Amino acid dipepetide frequency for Acinetobacter phage AbTZA1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.254AlaAla: 5.254 ± 0.392
0.535AlaCys: 0.535 ± 0.105
3.477AlaAsp: 3.477 ± 0.28
4.451AlaGlu: 4.451 ± 0.314
2.675AlaPhe: 2.675 ± 0.241
4.413AlaGly: 4.413 ± 0.377
1.051AlaHis: 1.051 ± 0.134
5.98AlaIle: 5.98 ± 0.359
5.903AlaLys: 5.903 ± 0.403
6.4AlaLeu: 6.4 ± 0.351
1.662AlaMet: 1.662 ± 0.198
4.241AlaAsn: 4.241 ± 0.267
2.579AlaPro: 2.579 ± 0.287
2.866AlaGln: 2.866 ± 0.243
2.675AlaArg: 2.675 ± 0.221
4.299AlaSer: 4.299 ± 0.326
4.719AlaThr: 4.719 ± 0.409
4.241AlaVal: 4.241 ± 0.313
0.917AlaTrp: 0.917 ± 0.156
2.541AlaTyr: 2.541 ± 0.219
0.0AlaXaa: 0.0 ± 0.0
Cys
0.688CysAla: 0.688 ± 0.115
0.153CysCys: 0.153 ± 0.062
0.726CysAsp: 0.726 ± 0.129
0.611CysGlu: 0.611 ± 0.118
0.401CysPhe: 0.401 ± 0.081
0.669CysGly: 0.669 ± 0.114
0.229CysHis: 0.229 ± 0.07
0.745CysIle: 0.745 ± 0.143
0.783CysLys: 0.783 ± 0.129
0.65CysLeu: 0.65 ± 0.1
0.191CysMet: 0.191 ± 0.055
0.573CysAsn: 0.573 ± 0.113
0.459CysPro: 0.459 ± 0.108
0.401CysGln: 0.401 ± 0.084
0.63CysArg: 0.63 ± 0.112
0.86CysSer: 0.86 ± 0.163
0.63CysThr: 0.63 ± 0.114
0.745CysVal: 0.745 ± 0.12
0.172CysTrp: 0.172 ± 0.054
0.382CysTyr: 0.382 ± 0.082
0.0CysXaa: 0.0 ± 0.0
Asp
4.738AspAla: 4.738 ± 0.317
0.764AspCys: 0.764 ± 0.122
3.859AspAsp: 3.859 ± 0.361
4.585AspGlu: 4.585 ± 0.335
2.942AspPhe: 2.942 ± 0.257
4.203AspGly: 4.203 ± 0.287
1.223AspHis: 1.223 ± 0.153
4.509AspIle: 4.509 ± 0.293
4.662AspLys: 4.662 ± 0.329
5.063AspLeu: 5.063 ± 0.302
1.528AspMet: 1.528 ± 0.181
3.095AspAsn: 3.095 ± 0.215
2.503AspPro: 2.503 ± 0.222
1.567AspGln: 1.567 ± 0.149
2.121AspArg: 2.121 ± 0.22
3.706AspSer: 3.706 ± 0.298
3.171AspThr: 3.171 ± 0.266
3.764AspVal: 3.764 ± 0.278
1.051AspTrp: 1.051 ± 0.133
2.789AspTyr: 2.789 ± 0.244
0.0AspXaa: 0.0 ± 0.0
Glu
4.222GluAla: 4.222 ± 0.33
0.822GluCys: 0.822 ± 0.111
3.63GluAsp: 3.63 ± 0.291
3.936GluGlu: 3.936 ± 0.327
3.936GluPhe: 3.936 ± 0.332
2.942GluGly: 2.942 ± 0.248
1.28GluHis: 1.28 ± 0.211
5.521GluIle: 5.521 ± 0.344
4.356GluLys: 4.356 ± 0.271
7.183GluLeu: 7.183 ± 0.379
1.796GluMet: 1.796 ± 0.202
3.573GluAsn: 3.573 ± 0.257
1.872GluPro: 1.872 ± 0.194
2.732GluGln: 2.732 ± 0.243
3.076GluArg: 3.076 ± 0.22
3.936GluSer: 3.936 ± 0.294
4.279GluThr: 4.279 ± 0.304
4.471GluVal: 4.471 ± 0.288
0.707GluTrp: 0.707 ± 0.112
3.038GluTyr: 3.038 ± 0.227
0.0GluXaa: 0.0 ± 0.0
Phe
2.828PheAla: 2.828 ± 0.205
0.401PheCys: 0.401 ± 0.086
3.821PheAsp: 3.821 ± 0.254
3.515PheGlu: 3.515 ± 0.3
1.452PhePhe: 1.452 ± 0.214
3.171PheGly: 3.171 ± 0.238
0.726PheHis: 0.726 ± 0.103
3.553PheIle: 3.553 ± 0.266
3.783PheLys: 3.783 ± 0.239
2.636PheLeu: 2.636 ± 0.222
1.204PheMet: 1.204 ± 0.161
2.942PheAsn: 2.942 ± 0.242
1.433PhePro: 1.433 ± 0.173
1.089PheGln: 1.089 ± 0.152
1.719PheArg: 1.719 ± 0.152
2.961PheSer: 2.961 ± 0.232
2.579PheThr: 2.579 ± 0.269
2.885PheVal: 2.885 ± 0.215
0.611PheTrp: 0.611 ± 0.108
1.853PheTyr: 1.853 ± 0.236
0.0PheXaa: 0.0 ± 0.0
Gly
4.184GlyAla: 4.184 ± 0.327
0.459GlyCys: 0.459 ± 0.09
3.649GlyAsp: 3.649 ± 0.317
3.84GlyGlu: 3.84 ± 0.267
2.426GlyPhe: 2.426 ± 0.224
3.019GlyGly: 3.019 ± 0.311
0.917GlyHis: 0.917 ± 0.161
4.566GlyIle: 4.566 ± 0.246
4.356GlyLys: 4.356 ± 0.302
4.241GlyLeu: 4.241 ± 0.287
1.681GlyMet: 1.681 ± 0.192
3.171GlyAsn: 3.171 ± 0.302
1.719GlyPro: 1.719 ± 0.201
1.834GlyGln: 1.834 ± 0.2
2.369GlyArg: 2.369 ± 0.222
4.012GlySer: 4.012 ± 0.329
4.108GlyThr: 4.108 ± 0.469
3.764GlyVal: 3.764 ± 0.242
0.974GlyTrp: 0.974 ± 0.128
2.675GlyTyr: 2.675 ± 0.237
0.0GlyXaa: 0.0 ± 0.0
His
1.242HisAla: 1.242 ± 0.187
0.267HisCys: 0.267 ± 0.063
1.376HisAsp: 1.376 ± 0.179
0.936HisGlu: 0.936 ± 0.129
1.108HisPhe: 1.108 ± 0.14
1.146HisGly: 1.146 ± 0.149
0.516HisHis: 0.516 ± 0.128
1.567HisIle: 1.567 ± 0.179
1.261HisLys: 1.261 ± 0.159
1.567HisLeu: 1.567 ± 0.2
0.382HisMet: 0.382 ± 0.09
0.86HisAsn: 0.86 ± 0.132
0.917HisPro: 0.917 ± 0.126
0.65HisGln: 0.65 ± 0.108
0.917HisArg: 0.917 ± 0.143
1.242HisSer: 1.242 ± 0.153
1.204HisThr: 1.204 ± 0.141
1.376HisVal: 1.376 ± 0.154
0.229HisTrp: 0.229 ± 0.064
0.516HisTyr: 0.516 ± 0.103
0.0HisXaa: 0.0 ± 0.0
Ile
5.98IleAla: 5.98 ± 0.392
0.917IleCys: 0.917 ± 0.15
5.33IleAsp: 5.33 ± 0.353
6.19IleGlu: 6.19 ± 0.307
2.808IlePhe: 2.808 ± 0.238
4.127IleGly: 4.127 ± 0.28
1.414IleHis: 1.414 ± 0.184
4.795IleIle: 4.795 ± 0.305
5.884IleLys: 5.884 ± 0.356
4.872IleLeu: 4.872 ± 0.334
1.834IleMet: 1.834 ± 0.203
4.299IleAsn: 4.299 ± 0.284
2.636IlePro: 2.636 ± 0.239
2.866IleGln: 2.866 ± 0.268
3.592IleArg: 3.592 ± 0.262
5.311IleSer: 5.311 ± 0.32
4.776IleThr: 4.776 ± 0.343
4.337IleVal: 4.337 ± 0.359
0.764IleTrp: 0.764 ± 0.133
2.331IleTyr: 2.331 ± 0.232
0.0IleXaa: 0.0 ± 0.0
Lys
5.177LysAla: 5.177 ± 0.349
0.802LysCys: 0.802 ± 0.133
4.432LysAsp: 4.432 ± 0.282
4.279LysGlu: 4.279 ± 0.345
4.088LysPhe: 4.088 ± 0.319
3.764LysGly: 3.764 ± 0.265
1.93LysHis: 1.93 ± 0.203
5.464LysIle: 5.464 ± 0.33
3.764LysLys: 3.764 ± 0.318
6.878LysLeu: 6.878 ± 0.371
2.006LysMet: 2.006 ± 0.188
3.783LysAsn: 3.783 ± 0.262
2.082LysPro: 2.082 ± 0.186
2.331LysGln: 2.331 ± 0.237
2.98LysArg: 2.98 ± 0.278
4.337LysSer: 4.337 ± 0.317
4.279LysThr: 4.279 ± 0.303
4.986LysVal: 4.986 ± 0.293
0.879LysTrp: 0.879 ± 0.118
3.267LysTyr: 3.267 ± 0.288
0.0LysXaa: 0.0 ± 0.0
Leu
5.77LeuAla: 5.77 ± 0.355
0.86LeuCys: 0.86 ± 0.134
5.712LeuAsp: 5.712 ± 0.287
5.407LeuGlu: 5.407 ± 0.341
3.439LeuPhe: 3.439 ± 0.337
4.088LeuGly: 4.088 ± 0.283
1.414LeuHis: 1.414 ± 0.142
4.719LeuIle: 4.719 ± 0.28
6.4LeuLys: 6.4 ± 0.384
5.502LeuLeu: 5.502 ± 0.356
2.121LeuMet: 2.121 ± 0.198
5.005LeuAsn: 5.005 ± 0.314
3.42LeuPro: 3.42 ± 0.234
2.503LeuGln: 2.503 ± 0.216
3.343LeuArg: 3.343 ± 0.261
5.063LeuSer: 5.063 ± 0.256
5.139LeuThr: 5.139 ± 0.26
5.407LeuVal: 5.407 ± 0.295
0.841LeuTrp: 0.841 ± 0.122
2.999LeuTyr: 2.999 ± 0.228
0.0LeuXaa: 0.0 ± 0.0
Met
2.006MetAla: 2.006 ± 0.185
0.325MetCys: 0.325 ± 0.08
1.528MetAsp: 1.528 ± 0.187
1.414MetGlu: 1.414 ± 0.18
1.165MetPhe: 1.165 ± 0.174
0.917MetGly: 0.917 ± 0.139
0.554MetHis: 0.554 ± 0.109
1.547MetIle: 1.547 ± 0.165
2.407MetLys: 2.407 ± 0.242
2.044MetLeu: 2.044 ± 0.201
0.554MetMet: 0.554 ± 0.093
1.414MetAsn: 1.414 ± 0.17
0.974MetPro: 0.974 ± 0.127
1.089MetGln: 1.089 ± 0.154
0.955MetArg: 0.955 ± 0.123
2.178MetSer: 2.178 ± 0.173
1.567MetThr: 1.567 ± 0.181
1.433MetVal: 1.433 ± 0.174
0.287MetTrp: 0.287 ± 0.068
1.165MetTyr: 1.165 ± 0.156
0.0MetXaa: 0.0 ± 0.0
Asn
4.127AsnAla: 4.127 ± 0.267
0.573AsnCys: 0.573 ± 0.122
3.19AsnAsp: 3.19 ± 0.235
3.668AsnGlu: 3.668 ± 0.283
2.751AsnPhe: 2.751 ± 0.203
4.49AsnGly: 4.49 ± 0.3
0.879AsnHis: 0.879 ± 0.128
4.375AsnIle: 4.375 ± 0.247
3.496AsnLys: 3.496 ± 0.282
4.795AsnLeu: 4.795 ± 0.258
1.643AsnMet: 1.643 ± 0.162
3.362AsnAsn: 3.362 ± 0.272
2.044AsnPro: 2.044 ± 0.184
1.643AsnGln: 1.643 ± 0.179
2.388AsnArg: 2.388 ± 0.221
3.401AsnSer: 3.401 ± 0.295
3.706AsnThr: 3.706 ± 0.37
3.974AsnVal: 3.974 ± 0.294
0.669AsnTrp: 0.669 ± 0.105
1.987AsnTyr: 1.987 ± 0.223
0.0AsnXaa: 0.0 ± 0.0
Pro
2.331ProAla: 2.331 ± 0.213
0.382ProCys: 0.382 ± 0.083
2.159ProAsp: 2.159 ± 0.222
3.19ProGlu: 3.19 ± 0.266
1.605ProPhe: 1.605 ± 0.178
2.407ProGly: 2.407 ± 0.217
0.726ProHis: 0.726 ± 0.115
2.579ProIle: 2.579 ± 0.218
2.617ProLys: 2.617 ± 0.231
2.465ProLeu: 2.465 ± 0.202
0.65ProMet: 0.65 ± 0.096
2.178ProAsn: 2.178 ± 0.19
1.146ProPro: 1.146 ± 0.163
1.165ProGln: 1.165 ± 0.153
1.395ProArg: 1.395 ± 0.145
2.216ProSer: 2.216 ± 0.202
2.331ProThr: 2.331 ± 0.18
2.522ProVal: 2.522 ± 0.178
0.611ProTrp: 0.611 ± 0.105
1.376ProTyr: 1.376 ± 0.15
0.0ProXaa: 0.0 ± 0.0
Gln
2.598GlnAla: 2.598 ± 0.227
0.21GlnCys: 0.21 ± 0.055
1.28GlnAsp: 1.28 ± 0.134
2.273GlnGlu: 2.273 ± 0.225
1.681GlnPhe: 1.681 ± 0.181
1.509GlnGly: 1.509 ± 0.16
0.535GlnHis: 0.535 ± 0.103
2.98GlnIle: 2.98 ± 0.238
2.044GlnLys: 2.044 ± 0.201
3.592GlnLeu: 3.592 ± 0.259
1.165GlnMet: 1.165 ± 0.146
1.815GlnAsn: 1.815 ± 0.188
1.299GlnPro: 1.299 ± 0.187
1.204GlnGln: 1.204 ± 0.136
1.528GlnArg: 1.528 ± 0.188
2.178GlnSer: 2.178 ± 0.18
2.159GlnThr: 2.159 ± 0.209
2.063GlnVal: 2.063 ± 0.22
0.439GlnTrp: 0.439 ± 0.09
1.968GlnTyr: 1.968 ± 0.198
0.0GlnXaa: 0.0 ± 0.0
Arg
3.057ArgAla: 3.057 ± 0.273
0.459ArgCys: 0.459 ± 0.089
2.942ArgAsp: 2.942 ± 0.243
2.789ArgGlu: 2.789 ± 0.247
2.216ArgPhe: 2.216 ± 0.223
2.235ArgGly: 2.235 ± 0.181
0.841ArgHis: 0.841 ± 0.113
3.534ArgIle: 3.534 ± 0.23
2.885ArgLys: 2.885 ± 0.209
3.057ArgLeu: 3.057 ± 0.257
1.165ArgMet: 1.165 ± 0.149
2.197ArgAsn: 2.197 ± 0.186
1.452ArgPro: 1.452 ± 0.164
1.7ArgGln: 1.7 ± 0.169
2.063ArgArg: 2.063 ± 0.227
2.522ArgSer: 2.522 ± 0.213
2.159ArgThr: 2.159 ± 0.222
3.152ArgVal: 3.152 ± 0.248
0.554ArgTrp: 0.554 ± 0.126
1.356ArgTyr: 1.356 ± 0.148
0.0ArgXaa: 0.0 ± 0.0
Ser
4.108SerAla: 4.108 ± 0.273
0.573SerCys: 0.573 ± 0.107
3.534SerAsp: 3.534 ± 0.257
4.127SerGlu: 4.127 ± 0.284
2.656SerPhe: 2.656 ± 0.23
4.432SerGly: 4.432 ± 0.484
1.223SerHis: 1.223 ± 0.142
5.044SerIle: 5.044 ± 0.389
4.738SerLys: 4.738 ± 0.313
4.834SerLeu: 4.834 ± 0.288
1.777SerMet: 1.777 ± 0.179
3.745SerAsn: 3.745 ± 0.306
2.082SerPro: 2.082 ± 0.233
2.121SerGln: 2.121 ± 0.181
2.999SerArg: 2.999 ± 0.236
4.26SerSer: 4.26 ± 0.295
4.165SerThr: 4.165 ± 0.29
4.031SerVal: 4.031 ± 0.277
0.802SerTrp: 0.802 ± 0.128
2.751SerTyr: 2.751 ± 0.217
0.0SerXaa: 0.0 ± 0.0
Thr
4.719ThrAla: 4.719 ± 0.433
0.822ThrCys: 0.822 ± 0.104
3.343ThrAsp: 3.343 ± 0.303
3.936ThrGlu: 3.936 ± 0.271
2.942ThrPhe: 2.942 ± 0.211
3.974ThrGly: 3.974 ± 0.398
1.242ThrHis: 1.242 ± 0.143
5.082ThrIle: 5.082 ± 0.336
2.942ThrLys: 2.942 ± 0.22
4.566ThrLeu: 4.566 ± 0.371
1.242ThrMet: 1.242 ± 0.169
3.63ThrAsn: 3.63 ± 0.303
3.057ThrPro: 3.057 ± 0.265
2.617ThrGln: 2.617 ± 0.23
2.426ThrArg: 2.426 ± 0.193
3.725ThrSer: 3.725 ± 0.332
3.936ThrThr: 3.936 ± 0.361
4.394ThrVal: 4.394 ± 0.313
0.974ThrTrp: 0.974 ± 0.144
2.407ThrTyr: 2.407 ± 0.231
0.0ThrXaa: 0.0 ± 0.0
Val
4.642ValAla: 4.642 ± 0.291
0.745ValCys: 0.745 ± 0.136
4.031ValAsp: 4.031 ± 0.301
4.49ValGlu: 4.49 ± 0.387
2.828ValPhe: 2.828 ± 0.247
3.458ValGly: 3.458 ± 0.26
1.299ValHis: 1.299 ± 0.139
4.719ValIle: 4.719 ± 0.285
5.349ValLys: 5.349 ± 0.315
4.738ValLeu: 4.738 ± 0.297
1.777ValMet: 1.777 ± 0.191
4.203ValAsn: 4.203 ± 0.274
2.273ValPro: 2.273 ± 0.194
2.484ValGln: 2.484 ± 0.244
2.732ValArg: 2.732 ± 0.267
4.108ValSer: 4.108 ± 0.278
3.706ValThr: 3.706 ± 0.3
4.738ValVal: 4.738 ± 0.345
0.726ValTrp: 0.726 ± 0.108
2.999ValTyr: 2.999 ± 0.23
0.0ValXaa: 0.0 ± 0.0
Trp
0.745TrpAla: 0.745 ± 0.112
0.21TrpCys: 0.21 ± 0.054
0.993TrpAsp: 0.993 ± 0.127
0.898TrpGlu: 0.898 ± 0.114
0.42TrpPhe: 0.42 ± 0.094
0.516TrpGly: 0.516 ± 0.114
0.325TrpHis: 0.325 ± 0.08
0.86TrpIle: 0.86 ± 0.119
1.108TrpLys: 1.108 ± 0.147
0.936TrpLeu: 0.936 ± 0.121
0.344TrpMet: 0.344 ± 0.073
0.535TrpAsn: 0.535 ± 0.101
0.516TrpPro: 0.516 ± 0.092
0.573TrpGln: 0.573 ± 0.109
0.516TrpArg: 0.516 ± 0.086
0.898TrpSer: 0.898 ± 0.117
0.936TrpThr: 0.936 ± 0.146
0.974TrpVal: 0.974 ± 0.132
0.248TrpTrp: 0.248 ± 0.069
0.497TrpTyr: 0.497 ± 0.087
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.465TyrAla: 2.465 ± 0.207
0.42TyrCys: 0.42 ± 0.091
2.828TyrAsp: 2.828 ± 0.262
2.77TyrGlu: 2.77 ± 0.224
1.624TyrPhe: 1.624 ± 0.16
2.484TyrGly: 2.484 ± 0.246
0.955TyrHis: 0.955 ± 0.137
2.923TyrIle: 2.923 ± 0.238
2.77TyrLys: 2.77 ± 0.19
3.152TyrLeu: 3.152 ± 0.294
0.783TyrMet: 0.783 ± 0.118
2.541TyrAsn: 2.541 ± 0.218
1.586TyrPro: 1.586 ± 0.142
1.089TyrGln: 1.089 ± 0.166
1.91TyrArg: 1.91 ± 0.188
2.789TyrSer: 2.789 ± 0.217
2.426TyrThr: 2.426 ± 0.259
2.789TyrVal: 2.789 ± 0.242
0.592TyrTrp: 0.592 ± 0.089
1.586TyrTyr: 1.586 ± 0.184
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 253 proteins (52344 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski