Amino acid dipepetide frequency for Pseudomonas phage 201phi2-1 (Pseudomonas chlororaphis phage 201phi2-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.766AlaAla: 5.766 ± 0.459
0.666AlaCys: 0.666 ± 0.092
4.362AlaAsp: 4.362 ± 0.31
4.867AlaGlu: 4.867 ± 0.243
2.504AlaPhe: 2.504 ± 0.171
4.473AlaGly: 4.473 ± 0.405
1.313AlaHis: 1.313 ± 0.113
4.534AlaIle: 4.534 ± 0.221
4.574AlaLys: 4.574 ± 0.258
6.079AlaLeu: 6.079 ± 0.262
2.413AlaMet: 2.413 ± 0.186
3.898AlaAsn: 3.898 ± 0.19
2.333AlaPro: 2.333 ± 0.141
2.747AlaGln: 2.747 ± 0.191
3.544AlaArg: 3.544 ± 0.213
3.756AlaSer: 3.756 ± 0.192
4.695AlaThr: 4.695 ± 0.252
4.807AlaVal: 4.807 ± 0.288
0.838AlaTrp: 0.838 ± 0.092
3.12AlaTyr: 3.12 ± 0.201
0.0AlaXaa: 0.0 ± 0.0
Cys
0.656CysAla: 0.656 ± 0.087
0.111CysCys: 0.111 ± 0.031
0.717CysAsp: 0.717 ± 0.092
0.717CysGlu: 0.717 ± 0.081
0.283CysPhe: 0.283 ± 0.055
0.576CysGly: 0.576 ± 0.077
0.232CysHis: 0.232 ± 0.057
0.636CysIle: 0.636 ± 0.093
0.535CysLys: 0.535 ± 0.068
0.656CysLeu: 0.656 ± 0.083
0.283CysMet: 0.283 ± 0.056
0.464CysAsn: 0.464 ± 0.064
0.374CysPro: 0.374 ± 0.059
0.323CysGln: 0.323 ± 0.058
0.717CysArg: 0.717 ± 0.091
0.454CysSer: 0.454 ± 0.068
0.565CysThr: 0.565 ± 0.075
0.747CysVal: 0.747 ± 0.09
0.192CysTrp: 0.192 ± 0.044
0.545CysTyr: 0.545 ± 0.07
0.0CysXaa: 0.0 ± 0.0
Asp
4.493AspAla: 4.493 ± 0.214
0.636AspCys: 0.636 ± 0.08
4.393AspAsp: 4.393 ± 0.251
4.514AspGlu: 4.514 ± 0.283
2.848AspPhe: 2.848 ± 0.13
4.776AspGly: 4.776 ± 0.277
1.293AspHis: 1.293 ± 0.104
4.201AspIle: 4.201 ± 0.212
2.989AspLys: 2.989 ± 0.209
6.17AspLeu: 6.17 ± 0.238
1.666AspMet: 1.666 ± 0.141
2.888AspAsn: 2.888 ± 0.158
3.534AspPro: 3.534 ± 0.183
2.585AspGln: 2.585 ± 0.16
3.09AspArg: 3.09 ± 0.18
3.161AspSer: 3.161 ± 0.197
3.999AspThr: 3.999 ± 0.257
4.605AspVal: 4.605 ± 0.252
1.111AspTrp: 1.111 ± 0.088
2.595AspTyr: 2.595 ± 0.171
0.0AspXaa: 0.0 ± 0.0
Glu
5.412GluAla: 5.412 ± 0.3
0.798GluCys: 0.798 ± 0.098
3.696GluAsp: 3.696 ± 0.242
3.908GluGlu: 3.908 ± 0.321
3.15GluPhe: 3.15 ± 0.164
3.676GluGly: 3.676 ± 0.237
1.585GluHis: 1.585 ± 0.131
3.979GluIle: 3.979 ± 0.225
2.736GluLys: 2.736 ± 0.182
6.917GluLeu: 6.917 ± 0.268
1.807GluMet: 1.807 ± 0.139
2.434GluAsn: 2.434 ± 0.162
2.535GluPro: 2.535 ± 0.187
2.827GluGln: 2.827 ± 0.18
3.645GluArg: 3.645 ± 0.219
3.645GluSer: 3.645 ± 0.206
3.787GluThr: 3.787 ± 0.232
4.655GluVal: 4.655 ± 0.224
1.131GluTrp: 1.131 ± 0.124
2.969GluTyr: 2.969 ± 0.147
0.0GluXaa: 0.0 ± 0.0
Phe
2.403PheAla: 2.403 ± 0.187
0.434PheCys: 0.434 ± 0.068
3.352PheAsp: 3.352 ± 0.198
2.949PheGlu: 2.949 ± 0.195
1.525PhePhe: 1.525 ± 0.12
2.736PheGly: 2.736 ± 0.199
0.879PheHis: 0.879 ± 0.095
2.565PheIle: 2.565 ± 0.176
2.938PheLys: 2.938 ± 0.193
2.716PheLeu: 2.716 ± 0.159
0.969PheMet: 0.969 ± 0.111
2.595PheAsn: 2.595 ± 0.168
1.636PhePro: 1.636 ± 0.115
1.242PheGln: 1.242 ± 0.105
1.908PheArg: 1.908 ± 0.122
1.999PheSer: 1.999 ± 0.134
2.555PheThr: 2.555 ± 0.174
2.565PheVal: 2.565 ± 0.161
0.535PheTrp: 0.535 ± 0.065
1.696PheTyr: 1.696 ± 0.147
0.0PheXaa: 0.0 ± 0.0
Gly
3.565GlyAla: 3.565 ± 0.243
0.666GlyCys: 0.666 ± 0.084
4.11GlyAsp: 4.11 ± 0.253
4.362GlyGlu: 4.362 ± 0.206
2.898GlyPhe: 2.898 ± 0.19
4.413GlyGly: 4.413 ± 0.327
1.161GlyHis: 1.161 ± 0.11
4.211GlyIle: 4.211 ± 0.202
3.837GlyLys: 3.837 ± 0.273
5.241GlyLeu: 5.241 ± 0.207
1.676GlyMet: 1.676 ± 0.132
3.585GlyAsn: 3.585 ± 0.227
2.333GlyPro: 2.333 ± 0.193
2.535GlyGln: 2.535 ± 0.218
3.171GlyArg: 3.171 ± 0.196
3.817GlySer: 3.817 ± 0.209
4.413GlyThr: 4.413 ± 0.436
4.554GlyVal: 4.554 ± 0.215
1.08GlyTrp: 1.08 ± 0.117
2.999GlyTyr: 2.999 ± 0.206
0.0GlyXaa: 0.0 ± 0.0
His
1.111HisAla: 1.111 ± 0.121
0.283HisCys: 0.283 ± 0.058
1.282HisAsp: 1.282 ± 0.108
1.101HisGlu: 1.101 ± 0.109
0.949HisPhe: 0.949 ± 0.09
1.404HisGly: 1.404 ± 0.111
0.545HisHis: 0.545 ± 0.074
1.505HisIle: 1.505 ± 0.15
1.02HisLys: 1.02 ± 0.103
1.888HisLeu: 1.888 ± 0.143
0.707HisMet: 0.707 ± 0.085
1.08HisAsn: 1.08 ± 0.099
1.212HisPro: 1.212 ± 0.124
0.798HisGln: 0.798 ± 0.089
1.222HisArg: 1.222 ± 0.124
1.192HisSer: 1.192 ± 0.104
1.313HisThr: 1.313 ± 0.105
1.515HisVal: 1.515 ± 0.12
0.485HisTrp: 0.485 ± 0.078
1.05HisTyr: 1.05 ± 0.115
0.0HisXaa: 0.0 ± 0.0
Ile
4.433IleAla: 4.433 ± 0.242
0.535IleCys: 0.535 ± 0.075
5.17IleAsp: 5.17 ± 0.24
4.433IleGlu: 4.433 ± 0.215
1.565IlePhe: 1.565 ± 0.149
3.443IleGly: 3.443 ± 0.183
1.525IleHis: 1.525 ± 0.128
3.039IleIle: 3.039 ± 0.17
3.928IleLys: 3.928 ± 0.223
4.292IleLeu: 4.292 ± 0.253
1.393IleMet: 1.393 ± 0.116
3.251IleAsn: 3.251 ± 0.206
3.262IlePro: 3.262 ± 0.189
2.514IleGln: 2.514 ± 0.162
3.322IleArg: 3.322 ± 0.157
3.665IleSer: 3.665 ± 0.207
4.433IleThr: 4.433 ± 0.219
4.191IleVal: 4.191 ± 0.209
0.757IleTrp: 0.757 ± 0.085
2.03IleTyr: 2.03 ± 0.136
0.0IleXaa: 0.0 ± 0.0
Lys
4.938LysAla: 4.938 ± 0.257
0.555LysCys: 0.555 ± 0.081
3.716LysAsp: 3.716 ± 0.21
3.554LysGlu: 3.554 ± 0.203
2.393LysPhe: 2.393 ± 0.152
3.888LysGly: 3.888 ± 0.27
1.383LysHis: 1.383 ± 0.123
2.615LysIle: 2.615 ± 0.159
2.363LysLys: 2.363 ± 0.195
5.422LysLeu: 5.422 ± 0.226
1.626LysMet: 1.626 ± 0.129
1.949LysAsn: 1.949 ± 0.147
2.555LysPro: 2.555 ± 0.16
1.919LysGln: 1.919 ± 0.143
3.191LysArg: 3.191 ± 0.205
2.878LysSer: 2.878 ± 0.183
3.171LysThr: 3.171 ± 0.14
4.483LysVal: 4.483 ± 0.213
0.778LysTrp: 0.778 ± 0.098
2.121LysTyr: 2.121 ± 0.156
0.0LysXaa: 0.0 ± 0.0
Leu
6.109LeuAla: 6.109 ± 0.244
0.879LeuCys: 0.879 ± 0.093
5.503LeuAsp: 5.503 ± 0.269
5.776LeuGlu: 5.776 ± 0.26
3.352LeuPhe: 3.352 ± 0.189
5.614LeuGly: 5.614 ± 0.248
1.908LeuHis: 1.908 ± 0.121
4.887LeuIle: 4.887 ± 0.221
5.493LeuLys: 5.493 ± 0.238
6.362LeuLeu: 6.362 ± 0.284
2.494LeuMet: 2.494 ± 0.154
4.978LeuAsn: 4.978 ± 0.224
4.069LeuPro: 4.069 ± 0.259
2.858LeuGln: 2.858 ± 0.157
4.17LeuArg: 4.17 ± 0.211
4.736LeuSer: 4.736 ± 0.21
5.826LeuThr: 5.826 ± 0.226
5.564LeuVal: 5.564 ± 0.247
0.909LeuTrp: 0.909 ± 0.091
3.07LeuTyr: 3.07 ± 0.184
0.0LeuXaa: 0.0 ± 0.0
Met
2.686MetAla: 2.686 ± 0.189
0.364MetCys: 0.364 ± 0.056
1.848MetAsp: 1.848 ± 0.134
1.686MetGlu: 1.686 ± 0.136
1.111MetPhe: 1.111 ± 0.104
1.787MetGly: 1.787 ± 0.164
0.636MetHis: 0.636 ± 0.082
1.636MetIle: 1.636 ± 0.123
1.474MetLys: 1.474 ± 0.149
2.05MetLeu: 2.05 ± 0.141
0.757MetMet: 0.757 ± 0.075
1.192MetAsn: 1.192 ± 0.099
0.868MetPro: 0.868 ± 0.083
1.192MetGln: 1.192 ± 0.117
1.575MetArg: 1.575 ± 0.127
2.272MetSer: 2.272 ± 0.155
2.04MetThr: 2.04 ± 0.127
2.07MetVal: 2.07 ± 0.15
0.293MetTrp: 0.293 ± 0.06
1.02MetTyr: 1.02 ± 0.104
0.0MetXaa: 0.0 ± 0.0
Asn
3.464AsnAla: 3.464 ± 0.205
0.384AsnCys: 0.384 ± 0.07
3.201AsnAsp: 3.201 ± 0.181
2.949AsnGlu: 2.949 ± 0.184
1.807AsnPhe: 1.807 ± 0.132
4.1AsnGly: 4.1 ± 0.292
1.091AsnHis: 1.091 ± 0.105
3.09AsnIle: 3.09 ± 0.177
2.636AsnLys: 2.636 ± 0.174
3.847AsnLeu: 3.847 ± 0.183
1.313AsnMet: 1.313 ± 0.115
2.242AsnAsn: 2.242 ± 0.173
2.777AsnPro: 2.777 ± 0.162
2.08AsnGln: 2.08 ± 0.157
2.747AsnArg: 2.747 ± 0.159
2.454AsnSer: 2.454 ± 0.171
3.14AsnThr: 3.14 ± 0.171
3.383AsnVal: 3.383 ± 0.205
0.889AsnTrp: 0.889 ± 0.091
2.282AsnTyr: 2.282 ± 0.148
0.0AsnXaa: 0.0 ± 0.0
Pro
3.181ProAla: 3.181 ± 0.2
0.303ProCys: 0.303 ± 0.056
3.171ProAsp: 3.171 ± 0.187
3.817ProGlu: 3.817 ± 0.193
1.828ProPhe: 1.828 ± 0.141
2.535ProGly: 2.535 ± 0.195
1.0ProHis: 1.0 ± 0.107
2.565ProIle: 2.565 ± 0.176
2.504ProLys: 2.504 ± 0.178
3.13ProLeu: 3.13 ± 0.168
1.272ProMet: 1.272 ± 0.109
2.413ProAsn: 2.413 ± 0.17
1.424ProPro: 1.424 ± 0.141
1.444ProGln: 1.444 ± 0.133
1.919ProArg: 1.919 ± 0.134
2.524ProSer: 2.524 ± 0.138
3.191ProThr: 3.191 ± 0.201
3.272ProVal: 3.272 ± 0.219
0.525ProTrp: 0.525 ± 0.078
1.777ProTyr: 1.777 ± 0.133
0.0ProXaa: 0.0 ± 0.0
Gln
3.171GlnAla: 3.171 ± 0.247
0.364GlnCys: 0.364 ± 0.067
1.595GlnAsp: 1.595 ± 0.13
1.919GlnGlu: 1.919 ± 0.151
1.828GlnPhe: 1.828 ± 0.13
2.262GlnGly: 2.262 ± 0.222
0.737GlnHis: 0.737 ± 0.087
2.393GlnIle: 2.393 ± 0.167
1.434GlnLys: 1.434 ± 0.127
4.15GlnLeu: 4.15 ± 0.212
1.192GlnMet: 1.192 ± 0.099
1.616GlnAsn: 1.616 ± 0.134
1.666GlnPro: 1.666 ± 0.147
1.676GlnGln: 1.676 ± 0.15
2.222GlnArg: 2.222 ± 0.149
2.252GlnSer: 2.252 ± 0.155
2.211GlnThr: 2.211 ± 0.163
2.878GlnVal: 2.878 ± 0.169
0.666GlnTrp: 0.666 ± 0.09
1.747GlnTyr: 1.747 ± 0.136
0.0GlnXaa: 0.0 ± 0.0
Arg
3.13ArgAla: 3.13 ± 0.179
0.404ArgCys: 0.404 ± 0.073
3.241ArgAsp: 3.241 ± 0.196
3.211ArgGlu: 3.211 ± 0.195
2.04ArgPhe: 2.04 ± 0.148
3.11ArgGly: 3.11 ± 0.176
1.313ArgHis: 1.313 ± 0.116
3.272ArgIle: 3.272 ± 0.177
3.322ArgLys: 3.322 ± 0.212
4.877ArgLeu: 4.877 ± 0.245
1.707ArgMet: 1.707 ± 0.122
2.434ArgAsn: 2.434 ± 0.192
2.07ArgPro: 2.07 ± 0.137
1.969ArgGln: 1.969 ± 0.139
2.908ArgArg: 2.908 ± 0.174
2.807ArgSer: 2.807 ± 0.178
2.868ArgThr: 2.868 ± 0.171
3.837ArgVal: 3.837 ± 0.241
0.909ArgTrp: 0.909 ± 0.092
2.474ArgTyr: 2.474 ± 0.181
0.0ArgXaa: 0.0 ± 0.0
Ser
3.878SerAla: 3.878 ± 0.245
0.505SerCys: 0.505 ± 0.077
3.393SerAsp: 3.393 ± 0.188
3.494SerGlu: 3.494 ± 0.186
2.504SerPhe: 2.504 ± 0.136
3.635SerGly: 3.635 ± 0.207
1.06SerHis: 1.06 ± 0.129
3.797SerIle: 3.797 ± 0.2
3.312SerLys: 3.312 ± 0.201
4.483SerLeu: 4.483 ± 0.262
1.767SerMet: 1.767 ± 0.154
3.05SerAsn: 3.05 ± 0.18
2.333SerPro: 2.333 ± 0.158
1.969SerGln: 1.969 ± 0.148
2.393SerArg: 2.393 ± 0.157
2.989SerSer: 2.989 ± 0.185
3.898SerThr: 3.898 ± 0.188
4.332SerVal: 4.332 ± 0.214
0.788SerTrp: 0.788 ± 0.109
1.979SerTyr: 1.979 ± 0.134
0.0SerXaa: 0.0 ± 0.0
Thr
4.281ThrAla: 4.281 ± 0.229
0.505ThrCys: 0.505 ± 0.084
3.968ThrAsp: 3.968 ± 0.226
4.029ThrGlu: 4.029 ± 0.282
2.817ThrPhe: 2.817 ± 0.172
4.584ThrGly: 4.584 ± 0.258
1.293ThrHis: 1.293 ± 0.129
4.271ThrIle: 4.271 ± 0.201
3.191ThrLys: 3.191 ± 0.184
5.695ThrLeu: 5.695 ± 0.265
1.555ThrMet: 1.555 ± 0.133
3.181ThrAsn: 3.181 ± 0.202
3.403ThrPro: 3.403 ± 0.178
2.504ThrGln: 2.504 ± 0.192
3.12ThrArg: 3.12 ± 0.192
3.312ThrSer: 3.312 ± 0.19
3.817ThrThr: 3.817 ± 0.223
5.008ThrVal: 5.008 ± 0.209
0.929ThrTrp: 0.929 ± 0.096
2.878ThrTyr: 2.878 ± 0.23
0.0ThrXaa: 0.0 ± 0.0
Val
4.988ValAla: 4.988 ± 0.277
0.626ValCys: 0.626 ± 0.083
5.271ValAsp: 5.271 ± 0.246
4.887ValGlu: 4.887 ± 0.244
2.434ValPhe: 2.434 ± 0.176
4.221ValGly: 4.221 ± 0.226
1.333ValHis: 1.333 ± 0.124
4.493ValIle: 4.493 ± 0.21
4.615ValLys: 4.615 ± 0.227
5.099ValLeu: 5.099 ± 0.211
2.302ValMet: 2.302 ± 0.157
3.625ValAsn: 3.625 ± 0.191
3.13ValPro: 3.13 ± 0.161
2.514ValGln: 2.514 ± 0.128
3.756ValArg: 3.756 ± 0.207
4.382ValSer: 4.382 ± 0.197
5.069ValThr: 5.069 ± 0.227
5.513ValVal: 5.513 ± 0.235
1.04ValTrp: 1.04 ± 0.109
2.898ValTyr: 2.898 ± 0.159
0.0ValXaa: 0.0 ± 0.0
Trp
0.969TrpAla: 0.969 ± 0.106
0.252TrpCys: 0.252 ± 0.054
0.949TrpAsp: 0.949 ± 0.109
0.707TrpGlu: 0.707 ± 0.086
0.646TrpPhe: 0.646 ± 0.09
0.919TrpGly: 0.919 ± 0.106
0.384TrpHis: 0.384 ± 0.073
0.788TrpIle: 0.788 ± 0.078
0.616TrpLys: 0.616 ± 0.073
1.737TrpLeu: 1.737 ± 0.177
0.555TrpMet: 0.555 ± 0.083
0.707TrpAsn: 0.707 ± 0.085
0.475TrpPro: 0.475 ± 0.072
0.485TrpGln: 0.485 ± 0.079
0.818TrpArg: 0.818 ± 0.076
0.838TrpSer: 0.838 ± 0.101
0.798TrpThr: 0.798 ± 0.092
1.414TrpVal: 1.414 ± 0.13
0.151TrpTrp: 0.151 ± 0.042
0.444TrpTyr: 0.444 ± 0.066
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.656TyrAla: 2.656 ± 0.163
0.515TyrCys: 0.515 ± 0.074
2.605TyrAsp: 2.605 ± 0.132
2.413TyrGlu: 2.413 ± 0.165
1.717TyrPhe: 1.717 ± 0.135
2.474TyrGly: 2.474 ± 0.174
0.99TyrHis: 0.99 ± 0.122
2.716TyrIle: 2.716 ± 0.177
1.979TyrLys: 1.979 ± 0.139
3.746TyrLeu: 3.746 ± 0.203
1.091TyrMet: 1.091 ± 0.107
2.292TyrAsn: 2.292 ± 0.153
1.807TyrPro: 1.807 ± 0.145
1.797TyrGln: 1.797 ± 0.176
2.464TyrArg: 2.464 ± 0.161
2.423TyrSer: 2.423 ± 0.158
2.555TyrThr: 2.555 ± 0.176
2.807TyrVal: 2.807 ± 0.183
0.646TyrTrp: 0.646 ± 0.085
1.818TyrTyr: 1.818 ± 0.152
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 461 proteins (99033 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski