1.686HisMet: 1.686 ± 0.207
1.991HisAsn: 1.991 ± 0.246
1.106HisPro: 1.106 ± 0.19
0.968HisGln: 0.968 ± 0.163
2.737HisArg: 2.737 ± 0.455
1.935HisSer: 1.935 ± 0.231
3.069HisThr: 3.069 ± 0.362
3.815HisVal: 3.815 ± 0.388
0.359HisTrp: 0.359 ± 0.097
1.161HisTyr: 1.161 ± 0.169
0.0HisXaa: 0.0 ± 0.0
Ile
3.815IleAla: 3.815 ± 0.299
1.382IleCys: 1.382 ± 0.223
3.152IleAsp: 3.152 ± 0.297
2.184IleGlu: 2.184 ± 0.291
1.189IlePhe: 1.189 ± 0.148
2.571IleGly: 2.571 ± 0.28
1.493IleHis: 1.493 ± 0.2
2.571IleIle: 2.571 ± 0.298
2.129IleLys: 2.129 ± 0.276
3.29IleLeu: 3.29 ± 0.325
2.212IleMet: 2.212 ± 0.233
1.963IleAsn: 1.963 ± 0.221
2.295IlePro: 2.295 ± 0.284
1.714IleGln: 1.714 ± 0.239
2.626IleArg: 2.626 ± 0.287
2.654IleSer: 2.654 ± 0.289
2.543IleThr: 2.543 ± 0.267
4.092IleVal: 4.092 ± 0.353
0.442IleTrp: 0.442 ± 0.107
1.521IleTyr: 1.521 ± 0.232
0.0IleXaa: 0.0 ± 0.0
Lys
2.654LysAla: 2.654 ± 0.339
0.94LysCys: 0.94 ± 0.16
1.797LysAsp: 1.797 ± 0.201
1.438LysGlu: 1.438 ± 0.229
0.968LysPhe: 0.968 ± 0.171
1.659LysGly: 1.659 ± 0.249
1.327LysHis: 1.327 ± 0.17
1.355LysIle: 1.355 ± 0.211
1.216LysLys: 1.216 ± 0.296
2.931LysLeu: 2.931 ± 0.26
1.41LysMet: 1.41 ± 0.184
1.299LysAsn: 1.299 ± 0.202
2.212LysPro: 2.212 ± 0.35
1.714LysGln: 1.714 ± 0.246
2.82LysArg: 2.82 ± 0.396
1.465LysSer: 1.465 ± 0.219
2.488LysThr: 2.488 ± 0.265
2.516LysVal: 2.516 ± 0.292
0.47LysTrp: 0.47 ± 0.106
1.493LysTyr: 1.493 ± 0.223
0.0LysXaa: 0.0 ± 0.0
Leu
7.105LeuAla: 7.105 ± 0.544
3.013LeuCys: 3.013 ± 0.268
4.562LeuAsp: 4.562 ± 0.334
3.152LeuGlu: 3.152 ± 0.346
2.82LeuPhe: 2.82 ± 0.287
3.788LeuGly: 3.788 ± 0.359
3.262LeuHis: 3.262 ± 0.283
3.179LeuIle: 3.179 ± 0.345
3.013LeuLys: 3.013 ± 0.276
8.432LeuLeu: 8.432 ± 0.449
3.29LeuMet: 3.29 ± 0.353
2.461LeuAsn: 2.461 ± 0.252
4.285LeuPro: 4.285 ± 0.328
3.76LeuGln: 3.76 ± 0.456
5.529LeuArg: 5.529 ± 0.459
4.866LeuSer: 4.866 ± 0.304
5.253LeuThr: 5.253 ± 0.403
5.529LeuVal: 5.529 ± 0.541
1.134LeuTrp: 1.134 ± 0.168
3.096LeuTyr: 3.096 ± 0.331
0.0LeuXaa: 0.0 ± 0.0
Met
4.423MetAla: 4.423 ± 0.366
1.88MetCys: 1.88 ± 0.239
2.488MetAsp: 2.488 ± 0.221
1.548MetGlu: 1.548 ± 0.233
1.327MetPhe: 1.327 ± 0.196
1.576MetGly: 1.576 ± 0.202
1.161MetHis: 1.161 ± 0.143
1.465MetIle: 1.465 ± 0.183
0.94MetLys: 0.94 ± 0.14
3.926MetLeu: 3.926 ± 0.355
1.355MetMet: 1.355 ± 0.206
0.968MetAsn: 0.968 ± 0.147
2.848MetPro: 2.848 ± 0.263
1.548MetGln: 1.548 ± 0.231
2.682MetArg: 2.682 ± 0.283
3.235MetSer: 3.235 ± 0.341
2.82MetThr: 2.82 ± 0.311
2.461MetVal: 2.461 ± 0.275
0.415MetTrp: 0.415 ± 0.096
2.295MetTyr: 2.295 ± 0.279
0.0MetXaa: 0.0 ± 0.0
Asn
2.931AsnAla: 2.931 ± 0.298
0.664AsnCys: 0.664 ± 0.113
1.548AsnAsp: 1.548 ± 0.215
1.299AsnGlu: 1.299 ± 0.19
0.885AsnPhe: 0.885 ± 0.179
2.654AsnGly: 2.654 ± 0.277
0.885AsnHis: 0.885 ± 0.146
2.626AsnIle: 2.626 ± 0.274
1.742AsnLys: 1.742 ± 0.183
2.737AsnLeu: 2.737 ± 0.276
1.603AsnMet: 1.603 ± 0.219
1.935AsnAsn: 1.935 ± 0.228
2.101AsnPro: 2.101 ± 0.303
0.802AsnGln: 0.802 ± 0.132
2.018AsnArg: 2.018 ± 0.269
2.239AsnSer: 2.239 ± 0.242
3.705AsnThr: 3.705 ± 0.339
3.539AsnVal: 3.539 ± 0.367
0.166AsnTrp: 0.166 ± 0.065
1.106AsnTyr: 1.106 ± 0.183
0.0AsnXaa: 0.0 ± 0.0
Pro
3.788ProAla: 3.788 ± 0.373
1.852ProCys: 1.852 ± 0.316
4.202ProAsp: 4.202 ± 0.656
2.765ProGlu: 2.765 ± 0.607
1.797ProPhe: 1.797 ± 0.233
3.041ProGly: 3.041 ± 0.362
1.963ProHis: 1.963 ± 0.259
2.156ProIle: 2.156 ± 0.283
1.603ProLys: 1.603 ± 0.283
4.755ProLeu: 4.755 ± 0.527
1.686ProMet: 1.686 ± 0.182
1.88ProAsn: 1.88 ± 0.235
4.175ProPro: 4.175 ± 0.682
2.322ProGln: 2.322 ± 0.26
2.516ProArg: 2.516 ± 0.289
2.986ProSer: 2.986 ± 0.304
3.539ProThr: 3.539 ± 0.443
5.391ProVal: 5.391 ± 0.467
0.47ProTrp: 0.47 ± 0.116
2.156ProTyr: 2.156 ± 0.31
0.0ProXaa: 0.0 ± 0.0
Gln
2.986GlnAla: 2.986 ± 0.286
1.742GlnCys: 1.742 ± 0.376
2.129GlnAsp: 2.129 ± 0.388
1.355GlnGlu: 1.355 ± 0.223
1.327GlnPhe: 1.327 ± 0.209
1.714GlnGly: 1.714 ± 0.221
1.991GlnHis: 1.991 ± 0.225
1.023GlnIle: 1.023 ± 0.152
0.995GlnLys: 0.995 ± 0.156
3.898GlnLeu: 3.898 ± 0.37
1.603GlnMet: 1.603 ± 0.196
0.774GlnAsn: 0.774 ± 0.132
2.018GlnPro: 2.018 ± 0.304
2.461GlnGln: 2.461 ± 0.319
2.875GlnArg: 2.875 ± 0.346
2.046GlnSer: 2.046 ± 0.266
2.184GlnThr: 2.184 ± 0.311
2.682GlnVal: 2.682 ± 0.266
0.636GlnTrp: 0.636 ± 0.125
2.046GlnTyr: 2.046 ± 0.198
0.0GlnXaa: 0.0 ± 0.0
Arg
5.225ArgAla: 5.225 ± 0.503
1.88ArgCys: 1.88 ± 0.268
3.788ArgAsp: 3.788 ± 0.353
2.212ArgGlu: 2.212 ± 0.293
1.797ArgPhe: 1.797 ± 0.226
2.792ArgGly: 2.792 ± 0.242
3.152ArgHis: 3.152 ± 0.34
3.013ArgIle: 3.013 ± 0.349
1.659ArgLys: 1.659 ± 0.231
5.032ArgLeu: 5.032 ± 0.382
2.322ArgMet: 2.322 ± 0.273
2.35ArgAsn: 2.35 ± 0.262
3.953ArgPro: 3.953 ± 0.728
2.322ArgGln: 2.322 ± 0.2
5.363ArgArg: 5.363 ± 0.679
3.428ArgSer: 3.428 ± 0.4
3.76ArgThr: 3.76 ± 0.335
5.861ArgVal: 5.861 ± 0.434
0.885ArgTrp: 0.885 ± 0.172
2.322ArgTyr: 2.322 ± 0.267
0.0ArgXaa: 0.0 ± 0.0
Ser
4.7SerAla: 4.7 ± 0.301
1.769SerCys: 1.769 ± 0.265
3.428SerAsp: 3.428 ± 0.377
1.797SerGlu: 1.797 ± 0.196
1.41SerPhe: 1.41 ± 0.208
4.119SerGly: 4.119 ± 0.337
1.852SerHis: 1.852 ± 0.239
2.626SerIle: 2.626 ± 0.239
2.212SerLys: 2.212 ± 0.321
4.783SerLeu: 4.783 ± 0.333
2.488SerMet: 2.488 ± 0.253
2.046SerAsn: 2.046 ± 0.233
3.179SerPro: 3.179 ± 0.486
1.686SerGln: 1.686 ± 0.225
3.318SerArg: 3.318 ± 0.273
3.788SerSer: 3.788 ± 0.407
3.705SerThr: 3.705 ± 0.323
5.225SerVal: 5.225 ± 0.455
0.387SerTrp: 0.387 ± 0.095
1.797SerTyr: 1.797 ± 0.21
0.0SerXaa: 0.0 ± 0.0
Thr
6.386ThrAla: 6.386 ± 0.464
1.963ThrCys: 1.963 ± 0.298
4.009ThrAsp: 4.009 ± 0.362
3.262ThrGlu: 3.262 ± 0.353
2.073ThrPhe: 2.073 ± 0.23
4.451ThrGly: 4.451 ± 0.337
2.709ThrHis: 2.709 ± 0.352
2.765ThrIle: 2.765 ± 0.287
2.239ThrLys: 2.239 ± 0.248
6.635ThrLeu: 6.635 ± 0.453
2.958ThrMet: 2.958 ± 0.257
2.129ThrAsn: 2.129 ± 0.275
4.313ThrPro: 4.313 ± 0.36
2.433ThrGln: 2.433 ± 0.27
3.29ThrArg: 3.29 ± 0.322
3.732ThrSer: 3.732 ± 0.319
5.502ThrThr: 5.502 ± 1.273
6.773ThrVal: 6.773 ± 0.508
0.829ThrTrp: 0.829 ± 0.133
2.378ThrTyr: 2.378 ± 0.309
0.0ThrXaa: 0.0 ± 0.0
Val
7.99ValAla: 7.99 ± 0.514
2.931ValCys: 2.931 ± 0.391
5.115ValAsp: 5.115 ± 0.395
2.295ValGlu: 2.295 ± 0.232
3.069ValPhe: 3.069 ± 0.288
4.423ValGly: 4.423 ± 0.304
3.843ValHis: 3.843 ± 0.43
3.566ValIle: 3.566 ± 0.265
2.626ValLys: 2.626 ± 0.272
7.852ValLeu: 7.852 ± 0.59
3.041ValMet: 3.041 ± 0.251
2.682ValAsn: 2.682 ± 0.35
5.391ValPro: 5.391 ± 0.436
3.124ValGln: 3.124 ± 0.323
5.529ValArg: 5.529 ± 0.41
5.225ValSer: 5.225 ± 0.384
6.359ValThr: 6.359 ± 0.501
6.469ValVal: 6.469 ± 0.524
0.94ValTrp: 0.94 ± 0.149
3.705ValTyr: 3.705 ± 0.436
0.0ValXaa: 0.0 ± 0.0
Trp
0.912TrpAla: 0.912 ± 0.17
0.498TrpCys: 0.498 ± 0.107
0.581TrpAsp: 0.581 ± 0.12
0.47TrpGlu: 0.47 ± 0.116
0.415TrpPhe: 0.415 ± 0.125
0.498TrpGly: 0.498 ± 0.118
0.359TrpHis: 0.359 ± 0.097
0.387TrpIle: 0.387 ± 0.113
0.249TrpLys: 0.249 ± 0.089
1.106TrpLeu: 1.106 ± 0.163
0.415TrpMet: 0.415 ± 0.116
0.498TrpAsn: 0.498 ± 0.118
0.691TrpPro: 0.691 ± 0.134
0.857TrpGln: 0.857 ± 0.139
0.608TrpArg: 0.608 ± 0.119
0.47TrpSer: 0.47 ± 0.125
0.774TrpThr: 0.774 ± 0.16
0.581TrpVal: 0.581 ± 0.111
0.221TrpTrp: 0.221 ± 0.089
0.525TrpTyr: 0.525 ± 0.131
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.29TyrAla: 3.29 ± 0.312
0.912TyrCys: 0.912 ± 0.137
2.903TyrAsp: 2.903 ± 0.305
1.631TyrGlu: 1.631 ± 0.221
1.161TyrPhe: 1.161 ± 0.183
2.35TyrGly: 2.35 ± 0.273
0.802TyrHis: 0.802 ± 0.129
2.378TyrIle: 2.378 ± 0.278
1.686TyrLys: 1.686 ± 0.217
1.935TyrLeu: 1.935 ± 0.194
2.018TyrMet: 2.018 ± 0.256
2.543TyrAsn: 2.543 ± 0.276
1.078TyrPro: 1.078 ± 0.169
0.968TyrGln: 0.968 ± 0.156
2.405TyrArg: 2.405 ± 0.212
2.101TyrSer: 2.101 ± 0.224
3.345TyrThr: 3.345 ± 0.275
3.843TyrVal: 3.843 ± 0.318
0.332TyrTrp: 0.332 ± 0.081
1.465TyrTyr: 1.465 ± 0.182
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 121 proteins (36172 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski