Amino acid dipepetide frequency for Propionimicrobium lymphophilum ACS-093-V-SCH5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.98AlaAla: 11.98 ± 0.165	1.067AlaCys: 1.067 ± 0.042	6.608AlaAsp: 6.608 ± 0.122	6.927AlaGlu: 6.927 ± 0.12	3.164AlaPhe: 3.164 ± 0.091	8.879AlaGly: 8.879 ± 0.147	1.741AlaHis: 1.741 ± 0.059	5.714AlaIle: 5.714 ± 0.109	5.912AlaLys: 5.912 ± 0.136	9.892AlaLeu: 9.892 ± 0.145	2.676AlaMet: 2.676 ± 0.067	3.439AlaAsn: 3.439 ± 0.076	4.24AlaPro: 4.24 ± 0.081	4.127AlaGln: 4.127 ± 0.106	5.962AlaArg: 5.962 ± 0.119	6.444AlaSer: 6.444 ± 0.103	5.582AlaThr: 5.582 ± 0.105	7.67AlaVal: 7.67 ± 0.115	1.449AlaTrp: 1.449 ± 0.061	2.239AlaTyr: 2.239 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.948CysAla: 0.948 ± 0.043	0.144CysCys: 0.144 ± 0.016	0.585CysAsp: 0.585 ± 0.035	0.579CysGlu: 0.579 ± 0.029	0.324CysPhe: 0.324 ± 0.021	1.073CysGly: 1.073 ± 0.044	0.199CysHis: 0.199 ± 0.017	0.375CysIle: 0.375 ± 0.026	0.308CysLys: 0.308 ± 0.02	0.847CysLeu: 0.847 ± 0.032	0.158CysMet: 0.158 ± 0.016	0.232CysAsn: 0.232 ± 0.02	0.558CysPro: 0.558 ± 0.037	0.336CysGln: 0.336 ± 0.024	0.528CysArg: 0.528 ± 0.029	0.627CysSer: 0.627 ± 0.036	0.415CysThr: 0.415 ± 0.026	0.764CysVal: 0.764 ± 0.036	0.148CysTrp: 0.148 ± 0.015	0.273CysTyr: 0.273 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	6.451AspAla: 6.451 ± 0.12	0.47AspCys: 0.47 ± 0.029	3.629AspAsp: 3.629 ± 0.094	5.239AspGlu: 5.239 ± 0.103	2.22AspPhe: 2.22 ± 0.061	5.063AspGly: 5.063 ± 0.098	1.101AspHis: 1.101 ± 0.043	2.811AspIle: 2.811 ± 0.067	2.557AspLys: 2.557 ± 0.069	5.884AspLeu: 5.884 ± 0.107	1.276AspMet: 1.276 ± 0.045	1.728AspAsn: 1.728 ± 0.045	3.423AspPro: 3.423 ± 0.084	2.208AspGln: 2.208 ± 0.049	3.182AspArg: 3.182 ± 0.089	3.576AspSer: 3.576 ± 0.082	2.617AspThr: 2.617 ± 0.07	4.748AspVal: 4.748 ± 0.092	0.994AspTrp: 0.994 ± 0.04	1.682AspTyr: 1.682 ± 0.055	0.0AspXaa: 0.0 ± 0.0
Glu	6.495GluAla: 6.495 ± 0.123	0.45GluCys: 0.45 ± 0.023	3.611GluAsp: 3.611 ± 0.074	4.267GluGlu: 4.267 ± 0.106	2.109GluPhe: 2.109 ± 0.057	4.254GluGly: 4.254 ± 0.084	1.313GluHis: 1.313 ± 0.046	3.935GluIle: 3.935 ± 0.076	3.56GluLys: 3.56 ± 0.071	6.943GluLeu: 6.943 ± 0.134	1.464GluMet: 1.464 ± 0.054	2.518GluAsn: 2.518 ± 0.058	2.773GluPro: 2.773 ± 0.069	2.677GluGln: 2.677 ± 0.079	3.837GluArg: 3.837 ± 0.084	3.256GluSer: 3.256 ± 0.068	3.318GluThr: 3.318 ± 0.071	4.827GluVal: 4.827 ± 0.083	0.781GluTrp: 0.781 ± 0.034	1.514GluTyr: 1.514 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	3.598PheAla: 3.598 ± 0.082	0.404PheCys: 0.404 ± 0.025	2.568PheAsp: 2.568 ± 0.063	2.104PheGlu: 2.104 ± 0.054	1.31PhePhe: 1.31 ± 0.051	3.466PheGly: 3.466 ± 0.073	0.539PheHis: 0.539 ± 0.033	1.533PheIle: 1.533 ± 0.057	1.348PheLys: 1.348 ± 0.042	2.746PheLeu: 2.746 ± 0.076	0.695PheMet: 0.695 ± 0.029	1.23PheAsn: 1.23 ± 0.042	1.315PhePro: 1.315 ± 0.045	0.89PheGln: 0.89 ± 0.038	1.502PheArg: 1.502 ± 0.041	2.623PheSer: 2.623 ± 0.074	2.034PheThr: 2.034 ± 0.061	2.773PheVal: 2.773 ± 0.063	0.482PheTrp: 0.482 ± 0.023	0.806PheTyr: 0.806 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	7.474GlyAla: 7.474 ± 0.13	0.885GlyCys: 0.885 ± 0.04	4.367GlyAsp: 4.367 ± 0.095	4.788GlyGlu: 4.788 ± 0.093	3.253GlyPhe: 3.253 ± 0.082	6.118GlyGly: 6.118 ± 0.134	1.517GlyHis: 1.517 ± 0.046	4.681GlyIle: 4.681 ± 0.088	4.414GlyLys: 4.414 ± 0.083	8.023GlyLeu: 8.023 ± 0.138	2.099GlyMet: 2.099 ± 0.052	2.51GlyAsn: 2.51 ± 0.068	2.94GlyPro: 2.94 ± 0.074	2.897GlyGln: 2.897 ± 0.073	4.537GlyArg: 4.537 ± 0.092	5.037GlySer: 5.037 ± 0.094	4.332GlyThr: 4.332 ± 0.1	6.709GlyVal: 6.709 ± 0.117	1.441GlyTrp: 1.441 ± 0.051	2.32GlyTyr: 2.32 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	1.608HisAla: 1.608 ± 0.054	0.171HisCys: 0.171 ± 0.015	1.125HisAsp: 1.125 ± 0.04	1.117HisGlu: 1.117 ± 0.036	0.541HisPhe: 0.541 ± 0.03	1.47HisGly: 1.47 ± 0.051	0.377HisHis: 0.377 ± 0.028	0.868HisIle: 0.868 ± 0.038	0.696HisLys: 0.696 ± 0.03	1.745HisLeu: 1.745 ± 0.052	0.437HisMet: 0.437 ± 0.028	0.576HisAsn: 0.576 ± 0.031	1.152HisPro: 1.152 ± 0.048	0.572HisGln: 0.572 ± 0.025	1.093HisArg: 1.093 ± 0.044	1.071HisSer: 1.071 ± 0.038	0.961HisThr: 0.961 ± 0.036	1.389HisVal: 1.389 ± 0.049	0.281HisTrp: 0.281 ± 0.02	0.484HisTyr: 0.484 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	6.302IleAla: 6.302 ± 0.109	0.708IleCys: 0.708 ± 0.033	3.936IleAsp: 3.936 ± 0.079	3.715IleGlu: 3.715 ± 0.084	1.968IlePhe: 1.968 ± 0.064	4.949IleGly: 4.949 ± 0.098	0.847IleHis: 0.847 ± 0.037	2.677IleIle: 2.677 ± 0.074	2.182IleLys: 2.182 ± 0.057	4.112IleLeu: 4.112 ± 0.089	0.98IleMet: 0.98 ± 0.04	1.953IleAsn: 1.953 ± 0.059	2.406IlePro: 2.406 ± 0.053	1.304IleGln: 1.304 ± 0.048	2.696IleArg: 2.696 ± 0.059	4.021IleSer: 4.021 ± 0.087	3.19IleThr: 3.19 ± 0.077	4.492IleVal: 4.492 ± 0.095	0.665IleTrp: 0.665 ± 0.033	1.263IleTyr: 1.263 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.125LysAla: 5.125 ± 0.118	0.321LysCys: 0.321 ± 0.024	2.61LysAsp: 2.61 ± 0.078	2.566LysGlu: 2.566 ± 0.074	1.397LysPhe: 1.397 ± 0.046	2.635LysGly: 2.635 ± 0.066	0.843LysHis: 0.843 ± 0.034	3.051LysIle: 3.051 ± 0.08	2.628LysLys: 2.628 ± 0.077	4.846LysLeu: 4.846 ± 0.081	1.304LysMet: 1.304 ± 0.044	1.882LysAsn: 1.882 ± 0.061	2.534LysPro: 2.534 ± 0.077	1.759LysGln: 1.759 ± 0.057	2.786LysArg: 2.786 ± 0.064	2.556LysSer: 2.556 ± 0.059	2.859LysThr: 2.859 ± 0.07	3.579LysVal: 3.579 ± 0.074	0.523LysTrp: 0.523 ± 0.031	1.187LysTyr: 1.187 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	11.573LeuAla: 11.573 ± 0.153	0.807LeuCys: 0.807 ± 0.033	6.129LeuAsp: 6.129 ± 0.109	5.657LeuGlu: 5.657 ± 0.101	3.017LeuPhe: 3.017 ± 0.084	7.941LeuGly: 7.941 ± 0.108	1.556LeuHis: 1.556 ± 0.048	5.331LeuIle: 5.331 ± 0.107	3.841LeuLys: 3.841 ± 0.076	8.979LeuLeu: 8.979 ± 0.178	1.904LeuMet: 1.904 ± 0.051	3.13LeuAsn: 3.13 ± 0.069	5.046LeuPro: 5.046 ± 0.09	2.45LeuGln: 2.45 ± 0.052	5.62LeuArg: 5.62 ± 0.1	6.643LeuSer: 6.643 ± 0.11	5.416LeuThr: 5.416 ± 0.093	7.782LeuVal: 7.782 ± 0.143	0.969LeuTrp: 0.969 ± 0.044	1.725LeuTyr: 1.725 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.616MetAla: 2.616 ± 0.064	0.204MetCys: 0.204 ± 0.017	1.038MetAsp: 1.038 ± 0.041	1.013MetGlu: 1.013 ± 0.041	0.766MetPhe: 0.766 ± 0.039	1.657MetGly: 1.657 ± 0.05	0.428MetHis: 0.428 ± 0.023	1.388MetIle: 1.388 ± 0.054	0.976MetLys: 0.976 ± 0.037	2.31MetLeu: 2.31 ± 0.069	0.566MetMet: 0.566 ± 0.035	0.901MetAsn: 0.901 ± 0.037	1.285MetPro: 1.285 ± 0.04	0.69MetGln: 0.69 ± 0.033	1.509MetArg: 1.509 ± 0.049	1.927MetSer: 1.927 ± 0.053	1.487MetThr: 1.487 ± 0.044	1.72MetVal: 1.72 ± 0.055	0.276MetTrp: 0.276 ± 0.02	0.394MetTyr: 0.394 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.198AsnAla: 3.198 ± 0.076	0.333AsnCys: 0.333 ± 0.023	1.87AsnAsp: 1.87 ± 0.055	2.056AsnGlu: 2.056 ± 0.058	1.199AsnPhe: 1.199 ± 0.049	2.764AsnGly: 2.764 ± 0.084	0.623AsnHis: 0.623 ± 0.026	1.663AsnIle: 1.663 ± 0.048	1.533AsnLys: 1.533 ± 0.052	3.097AsnLeu: 3.097 ± 0.07	0.825AsnMet: 0.825 ± 0.033	1.243AsnAsn: 1.243 ± 0.049	2.351AsnPro: 2.351 ± 0.066	1.279AsnGln: 1.279 ± 0.05	2.012AsnArg: 2.012 ± 0.055	2.122AsnSer: 2.122 ± 0.059	1.729AsnThr: 1.729 ± 0.052	2.418AsnVal: 2.418 ± 0.064	0.564AsnTrp: 0.564 ± 0.03	0.947AsnTyr: 0.947 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	5.002ProAla: 5.002 ± 0.112	0.3ProCys: 0.3 ± 0.02	3.375ProAsp: 3.375 ± 0.084	3.971ProGlu: 3.971 ± 0.076	1.446ProPhe: 1.446 ± 0.05	4.14ProGly: 4.14 ± 0.088	0.854ProHis: 0.854 ± 0.037	2.483ProIle: 2.483 ± 0.062	2.377ProLys: 2.377 ± 0.069	3.904ProLeu: 3.904 ± 0.083	0.944ProMet: 0.944 ± 0.039	1.646ProAsn: 1.646 ± 0.056	1.531ProPro: 1.531 ± 0.052	1.848ProGln: 1.848 ± 0.063	2.296ProArg: 2.296 ± 0.065	3.082ProSer: 3.082 ± 0.075	2.691ProThr: 2.691 ± 0.066	3.672ProVal: 3.672 ± 0.081	0.687ProTrp: 0.687 ± 0.032	1.099ProTyr: 1.099 ± 0.048	0.0ProXaa: 0.0 ± 0.0
Gln	4.081GlnAla: 4.081 ± 0.098	0.191GlnCys: 0.191 ± 0.016	1.517GlnAsp: 1.517 ± 0.044	1.94GlnGlu: 1.94 ± 0.058	0.976GlnPhe: 0.976 ± 0.04	2.08GlnGly: 2.08 ± 0.068	0.577GlnHis: 0.577 ± 0.03	2.436GlnIle: 2.436 ± 0.059	1.438GlnLys: 1.438 ± 0.052	3.97GlnLeu: 3.97 ± 0.089	0.917GlnMet: 0.917 ± 0.04	1.146GlnAsn: 1.146 ± 0.043	1.738GlnPro: 1.738 ± 0.069	1.521GlnGln: 1.521 ± 0.077	2.213GlnArg: 2.213 ± 0.066	1.8GlnSer: 1.8 ± 0.053	1.933GlnThr: 1.933 ± 0.059	2.973GlnVal: 2.973 ± 0.069	0.463GlnTrp: 0.463 ± 0.029	0.747GlnTyr: 0.747 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	5.447ArgAla: 5.447 ± 0.113	0.482ArgCys: 0.482 ± 0.032	3.209ArgAsp: 3.209 ± 0.08	3.586ArgGlu: 3.586 ± 0.088	2.028ArgPhe: 2.028 ± 0.059	3.982ArgGly: 3.982 ± 0.08	1.096ArgHis: 1.096 ± 0.042	3.262ArgIle: 3.262 ± 0.067	2.949ArgLys: 2.949 ± 0.077	5.663ArgLeu: 5.663 ± 0.115	1.631ArgMet: 1.631 ± 0.048	1.951ArgAsn: 1.951 ± 0.054	2.613ArgPro: 2.613 ± 0.066	2.304ArgGln: 2.304 ± 0.062	4.128ArgArg: 4.128 ± 0.091	3.335ArgSer: 3.335 ± 0.075	2.789ArgThr: 2.789 ± 0.063	4.347ArgVal: 4.347 ± 0.091	0.923ArgTrp: 0.923 ± 0.039	1.531ArgTyr: 1.531 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.536SerAla: 6.536 ± 0.108	0.598SerCys: 0.598 ± 0.031	3.87SerAsp: 3.87 ± 0.089	4.051SerGlu: 4.051 ± 0.081	2.208SerPhe: 2.208 ± 0.065	6.098SerGly: 6.098 ± 0.109	1.155SerHis: 1.155 ± 0.045	3.192SerIle: 3.192 ± 0.069	2.918SerLys: 2.918 ± 0.078	5.768SerLeu: 5.768 ± 0.09	1.577SerMet: 1.577 ± 0.045	2.093SerAsn: 2.093 ± 0.061	2.798SerPro: 2.798 ± 0.072	2.192SerGln: 2.192 ± 0.066	3.587SerArg: 3.587 ± 0.08	4.2SerSer: 4.2 ± 0.095	3.382SerThr: 3.382 ± 0.068	4.807SerVal: 4.807 ± 0.087	1.014SerTrp: 1.014 ± 0.047	1.635SerTyr: 1.635 ± 0.059	0.0SerXaa: 0.0 ± 0.0
Thr	5.309ThrAla: 5.309 ± 0.082	0.545ThrCys: 0.545 ± 0.032	3.331ThrAsp: 3.331 ± 0.079	2.918ThrGlu: 2.918 ± 0.067	1.917ThrPhe: 1.917 ± 0.061	4.772ThrGly: 4.772 ± 0.078	1.01ThrHis: 1.01 ± 0.035	3.124ThrIle: 3.124 ± 0.072	2.565ThrLys: 2.565 ± 0.058	5.009ThrLeu: 5.009 ± 0.093	1.196ThrMet: 1.196 ± 0.047	1.888ThrAsn: 1.888 ± 0.055	3.085ThrPro: 3.085 ± 0.072	1.844ThrGln: 1.844 ± 0.05	2.896ThrArg: 2.896 ± 0.063	3.501ThrSer: 3.501 ± 0.076	3.124ThrThr: 3.124 ± 0.081	4.415ThrVal: 4.415 ± 0.093	0.824ThrTrp: 0.824 ± 0.033	1.281ThrTyr: 1.281 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	8.33ValAla: 8.33 ± 0.121	0.95ValCys: 0.95 ± 0.036	5.125ValAsp: 5.125 ± 0.085	5.204ValGlu: 5.204 ± 0.098	2.713ValPhe: 2.713 ± 0.076	5.975ValGly: 5.975 ± 0.118	1.282ValHis: 1.282 ± 0.047	4.339ValIle: 4.339 ± 0.097	3.332ValLys: 3.332 ± 0.082	7.543ValLeu: 7.543 ± 0.12	1.72ValMet: 1.72 ± 0.053	2.534ValAsn: 2.534 ± 0.067	3.746ValPro: 3.746 ± 0.076	2.163ValGln: 2.163 ± 0.06	4.275ValArg: 4.275 ± 0.082	5.454ValSer: 5.454 ± 0.095	4.692ValThr: 4.692 ± 0.096	6.814ValVal: 6.814 ± 0.113	1.029ValTrp: 1.029 ± 0.042	1.643ValTyr: 1.643 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.398TrpAla: 1.398 ± 0.055	0.133TrpCys: 0.133 ± 0.014	0.736TrpAsp: 0.736 ± 0.036	0.608TrpGlu: 0.608 ± 0.034	0.561TrpPhe: 0.561 ± 0.034	0.985TrpGly: 0.985 ± 0.048	0.264TrpHis: 0.264 ± 0.019	0.643TrpIle: 0.643 ± 0.036	0.533TrpLys: 0.533 ± 0.034	1.769TrpLeu: 1.769 ± 0.057	0.339TrpMet: 0.339 ± 0.024	0.498TrpAsn: 0.498 ± 0.027	0.654TrpPro: 0.654 ± 0.032	0.703TrpGln: 0.703 ± 0.032	1.029TrpArg: 1.029 ± 0.049	0.86TrpSer: 0.86 ± 0.04	0.717TrpThr: 0.717 ± 0.034	1.133TrpVal: 1.133 ± 0.038	0.286TrpTrp: 0.286 ± 0.024	0.319TrpTyr: 0.319 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.242TyrAla: 2.242 ± 0.061	0.255TyrCys: 0.255 ± 0.022	1.622TyrAsp: 1.622 ± 0.045	1.596TyrGlu: 1.596 ± 0.047	0.847TyrPhe: 0.847 ± 0.037	2.043TyrGly: 2.043 ± 0.056	0.412TyrHis: 0.412 ± 0.025	0.863TyrIle: 0.863 ± 0.038	0.923TyrLys: 0.923 ± 0.036	2.466TyrLeu: 2.466 ± 0.061	0.443TyrMet: 0.443 ± 0.028	0.728TyrAsn: 0.728 ± 0.037	1.164TyrPro: 1.164 ± 0.041	0.892TyrGln: 0.892 ± 0.044	1.568TyrArg: 1.568 ± 0.048	1.543TyrSer: 1.543 ± 0.052	1.282TyrThr: 1.282 ± 0.048	1.83TyrVal: 1.83 ± 0.051	0.369TyrTrp: 0.369 ± 0.026	0.601TyrTyr: 0.601 ± 0.035	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2076 proteins (682374 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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