Amino acid dipepetide frequency for Bdellovibrio phage phiMH2K (Bacteriophage phiMH2K)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.16AlaAla: 7.16 ± 3.542
0.0AlaCys: 0.0 ± 0.0
1.193AlaAsp: 1.193 ± 0.841
4.177AlaGlu: 4.177 ± 1.187
2.387AlaPhe: 2.387 ± 0.684
4.177AlaGly: 4.177 ± 1.542
2.983AlaHis: 2.983 ± 1.553
4.773AlaIle: 4.773 ± 1.432
5.37AlaLys: 5.37 ± 1.918
4.177AlaLeu: 4.177 ± 1.75
1.79AlaMet: 1.79 ± 1.129
3.58AlaAsn: 3.58 ± 1.232
2.983AlaPro: 2.983 ± 1.397
2.983AlaGln: 2.983 ± 1.146
4.177AlaArg: 4.177 ± 0.99
4.177AlaSer: 4.177 ± 1.376
5.37AlaThr: 5.37 ± 1.769
2.387AlaVal: 2.387 ± 1.163
0.597AlaTrp: 0.597 ± 0.837
1.79AlaTyr: 1.79 ± 0.817
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.597CysAsp: 0.597 ± 0.728
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.193CysIle: 1.193 ± 1.091
0.597CysLys: 0.597 ± 0.774
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.597CysPro: 0.597 ± 0.898
0.0CysGln: 0.0 ± 0.0
1.79CysArg: 1.79 ± 1.021
0.597CysSer: 0.597 ± 0.774
0.0CysThr: 0.0 ± 0.0
0.597CysVal: 0.597 ± 0.625
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.387AspAla: 2.387 ± 0.942
0.0AspCys: 0.0 ± 0.0
3.58AspAsp: 3.58 ± 2.081
2.387AspGlu: 2.387 ± 1.295
4.773AspPhe: 4.773 ± 1.393
0.597AspGly: 0.597 ± 0.42
1.193AspHis: 1.193 ± 0.558
1.193AspIle: 1.193 ± 0.819
1.193AspLys: 1.193 ± 0.919
5.967AspLeu: 5.967 ± 1.539
0.597AspMet: 0.597 ± 0.652
2.387AspAsn: 2.387 ± 1.184
2.983AspPro: 2.983 ± 1.184
4.177AspGln: 4.177 ± 1.547
1.79AspArg: 1.79 ± 0.562
4.177AspSer: 4.177 ± 0.998
2.983AspThr: 2.983 ± 1.184
0.597AspVal: 0.597 ± 0.42
1.193AspTrp: 1.193 ± 0.558
3.58AspTyr: 3.58 ± 1.976
0.0AspXaa: 0.0 ± 0.0
Glu
2.387GluAla: 2.387 ± 1.839
0.597GluCys: 0.597 ± 0.728
1.79GluAsp: 1.79 ± 1.084
0.597GluGlu: 0.597 ± 0.563
1.79GluPhe: 1.79 ± 1.021
0.0GluGly: 0.0 ± 0.0
1.79GluHis: 1.79 ± 0.71
3.58GluIle: 3.58 ± 2.523
5.967GluLys: 5.967 ± 2.638
7.16GluLeu: 7.16 ± 2.491
1.79GluMet: 1.79 ± 0.682
2.983GluAsn: 2.983 ± 1.126
0.597GluPro: 0.597 ± 0.728
2.387GluGln: 2.387 ± 0.942
2.387GluArg: 2.387 ± 0.91
2.387GluSer: 2.387 ± 0.726
5.37GluThr: 5.37 ± 3.052
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
3.58GluTyr: 3.58 ± 1.286
0.0GluXaa: 0.0 ± 0.0
Phe
2.983PheAla: 2.983 ± 1.013
0.0PheCys: 0.0 ± 0.0
3.58PheAsp: 3.58 ± 1.057
1.193PheGlu: 1.193 ± 0.581
1.79PhePhe: 1.79 ± 1.261
5.967PheGly: 5.967 ± 1.893
1.193PheHis: 1.193 ± 1.09
5.37PheIle: 5.37 ± 1.727
1.79PheLys: 1.79 ± 0.833
2.387PheLeu: 2.387 ± 1.461
0.0PheMet: 0.0 ± 0.421
3.58PheAsn: 3.58 ± 1.649
0.597PhePro: 0.597 ± 0.545
2.387PheGln: 2.387 ± 1.176
3.58PheArg: 3.58 ± 1.976
2.983PheSer: 2.983 ± 0.77
2.983PheThr: 2.983 ± 1.114
1.193PheVal: 1.193 ± 0.841
1.193PheTrp: 1.193 ± 0.841
1.79PheTyr: 1.79 ± 0.955
0.0PheXaa: 0.0 ± 0.0
Gly
2.387GlyAla: 2.387 ± 1.163
0.0GlyCys: 0.0 ± 0.0
3.58GlyAsp: 3.58 ± 1.169
3.58GlyGlu: 3.58 ± 1.096
2.983GlyPhe: 2.983 ± 1.057
5.967GlyGly: 5.967 ± 1.898
0.597GlyHis: 0.597 ± 0.837
2.387GlyIle: 2.387 ± 1.242
4.177GlyLys: 4.177 ± 1.393
4.773GlyLeu: 4.773 ± 2.014
1.193GlyMet: 1.193 ± 0.581
5.37GlyAsn: 5.37 ± 2.753
2.983GlyPro: 2.983 ± 1.045
5.967GlyGln: 5.967 ± 1.821
0.597GlyArg: 0.597 ± 0.42
2.387GlySer: 2.387 ± 1.2
4.773GlyThr: 4.773 ± 1.304
1.79GlyVal: 1.79 ± 0.957
0.0GlyTrp: 0.0 ± 0.0
2.387GlyTyr: 2.387 ± 1.184
0.0GlyXaa: 0.0 ± 0.0
His
1.193HisAla: 1.193 ± 0.558
1.193HisCys: 1.193 ± 0.798
1.193HisAsp: 1.193 ± 0.558
2.387HisGlu: 2.387 ± 1.278
1.79HisPhe: 1.79 ± 1.261
2.387HisGly: 2.387 ± 1.088
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.387HisLys: 2.387 ± 2.158
3.58HisLeu: 3.58 ± 1.443
0.597HisMet: 0.597 ± 0.728
1.193HisAsn: 1.193 ± 0.558
1.79HisPro: 1.79 ± 1.216
1.193HisGln: 1.193 ± 1.096
0.0HisArg: 0.0 ± 0.0
2.387HisSer: 2.387 ± 1.29
1.79HisThr: 1.79 ± 0.955
1.79HisVal: 1.79 ± 0.845
0.597HisTrp: 0.597 ± 0.545
1.193HisTyr: 1.193 ± 0.941
0.0HisXaa: 0.0 ± 0.0
Ile
1.79IleAla: 1.79 ± 0.844
0.0IleCys: 0.0 ± 0.0
3.58IleAsp: 3.58 ± 1.046
3.58IleGlu: 3.58 ± 0.845
2.387IlePhe: 2.387 ± 1.117
4.773IleGly: 4.773 ± 1.742
0.597IleHis: 0.597 ± 0.545
0.0IleIle: 0.0 ± 0.0
2.983IleLys: 2.983 ± 1.167
4.177IleLeu: 4.177 ± 1.843
0.0IleMet: 0.0 ± 0.0
4.177IleAsn: 4.177 ± 0.981
4.773IlePro: 4.773 ± 0.896
1.193IleGln: 1.193 ± 1.286
4.177IleArg: 4.177 ± 1.552
2.983IleSer: 2.983 ± 0.808
4.177IleThr: 4.177 ± 1.496
1.193IleVal: 1.193 ± 0.819
0.0IleTrp: 0.0 ± 0.0
2.387IleTyr: 2.387 ± 1.293
0.0IleXaa: 0.0 ± 0.0
Lys
5.37LysAla: 5.37 ± 1.103
