Amino acid dipepetide frequency for Dethiosulfovibrio peptidovorans DSM 11002

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.22AlaAla: 7.22 ± 0.124	0.982AlaCys: 0.982 ± 0.044	4.014AlaAsp: 4.014 ± 0.08	5.141AlaGlu: 5.141 ± 0.085	3.423AlaPhe: 3.423 ± 0.073	6.632AlaGly: 6.632 ± 0.119	1.141AlaHis: 1.141 ± 0.04	5.271AlaIle: 5.271 ± 0.086	3.803AlaLys: 3.803 ± 0.078	9.74AlaLeu: 9.74 ± 0.129	3.124AlaMet: 3.124 ± 0.062	1.858AlaAsn: 1.858 ± 0.05	2.847AlaPro: 2.847 ± 0.063	2.022AlaGln: 2.022 ± 0.055	4.725AlaArg: 4.725 ± 0.075	5.618AlaSer: 5.618 ± 0.098	3.505AlaThr: 3.505 ± 0.075	7.563AlaVal: 7.563 ± 0.114	0.898AlaTrp: 0.898 ± 0.035	1.985AlaTyr: 1.985 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.829CysAla: 0.829 ± 0.034	0.232CysCys: 0.232 ± 0.018	0.829CysAsp: 0.829 ± 0.037	0.568CysGlu: 0.568 ± 0.025	0.492CysPhe: 0.492 ± 0.025	1.258CysGly: 1.258 ± 0.045	0.276CysHis: 0.276 ± 0.019	0.559CysIle: 0.559 ± 0.029	0.373CysLys: 0.373 ± 0.02	1.206CysLeu: 1.206 ± 0.041	0.321CysMet: 0.321 ± 0.021	0.299CysAsn: 0.299 ± 0.021	0.811CysPro: 0.811 ± 0.034	0.245CysGln: 0.245 ± 0.02	0.974CysArg: 0.974 ± 0.034	1.014CysSer: 1.014 ± 0.035	0.513CysThr: 0.513 ± 0.028	0.748CysVal: 0.748 ± 0.032	0.175CysTrp: 0.175 ± 0.015	0.338CysTyr: 0.338 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	3.551AspAla: 3.551 ± 0.071	0.649AspCys: 0.649 ± 0.028	3.654AspAsp: 3.654 ± 0.087	4.593AspGlu: 4.593 ± 0.091	2.413AspPhe: 2.413 ± 0.056	6.041AspGly: 6.041 ± 0.098	1.091AspHis: 1.091 ± 0.04	3.603AspIle: 3.603 ± 0.073	2.54AspLys: 2.54 ± 0.057	7.215AspLeu: 7.215 ± 0.095	2.097AspMet: 2.097 ± 0.051	1.287AspAsn: 1.287 ± 0.046	3.152AspPro: 3.152 ± 0.066	1.41AspGln: 1.41 ± 0.046	5.089AspArg: 5.089 ± 0.093	3.58AspSer: 3.58 ± 0.078	2.135AspThr: 2.135 ± 0.064	5.151AspVal: 5.151 ± 0.083	0.807AspTrp: 0.807 ± 0.038	1.559AspTyr: 1.559 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	6.282GluAla: 6.282 ± 0.105	0.526GluCys: 0.526 ± 0.023	4.551GluAsp: 4.551 ± 0.073	6.249GluGlu: 6.249 ± 0.103	1.823GluPhe: 1.823 ± 0.049	5.75GluGly: 5.75 ± 0.089	0.958GluHis: 0.958 ± 0.035	4.817GluIle: 4.817 ± 0.079	4.613GluLys: 4.613 ± 0.097	6.437GluLeu: 6.437 ± 0.106	2.23GluMet: 2.23 ± 0.063	2.323GluAsn: 2.323 ± 0.054	2.247GluPro: 2.247 ± 0.048	1.405GluGln: 1.405 ± 0.042	5.146GluArg: 5.146 ± 0.11	3.996GluSer: 3.996 ± 0.073	3.333GluThr: 3.333 ± 0.069	4.946GluVal: 4.946 ± 0.092	0.69GluTrp: 0.69 ± 0.033	1.384GluTyr: 1.384 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	2.679PheAla: 2.679 ± 0.066	0.566PheCys: 0.566 ± 0.023	2.525PheAsp: 2.525 ± 0.063	2.02PheGlu: 2.02 ± 0.051	1.89PhePhe: 1.89 ± 0.052	3.253PheGly: 3.253 ± 0.057	0.695PheHis: 0.695 ± 0.034	1.918PheIle: 1.918 ± 0.056	1.498PheLys: 1.498 ± 0.046	4.079PheLeu: 4.079 ± 0.09	1.119PheMet: 1.119 ± 0.043	0.913PheAsn: 0.913 ± 0.035	1.94PhePro: 1.94 ± 0.05	0.98PheGln: 0.98 ± 0.034	2.335PheArg: 2.335 ± 0.056	3.31PheSer: 3.31 ± 0.068	1.498PheThr: 1.498 ± 0.05	3.18PheVal: 3.18 ± 0.068	0.47PheTrp: 0.47 ± 0.025	0.986PheTyr: 0.986 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	7.047GlyAla: 7.047 ± 0.111	1.211GlyCys: 1.211 ± 0.041	5.218GlyAsp: 5.218 ± 0.088	5.529GlyGlu: 5.529 ± 0.097	3.464GlyPhe: 3.464 ± 0.07	7.233GlyGly: 7.233 ± 0.142	1.572GlyHis: 1.572 ± 0.051	5.563GlyIle: 5.563 ± 0.092	4.982GlyLys: 4.982 ± 0.078	8.66GlyLeu: 8.66 ± 0.118	2.76GlyMet: 2.76 ± 0.063	2.489GlyAsn: 2.489 ± 0.069	2.849GlyPro: 2.849 ± 0.061	2.026GlyGln: 2.026 ± 0.048	5.598GlyArg: 5.598 ± 0.085	5.571GlySer: 5.571 ± 0.097	4.58GlyThr: 4.58 ± 0.088	6.736GlyVal: 6.736 ± 0.091	1.257GlyTrp: 1.257 ± 0.042	2.757GlyTyr: 2.757 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	0.893HisAla: 0.893 ± 0.034	0.282HisCys: 0.282 ± 0.02	0.95HisAsp: 0.95 ± 0.038	0.773HisGlu: 0.773 ± 0.033	0.642HisPhe: 0.642 ± 0.029	1.507HisGly: 1.507 ± 0.039	0.397HisHis: 0.397 ± 0.027	0.985HisIle: 0.985 ± 0.034	0.568HisLys: 0.568 ± 0.025	1.655HisLeu: 1.655 ± 0.049	0.473HisMet: 0.473 ± 0.026	0.433HisAsn: 0.433 ± 0.024	1.047HisPro: 1.047 ± 0.037	0.406HisGln: 0.406 ± 0.023	1.291HisArg: 1.291 ± 0.044	1.026HisSer: 1.026 ± 0.041	0.632HisThr: 0.632 ± 0.029	1.206HisVal: 1.206 ± 0.046	0.208HisTrp: 0.208 ± 0.017	0.462HisTyr: 0.462 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.231IleAla: 5.231 ± 0.099	0.856IleCys: 0.856 ± 0.037	3.602IleAsp: 3.602 ± 0.079	3.681IleGlu: 3.681 ± 0.078	2.084IlePhe: 2.084 ± 0.054	5.079IleGly: 5.079 ± 0.089	0.954IleHis: 0.954 ± 0.034	2.482IleIle: 2.482 ± 0.066	2.686IleLys: 2.686 ± 0.067	5.955IleLeu: 5.955 ± 0.09	1.591IleMet: 1.591 ± 0.046	1.473IleAsn: 1.473 ± 0.048	3.349IlePro: 3.349 ± 0.064	1.37IleGln: 1.37 ± 0.04	3.558IleArg: 3.558 ± 0.077	4.806IleSer: 4.806 ± 0.075	2.66IleThr: 2.66 ± 0.061	4.626IleVal: 4.626 ± 0.078	0.69IleTrp: 0.69 ± 0.033	1.511IleTyr: 1.511 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	4.848LysAla: 4.848 ± 0.088	0.387LysCys: 0.387 ± 0.026	3.312LysAsp: 3.312 ± 0.067	3.927LysGlu: 3.927 ± 0.082	1.148LysPhe: 1.148 ± 0.043	4.83LysGly: 4.83 ± 0.081	0.548LysHis: 0.548 ± 0.028	2.923LysIle: 2.923 ± 0.057	3.473LysLys: 3.473 ± 0.081	4.181LysLeu: 4.181 ± 0.072	1.317LysMet: 1.317 ± 0.046	1.71LysAsn: 1.71 ± 0.051	1.739LysPro: 1.739 ± 0.051	0.845LysGln: 0.845 ± 0.036	3.106LysArg: 3.106 ± 0.072	2.829LysSer: 2.829 ± 0.062	2.649LysThr: 2.649 ± 0.053	3.978LysVal: 3.978 ± 0.079	0.456LysTrp: 0.456 ± 0.03	1.038LysTyr: 1.038 ± 0.038	0.0LysXaa: 0.0 ± 0.0
Leu	9.221LeuAla: 9.221 ± 0.124	1.391LeuCys: 1.391 ± 0.044	6.276LeuAsp: 6.276 ± 0.099	7.125LeuGlu: 7.125 ± 0.108	4.074LeuPhe: 4.074 ± 0.08	8.34LeuGly: 8.34 ± 0.112	1.489LeuHis: 1.489 ± 0.046	5.129LeuIle: 5.129 ± 0.086	5.362LeuLys: 5.362 ± 0.098	9.298LeuLeu: 9.298 ± 0.158	2.866LeuMet: 2.866 ± 0.065	2.731LeuAsn: 2.731 ± 0.059	4.978LeuPro: 4.978 ± 0.09	2.132LeuGln: 2.132 ± 0.048	6.257LeuArg: 6.257 ± 0.102	9.17LeuSer: 9.17 ± 0.128	4.525LeuThr: 4.525 ± 0.081	7.331LeuVal: 7.331 ± 0.102	1.455LeuTrp: 1.455 ± 0.049	2.54LeuTyr: 2.54 ± 0.063	0.0LeuXaa: 0.0 ± 0.0
Met	3.568MetAla: 3.568 ± 0.074	0.232MetCys: 0.232 ± 0.018	2.278MetAsp: 2.278 ± 0.055	2.676MetGlu: 2.676 ± 0.061	0.771MetPhe: 0.771 ± 0.029	2.866MetGly: 2.866 ± 0.062	0.289MetHis: 0.289 ± 0.021	1.717MetIle: 1.717 ± 0.048	1.751MetLys: 1.751 ± 0.05	2.313MetLeu: 2.313 ± 0.057	0.783MetMet: 0.783 ± 0.031	0.971MetAsn: 0.971 ± 0.039	1.232MetPro: 1.232 ± 0.043	0.46MetGln: 0.46 ± 0.025	1.513MetArg: 1.513 ± 0.043	2.096MetSer: 2.096 ± 0.05	1.879MetThr: 1.879 ± 0.048	2.792MetVal: 2.792 ± 0.063	0.246MetTrp: 0.246 ± 0.017	0.542MetTyr: 0.542 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	1.874AsnAla: 1.874 ± 0.051	0.416AsnCys: 0.416 ± 0.026	1.52AsnAsp: 1.52 ± 0.047	1.54AsnGlu: 1.54 ± 0.047	0.96AsnPhe: 0.96 ± 0.037	2.447AsnGly: 2.447 ± 0.066	0.444AsnHis: 0.444 ± 0.024	1.444AsnIle: 1.444 ± 0.047	1.047AsnLys: 1.047 ± 0.034	2.9AsnLeu: 2.9 ± 0.068	0.815AsnMet: 0.815 ± 0.033	0.639AsnAsn: 0.639 ± 0.036	1.711AsnPro: 1.711 ± 0.049	0.6AsnGln: 0.6 ± 0.027	2.027AsnArg: 2.027 ± 0.059	1.594AsnSer: 1.594 ± 0.047	1.033AsnThr: 1.033 ± 0.038	2.327AsnVal: 2.327 ± 0.065	0.393AsnTrp: 0.393 ± 0.024	0.812AsnTyr: 0.812 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	2.854ProAla: 2.854 ± 0.072	0.497ProCys: 0.497 ± 0.026	3.01ProAsp: 3.01 ± 0.07	3.897ProGlu: 3.897 ± 0.082	2.027ProPhe: 2.027 ± 0.054	3.877ProGly: 3.877 ± 0.085	0.77ProHis: 0.77 ± 0.031	2.485ProIle: 2.485 ± 0.054	1.953ProLys: 1.953 ± 0.046	4.465ProLeu: 4.465 ± 0.08	1.324ProMet: 1.324 ± 0.037	0.997ProAsn: 0.997 ± 0.038	1.599ProPro: 1.599 ± 0.055	1.004ProGln: 1.004 ± 0.034	2.096ProArg: 2.096 ± 0.05	3.282ProSer: 3.282 ± 0.062	1.823ProThr: 1.823 ± 0.051	4.035ProVal: 4.035 ± 0.08	0.685ProTrp: 0.685 ± 0.03	1.308ProTyr: 1.308 ± 0.047	0.0ProXaa: 0.0 ± 0.0
Gln	2.212GlnAla: 2.212 ± 0.057	0.185GlnCys: 0.185 ± 0.016	1.299GlnAsp: 1.299 ± 0.038	1.831GlnGlu: 1.831 ± 0.053	0.696GlnPhe: 0.696 ± 0.029	1.941GlnGly: 1.941 ± 0.05	0.315GlnHis: 0.315 ± 0.017	1.452GlnIle: 1.452 ± 0.037	1.155GlnLys: 1.155 ± 0.038	1.895GlnLeu: 1.895 ± 0.052	0.659GlnMet: 0.659 ± 0.027	0.731GlnAsn: 0.731 ± 0.037	0.739GlnPro: 0.739 ± 0.031	0.57GlnGln: 0.57 ± 0.034	1.503GlnArg: 1.503 ± 0.05	1.299GlnSer: 1.299 ± 0.043	1.106GlnThr: 1.106 ± 0.04	1.831GlnVal: 1.831 ± 0.055	0.262GlnTrp: 0.262 ± 0.021	0.521GlnTyr: 0.521 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	4.383ArgAla: 4.383 ± 0.069	0.889ArgCys: 0.889 ± 0.039	3.773ArgAsp: 3.773 ± 0.07	4.863ArgGlu: 4.863 ± 0.091	2.608ArgPhe: 2.608 ± 0.062	4.899ArgGly: 4.899 ± 0.091	1.193ArgHis: 1.193 ± 0.037	4.336ArgIle: 4.336 ± 0.075	3.616ArgLys: 3.616 ± 0.077	6.521ArgLeu: 6.521 ± 0.095	2.165ArgMet: 2.165 ± 0.054	1.81ArgAsn: 1.81 ± 0.046	2.505ArgPro: 2.505 ± 0.061	1.607ArgGln: 1.607 ± 0.043	4.695ArgArg: 4.695 ± 0.085	4.769ArgSer: 4.769 ± 0.099	2.639ArgThr: 2.639 ± 0.049	3.857ArgVal: 3.857 ± 0.071	1.204ArgTrp: 1.204 ± 0.04	2.089ArgTyr: 2.089 ± 0.058	0.0ArgXaa: 0.0 ± 0.0
Ser	4.958SerAla: 4.958 ± 0.096	0.866SerCys: 0.866 ± 0.036	4.236SerAsp: 4.236 ± 0.076	4.332SerGlu: 4.332 ± 0.076	3.055SerPhe: 3.055 ± 0.061	6.514SerGly: 6.514 ± 0.107	1.172SerHis: 1.172 ± 0.043	4.372SerIle: 4.372 ± 0.071	2.779SerLys: 2.779 ± 0.06	8.065SerLeu: 8.065 ± 0.129	2.465SerMet: 2.465 ± 0.056	1.535SerAsn: 1.535 ± 0.046	3.328SerPro: 3.328 ± 0.064	1.604SerGln: 1.604 ± 0.048	4.439SerArg: 4.439 ± 0.081	5.429SerSer: 5.429 ± 0.095	2.849SerThr: 2.849 ± 0.063	6.418SerVal: 6.418 ± 0.096	1.066SerTrp: 1.066 ± 0.038	1.899SerTyr: 1.899 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	3.992ThrAla: 3.992 ± 0.087	0.481ThrCys: 0.481 ± 0.028	2.65ThrAsp: 2.65 ± 0.065	2.734ThrGlu: 2.734 ± 0.055	1.701ThrPhe: 1.701 ± 0.046	4.404ThrGly: 4.404 ± 0.071	0.669ThrHis: 0.669 ± 0.029	2.591ThrIle: 2.591 ± 0.065	1.76ThrLys: 1.76 ± 0.05	4.768ThrLeu: 4.768 ± 0.082	1.423ThrMet: 1.423 ± 0.045	1.003ThrAsn: 1.003 ± 0.035	2.25ThrPro: 2.25 ± 0.063	0.829ThrGln: 0.829 ± 0.034	2.064ThrArg: 2.064 ± 0.05	3.096ThrSer: 3.096 ± 0.064	2.167ThrThr: 2.167 ± 0.062	4.865ThrVal: 4.865 ± 0.082	0.535ThrTrp: 0.535 ± 0.025	1.195ThrTyr: 1.195 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	7.294ValAla: 7.294 ± 0.106	0.866ValCys: 0.866 ± 0.035	5.378ValAsp: 5.378 ± 0.084	5.838ValGlu: 5.838 ± 0.106	3.089ValPhe: 3.089 ± 0.067	6.258ValGly: 6.258 ± 0.097	1.229ValHis: 1.229 ± 0.041	4.478ValIle: 4.478 ± 0.083	3.764ValLys: 3.764 ± 0.07	8.279ValLeu: 8.279 ± 0.109	2.347ValMet: 2.347 ± 0.055	2.186ValAsn: 2.186 ± 0.059	3.862ValPro: 3.862 ± 0.085	1.764ValGln: 1.764 ± 0.046	4.688ValArg: 4.688 ± 0.081	6.273ValSer: 6.273 ± 0.098	3.985ValThr: 3.985 ± 0.074	7.337ValVal: 7.337 ± 0.117	0.771ValTrp: 0.771 ± 0.025	1.994ValTyr: 1.994 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.92TrpAla: 0.92 ± 0.036	0.158TrpCys: 0.158 ± 0.012	0.719TrpAsp: 0.719 ± 0.035	0.874TrpGlu: 0.874 ± 0.031	0.517TrpPhe: 0.517 ± 0.029	1.281TrpGly: 1.281 ± 0.043	0.193TrpHis: 0.193 ± 0.016	0.822TrpIle: 0.822 ± 0.038	0.673TrpLys: 0.673 ± 0.03	1.308TrpLeu: 1.308 ± 0.048	0.396TrpMet: 0.396 ± 0.022	0.51TrpAsn: 0.51 ± 0.025	0.488TrpPro: 0.488 ± 0.024	0.313TrpGln: 0.313 ± 0.021	0.959TrpArg: 0.959 ± 0.039	0.822TrpSer: 0.822 ± 0.033	0.621TrpThr: 0.621 ± 0.028	0.736TrpVal: 0.736 ± 0.033	0.24TrpTrp: 0.24 ± 0.02	0.308TrpTyr: 0.308 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.654TyrAla: 1.654 ± 0.045	0.388TyrCys: 0.388 ± 0.022	1.823TyrAsp: 1.823 ± 0.052	1.515TyrGlu: 1.515 ± 0.046	0.977TyrPhe: 0.977 ± 0.034	2.692TyrGly: 2.692 ± 0.062	0.442TyrHis: 0.442 ± 0.024	1.295TyrIle: 1.295 ± 0.042	0.851TyrLys: 0.851 ± 0.035	2.748TyrLeu: 2.748 ± 0.05	0.7TyrMet: 0.7 ± 0.033	0.649TyrAsn: 0.649 ± 0.031	1.313TyrPro: 1.313 ± 0.035	0.613TyrGln: 0.613 ± 0.029	2.356TyrArg: 2.356 ± 0.054	1.802TyrSer: 1.802 ± 0.047	1.046TyrThr: 1.046 ± 0.04	2.018TyrVal: 2.018 ± 0.051	0.349TyrTrp: 0.349 ± 0.021	0.671TyrTyr: 0.671 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2432 proteins (782988 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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