Amino acid dipepetide frequency for Roseivivax isoporae LMG 25204

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.384AlaAla: 21.384 ± 0.197	1.121AlaCys: 1.121 ± 0.03	7.936AlaAsp: 7.936 ± 0.089	9.358AlaGlu: 9.358 ± 0.103	4.486AlaPhe: 4.486 ± 0.064	12.721AlaGly: 12.721 ± 0.106	2.582AlaHis: 2.582 ± 0.044	5.636AlaIle: 5.636 ± 0.068	2.294AlaLys: 2.294 ± 0.054	15.932AlaLeu: 15.932 ± 0.148	3.826AlaMet: 3.826 ± 0.054	2.256AlaAsn: 2.256 ± 0.049	7.162AlaPro: 7.162 ± 0.08	4.269AlaGln: 4.269 ± 0.063	12.044AlaArg: 12.044 ± 0.106	5.323AlaSer: 5.323 ± 0.062	6.542AlaThr: 6.542 ± 0.076	9.42AlaVal: 9.42 ± 0.092	1.75AlaTrp: 1.75 ± 0.036	2.453AlaTyr: 2.453 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	1.122CysAla: 1.122 ± 0.029	0.113CysCys: 0.113 ± 0.009	0.576CysAsp: 0.576 ± 0.02	0.351CysGlu: 0.351 ± 0.016	0.284CysPhe: 0.284 ± 0.013	0.948CysGly: 0.948 ± 0.029	0.273CysHis: 0.273 ± 0.017	0.367CysIle: 0.367 ± 0.016	0.129CysLys: 0.129 ± 0.008	0.842CysLeu: 0.842 ± 0.023	0.141CysMet: 0.141 ± 0.01	0.198CysAsn: 0.198 ± 0.013	0.474CysPro: 0.474 ± 0.02	0.169CysGln: 0.169 ± 0.01	0.6CysArg: 0.6 ± 0.02	0.346CysSer: 0.346 ± 0.017	0.447CysThr: 0.447 ± 0.019	0.629CysVal: 0.629 ± 0.022	0.107CysTrp: 0.107 ± 0.009	0.176CysTyr: 0.176 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.961AspAla: 8.961 ± 0.097	0.46AspCys: 0.46 ± 0.017	3.724AspAsp: 3.724 ± 0.074	3.384AspGlu: 3.384 ± 0.049	2.202AspPhe: 2.202 ± 0.043	6.385AspGly: 6.385 ± 0.099	1.356AspHis: 1.356 ± 0.033	2.856AspIle: 2.856 ± 0.043	1.044AspLys: 1.044 ± 0.03	6.704AspLeu: 6.704 ± 0.069	1.608AspMet: 1.608 ± 0.036	1.059AspAsn: 1.059 ± 0.03	4.227AspPro: 4.227 ± 0.057	1.392AspGln: 1.392 ± 0.034	5.628AspArg: 5.628 ± 0.074	2.025AspSer: 2.025 ± 0.04	3.247AspThr: 3.247 ± 0.062	4.522AspVal: 4.522 ± 0.067	1.236AspTrp: 1.236 ± 0.031	1.454AspTyr: 1.454 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	9.167GluAla: 9.167 ± 0.088	0.343GluCys: 0.343 ± 0.017	3.681GluAsp: 3.681 ± 0.06	3.535GluGlu: 3.535 ± 0.062	1.546GluPhe: 1.546 ± 0.034	5.225GluGly: 5.225 ± 0.072	1.002GluHis: 1.002 ± 0.029	3.404GluIle: 3.404 ± 0.05	1.489GluLys: 1.489 ± 0.041	4.72GluLeu: 4.72 ± 0.068	1.754GluMet: 1.754 ± 0.041	1.382GluAsn: 1.382 ± 0.034	2.596GluPro: 2.596 ± 0.046	1.507GluGln: 1.507 ± 0.041	4.796GluArg: 4.796 ± 0.064	2.095GluSer: 2.095 ± 0.04	4.009GluThr: 4.009 ± 0.055	4.509GluVal: 4.509 ± 0.058	0.638GluTrp: 0.638 ± 0.022	0.884GluTyr: 0.884 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.541PheAla: 4.541 ± 0.065	0.374PheCys: 0.374 ± 0.017	2.819PheAsp: 2.819 ± 0.046	2.15PheGlu: 2.15 ± 0.039	1.351PhePhe: 1.351 ± 0.038	3.711PheGly: 3.711 ± 0.051	0.731PheHis: 0.731 ± 0.023	1.234PheIle: 1.234 ± 0.032	0.569PheLys: 0.569 ± 0.02	3.458PheLeu: 3.458 ± 0.054	0.759PheMet: 0.759 ± 0.024	0.822PheAsn: 0.822 ± 0.025	1.506PhePro: 1.506 ± 0.033	0.827PheGln: 0.827 ± 0.024	2.417PheArg: 2.417 ± 0.048	1.775PheSer: 1.775 ± 0.038	1.847PheThr: 1.847 ± 0.046	2.841PheVal: 2.841 ± 0.048	0.572PheTrp: 0.572 ± 0.024	0.815PheTyr: 0.815 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	11.98GlyAla: 11.98 ± 0.095	0.842GlyCys: 0.842 ± 0.029	5.304GlyAsp: 5.304 ± 0.089	4.607GlyGlu: 4.607 ± 0.064	3.565GlyPhe: 3.565 ± 0.049	8.455GlyGly: 8.455 ± 0.132	2.037GlyHis: 2.037 ± 0.042	4.603GlyIle: 4.603 ± 0.062	2.107GlyLys: 2.107 ± 0.044	9.682GlyLeu: 9.682 ± 0.089	2.514GlyMet: 2.514 ± 0.049	1.94GlyAsn: 1.94 ± 0.048	4.364GlyPro: 4.364 ± 0.057	2.859GlyGln: 2.859 ± 0.045	7.363GlyArg: 7.363 ± 0.095	4.284GlySer: 4.284 ± 0.061	5.73GlyThr: 5.73 ± 0.081	6.504GlyVal: 6.504 ± 0.076	1.544GlyTrp: 1.544 ± 0.036	2.249GlyTyr: 2.249 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.698HisAla: 2.698 ± 0.052	0.212HisCys: 0.212 ± 0.013	1.319HisAsp: 1.319 ± 0.032	1.068HisGlu: 1.068 ± 0.025	0.759HisPhe: 0.759 ± 0.024	2.063HisGly: 2.063 ± 0.045	0.526HisHis: 0.526 ± 0.022	0.65HisIle: 0.65 ± 0.021	0.307HisLys: 0.307 ± 0.015	2.06HisLeu: 2.06 ± 0.04	0.474HisMet: 0.474 ± 0.02	0.358HisAsn: 0.358 ± 0.016	1.413HisPro: 1.413 ± 0.033	0.469HisGln: 0.469 ± 0.016	1.525HisArg: 1.525 ± 0.036	0.705HisSer: 0.705 ± 0.023	0.73HisThr: 0.73 ± 0.023	1.818HisVal: 1.818 ± 0.034	0.317HisTrp: 0.317 ± 0.014	0.484HisTyr: 0.484 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.901IleAla: 6.901 ± 0.071	0.47IleCys: 0.47 ± 0.021	3.341IleAsp: 3.341 ± 0.051	3.043IleGlu: 3.043 ± 0.048	1.522IlePhe: 1.522 ± 0.039	4.415IleGly: 4.415 ± 0.059	0.774IleHis: 0.774 ± 0.025	1.425IleIle: 1.425 ± 0.037	0.782IleLys: 0.782 ± 0.025	4.527IleLeu: 4.527 ± 0.064	0.849IleMet: 0.849 ± 0.03	0.931IleAsn: 0.931 ± 0.027	1.956IlePro: 1.956 ± 0.039	0.907IleGln: 0.907 ± 0.028	3.063IleArg: 3.063 ± 0.045	2.122IleSer: 2.122 ± 0.042	2.229IleThr: 2.229 ± 0.04	3.874IleVal: 3.874 ± 0.055	0.575IleTrp: 0.575 ± 0.023	0.955IleTyr: 0.955 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	2.592LysAla: 2.592 ± 0.053	0.134LysCys: 0.134 ± 0.009	1.144LysAsp: 1.144 ± 0.03	1.057LysGlu: 1.057 ± 0.031	0.561LysPhe: 0.561 ± 0.02	1.794LysGly: 1.794 ± 0.042	0.369LysHis: 0.369 ± 0.016	0.983LysIle: 0.983 ± 0.025	0.676LysLys: 0.676 ± 0.024	1.936LysLeu: 1.936 ± 0.045	0.55LysMet: 0.55 ± 0.02	0.456LysAsn: 0.456 ± 0.019	1.193LysPro: 1.193 ± 0.034	0.481LysGln: 0.481 ± 0.021	1.614LysArg: 1.614 ± 0.037	1.169LysSer: 1.169 ± 0.03	1.272LysThr: 1.272 ± 0.033	1.711LysVal: 1.711 ± 0.04	0.275LysTrp: 0.275 ± 0.014	0.401LysTyr: 0.401 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	14.527LeuAla: 14.527 ± 0.143	1.0LeuCys: 1.0 ± 0.026	6.763LeuAsp: 6.763 ± 0.078	5.298LeuGlu: 5.298 ± 0.06	3.491LeuPhe: 3.491 ± 0.056	9.053LeuGly: 9.053 ± 0.086	1.84LeuHis: 1.84 ± 0.038	4.114LeuIle: 4.114 ± 0.064	2.209LeuLys: 2.209 ± 0.042	9.098LeuLeu: 9.098 ± 0.112	2.48LeuMet: 2.48 ± 0.043	2.169LeuAsn: 2.169 ± 0.043	5.805LeuPro: 5.805 ± 0.067	2.43LeuGln: 2.43 ± 0.047	8.094LeuArg: 8.094 ± 0.084	6.583LeuSer: 6.583 ± 0.079	5.686LeuThr: 5.686 ± 0.062	7.953LeuVal: 7.953 ± 0.086	1.376LeuTrp: 1.376 ± 0.033	1.9LeuTyr: 1.9 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.343MetAla: 3.343 ± 0.047	0.174MetCys: 0.174 ± 0.01	1.345MetAsp: 1.345 ± 0.033	1.196MetGlu: 1.196 ± 0.032	0.736MetPhe: 0.736 ± 0.021	2.084MetGly: 2.084 ± 0.043	0.449MetHis: 0.449 ± 0.016	1.331MetIle: 1.331 ± 0.033	0.79MetLys: 0.79 ± 0.026	2.486MetLeu: 2.486 ± 0.049	0.677MetMet: 0.677 ± 0.023	0.675MetAsn: 0.675 ± 0.021	1.53MetPro: 1.53 ± 0.033	0.866MetGln: 0.866 ± 0.024	1.976MetArg: 1.976 ± 0.039	1.558MetSer: 1.558 ± 0.035	2.044MetThr: 2.044 ± 0.041	1.709MetVal: 1.709 ± 0.037	0.226MetTrp: 0.226 ± 0.014	0.281MetTyr: 0.281 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.79AsnAla: 2.79 ± 0.047	0.207AsnCys: 0.207 ± 0.013	1.265AsnAsp: 1.265 ± 0.038	0.96AsnGlu: 0.96 ± 0.028	0.745AsnPhe: 0.745 ± 0.026	2.01AsnGly: 2.01 ± 0.05	0.397AsnHis: 0.397 ± 0.017	0.994AsnIle: 0.994 ± 0.028	0.364AsnLys: 0.364 ± 0.018	2.05AsnLeu: 2.05 ± 0.045	0.546AsnMet: 0.546 ± 0.018	0.478AsnAsn: 0.478 ± 0.021	1.516AsnPro: 1.516 ± 0.034	0.501AsnGln: 0.501 ± 0.018	1.592AsnArg: 1.592 ± 0.034	0.806AsnSer: 0.806 ± 0.026	1.093AsnThr: 1.093 ± 0.034	1.685AsnVal: 1.685 ± 0.043	0.331AsnTrp: 0.331 ± 0.017	0.493AsnTyr: 0.493 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	6.964ProAla: 6.964 ± 0.085	0.364ProCys: 0.364 ± 0.018	4.478ProAsp: 4.478 ± 0.065	4.488ProGlu: 4.488 ± 0.062	1.936ProPhe: 1.936 ± 0.036	5.437ProGly: 5.437 ± 0.053	1.133ProHis: 1.133 ± 0.031	1.877ProIle: 1.877 ± 0.036	1.063ProLys: 1.063 ± 0.031	4.857ProLeu: 4.857 ± 0.057	1.185ProMet: 1.185 ± 0.03	1.057ProAsn: 1.057 ± 0.03	2.653ProPro: 2.653 ± 0.049	1.505ProGln: 1.505 ± 0.032	3.643ProArg: 3.643 ± 0.056	2.303ProSer: 2.303 ± 0.039	2.303ProThr: 2.303 ± 0.039	4.648ProVal: 4.648 ± 0.062	0.706ProTrp: 0.706 ± 0.026	1.086ProTyr: 1.086 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	3.638GlnAla: 3.638 ± 0.053	0.173GlnCys: 0.173 ± 0.013	1.685GlnAsp: 1.685 ± 0.037	1.493GlnGlu: 1.493 ± 0.035	0.855GlnPhe: 0.855 ± 0.028	2.377GlnGly: 2.377 ± 0.041	0.481GlnHis: 0.481 ± 0.017	1.507GlnIle: 1.507 ± 0.036	0.76GlnLys: 0.76 ± 0.027	2.233GlnLeu: 2.233 ± 0.044	0.811GlnMet: 0.811 ± 0.023	0.689GlnAsn: 0.689 ± 0.024	1.409GlnPro: 1.409 ± 0.031	0.829GlnGln: 0.829 ± 0.03	1.959GlnArg: 1.959 ± 0.039	1.475GlnSer: 1.475 ± 0.036	1.474GlnThr: 1.474 ± 0.033	2.27GlnVal: 2.27 ± 0.041	0.335GlnTrp: 0.335 ± 0.016	0.474GlnTyr: 0.474 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	10.995ArgAla: 10.995 ± 0.101	0.488ArgCys: 0.488 ± 0.018	5.239ArgAsp: 5.239 ± 0.072	4.187ArgGlu: 4.187 ± 0.06	2.891ArgPhe: 2.891 ± 0.049	5.832ArgGly: 5.832 ± 0.07	1.873ArgHis: 1.873 ± 0.04	4.205ArgIle: 4.205 ± 0.054	1.698ArgLys: 1.698 ± 0.04	8.583ArgLeu: 8.583 ± 0.096	2.138ArgMet: 2.138 ± 0.038	1.641ArgAsn: 1.641 ± 0.037	4.182ArgPro: 4.182 ± 0.061	2.331ArgGln: 2.331 ± 0.043	6.797ArgArg: 6.797 ± 0.101	3.292ArgSer: 3.292 ± 0.051	3.832ArgThr: 3.832 ± 0.06	5.748ArgVal: 5.748 ± 0.067	1.087ArgTrp: 1.087 ± 0.025	1.587ArgTyr: 1.587 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.759SerAla: 5.759 ± 0.073	0.378SerCys: 0.378 ± 0.019	3.063SerAsp: 3.063 ± 0.052	2.672SerGlu: 2.672 ± 0.043	2.002SerPhe: 2.002 ± 0.04	5.298SerGly: 5.298 ± 0.072	0.913SerHis: 0.913 ± 0.027	1.957SerIle: 1.957 ± 0.038	0.936SerLys: 0.936 ± 0.023	4.448SerLeu: 4.448 ± 0.067	1.209SerMet: 1.209 ± 0.027	1.043SerAsn: 1.043 ± 0.034	2.284SerPro: 2.284 ± 0.049	1.169SerGln: 1.169 ± 0.032	3.272SerArg: 3.272 ± 0.049	2.124SerSer: 2.124 ± 0.045	2.148SerThr: 2.148 ± 0.037	3.732SerVal: 3.732 ± 0.054	0.622SerTrp: 0.622 ± 0.021	1.161SerTyr: 1.161 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.484ThrAla: 6.484 ± 0.069	0.465ThrCys: 0.465 ± 0.02	3.314ThrAsp: 3.314 ± 0.056	3.089ThrGlu: 3.089 ± 0.053	2.051ThrPhe: 2.051 ± 0.037	5.942ThrGly: 5.942 ± 0.075	1.051ThrHis: 1.051 ± 0.027	2.383ThrIle: 2.383 ± 0.045	0.908ThrLys: 0.908 ± 0.028	6.483ThrLeu: 6.483 ± 0.082	1.178ThrMet: 1.178 ± 0.029	1.029ThrAsn: 1.029 ± 0.032	3.356ThrPro: 3.356 ± 0.048	1.339ThrGln: 1.339 ± 0.032	3.999ThrArg: 3.999 ± 0.045	2.371ThrSer: 2.371 ± 0.044	2.614ThrThr: 2.614 ± 0.05	4.323ThrVal: 4.323 ± 0.069	0.792ThrTrp: 0.792 ± 0.026	1.198ThrTyr: 1.198 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	10.591ValAla: 10.591 ± 0.097	0.623ValCys: 0.623 ± 0.02	4.196ValAsp: 4.196 ± 0.056	4.536ValGlu: 4.536 ± 0.063	2.83ValPhe: 2.83 ± 0.054	5.672ValGly: 5.672 ± 0.07	1.415ValHis: 1.415 ± 0.035	3.748ValIle: 3.748 ± 0.055	1.521ValLys: 1.521 ± 0.037	8.083ValLeu: 8.083 ± 0.083	1.961ValMet: 1.961 ± 0.042	1.815ValAsn: 1.815 ± 0.041	4.307ValPro: 4.307 ± 0.059	1.97ValGln: 1.97 ± 0.042	5.307ValArg: 5.307 ± 0.073	4.096ValSer: 4.096 ± 0.061	5.179ValThr: 5.179 ± 0.077	6.216ValVal: 6.216 ± 0.078	0.996ValTrp: 0.996 ± 0.031	1.469ValTyr: 1.469 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.433TrpAla: 1.433 ± 0.041	0.136TrpCys: 0.136 ± 0.008	0.801TrpAsp: 0.801 ± 0.025	0.647TrpGlu: 0.647 ± 0.022	0.518TrpPhe: 0.518 ± 0.02	1.048TrpGly: 1.048 ± 0.036	0.341TrpHis: 0.341 ± 0.016	0.71TrpIle: 0.71 ± 0.021	0.343TrpLys: 0.343 ± 0.018	1.615TrpLeu: 1.615 ± 0.036	0.416TrpMet: 0.416 ± 0.019	0.363TrpAsn: 0.363 ± 0.017	0.732TrpPro: 0.732 ± 0.027	0.595TrpGln: 0.595 ± 0.023	1.279TrpArg: 1.279 ± 0.029	0.795TrpSer: 0.795 ± 0.025	0.917TrpThr: 0.917 ± 0.028	0.866TrpVal: 0.866 ± 0.024	0.223TrpTrp: 0.223 ± 0.012	0.254TrpTyr: 0.254 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.626TyrAla: 2.626 ± 0.043	0.216TyrCys: 0.216 ± 0.012	1.48TyrAsp: 1.48 ± 0.035	1.167TyrGlu: 1.167 ± 0.034	0.788TyrPhe: 0.788 ± 0.024	2.064TyrGly: 2.064 ± 0.038	0.413TyrHis: 0.413 ± 0.018	0.678TyrIle: 0.678 ± 0.024	0.377TyrLys: 0.377 ± 0.017	2.074TyrLeu: 2.074 ± 0.045	0.398TyrMet: 0.398 ± 0.018	0.462TyrAsn: 0.462 ± 0.018	1.02TyrPro: 1.02 ± 0.025	0.513TyrGln: 0.513 ± 0.022	1.655TyrArg: 1.655 ± 0.033	0.943TyrSer: 0.943 ± 0.025	1.024TyrThr: 1.024 ± 0.031	1.555TyrVal: 1.555 ± 0.033	0.324TyrTrp: 0.324 ± 0.018	0.516TyrTyr: 0.516 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4626 proteins (1446104 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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