Amino acid dipepetide frequency for Neonectria ditissima

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.568AlaAla: 9.568 ± 0.084	1.169AlaCys: 1.169 ± 0.02	4.59AlaAsp: 4.59 ± 0.03	5.254AlaGlu: 5.254 ± 0.048	3.258AlaPhe: 3.258 ± 0.023	5.939AlaGly: 5.939 ± 0.038	1.819AlaHis: 1.819 ± 0.019	4.343AlaIle: 4.343 ± 0.035	4.15AlaLys: 4.15 ± 0.034	7.952AlaLeu: 7.952 ± 0.041	2.067AlaMet: 2.067 ± 0.02	2.919AlaAsn: 2.919 ± 0.024	4.976AlaPro: 4.976 ± 0.036	3.409AlaGln: 3.409 ± 0.03	5.009AlaArg: 5.009 ± 0.03	7.489AlaSer: 7.489 ± 0.041	5.503AlaThr: 5.503 ± 0.035	5.808AlaVal: 5.808 ± 0.033	1.289AlaTrp: 1.289 ± 0.015	2.151AlaTyr: 2.151 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.99CysAla: 0.99 ± 0.017	0.242CysCys: 0.242 ± 0.007	0.725CysAsp: 0.725 ± 0.014	0.621CysGlu: 0.621 ± 0.012	0.568CysPhe: 0.568 ± 0.01	0.997CysGly: 0.997 ± 0.025	0.345CysHis: 0.345 ± 0.008	0.719CysIle: 0.719 ± 0.015	0.526CysLys: 0.526 ± 0.01	1.348CysLeu: 1.348 ± 0.033	0.267CysMet: 0.267 ± 0.006	0.44CysAsn: 0.44 ± 0.009	0.695CysPro: 0.695 ± 0.012	0.473CysGln: 0.473 ± 0.013	0.776CysArg: 0.776 ± 0.014	0.96CysSer: 0.96 ± 0.027	0.765CysThr: 0.765 ± 0.046	0.855CysVal: 0.855 ± 0.015	0.214CysTrp: 0.214 ± 0.006	0.344CysTyr: 0.344 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.148AspAla: 5.148 ± 0.036	0.706AspCys: 0.706 ± 0.039	4.827AspAsp: 4.827 ± 0.044	4.605AspGlu: 4.605 ± 0.036	2.309AspPhe: 2.309 ± 0.02	4.394AspGly: 4.394 ± 0.031	1.291AspHis: 1.291 ± 0.017	2.979AspIle: 2.979 ± 0.025	2.491AspLys: 2.491 ± 0.024	5.225AspLeu: 5.225 ± 0.032	1.337AspMet: 1.337 ± 0.018	1.891AspAsn: 1.891 ± 0.02	3.356AspPro: 3.356 ± 0.027	1.959AspGln: 1.959 ± 0.019	3.099AspArg: 3.099 ± 0.027	4.337AspSer: 4.337 ± 0.032	3.019AspThr: 3.019 ± 0.027	3.935AspVal: 3.935 ± 0.028	0.959AspTrp: 0.959 ± 0.014	1.585AspTyr: 1.585 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.589GluAla: 5.589 ± 0.049	0.653GluCys: 0.653 ± 0.011	4.257GluAsp: 4.257 ± 0.038	4.992GluGlu: 4.992 ± 0.051	1.981GluPhe: 1.981 ± 0.017	3.597GluGly: 3.597 ± 0.029	1.38GluHis: 1.38 ± 0.015	2.846GluIle: 2.846 ± 0.022	3.375GluLys: 3.375 ± 0.03	5.182GluLeu: 5.182 ± 0.031	1.49GluMet: 1.49 ± 0.015	2.122GluAsn: 2.122 ± 0.02	2.966GluPro: 2.966 ± 0.041	2.357GluGln: 2.357 ± 0.024	3.632GluArg: 3.632 ± 0.029	4.244GluSer: 4.244 ± 0.036	3.716GluThr: 3.716 ± 0.038	3.606GluVal: 3.606 ± 0.024	0.928GluTrp: 0.928 ± 0.011	1.611GluTyr: 1.611 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.171PheAla: 3.171 ± 0.023	0.578PheCys: 0.578 ± 0.009	2.352PheAsp: 2.352 ± 0.02	2.141PheGlu: 2.141 ± 0.02	1.676PhePhe: 1.676 ± 0.019	2.92PheGly: 2.92 ± 0.026	0.9PheHis: 0.9 ± 0.012	1.8PheIle: 1.8 ± 0.018	1.51PheLys: 1.51 ± 0.016	3.475PheLeu: 3.475 ± 0.029	0.82PheMet: 0.82 ± 0.011	1.422PheAsn: 1.422 ± 0.016	1.989PhePro: 1.989 ± 0.018	1.455PheGln: 1.455 ± 0.015	1.978PheArg: 1.978 ± 0.019	2.997PheSer: 2.997 ± 0.025	2.146PheThr: 2.146 ± 0.021	2.5PheVal: 2.5 ± 0.022	0.674PheTrp: 0.674 ± 0.012	1.086PheTyr: 1.086 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.378GlyAla: 5.378 ± 0.038	0.947GlyCys: 0.947 ± 0.015	3.858GlyAsp: 3.858 ± 0.028	3.577GlyGlu: 3.577 ± 0.026	2.925GlyPhe: 2.925 ± 0.025	5.739GlyGly: 5.739 ± 0.048	1.735GlyHis: 1.735 ± 0.018	3.578GlyIle: 3.578 ± 0.029	3.352GlyLys: 3.352 ± 0.031	6.271GlyLeu: 6.271 ± 0.034	1.588GlyMet: 1.588 ± 0.018	2.525GlyAsn: 2.525 ± 0.024	3.415GlyPro: 3.415 ± 0.027	2.602GlyGln: 2.602 ± 0.032	4.145GlyArg: 4.145 ± 0.03	5.829GlySer: 5.829 ± 0.042	4.056GlyThr: 4.056 ± 0.033	4.43GlyVal: 4.43 ± 0.036	1.228GlyTrp: 1.228 ± 0.016	2.092GlyTyr: 2.092 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.881HisAla: 1.881 ± 0.018	0.338HisCys: 0.338 ± 0.008	1.396HisAsp: 1.396 ± 0.016	1.305HisGlu: 1.305 ± 0.014	0.912HisPhe: 0.912 ± 0.012	1.776HisGly: 1.776 ± 0.019	0.899HisHis: 0.899 ± 0.016	1.178HisIle: 1.178 ± 0.015	0.876HisLys: 0.876 ± 0.014	2.302HisLeu: 2.302 ± 0.022	0.491HisMet: 0.491 ± 0.009	0.816HisAsn: 0.816 ± 0.012	1.63HisPro: 1.63 ± 0.018	1.043HisGln: 1.043 ± 0.013	1.597HisArg: 1.597 ± 0.017	1.773HisSer: 1.773 ± 0.019	1.222HisThr: 1.222 ± 0.015	1.509HisVal: 1.509 ± 0.015	0.351HisTrp: 0.351 ± 0.007	0.666HisTyr: 0.666 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.156IleAla: 4.156 ± 0.031	0.741IleCys: 0.741 ± 0.017	2.833IleAsp: 2.833 ± 0.025	2.777IleGlu: 2.777 ± 0.02	1.904IlePhe: 1.904 ± 0.018	3.117IleGly: 3.117 ± 0.027	1.156IleHis: 1.156 ± 0.014	2.41IleIle: 2.41 ± 0.021	2.125IleLys: 2.125 ± 0.021	4.419IleLeu: 4.419 ± 0.033	1.018IleMet: 1.018 ± 0.014	1.725IleAsn: 1.725 ± 0.017	2.925IlePro: 2.925 ± 0.023	1.882IleGln: 1.882 ± 0.019	2.679IleArg: 2.679 ± 0.023	3.656IleSer: 3.656 ± 0.024	2.743IleThr: 2.743 ± 0.024	3.173IleVal: 3.173 ± 0.026	0.757IleTrp: 0.757 ± 0.012	1.307IleTyr: 1.307 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.361LysAla: 4.361 ± 0.032	0.493LysCys: 0.493 ± 0.009	2.805LysAsp: 2.805 ± 0.024	3.049LysGlu: 3.049 ± 0.028	1.457LysPhe: 1.457 ± 0.017	2.873LysGly: 2.873 ± 0.022	1.097LysHis: 1.097 ± 0.014	2.107LysIle: 2.107 ± 0.021	3.096LysLys: 3.096 ± 0.037	4.02LysLeu: 4.02 ± 0.029	1.016LysMet: 1.016 ± 0.014	1.646LysAsn: 1.646 ± 0.017	2.767LysPro: 2.767 ± 0.032	1.751LysGln: 1.751 ± 0.019	3.158LysArg: 3.158 ± 0.027	3.339LysSer: 3.339 ± 0.028	2.927LysThr: 2.927 ± 0.023	2.751LysVal: 2.751 ± 0.023	0.689LysTrp: 0.689 ± 0.01	1.274LysTyr: 1.274 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	8.194LeuAla: 8.194 ± 0.045	1.244LeuCys: 1.244 ± 0.018	5.441LeuAsp: 5.441 ± 0.032	5.519LeuGlu: 5.519 ± 0.036	3.35LeuPhe: 3.35 ± 0.028	6.221LeuGly: 6.221 ± 0.039	2.197LeuHis: 2.197 ± 0.02	3.809LeuIle: 3.809 ± 0.027	4.032LeuLys: 4.032 ± 0.029	8.238LeuLeu: 8.238 ± 0.053	1.807LeuMet: 1.807 ± 0.017	3.047LeuAsn: 3.047 ± 0.024	5.517LeuPro: 5.517 ± 0.048	3.768LeuGln: 3.768 ± 0.032	5.715LeuArg: 5.715 ± 0.034	7.167LeuSer: 7.167 ± 0.037	4.821LeuThr: 4.821 ± 0.03	5.716LeuVal: 5.716 ± 0.036	1.237LeuTrp: 1.237 ± 0.017	2.266LeuTyr: 2.266 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.424MetAla: 2.424 ± 0.021	0.248MetCys: 0.248 ± 0.007	1.32MetAsp: 1.32 ± 0.017	1.27MetGlu: 1.27 ± 0.013	0.78MetPhe: 0.78 ± 0.012	1.492MetGly: 1.492 ± 0.018	0.47MetHis: 0.47 ± 0.009	0.986MetIle: 0.986 ± 0.014	0.975MetLys: 0.975 ± 0.012	1.848MetLeu: 1.848 ± 0.018	0.588MetMet: 0.588 ± 0.011	0.76MetAsn: 0.76 ± 0.012	1.316MetPro: 1.316 ± 0.015	0.815MetGln: 0.815 ± 0.011	1.252MetArg: 1.252 ± 0.014	1.871MetSer: 1.871 ± 0.018	1.354MetThr: 1.354 ± 0.013	1.348MetVal: 1.348 ± 0.015	0.287MetTrp: 0.287 ± 0.008	0.512MetTyr: 0.512 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.991AsnAla: 2.991 ± 0.024	0.446AsnCys: 0.446 ± 0.01	1.938AsnAsp: 1.938 ± 0.02	1.926AsnGlu: 1.926 ± 0.017	1.334AsnPhe: 1.334 ± 0.017	2.86AsnGly: 2.86 ± 0.028	0.867AsnHis: 0.867 ± 0.012	1.856AsnIle: 1.856 ± 0.016	1.495AsnLys: 1.495 ± 0.013	3.172AsnLeu: 3.172 ± 0.024	0.854AsnMet: 0.854 ± 0.012	1.371AsnAsn: 1.371 ± 0.018	2.423AsnPro: 2.423 ± 0.027	1.3AsnGln: 1.3 ± 0.015	1.86AsnArg: 1.86 ± 0.017	2.612AsnSer: 2.612 ± 0.019	2.104AsnThr: 2.104 ± 0.018	2.219AsnVal: 2.219 ± 0.023	0.559AsnTrp: 0.559 ± 0.009	1.0AsnTyr: 1.0 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.454ProAla: 5.454 ± 0.046	0.565ProCys: 0.565 ± 0.01	3.419ProAsp: 3.419 ± 0.024	3.91ProGlu: 3.91 ± 0.034	2.087ProPhe: 2.087 ± 0.021	4.085ProGly: 4.085 ± 0.031	1.331ProHis: 1.331 ± 0.015	2.485ProIle: 2.485 ± 0.02	2.654ProLys: 2.654 ± 0.028	4.746ProLeu: 4.746 ± 0.029	1.094ProMet: 1.094 ± 0.013	2.11ProAsn: 2.11 ± 0.019	5.205ProPro: 5.205 ± 0.065	2.466ProGln: 2.466 ± 0.031	3.611ProArg: 3.611 ± 0.028	5.838ProSer: 5.838 ± 0.044	3.976ProThr: 3.976 ± 0.035	3.747ProVal: 3.747 ± 0.029	0.805ProTrp: 0.805 ± 0.012	1.415ProTyr: 1.415 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.525GlnAla: 3.525 ± 0.031	0.46GlnCys: 0.46 ± 0.009	2.211GlnAsp: 2.211 ± 0.017	2.252GlnGlu: 2.252 ± 0.023	1.296GlnPhe: 1.296 ± 0.018	2.504GlnGly: 2.504 ± 0.021	1.102GlnHis: 1.102 ± 0.015	1.744GlnIle: 1.744 ± 0.019	1.824GlnLys: 1.824 ± 0.017	3.472GlnLeu: 3.472 ± 0.025	0.898GlnMet: 0.898 ± 0.012	1.413GlnAsn: 1.413 ± 0.017	2.615GlnPro: 2.615 ± 0.028	2.461GlnGln: 2.461 ± 0.062	2.57GlnArg: 2.57 ± 0.02	3.009GlnSer: 3.009 ± 0.027	2.309GlnThr: 2.309 ± 0.023	2.29GlnVal: 2.29 ± 0.022	0.582GlnTrp: 0.582 ± 0.01	1.102GlnTyr: 1.102 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.725ArgAla: 4.725 ± 0.031	0.753ArgCys: 0.753 ± 0.011	3.549ArgAsp: 3.549 ± 0.029	3.674ArgGlu: 3.674 ± 0.036	2.167ArgPhe: 2.167 ± 0.019	3.775ArgGly: 3.775 ± 0.03	1.635ArgHis: 1.635 ± 0.016	2.785ArgIle: 2.785 ± 0.022	3.166ArgLys: 3.166 ± 0.025	5.539ArgLeu: 5.539 ± 0.037	1.291ArgMet: 1.291 ± 0.014	2.169ArgAsn: 2.169 ± 0.018	3.657ArgPro: 3.657 ± 0.029	2.536ArgGln: 2.536 ± 0.021	5.109ArgArg: 5.109 ± 0.036	4.572ArgSer: 4.572 ± 0.033	3.192ArgThr: 3.192 ± 0.023	3.418ArgVal: 3.418 ± 0.026	0.981ArgTrp: 0.981 ± 0.013	1.588ArgTyr: 1.588 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.59SerAla: 6.59 ± 0.045	0.926SerCys: 0.926 ± 0.022	4.41SerAsp: 4.41 ± 0.039	4.079SerGlu: 4.079 ± 0.032	3.056SerPhe: 3.056 ± 0.024	5.532SerGly: 5.532 ± 0.043	1.934SerHis: 1.934 ± 0.02	3.872SerIle: 3.872 ± 0.032	3.588SerLys: 3.588 ± 0.026	7.221SerLeu: 7.221 ± 0.037	1.722SerMet: 1.722 ± 0.019	2.859SerAsn: 2.859 ± 0.024	5.441SerPro: 5.441 ± 0.049	3.243SerGln: 3.243 ± 0.023	4.975SerArg: 4.975 ± 0.036	8.42SerSer: 8.42 ± 0.065	5.465SerThr: 5.465 ± 0.052	4.642SerVal: 4.642 ± 0.033	1.201SerTrp: 1.201 ± 0.016	2.006SerTyr: 2.006 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.465ThrAla: 5.465 ± 0.038	0.818ThrCys: 0.818 ± 0.041	2.96ThrAsp: 2.96 ± 0.028	3.267ThrGlu: 3.267 ± 0.034	2.212ThrPhe: 2.212 ± 0.021	4.206ThrGly: 4.206 ± 0.033	1.249ThrHis: 1.249 ± 0.015	3.034ThrIle: 3.034 ± 0.028	2.692ThrLys: 2.692 ± 0.024	5.162ThrLeu: 5.162 ± 0.03	1.229ThrMet: 1.229 ± 0.017	2.061ThrAsn: 2.061 ± 0.022	4.308ThrPro: 4.308 ± 0.034	2.072ThrGln: 2.072 ± 0.017	3.168ThrArg: 3.168 ± 0.022	5.273ThrSer: 5.273 ± 0.046	4.494ThrThr: 4.494 ± 0.077	3.783ThrVal: 3.783 ± 0.03	0.949ThrTrp: 0.949 ± 0.013	1.584ThrTyr: 1.584 ± 0.013	0.0ThrXaa: 0.0 ± 0.0
Val	5.7ValAla: 5.7 ± 0.034	0.92ValCys: 0.92 ± 0.036	3.957ValAsp: 3.957 ± 0.03	3.952ValGlu: 3.952 ± 0.032	2.562ValPhe: 2.562 ± 0.024	4.152ValGly: 4.152 ± 0.031	1.434ValHis: 1.434 ± 0.016	2.921ValIle: 2.921 ± 0.026	2.868ValLys: 2.868 ± 0.024	5.717ValLeu: 5.717 ± 0.039	1.341ValMet: 1.341 ± 0.013	2.2ValAsn: 2.2 ± 0.021	3.713ValPro: 3.713 ± 0.027	2.383ValGln: 2.383 ± 0.021	3.429ValArg: 3.429 ± 0.025	4.741ValSer: 4.741 ± 0.029	3.643ValThr: 3.643 ± 0.029	4.626ValVal: 4.626 ± 0.035	0.924ValTrp: 0.924 ± 0.012	1.747ValTyr: 1.747 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.248TrpAla: 1.248 ± 0.016	0.205TrpCys: 0.205 ± 0.006	0.963TrpAsp: 0.963 ± 0.013	0.865TrpGlu: 0.865 ± 0.011	0.584TrpPhe: 0.584 ± 0.007	1.017TrpGly: 1.017 ± 0.015	0.379TrpHis: 0.379 ± 0.008	0.794TrpIle: 0.794 ± 0.013	0.825TrpLys: 0.825 ± 0.011	1.428TrpLeu: 1.428 ± 0.014	0.388TrpMet: 0.388 ± 0.008	0.663TrpAsn: 0.663 ± 0.012	0.68TrpPro: 0.68 ± 0.011	0.613TrpGln: 0.613 ± 0.01	0.952TrpArg: 0.952 ± 0.013	1.095TrpSer: 1.095 ± 0.014	0.989TrpThr: 0.989 ± 0.014	0.947TrpVal: 0.947 ± 0.012	0.302TrpTrp: 0.302 ± 0.008	0.443TrpTyr: 0.443 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.105TyrAla: 2.105 ± 0.022	0.42TyrCys: 0.42 ± 0.008	1.643TyrAsp: 1.643 ± 0.019	1.487TyrGlu: 1.487 ± 0.015	1.17TyrPhe: 1.17 ± 0.014	2.074TyrGly: 2.074 ± 0.024	0.743TyrHis: 0.743 ± 0.011	1.258TyrIle: 1.258 ± 0.016	1.056TyrLys: 1.056 ± 0.014	2.569TyrLeu: 2.569 ± 0.021	0.608TyrMet: 0.608 ± 0.011	1.027TyrAsn: 1.027 ± 0.013	1.407TyrPro: 1.407 ± 0.014	1.049TyrGln: 1.049 ± 0.015	1.563TyrArg: 1.563 ± 0.016	1.961TyrSer: 1.961 ± 0.018	1.543TyrThr: 1.543 ± 0.018	1.629TyrVal: 1.629 ± 0.018	0.467TyrTrp: 0.467 ± 0.008	0.905TyrTyr: 0.905 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12683 proteins (6561620 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---