1.193LysCys: 1.193 ± 0.919
1.79LysAsp: 1.79 ± 0.71
4.177LysGlu: 4.177 ± 1.409
5.37LysPhe: 5.37 ± 1.25
1.79LysGly: 1.79 ± 1.261
2.387LysHis: 2.387 ± 1.45
3.58LysIle: 3.58 ± 0.961
6.563LysLys: 6.563 ± 3.24
7.757LysLeu: 7.757 ± 3.005
0.597LysMet: 0.597 ± 0.42
4.773LysAsn: 4.773 ± 2.845
4.177LysPro: 4.177 ± 1.334
1.79LysGln: 1.79 ± 0.904
4.773LysArg: 4.773 ± 2.651
5.967LysSer: 5.967 ± 1.941
4.773LysThr: 4.773 ± 1.142
2.387LysVal: 2.387 ± 1.229
1.79LysTrp: 1.79 ± 1.092
1.193LysTyr: 1.193 ± 0.807
0.0LysXaa: 0.0 ± 0.0
Leu
8.353LeuAla: 8.353 ± 1.517
0.597LeuCys: 0.597 ± 0.898
4.177LeuAsp: 4.177 ± 1.555
1.79LeuGlu: 1.79 ± 0.844
1.79LeuPhe: 1.79 ± 1.12
5.37LeuGly: 5.37 ± 0.921
1.193LeuHis: 1.193 ± 0.854
4.773LeuIle: 4.773 ± 1.711
7.757LeuLys: 7.757 ± 2.098
4.177LeuLeu: 4.177 ± 2.011
4.177LeuMet: 4.177 ± 1.979
7.757LeuAsn: 7.757 ± 2.008
4.773LeuPro: 4.773 ± 1.231
6.563LeuGln: 6.563 ± 2.052
4.773LeuArg: 4.773 ± 2.597
5.967LeuSer: 5.967 ± 2.479
5.37LeuThr: 5.37 ± 2.124
2.983LeuVal: 2.983 ± 1.064
1.193LeuTrp: 1.193 ± 0.807
0.597LeuTyr: 0.597 ± 0.837
0.0LeuXaa: 0.0 ± 0.0
Met
2.983MetAla: 2.983 ± 0.995
0.0MetCys: 0.0 ± 0.0
1.193MetAsp: 1.193 ± 0.698
2.387MetGlu: 2.387 ± 1.081
0.0MetPhe: 0.0 ± 0.0
0.597MetGly: 0.597 ± 0.774
0.597MetHis: 0.597 ± 0.545
0.0MetIle: 0.0 ± 0.0
1.79MetLys: 1.79 ± 1.129
1.79MetLeu: 1.79 ± 1.392
2.387MetMet: 2.387 ± 1.303
1.193MetAsn: 1.193 ± 0.808
1.193MetPro: 1.193 ± 0.581
2.983MetGln: 2.983 ± 0.928
1.193MetArg: 1.193 ± 1.213
1.79MetSer: 1.79 ± 0.884
0.0MetThr: 0.0 ± 0.0
1.79MetVal: 1.79 ± 0.682
1.193MetTrp: 1.193 ± 0.558
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.177AsnAla: 4.177 ± 1.221
0.0AsnCys: 0.0 ± 0.0
2.387AsnAsp: 2.387 ± 0.726
1.193AsnGlu: 1.193 ± 0.819
2.983AsnPhe: 2.983 ± 0.94
5.967AsnGly: 5.967 ± 1.16
2.983AsnHis: 2.983 ± 1.22
2.387AsnIle: 2.387 ± 1.296
2.983AsnLys: 2.983 ± 1.602
5.37AsnLeu: 5.37 ± 1.975
1.79AsnMet: 1.79 ± 0.824
1.79AsnAsn: 1.79 ± 1.124
1.79AsnPro: 1.79 ± 1.013
2.983AsnGln: 2.983 ± 1.201
5.967AsnArg: 5.967 ± 2.512
5.967AsnSer: 5.967 ± 2.829
4.177AsnThr: 4.177 ± 1.367
1.79AsnVal: 1.79 ± 1.327
1.79AsnTrp: 1.79 ± 0.944
1.79AsnTyr: 1.79 ± 1.291
0.0AsnXaa: 0.0 ± 0.0
Pro
4.177ProAla: 4.177 ± 2.19
1.79ProCys: 1.79 ± 1.021
2.983ProAsp: 2.983 ± 1.057
3.58ProGlu: 3.58 ± 1.427
1.79ProPhe: 1.79 ± 0.937
1.79ProGly: 1.79 ± 1.261
2.387ProHis: 2.387 ± 0.784
5.37ProIle: 5.37 ± 2.093
2.387ProLys: 2.387 ± 1.155
2.387ProLeu: 2.387 ± 1.225
1.79ProMet: 1.79 ± 1.13
3.58ProAsn: 3.58 ± 1.051
1.79ProPro: 1.79 ± 1.626
5.967ProGln: 5.967 ± 1.754
1.79ProArg: 1.79 ± 0.981
4.773ProSer: 4.773 ± 1.629
2.983ProThr: 2.983 ± 1.422
2.387ProVal: 2.387 ± 0.896
0.597ProTrp: 0.597 ± 0.42
1.193ProTyr: 1.193 ± 0.558
0.0ProXaa: 0.0 ± 0.0
Gln
4.773GlnAla: 4.773 ± 1.753
0.0GlnCys: 0.0 ± 0.0
2.387GlnAsp: 2.387 ± 1.019
3.58GlnGlu: 3.58 ± 1.458
2.387GlnPhe: 2.387 ± 1.052
4.177GlnGly: 4.177 ± 1.228
1.193GlnHis: 1.193 ± 0.648
1.79GlnIle: 1.79 ± 0.805
3.58GlnLys: 3.58 ± 2.03
4.773GlnLeu: 4.773 ± 1.421
2.387GlnMet: 2.387 ± 1.254
5.37GlnAsn: 5.37 ± 3.098
0.597GlnPro: 0.597 ± 0.774
4.773GlnGln: 4.773 ± 1.988
3.58GlnArg: 3.58 ± 2.227
4.773GlnSer: 4.773 ± 2.555
7.16GlnThr: 7.16 ± 1.713
3.58GlnVal: 3.58 ± 1.649
0.597GlnTrp: 0.597 ± 0.545
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.387ArgAla: 2.387 ± 0.951
0.0ArgCys: 0.0 ± 0.0
2.983ArgAsp: 2.983 ± 1.123
2.387ArgGlu: 2.387 ± 1.637
1.79ArgPhe: 1.79 ± 0.894
3.58ArgGly: 3.58 ± 1.564
0.597ArgHis: 0.597 ± 0.42
1.193ArgIle: 1.193 ± 1.096
4.773ArgLys: 4.773 ± 2.283
5.967ArgLeu: 5.967 ± 1.351
1.193ArgMet: 1.193 ± 0.808
1.193ArgAsn: 1.193 ± 0.92
6.563ArgPro: 6.563 ± 1.749
2.983ArgGln: 2.983 ± 0.996
2.983ArgArg: 2.983 ± 2.837
7.16ArgSer: 7.16 ± 4.034
4.177ArgThr: 4.177 ± 3.681
1.193ArgVal: 1.193 ± 0.885
1.193ArgTrp: 1.193 ± 0.794
2.387ArgTyr: 2.387 ± 1.117
0.0ArgXaa: 0.0 ± 0.0
Ser
4.773SerAla: 4.773 ± 1.25
0.597SerCys: 0.597 ± 0.774
2.983SerAsp: 2.983 ± 1.167
5.967SerGlu: 5.967 ± 2.938
3.58SerPhe: 3.58 ± 1.094
2.387SerGly: 2.387 ± 0.968
1.79SerHis: 1.79 ± 1.017
2.983SerIle: 2.983 ± 1.153
7.16SerLys: 7.16 ± 3.21
7.757SerLeu: 7.757 ± 2.553
0.597SerMet: 0.597 ± 0.839
5.37SerAsn: 5.37 ± 3.196
2.983SerPro: 2.983 ± 1.492
4.177SerGln: 4.177 ± 2.236
5.37SerArg: 5.37 ± 2.216
4.177SerSer: 4.177 ± 1.357
7.16SerThr: 7.16 ± 2.742
1.193SerVal: 1.193 ± 0.558
0.0SerTrp: 0.0 ± 0.0
1.79SerTyr: 1.79 ± 0.967
0.0SerXaa: 0.0 ± 0.0
Thr
4.773ThrAla: 4.773 ± 1.787
0.0ThrCys: 0.0 ± 0.0
2.983ThrAsp: 2.983 ± 1.306
1.193ThrGlu: 1.193 ± 0.807
5.37ThrPhe: 5.37 ± 1.863
5.37ThrGly: 5.37 ± 1.995
2.387ThrHis: 2.387 ± 0.916
4.177ThrIle: 4.177 ± 2.2
6.563ThrLys: 6.563 ± 2.092
4.773ThrLeu: 4.773 ± 3.219
1.79ThrMet: 1.79 ± 1.33
3.58ThrAsn: 3.58 ± 1.657
6.563ThrPro: 6.563 ± 2.827
2.983ThrGln: 2.983 ± 1.325
5.967ThrArg: 5.967 ± 2.023
8.353ThrSer: 8.353 ± 4.481
10.74ThrThr: 10.74 ± 5.508
2.387ThrVal: 2.387 ± 1.569
0.0ThrTrp: 0.0 ± 0.0
2.387ThrTyr: 2.387 ± 1.184
0.0ThrXaa: 0.0 ± 0.0
Val
2.983ValAla: 2.983 ± 1.089
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
2.387ValGlu: 2.387 ± 1.21
0.597ValPhe: 0.597 ± 0.625
0.0ValGly: 0.0 ± 0.0
1.79ValHis: 1.79 ± 0.944
2.387ValIle: 2.387 ± 1.601
3.58ValLys: 3.58 ± 1.4
2.387ValLeu: 2.387 ± 1.095
0.597ValMet: 0.597 ± 0.42
0.597ValAsn: 0.597 ± 0.728
4.177ValPro: 4.177 ± 2.362
1.79ValGln: 1.79 ± 1.161
0.597ValArg: 0.597 ± 0.42
0.0ValSer: 0.0 ± 0.0
5.967ValThr: 5.967 ± 1.217
1.79ValVal: 1.79 ± 0.824
1.79ValTrp: 1.79 ± 0.844
1.79ValTyr: 1.79 ± 1.216
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.79TrpAsp: 1.79 ± 0.824
0.597TrpGlu: 0.597 ± 0.42
1.193TrpPhe: 1.193 ± 0.841
0.0TrpGly: 0.0 ± 0.0
1.193TrpHis: 1.193 ± 0.558
1.193TrpIle: 1.193 ± 1.091
0.0TrpLys: 0.0 ± 0.0
1.193TrpLeu: 1.193 ± 1.091
0.597TrpMet: 0.597 ± 0.545
0.0TrpAsn: 0.0 ± 0.0
1.79TrpPro: 1.79 ± 0.944
1.193TrpGln: 1.193 ± 1.126
0.0TrpArg: 0.0 ± 0.0
0.597TrpSer: 0.597 ± 0.42
1.193TrpThr: 1.193 ± 0.807
0.597TrpVal: 0.597 ± 0.42
0.597TrpTrp: 0.597 ± 0.774
0.597TrpTyr: 0.597 ± 0.545
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.193TyrAla: 1.193 ± 0.558
0.0TyrCys: 0.0 ± 0.0
2.983TyrAsp: 2.983 ± 1.115
0.0TyrGlu: 0.0 ± 0.0
2.387TyrPhe: 2.387 ± 1.2
2.983TyrGly: 2.983 ± 0.917
1.79TyrHis: 1.79 ± 1.636
0.597TyrIle: 0.597 ± 0.652
0.597TyrLys: 0.597 ± 0.545
3.58TyrLeu: 3.58 ± 2.244
0.597TyrMet: 0.597 ± 0.545
1.79TyrAsn: 1.79 ± 1.012
1.79TyrPro: 1.79 ± 0.824
2.983TyrGln: 2.983 ± 1.14
1.193TyrArg: 1.193 ± 0.558
1.193TyrSer: 1.193 ± 0.941
1.193TyrThr: 1.193 ± 0.558
3.58TyrVal: 3.58 ± 1.675
0.0TyrTrp: 0.0 ± 0.0
0.597TyrTyr: 0.597 ± 0.545
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (1677 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski