Amino acid dipepetide frequency for Wuhan house centipede virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.772AlaAla: 5.772 ± 2.31
0.722AlaCys: 0.722 ± 0.323
1.443AlaAsp: 1.443 ± 0.645
4.329AlaGlu: 4.329 ± 0.553
2.165AlaPhe: 2.165 ± 0.968
4.329AlaGly: 4.329 ± 1.861
0.722AlaHis: 0.722 ± 0.323
4.329AlaIle: 4.329 ± 0.951
3.608AlaLys: 3.608 ± 1.614
3.608AlaLeu: 3.608 ± 0.898
2.165AlaMet: 2.165 ± 3.035
3.608AlaAsn: 3.608 ± 1.614
3.608AlaPro: 3.608 ± 2.183
1.443AlaGln: 1.443 ± 0.645
5.051AlaArg: 5.051 ± 3.715
5.772AlaSer: 5.772 ± 1.688
5.772AlaThr: 5.772 ± 0.791
4.329AlaVal: 4.329 ± 1.126
0.722AlaTrp: 0.722 ± 0.323
2.886AlaTyr: 2.886 ± 0.676
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.722CysAsp: 0.722 ± 0.323
0.0CysGlu: 0.0 ± 0.0
0.722CysPhe: 0.722 ± 0.323
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.722CysIle: 0.722 ± 0.323
0.0CysLys: 0.0 ± 0.0
0.722CysLeu: 0.722 ± 0.323
0.722CysMet: 0.722 ± 0.323
1.443CysAsn: 1.443 ± 0.62
0.722CysPro: 0.722 ± 0.323
0.0CysGln: 0.0 ± 0.0
0.722CysArg: 0.722 ± 0.323
2.886CysSer: 2.886 ± 1.291
0.722CysThr: 0.722 ± 0.323
1.443CysVal: 1.443 ± 0.645
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.886AspAla: 2.886 ± 2.4
0.722AspCys: 0.722 ± 0.323
4.329AspAsp: 4.329 ± 1.167
2.886AspGlu: 2.886 ± 1.291
0.0AspPhe: 0.0 ± 0.0
7.215AspGly: 7.215 ± 1.705
0.722AspHis: 0.722 ± 0.323
4.329AspIle: 4.329 ± 0.951
5.051AspLys: 5.051 ± 0.322
5.772AspLeu: 5.772 ± 1.374
2.886AspMet: 2.886 ± 0.676
0.722AspAsn: 0.722 ± 0.323
4.329AspPro: 4.329 ± 1.126
0.722AspGln: 0.722 ± 0.323
1.443AspArg: 1.443 ± 0.645
4.329AspSer: 4.329 ± 1.861
2.165AspThr: 2.165 ± 0.563
4.329AspVal: 4.329 ± 1.936
1.443AspTrp: 1.443 ± 0.645
2.165AspTyr: 2.165 ± 0.968
0.0AspXaa: 0.0 ± 0.0
Glu
2.886GluAla: 2.886 ± 1.291
0.722GluCys: 0.722 ± 0.323
4.329GluAsp: 4.329 ± 0.951
5.051GluGlu: 5.051 ± 1.459
0.722GluPhe: 0.722 ± 0.323
2.165GluGly: 2.165 ± 0.563
0.722GluHis: 0.722 ± 0.323
2.165GluIle: 2.165 ± 0.563
2.165GluLys: 2.165 ± 0.968
3.608GluLeu: 3.608 ± 1.14
0.0GluMet: 0.0 ± 0.0
0.722GluAsn: 0.722 ± 0.323
3.608GluPro: 3.608 ± 0.852
3.608GluGln: 3.608 ± 1.614
2.165GluArg: 2.165 ± 0.968
0.722GluSer: 0.722 ± 0.323
4.329GluThr: 4.329 ± 0.553
1.443GluVal: 1.443 ± 0.62
0.0GluTrp: 0.0 ± 0.0
2.886GluTyr: 2.886 ± 1.291
0.0GluXaa: 0.0 ± 0.0
Phe
2.886PheAla: 2.886 ± 1.291
0.0PheCys: 0.0 ± 0.0
4.329PheAsp: 4.329 ± 1.126
0.722PheGlu: 0.722 ± 0.323
0.0PhePhe: 0.0 ± 0.0
0.722PheGly: 0.722 ± 0.323
0.722PheHis: 0.722 ± 0.323
2.886PheIle: 2.886 ± 1.291
2.886PheLys: 2.886 ± 1.291
1.443PheLeu: 1.443 ± 0.645
0.0PheMet: 0.0 ± 0.0
2.886PheAsn: 2.886 ± 1.291
1.443PhePro: 1.443 ± 0.62
0.0PheGln: 0.0 ± 0.0
1.443PheArg: 1.443 ± 0.645
0.0PheSer: 0.0 ± 0.0
1.443PheThr: 1.443 ± 0.62
3.608PheVal: 3.608 ± 2.021
0.0PheTrp: 0.0 ± 0.0
0.722PheTyr: 0.722 ± 0.323
0.0PheXaa: 0.0 ± 0.0
Gly
1.443GlyAla: 1.443 ± 0.645
0.722GlyCys: 0.722 ± 0.323
6.494GlyAsp: 6.494 ± 0.501
2.886GlyGlu: 2.886 ± 1.291
1.443GlyPhe: 1.443 ± 0.645
4.329GlyGly: 4.329 ± 1.126
0.722GlyHis: 0.722 ± 0.323
2.886GlyIle: 2.886 ± 1.241
3.608GlyLys: 3.608 ± 0.898
4.329GlyLeu: 4.329 ± 0.553
2.165GlyMet: 2.165 ± 1.41
5.772GlyAsn: 5.772 ± 2.482
1.443GlyPro: 1.443 ± 0.62
2.886GlyGln: 2.886 ± 1.155
5.051GlyArg: 5.051 ± 1.843
2.165GlySer: 2.165 ± 1.41
7.937GlyThr: 7.937 ± 2.71
1.443GlyVal: 1.443 ± 0.62
0.0GlyTrp: 0.0 ± 0.0
5.051GlyTyr: 5.051 ± 1.843
0.0GlyXaa: 0.0 ± 0.0
His
2.165HisAla: 2.165 ± 0.968
0.0HisCys: 0.0 ± 0.0
2.886HisAsp: 2.886 ± 0.676
0.0HisGlu: 0.0 ± 0.0
0.722HisPhe: 0.722 ± 0.323
0.722HisGly: 0.722 ± 0.323
0.722HisHis: 0.722 ± 0.323
0.0HisIle: 0.0 ± 0.0
0.722HisLys: 0.722 ± 0.323
0.722HisLeu: 0.722 ± 0.323
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.443HisPro: 1.443 ± 0.645
2.886HisGln: 2.886 ± 1.291
2.165HisArg: 2.165 ± 0.968
1.443HisSer: 1.443 ± 0.645
1.443HisThr: 1.443 ± 1.2
1.443HisVal: 1.443 ± 0.645
0.722HisTrp: 0.722 ± 0.813
2.165HisTyr: 2.165 ± 0.997
0.0HisXaa: 0.0 ± 0.0
Ile
2.886IleAla: 2.886 ± 3.576
0.0IleCys: 0.0 ± 0.0
2.165IleAsp: 2.165 ± 0.968
8.658IleGlu: 8.658 ± 0.615
1.443IlePhe: 1.443 ± 0.645
5.051IleGly: 5.051 ± 1.459
1.443IleHis: 1.443 ± 0.645
3.608IleIle: 3.608 ± 0.898
4.329IleLys: 4.329 ± 1.167
2.165IleLeu: 2.165 ± 0.997
1.443IleMet: 1.443 ± 0.62
2.165IleAsn: 2.165 ± 1.41
4.329IlePro: 4.329 ± 1.126
2.165IleGln: 2.165 ± 0.968
7.215IleArg: 7.215 ± 0.292
2.165IleSer: 2.165 ± 0.997
5.772IleThr: 5.772 ± 3.152
0.722IleVal: 0.722 ± 0.323
0.722IleTrp: 0.722 ± 0.323
1.443IleTyr: 1.443 ± 0.62
0.0IleXaa: 0.0 ± 0.0
Lys
5.772LysAla: 5.772 ± 1.761
1.443LysCys: 1.443 ± 0.645
3.608LysAsp: 3.608 ± 1.614
2.165LysGlu: 2.165 ± 0.968
1.443LysPhe: 1.443 ± 1.627
4.329LysGly: 4.329 ± 1.936
3.608LysHis: 3.608 ± 0.898
2.886LysIle: 2.886 ± 0.676
3.608LysLys: 3.608 ± 1.614
5.051LysLeu: 5.051 ± 1.459
0.0LysMet: 0.0 ± 0.0
1.443LysAsn: 1.443 ± 0.62
2.886LysPro: 2.886 ± 1.291
2.886LysGln: 2.886 ± 0.676
2.886LysArg: 2.886 ± 0.676
4.329LysSer: 4.329 ± 0.951
5.772LysThr: 5.772 ± 1.352
4.329LysVal: 4.329 ± 1.167
0.722LysTrp: 0.722 ± 0.323
2.886LysTyr: 2.886 ± 1.291
0.0LysXaa: 0.0 ± 0.0
Leu
4.329LeuAla: 4.329 ± 1.167
0.0LeuCys: 0.0 ± 0.0
4.329LeuAsp: 4.329 ± 0.951
0.722LeuGlu: 0.722 ± 0.323
4.329LeuPhe: 4.329 ± 1.936
4.329LeuGly: 4.329 ± 0.553
1.443LeuHis: 1.443 ± 0.645
5.051LeuIle: 5.051 ± 1.999
5.051LeuLys: 5.051 ± 1.459
7.215LeuLeu: 7.215 ± 1.705
1.443LeuMet: 1.443 ± 0.769
2.886LeuAsn: 2.886 ± 2.051
4.329LeuPro: 4.329 ± 2.446
0.722LeuGln: 0.722 ± 0.813
6.494LeuArg: 6.494 ± 1.511
7.215LeuSer: 7.215 ± 0.865
3.608LeuThr: 3.608 ± 1.614
5.051LeuVal: 5.051 ± 1.137
1.443LeuTrp: 1.443 ± 0.645
2.886LeuTyr: 2.886 ± 1.291
0.0LeuXaa: 0.0 ± 0.0
Met
0.722MetAla: 0.722 ± 0.323
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.722MetPhe: 0.722 ± 0.323
0.722MetGly: 0.722 ± 0.323
0.722MetHis: 0.722 ± 0.323
1.443MetIle: 1.443 ± 0.645
2.165MetLys: 2.165 ± 0.563
1.443MetLeu: 1.443 ± 0.645
2.165MetMet: 2.165 ± 0.968
0.0MetAsn: 0.0 ± 0.0
1.443MetPro: 1.443 ± 0.62
0.722MetGln: 0.722 ± 0.323
3.608MetArg: 3.608 ± 2.752
4.329MetSer: 4.329 ± 0.553
3.608MetThr: 3.608 ± 1.14
0.722MetVal: 0.722 ± 0.813
0.0MetTrp: 0.0 ± 0.0
1.443MetTyr: 1.443 ± 0.62
0.0MetXaa: 0.0 ± 0.0
Asn
5.051AsnAla: 5.051 ± 1.747
0.0AsnCys: 0.0 ± 0.0
2.886AsnAsp: 2.886 ± 0.87
0.0AsnGlu: 0.0 ± 0.0
1.443AsnPhe: 1.443 ± 0.62
2.165AsnGly: 2.165 ± 1.41
1.443AsnHis: 1.443 ± 2.895
4.329AsnIle: 4.329 ± 1.126
3.608AsnLys: 3.608 ± 1.14
3.608AsnLeu: 3.608 ± 1.614
1.443AsnMet: 1.443 ± 0.603
5.772AsnAsn: 5.772 ± 3.996
5.772AsnPro: 5.772 ± 1.742
2.886AsnGln: 2.886 ± 2.051
4.329AsnArg: 4.329 ± 2.94
2.165AsnSer: 2.165 ± 0.997
2.165AsnThr: 2.165 ± 0.563
4.329AsnVal: 4.329 ± 1.167
1.443AsnTrp: 1.443 ± 1.2
2.165AsnTyr: 2.165 ± 0.968
0.0AsnXaa: 0.0 ± 0.0
Pro
3.608ProAla: 3.608 ± 1.14
0.0ProCys: 0.0 ± 0.0
1.443ProAsp: 1.443 ± 0.645
1.443ProGlu: 1.443 ± 0.645
1.443ProPhe: 1.443 ± 0.62
5.051ProGly: 5.051 ± 0.322
0.0ProHis: 0.0 ± 0.0
4.329ProIle: 4.329 ± 1.936
2.886ProLys: 2.886 ± 1.291
4.329ProLeu: 4.329 ± 1.167
0.722ProMet: 0.722 ± 0.323
5.772ProAsn: 5.772 ± 1.742
2.886ProPro: 2.886 ± 1.155
2.165ProGln: 2.165 ± 1.47
6.494ProArg: 6.494 ± 2.07
4.329ProSer: 4.329 ± 2.446
4.329ProThr: 4.329 ± 2.272
2.886ProVal: 2.886 ± 2.4
0.0ProTrp: 0.0 ± 0.0
1.443ProTyr: 1.443 ± 0.62
0.0ProXaa: 0.0 ± 0.0
Gln
2.886GlnAla: 2.886 ± 0.676
0.0GlnCys: 0.0 ± 0.0
0.722GlnAsp: 0.722 ± 0.323
0.722GlnGlu: 0.722 ± 0.323
1.443GlnPhe: 1.443 ± 0.645
0.0GlnGly: 0.0 ± 0.0
1.443GlnHis: 1.443 ± 0.645
0.722GlnIle: 0.722 ± 0.813
1.443GlnLys: 1.443 ± 0.62
3.608GlnLeu: 3.608 ± 1.14
2.165GlnMet: 2.165 ± 0.968
0.722GlnAsn: 0.722 ± 0.323
0.0GlnPro: 0.0 ± 0.0
1.443GlnGln: 1.443 ± 1.2
2.165GlnArg: 2.165 ± 0.997
3.608GlnSer: 3.608 ± 0.852
2.886GlnThr: 2.886 ± 2.4
4.329GlnVal: 4.329 ± 1.994
0.0GlnTrp: 0.0 ± 0.0
2.886GlnTyr: 2.886 ± 0.676
0.0GlnXaa: 0.0 ± 0.0
Arg
2.165ArgAla: 2.165 ± 0.563
0.0ArgCys: 0.0 ± 0.0
4.329ArgAsp: 4.329 ± 2.272
2.886ArgGlu: 2.886 ± 1.155
2.165ArgPhe: 2.165 ± 0.563
2.886ArgGly: 2.886 ± 0.87
0.722ArgHis: 0.722 ± 0.323
5.772ArgIle: 5.772 ± 0.791
3.608ArgLys: 3.608 ± 0.898
7.937ArgLeu: 7.937 ± 3.109
0.722ArgMet: 0.722 ± 0.323
6.494ArgAsn: 6.494 ± 2.642
5.051ArgPro: 5.051 ± 1.137
2.165ArgGln: 2.165 ± 0.997
2.886ArgArg: 2.886 ± 0.87
6.494ArgSer: 6.494 ± 1.511
6.494ArgThr: 6.494 ± 1.999
3.608ArgVal: 3.608 ± 3.836
0.722ArgTrp: 0.722 ± 0.323
2.165ArgTyr: 2.165 ± 0.968
0.0ArgXaa: 0.0 ± 0.0
Ser
5.772SerAla: 5.772 ± 0.332
2.886SerCys: 2.886 ± 1.291
2.165SerAsp: 2.165 ± 1.47
2.886SerGlu: 2.886 ± 1.291
0.722SerPhe: 0.722 ± 0.323
7.215SerGly: 7.215 ± 2.506
1.443SerHis: 1.443 ± 0.645
5.772SerIle: 5.772 ± 1.853
4.329SerLys: 4.329 ± 1.167
1.443SerLeu: 1.443 ± 0.62
1.443SerMet: 1.443 ± 0.62
6.494SerAsn: 6.494 ± 1.511
3.608SerPro: 3.608 ± 1.614
0.722SerGln: 0.722 ± 0.323
2.886SerArg: 2.886 ± 2.051
3.608SerSer: 3.608 ± 1.14
7.215SerThr: 7.215 ± 1.692
5.051SerVal: 5.051 ± 1.099
0.0SerTrp: 0.0 ± 0.0
3.608SerTyr: 3.608 ± 1.614
0.0SerXaa: 0.0 ± 0.0
Thr
2.886ThrAla: 2.886 ± 1.241
2.165ThrCys: 2.165 ± 0.968
4.329ThrAsp: 4.329 ± 1.936
4.329ThrGlu: 4.329 ± 1.167
2.165ThrPhe: 2.165 ± 0.563
7.937ThrGly: 7.937 ± 3.182
1.443ThrHis: 1.443 ± 0.645
5.051ThrIle: 5.051 ± 2.624
4.329ThrLys: 4.329 ± 1.126
5.772ThrLeu: 5.772 ± 1.739
2.165ThrMet: 2.165 ± 0.968
5.772ThrAsn: 5.772 ± 4.8
3.608ThrPro: 3.608 ± 2.558
2.886ThrGln: 2.886 ± 0.87
4.329ThrArg: 4.329 ± 2.94
5.772ThrSer: 5.772 ± 0.332
8.658ThrThr: 8.658 ± 2.825
6.494ThrVal: 6.494 ± 1.511
0.722ThrTrp: 0.722 ± 0.323
3.608ThrTyr: 3.608 ± 0.846
0.0ThrXaa: 0.0 ± 0.0
Val
5.772ValAla: 5.772 ± 1.688
1.443ValCys: 1.443 ± 0.62
6.494ValAsp: 6.494 ± 2.905
2.165ValGlu: 2.165 ± 0.968
2.886ValPhe: 2.886 ± 1.291
2.886ValGly: 2.886 ± 2.851
1.443ValHis: 1.443 ± 0.62
2.165ValIle: 2.165 ± 0.563
4.329ValLys: 4.329 ± 1.936
3.608ValLeu: 3.608 ± 2.558
2.165ValMet: 2.165 ± 0.997
1.443ValAsn: 1.443 ± 0.62
3.608ValPro: 3.608 ± 0.898
0.0ValGln: 0.0 ± 0.0
4.329ValArg: 4.329 ± 1.994
4.329ValSer: 4.329 ± 1.414
5.772ValThr: 5.772 ± 1.739
5.051ValVal: 5.051 ± 1.137
0.722ValTrp: 0.722 ± 0.813
2.165ValTyr: 2.165 ± 0.997
0.0ValXaa: 0.0 ± 0.0
Trp
1.443TrpAla: 1.443 ± 1.2
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.722TrpGlu: 0.722 ± 0.323
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.722TrpHis: 0.722 ± 0.323
0.722TrpIle: 0.722 ± 0.813
0.0TrpLys: 0.0 ± 0.0
2.165TrpLeu: 2.165 ± 0.968
0.722TrpMet: 0.722 ± 0.813
0.722TrpAsn: 0.722 ± 0.323
0.722TrpPro: 0.722 ± 0.323
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.722TrpSer: 0.722 ± 0.323
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.722TrpTyr: 0.722 ± 0.323
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.772TyrAla: 5.772 ± 1.742
0.722TyrCys: 0.722 ± 0.323
1.443TyrAsp: 1.443 ± 0.62
1.443TyrGlu: 1.443 ± 0.62
2.165TyrPhe: 2.165 ± 0.563
0.722TyrGly: 0.722 ± 0.323
2.165TyrHis: 2.165 ± 0.968
0.722TyrIle: 0.722 ± 0.323
4.329TyrLys: 4.329 ± 1.936
4.329TyrLeu: 4.329 ± 0.951
0.722TyrMet: 0.722 ± 0.323
2.165TyrAsn: 2.165 ± 0.968
0.722TyrPro: 0.722 ± 0.323
2.886TyrGln: 2.886 ± 0.87
3.608TyrArg: 3.608 ± 0.846
2.886TyrSer: 2.886 ± 0.676
4.329TyrThr: 4.329 ± 1.936
2.165TyrVal: 2.165 ± 0.968
0.0TyrTrp: 0.0 ± 0.0
1.443TyrTyr: 1.443 ± 1.2
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1387 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski