Amino acid dipepetide frequency for Sanxia sobemo-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.027AlaAla: 3.027 ± 0.205
0.0AlaCys: 0.0 ± 0.0
4.036AlaAsp: 4.036 ± 0.798
5.045AlaGlu: 5.045 ± 0.194
3.027AlaPhe: 3.027 ± 1.403
4.036AlaGly: 4.036 ± 2.417
1.009AlaHis: 1.009 ± 0.604
3.027AlaIle: 3.027 ± 3.011
1.009AlaLys: 1.009 ± 0.604
4.036AlaLeu: 4.036 ± 0.798
3.027AlaMet: 3.027 ± 0.205
1.009AlaAsn: 1.009 ± 0.604
1.009AlaPro: 1.009 ± 1.004
3.027AlaGln: 3.027 ± 1.813
2.018AlaArg: 2.018 ± 2.007
3.027AlaSer: 3.027 ± 0.205
4.036AlaThr: 4.036 ± 0.81
4.036AlaVal: 4.036 ± 0.798
2.018AlaTrp: 2.018 ± 0.399
2.018AlaTyr: 2.018 ± 1.209
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.018CysAsp: 2.018 ± 1.209
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.018CysGly: 2.018 ± 0.399
1.009CysHis: 1.009 ± 0.604
4.036CysIle: 4.036 ± 0.81
2.018CysLys: 2.018 ± 1.209
3.027CysLeu: 3.027 ± 1.403
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
2.018CysGln: 2.018 ± 0.399
2.018CysArg: 2.018 ± 0.399
1.009CysSer: 1.009 ± 0.604
1.009CysThr: 1.009 ± 0.604
3.027CysVal: 3.027 ± 0.205
0.0CysTrp: 0.0 ± 0.0
1.009CysTyr: 1.009 ± 0.604
0.0CysXaa: 0.0 ± 0.0
Asp
2.018AspAla: 2.018 ± 2.007
0.0AspCys: 0.0 ± 0.0
3.027AspAsp: 3.027 ± 3.011
5.045AspGlu: 5.045 ± 1.802
3.027AspPhe: 3.027 ± 0.205
4.036AspGly: 4.036 ± 4.014
3.027AspHis: 3.027 ± 0.205
4.036AspIle: 4.036 ± 0.81
4.036AspLys: 4.036 ± 0.798
3.027AspLeu: 3.027 ± 0.205
1.009AspMet: 1.009 ± 1.004
4.036AspAsn: 4.036 ± 0.798
2.018AspPro: 2.018 ± 0.399
3.027AspGln: 3.027 ± 0.205
1.009AspArg: 1.009 ± 1.004
1.009AspSer: 1.009 ± 1.004
2.018AspThr: 2.018 ± 0.399
1.009AspVal: 1.009 ± 0.604
3.027AspTrp: 3.027 ± 3.011
1.009AspTyr: 1.009 ± 1.004
0.0AspXaa: 0.0 ± 0.0
Glu
2.018GluAla: 2.018 ± 1.209
2.018GluCys: 2.018 ± 0.399
4.036GluAsp: 4.036 ± 0.798
6.054GluGlu: 6.054 ± 2.018
3.027GluPhe: 3.027 ± 1.403
3.027GluGly: 3.027 ± 1.403
2.018GluHis: 2.018 ± 0.399
3.027GluIle: 3.027 ± 0.205
4.036GluLys: 4.036 ± 0.81
3.027GluLeu: 3.027 ± 0.205
3.027GluMet: 3.027 ± 0.457
1.009GluAsn: 1.009 ± 1.004
4.036GluPro: 4.036 ± 0.798
2.018GluGln: 2.018 ± 1.209
3.027GluArg: 3.027 ± 1.813
6.054GluSer: 6.054 ± 2.018
1.009GluThr: 1.009 ± 0.604
5.045GluVal: 5.045 ± 0.194
0.0GluTrp: 0.0 ± 0.0
2.018GluTyr: 2.018 ± 0.399
0.0GluXaa: 0.0 ± 0.0
Phe
1.009PheAla: 1.009 ± 0.604
2.018PheCys: 2.018 ± 0.399
2.018PheAsp: 2.018 ± 2.007
3.027PheGlu: 3.027 ± 0.205
1.009PhePhe: 1.009 ± 1.004
3.027PheGly: 3.027 ± 0.205
1.009PheHis: 1.009 ± 0.604
2.018PheIle: 2.018 ± 2.007
1.009PheLys: 1.009 ± 0.604
6.054PheLeu: 6.054 ± 0.41
2.018PheMet: 2.018 ± 0.399
1.009PheAsn: 1.009 ± 1.004
2.018PhePro: 2.018 ± 2.007
0.0PheGln: 0.0 ± 0.0
3.027PheArg: 3.027 ± 1.403
2.018PheSer: 2.018 ± 0.399
0.0PheThr: 0.0 ± 0.0
3.027PheVal: 3.027 ± 1.813
0.0PheTrp: 0.0 ± 0.0
1.009PheTyr: 1.009 ± 0.604
0.0PheXaa: 0.0 ± 0.0
Gly
4.036GlyAla: 4.036 ± 0.81
1.009GlyCys: 1.009 ± 1.004
2.018GlyAsp: 2.018 ± 2.007
6.054GlyGlu: 6.054 ± 3.626
1.009GlyPhe: 1.009 ± 1.004
5.045GlyGly: 5.045 ± 0.194
0.0GlyHis: 0.0 ± 0.0
2.018GlyIle: 2.018 ± 1.209
3.027GlyLys: 3.027 ± 1.403
4.036GlyLeu: 4.036 ± 0.81
5.045GlyMet: 5.045 ± 3.022
2.018GlyAsn: 2.018 ± 1.209
3.027GlyPro: 3.027 ± 0.205
4.036GlyGln: 4.036 ± 2.417
2.018GlyArg: 2.018 ± 0.399
3.027GlySer: 3.027 ± 1.813
1.009GlyThr: 1.009 ± 0.604
11.1GlyVal: 11.1 ± 1.824
2.018GlyTrp: 2.018 ± 2.007
4.036GlyTyr: 4.036 ± 0.798
0.0GlyXaa: 0.0 ± 0.0
His
2.018HisAla: 2.018 ± 2.007
1.009HisCys: 1.009 ± 0.604
2.018HisAsp: 2.018 ± 1.209
1.009HisGlu: 1.009 ± 0.604
1.009HisPhe: 1.009 ± 1.004
2.018HisGly: 2.018 ± 0.399
0.0HisHis: 0.0 ± 0.0
1.009HisIle: 1.009 ± 0.604
3.027HisLys: 3.027 ± 0.205
1.009HisLeu: 1.009 ± 1.004
1.009HisMet: 1.009 ± 1.004
1.009HisAsn: 1.009 ± 0.604
2.018HisPro: 2.018 ± 0.399
0.0HisGln: 0.0 ± 0.0
4.036HisArg: 4.036 ± 0.798
1.009HisSer: 1.009 ± 0.604
0.0HisThr: 0.0 ± 0.0
6.054HisVal: 6.054 ± 2.018
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.027IleAla: 3.027 ± 3.011
1.009IleCys: 1.009 ± 0.604
2.018IleAsp: 2.018 ± 2.007
3.027IleGlu: 3.027 ± 0.205
3.027IlePhe: 3.027 ± 0.205
5.045IleGly: 5.045 ± 1.414
1.009IleHis: 1.009 ± 1.004
4.036IleIle: 4.036 ± 0.81
5.045IleLys: 5.045 ± 0.194
5.045IleLeu: 5.045 ± 0.194
1.009IleMet: 1.009 ± 0.604
0.0IleAsn: 0.0 ± 0.0
5.045IlePro: 5.045 ± 1.414
0.0IleGln: 0.0 ± 0.0
2.018IleArg: 2.018 ± 0.399
4.036IleSer: 4.036 ± 0.81
3.027IleThr: 3.027 ± 0.205
5.045IleVal: 5.045 ± 1.414
1.009IleTrp: 1.009 ± 1.004
5.045IleTyr: 5.045 ± 0.194
0.0IleXaa: 0.0 ± 0.0
Lys
2.018LysAla: 2.018 ± 0.399
2.018LysCys: 2.018 ± 1.209
1.009LysAsp: 1.009 ± 0.604
1.009LysGlu: 1.009 ± 1.004
2.018LysPhe: 2.018 ± 1.209
4.036LysGly: 4.036 ± 0.798
2.018LysHis: 2.018 ± 0.399
7.064LysIle: 7.064 ± 0.593
7.064LysLys: 7.064 ± 2.623
6.054LysLeu: 6.054 ± 1.197
1.009LysMet: 1.009 ± 0.604
5.045LysAsn: 5.045 ± 1.414
2.018LysPro: 2.018 ± 1.209
4.036LysGln: 4.036 ± 0.798
1.009LysArg: 1.009 ± 1.004
5.045LysSer: 5.045 ± 0.194
4.036LysThr: 4.036 ± 2.417
4.036LysVal: 4.036 ± 2.417
0.0LysTrp: 0.0 ± 0.0
1.009LysTyr: 1.009 ± 0.604
0.0LysXaa: 0.0 ± 0.0
Leu
3.027LeuAla: 3.027 ± 1.403
4.036LeuCys: 4.036 ± 0.798
5.045LeuAsp: 5.045 ± 1.802
4.036LeuGlu: 4.036 ± 0.798
5.045LeuPhe: 5.045 ± 5.018
3.027LeuGly: 3.027 ± 1.813
3.027LeuHis: 3.027 ± 3.011
2.018LeuIle: 2.018 ± 0.399
6.054LeuLys: 6.054 ± 0.41
8.073LeuLeu: 8.073 ± 1.597
4.036LeuMet: 4.036 ± 0.81
2.018LeuAsn: 2.018 ± 0.399
1.009LeuPro: 1.009 ± 0.604
2.018LeuGln: 2.018 ± 1.209
8.073LeuArg: 8.073 ± 1.597
5.045LeuSer: 5.045 ± 3.022
4.036LeuThr: 4.036 ± 0.81
4.036LeuVal: 4.036 ± 0.81
4.036LeuTrp: 4.036 ± 0.798
4.036LeuTyr: 4.036 ± 0.798
0.0LeuXaa: 0.0 ± 0.0
Met
3.027MetAla: 3.027 ± 0.205
0.0MetCys: 0.0 ± 0.0
1.009MetAsp: 1.009 ± 0.604
0.0MetGlu: 0.0 ± 0.0
1.009MetPhe: 1.009 ± 0.604
1.009MetGly: 1.009 ± 1.004
2.018MetHis: 2.018 ± 1.209
2.018MetIle: 2.018 ± 1.209
1.009MetLys: 1.009 ± 0.604
4.036MetLeu: 4.036 ± 0.798
1.009MetMet: 1.009 ± 0.604
3.027MetAsn: 3.027 ± 3.011
1.009MetPro: 1.009 ± 0.604
2.018MetGln: 2.018 ± 0.399
6.054MetArg: 6.054 ± 0.41
4.036MetSer: 4.036 ± 0.81
1.009MetThr: 1.009 ± 1.004
4.036MetVal: 4.036 ± 0.81
3.027MetTrp: 3.027 ± 1.403
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.027AsnAla: 3.027 ± 1.403
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
3.027AsnGlu: 3.027 ± 0.205
2.018AsnPhe: 2.018 ± 1.209
3.027AsnGly: 3.027 ± 1.813
3.027AsnHis: 3.027 ± 1.813
1.009AsnIle: 1.009 ± 1.004
1.009AsnLys: 1.009 ± 1.004
3.027AsnLeu: 3.027 ± 1.403
3.027AsnMet: 3.027 ± 0.359
1.009AsnAsn: 1.009 ± 0.604
3.027AsnPro: 3.027 ± 1.403
1.009AsnGln: 1.009 ± 0.604
3.027AsnArg: 3.027 ± 1.403
1.009AsnSer: 1.009 ± 1.004
1.009AsnThr: 1.009 ± 1.004
5.045AsnVal: 5.045 ± 3.022
1.009AsnTrp: 1.009 ± 1.004
1.009AsnTyr: 1.009 ± 1.004
0.0AsnXaa: 0.0 ± 0.0
Pro
4.036ProAla: 4.036 ± 0.81
2.018ProCys: 2.018 ± 1.209
5.045ProAsp: 5.045 ± 0.194
2.018ProGlu: 2.018 ± 1.209
1.009ProPhe: 1.009 ± 0.604
2.018ProGly: 2.018 ± 0.399
1.009ProHis: 1.009 ± 1.004
2.018ProIle: 2.018 ± 0.399
3.027ProLys: 3.027 ± 1.813
4.036ProLeu: 4.036 ± 2.406
1.009ProMet: 1.009 ± 0.604
1.009ProAsn: 1.009 ± 1.004
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
0.0ProArg: 0.0 ± 0.0
4.036ProSer: 4.036 ± 0.81
2.018ProThr: 2.018 ± 0.399
4.036ProVal: 4.036 ± 2.406
0.0ProTrp: 0.0 ± 0.0
2.018ProTyr: 2.018 ± 0.399
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
2.018GlnCys: 2.018 ± 1.209
0.0GlnAsp: 0.0 ± 0.0
4.036GlnGlu: 4.036 ± 0.798
1.009GlnPhe: 1.009 ± 0.604
0.0GlnGly: 0.0 ± 0.0
3.027GlnHis: 3.027 ± 1.813
3.027GlnIle: 3.027 ± 0.205
2.018GlnLys: 2.018 ± 0.399
1.009GlnLeu: 1.009 ± 1.004
1.009GlnMet: 1.009 ± 1.004
3.027GlnAsn: 3.027 ± 1.813
3.027GlnPro: 3.027 ± 0.205
4.036GlnGln: 4.036 ± 0.798
2.018GlnArg: 2.018 ± 0.399
4.036GlnSer: 4.036 ± 0.81
1.009GlnThr: 1.009 ± 1.004
3.027GlnVal: 3.027 ± 1.813
2.018GlnTrp: 2.018 ± 0.399
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.018ArgAla: 2.018 ± 0.399
0.0ArgCys: 0.0 ± 0.0
3.027ArgAsp: 3.027 ± 1.403
4.036ArgGlu: 4.036 ± 0.798
2.018ArgPhe: 2.018 ± 2.007
2.018ArgGly: 2.018 ± 1.209
1.009ArgHis: 1.009 ± 1.004
9.082ArgIle: 9.082 ± 0.616
2.018ArgLys: 2.018 ± 1.209
5.045ArgLeu: 5.045 ± 0.194
1.009ArgMet: 1.009 ± 0.604
3.027ArgAsn: 3.027 ± 1.403
0.0ArgPro: 0.0 ± 0.0
1.009ArgGln: 1.009 ± 1.004
2.018ArgArg: 2.018 ± 0.399
3.027ArgSer: 3.027 ± 0.205
7.064ArgThr: 7.064 ± 2.623
4.036ArgVal: 4.036 ± 2.406
2.018ArgTrp: 2.018 ± 0.399
2.018ArgTyr: 2.018 ± 0.399
0.0ArgXaa: 0.0 ± 0.0
Ser
8.073SerAla: 8.073 ± 1.619
3.027SerCys: 3.027 ± 1.813
2.018SerAsp: 2.018 ± 1.209
2.018SerGlu: 2.018 ± 1.209
3.027SerPhe: 3.027 ± 1.813
9.082SerGly: 9.082 ± 2.224
2.018SerHis: 2.018 ± 0.399
0.0SerIle: 0.0 ± 0.0
4.036SerLys: 4.036 ± 2.417
5.045SerLeu: 5.045 ± 1.802
4.036SerMet: 4.036 ± 0.798
0.0SerAsn: 0.0 ± 0.0
5.045SerPro: 5.045 ± 0.194
5.045SerGln: 5.045 ± 0.194
4.036SerArg: 4.036 ± 0.81
7.064SerSer: 7.064 ± 2.201
1.009SerThr: 1.009 ± 0.604
5.045SerVal: 5.045 ± 1.802
0.0SerTrp: 0.0 ± 0.0
2.018SerTyr: 2.018 ± 0.399
0.0SerXaa: 0.0 ± 0.0
Thr
1.009ThrAla: 1.009 ± 0.604
1.009ThrCys: 1.009 ± 0.604
2.018ThrAsp: 2.018 ± 0.399
3.027ThrGlu: 3.027 ± 1.813
0.0ThrPhe: 0.0 ± 0.0
2.018ThrGly: 2.018 ± 0.399
1.009ThrHis: 1.009 ± 0.604
2.018ThrIle: 2.018 ± 0.399
1.009ThrLys: 1.009 ± 0.604
4.036ThrLeu: 4.036 ± 0.81
1.009ThrMet: 1.009 ± 0.604
3.027ThrAsn: 3.027 ± 1.813
1.009ThrPro: 1.009 ± 0.604
2.018ThrGln: 2.018 ± 1.209
4.036ThrArg: 4.036 ± 2.417
6.054ThrSer: 6.054 ± 1.197
4.036ThrThr: 4.036 ± 2.417
4.036ThrVal: 4.036 ± 0.798
3.027ThrTrp: 3.027 ± 1.813
2.018ThrTyr: 2.018 ± 0.399
0.0ThrXaa: 0.0 ± 0.0
Val
7.064ValAla: 7.064 ± 2.623
2.018ValCys: 2.018 ± 0.399
7.064ValAsp: 7.064 ± 5.417
6.054ValGlu: 6.054 ± 1.197
3.027ValPhe: 3.027 ± 0.205
6.054ValGly: 6.054 ± 3.626
0.0ValHis: 0.0 ± 0.0
3.027ValIle: 3.027 ± 1.813
8.073ValLys: 8.073 ± 1.619
6.054ValLeu: 6.054 ± 2.018
3.027ValMet: 3.027 ± 0.205
6.054ValAsn: 6.054 ± 0.41
2.018ValPro: 2.018 ± 0.399
2.018ValGln: 2.018 ± 2.007
3.027ValArg: 3.027 ± 0.205
6.054ValSer: 6.054 ± 0.41
6.054ValThr: 6.054 ± 3.626
8.073ValVal: 8.073 ± 3.227
0.0ValTrp: 0.0 ± 0.0
2.018ValTyr: 2.018 ± 1.209
0.0ValXaa: 0.0 ± 0.0
Trp
1.009TrpAla: 1.009 ± 0.604
0.0TrpCys: 0.0 ± 0.0
1.009TrpAsp: 1.009 ± 1.004
1.009TrpGlu: 1.009 ± 1.004
0.0TrpPhe: 0.0 ± 0.0
1.009TrpGly: 1.009 ± 0.604
0.0TrpHis: 0.0 ± 0.0
1.009TrpIle: 1.009 ± 1.004
1.009TrpLys: 1.009 ± 1.004
2.018TrpLeu: 2.018 ± 2.007
2.018TrpMet: 2.018 ± 2.007
1.009TrpAsn: 1.009 ± 1.004
1.009TrpPro: 1.009 ± 0.604
2.018TrpGln: 2.018 ± 0.399
0.0TrpArg: 0.0 ± 0.0
2.018TrpSer: 2.018 ± 0.399
3.027TrpThr: 3.027 ± 0.205
3.027TrpVal: 3.027 ± 0.205
0.0TrpTrp: 0.0 ± 0.0
1.009TrpTyr: 1.009 ± 1.004
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.018TyrAla: 2.018 ± 0.399
1.009TyrCys: 1.009 ± 1.004
2.018TyrAsp: 2.018 ± 2.007
1.009TyrGlu: 1.009 ± 1.004
1.009TyrPhe: 1.009 ± 0.604
4.036TyrGly: 4.036 ± 2.417
2.018TyrHis: 2.018 ± 0.399
3.027TyrIle: 3.027 ± 0.205
2.018TyrLys: 2.018 ± 2.007
4.036TyrLeu: 4.036 ± 2.417
1.009TyrMet: 1.009 ± 1.004
1.009TyrAsn: 1.009 ± 1.004
2.018TyrPro: 2.018 ± 0.399
0.0TyrGln: 0.0 ± 0.0
3.027TyrArg: 3.027 ± 0.205
3.027TyrSer: 3.027 ± 0.205
1.009TyrThr: 1.009 ± 0.604
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.018TyrTyr: 2.018 ± 0.399
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (992 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski