Amino acid dipepetide frequency for Stemphylium lycopersici mycovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.686AlaAla: 13.686 ± 3.142
0.955AlaCys: 0.955 ± 0.412
9.23AlaAsp: 9.23 ± 1.138
8.912AlaGlu: 8.912 ± 1.823
6.047AlaPhe: 6.047 ± 0.392
10.185AlaGly: 10.185 ± 1.465
1.273AlaHis: 1.273 ± 0.619
3.501AlaIle: 3.501 ± 0.867
3.183AlaLys: 3.183 ± 1.025
8.593AlaLeu: 8.593 ± 1.555
1.91AlaMet: 1.91 ± 0.579
2.228AlaAsn: 2.228 ± 1.039
6.047AlaPro: 6.047 ± 1.742
2.546AlaGln: 2.546 ± 0.541
8.593AlaArg: 8.593 ± 2.051
6.684AlaSer: 6.684 ± 1.084
4.774AlaThr: 4.774 ± 1.494
8.593AlaVal: 8.593 ± 0.506
4.137AlaTrp: 4.137 ± 1.206
4.774AlaTyr: 4.774 ± 1.462
0.0AlaXaa: 0.0 ± 0.0
Cys
1.591CysAla: 1.591 ± 0.672
0.0CysCys: 0.0 ± 0.0
0.955CysAsp: 0.955 ± 0.759
0.318CysGlu: 0.318 ± 0.285
0.318CysPhe: 0.318 ± 0.273
2.864CysGly: 2.864 ± 1.313
0.318CysHis: 0.318 ± 0.243
0.0CysIle: 0.0 ± 0.0
0.318CysLys: 0.318 ± 0.285
0.955CysLeu: 0.955 ± 0.187
0.318CysMet: 0.318 ± 0.273
0.0CysAsn: 0.0 ± 0.0
0.637CysPro: 0.637 ± 0.485
0.0CysGln: 0.0 ± 0.0
0.955CysArg: 0.955 ± 0.35
1.591CysSer: 1.591 ± 0.672
0.318CysThr: 0.318 ± 0.243
1.591CysVal: 1.591 ± 0.53
0.0CysTrp: 0.0 ± 0.0
0.318CysTyr: 0.318 ± 0.413
0.0CysXaa: 0.0 ± 0.0
Asp
8.912AspAla: 8.912 ± 1.865
0.955AspCys: 0.955 ± 0.759
4.774AspAsp: 4.774 ± 1.294
2.546AspGlu: 2.546 ± 0.678
3.501AspPhe: 3.501 ± 0.811
8.275AspGly: 8.275 ± 2.243
1.91AspHis: 1.91 ± 0.294
1.591AspIle: 1.591 ± 0.416
0.955AspLys: 0.955 ± 0.412
6.684AspLeu: 6.684 ± 1.128
1.273AspMet: 1.273 ± 0.377
0.0AspAsn: 0.0 ± 0.0
2.864AspPro: 2.864 ± 1.435
2.228AspGln: 2.228 ± 1.03
5.729AspArg: 5.729 ± 0.825
0.955AspSer: 0.955 ± 0.187
1.591AspThr: 1.591 ± 0.658
9.23AspVal: 9.23 ± 1.751
1.273AspTrp: 1.273 ± 0.549
2.864AspTyr: 2.864 ± 0.228
0.0AspXaa: 0.0 ± 0.0
Glu
4.456GluAla: 4.456 ± 1.518
0.637GluCys: 0.637 ± 0.321
2.546GluAsp: 2.546 ± 0.509
4.137GluGlu: 4.137 ± 1.221
0.318GluPhe: 0.318 ± 0.243
4.456GluGly: 4.456 ± 0.581
1.273GluHis: 1.273 ± 0.291
1.591GluIle: 1.591 ± 0.53
2.864GluLys: 2.864 ± 1.14
4.774GluLeu: 4.774 ± 1.299
1.91GluMet: 1.91 ± 0.375
0.318GluAsn: 0.318 ± 0.243
1.91GluPro: 1.91 ± 0.454
0.0GluGln: 0.0 ± 0.0
6.047GluArg: 6.047 ± 1.07
2.228GluSer: 2.228 ± 0.789
1.91GluThr: 1.91 ± 0.294
7.638GluVal: 7.638 ± 1.239
0.955GluTrp: 0.955 ± 0.187
1.591GluTyr: 1.591 ± 1.213
0.0GluXaa: 0.0 ± 0.0
Phe
2.864PheAla: 2.864 ± 1.462
0.955PheCys: 0.955 ± 0.387
2.546PheAsp: 2.546 ± 0.992
1.91PheGlu: 1.91 ± 0.638
1.591PhePhe: 1.591 ± 0.455
3.819PheGly: 3.819 ± 1.006
1.591PheHis: 1.591 ± 1.032
0.318PheIle: 0.318 ± 0.413
1.591PheLys: 1.591 ± 0.853
3.501PheLeu: 3.501 ± 0.321
0.318PheMet: 0.318 ± 0.285
0.318PheAsn: 0.318 ± 0.413
3.501PhePro: 3.501 ± 1.836
0.955PheGln: 0.955 ± 0.412
2.864PheArg: 2.864 ± 0.281
3.183PheSer: 3.183 ± 0.535
1.591PheThr: 1.591 ± 0.386
2.864PheVal: 2.864 ± 0.865
0.955PheTrp: 0.955 ± 0.412
0.318PheTyr: 0.318 ± 0.243
0.0PheXaa: 0.0 ± 0.0
Gly
10.503GlyAla: 10.503 ± 1.192
1.91GlyCys: 1.91 ± 0.638
7.638GlyAsp: 7.638 ± 1.148
5.729GlyGlu: 5.729 ± 0.691
5.092GlyPhe: 5.092 ± 0.81
15.913GlyGly: 15.913 ± 3.467
1.273GlyHis: 1.273 ± 0.625
1.91GlyIle: 1.91 ± 0.228
3.183GlyLys: 3.183 ± 1.449
8.912GlyLeu: 8.912 ± 2.624
2.228GlyMet: 2.228 ± 0.285
3.183GlyAsn: 3.183 ± 1.294
4.456GlyPro: 4.456 ± 1.326
2.546GlyGln: 2.546 ± 0.516
7.002GlyArg: 7.002 ± 0.848
7.957GlySer: 7.957 ± 1.437
4.137GlyThr: 4.137 ± 0.829
10.185GlyVal: 10.185 ± 1.422
3.819GlyTrp: 3.819 ± 0.75
2.864GlyTyr: 2.864 ± 1.012
0.0GlyXaa: 0.0 ± 0.0
His
1.91HisAla: 1.91 ± 0.601
0.0HisCys: 0.0 ± 0.0
1.273HisAsp: 1.273 ± 0.391
0.955HisGlu: 0.955 ± 0.543
0.955HisPhe: 0.955 ± 0.473
1.591HisGly: 1.591 ± 0.386
0.637HisHis: 0.637 ± 0.258
0.318HisIle: 0.318 ± 0.285
1.273HisLys: 1.273 ± 0.97
1.91HisLeu: 1.91 ± 0.579
0.637HisMet: 0.637 ± 0.435
0.318HisAsn: 0.318 ± 0.413
1.591HisPro: 1.591 ± 0.647
0.637HisGln: 0.637 ± 0.258
1.591HisArg: 1.591 ± 0.502
0.318HisSer: 0.318 ± 0.243
0.318HisThr: 0.318 ± 0.285
2.546HisVal: 2.546 ± 0.511
0.637HisTrp: 0.637 ± 0.258
0.318HisTyr: 0.318 ± 0.243
0.0HisXaa: 0.0 ± 0.0
Ile
1.91IleAla: 1.91 ± 0.353
0.0IleCys: 0.0 ± 0.0
1.91IleAsp: 1.91 ± 0.638
1.273IleGlu: 1.273 ± 0.291
0.318IlePhe: 0.318 ± 0.243
3.183IleGly: 3.183 ± 0.705
0.318IleHis: 0.318 ± 0.243
0.955IleIle: 0.955 ± 0.412
0.637IleLys: 0.637 ± 0.485
2.228IleLeu: 2.228 ± 0.563
1.273IleMet: 1.273 ± 0.738
0.0IleAsn: 0.0 ± 0.0
2.546IlePro: 2.546 ± 0.96
0.318IleGln: 0.318 ± 0.243
0.955IleArg: 0.955 ± 0.728
0.637IleSer: 0.637 ± 0.383
1.273IleThr: 1.273 ± 0.625
1.91IleVal: 1.91 ± 0.454
0.0IleTrp: 0.0 ± 0.0
0.318IleTyr: 0.318 ± 0.243
0.0IleXaa: 0.0 ± 0.0
Lys
3.501LysAla: 3.501 ± 1.133
0.318LysCys: 0.318 ± 0.243
1.591LysAsp: 1.591 ± 0.467
1.273LysGlu: 1.273 ± 0.97
1.91LysPhe: 1.91 ± 0.823
2.864LysGly: 2.864 ± 1.448
0.318LysHis: 0.318 ± 0.285
0.318LysIle: 0.318 ± 0.285
1.591LysLys: 1.591 ± 0.853
2.228LysLeu: 2.228 ± 0.596
0.0LysMet: 0.0 ± 0.0
0.318LysAsn: 0.318 ± 0.243
0.637LysPro: 0.637 ± 0.258
0.318LysGln: 0.318 ± 0.243
2.864LysArg: 2.864 ± 1.805
1.591LysSer: 1.591 ± 0.791
0.637LysThr: 0.637 ± 0.57
1.91LysVal: 1.91 ± 0.294
0.637LysTrp: 0.637 ± 0.283
1.273LysTyr: 1.273 ± 0.391
0.0LysXaa: 0.0 ± 0.0
Leu
11.139LeuAla: 11.139 ± 2.27
1.591LeuCys: 1.591 ± 0.455
5.729LeuAsp: 5.729 ± 0.609
5.411LeuGlu: 5.411 ± 0.683
1.591LeuPhe: 1.591 ± 0.672
9.866LeuGly: 9.866 ± 1.707
1.273LeuHis: 1.273 ± 0.625
1.91LeuIle: 1.91 ± 0.848
3.183LeuLys: 3.183 ± 0.954
13.367LeuLeu: 13.367 ± 1.349
2.228LeuMet: 2.228 ± 0.65
2.864LeuAsn: 2.864 ± 0.846
4.137LeuPro: 4.137 ± 0.867
2.546LeuGln: 2.546 ± 0.405
9.23LeuArg: 9.23 ± 0.686
7.957LeuSer: 7.957 ± 1.149
3.819LeuThr: 3.819 ± 0.852
5.092LeuVal: 5.092 ± 0.921
2.864LeuTrp: 2.864 ± 0.865
2.228LeuTyr: 2.228 ± 0.985
0.0LeuXaa: 0.0 ± 0.0
Met
2.864MetAla: 2.864 ± 0.737
0.0MetCys: 0.0 ± 0.0
0.955MetAsp: 0.955 ± 0.491
0.955MetGlu: 0.955 ± 0.187
0.637MetPhe: 0.637 ± 0.383
1.591MetGly: 1.591 ± 0.725
0.0MetHis: 0.0 ± 0.0
0.318MetIle: 0.318 ± 0.285
0.318MetLys: 0.318 ± 0.243
2.228MetLeu: 2.228 ± 0.703
0.0MetMet: 0.0 ± 0.0
0.318MetAsn: 0.318 ± 0.243
2.228MetPro: 2.228 ± 0.53
0.318MetGln: 0.318 ± 0.285
2.228MetArg: 2.228 ± 0.572
1.91MetSer: 1.91 ± 0.774
0.637MetThr: 0.637 ± 0.283
1.91MetVal: 1.91 ± 0.375
0.0MetTrp: 0.0 ± 0.0
0.637MetTyr: 0.637 ± 0.258
0.0MetXaa: 0.0 ± 0.0
Asn
3.501AsnAla: 3.501 ± 0.416
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.273AsnGlu: 1.273 ± 0.291
1.273AsnPhe: 1.273 ± 0.291
1.273AsnGly: 1.273 ± 0.391
0.318AsnHis: 0.318 ± 0.273
0.318AsnIle: 0.318 ± 0.413
0.318AsnLys: 0.318 ± 0.243
1.273AsnLeu: 1.273 ± 0.391
0.318AsnMet: 0.318 ± 0.243
0.0AsnAsn: 0.0 ± 0.0
0.955AsnPro: 0.955 ± 0.543
0.318AsnGln: 0.318 ± 0.243
1.591AsnArg: 1.591 ± 0.359
0.637AsnSer: 0.637 ± 0.283
0.637AsnThr: 0.637 ± 0.258
1.591AsnVal: 1.591 ± 0.824
0.955AsnTrp: 0.955 ± 0.35
0.955AsnTyr: 0.955 ± 0.5
0.0AsnXaa: 0.0 ± 0.0
Pro
7.957ProAla: 7.957 ± 3.058
1.273ProCys: 1.273 ± 0.721
3.501ProAsp: 3.501 ± 0.822
1.91ProGlu: 1.91 ± 0.472
1.273ProPhe: 1.273 ± 0.619
7.32ProGly: 7.32 ± 1.709
0.955ProHis: 0.955 ± 0.524
0.637ProIle: 0.637 ± 0.258
1.591ProLys: 1.591 ± 0.416
3.183ProLeu: 3.183 ± 0.429
0.637ProMet: 0.637 ± 0.485
0.0ProAsn: 0.0 ± 0.0
5.411ProPro: 5.411 ± 1.575
1.273ProGln: 1.273 ± 0.27
3.183ProArg: 3.183 ± 0.769
2.546ProSer: 2.546 ± 0.509
1.273ProThr: 1.273 ± 0.391
6.047ProVal: 6.047 ± 1.257
0.955ProTrp: 0.955 ± 0.412
1.273ProTyr: 1.273 ± 0.771
0.0ProXaa: 0.0 ± 0.0
Gln
3.183GlnAla: 3.183 ± 0.674
0.0GlnCys: 0.0 ± 0.0
1.591GlnAsp: 1.591 ± 0.455
0.637GlnGlu: 0.637 ± 0.57
0.637GlnPhe: 0.637 ± 0.485
3.501GlnGly: 3.501 ± 0.921
0.637GlnHis: 0.637 ± 0.283
0.0GlnIle: 0.0 ± 0.0
0.318GlnLys: 0.318 ± 0.243
2.546GlnLeu: 2.546 ± 0.516
0.0GlnMet: 0.0 ± 0.0
0.318GlnAsn: 0.318 ± 0.285
0.318GlnPro: 0.318 ± 0.285
0.637GlnGln: 0.637 ± 0.485
1.591GlnArg: 1.591 ± 0.467
2.228GlnSer: 2.228 ± 0.343
0.318GlnThr: 0.318 ± 0.413
2.864GlnVal: 2.864 ± 1.847
0.318GlnTrp: 0.318 ± 0.243
0.318GlnTyr: 0.318 ± 0.285
0.0GlnXaa: 0.0 ± 0.0
Arg
12.094ArgAla: 12.094 ± 2.244
0.0ArgCys: 0.0 ± 0.0
7.957ArgAsp: 7.957 ± 1.997
4.137ArgGlu: 4.137 ± 0.897
1.591ArgPhe: 1.591 ± 0.416
9.23ArgGly: 9.23 ± 1.314
3.183ArgHis: 3.183 ± 0.721
2.546ArgIle: 2.546 ± 0.702
1.273ArgLys: 1.273 ± 0.666
8.912ArgLeu: 8.912 ± 1.149
1.591ArgMet: 1.591 ± 0.2
2.228ArgAsn: 2.228 ± 0.251
3.501ArgPro: 3.501 ± 0.438
1.91ArgGln: 1.91 ± 0.512
6.684ArgArg: 6.684 ± 1.962
4.137ArgSer: 4.137 ± 1.333
3.183ArgThr: 3.183 ± 0.771
6.684ArgVal: 6.684 ± 1.462
1.591ArgTrp: 1.591 ± 0.538
3.183ArgTyr: 3.183 ± 1.332
0.0ArgXaa: 0.0 ± 0.0
Ser
6.684SerAla: 6.684 ± 0.824
1.591SerCys: 1.591 ± 1.22
3.501SerAsp: 3.501 ± 0.547
2.864SerGlu: 2.864 ± 0.784
2.864SerPhe: 2.864 ± 0.662
6.047SerGly: 6.047 ± 1.127
1.91SerHis: 1.91 ± 0.823
1.591SerIle: 1.591 ± 0.676
0.955SerLys: 0.955 ± 0.412
5.729SerLeu: 5.729 ± 1.452
1.273SerMet: 1.273 ± 0.378
1.591SerAsn: 1.591 ± 0.386
3.183SerPro: 3.183 ± 0.712
0.0SerGln: 0.0 ± 0.0
5.411SerArg: 5.411 ± 1.007
4.137SerSer: 4.137 ± 0.869
3.501SerThr: 3.501 ± 1.106
6.047SerVal: 6.047 ± 2.157
1.591SerTrp: 1.591 ± 0.359
0.637SerTyr: 0.637 ± 0.485
0.0SerXaa: 0.0 ± 0.0
Thr
5.092ThrAla: 5.092 ± 1.477
0.637ThrCys: 0.637 ± 0.283
2.546ThrAsp: 2.546 ± 1.607
1.591ThrGlu: 1.591 ± 0.386
1.591ThrPhe: 1.591 ± 0.896
3.183ThrGly: 3.183 ± 1.049
0.318ThrHis: 0.318 ± 0.273
0.955ThrIle: 0.955 ± 0.491
0.318ThrLys: 0.318 ± 0.273
4.456ThrLeu: 4.456 ± 0.474
0.318ThrMet: 0.318 ± 0.285
0.318ThrAsn: 0.318 ± 0.243
1.591ThrPro: 1.591 ± 0.398
0.955ThrGln: 0.955 ± 0.855
3.819ThrArg: 3.819 ± 0.873
2.546ThrSer: 2.546 ± 0.864
1.273ThrThr: 1.273 ± 0.619
3.183ThrVal: 3.183 ± 0.797
0.637ThrTrp: 0.637 ± 0.258
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
9.548ValAla: 9.548 ± 0.826
1.273ValCys: 1.273 ± 0.378
6.047ValAsp: 6.047 ± 0.462
3.819ValGlu: 3.819 ± 1.077
3.819ValPhe: 3.819 ± 1.753
7.957ValGly: 7.957 ± 0.921
0.637ValHis: 0.637 ± 0.321
2.546ValIle: 2.546 ± 0.511
1.591ValLys: 1.591 ± 0.59
10.503ValLeu: 10.503 ± 1.466
2.546ValMet: 2.546 ± 0.873
2.546ValAsn: 2.546 ± 0.751
5.092ValPro: 5.092 ± 0.9
3.183ValGln: 3.183 ± 0.521
9.548ValArg: 9.548 ± 1.711
6.047ValSer: 6.047 ± 2.343
1.591ValThr: 1.591 ± 0.359
7.957ValVal: 7.957 ± 1.791
1.91ValTrp: 1.91 ± 0.774
3.183ValTyr: 3.183 ± 0.771
0.0ValXaa: 0.0 ± 0.0
Trp
1.273TrpAla: 1.273 ± 0.771
0.637TrpCys: 0.637 ± 0.383
2.228TrpAsp: 2.228 ± 0.53
0.955TrpGlu: 0.955 ± 0.486
0.637TrpPhe: 0.637 ± 0.826
4.774TrpGly: 4.774 ± 1.528
0.637TrpHis: 0.637 ± 0.258
0.318TrpIle: 0.318 ± 0.413
0.318TrpLys: 0.318 ± 0.273
2.864TrpLeu: 2.864 ± 0.865
0.955TrpMet: 0.955 ± 0.728
0.637TrpAsn: 0.637 ± 0.321
1.273TrpPro: 1.273 ± 0.754
0.955TrpGln: 0.955 ± 0.728
1.91TrpArg: 1.91 ± 0.472
1.273TrpSer: 1.273 ± 0.291
0.318TrpThr: 0.318 ± 0.273
1.273TrpVal: 1.273 ± 0.291
0.637TrpTrp: 0.637 ± 0.283
0.318TrpTyr: 0.318 ± 0.243
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.183TyrAla: 3.183 ± 0.784
0.637TyrCys: 0.637 ± 0.321
1.91TyrAsp: 1.91 ± 0.472
0.955TyrGlu: 0.955 ± 0.5
1.591TyrPhe: 1.591 ± 0.416
2.546TyrGly: 2.546 ± 0.775
0.955TyrHis: 0.955 ± 0.451
0.318TyrIle: 0.318 ± 0.273
0.318TyrLys: 0.318 ± 0.243
3.183TyrLeu: 3.183 ± 0.751
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.318TyrPro: 0.318 ± 0.243
0.318TyrGln: 0.318 ± 0.273
3.819TyrArg: 3.819 ± 0.873
2.546TyrSer: 2.546 ± 0.06
2.228TyrThr: 2.228 ± 0.596
2.228TyrVal: 2.228 ± 0.604
0.318TyrTrp: 0.318 ± 0.243
0.637TyrTyr: 0.637 ± 0.485
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3143 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski