Amino acid dipepetide frequency for Altererythrobacter xixiisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.148AlaAla: 18.148 ± 0.189	1.075AlaCys: 1.075 ± 0.033	8.371AlaAsp: 8.371 ± 0.412	7.796AlaGlu: 7.796 ± 0.103	4.022AlaPhe: 4.022 ± 0.065	11.642AlaGly: 11.642 ± 0.125	2.171AlaHis: 2.171 ± 0.045	6.584AlaIle: 6.584 ± 0.086	3.131AlaLys: 3.131 ± 0.062	13.605AlaLeu: 13.605 ± 0.135	3.772AlaMet: 3.772 ± 0.064	3.322AlaAsn: 3.322 ± 0.069	6.312AlaPro: 6.312 ± 0.087	5.064AlaGln: 5.064 ± 0.083	9.349AlaArg: 9.349 ± 0.111	6.59AlaSer: 6.59 ± 0.073	6.121AlaThr: 6.121 ± 0.086	8.63AlaVal: 8.63 ± 0.094	1.665AlaTrp: 1.665 ± 0.042	2.434AlaTyr: 2.434 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.003CysAla: 1.003 ± 0.028	0.097CysCys: 0.097 ± 0.01	0.544CysAsp: 0.544 ± 0.023	0.393CysGlu: 0.393 ± 0.017	0.296CysPhe: 0.296 ± 0.016	0.855CysGly: 0.855 ± 0.032	0.228CysHis: 0.228 ± 0.015	0.341CysIle: 0.341 ± 0.017	0.145CysLys: 0.145 ± 0.013	0.721CysLeu: 0.721 ± 0.025	0.163CysMet: 0.163 ± 0.011	0.22CysAsn: 0.22 ± 0.013	0.421CysPro: 0.421 ± 0.019	0.232CysGln: 0.232 ± 0.013	0.573CysArg: 0.573 ± 0.024	0.515CysSer: 0.515 ± 0.023	0.395CysThr: 0.395 ± 0.019	0.565CysVal: 0.565 ± 0.023	0.106CysTrp: 0.106 ± 0.01	0.183CysTyr: 0.183 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.12AspAla: 8.12 ± 0.403	0.462AspCys: 0.462 ± 0.022	3.61AspAsp: 3.61 ± 0.071	3.123AspGlu: 3.123 ± 0.06	2.27AspPhe: 2.27 ± 0.042	5.929AspGly: 5.929 ± 0.088	1.403AspHis: 1.403 ± 0.041	3.125AspIle: 3.125 ± 0.056	1.516AspLys: 1.516 ± 0.037	5.92AspLeu: 5.92 ± 0.077	1.441AspMet: 1.441 ± 0.037	1.628AspAsn: 1.628 ± 0.045	3.782AspPro: 3.782 ± 0.057	2.149AspGln: 2.149 ± 0.038	4.989AspArg: 4.989 ± 0.071	2.592AspSer: 2.592 ± 0.045	2.612AspThr: 2.612 ± 0.045	4.142AspVal: 4.142 ± 0.056	1.139AspTrp: 1.139 ± 0.031	1.659AspTyr: 1.659 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	6.942GluAla: 6.942 ± 0.098	0.332GluCys: 0.332 ± 0.019	2.875GluAsp: 2.875 ± 0.061	3.142GluGlu: 3.142 ± 0.063	1.766GluPhe: 1.766 ± 0.04	4.306GluGly: 4.306 ± 0.062	1.074GluHis: 1.074 ± 0.03	2.844GluIle: 2.844 ± 0.049	1.711GluLys: 1.711 ± 0.043	5.268GluLeu: 5.268 ± 0.066	1.419GluMet: 1.419 ± 0.037	1.499GluAsn: 1.499 ± 0.036	2.522GluPro: 2.522 ± 0.045	2.499GluGln: 2.499 ± 0.045	4.601GluArg: 4.601 ± 0.074	2.306GluSer: 2.306 ± 0.046	2.949GluThr: 2.949 ± 0.051	3.446GluVal: 3.446 ± 0.059	0.888GluTrp: 0.888 ± 0.03	1.099GluTyr: 1.099 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.848PheAla: 4.848 ± 0.064	0.326PheCys: 0.326 ± 0.016	2.796PheAsp: 2.796 ± 0.051	1.864PheGlu: 1.864 ± 0.038	1.239PhePhe: 1.239 ± 0.036	3.75PheGly: 3.75 ± 0.052	0.766PheHis: 0.766 ± 0.026	1.604PheIle: 1.604 ± 0.04	0.717PheLys: 0.717 ± 0.027	3.051PheLeu: 3.051 ± 0.056	0.76PheMet: 0.76 ± 0.032	1.099PheAsn: 1.099 ± 0.033	1.562PhePro: 1.562 ± 0.034	0.951PheGln: 0.951 ± 0.03	2.287PheArg: 2.287 ± 0.045	2.216PheSer: 2.216 ± 0.044	2.161PheThr: 2.161 ± 0.044	2.566PheVal: 2.566 ± 0.05	0.518PheTrp: 0.518 ± 0.023	0.885PheTyr: 0.885 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.76GlyAla: 9.76 ± 0.114	0.852GlyCys: 0.852 ± 0.03	5.104GlyAsp: 5.104 ± 0.064	4.794GlyGlu: 4.794 ± 0.065	3.624GlyPhe: 3.624 ± 0.062	8.077GlyGly: 8.077 ± 0.134	1.854GlyHis: 1.854 ± 0.041	4.418GlyIle: 4.418 ± 0.067	2.904GlyLys: 2.904 ± 0.057	8.668GlyLeu: 8.668 ± 0.088	2.528GlyMet: 2.528 ± 0.05	2.672GlyAsn: 2.672 ± 0.057	3.664GlyPro: 3.664 ± 0.062	3.478GlyGln: 3.478 ± 0.055	6.33GlyArg: 6.33 ± 0.089	5.164GlySer: 5.164 ± 0.08	5.037GlyThr: 5.037 ± 0.094	6.161GlyVal: 6.161 ± 0.084	1.68GlyTrp: 1.68 ± 0.046	2.331GlyTyr: 2.331 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.349HisAla: 2.349 ± 0.046	0.244HisCys: 0.244 ± 0.014	1.341HisAsp: 1.341 ± 0.03	0.946HisGlu: 0.946 ± 0.029	0.839HisPhe: 0.839 ± 0.028	1.962HisGly: 1.962 ± 0.054	0.538HisHis: 0.538 ± 0.026	0.872HisIle: 0.872 ± 0.028	0.396HisLys: 0.396 ± 0.021	1.814HisLeu: 1.814 ± 0.038	0.465HisMet: 0.465 ± 0.019	0.481HisAsn: 0.481 ± 0.018	1.299HisPro: 1.299 ± 0.04	0.611HisGln: 0.611 ± 0.025	1.441HisArg: 1.441 ± 0.037	0.99HisSer: 0.99 ± 0.025	0.775HisThr: 0.775 ± 0.028	1.366HisVal: 1.366 ± 0.039	0.361HisTrp: 0.361 ± 0.019	0.569HisTyr: 0.569 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	7.722IleAla: 7.722 ± 0.082	0.481IleCys: 0.481 ± 0.02	3.892IleAsp: 3.892 ± 0.071	3.294IleGlu: 3.294 ± 0.051	1.578IlePhe: 1.578 ± 0.038	5.181IleGly: 5.181 ± 0.067	0.899IleHis: 0.899 ± 0.028	2.303IleIle: 2.303 ± 0.046	1.068IleLys: 1.068 ± 0.032	3.699IleLeu: 3.699 ± 0.052	0.946IleMet: 0.946 ± 0.029	1.502IleAsn: 1.502 ± 0.036	2.399IlePro: 2.399 ± 0.051	1.198IleGln: 1.198 ± 0.035	3.349IleArg: 3.349 ± 0.058	2.84IleSer: 2.84 ± 0.055	2.959IleThr: 2.959 ± 0.053	3.677IleVal: 3.677 ± 0.054	0.616IleTrp: 0.616 ± 0.023	1.078IleTyr: 1.078 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.114LysAla: 3.114 ± 0.062	0.13LysCys: 0.13 ± 0.01	1.361LysAsp: 1.361 ± 0.035	1.078LysGlu: 1.078 ± 0.035	0.752LysPhe: 0.752 ± 0.027	2.117LysGly: 2.117 ± 0.045	0.464LysHis: 0.464 ± 0.022	1.364LysIle: 1.364 ± 0.042	0.796LysLys: 0.796 ± 0.039	2.666LysLeu: 2.666 ± 0.055	0.614LysMet: 0.614 ± 0.025	0.662LysAsn: 0.662 ± 0.025	1.635LysPro: 1.635 ± 0.045	0.888LysGln: 0.888 ± 0.03	1.902LysArg: 1.902 ± 0.044	1.362LysSer: 1.362 ± 0.042	1.358LysThr: 1.358 ± 0.038	1.742LysVal: 1.742 ± 0.044	0.348LysTrp: 0.348 ± 0.016	0.535LysTyr: 0.535 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.364LeuAla: 14.364 ± 0.158	0.795LeuCys: 0.795 ± 0.025	5.832LeuAsp: 5.832 ± 0.078	4.81LeuGlu: 4.81 ± 0.069	3.654LeuPhe: 3.654 ± 0.067	8.121LeuGly: 8.121 ± 0.096	1.821LeuHis: 1.821 ± 0.051	4.907LeuIle: 4.907 ± 0.067	2.47LeuLys: 2.47 ± 0.051	9.958LeuLeu: 9.958 ± 0.125	2.284LeuMet: 2.284 ± 0.056	2.53LeuAsn: 2.53 ± 0.049	5.77LeuPro: 5.77 ± 0.088	3.166LeuGln: 3.166 ± 0.055	7.136LeuArg: 7.136 ± 0.092	6.098LeuSer: 6.098 ± 0.069	5.815LeuThr: 5.815 ± 0.08	6.866LeuVal: 6.866 ± 0.077	1.244LeuTrp: 1.244 ± 0.037	1.921LeuTyr: 1.921 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	3.318MetAla: 3.318 ± 0.056	0.156MetCys: 0.156 ± 0.012	1.233MetAsp: 1.233 ± 0.029	1.105MetGlu: 1.105 ± 0.035	0.703MetPhe: 0.703 ± 0.029	1.944MetGly: 1.944 ± 0.048	0.453MetHis: 0.453 ± 0.022	1.38MetIle: 1.38 ± 0.037	0.772MetLys: 0.772 ± 0.028	2.732MetLeu: 2.732 ± 0.058	0.668MetMet: 0.668 ± 0.025	0.749MetAsn: 0.749 ± 0.025	1.524MetPro: 1.524 ± 0.035	0.89MetGln: 0.89 ± 0.035	1.877MetArg: 1.877 ± 0.041	1.372MetSer: 1.372 ± 0.032	1.6MetThr: 1.6 ± 0.035	1.688MetVal: 1.688 ± 0.04	0.231MetTrp: 0.231 ± 0.013	0.292MetTyr: 0.292 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.372AsnAla: 3.372 ± 0.069	0.247AsnCys: 0.247 ± 0.018	1.516AsnAsp: 1.516 ± 0.039	1.155AsnGlu: 1.155 ± 0.033	1.128AsnPhe: 1.128 ± 0.037	2.723AsnGly: 2.723 ± 0.058	0.54AsnHis: 0.54 ± 0.024	1.385AsnIle: 1.385 ± 0.039	0.56AsnLys: 0.56 ± 0.024	2.661AsnLeu: 2.661 ± 0.049	0.604AsnMet: 0.604 ± 0.022	0.886AsnAsn: 0.886 ± 0.034	1.927AsnPro: 1.927 ± 0.048	0.911AsnGln: 0.911 ± 0.028	2.06AsnArg: 2.06 ± 0.043	1.51AsnSer: 1.51 ± 0.039	1.337AsnThr: 1.337 ± 0.043	1.936AsnVal: 1.936 ± 0.043	0.483AsnTrp: 0.483 ± 0.019	0.728AsnTyr: 0.728 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	7.625ProAla: 7.625 ± 0.106	