Amino acid dipepetide frequency for Blautia wexlerae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.794AlaAla: 6.794 ± 0.114	1.065AlaCys: 1.065 ± 0.032	4.813AlaAsp: 4.813 ± 0.072	5.45AlaGlu: 5.45 ± 0.079	2.83AlaPhe: 2.83 ± 0.055	5.819AlaGly: 5.819 ± 0.089	1.094AlaHis: 1.094 ± 0.036	4.717AlaIle: 4.717 ± 0.067	4.797AlaLys: 4.797 ± 0.069	6.293AlaLeu: 6.293 ± 0.07	2.331AlaMet: 2.331 ± 0.044	2.395AlaAsn: 2.395 ± 0.051	1.927AlaPro: 1.927 ± 0.041	2.506AlaGln: 2.506 ± 0.054	2.811AlaArg: 2.811 ± 0.051	3.714AlaSer: 3.714 ± 0.065	3.254AlaThr: 3.254 ± 0.073	6.173AlaVal: 6.173 ± 0.081	0.621AlaTrp: 0.621 ± 0.022	2.706AlaTyr: 2.706 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	1.065CysAla: 1.065 ± 0.035	0.311CysCys: 0.311 ± 0.016	0.854CysAsp: 0.854 ± 0.027	0.968CysGlu: 0.968 ± 0.032	0.661CysPhe: 0.661 ± 0.023	1.536CysGly: 1.536 ± 0.044	0.316CysHis: 0.316 ± 0.015	1.113CysIle: 1.113 ± 0.036	0.924CysLys: 0.924 ± 0.028	1.186CysLeu: 1.186 ± 0.036	0.501CysMet: 0.501 ± 0.023	0.655CysAsn: 0.655 ± 0.025	0.665CysPro: 0.665 ± 0.027	0.474CysGln: 0.474 ± 0.019	0.773CysArg: 0.773 ± 0.028	0.981CysSer: 0.981 ± 0.031	0.824CysThr: 0.824 ± 0.031	1.022CysVal: 1.022 ± 0.029	0.138CysTrp: 0.138 ± 0.01	0.588CysTyr: 0.588 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	4.033AspAla: 4.033 ± 0.065	0.862AspCys: 0.862 ± 0.026	3.114AspAsp: 3.114 ± 0.061	4.73AspGlu: 4.73 ± 0.071	2.705AspPhe: 2.705 ± 0.049	4.484AspGly: 4.484 ± 0.072	0.926AspHis: 0.926 ± 0.029	4.576AspIle: 4.576 ± 0.062	3.857AspLys: 3.857 ± 0.058	4.376AspLeu: 4.376 ± 0.069	1.953AspMet: 1.953 ± 0.045	2.486AspAsn: 2.486 ± 0.056	1.744AspPro: 1.744 ± 0.04	1.474AspGln: 1.474 ± 0.038	2.414AspArg: 2.414 ± 0.05	3.36AspSer: 3.36 ± 0.065	3.416AspThr: 3.416 ± 0.057	3.744AspVal: 3.744 ± 0.064	0.617AspTrp: 0.617 ± 0.026	2.861AspTyr: 2.861 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	5.293GluAla: 5.293 ± 0.069	0.888GluCys: 0.888 ± 0.028	4.364GluAsp: 4.364 ± 0.07	7.078GluGlu: 7.078 ± 0.106	2.728GluPhe: 2.728 ± 0.044	4.242GluGly: 4.242 ± 0.067	1.421GluHis: 1.421 ± 0.036	5.843GluIle: 5.843 ± 0.081	7.249GluLys: 7.249 ± 0.106	6.858GluLeu: 6.858 ± 0.079	2.491GluMet: 2.491 ± 0.047	4.477GluAsn: 4.477 ± 0.063	1.85GluPro: 1.85 ± 0.043	3.09GluGln: 3.09 ± 0.064	3.251GluArg: 3.251 ± 0.068	3.363GluSer: 3.363 ± 0.061	3.8GluThr: 3.8 ± 0.059	4.364GluVal: 4.364 ± 0.06	0.67GluTrp: 0.67 ± 0.029	3.231GluTyr: 3.231 ± 0.063	0.0GluXaa: 0.0 ± 0.0
Phe	2.794PheAla: 2.794 ± 0.056	0.793PheCys: 0.793 ± 0.026	2.458PheAsp: 2.458 ± 0.046	2.54PheGlu: 2.54 ± 0.046	1.779PhePhe: 1.779 ± 0.037	2.941PheGly: 2.941 ± 0.053	0.898PheHis: 0.898 ± 0.027	2.697PheIle: 2.697 ± 0.056	2.036PheLys: 2.036 ± 0.044	3.858PheLeu: 3.858 ± 0.075	1.179PheMet: 1.179 ± 0.03	1.523PheAsn: 1.523 ± 0.038	1.404PhePro: 1.404 ± 0.035	1.354PheGln: 1.354 ± 0.032	1.768PheArg: 1.768 ± 0.043	2.9PheSer: 2.9 ± 0.049	2.331PheThr: 2.331 ± 0.046	2.777PheVal: 2.777 ± 0.045	0.466PheTrp: 0.466 ± 0.022	1.678PheTyr: 1.678 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.654GlyAla: 4.654 ± 0.067	1.318GlyCys: 1.318 ± 0.043	3.465GlyAsp: 3.465 ± 0.057	4.612GlyGlu: 4.612 ± 0.074	2.975GlyPhe: 2.975 ± 0.047	4.62GlyGly: 4.62 ± 0.085	1.236GlyHis: 1.236 ± 0.029	6.104GlyIle: 6.104 ± 0.091	5.742GlyLys: 5.742 ± 0.074	5.495GlyLeu: 5.495 ± 0.084	2.541GlyMet: 2.541 ± 0.056	3.322GlyAsn: 3.322 ± 0.058	1.159GlyPro: 1.159 ± 0.04	2.102GlyGln: 2.102 ± 0.043	2.917GlyArg: 2.917 ± 0.062	3.93GlySer: 3.93 ± 0.07	4.292GlyThr: 4.292 ± 0.06	4.696GlyVal: 4.696 ± 0.064	0.72GlyTrp: 0.72 ± 0.027	3.369GlyTyr: 3.369 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	1.071HisAla: 1.071 ± 0.032	0.308HisCys: 0.308 ± 0.019	0.912HisAsp: 0.912 ± 0.033	1.165HisGlu: 1.165 ± 0.035	0.805HisPhe: 0.805 ± 0.026	1.294HisGly: 1.294 ± 0.035	0.428HisHis: 0.428 ± 0.024	1.421HisIle: 1.421 ± 0.035	1.093HisLys: 1.093 ± 0.027	1.513HisLeu: 1.513 ± 0.032	0.61HisMet: 0.61 ± 0.022	0.748HisAsn: 0.748 ± 0.027	0.857HisPro: 0.857 ± 0.028	0.555HisGln: 0.555 ± 0.021	0.816HisArg: 0.816 ± 0.027	0.999HisSer: 0.999 ± 0.032	1.025HisThr: 1.025 ± 0.027	1.12HisVal: 1.12 ± 0.034	0.172HisTrp: 0.172 ± 0.012	0.775HisTyr: 0.775 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.363IleAla: 5.363 ± 0.078	1.445IleCys: 1.445 ± 0.038	3.941IleAsp: 3.941 ± 0.058	4.624IleGlu: 4.624 ± 0.063	2.974IlePhe: 2.974 ± 0.061	4.807IleGly: 4.807 ± 0.073	1.411IleHis: 1.411 ± 0.034	4.942IleIle: 4.942 ± 0.07	4.192IleLys: 4.192 ± 0.06	7.205IleLeu: 7.205 ± 0.098	2.054IleMet: 2.054 ± 0.043	2.905IleAsn: 2.905 ± 0.05	3.193IlePro: 3.193 ± 0.054	2.497IleGln: 2.497 ± 0.046	3.792IleArg: 3.792 ± 0.06	5.115IleSer: 5.115 ± 0.076	4.24IleThr: 4.24 ± 0.06	4.733IleVal: 4.733 ± 0.075	0.643IleTrp: 0.643 ± 0.025	3.002IleTyr: 3.002 ± 0.053	0.0IleXaa: 0.0 ± 0.0
Lys	5.151LysAla: 5.151 ± 0.074	0.867LysCys: 0.867 ± 0.027	4.198LysAsp: 4.198 ± 0.059	6.869LysGlu: 6.869 ± 0.098	2.102LysPhe: 2.102 ± 0.045	4.246LysGly: 4.246 ± 0.056	1.046LysHis: 1.046 ± 0.031	5.238LysIle: 5.238 ± 0.062	6.795LysLys: 6.795 ± 0.095	5.516LysLeu: 5.516 ± 0.065	2.42LysMet: 2.42 ± 0.046	3.898LysAsn: 3.898 ± 0.061	2.091LysPro: 2.091 ± 0.048	2.567LysGln: 2.567 ± 0.052	3.116LysArg: 3.116 ± 0.059	3.568LysSer: 3.568 ± 0.066	4.224LysThr: 4.224 ± 0.059	4.431LysVal: 4.431 ± 0.07	0.71LysTrp: 0.71 ± 0.022	3.208LysTyr: 3.208 ± 0.052	0.001LysXaa: 0.001 ± 0.001
Leu	6.406LeuAla: 6.406 ± 0.076	1.547LeuCys: 1.547 ± 0.04	5.059LeuAsp: 5.059 ± 0.077	6.19LeuGlu: 6.19 ± 0.083	3.538LeuPhe: 3.538 ± 0.072	5.699LeuGly: 5.699 ± 0.078	1.606LeuHis: 1.606 ± 0.041	6.145LeuIle: 6.145 ± 0.092	6.403LeuLys: 6.403 ± 0.078	8.213LeuLeu: 8.213 ± 0.103	2.581LeuMet: 2.581 ± 0.046	3.918LeuAsn: 3.918 ± 0.054	3.352LeuPro: 3.352 ± 0.059	2.84LeuGln: 2.84 ± 0.057	3.564LeuArg: 3.564 ± 0.056	5.823LeuSer: 5.823 ± 0.077	5.075LeuThr: 5.075 ± 0.066	5.193LeuVal: 5.193 ± 0.076	0.746LeuTrp: 0.746 ± 0.028	3.271LeuTyr: 3.271 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.409MetAla: 2.409 ± 0.041	0.367MetCys: 0.367 ± 0.018	1.905MetAsp: 1.905 ± 0.04	2.66MetGlu: 2.66 ± 0.055	1.053MetPhe: 1.053 ± 0.029	2.111MetGly: 2.111 ± 0.042	0.469MetHis: 0.469 ± 0.024	2.259MetIle: 2.259 ± 0.041	2.807MetLys: 2.807 ± 0.054	2.749MetLeu: 2.749 ± 0.055	0.964MetMet: 0.964 ± 0.031	1.67MetAsn: 1.67 ± 0.041	1.133MetPro: 1.133 ± 0.032	1.12MetGln: 1.12 ± 0.036	1.22MetArg: 1.22 ± 0.029	1.844MetSer: 1.844 ± 0.038	1.764MetThr: 1.764 ± 0.044	1.862MetVal: 1.862 ± 0.04	0.211MetTrp: 0.211 ± 0.014	0.93MetTyr: 0.93 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.16AsnAla: 3.16 ± 0.056	0.659AsnCys: 0.659 ± 0.024	2.199AsnAsp: 2.199 ± 0.046	2.963AsnGlu: 2.963 ± 0.052	1.671AsnPhe: 1.671 ± 0.031	3.65AsnGly: 3.65 ± 0.058	0.838AsnHis: 0.838 ± 0.03	3.485AsnIle: 3.485 ± 0.055	2.867AsnLys: 2.867 ± 0.053	3.934AsnLeu: 3.934 ± 0.05	1.459AsnMet: 1.459 ± 0.037	1.827AsnAsn: 1.827 ± 0.049	2.065AsnPro: 2.065 ± 0.041	1.487AsnGln: 1.487 ± 0.038	2.113AsnArg: 2.113 ± 0.047	2.416AsnSer: 2.416 ± 0.043	2.551AsnThr: 2.551 ± 0.055	2.903AsnVal: 2.903 ± 0.054	0.465AsnTrp: 0.465 ± 0.021	1.948AsnTyr: 1.948 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	2.418ProAla: 2.418 ± 0.046	0.413ProCys: 0.413 ± 0.019	2.461ProAsp: 2.461 ± 0.049	3.439ProGlu: 3.439 ± 0.062	1.464ProPhe: 1.464 ± 0.034	2.223ProGly: 2.223 ± 0.044	0.562ProHis: 0.562 ± 0.023	1.886ProIle: 1.886 ± 0.043	1.988ProLys: 1.988 ± 0.045	2.651ProLeu: 2.651 ± 0.042	0.866ProMet: 0.866 ± 0.026	1.188ProAsn: 1.188 ± 0.034	0.682ProPro: 0.682 ± 0.034	1.148ProGln: 1.148 ± 0.033	0.987ProArg: 0.987 ± 0.028	1.717ProSer: 1.717 ± 0.044	1.649ProThr: 1.649 ± 0.051	3.079ProVal: 3.079 ± 0.05	0.315ProTrp: 0.315 ± 0.016	1.454ProTyr: 1.454 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	2.488GlnAla: 2.488 ± 0.053	0.371GlnCys: 0.371 ± 0.017	1.713GlnAsp: 1.713 ± 0.038	2.967GlnGlu: 2.967 ± 0.06	1.127GlnPhe: 1.127 ± 0.03	2.037GlnGly: 2.037 ± 0.046	0.492GlnHis: 0.492 ± 0.022	2.727GlnIle: 2.727 ± 0.045	3.184GlnLys: 3.184 ± 0.056	2.76GlnLeu: 2.76 ± 0.056	1.282GlnMet: 1.282 ± 0.039	1.792GlnAsn: 1.792 ± 0.04	0.961GlnPro: 0.961 ± 0.028	1.262GlnGln: 1.262 ± 0.035	1.456GlnArg: 1.456 ± 0.04	1.665GlnSer: 1.665 ± 0.043	1.872GlnThr: 1.872 ± 0.043	2.056GlnVal: 2.056 ± 0.041	0.341GlnTrp: 0.341 ± 0.019	1.441GlnTyr: 1.441 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.5ArgAla: 2.5 ± 0.052	0.622ArgCys: 0.622 ± 0.025	2.132ArgAsp: 2.132 ± 0.045	3.731ArgGlu: 3.731 ± 0.074	1.801ArgPhe: 1.801 ± 0.041	2.353ArgGly: 2.353 ± 0.047	0.799ArgHis: 0.799 ± 0.026	3.5ArgIle: 3.5 ± 0.055	3.817ArgLys: 3.817 ± 0.065	3.632ArgLeu: 3.632 ± 0.063	1.494ArgMet: 1.494 ± 0.037	2.217ArgAsn: 2.217 ± 0.046	1.344ArgPro: 1.344 ± 0.038	1.777ArgGln: 1.777 ± 0.043	2.216ArgArg: 2.216 ± 0.049	2.149ArgSer: 2.149 ± 0.047	2.296ArgThr: 2.296 ± 0.042	2.506ArgVal: 2.506 ± 0.05	0.384ArgTrp: 0.384 ± 0.02	1.963ArgTyr: 1.963 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.175SerAla: 4.175 ± 0.071	0.883SerCys: 0.883 ± 0.03	3.606SerAsp: 3.606 ± 0.06	4.062SerGlu: 4.062 ± 0.058	2.575SerPhe: 2.575 ± 0.055	4.754SerGly: 4.754 ± 0.077	1.037SerHis: 1.037 ± 0.034	3.899SerIle: 3.899 ± 0.069	3.426SerLys: 3.426 ± 0.066	4.999SerLeu: 4.999 ± 0.071	1.813SerMet: 1.813 ± 0.034	2.223SerAsn: 2.223 ± 0.047	1.695SerPro: 1.695 ± 0.038	1.964SerGln: 1.964 ± 0.05	2.742SerArg: 2.742 ± 0.049	3.568SerSer: 3.568 ± 0.075	2.736SerThr: 2.736 ± 0.05	4.483SerVal: 4.483 ± 0.061	0.605SerTrp: 0.605 ± 0.024	2.504SerTyr: 2.504 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	4.568ThrAla: 4.568 ± 0.073	0.729ThrCys: 0.729 ± 0.026	3.624ThrAsp: 3.624 ± 0.062	4.228ThrGlu: 4.228 ± 0.069	2.148ThrPhe: 2.148 ± 0.046	4.829ThrGly: 4.829 ± 0.076	0.887ThrHis: 0.887 ± 0.031	3.812ThrIle: 3.812 ± 0.064	3.085ThrLys: 3.085 ± 0.052	4.741ThrLeu: 4.741 ± 0.059	1.418ThrMet: 1.418 ± 0.042	1.999ThrAsn: 1.999 ± 0.041	2.294ThrPro: 2.294 ± 0.057	1.604ThrGln: 1.604 ± 0.04	2.044ThrArg: 2.044 ± 0.041	3.1ThrSer: 3.1 ± 0.061	2.854ThrThr: 2.854 ± 0.059	4.723ThrVal: 4.723 ± 0.073	0.554ThrTrp: 0.554 ± 0.022	2.155ThrTyr: 2.155 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.483ValAla: 4.483 ± 0.072	1.224ValCys: 1.224 ± 0.036	3.727ValAsp: 3.727 ± 0.059	4.452ValGlu: 4.452 ± 0.068	2.953ValPhe: 2.953 ± 0.047	4.007ValGly: 4.007 ± 0.064	1.083ValHis: 1.083 ± 0.034	5.134ValIle: 5.134 ± 0.067	4.698ValLys: 4.698 ± 0.076	6.415ValLeu: 6.415 ± 0.083	2.066ValMet: 2.066 ± 0.04	2.971ValAsn: 2.971 ± 0.058	2.498ValPro: 2.498 ± 0.046	2.223ValGln: 2.223 ± 0.05	2.856ValArg: 2.856 ± 0.051	4.575ValSer: 4.575 ± 0.071	4.331ValThr: 4.331 ± 0.083	4.537ValVal: 4.537 ± 0.087	0.625ValTrp: 0.625 ± 0.025	2.707ValTyr: 2.707 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.559TrpAla: 0.559 ± 0.024	0.165TrpCys: 0.165 ± 0.012	0.514TrpAsp: 0.514 ± 0.02	0.698TrpGlu: 0.698 ± 0.025	0.406TrpPhe: 0.406 ± 0.019	0.618TrpGly: 0.618 ± 0.028	0.177TrpHis: 0.177 ± 0.012	0.725TrpIle: 0.725 ± 0.026	0.891TrpLys: 0.891 ± 0.03	0.836TrpLeu: 0.836 ± 0.031	0.331TrpMet: 0.331 ± 0.018	0.598TrpAsn: 0.598 ± 0.024	0.213TrpPro: 0.213 ± 0.015	0.383TrpGln: 0.383 ± 0.017	0.329TrpArg: 0.329 ± 0.017	0.521TrpSer: 0.521 ± 0.022	0.463TrpThr: 0.463 ± 0.021	0.524TrpVal: 0.524 ± 0.021	0.096TrpTrp: 0.096 ± 0.01	0.438TrpTyr: 0.438 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.724TyrAla: 2.724 ± 0.047	0.719TyrCys: 0.719 ± 0.024	2.672TyrAsp: 2.672 ± 0.056	3.126TyrGlu: 3.126 ± 0.053	1.877TyrPhe: 1.877 ± 0.043	3.001TyrGly: 3.001 ± 0.059	0.963TyrHis: 0.963 ± 0.03	2.856TyrIle: 2.856 ± 0.048	2.414TyrLys: 2.414 ± 0.05	3.937TyrLeu: 3.937 ± 0.064	1.152TyrMet: 1.152 ± 0.036	1.846TyrAsn: 1.846 ± 0.047	1.464TyrPro: 1.464 ± 0.032	1.565TyrGln: 1.565 ± 0.038	2.05TyrArg: 2.05 ± 0.046	2.439TyrSer: 2.439 ± 0.052	2.398TyrThr: 2.398 ± 0.049	2.639TyrVal: 2.639 ± 0.049	0.385TyrTrp: 0.385 ± 0.02	1.993TyrTyr: 1.993 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.011XaaXaa: 0.011 ± 0.01

Statistics based on 3715 proteins (1165781 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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