Amino acid dipepetide frequency for Facklamia tabacinasalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.537AlaAla: 4.537 ± 0.106
0.361AlaCys: 0.361 ± 0.024
3.81AlaAsp: 3.81 ± 0.082
4.828AlaGlu: 4.828 ± 0.093
3.01AlaPhe: 3.01 ± 0.067
4.701AlaGly: 4.701 ± 0.093
1.231AlaHis: 1.231 ± 0.037
6.049AlaIle: 6.049 ± 0.098
3.969AlaLys: 3.969 ± 0.076
6.901AlaLeu: 6.901 ± 0.102
2.067AlaMet: 2.067 ± 0.061
3.349AlaAsn: 3.349 ± 0.076
1.932AlaPro: 1.932 ± 0.061
2.876AlaGln: 2.876 ± 0.083
2.557AlaArg: 2.557 ± 0.064
4.18AlaSer: 4.18 ± 0.083
4.011AlaThr: 4.011 ± 0.076
4.72AlaVal: 4.72 ± 0.104
0.518AlaTrp: 0.518 ± 0.027
2.534AlaTyr: 2.534 ± 0.06
0.0AlaXaa: 0.0 ± 0.0
Cys
0.254CysAla: 0.254 ± 0.019
0.033CysCys: 0.033 ± 0.006
0.233CysAsp: 0.233 ± 0.017
0.244CysGlu: 0.244 ± 0.02
0.229CysPhe: 0.229 ± 0.019
0.406CysGly: 0.406 ± 0.028
0.15CysHis: 0.15 ± 0.017
0.366CysIle: 0.366 ± 0.025
0.169CysLys: 0.169 ± 0.015
0.366CysLeu: 0.366 ± 0.024
0.099CysMet: 0.099 ± 0.01
0.15CysAsn: 0.15 ± 0.014
0.18CysPro: 0.18 ± 0.018
0.19CysGln: 0.19 ± 0.018
0.186CysArg: 0.186 ± 0.015
0.263CysSer: 0.263 ± 0.02
0.209CysThr: 0.209 ± 0.018
0.216CysVal: 0.216 ± 0.018
0.031CysTrp: 0.031 ± 0.006
0.141CysTyr: 0.141 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
3.964AspAla: 3.964 ± 0.079
0.219AspCys: 0.219 ± 0.019
3.404AspAsp: 3.404 ± 0.138
5.307AspGlu: 5.307 ± 0.11
2.913AspPhe: 2.913 ± 0.073
3.657AspGly: 3.657 ± 0.073
1.046AspHis: 1.046 ± 0.041
5.21AspIle: 5.21 ± 0.093
3.227AspLys: 3.227 ± 0.083
5.618AspLeu: 5.618 ± 0.081
1.555AspMet: 1.555 ± 0.045
2.967AspAsn: 2.967 ± 0.06
1.858AspPro: 1.858 ± 0.062
2.229AspGln: 2.229 ± 0.053
2.242AspArg: 2.242 ± 0.054
3.475AspSer: 3.475 ± 0.072
3.183AspThr: 3.183 ± 0.066
4.222AspVal: 4.222 ± 0.081
0.713AspTrp: 0.713 ± 0.039
3.031AspTyr: 3.031 ± 0.07
0.0AspXaa: 0.0 ± 0.0
Glu
6.316GluAla: 6.316 ± 0.134
0.263GluCys: 0.263 ± 0.022
4.949GluAsp: 4.949 ± 0.087
7.778GluGlu: 7.778 ± 0.168
3.086GluPhe: 3.086 ± 0.065
4.394GluGly: 4.394 ± 0.09
1.461GluHis: 1.461 ± 0.045
5.802GluIle: 5.802 ± 0.098
4.668GluLys: 4.668 ± 0.096
7.837GluLeu: 7.837 ± 0.119
2.155GluMet: 2.155 ± 0.056
4.185GluAsn: 4.185 ± 0.073
2.084GluPro: 2.084 ± 0.063
3.224GluGln: 3.224 ± 0.078
3.163GluArg: 3.163 ± 0.071
4.776GluSer: 4.776 ± 0.108
4.468GluThr: 4.468 ± 0.087
5.747GluVal: 5.747 ± 0.098
0.758GluTrp: 0.758 ± 0.039
2.76GluTyr: 2.76 ± 0.062
0.0GluXaa: 0.0 ± 0.0
Phe
2.815PheAla: 2.815 ± 0.068
0.193PheCys: 0.193 ± 0.016
2.974PheAsp: 2.974 ± 0.068
3.231PheGlu: 3.231 ± 0.07
1.965PhePhe: 1.965 ± 0.063
3.079PheGly: 3.079 ± 0.069
0.673PheHis: 0.673 ± 0.031
3.765PheIle: 3.765 ± 0.077
2.53PheLys: 2.53 ± 0.056
3.687PheLeu: 3.687 ± 0.089
1.113PheMet: 1.113 ± 0.039
2.682PheAsn: 2.682 ± 0.064
1.393PhePro: 1.393 ± 0.044
1.52PheGln: 1.52 ± 0.042
1.458PheArg: 1.458 ± 0.046
3.051PheSer: 3.051 ± 0.075
2.629PheThr: 2.629 ± 0.069
2.92PheVal: 2.92 ± 0.069
0.396PheTrp: 0.396 ± 0.024
1.697PheTyr: 1.697 ± 0.054
0.0PheXaa: 0.0 ± 0.0
Gly
4.327GlyAla: 4.327 ± 0.087
0.301GlyCys: 0.301 ± 0.021
3.414GlyAsp: 3.414 ± 0.078
4.542GlyGlu: 4.542 ± 0.088
3.079GlyPhe: 3.079 ± 0.072
4.365GlyGly: 4.365 ± 0.11
1.347GlyHis: 1.347 ± 0.043
5.398GlyIle: 5.398 ± 0.103
3.773GlyLys: 3.773 ± 0.085
6.19GlyLeu: 6.19 ± 0.102
1.887GlyMet: 1.887 ± 0.055
2.754GlyAsn: 2.754 ± 0.061
1.498GlyPro: 1.498 ± 0.044
2.46GlyGln: 2.46 ± 0.058
2.48GlyArg: 2.48 ± 0.075
3.813GlySer: 3.813 ± 0.076
3.649GlyThr: 3.649 ± 0.078
4.898GlyVal: 4.898 ± 0.088
0.626GlyTrp: 0.626 ± 0.029
2.783GlyTyr: 2.783 ± 0.067
0.0GlyXaa: 0.0 ± 0.0
His
1.137HisAla: 1.137 ± 0.033
0.143HisCys: 0.143 ± 0.014
1.092HisAsp: 1.092 ± 0.044
1.306HisGlu: 1.306 ± 0.047
1.007HisPhe: 1.007 ± 0.038
1.234HisGly: 1.234 ± 0.045
0.522HisHis: 0.522 ± 0.035
1.471HisIle: 1.471 ± 0.045
0.904HisLys: 0.904 ± 0.04
1.877HisLeu: 1.877 ± 0.055
0.403HisMet: 0.403 ± 0.021
0.889HisAsn: 0.889 ± 0.037
0.941HisPro: 0.941 ± 0.043
0.831HisGln: 0.831 ± 0.036
0.865HisArg: 0.865 ± 0.037
1.175HisSer: 1.175 ± 0.04
1.06HisThr: 1.06 ± 0.036
1.123HisVal: 1.123 ± 0.042
0.179HisTrp: 0.179 ± 0.017
0.95HisTyr: 0.95 ± 0.036
0.0HisXaa: 0.0 ± 0.0
Ile
6.031IleAla: 6.031 ± 0.093
0.386IleCys: 0.386 ± 0.023
5.331IleAsp: 5.331 ± 0.096
6.557IleGlu: 6.557 ± 0.098
3.208IlePhe: 3.208 ± 0.074
5.591IleGly: 5.591 ± 0.094
1.587IleHis: 1.587 ± 0.044
6.645IleIle: 6.645 ± 0.125
4.408IleLys: 4.408 ± 0.086
7.039IleLeu: 7.039 ± 0.117
1.87IleMet: 1.87 ± 0.055
4.363IleAsn: 4.363 ± 0.081
3.2IlePro: 3.2 ± 0.069
3.314IleGln: 3.314 ± 0.071
3.008IleArg: 3.008 ± 0.064
4.887IleSer: 4.887 ± 0.085
4.395IleThr: 4.395 ± 0.085
5.703IleVal: 5.703 ± 0.089
0.561IleTrp: 0.561 ± 0.032
2.784IleTyr: 2.784 ± 0.066
0.0IleXaa: 0.0 ± 0.0
Lys
4.055LysAla: 4.055 ± 0.091
0.173LysCys: 0.173 ± 0.015
3.67LysAsp: 3.67 ± 0.076
5.564LysGlu: 5.564 ± 0.102
1.868LysPhe: 1.868 ± 0.058
3.12LysGly: 3.12 ± 0.078
1.221LysHis: 1.221 ± 0.044
3.89LysIle: 3.89 ± 0.074
3.779LysLys: 3.779 ± 0.094
4.993LysLeu: 4.993 ± 0.094
1.613LysMet: 1.613 ± 0.05
2.898LysAsn: 2.898 ± 0.075
1.817LysPro: 1.817 ± 0.058
2.773LysGln: 2.773 ± 0.069
2.636LysArg: 2.636 ± 0.06
3.208LysSer: 3.208 ± 0.062
2.926LysThr: 2.926 ± 0.064
4.042LysVal: 4.042 ± 0.086
0.488LysTrp: 0.488 ± 0.029
2.314LysTyr: 2.314 ± 0.061
0.0LysXaa: 0.0 ± 0.0
Leu
6.931LeuAla: 6.931 ± 0.109
0.38LeuCys: 0.38 ± 0.023
5.717LeuAsp: 5.717 ± 0.085
7.101LeuGlu: 7.101 ± 0.107
4.246LeuPhe: 4.246 ± 0.091
5.951LeuGly: 5.951 ± 0.106
1.371LeuHis: 1.371 ± 0.039
7.631LeuIle: 7.631 ± 0.127
5.521LeuLys: 5.521 ± 0.092
8.955LeuLeu: 8.955 ± 0.153
2.571LeuMet: 2.571 ± 0.065
5.444LeuAsn: 5.444 ± 0.098
3.561LeuPro: 3.561 ± 0.075
2.957LeuGln: 2.957 ± 0.07
3.397LeuArg: 3.397 ± 0.075
7.034LeuSer: 7.034 ± 0.108
5.906LeuThr: 5.906 ± 0.086
6.288LeuVal: 6.288 ± 0.103
0.707LeuTrp: 0.707 ± 0.037
3.118LeuTyr: 3.118 ± 0.073
0.0LeuXaa: 0.0 ± 0.0
Met
1.84MetAla: 1.84 ± 0.054
0.082MetCys: 0.082 ± 0.011
1.553MetAsp: 1.553 ± 0.048
1.63MetGlu: 1.63 ± 0.045
0.927MetPhe: 0.927 ± 0.04
1.637MetGly: 1.637 ± 0.057
0.396MetHis: 0.396 ± 0.024
2.121MetIle: 2.121 ± 0.045
1.861MetLys: 1.861 ± 0.046
2.239MetLeu: 2.239 ± 0.051
0.728MetMet: 0.728 ± 0.03
1.75MetAsn: 1.75 ± 0.049
0.978MetPro: 0.978 ± 0.036
0.92MetGln: 0.92 ± 0.038
1.15MetArg: 1.15 ± 0.046
1.908MetSer: 1.908 ± 0.047
1.871MetThr: 1.871 ± 0.051
1.648MetVal: 1.648 ± 0.049
0.135MetTrp: 0.135 ± 0.015
0.819MetTyr: 0.819 ± 0.033
0.0MetXaa: 0.0 ± 0.0
Asn
3.157AsnAla: 3.157 ± 0.072
0.19AsnCys: 0.19 ± 0.017
3.091AsnAsp: 3.091 ± 0.066
4.11AsnGlu: 4.11 ± 0.086
2.155AsnPhe: 2.155 ± 0.06
3.228AsnGly: 3.228 ± 0.071
1.31AsnHis: 1.31 ± 0.042
4.15AsnIle: 4.15 ± 0.09
3.137AsnLys: 3.137 ± 0.077
4.712AsnLeu: 4.712 ± 0.082
1.354AsnMet: 1.354 ± 0.043
3.071AsnAsn: 3.071 ± 0.076
2.334AsnPro: 2.334 ± 0.056
2.601AsnGln: 2.601 ± 0.07
2.266AsnArg: 2.266 ± 0.058
2.882AsnSer: 2.882 ± 0.07
2.717AsnThr: 2.717 ± 0.058
3.279AsnVal: 3.279 ± 0.07
0.548AsnTrp: 0.548 ± 0.028
2.315AsnTyr: 2.315 ± 0.066
0.0AsnXaa: 0.0 ± 0.0
Pro
2.101ProAla: 2.101 ± 0.065
0.097ProCys: 0.097 ± 0.012
2.039ProAsp: 2.039 ± 0.056
3.264ProGlu: 3.264 ± 0.068
1.553ProPhe: 1.553 ± 0.052
1.99ProGly: 1.99 ± 0.057
0.659ProHis: 0.659 ± 0.03
2.835ProIle: 2.835 ± 0.066
1.875ProLys: 1.875 ± 0.055
3.005ProLeu: 3.005 ± 0.073
0.86ProMet: 0.86 ± 0.033
1.914ProAsn: 1.914 ± 0.058
0.623ProPro: 0.623 ± 0.033
1.123ProGln: 1.123 ± 0.043
1.039ProArg: 1.039 ± 0.035
2.158ProSer: 2.158 ± 0.053
2.206ProThr: 2.206 ± 0.056
2.537ProVal: 2.537 ± 0.069
0.304ProTrp: 0.304 ± 0.022
1.282ProTyr: 1.282 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
3.399GlnAla: 3.399 ± 0.086
0.121GlnCys: 0.121 ± 0.014
2.033GlnAsp: 2.033 ± 0.06
3.23GlnGlu: 3.23 ± 0.072
1.769GlnPhe: 1.769 ± 0.046
2.159GlnGly: 2.159 ± 0.056
0.767GlnHis: 0.767 ± 0.03
3.169GlnIle: 3.169 ± 0.069
2.029GlnLys: 2.029 ± 0.054
4.387GlnLeu: 4.387 ± 0.091
1.078GlnMet: 1.078 ± 0.037
1.787GlnAsn: 1.787 ± 0.053
1.34GlnPro: 1.34 ± 0.043
1.82GlnGln: 1.82 ± 0.06
1.77GlnArg: 1.77 ± 0.058
2.509GlnSer: 2.509 ± 0.072
2.386GlnThr: 2.386 ± 0.055
2.778GlnVal: 2.778 ± 0.066
0.392GlnTrp: 0.392 ± 0.024
1.505GlnTyr: 1.505 ± 0.054
0.0GlnXaa: 0.0 ± 0.0
Arg
2.135ArgAla: 2.135 ± 0.061
0.156ArgCys: 0.156 ± 0.013
2.103ArgAsp: 2.103 ± 0.055
3.2ArgGlu: 3.2 ± 0.075
1.861ArgPhe: 1.861 ± 0.053
2.193ArgGly: 2.193 ± 0.057
0.796ArgHis: 0.796 ± 0.035
3.169ArgIle: 3.169 ± 0.068
2.567ArgLys: 2.567 ± 0.071
3.998ArgLeu: 3.998 ± 0.093
1.041ArgMet: 1.041 ± 0.039
1.959ArgAsn: 1.959 ± 0.065
1.259ArgPro: 1.259 ± 0.046
1.787ArgGln: 1.787 ± 0.052
1.938ArgArg: 1.938 ± 0.059
2.094ArgSer: 2.094 ± 0.053
2.063ArgThr: 2.063 ± 0.061
2.572ArgVal: 2.572 ± 0.069
0.359ArgTrp: 0.359 ± 0.021
1.682ArgTyr: 1.682 ± 0.054
0.0ArgXaa: 0.0 ± 0.0
Ser
3.727SerAla: 3.727 ± 0.07
0.227SerCys: 0.227 ± 0.02
3.782SerAsp: 3.782 ± 0.079
4.884SerGlu: 4.884 ± 0.1
2.878SerPhe: 2.878 ± 0.062
4.374SerGly: 4.374 ± 0.094
1.241SerHis: 1.241 ± 0.046
5.051SerIle: 5.051 ± 0.09
3.528SerLys: 3.528 ± 0.081
6.092SerLeu: 6.092 ± 0.115
1.582SerMet: 1.582 ± 0.044
3.309SerAsn: 3.309 ± 0.078
1.868SerPro: 1.868 ± 0.059
2.811SerGln: 2.811 ± 0.064
2.352SerArg: 2.352 ± 0.059
3.982SerSer: 3.982 ± 0.102
3.465SerThr: 3.465 ± 0.072
4.371SerVal: 4.371 ± 0.069
0.571SerTrp: 0.571 ± 0.031
2.436SerTyr: 2.436 ± 0.061
0.0SerXaa: 0.0 ± 0.0
Thr
3.639ThrAla: 3.639 ± 0.079
0.199ThrCys: 0.199 ± 0.018
3.424ThrAsp: 3.424 ± 0.071
4.268ThrGlu: 4.268 ± 0.091
2.558ThrPhe: 2.558 ± 0.059
3.903ThrGly: 3.903 ± 0.072
1.166ThrHis: 1.166 ± 0.044
4.82ThrIle: 4.82 ± 0.081
2.963ThrLys: 2.963 ± 0.067
5.609ThrLeu: 5.609 ± 0.097
1.312ThrMet: 1.312 ± 0.044
2.929ThrAsn: 2.929 ± 0.062
2.385ThrPro: 2.385 ± 0.071
2.273ThrGln: 2.273 ± 0.064
2.012ThrArg: 2.012 ± 0.052
3.464ThrSer: 3.464 ± 0.082
3.302ThrThr: 3.302 ± 0.082
4.286ThrVal: 4.286 ± 0.092
0.501ThrTrp: 0.501 ± 0.03
2.28ThrTyr: 2.28 ± 0.07
0.0ThrXaa: 0.0 ± 0.0
Val
4.931ValAla: 4.931 ± 0.088
0.315ValCys: 0.315 ± 0.025
4.387ValAsp: 4.387 ± 0.085
5.547ValGlu: 5.547 ± 0.098
2.977ValPhe: 2.977 ± 0.071
4.651ValGly: 4.651 ± 0.1
1.078ValHis: 1.078 ± 0.04
5.782ValIle: 5.782 ± 0.098
3.766ValLys: 3.766 ± 0.079
6.288ValLeu: 6.288 ± 0.098
1.84ValMet: 1.84 ± 0.052
3.566ValAsn: 3.566 ± 0.079
2.484ValPro: 2.484 ± 0.064
2.382ValGln: 2.382 ± 0.059
2.402ValArg: 2.402 ± 0.064
4.675ValSer: 4.675 ± 0.1
4.235ValThr: 4.235 ± 0.079
5.223ValVal: 5.223 ± 0.102
0.51ValTrp: 0.51 ± 0.027
2.433ValTyr: 2.433 ± 0.062
0.0ValXaa: 0.0 ± 0.0
Trp
0.467TrpAla: 0.467 ± 0.028
0.043TrpCys: 0.043 ± 0.008
0.545TrpAsp: 0.545 ± 0.04
0.578TrpGlu: 0.578 ± 0.032
0.426TrpPhe: 0.426 ± 0.026
0.541TrpGly: 0.541 ± 0.029
0.194TrpHis: 0.194 ± 0.015
0.691TrpIle: 0.691 ± 0.035
0.453TrpLys: 0.453 ± 0.024
1.096TrpLeu: 1.096 ± 0.046
0.263TrpMet: 0.263 ± 0.018
0.547TrpAsn: 0.547 ± 0.03
0.254TrpPro: 0.254 ± 0.019
0.436TrpGln: 0.436 ± 0.025
0.335TrpArg: 0.335 ± 0.023
0.486TrpSer: 0.486 ± 0.028
0.442TrpThr: 0.442 ± 0.024
0.548TrpVal: 0.548 ± 0.026
0.099TrpTrp: 0.099 ± 0.011
0.304TrpTyr: 0.304 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.379TyrAla: 2.379 ± 0.061
0.234TyrCys: 0.234 ± 0.021
2.489TyrAsp: 2.489 ± 0.064
2.706TyrGlu: 2.706 ± 0.061
2.057TyrPhe: 2.057 ± 0.046
2.409TyrGly: 2.409 ± 0.068
0.892TyrHis: 0.892 ± 0.038
2.852TyrIle: 2.852 ± 0.069
1.919TyrLys: 1.919 ± 0.056
3.901TyrLeu: 3.901 ± 0.1
0.804TyrMet: 0.804 ± 0.033
2.095TyrAsn: 2.095 ± 0.054
1.474TyrPro: 1.474 ± 0.052
1.9TyrGln: 1.9 ± 0.056
1.677TyrArg: 1.677 ± 0.048
2.511TyrSer: 2.511 ± 0.055
2.168TyrThr: 2.168 ± 0.059
2.35TyrVal: 2.35 ± 0.063
0.351TyrTrp: 0.351 ± 0.023
1.827TyrTyr: 1.827 ± 0.053
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2319 proteins (704389 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski