Amino acid dipepetide frequency for Bombyx mori densovirus 5 (isolate Shinshu) (BmDNV-5)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.943AlaAla: 2.943 ± 1.844
0.49AlaCys: 0.49 ± 0.375
3.923AlaAsp: 3.923 ± 0.946
4.904AlaGlu: 4.904 ± 1.738
2.943AlaPhe: 2.943 ± 0.729
4.414AlaGly: 4.414 ± 1.378
0.49AlaHis: 0.49 ± 0.375
3.433AlaIle: 3.433 ± 1.017
2.452AlaLys: 2.452 ± 0.683
3.433AlaLeu: 3.433 ± 0.656
0.49AlaMet: 0.49 ± 0.375
2.452AlaAsn: 2.452 ± 0.968
2.452AlaPro: 2.452 ± 1.826
3.433AlaGln: 3.433 ± 2.314
2.943AlaArg: 2.943 ± 1.844
2.452AlaSer: 2.452 ± 0.683
5.885AlaThr: 5.885 ± 1.27
1.471AlaVal: 1.471 ± 0.899
1.471AlaTrp: 1.471 ± 0.671
2.943AlaTyr: 2.943 ± 0.663
0.0AlaXaa: 0.0 ± 0.0
Cys
0.981CysAla: 0.981 ± 0.345
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.981CysGlu: 0.981 ± 0.345
0.981CysPhe: 0.981 ± 0.813
0.49CysGly: 0.49 ± 0.375
0.49CysHis: 0.49 ± 0.375
0.0CysIle: 0.0 ± 0.0
0.981CysLys: 0.981 ± 0.491
1.962CysLeu: 1.962 ± 1.463
0.49CysMet: 0.49 ± 0.375
0.0CysAsn: 0.0 ± 0.0
0.49CysPro: 0.49 ± 0.375
0.0CysGln: 0.0 ± 0.0
1.471CysArg: 1.471 ± 1.124
0.49CysSer: 0.49 ± 0.478
0.49CysThr: 0.49 ± 0.478
0.0CysVal: 0.0 ± 0.0
0.981CysTrp: 0.981 ± 0.813
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.943AspAla: 2.943 ± 0.573
1.471AspCys: 1.471 ± 1.566
0.981AspAsp: 0.981 ± 0.345
4.904AspGlu: 4.904 ± 1.168
3.923AspPhe: 3.923 ± 1.248
2.943AspGly: 2.943 ± 0.745
0.49AspHis: 0.49 ± 0.478
3.923AspIle: 3.923 ± 2.658
2.452AspLys: 2.452 ± 0.893
4.904AspLeu: 4.904 ± 1.483
0.0AspMet: 0.0 ± 0.0
2.452AspAsn: 2.452 ± 0.367
1.962AspPro: 1.962 ± 0.407
3.433AspGln: 3.433 ± 0.896
2.452AspArg: 2.452 ± 1.352
3.433AspSer: 3.433 ± 1.577
4.414AspThr: 4.414 ± 1.828
2.943AspVal: 2.943 ± 1.42
1.962AspTrp: 1.962 ± 0.606
3.433AspTyr: 3.433 ± 1.295
0.0AspXaa: 0.0 ± 0.0
Glu
2.943GluAla: 2.943 ± 0.448
0.49GluCys: 0.49 ± 0.375
5.885GluAsp: 5.885 ± 1.146
7.847GluGlu: 7.847 ± 2.762
4.904GluPhe: 4.904 ± 0.839
1.471GluGly: 1.471 ± 0.591
2.452GluHis: 2.452 ± 1.286
2.452GluIle: 2.452 ± 1.08
4.414GluLys: 4.414 ± 0.995
4.414GluLeu: 4.414 ± 1.502
1.471GluMet: 1.471 ± 0.788
2.943GluAsn: 2.943 ± 1.245
3.433GluPro: 3.433 ± 1.684
1.962GluGln: 1.962 ± 0.689
4.904GluArg: 4.904 ± 1.217
7.357GluSer: 7.357 ± 3.198
6.866GluThr: 6.866 ± 1.336
3.433GluVal: 3.433 ± 1.04
1.962GluTrp: 1.962 ± 0.471
2.452GluTyr: 2.452 ± 1.401
0.0GluXaa: 0.0 ± 0.0
Phe
1.962PheAla: 1.962 ± 1.053
0.49PheCys: 0.49 ± 0.478
2.452PheAsp: 2.452 ± 0.933
4.904PheGlu: 4.904 ± 1.978
2.943PhePhe: 2.943 ± 2.067
1.962PheGly: 1.962 ± 0.471
1.471PheHis: 1.471 ± 0.591
3.923PheIle: 3.923 ± 2.049
3.433PheLys: 3.433 ± 0.961
1.962PheLeu: 1.962 ± 1.52
1.471PheMet: 1.471 ± 1.044
0.49PheAsn: 0.49 ± 0.375
2.452PhePro: 2.452 ± 0.968
2.943PheGln: 2.943 ± 1.102
4.414PheArg: 4.414 ± 2.012
1.471PheSer: 1.471 ± 0.84
3.433PheThr: 3.433 ± 0.964
4.414PheVal: 4.414 ± 1.963
0.49PheTrp: 0.49 ± 0.754
1.471PheTyr: 1.471 ± 0.731
0.0PheXaa: 0.0 ± 0.0
Gly
3.923GlyAla: 3.923 ± 0.941
0.49GlyCys: 0.49 ± 0.41
0.0GlyAsp: 0.0 ± 0.0
2.452GlyGlu: 2.452 ± 0.367
0.981GlyPhe: 0.981 ± 0.345
4.904GlyGly: 4.904 ± 2.243
1.962GlyHis: 1.962 ± 0.407
2.943GlyIle: 2.943 ± 1.318
2.943GlyLys: 2.943 ± 1.318
3.433GlyLeu: 3.433 ± 1.649
1.471GlyMet: 1.471 ± 1.231
1.962GlyAsn: 1.962 ± 0.689
2.943GlyPro: 2.943 ± 0.501
1.962GlyGln: 1.962 ± 0.471
4.414GlyArg: 4.414 ± 1.068
2.452GlySer: 2.452 ± 0.847
4.904GlyThr: 4.904 ± 1.261
3.433GlyVal: 3.433 ± 1.285
0.981GlyTrp: 0.981 ± 1.509
2.452GlyTyr: 2.452 ± 0.968
0.0GlyXaa: 0.0 ± 0.0
His
0.981HisAla: 0.981 ± 0.491
0.0HisCys: 0.0 ± 0.0
1.471HisAsp: 1.471 ± 0.591
0.981HisGlu: 0.981 ± 0.75
2.452HisPhe: 2.452 ± 1.125
1.471HisGly: 1.471 ± 0.25
0.49HisHis: 0.49 ± 0.41
2.943HisIle: 2.943 ± 1.102
1.471HisLys: 1.471 ± 0.659
0.981HisLeu: 0.981 ± 0.345
0.0HisMet: 0.0 ± 0.0
1.471HisAsn: 1.471 ± 0.591
1.471HisPro: 1.471 ± 0.894
0.49HisGln: 0.49 ± 0.375
0.49HisArg: 0.49 ± 0.375
1.962HisSer: 1.962 ± 0.681
1.471HisThr: 1.471 ± 0.659
0.981HisVal: 0.981 ± 0.821
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.962IleAla: 1.962 ± 0.471
0.981IleCys: 0.981 ± 1.509
2.943IleAsp: 2.943 ± 1.347
4.904IleGlu: 4.904 ± 2.803
0.49IlePhe: 0.49 ± 0.41
2.452IleGly: 2.452 ± 1.441
0.981IleHis: 0.981 ± 0.821
2.943IleIle: 2.943 ± 0.745
3.923IleLys: 3.923 ± 0.602
6.376IleLeu: 6.376 ± 1.983
1.471IleMet: 1.471 ± 0.25
3.923IleAsn: 3.923 ± 2.259
2.943IlePro: 2.943 ± 1.034
3.923IleGln: 3.923 ± 1.535
4.904IleArg: 4.904 ± 0.733
2.943IleSer: 2.943 ± 1.081
2.943IleThr: 2.943 ± 0.834
2.943IleVal: 2.943 ± 1.42
0.981IleTrp: 0.981 ± 0.75
1.471IleTyr: 1.471 ± 0.25
0.0IleXaa: 0.0 ± 0.0
Lys
2.452LysAla: 2.452 ± 0.556
0.981LysCys: 0.981 ± 0.821
2.452LysAsp: 2.452 ± 0.367
4.414LysGlu: 4.414 ± 1.624
2.943LysPhe: 2.943 ± 1.102
1.962LysGly: 1.962 ± 0.681
0.981LysHis: 0.981 ± 0.345
1.471LysIle: 1.471 ± 0.591
3.923LysLys: 3.923 ± 1.432
5.395LysLeu: 5.395 ± 1.119
0.981LysMet: 0.981 ± 0.376
4.414LysAsn: 4.414 ± 1.071
2.452LysPro: 2.452 ± 0.968
2.452LysGln: 2.452 ± 0.663
5.885LysArg: 5.885 ± 1.146
4.904LysSer: 4.904 ± 2.535
3.433LysThr: 3.433 ± 1.139
3.433LysVal: 3.433 ± 0.632
2.452LysTrp: 2.452 ± 1.15
2.452LysTyr: 2.452 ± 1.08
0.0LysXaa: 0.0 ± 0.0
Leu
3.433LeuAla: 3.433 ± 1.04
1.962LeuCys: 1.962 ± 0.982
4.414LeuAsp: 4.414 ± 1.923
4.904LeuGlu: 4.904 ± 0.92
2.452LeuPhe: 2.452 ± 1.626
4.414LeuGly: 4.414 ± 2.033
1.471LeuHis: 1.471 ± 1.124
2.943LeuIle: 2.943 ± 1.458
5.395LeuLys: 5.395 ± 1.728
8.337LeuLeu: 8.337 ± 1.619
1.962LeuMet: 1.962 ± 0.702
4.414LeuAsn: 4.414 ± 0.628
3.923LeuPro: 3.923 ± 1.649
2.943LeuGln: 2.943 ± 1.08
2.943LeuArg: 2.943 ± 0.932
3.923LeuSer: 3.923 ± 2.147
3.923LeuThr: 3.923 ± 1.533
3.923LeuVal: 3.923 ± 0.873
0.49LeuTrp: 0.49 ± 0.478
2.452LeuTyr: 2.452 ± 0.367
0.0LeuXaa: 0.0 ± 0.0
Met
0.49MetAla: 0.49 ± 0.754
0.0MetCys: 0.0 ± 0.0
0.49MetAsp: 0.49 ± 0.41
2.943MetGlu: 2.943 ± 0.729
1.962MetPhe: 1.962 ± 0.606
1.471MetGly: 1.471 ± 1.231
0.49MetHis: 0.49 ± 0.375
0.981MetIle: 0.981 ± 0.49
2.943MetLys: 2.943 ± 2.283
0.981MetLeu: 0.981 ± 0.491
0.981MetMet: 0.981 ± 0.956
0.981MetAsn: 0.981 ± 0.491
1.471MetPro: 1.471 ± 0.659
0.49MetGln: 0.49 ± 0.478
0.49MetArg: 0.49 ± 0.375
2.452MetSer: 2.452 ± 0.683
0.981MetThr: 0.981 ± 0.345
0.49MetVal: 0.49 ± 0.375
0.0MetTrp: 0.0 ± 0.0
0.49MetTyr: 0.49 ± 0.41
0.0MetXaa: 0.0 ± 0.0
Asn
4.904AsnAla: 4.904 ± 1.694
0.0AsnCys: 0.0 ± 0.0
3.433AsnAsp: 3.433 ± 1.217
2.452AsnGlu: 2.452 ± 0.742
2.943AsnPhe: 2.943 ± 1.102
3.433AsnGly: 3.433 ± 1.275
0.981AsnHis: 0.981 ± 0.813
3.923AsnIle: 3.923 ± 1.436
3.433AsnLys: 3.433 ± 0.563
1.962AsnLeu: 1.962 ± 1.129
0.981AsnMet: 0.981 ± 0.491
4.414AsnAsn: 4.414 ± 0.756
2.943AsnPro: 2.943 ± 0.573
2.943AsnGln: 2.943 ± 1.535
4.414AsnArg: 4.414 ± 1.775
5.395AsnSer: 5.395 ± 2.934
3.923AsnThr: 3.923 ± 2.106
3.433AsnVal: 3.433 ± 1.295
0.49AsnTrp: 0.49 ± 0.478
2.943AsnTyr: 2.943 ± 1.034
0.0AsnXaa: 0.0 ± 0.0
Pro
1.471ProAla: 1.471 ± 0.788
0.49ProCys: 0.49 ± 0.375
3.433ProAsp: 3.433 ± 0.539
2.943ProGlu: 2.943 ± 0.745
2.452ProPhe: 2.452 ± 0.933
1.962ProGly: 1.962 ± 1.042
0.49ProHis: 0.49 ± 0.375
3.923ProIle: 3.923 ± 1.378
2.452ProLys: 2.452 ± 0.367
3.433ProLeu: 3.433 ± 0.632
0.49ProMet: 0.49 ± 0.41
2.943ProAsn: 2.943 ± 0.932
2.943ProPro: 2.943 ± 0.977
1.471ProGln: 1.471 ± 1.231
3.433ProArg: 3.433 ± 0.896
3.923ProSer: 3.923 ± 1.012
5.885ProThr: 5.885 ± 1.019
4.904ProVal: 4.904 ± 1.723
1.471ProTrp: 1.471 ± 0.84
0.981ProTyr: 0.981 ± 0.821
0.0ProXaa: 0.0 ± 0.0
Gln
2.452GlnAla: 2.452 ± 0.847
0.0GlnCys: 0.0 ± 0.0
1.962GlnAsp: 1.962 ± 0.471
1.962GlnGlu: 1.962 ± 0.471
1.962GlnPhe: 1.962 ± 0.689
0.981GlnGly: 0.981 ± 0.491
0.981GlnHis: 0.981 ± 0.49
3.433GlnIle: 3.433 ± 1.11
4.414GlnLys: 4.414 ± 0.991
2.943GlnLeu: 2.943 ± 1.462
1.962GlnMet: 1.962 ± 0.982
2.452GlnAsn: 2.452 ± 0.663
3.433GlnPro: 3.433 ± 1.649
3.433GlnGln: 3.433 ± 0.896
1.471GlnArg: 1.471 ± 0.25
5.395GlnSer: 5.395 ± 1.137
0.0GlnThr: 0.0 ± 0.0
0.981GlnVal: 0.981 ± 0.49
0.0GlnTrp: 0.0 ± 0.0
1.962GlnTyr: 1.962 ± 1.129
0.0GlnXaa: 0.0 ± 0.0
Arg
4.904ArgAla: 4.904 ± 0.933
1.471ArgCys: 1.471 ± 1.124
2.943ArgAsp: 2.943 ± 1.476
4.904ArgGlu: 4.904 ± 1.261
2.943ArgPhe: 2.943 ± 1.341
1.962ArgGly: 1.962 ± 1.499
2.452ArgHis: 2.452 ± 0.683
5.885ArgIle: 5.885 ± 1.019
2.452ArgLys: 2.452 ± 1.15
3.923ArgLeu: 3.923 ± 0.853
1.471ArgMet: 1.471 ± 0.877
4.904ArgAsn: 4.904 ± 1.835
3.433ArgPro: 3.433 ± 0.563
0.49ArgGln: 0.49 ± 0.478
4.904ArgArg: 4.904 ± 1.978
3.923ArgSer: 3.923 ± 0.521
2.943ArgThr: 2.943 ± 0.448
2.452ArgVal: 2.452 ± 2.171
1.471ArgTrp: 1.471 ± 0.731
2.943ArgTyr: 2.943 ± 1.225
0.0ArgXaa: 0.0 ± 0.0
Ser
5.885SerAla: 5.885 ± 2.134
0.49SerCys: 0.49 ± 0.375
2.452SerAsp: 2.452 ± 1.453
4.904SerGlu: 4.904 ± 1.003
2.452SerPhe: 2.452 ± 0.556
5.395SerGly: 5.395 ± 0.736
0.49SerHis: 0.49 ± 0.41
3.433SerIle: 3.433 ± 1.664
3.433SerLys: 3.433 ± 1.121
7.847SerLeu: 7.847 ± 3.299
0.981SerMet: 0.981 ± 0.49
4.414SerAsn: 4.414 ± 1.29
1.471SerPro: 1.471 ± 0.671
3.923SerGln: 3.923 ± 1.306
4.904SerArg: 4.904 ± 0.819
8.828SerSer: 8.828 ± 3.586
5.885SerThr: 5.885 ± 2.256
3.923SerVal: 3.923 ± 2.117
0.981SerTrp: 0.981 ± 0.491
2.943SerTyr: 2.943 ± 0.834
0.0SerXaa: 0.0 ± 0.0
Thr
3.923ThrAla: 3.923 ± 1.436
0.0ThrCys: 0.0 ± 0.0
4.904ThrAsp: 4.904 ± 1.145
3.923ThrGlu: 3.923 ± 1.432
1.962ThrPhe: 1.962 ± 0.928
3.433ThrGly: 3.433 ± 1.295
0.49ThrHis: 0.49 ± 0.478
3.433ThrIle: 3.433 ± 1.535
4.904ThrLys: 4.904 ± 0.269
3.433ThrLeu: 3.433 ± 1.525
2.452ThrMet: 2.452 ± 0.663
4.904ThrAsn: 4.904 ± 1.772
4.904ThrPro: 4.904 ± 0.582
3.923ThrGln: 3.923 ± 0.904
4.414ThrArg: 4.414 ± 1.648
5.395ThrSer: 5.395 ± 2.642
5.885ThrThr: 5.885 ± 2.942
2.943ThrVal: 2.943 ± 0.834
0.49ThrTrp: 0.49 ± 0.375
2.943ThrTyr: 2.943 ± 1.462
0.0ThrXaa: 0.0 ± 0.0
Val
3.923ValAla: 3.923 ± 2.239
0.981ValCys: 0.981 ± 0.345
5.395ValAsp: 5.395 ± 1.077
4.414ValGlu: 4.414 ± 0.628
2.452ValPhe: 2.452 ± 2.128
2.452ValGly: 2.452 ± 0.754
2.452ValHis: 2.452 ± 0.367
3.433ValIle: 3.433 ± 0.806
2.452ValLys: 2.452 ± 1.626
1.962ValLeu: 1.962 ± 0.407
0.981ValMet: 0.981 ± 0.783
4.904ValAsn: 4.904 ± 0.894
1.962ValPro: 1.962 ± 0.83
0.49ValGln: 0.49 ± 0.375
2.452ValArg: 2.452 ± 0.556
3.923ValSer: 3.923 ± 2.751
2.943ValThr: 2.943 ± 1.844
3.923ValVal: 3.923 ± 3.731
0.49ValTrp: 0.49 ± 0.375
2.943ValTyr: 2.943 ± 1.183
0.0ValXaa: 0.0 ± 0.0
Trp
0.49TrpAla: 0.49 ± 0.41
0.0TrpCys: 0.0 ± 0.0
1.962TrpAsp: 1.962 ± 0.407
1.962TrpGlu: 1.962 ± 0.471
1.471TrpPhe: 1.471 ± 0.788
0.981TrpGly: 0.981 ± 0.75
0.0TrpHis: 0.0 ± 0.0
0.49TrpIle: 0.49 ± 0.754
0.981TrpLys: 0.981 ± 0.49
1.471TrpLeu: 1.471 ± 1.447
0.0TrpMet: 0.0 ± 0.0
1.962TrpAsn: 1.962 ± 1.346
1.962TrpPro: 1.962 ± 1.053
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.962TrpSer: 1.962 ± 1.099
0.0TrpThr: 0.0 ± 0.0
1.962TrpVal: 1.962 ± 1.385
0.0TrpTrp: 0.0 ± 0.0
0.981TrpTyr: 0.981 ± 0.75
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.452TyrAla: 2.452 ± 0.683
0.49TyrCys: 0.49 ± 0.375
3.923TyrAsp: 3.923 ± 1.375
2.452TyrGlu: 2.452 ± 0.742
2.943TyrPhe: 2.943 ± 1.245
2.452TyrGly: 2.452 ± 1.441
1.471TyrHis: 1.471 ± 0.659
0.49TyrIle: 0.49 ± 0.375
0.981TyrLys: 0.981 ± 0.75
1.962TyrLeu: 1.962 ± 0.681
0.981TyrMet: 0.981 ± 0.452
2.943TyrAsn: 2.943 ± 1.102
2.452TyrPro: 2.452 ± 0.893
1.471TyrGln: 1.471 ± 0.731
1.471TyrArg: 1.471 ± 0.731
2.452TyrSer: 2.452 ± 0.893
2.452TyrThr: 2.452 ± 0.367
2.943TyrVal: 2.943 ± 0.853
1.471TyrTrp: 1.471 ± 1.124
2.943TyrTyr: 2.943 ± 1.102
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2040 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski