Amino acid dipepetide frequency for Elderberry latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.108AlaAla: 10.108 ± 2.616
2.022AlaCys: 2.022 ± 0.787
3.369AlaAsp: 3.369 ± 2.928
3.369AlaGlu: 3.369 ± 1.365
3.369AlaPhe: 3.369 ± 0.594
4.717AlaGly: 4.717 ± 3.685
2.022AlaHis: 2.022 ± 1.747
4.043AlaIle: 4.043 ± 1.016
2.695AlaLys: 2.695 ± 0.459
8.76AlaLeu: 8.76 ± 2.093
0.0AlaMet: 0.0 ± 0.0
5.391AlaAsn: 5.391 ± 2.004
2.695AlaPro: 2.695 ± 0.871
4.043AlaGln: 4.043 ± 1.141
2.695AlaArg: 2.695 ± 1.58
3.369AlaSer: 3.369 ± 2.109
1.348AlaThr: 1.348 ± 0.632
4.717AlaVal: 4.717 ± 2.223
1.348AlaTrp: 1.348 ± 0.839
6.065AlaTyr: 6.065 ± 1.698
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.348CysAsp: 1.348 ± 0.632
0.674CysGlu: 0.674 ± 0.42
0.0CysPhe: 0.0 ± 0.0
2.695CysGly: 2.695 ± 0.459
0.674CysHis: 0.674 ± 0.42
2.022CysIle: 2.022 ± 0.787
1.348CysLys: 1.348 ± 0.632
2.022CysLeu: 2.022 ± 1.102
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.674CysPro: 0.674 ± 0.42
2.022CysGln: 2.022 ± 0.787
0.0CysArg: 0.0 ± 0.0
1.348CysSer: 1.348 ± 0.435
0.0CysThr: 0.0 ± 0.0
2.022CysVal: 2.022 ± 0.787
0.674CysTrp: 0.674 ± 0.42
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.412AspAla: 7.412 ± 1.475
2.022AspCys: 2.022 ± 1.259
0.674AspAsp: 0.674 ± 0.42
1.348AspGlu: 1.348 ± 0.839
0.674AspPhe: 0.674 ± 0.42
2.022AspGly: 2.022 ± 1.045
2.022AspHis: 2.022 ± 0.787
2.022AspIle: 2.022 ± 1.133
4.717AspLys: 4.717 ± 1.239
2.695AspLeu: 2.695 ± 0.871
0.674AspMet: 0.674 ± 0.42
2.022AspAsn: 2.022 ± 1.045
3.369AspPro: 3.369 ± 0.831
4.043AspGln: 4.043 ± 1.937
1.348AspArg: 1.348 ± 0.632
4.717AspSer: 4.717 ± 1.776
2.695AspThr: 2.695 ± 2.05
5.391AspVal: 5.391 ± 1.035
0.0AspTrp: 0.0 ± 0.0
3.369AspTyr: 3.369 ± 1.365
0.0AspXaa: 0.0 ± 0.0
Glu
3.369GluAla: 3.369 ± 1.094
0.674GluCys: 0.674 ± 0.666
2.695GluAsp: 2.695 ± 1.264
0.674GluGlu: 0.674 ± 0.42
2.695GluPhe: 2.695 ± 0.859
4.717GluGly: 4.717 ± 1.368
3.369GluHis: 3.369 ± 1.041
2.022GluIle: 2.022 ± 0.787
2.695GluLys: 2.695 ± 0.859
9.434GluLeu: 9.434 ± 2.598
1.348GluMet: 1.348 ± 0.839
1.348GluAsn: 1.348 ± 0.839
3.369GluPro: 3.369 ± 1.455
0.674GluGln: 0.674 ± 0.666
2.695GluArg: 2.695 ± 1.384
0.674GluSer: 0.674 ± 0.42
2.695GluThr: 2.695 ± 1.264
4.043GluVal: 4.043 ± 1.298
2.022GluTrp: 2.022 ± 0.787
2.022GluTyr: 2.022 ± 1.259
0.0GluXaa: 0.0 ± 0.0
Phe
4.717PheAla: 4.717 ± 1.375
0.674PheCys: 0.674 ± 0.42
3.369PheAsp: 3.369 ± 1.041
1.348PheGlu: 1.348 ± 0.839
0.674PhePhe: 0.674 ± 1.152
4.717PheGly: 4.717 ± 1.976
1.348PheHis: 1.348 ± 1.003
2.695PheIle: 2.695 ± 1.264
2.695PheLys: 2.695 ± 1.153
4.043PheLeu: 4.043 ± 2.411
2.022PheMet: 2.022 ± 0.874
0.674PheAsn: 0.674 ± 0.666
2.022PhePro: 2.022 ± 0.649
0.674PheGln: 0.674 ± 0.666
2.695PheArg: 2.695 ± 0.859
3.369PheSer: 3.369 ± 0.594
4.043PheThr: 4.043 ± 0.746
2.022PheVal: 2.022 ± 1.133
0.674PheTrp: 0.674 ± 0.42
0.674PheTyr: 0.674 ± 0.42
0.0PheXaa: 0.0 ± 0.0
Gly
4.717GlyAla: 4.717 ± 1.663
0.674GlyCys: 0.674 ± 0.42
3.369GlyAsp: 3.369 ± 1.241
5.391GlyGlu: 5.391 ± 1.742
6.065GlyPhe: 6.065 ± 1.698
4.043GlyGly: 4.043 ± 0.633
0.674GlyHis: 0.674 ± 0.42
2.022GlyIle: 2.022 ± 1.057
4.717GlyLys: 4.717 ± 1.745
8.086GlyLeu: 8.086 ± 1.872
3.369GlyMet: 3.369 ± 1.455
3.369GlyAsn: 3.369 ± 2.56
2.022GlyPro: 2.022 ± 0.649
2.022GlyGln: 2.022 ± 1.163
4.043GlyArg: 4.043 ± 1.306
1.348GlySer: 1.348 ± 1.333
5.391GlyThr: 5.391 ± 0.76
4.717GlyVal: 4.717 ± 1.301
0.674GlyTrp: 0.674 ± 0.666
1.348GlyTyr: 1.348 ± 0.839
0.0GlyXaa: 0.0 ± 0.0
His
0.674HisAla: 0.674 ± 0.666
0.0HisCys: 0.0 ± 0.0
0.674HisAsp: 0.674 ± 0.666
0.674HisGlu: 0.674 ± 0.42
2.695HisPhe: 2.695 ± 0.994
0.674HisGly: 0.674 ± 0.42
0.0HisHis: 0.0 ± 0.0
1.348HisIle: 1.348 ± 1.419
4.043HisLys: 4.043 ± 0.92
0.674HisLeu: 0.674 ± 0.42
0.0HisMet: 0.0 ± 0.0
1.348HisAsn: 1.348 ± 0.839
0.0HisPro: 0.0 ± 0.0
0.674HisGln: 0.674 ± 0.42
2.022HisArg: 2.022 ± 0.536
3.369HisSer: 3.369 ± 2.099
1.348HisThr: 1.348 ± 0.632
1.348HisVal: 1.348 ± 1.003
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.695IleAla: 2.695 ± 1.153
0.0IleCys: 0.0 ± 0.0
1.348IleAsp: 1.348 ± 1.003
2.695IleGlu: 2.695 ± 0.982
0.0IlePhe: 0.0 ± 0.0
2.695IleGly: 2.695 ± 0.459
0.674IleHis: 0.674 ± 0.42
1.348IleIle: 1.348 ± 1.333
2.695IleLys: 2.695 ± 0.994
4.717IleLeu: 4.717 ± 1.593
0.674IleMet: 0.674 ± 0.392
2.695IleAsn: 2.695 ± 1.092
2.695IlePro: 2.695 ± 0.459
0.674IleGln: 0.674 ± 0.42
2.695IleArg: 2.695 ± 0.859
5.391IleSer: 5.391 ± 2.561
3.369IleThr: 3.369 ± 1.094
2.695IleVal: 2.695 ± 1.02
1.348IleTrp: 1.348 ± 0.632
3.369IleTyr: 3.369 ± 0.594
0.0IleXaa: 0.0 ± 0.0
Lys
2.695LysAla: 2.695 ± 1.455
2.022LysCys: 2.022 ± 0.787
2.695LysAsp: 2.695 ± 1.384
3.369LysGlu: 3.369 ± 1.094
4.717LysPhe: 4.717 ± 1.043
2.695LysGly: 2.695 ± 0.982
0.674LysHis: 0.674 ± 0.42
4.717LysIle: 4.717 ± 2.433
3.369LysLys: 3.369 ± 1.702
4.043LysLeu: 4.043 ± 1.141
2.022LysMet: 2.022 ± 0.823
3.369LysAsn: 3.369 ± 1.094
3.369LysPro: 3.369 ± 1.702
1.348LysGln: 1.348 ± 0.632
2.022LysArg: 2.022 ± 0.787
5.391LysSer: 5.391 ± 3.374
2.695LysThr: 2.695 ± 1.092
5.391LysVal: 5.391 ± 1.778
0.674LysTrp: 0.674 ± 0.42
3.369LysTyr: 3.369 ± 0.907
0.674LysXaa: 0.674 ± 0.42
Leu
10.782LeuAla: 10.782 ± 2.878
2.022LeuCys: 2.022 ± 1.163
2.022LeuAsp: 2.022 ± 1.057
6.739LeuGlu: 6.739 ± 1.188
2.695LeuPhe: 2.695 ± 1.02
7.412LeuGly: 7.412 ± 0.872
2.022LeuHis: 2.022 ± 0.649
4.043LeuIle: 4.043 ± 0.746
4.043LeuLys: 4.043 ± 1.842
9.434LeuLeu: 9.434 ± 3.695
3.369LeuMet: 3.369 ± 0.594
2.695LeuAsn: 2.695 ± 1.019
2.695LeuPro: 2.695 ± 0.994
1.348LeuGln: 1.348 ± 0.632
4.717LeuArg: 4.717 ± 0.929
9.434LeuSer: 9.434 ± 0.846
8.76LeuThr: 8.76 ± 2.311
4.043LeuVal: 4.043 ± 1.941
1.348LeuTrp: 1.348 ± 0.435
1.348LeuTyr: 1.348 ± 1.333
0.0LeuXaa: 0.0 ± 0.0
Met
2.695MetAla: 2.695 ± 1.2
0.0MetCys: 0.0 ± 0.0
2.022MetAsp: 2.022 ± 1.057
2.022MetGlu: 2.022 ± 1.259
1.348MetPhe: 1.348 ± 0.839
3.369MetGly: 3.369 ± 1.365
1.348MetHis: 1.348 ± 0.839
0.0MetIle: 0.0 ± 0.0
2.695MetLys: 2.695 ± 1.092
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.611
0.0MetAsn: 0.0 ± 0.0
1.348MetPro: 1.348 ± 0.632
0.0MetGln: 0.0 ± 0.0
0.674MetArg: 0.674 ± 0.42
2.695MetSer: 2.695 ± 0.859
1.348MetThr: 1.348 ± 1.333
0.674MetVal: 0.674 ± 0.42
1.348MetTrp: 1.348 ± 0.632
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.348AsnAla: 1.348 ± 1.333
0.0AsnCys: 0.0 ± 0.0
3.369AsnAsp: 3.369 ± 1.365
1.348AsnGlu: 1.348 ± 0.632
1.348AsnPhe: 1.348 ± 1.003
3.369AsnGly: 3.369 ± 1.585
1.348AsnHis: 1.348 ± 0.632
2.022AsnIle: 2.022 ± 1.045
1.348AsnLys: 1.348 ± 1.333
2.695AsnLeu: 2.695 ± 1.02
0.0AsnMet: 0.0 ± 0.0
1.348AsnAsn: 1.348 ± 0.435
3.369AsnPro: 3.369 ± 0.594
2.695AsnGln: 2.695 ± 0.459
1.348AsnArg: 1.348 ± 0.632
5.391AsnSer: 5.391 ± 1.18
2.695AsnThr: 2.695 ± 0.871
2.022AsnVal: 2.022 ± 0.536
0.0AsnTrp: 0.0 ± 0.0
1.348AsnTyr: 1.348 ± 1.419
0.0AsnXaa: 0.0 ± 0.0
Pro
2.022ProAla: 2.022 ± 0.536
0.0ProCys: 0.0 ± 0.0
4.043ProAsp: 4.043 ± 1.575
5.391ProGlu: 5.391 ± 2.529
2.022ProPhe: 2.022 ± 0.787
4.043ProGly: 4.043 ± 1.169
0.674ProHis: 0.674 ± 0.666
1.348ProIle: 1.348 ± 0.839
2.695ProLys: 2.695 ± 1.019
1.348ProLeu: 1.348 ± 0.435
1.348ProMet: 1.348 ± 0.632
2.022ProAsn: 2.022 ± 1.163
0.0ProPro: 0.0 ± 0.0
1.348ProGln: 1.348 ± 0.435
8.086ProArg: 8.086 ± 1.739
1.348ProSer: 1.348 ± 2.303
3.369ProThr: 3.369 ± 0.831
5.391ProVal: 5.391 ± 0.938
0.0ProTrp: 0.0 ± 0.0
0.674ProTyr: 0.674 ± 0.42
0.0ProXaa: 0.0 ± 0.0
Gln
2.695GlnAla: 2.695 ± 0.459
2.022GlnCys: 2.022 ± 0.787
2.695GlnAsp: 2.695 ± 1.089
1.348GlnGlu: 1.348 ± 0.839
0.0GlnPhe: 0.0 ± 0.0
2.022GlnGly: 2.022 ± 1.034
0.674GlnHis: 0.674 ± 0.42
0.674GlnIle: 0.674 ± 0.42
2.022GlnLys: 2.022 ± 1.045
1.348GlnLeu: 1.348 ± 0.839
2.022GlnMet: 2.022 ± 1.102
0.0GlnAsn: 0.0 ± 0.0
2.022GlnPro: 2.022 ± 0.536
0.674GlnGln: 0.674 ± 0.42
1.348GlnArg: 1.348 ± 1.333
2.022GlnSer: 2.022 ± 1.045
1.348GlnThr: 1.348 ± 0.632
4.043GlnVal: 4.043 ± 1.246
0.0GlnTrp: 0.0 ± 0.0
1.348GlnTyr: 1.348 ± 0.435
0.0GlnXaa: 0.0 ± 0.0
Arg
4.717ArgAla: 4.717 ± 1.663
1.348ArgCys: 1.348 ± 0.632
3.369ArgAsp: 3.369 ± 0.882
4.717ArgGlu: 4.717 ± 1.045
1.348ArgPhe: 1.348 ± 0.435
5.391ArgGly: 5.391 ± 2.06
0.674ArgHis: 0.674 ± 0.42
0.674ArgIle: 0.674 ± 0.42
2.695ArgLys: 2.695 ± 1.019
5.391ArgLeu: 5.391 ± 0.938
2.695ArgMet: 2.695 ± 0.859
4.717ArgAsn: 4.717 ± 1.301
3.369ArgPro: 3.369 ± 1.351
0.0ArgGln: 0.0 ± 0.0
6.739ArgArg: 6.739 ± 1.861
4.717ArgSer: 4.717 ± 1.283
4.717ArgThr: 4.717 ± 1.157
5.391ArgVal: 5.391 ± 2.184
1.348ArgTrp: 1.348 ± 0.839
2.695ArgTyr: 2.695 ± 0.859
0.0ArgXaa: 0.0 ± 0.0
Ser
4.717SerAla: 4.717 ± 4.341
2.022SerCys: 2.022 ± 0.787
4.717SerAsp: 4.717 ± 1.614
3.369SerGlu: 3.369 ± 0.831
2.695SerPhe: 2.695 ± 1.02
3.369SerGly: 3.369 ± 1.079
1.348SerHis: 1.348 ± 1.046
4.043SerIle: 4.043 ± 2.022
4.043SerLys: 4.043 ± 1.729
6.065SerLeu: 6.065 ± 1.399
0.674SerMet: 0.674 ± 0.666
0.674SerAsn: 0.674 ± 0.666
5.391SerPro: 5.391 ± 1.283
3.369SerGln: 3.369 ± 0.831
9.434SerArg: 9.434 ± 1.646
4.043SerSer: 4.043 ± 3.021
2.022SerThr: 2.022 ± 1.163
4.717SerVal: 4.717 ± 1.969
0.0SerTrp: 0.0 ± 0.0
3.369SerTyr: 3.369 ± 1.325
0.0SerXaa: 0.0 ± 0.0
Thr
1.348ThrAla: 1.348 ± 0.632
0.674ThrCys: 0.674 ± 0.42
0.674ThrAsp: 0.674 ± 0.666
2.022ThrGlu: 2.022 ± 0.649
8.76ThrPhe: 8.76 ± 1.963
0.674ThrGly: 0.674 ± 1.039
2.022ThrHis: 2.022 ± 1.133
3.369ThrIle: 3.369 ± 0.831
4.043ThrLys: 4.043 ± 0.92
4.717ThrLeu: 4.717 ± 2.456
0.674ThrMet: 0.674 ± 0.666
2.022ThrAsn: 2.022 ± 0.649
5.391ThrPro: 5.391 ± 0.933
2.695ThrGln: 2.695 ± 0.459
7.412ThrArg: 7.412 ± 1.641
5.391ThrSer: 5.391 ± 1.566
4.717ThrThr: 4.717 ± 0.874
6.739ThrVal: 6.739 ± 1.186
0.0ThrTrp: 0.0 ± 0.0
0.674ThrTyr: 0.674 ± 0.666
0.0ThrXaa: 0.0 ± 0.0
Val
6.739ValAla: 6.739 ± 2.049
1.348ValCys: 1.348 ± 0.632
9.434ValAsp: 9.434 ± 1.548
5.391ValGlu: 5.391 ± 1.7
1.348ValPhe: 1.348 ± 1.273
6.739ValGly: 6.739 ± 0.664
0.0ValHis: 0.0 ± 0.0
2.022ValIle: 2.022 ± 0.536
4.717ValLys: 4.717 ± 1.043
10.108ValLeu: 10.108 ± 2.911
2.022ValMet: 2.022 ± 0.787
2.695ValAsn: 2.695 ± 0.459
2.695ValPro: 2.695 ± 0.871
1.348ValGln: 1.348 ± 0.435
4.043ValArg: 4.043 ± 1.072
1.348ValSer: 1.348 ± 1.046
7.412ValThr: 7.412 ± 2.679
6.739ValVal: 6.739 ± 1.661
0.0ValTrp: 0.0 ± 0.0
2.695ValTyr: 2.695 ± 1.02
0.0ValXaa: 0.0 ± 0.0
Trp
1.348TrpAla: 1.348 ± 0.435
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.348TrpGlu: 1.348 ± 0.839
1.348TrpPhe: 1.348 ± 0.632
2.022TrpGly: 2.022 ± 1.259
0.0TrpHis: 0.0 ± 0.0
0.674TrpIle: 0.674 ± 0.42
1.348TrpLys: 1.348 ± 0.632
2.022TrpLeu: 2.022 ± 0.787
0.674TrpMet: 0.674 ± 0.42
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.674TrpArg: 0.674 ± 0.666
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.674TrpVal: 0.674 ± 0.42
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.348TyrAla: 1.348 ± 0.435
0.0TyrCys: 0.0 ± 0.0
1.348TyrAsp: 1.348 ± 0.632
0.0TyrGlu: 0.0 ± 0.0
1.348TyrPhe: 1.348 ± 0.435
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
3.369TyrIle: 3.369 ± 0.907
2.695TyrLys: 2.695 ± 0.871
3.369TyrLeu: 3.369 ± 1.455
0.0TyrMet: 0.0 ± 0.0
2.022TyrAsn: 2.022 ± 0.536
0.674TyrPro: 0.674 ± 0.42
0.674TyrGln: 0.674 ± 0.42
2.022TyrArg: 2.022 ± 1.259
4.717TyrSer: 4.717 ± 2.147
4.043TyrThr: 4.043 ± 1.016
6.065TyrVal: 6.065 ± 1.606
0.674TyrTrp: 0.674 ± 0.42
2.022TyrTyr: 2.022 ± 1.163
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.674XaaGly: 0.674 ± 0.42
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1485 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski