Amino acid dipepetide frequency for Wuhan cricket virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.553AlaAla: 7.553 ± 0.639
2.266AlaCys: 2.266 ± 0.63
1.511AlaAsp: 1.511 ± 0.768
4.532AlaGlu: 4.532 ± 0.979
2.266AlaPhe: 2.266 ± 0.92
2.266AlaGly: 2.266 ± 0.743
3.021AlaHis: 3.021 ± 1.188
4.532AlaIle: 4.532 ± 0.69
4.909AlaLys: 4.909 ± 0.623
5.665AlaLeu: 5.665 ± 0.472
3.021AlaMet: 3.021 ± 0.929
4.532AlaAsn: 4.532 ± 1.156
7.175AlaPro: 7.175 ± 1.321
1.888AlaGln: 1.888 ± 0.802
5.287AlaArg: 5.287 ± 1.418
7.931AlaSer: 7.931 ± 1.541
7.931AlaThr: 7.931 ± 0.915
6.42AlaVal: 6.42 ± 1.907
1.133AlaTrp: 1.133 ± 0.418
3.399AlaTyr: 3.399 ± 0.653
0.0AlaXaa: 0.0 ± 0.0
Cys
0.755CysAla: 0.755 ± 0.384
0.378CysCys: 0.378 ± 0.34
0.378CysAsp: 0.378 ± 0.32
0.378CysGlu: 0.378 ± 0.306
0.755CysPhe: 0.755 ± 0.605
2.266CysGly: 2.266 ± 0.6
0.755CysHis: 0.755 ± 0.632
1.133CysIle: 1.133 ± 0.432
0.378CysLys: 0.378 ± 0.306
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.755CysAsn: 0.755 ± 0.659
1.888CysPro: 1.888 ± 1.199
0.755CysGln: 0.755 ± 0.417
0.378CysArg: 0.378 ± 0.302
0.755CysSer: 0.755 ± 0.366
0.378CysThr: 0.378 ± 0.302
0.755CysVal: 0.755 ± 0.417
0.378CysTrp: 0.378 ± 0.329
0.755CysTyr: 0.755 ± 0.4
0.0CysXaa: 0.0 ± 0.0
Asp
5.287AspAla: 5.287 ± 1.333
0.378AspCys: 0.378 ± 0.302
3.021AspAsp: 3.021 ± 0.839
3.399AspGlu: 3.399 ± 1.18
2.266AspPhe: 2.266 ± 0.893
2.644AspGly: 2.644 ± 0.872
0.755AspHis: 0.755 ± 0.659
1.133AspIle: 1.133 ± 0.436
1.511AspLys: 1.511 ± 0.578
6.798AspLeu: 6.798 ± 1.177
0.378AspMet: 0.378 ± 0.34
2.266AspAsn: 2.266 ± 1.039
5.287AspPro: 5.287 ± 1.092
0.755AspGln: 0.755 ± 0.393
1.133AspArg: 1.133 ± 0.393
5.665AspSer: 5.665 ± 1.497
5.287AspThr: 5.287 ± 0.64
1.511AspVal: 1.511 ± 0.892
1.511AspTrp: 1.511 ± 0.614
3.399AspTyr: 3.399 ± 1.015
0.0AspXaa: 0.0 ± 0.0
Glu
5.665GluAla: 5.665 ± 1.066
0.0GluCys: 0.0 ± 0.0
4.532GluAsp: 4.532 ± 0.954
3.776GluGlu: 3.776 ± 0.443
0.378GluPhe: 0.378 ± 0.316
1.511GluGly: 1.511 ± 0.647
2.266GluHis: 2.266 ± 0.792
2.644GluIle: 2.644 ± 0.368
1.888GluLys: 1.888 ± 0.609
6.798GluLeu: 6.798 ± 1.811
1.888GluMet: 1.888 ± 0.563
0.755GluAsn: 0.755 ± 0.659
4.154GluPro: 4.154 ± 0.868
1.888GluGln: 1.888 ± 0.742
2.266GluArg: 2.266 ± 0.868
1.888GluSer: 1.888 ± 0.771
3.776GluThr: 3.776 ± 1.087
3.021GluVal: 3.021 ± 1.052
0.755GluTrp: 0.755 ± 0.43
0.755GluTyr: 0.755 ± 0.393
0.0GluXaa: 0.0 ± 0.0
Phe
1.888PheAla: 1.888 ± 0.627
0.378PheCys: 0.378 ± 0.329
2.644PheAsp: 2.644 ± 1.053
1.133PheGlu: 1.133 ± 0.674
1.133PhePhe: 1.133 ± 0.435
1.511PheGly: 1.511 ± 0.649
0.755PheHis: 0.755 ± 0.417
2.266PheIle: 2.266 ± 0.842
3.021PheLys: 3.021 ± 0.581
3.399PheLeu: 3.399 ± 1.185
0.0PheMet: 0.0 ± 0.0
2.266PheAsn: 2.266 ± 0.798
2.266PhePro: 2.266 ± 0.645
1.511PheGln: 1.511 ± 0.836
1.511PheArg: 1.511 ± 0.42
5.287PheSer: 5.287 ± 0.898
2.266PheThr: 2.266 ± 0.861
1.133PheVal: 1.133 ± 0.432
0.0PheTrp: 0.0 ± 0.0
0.378PheTyr: 0.378 ± 0.302
0.0PheXaa: 0.0 ± 0.0
Gly
2.266GlyAla: 2.266 ± 0.966
0.0GlyCys: 0.0 ± 0.0
1.888GlyAsp: 1.888 ± 0.806
1.888GlyGlu: 1.888 ± 0.601
1.133GlyPhe: 1.133 ± 0.716
1.133GlyGly: 1.133 ± 0.62
0.378GlyHis: 0.378 ± 0.302
1.133GlyIle: 1.133 ± 0.649
2.644GlyLys: 2.644 ± 0.763
4.154GlyLeu: 4.154 ± 0.724
1.511GlyMet: 1.511 ± 0.544
2.266GlyAsn: 2.266 ± 1.047
1.888GlyPro: 1.888 ± 0.307
3.021GlyGln: 3.021 ± 1.204
0.378GlyArg: 0.378 ± 0.306
2.266GlySer: 2.266 ± 0.56
0.378GlyThr: 0.378 ± 0.302
4.154GlyVal: 4.154 ± 0.927
0.0GlyTrp: 0.0 ± 0.0
1.888GlyTyr: 1.888 ± 0.83
0.0GlyXaa: 0.0 ± 0.0
His
1.511HisAla: 1.511 ± 0.401
0.755HisCys: 0.755 ± 0.398
2.266HisAsp: 2.266 ± 0.864
1.511HisGlu: 1.511 ± 0.437
3.021HisPhe: 3.021 ± 0.763
0.755HisGly: 0.755 ± 0.43
1.888HisHis: 1.888 ± 0.926
2.644HisIle: 2.644 ± 1.132
0.755HisLys: 0.755 ± 0.43
3.399HisLeu: 3.399 ± 0.991
0.0HisMet: 0.0 ± 0.0
1.888HisAsn: 1.888 ± 0.595
3.399HisPro: 3.399 ± 0.818
2.266HisGln: 2.266 ± 0.901
3.399HisArg: 3.399 ± 1.05
1.888HisSer: 1.888 ± 0.609
1.133HisThr: 1.133 ± 0.427
2.644HisVal: 2.644 ± 0.756
1.133HisTrp: 1.133 ± 0.659
0.378HisTyr: 0.378 ± 0.329
0.0HisXaa: 0.0 ± 0.0
Ile
4.909IleAla: 4.909 ± 0.955
0.378IleCys: 0.378 ± 0.302
3.776IleAsp: 3.776 ± 1.144
1.888IleGlu: 1.888 ± 0.617
1.888IlePhe: 1.888 ± 0.892
2.644IleGly: 2.644 ± 0.67
1.888IleHis: 1.888 ± 0.594
1.133IleIle: 1.133 ± 0.427
0.0IleLys: 0.0 ± 0.0
4.532IleLeu: 4.532 ± 1.586
0.755IleMet: 0.755 ± 0.388
1.888IleAsn: 1.888 ± 0.624
3.776IlePro: 3.776 ± 1.438
1.888IleGln: 1.888 ± 0.791
4.532IleArg: 4.532 ± 0.951
3.021IleSer: 3.021 ± 0.952
4.154IleThr: 4.154 ± 0.643
4.154IleVal: 4.154 ± 1.087
0.755IleTrp: 0.755 ± 0.605
1.511IleTyr: 1.511 ± 0.578
0.0IleXaa: 0.0 ± 0.0
Lys
2.266LysAla: 2.266 ± 0.743
0.0LysCys: 0.0 ± 0.0
1.888LysAsp: 1.888 ± 0.68
1.133LysGlu: 1.133 ± 0.675
1.133LysPhe: 1.133 ± 0.626
0.755LysGly: 0.755 ± 0.419
1.511LysHis: 1.511 ± 0.563
3.776LysIle: 3.776 ± 1.041
2.266LysLys: 2.266 ± 0.885
3.399LysLeu: 3.399 ± 1.131
2.644LysMet: 2.644 ± 0.714
2.266LysAsn: 2.266 ± 1.072
3.021LysPro: 3.021 ± 0.784
3.021LysGln: 3.021 ± 0.846
3.399LysArg: 3.399 ± 0.818
1.888LysSer: 1.888 ± 0.915
3.776LysThr: 3.776 ± 1.286
3.776LysVal: 3.776 ± 1.336
0.378LysTrp: 0.378 ± 0.329
1.511LysTyr: 1.511 ± 0.614
0.0LysXaa: 0.0 ± 0.0
Leu
8.308LeuAla: 8.308 ± 0.725
1.133LeuCys: 1.133 ± 0.917
4.532LeuAsp: 4.532 ± 0.859
4.909LeuGlu: 4.909 ± 1.794
2.266LeuPhe: 2.266 ± 0.949
3.399LeuGly: 3.399 ± 1.418
6.798LeuHis: 6.798 ± 1.418
3.021LeuIle: 3.021 ± 0.685
4.532LeuLys: 4.532 ± 1.136
8.308LeuLeu: 8.308 ± 1.258
0.378LeuMet: 0.378 ± 0.302
4.154LeuAsn: 4.154 ± 0.931
9.441LeuPro: 9.441 ± 1.489
4.532LeuGln: 4.532 ± 1.539
4.909LeuArg: 4.909 ± 1.156
9.441LeuSer: 9.441 ± 1.495
6.42LeuThr: 6.42 ± 1.055
4.532LeuVal: 4.532 ± 1.4
0.378LeuTrp: 0.378 ± 0.329
3.399LeuTyr: 3.399 ± 1.073
0.0LeuXaa: 0.0 ± 0.0
Met
3.021MetAla: 3.021 ± 1.062
0.0MetCys: 0.0 ± 0.0
3.021MetAsp: 3.021 ± 0.938
2.266MetGlu: 2.266 ± 0.557
0.755MetPhe: 0.755 ± 0.641
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.133MetIle: 1.133 ± 0.393
0.755MetLys: 0.755 ± 0.388
1.133MetLeu: 1.133 ± 0.576
0.0MetMet: 0.0 ± 0.0
0.378MetAsn: 0.378 ± 0.316
0.378MetPro: 0.378 ± 0.34
0.755MetGln: 0.755 ± 0.364
2.266MetArg: 2.266 ± 0.884
2.266MetSer: 2.266 ± 0.724
1.511MetThr: 1.511 ± 0.353
1.133MetVal: 1.133 ± 0.427
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.021AsnAla: 3.021 ± 0.868
0.755AsnCys: 0.755 ± 0.366
0.755AsnAsp: 0.755 ± 0.68
0.755AsnGlu: 0.755 ± 0.433
1.888AsnPhe: 1.888 ± 0.609
1.511AsnGly: 1.511 ± 0.401
3.021AsnHis: 3.021 ± 0.771
1.511AsnIle: 1.511 ± 0.42
1.511AsnLys: 1.511 ± 0.578
6.42AsnLeu: 6.42 ± 2.295
1.888AsnMet: 1.888 ± 0.338
0.755AsnAsn: 0.755 ± 0.438
4.154AsnPro: 4.154 ± 1.09
4.154AsnGln: 4.154 ± 0.865
2.266AsnArg: 2.266 ± 0.114
0.755AsnSer: 0.755 ± 0.433
3.399AsnThr: 3.399 ± 0.602
3.399AsnVal: 3.399 ± 0.501
0.0AsnTrp: 0.0 ± 0.0
1.511AsnTyr: 1.511 ± 0.635
0.0AsnXaa: 0.0 ± 0.0
Pro
8.308ProAla: 8.308 ± 1.988
0.755ProCys: 0.755 ± 0.418
4.532ProAsp: 4.532 ± 1.566
4.532ProGlu: 4.532 ± 0.984
1.511ProPhe: 1.511 ± 0.564
2.644ProGly: 2.644 ± 0.517
2.266ProHis: 2.266 ± 0.541
5.287ProIle: 5.287 ± 1.744
1.888ProLys: 1.888 ± 0.689
7.553ProLeu: 7.553 ± 1.323
0.0ProMet: 0.0 ± 0.0
2.644ProAsn: 2.644 ± 0.817
5.287ProPro: 5.287 ± 1.836
4.154ProGln: 4.154 ± 1.281
6.798ProArg: 6.798 ± 1.395
6.798ProSer: 6.798 ± 1.152
5.665ProThr: 5.665 ± 1.553
3.399ProVal: 3.399 ± 0.501
0.755ProTrp: 0.755 ± 0.419
2.644ProTyr: 2.644 ± 0.824
0.0ProXaa: 0.0 ± 0.0
Gln
5.287GlnAla: 5.287 ± 1.464
1.133GlnCys: 1.133 ± 0.674
1.511GlnAsp: 1.511 ± 0.375
1.511GlnGlu: 1.511 ± 0.467
1.511GlnPhe: 1.511 ± 0.633
1.133GlnGly: 1.133 ± 0.378
0.755GlnHis: 0.755 ± 0.418
1.511GlnIle: 1.511 ± 0.906
2.266GlnLys: 2.266 ± 0.772
3.399GlnLeu: 3.399 ± 0.835
1.511GlnMet: 1.511 ± 0.463
1.133GlnAsn: 1.133 ± 0.423
3.399GlnPro: 3.399 ± 0.704
1.888GlnGln: 1.888 ± 0.568
2.266GlnArg: 2.266 ± 0.83
1.511GlnSer: 1.511 ± 0.631
3.399GlnThr: 3.399 ± 1.31
2.644GlnVal: 2.644 ± 0.796
1.511GlnTrp: 1.511 ± 1.019
2.644GlnTyr: 2.644 ± 0.896
0.0GlnXaa: 0.0 ± 0.0
Arg
7.175ArgAla: 7.175 ± 1.951
1.133ArgCys: 1.133 ± 0.414
3.399ArgAsp: 3.399 ± 0.969
4.532ArgGlu: 4.532 ± 0.984
2.644ArgPhe: 2.644 ± 1.27
1.133ArgGly: 1.133 ± 0.435
1.511ArgHis: 1.511 ± 0.626
2.266ArgIle: 2.266 ± 0.659
4.532ArgLys: 4.532 ± 0.785
5.287ArgLeu: 5.287 ± 1.249
2.266ArgMet: 2.266 ± 0.82
4.154ArgAsn: 4.154 ± 0.724
4.532ArgPro: 4.532 ± 1.285
1.888ArgGln: 1.888 ± 0.63
3.776ArgArg: 3.776 ± 0.676
1.511ArgSer: 1.511 ± 0.768
4.532ArgThr: 4.532 ± 0.958
2.644ArgVal: 2.644 ± 0.362
0.755ArgTrp: 0.755 ± 0.384
2.644ArgTyr: 2.644 ± 1.034
0.0ArgXaa: 0.0 ± 0.0
Ser
5.665SerAla: 5.665 ± 1.32
1.133SerCys: 1.133 ± 0.667
6.798SerAsp: 6.798 ± 1.184
2.644SerGlu: 2.644 ± 0.905
3.399SerPhe: 3.399 ± 0.551
2.266SerGly: 2.266 ± 0.798
2.644SerHis: 2.644 ± 0.67
3.399SerIle: 3.399 ± 0.867
4.532SerLys: 4.532 ± 0.876
6.798SerLeu: 6.798 ± 1.286
0.755SerMet: 0.755 ± 0.597
3.399SerAsn: 3.399 ± 0.792
4.532SerPro: 4.532 ± 1.126
2.266SerGln: 2.266 ± 0.889
2.644SerArg: 2.644 ± 0.903
6.042SerSer: 6.042 ± 1.476
6.798SerThr: 6.798 ± 0.643
5.287SerVal: 5.287 ± 0.671
1.133SerTrp: 1.133 ± 0.678
0.755SerTyr: 0.755 ± 0.4
0.0SerXaa: 0.0 ± 0.0
Thr
6.42ThrAla: 6.42 ± 1.58
0.755ThrCys: 0.755 ± 0.384
4.532ThrAsp: 4.532 ± 1.74
3.776ThrGlu: 3.776 ± 1.098
3.021ThrPhe: 3.021 ± 0.95
3.021ThrGly: 3.021 ± 0.572
3.399ThrHis: 3.399 ± 0.551
6.42ThrIle: 6.42 ± 1.7
2.644ThrLys: 2.644 ± 0.511
5.287ThrLeu: 5.287 ± 1.054
1.133ThrMet: 1.133 ± 0.448
3.399ThrAsn: 3.399 ± 0.638
5.665ThrPro: 5.665 ± 1.007
1.888ThrGln: 1.888 ± 0.91
4.532ThrArg: 4.532 ± 0.999
6.42ThrSer: 6.42 ± 1.838
8.686ThrThr: 8.686 ± 2.035
2.644ThrVal: 2.644 ± 1.208
1.133ThrTrp: 1.133 ± 0.371
2.266ThrTyr: 2.266 ± 0.408
0.0ThrXaa: 0.0 ± 0.0
Val
4.532ValAla: 4.532 ± 1.026
1.511ValCys: 1.511 ± 0.8
2.644ValAsp: 2.644 ± 0.525
3.776ValGlu: 3.776 ± 1.278
3.021ValPhe: 3.021 ± 0.467
1.133ValGly: 1.133 ± 0.459
1.888ValHis: 1.888 ± 0.594
3.021ValIle: 3.021 ± 0.67
0.755ValLys: 0.755 ± 0.43
4.532ValLeu: 4.532 ± 1.865
1.133ValMet: 1.133 ± 0.414
1.888ValAsn: 1.888 ± 0.898
3.776ValPro: 3.776 ± 0.99
1.888ValGln: 1.888 ± 0.767
6.42ValArg: 6.42 ± 1.075
4.532ValSer: 4.532 ± 1.125
5.287ValThr: 5.287 ± 1.363
2.644ValVal: 2.644 ± 1.18
0.378ValTrp: 0.378 ± 0.316
2.266ValTyr: 2.266 ± 0.911
0.0ValXaa: 0.0 ± 0.0
Trp
0.378TrpAla: 0.378 ± 0.316
1.133TrpCys: 1.133 ± 0.399
0.0TrpAsp: 0.0 ± 0.0
0.755TrpGlu: 0.755 ± 0.388
0.0TrpPhe: 0.0 ± 0.0
0.755TrpGly: 0.755 ± 0.393
0.0TrpHis: 0.0 ± 0.0
0.755TrpIle: 0.755 ± 0.418
1.133TrpLys: 1.133 ± 0.619
2.644TrpLeu: 2.644 ± 0.579
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.755TrpPro: 0.755 ± 0.659
0.0TrpGln: 0.0 ± 0.0
0.755TrpArg: 0.755 ± 0.4
0.755TrpSer: 0.755 ± 0.43
0.755TrpThr: 0.755 ± 0.438
0.755TrpVal: 0.755 ± 0.403
0.378TrpTrp: 0.378 ± 0.329
0.755TrpTyr: 0.755 ± 0.393
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.021TyrAla: 3.021 ± 1.093
0.0TyrCys: 0.0 ± 0.0
0.755TyrAsp: 0.755 ± 0.4
1.511TyrGlu: 1.511 ± 0.65
0.755TyrPhe: 0.755 ± 0.605
1.888TyrGly: 1.888 ± 0.338
1.133TyrHis: 1.133 ± 0.659
0.755TyrIle: 0.755 ± 0.384
1.888TyrLys: 1.888 ± 0.842
5.287TyrLeu: 5.287 ± 0.888
1.133TyrMet: 1.133 ± 0.619
2.644TyrAsn: 2.644 ± 0.583
2.644TyrPro: 2.644 ± 0.763
1.511TyrGln: 1.511 ± 0.628
3.399TyrArg: 3.399 ± 0.861
2.644TyrSer: 2.644 ± 0.615
1.511TyrThr: 1.511 ± 0.644
0.378TyrVal: 0.378 ± 0.34
0.0TyrTrp: 0.0 ± 0.0
1.888TyrTyr: 1.888 ± 0.504
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2649 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski