Amino acid dipepetide frequency for Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.394AlaAla: 7.394 ± 0.133	0.933AlaCys: 0.933 ± 0.039	4.152AlaAsp: 4.152 ± 0.067	4.936AlaGlu: 4.936 ± 0.08	3.388AlaPhe: 3.388 ± 0.061	5.963AlaGly: 5.963 ± 0.08	1.962AlaHis: 1.962 ± 0.05	6.116AlaIle: 6.116 ± 0.085	4.76AlaLys: 4.76 ± 0.08	9.526AlaLeu: 9.526 ± 0.11	2.361AlaMet: 2.361 ± 0.056	3.248AlaAsn: 3.248 ± 0.069	2.926AlaPro: 2.926 ± 0.057	4.589AlaGln: 4.589 ± 0.081	3.446AlaArg: 3.446 ± 0.062	5.004AlaSer: 5.004 ± 0.067	4.491AlaThr: 4.491 ± 0.073	5.506AlaVal: 5.506 ± 0.097	1.124AlaTrp: 1.124 ± 0.031	2.684AlaTyr: 2.684 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.746CysAla: 0.746 ± 0.029	0.145CysCys: 0.145 ± 0.015	0.489CysAsp: 0.489 ± 0.022	0.532CysGlu: 0.532 ± 0.024	0.459CysPhe: 0.459 ± 0.021	0.769CysGly: 0.769 ± 0.027	0.299CysHis: 0.299 ± 0.021	0.693CysIle: 0.693 ± 0.031	0.351CysLys: 0.351 ± 0.019	0.962CysLeu: 0.962 ± 0.037	0.254CysMet: 0.254 ± 0.016	0.305CysAsn: 0.305 ± 0.015	0.409CysPro: 0.409 ± 0.02	0.428CysGln: 0.428 ± 0.02	0.425CysArg: 0.425 ± 0.017	0.645CysSer: 0.645 ± 0.021	0.458CysThr: 0.458 ± 0.021	0.693CysVal: 0.693 ± 0.032	0.126CysTrp: 0.126 ± 0.011	0.311CysTyr: 0.311 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.43AspAla: 4.43 ± 0.085	0.4AspCys: 0.4 ± 0.021	2.625AspAsp: 2.625 ± 0.058	3.235AspGlu: 3.235 ± 0.063	2.385AspPhe: 2.385 ± 0.063	3.128AspGly: 3.128 ± 0.061	1.532AspHis: 1.532 ± 0.034	3.801AspIle: 3.801 ± 0.065	2.314AspLys: 2.314 ± 0.045	5.685AspLeu: 5.685 ± 0.08	1.201AspMet: 1.201 ± 0.034	1.808AspAsn: 1.808 ± 0.045	2.111AspPro: 2.111 ± 0.04	3.353AspGln: 3.353 ± 0.068	2.335AspArg: 2.335 ± 0.047	2.583AspSer: 2.583 ± 0.046	2.503AspThr: 2.503 ± 0.058	3.703AspVal: 3.703 ± 0.064	0.772AspTrp: 0.772 ± 0.031	2.007AspTyr: 2.007 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	4.567GluAla: 4.567 ± 0.069	0.403GluCys: 0.403 ± 0.022	2.542GluAsp: 2.542 ± 0.048	2.748GluGlu: 2.748 ± 0.064	2.117GluPhe: 2.117 ± 0.044	3.111GluGly: 3.111 ± 0.065	1.741GluHis: 1.741 ± 0.045	4.159GluIle: 4.159 ± 0.071	3.63GluLys: 3.63 ± 0.064	5.862GluLeu: 5.862 ± 0.087	1.392GluMet: 1.392 ± 0.029	2.664GluAsn: 2.664 ± 0.059	1.675GluPro: 1.675 ± 0.042	4.22GluGln: 4.22 ± 0.073	2.938GluArg: 2.938 ± 0.072	2.947GluSer: 2.947 ± 0.061	2.885GluThr: 2.885 ± 0.048	3.43GluVal: 3.43 ± 0.061	0.763GluTrp: 0.763 ± 0.028	1.79GluTyr: 1.79 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.536PheAla: 3.536 ± 0.067	0.495PheCys: 0.495 ± 0.023	2.687PheAsp: 2.687 ± 0.051	2.652PheGlu: 2.652 ± 0.049	1.968PhePhe: 1.968 ± 0.053	3.215PheGly: 3.215 ± 0.054	0.868PheHis: 0.868 ± 0.027	3.154PheIle: 3.154 ± 0.075	2.457PheLys: 2.457 ± 0.047	3.915PheLeu: 3.915 ± 0.069	1.062PheMet: 1.062 ± 0.033	2.21PheAsn: 2.21 ± 0.045	1.515PhePro: 1.515 ± 0.046	1.657PheGln: 1.657 ± 0.042	1.511PheArg: 1.511 ± 0.038	3.179PheSer: 3.179 ± 0.06	2.12PheThr: 2.12 ± 0.056	2.583PheVal: 2.583 ± 0.049	0.663PheTrp: 0.663 ± 0.021	1.568PheTyr: 1.568 ± 0.05	0.0PheXaa: 0.0 ± 0.0
Gly	5.093GlyAla: 5.093 ± 0.087	0.814GlyCys: 0.814 ± 0.034	2.955GlyAsp: 2.955 ± 0.064	3.502GlyGlu: 3.502 ± 0.066	3.377GlyPhe: 3.377 ± 0.065	4.747GlyGly: 4.747 ± 0.091	1.676GlyHis: 1.676 ± 0.051	4.909GlyIle: 4.909 ± 0.09	3.568GlyLys: 3.568 ± 0.048	7.402GlyLeu: 7.402 ± 0.099	1.826GlyMet: 1.826 ± 0.045	2.4GlyAsn: 2.4 ± 0.058	1.547GlyPro: 1.547 ± 0.035	3.365GlyGln: 3.365 ± 0.079	2.93GlyArg: 2.93 ± 0.062	3.95GlySer: 3.95 ± 0.078	3.554GlyThr: 3.554 ± 0.077	4.836GlyVal: 4.836 ± 0.079	0.962GlyTrp: 0.962 ± 0.031	2.541GlyTyr: 2.541 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	2.153HisAla: 2.153 ± 0.053	0.266HisCys: 0.266 ± 0.018	1.366HisAsp: 1.366 ± 0.033	1.275HisGlu: 1.275 ± 0.032	1.254HisPhe: 1.254 ± 0.035	1.659HisGly: 1.659 ± 0.044	0.939HisHis: 0.939 ± 0.036	1.733HisIle: 1.733 ± 0.042	0.997HisLys: 0.997 ± 0.032	2.86HisLeu: 2.86 ± 0.066	0.53HisMet: 0.53 ± 0.021	0.82HisAsn: 0.82 ± 0.032	1.433HisPro: 1.433 ± 0.036	1.523HisGln: 1.523 ± 0.034	1.125HisArg: 1.125 ± 0.037	1.453HisSer: 1.453 ± 0.033	1.184HisThr: 1.184 ± 0.039	1.568HisVal: 1.568 ± 0.039	0.388HisTrp: 0.388 ± 0.019	1.03HisTyr: 1.03 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	6.672IleAla: 6.672 ± 0.106	0.73IleCys: 0.73 ± 0.029	4.273IleAsp: 4.273 ± 0.072	4.722IleGlu: 4.722 ± 0.079	2.958IlePhe: 2.958 ± 0.067	4.966IleGly: 4.966 ± 0.085	1.716IleHis: 1.716 ± 0.041	4.16IleIle: 4.16 ± 0.08	3.425IleLys: 3.425 ± 0.052	6.788IleLeu: 6.788 ± 0.101	1.585IleMet: 1.585 ± 0.052	2.985IleAsn: 2.985 ± 0.053	3.002IlePro: 3.002 ± 0.051	3.895IleGln: 3.895 ± 0.071	3.19IleArg: 3.19 ± 0.063	4.539IleSer: 4.539 ± 0.088	3.473IleThr: 3.473 ± 0.062	4.391IleVal: 4.391 ± 0.08	0.783IleTrp: 0.783 ± 0.033	2.172IleTyr: 2.172 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.509LysAla: 4.509 ± 0.075	0.281LysCys: 0.281 ± 0.02	2.8LysAsp: 2.8 ± 0.058	2.694LysGlu: 2.694 ± 0.059	1.911LysPhe: 1.911 ± 0.045	2.991LysGly: 2.991 ± 0.053	1.264LysHis: 1.264 ± 0.041	4.005LysIle: 4.005 ± 0.067	3.195LysLys: 3.195 ± 0.058	5.205LysLeu: 5.205 ± 0.066	1.358LysMet: 1.358 ± 0.032	2.732LysAsn: 2.732 ± 0.068	2.204LysPro: 2.204 ± 0.042	3.288LysGln: 3.288 ± 0.062	2.502LysArg: 2.502 ± 0.049	3.039LysSer: 3.039 ± 0.058	3.255LysThr: 3.255 ± 0.052	3.462LysVal: 3.462 ± 0.073	0.558LysTrp: 0.558 ± 0.025	1.648LysTyr: 1.648 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	9.275LeuAla: 9.275 ± 0.123	1.097LeuCys: 1.097 ± 0.024	5.902LeuAsp: 5.902 ± 0.08	5.744LeuGlu: 5.744 ± 0.097	4.225LeuPhe: 4.225 ± 0.09	7.352LeuGly: 7.352 ± 0.103	2.224LeuHis: 2.224 ± 0.053	7.47LeuIle: 7.47 ± 0.094	6.588LeuLys: 6.588 ± 0.082	10.024LeuLeu: 10.024 ± 0.15	2.73LeuMet: 2.73 ± 0.052	5.597LeuAsn: 5.597 ± 0.095	4.668LeuPro: 4.668 ± 0.067	4.632LeuGln: 4.632 ± 0.073	4.275LeuArg: 4.275 ± 0.075	7.635LeuSer: 7.635 ± 0.1	5.631LeuThr: 5.631 ± 0.084	6.317LeuVal: 6.317 ± 0.095	1.228LeuTrp: 1.228 ± 0.03	2.888LeuTyr: 2.888 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.129MetAla: 2.129 ± 0.057	0.217MetCys: 0.217 ± 0.014	1.046MetAsp: 1.046 ± 0.032	0.889MetGlu: 0.889 ± 0.031	0.9MetPhe: 0.9 ± 0.034	1.708MetGly: 1.708 ± 0.043	0.585MetHis: 0.585 ± 0.026	1.8MetIle: 1.8 ± 0.044	1.324MetLys: 1.324 ± 0.033	2.675MetLeu: 2.675 ± 0.047	0.858MetMet: 0.858 ± 0.037	1.299MetAsn: 1.299 ± 0.036	1.115MetPro: 1.115 ± 0.035	1.422MetGln: 1.422 ± 0.038	1.162MetArg: 1.162 ± 0.036	2.006MetSer: 2.006 ± 0.05	1.589MetThr: 1.589 ± 0.036	1.606MetVal: 1.606 ± 0.047	0.234MetTrp: 0.234 ± 0.014	0.575MetTyr: 0.575 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	3.608AsnAla: 3.608 ± 0.06	0.345AsnCys: 0.345 ± 0.017	2.19AsnAsp: 2.19 ± 0.056	2.215AsnGlu: 2.215 ± 0.053	1.854AsnPhe: 1.854 ± 0.047	2.681AsnGly: 2.681 ± 0.046	1.092AsnHis: 1.092 ± 0.028	3.338AsnIle: 3.338 ± 0.07	2.063AsnLys: 2.063 ± 0.046	4.463AsnLeu: 4.463 ± 0.067	1.037AsnMet: 1.037 ± 0.036	1.912AsnAsn: 1.912 ± 0.07	2.282AsnPro: 2.282 ± 0.046	2.629AsnGln: 2.629 ± 0.055	1.857AsnArg: 1.857 ± 0.036	2.521AsnSer: 2.521 ± 0.062	2.535AsnThr: 2.535 ± 0.058	2.675AsnVal: 2.675 ± 0.044	0.563AsnTrp: 0.563 ± 0.024	1.549AsnTyr: 1.549 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	3.177ProAla: 3.177 ± 0.062	0.267ProCys: 0.267 ± 0.016	2.294ProAsp: 2.294 ± 0.045	3.183ProGlu: 3.183 ± 0.064	1.805ProPhe: 1.805 ± 0.042	1.678ProGly: 1.678 ± 0.042	0.993ProHis: 0.993 ± 0.032	2.623ProIle: 2.623 ± 0.049	2.331ProLys: 2.331 ± 0.053	4.152ProLeu: 4.152 ± 0.066	0.982ProMet: 0.982 ± 0.032	1.831ProAsn: 1.831 ± 0.042	1.145ProPro: 1.145 ± 0.041	2.141ProGln: 2.141 ± 0.05	1.446ProArg: 1.446 ± 0.04	2.382ProSer: 2.382 ± 0.049	2.155ProThr: 2.155 ± 0.043	3.179ProVal: 3.179 ± 0.06	0.489ProTrp: 0.489 ± 0.023	1.433ProTyr: 1.433 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	5.048GlnAla: 5.048 ± 0.082	0.414GlnCys: 0.414 ± 0.022	2.629GlnAsp: 2.629 ± 0.047	2.578GlnGlu: 2.578 ± 0.049	2.178GlnPhe: 2.178 ± 0.046	3.262GlnGly: 3.262 ± 0.071	1.895GlnHis: 1.895 ± 0.039	3.791GlnIle: 3.791 ± 0.056	2.921GlnLys: 2.921 ± 0.047	6.021GlnLeu: 6.021 ± 0.097	1.239GlnMet: 1.239 ± 0.032	2.481GlnAsn: 2.481 ± 0.061	2.364GlnPro: 2.364 ± 0.05	4.444GlnGln: 4.444 ± 0.109	2.684GlnArg: 2.684 ± 0.055	3.319GlnSer: 3.319 ± 0.057	2.818GlnThr: 2.818 ± 0.054	3.428GlnVal: 3.428 ± 0.059	0.716GlnTrp: 0.716 ± 0.03	1.887GlnTyr: 1.887 ± 0.049	0.0GlnXaa: 0.0 ± 0.0
Arg	3.324ArgAla: 3.324 ± 0.057	0.387ArgCys: 0.387 ± 0.019	2.319ArgAsp: 2.319 ± 0.052	2.632ArgGlu: 2.632 ± 0.054	2.228ArgPhe: 2.228 ± 0.054	2.485ArgGly: 2.485 ± 0.055	1.253ArgHis: 1.253 ± 0.033	3.189ArgIle: 3.189 ± 0.05	2.109ArgLys: 2.109 ± 0.044	5.096ArgLeu: 5.096 ± 0.079	1.098ArgMet: 1.098 ± 0.035	1.76ArgAsn: 1.76 ± 0.052	1.689ArgPro: 1.689 ± 0.044	2.455ArgGln: 2.455 ± 0.054	2.125ArgArg: 2.125 ± 0.051	2.38ArgSer: 2.38 ± 0.052	1.994ArgThr: 1.994 ± 0.037	2.93ArgVal: 2.93 ± 0.062	0.566ArgTrp: 0.566 ± 0.026	1.831ArgTyr: 1.831 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	4.892SerAla: 4.892 ± 0.059	0.577SerCys: 0.577 ± 0.025	3.089SerAsp: 3.089 ± 0.053	3.263SerGlu: 3.263 ± 0.066	2.916SerPhe: 2.916 ± 0.057	4.493SerGly: 4.493 ± 0.066	1.602SerHis: 1.602 ± 0.039	4.491SerIle: 4.491 ± 0.078	3.123SerLys: 3.123 ± 0.061	6.693SerLeu: 6.693 ± 0.082	1.634SerMet: 1.634 ± 0.037	2.706SerAsn: 2.706 ± 0.055	2.413SerPro: 2.413 ± 0.05	3.077SerGln: 3.077 ± 0.066	2.623SerArg: 2.623 ± 0.05	4.401SerSer: 4.401 ± 0.086	3.611SerThr: 3.611 ± 0.074	3.987SerVal: 3.987 ± 0.064	0.77SerTrp: 0.77 ± 0.026	2.012SerTyr: 2.012 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	4.702ThrAla: 4.702 ± 0.077	0.439ThrCys: 0.439 ± 0.023	2.696ThrAsp: 2.696 ± 0.058	2.835ThrGlu: 2.835 ± 0.056	2.105ThrPhe: 2.105 ± 0.041	4.207ThrGly: 4.207 ± 0.079	1.393ThrHis: 1.393 ± 0.036	3.375ThrIle: 3.375 ± 0.064	2.202ThrLys: 2.202 ± 0.051	6.146ThrLeu: 6.146 ± 0.094	1.075ThrMet: 1.075 ± 0.032	1.908ThrAsn: 1.908 ± 0.045	2.766ThrPro: 2.766 ± 0.061	2.996ThrGln: 2.996 ± 0.065	2.254ThrArg: 2.254 ± 0.049	3.326ThrSer: 3.326 ± 0.073	3.289ThrThr: 3.289 ± 0.081	3.603ThrVal: 3.603 ± 0.071	0.618ThrTrp: 0.618 ± 0.021	1.577ThrTyr: 1.577 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	5.619ValAla: 5.619 ± 0.088	0.732ValCys: 0.732 ± 0.028	3.58ValAsp: 3.58 ± 0.058	3.926ValGlu: 3.926 ± 0.056	2.781ValPhe: 2.781 ± 0.055	4.538ValGly: 4.538 ± 0.079	1.325ValHis: 1.325 ± 0.037	4.728ValIle: 4.728 ± 0.07	3.4ValLys: 3.4 ± 0.063	6.758ValLeu: 6.758 ± 0.1	1.845ValMet: 1.845 ± 0.052	2.863ValAsn: 2.863 ± 0.056	2.655ValPro: 2.655 ± 0.046	2.921ValGln: 2.921 ± 0.064	2.717ValArg: 2.717 ± 0.047	4.169ValSer: 4.169 ± 0.049	3.642ValThr: 3.642 ± 0.065	4.776ValVal: 4.776 ± 0.075	0.772ValTrp: 0.772 ± 0.028	1.799ValTyr: 1.799 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.85TrpAla: 0.85 ± 0.034	0.164TrpCys: 0.164 ± 0.015	0.521TrpAsp: 0.521 ± 0.021	0.471TrpGlu: 0.471 ± 0.023	0.659TrpPhe: 0.659 ± 0.023	0.758TrpGly: 0.758 ± 0.033	0.355TrpHis: 0.355 ± 0.019	0.955TrpIle: 0.955 ± 0.036	0.65TrpLys: 0.65 ± 0.026	1.633TrpLeu: 1.633 ± 0.046	0.416TrpMet: 0.416 ± 0.02	0.597TrpAsn: 0.597 ± 0.027	0.379TrpPro: 0.379 ± 0.019	0.902TrpGln: 0.902 ± 0.036	0.599TrpArg: 0.599 ± 0.026	0.794TrpSer: 0.794 ± 0.026	0.642TrpThr: 0.642 ± 0.025	0.868TrpVal: 0.868 ± 0.031	0.179TrpTrp: 0.179 ± 0.012	0.372TrpTyr: 0.372 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.784TyrAla: 2.784 ± 0.054	0.397TyrCys: 0.397 ± 0.019	1.756TyrAsp: 1.756 ± 0.054	1.552TyrGlu: 1.552 ± 0.038	1.547TyrPhe: 1.547 ± 0.04	2.245TyrGly: 2.245 ± 0.048	0.837TyrHis: 0.837 ± 0.028	1.937TyrIle: 1.937 ± 0.044	1.494TyrLys: 1.494 ± 0.035	3.637TyrLeu: 3.637 ± 0.068	0.653TyrMet: 0.653 ± 0.024	1.279TyrAsn: 1.279 ± 0.035	1.389TyrPro: 1.389 ± 0.041	2.181TyrGln: 2.181 ± 0.054	1.706TyrArg: 1.706 ± 0.046	2.102TyrSer: 2.102 ± 0.042	1.683TyrThr: 1.683 ± 0.042	2.006TyrVal: 2.006 ± 0.044	0.487TyrTrp: 0.487 ± 0.022	1.083TyrTyr: 1.083 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3263 proteins (1044193 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---