0.33ProCys: 0.33 ± 0.018	3.921ProAsp: 3.921 ± 0.058	3.487ProGlu: 3.487 ± 0.06	1.937ProPhe: 1.937 ± 0.042	4.823ProGly: 4.823 ± 0.066	1.054ProHis: 1.054 ± 0.034	2.471ProIle: 2.471 ± 0.05	1.124ProLys: 1.124 ± 0.033	5.038ProLeu: 5.038 ± 0.074	1.228ProMet: 1.228 ± 0.038	1.277ProAsn: 1.277 ± 0.036	2.982ProPro: 2.982 ± 0.085	2.019ProGln: 2.019 ± 0.038	3.071ProArg: 3.071 ± 0.064	2.679ProSer: 2.679 ± 0.047	2.582ProThr: 2.582 ± 0.055	4.288ProVal: 4.288 ± 0.065	0.678ProTrp: 0.678 ± 0.027	1.078ProTyr: 1.078 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	4.946GlnAla: 4.946 ± 0.086	0.244GlnCys: 0.244 ± 0.016	1.858GlnAsp: 1.858 ± 0.04	1.582GlnGlu: 1.582 ± 0.033	1.264GlnPhe: 1.264 ± 0.037	2.856GlnGly: 2.856 ± 0.043	0.737GlnHis: 0.737 ± 0.026	1.999GlnIle: 1.999 ± 0.043	0.756GlnLys: 0.756 ± 0.025	3.82GlnLeu: 3.82 ± 0.067	0.908GlnMet: 0.908 ± 0.028	0.896GlnAsn: 0.896 ± 0.023	2.213GlnPro: 2.213 ± 0.046	1.65GlnGln: 1.65 ± 0.041	2.803GlnArg: 2.803 ± 0.057	1.9GlnSer: 1.9 ± 0.046	1.847GlnThr: 1.847 ± 0.043	2.462GlnVal: 2.462 ± 0.049	0.53GlnTrp: 0.53 ± 0.022	0.663GlnTyr: 0.663 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	8.426ArgAla: 8.426 ± 0.094	0.515ArgCys: 0.515 ± 0.022	4.449ArgAsp: 4.449 ± 0.064	3.973ArgGlu: 3.973 ± 0.058	3.135ArgPhe: 3.135 ± 0.058	5.063ArgGly: 5.063 ± 0.067	1.676ArgHis: 1.676 ± 0.038	4.099ArgIle: 4.099 ± 0.058	1.948ArgLys: 1.948 ± 0.05	7.973ArgLeu: 7.973 ± 0.101	1.975ArgMet: 1.975 ± 0.041	2.11ArgAsn: 2.11 ± 0.052	3.59ArgPro: 3.59 ± 0.064	2.96ArgGln: 2.96 ± 0.059	5.693ArgArg: 5.693 ± 0.09	3.872ArgSer: 3.872 ± 0.052	3.343ArgThr: 3.343 ± 0.057	4.744ArgVal: 4.744 ± 0.06	1.205ArgTrp: 1.205 ± 0.035	1.826ArgTyr: 1.826 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.662SerAla: 6.662 ± 0.099	0.441SerCys: 0.441 ± 0.018	3.243SerAsp: 3.243 ± 0.062	2.501SerGlu: 2.501 ± 0.047	2.433SerPhe: 2.433 ± 0.046	5.703SerGly: 5.703 ± 0.071	0.985SerHis: 0.985 ± 0.03	2.623SerIle: 2.623 ± 0.048	1.18SerLys: 1.18 ± 0.033	5.275SerLeu: 5.275 ± 0.082	1.276SerMet: 1.276 ± 0.038	1.518SerAsn: 1.518 ± 0.04	2.934SerPro: 2.934 ± 0.051	1.753SerGln: 1.753 ± 0.039	3.632SerArg: 3.632 ± 0.055	2.948SerSer: 2.948 ± 0.055	2.778SerThr: 2.778 ± 0.056	3.75SerVal: 3.75 ± 0.073	0.89SerTrp: 0.89 ± 0.031	1.411SerTyr: 1.411 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.449ThrAla: 6.449 ± 0.095	0.346ThrCys: 0.346 ± 0.018	3.022ThrAsp: 3.022 ± 0.056	2.415ThrGlu: 2.415 ± 0.051	1.641ThrPhe: 1.641 ± 0.038	5.573ThrGly: 5.573 ± 0.09	0.927ThrHis: 0.927 ± 0.028	2.958ThrIle: 2.958 ± 0.062	1.072ThrLys: 1.072 ± 0.033	5.676ThrLeu: 5.676 ± 0.075	1.129ThrMet: 1.129 ± 0.031	1.445ThrAsn: 1.445 ± 0.047	3.564ThrPro: 3.564 ± 0.069	1.717ThrGln: 1.717 ± 0.045	3.588ThrArg: 3.588 ± 0.055	2.836ThrSer: 2.836 ± 0.058	2.776ThrThr: 2.776 ± 0.057	3.846ThrVal: 3.846 ± 0.068	0.538ThrTrp: 0.538 ± 0.021	1.152ThrTyr: 1.152 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	8.68ValAla: 8.68 ± 0.085	0.541ValCys: 0.541 ± 0.024	4.293ValAsp: 4.293 ± 0.059	4.339ValGlu: 4.339 ± 0.072	2.289ValPhe: 2.289 ± 0.051	5.303ValGly: 5.303 ± 0.074	1.235ValHis: 1.235 ± 0.034	3.825ValIle: 3.825 ± 0.059	1.746ValLys: 1.746 ± 0.044	7.076ValLeu: 7.076 ± 0.082	1.729ValMet: 1.729 ± 0.039	1.98ValAsn: 1.98 ± 0.049	3.82ValPro: 3.82 ± 0.06	2.256ValGln: 2.256 ± 0.047	4.589ValArg: 4.589 ± 0.058	4.073ValSer: 4.073 ± 0.062	4.351ValThr: 4.351 ± 0.066	5.216ValVal: 5.216 ± 0.089	0.876ValTrp: 0.876 ± 0.031	1.249ValTyr: 1.249 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.401TrpAla: 1.401 ± 0.036	0.147TrpCys: 0.147 ± 0.012	0.776TrpAsp: 0.776 ± 0.026	0.6TrpGlu: 0.6 ± 0.024	0.551TrpPhe: 0.551 ± 0.02	1.021TrpGly: 1.021 ± 0.031	0.378TrpHis: 0.378 ± 0.017	0.697TrpIle: 0.697 ± 0.025	0.417TrpLys: 0.417 ± 0.017	1.857TrpLeu: 1.857 ± 0.044	0.377TrpMet: 0.377 ± 0.017	0.521TrpAsn: 0.521 ± 0.023	0.706TrpPro: 0.706 ± 0.024	0.785TrpGln: 0.785 ± 0.026	1.375TrpArg: 1.375 ± 0.039	0.833TrpSer: 0.833 ± 0.025	0.763TrpThr: 0.763 ± 0.024	0.872TrpVal: 0.872 ± 0.03	0.237TrpTrp: 0.237 ± 0.015	0.294TrpTyr: 0.294 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.552TyrAla: 2.552 ± 0.036	0.237TyrCys: 0.237 ± 0.014	1.575TyrAsp: 1.575 ± 0.038	1.088TyrGlu: 1.088 ± 0.031	0.845TyrPhe: 0.845 ± 0.025	2.154TyrGly: 2.154 ± 0.051	0.456TyrHis: 0.456 ± 0.019	0.883TyrIle: 0.883 ± 0.031	0.461TyrLys: 0.461 ± 0.02	2.085TyrLeu: 2.085 ± 0.043	0.403TyrMet: 0.403 ± 0.018	0.672TyrAsn: 0.672 ± 0.026	1.063TyrPro: 1.063 ± 0.031	0.756TyrGln: 0.756 ± 0.026	1.931TyrArg: 1.931 ± 0.043	1.244TyrSer: 1.244 ± 0.037	1.107TyrThr: 1.107 ± 0.034	1.501TyrVal: 1.501 ± 0.037	0.375TyrTrp: 0.375 ± 0.019	0.622TyrTyr: 0.622 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3571 proteins (1157999 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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