Amino acid dipepetide frequency for Succinivibrio dextrinosolvens DSM 3072

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.239AlaAla: 6.239 ± 0.141	1.111AlaCys: 1.111 ± 0.045	4.26AlaAsp: 4.26 ± 0.077	4.31AlaGlu: 4.31 ± 0.088	3.166AlaPhe: 3.166 ± 0.068	4.837AlaGly: 4.837 ± 0.077	1.244AlaHis: 1.244 ± 0.044	5.357AlaIle: 5.357 ± 0.098	5.332AlaLys: 5.332 ± 0.101	7.951AlaLeu: 7.951 ± 0.11	2.119AlaMet: 2.119 ± 0.057	3.192AlaAsn: 3.192 ± 0.07	2.416AlaPro: 2.416 ± 0.073	2.652AlaGln: 2.652 ± 0.071	3.054AlaArg: 3.054 ± 0.07	4.827AlaSer: 4.827 ± 0.1	3.576AlaThr: 3.576 ± 0.074	5.845AlaVal: 5.845 ± 0.094	0.509AlaTrp: 0.509 ± 0.027	2.465AlaTyr: 2.465 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	1.094CysAla: 1.094 ± 0.04	0.269CysCys: 0.269 ± 0.019	0.808CysAsp: 0.808 ± 0.034	0.833CysGlu: 0.833 ± 0.034	0.64CysPhe: 0.64 ± 0.033	1.18CysGly: 1.18 ± 0.045	0.321CysHis: 0.321 ± 0.018	1.065CysIle: 1.065 ± 0.039	0.808CysLys: 0.808 ± 0.035	1.115CysLeu: 1.115 ± 0.036	0.372CysMet: 0.372 ± 0.023	0.713CysAsn: 0.713 ± 0.035	0.549CysPro: 0.549 ± 0.026	0.38CysGln: 0.38 ± 0.023	0.594CysArg: 0.594 ± 0.031	1.09CysSer: 1.09 ± 0.041	0.696CysThr: 0.696 ± 0.03	0.952CysVal: 0.952 ± 0.039	0.088CysTrp: 0.088 ± 0.011	0.567CysTyr: 0.567 ± 0.027	0.0CysXaa: 0.0 ± 0.0
Asp	4.061AspAla: 4.061 ± 0.073	0.779AspCys: 0.779 ± 0.034	3.339AspAsp: 3.339 ± 0.074	4.449AspGlu: 4.449 ± 0.088	3.136AspPhe: 3.136 ± 0.063	3.732AspGly: 3.732 ± 0.075	0.89AspHis: 0.89 ± 0.035	4.632AspIle: 4.632 ± 0.085	4.51AspLys: 4.51 ± 0.085	5.781AspLeu: 5.781 ± 0.097	1.424AspMet: 1.424 ± 0.046	3.112AspAsn: 3.112 ± 0.062	2.183AspPro: 2.183 ± 0.062	1.155AspGln: 1.155 ± 0.035	2.477AspArg: 2.477 ± 0.058	4.143AspSer: 4.143 ± 0.076	2.685AspThr: 2.685 ± 0.052	4.013AspVal: 4.013 ± 0.065	0.458AspTrp: 0.458 ± 0.024	2.586AspTyr: 2.586 ± 0.063	0.0AspXaa: 0.0 ± 0.0
Glu	4.582GluAla: 4.582 ± 0.087	0.781GluCys: 0.781 ± 0.037	3.724GluAsp: 3.724 ± 0.074	4.491GluGlu: 4.491 ± 0.092	2.848GluPhe: 2.848 ± 0.061	3.622GluGly: 3.622 ± 0.076	1.309GluHis: 1.309 ± 0.042	5.064GluIle: 5.064 ± 0.089	5.561GluLys: 5.561 ± 0.095	6.532GluLeu: 6.532 ± 0.101	1.53GluMet: 1.53 ± 0.044	4.182GluAsn: 4.182 ± 0.085	1.746GluPro: 1.746 ± 0.052	2.451GluGln: 2.451 ± 0.057	2.598GluArg: 2.598 ± 0.063	3.866GluSer: 3.866 ± 0.078	2.727GluThr: 2.727 ± 0.069	3.968GluVal: 3.968 ± 0.074	0.455GluTrp: 0.455 ± 0.029	2.375GluTyr: 2.375 ± 0.056	0.0GluXaa: 0.0 ± 0.0
Phe	3.269PheAla: 3.269 ± 0.074	0.756PheCys: 0.756 ± 0.032	3.177PheAsp: 3.177 ± 0.066	2.918PheGlu: 2.918 ± 0.062	2.369PhePhe: 2.369 ± 0.071	3.138PheGly: 3.138 ± 0.075	0.639PheHis: 0.639 ± 0.03	3.615PheIle: 3.615 ± 0.088	3.123PheLys: 3.123 ± 0.055	3.925PheLeu: 3.925 ± 0.084	1.163PheMet: 1.163 ± 0.043	2.571PheAsn: 2.571 ± 0.065	1.348PhePro: 1.348 ± 0.044	0.836PheGln: 0.836 ± 0.033	1.702PheArg: 1.702 ± 0.054	3.865PheSer: 3.865 ± 0.076	2.427PheThr: 2.427 ± 0.059	3.155PheVal: 3.155 ± 0.068	0.332PheTrp: 0.332 ± 0.022	1.696PheTyr: 1.696 ± 0.053	0.0PheXaa: 0.0 ± 0.0
Gly	4.77GlyAla: 4.77 ± 0.086	1.051GlyCys: 1.051 ± 0.049	3.369GlyAsp: 3.369 ± 0.065	3.577GlyGlu: 3.577 ± 0.076	3.352GlyPhe: 3.352 ± 0.068	3.991GlyGly: 3.991 ± 0.089	1.211GlyHis: 1.211 ± 0.041	5.452GlyIle: 5.452 ± 0.086	4.643GlyLys: 4.643 ± 0.084	5.795GlyLeu: 5.795 ± 0.108	1.842GlyMet: 1.842 ± 0.054	2.794GlyAsn: 2.794 ± 0.056	1.577GlyPro: 1.577 ± 0.047	1.832GlyGln: 1.832 ± 0.055	2.608GlyArg: 2.608 ± 0.063	4.253GlySer: 4.253 ± 0.087	3.497GlyThr: 3.497 ± 0.072	4.666GlyVal: 4.666 ± 0.09	0.505GlyTrp: 0.505 ± 0.023	2.668GlyTyr: 2.668 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	1.069HisAla: 1.069 ± 0.036	0.307HisCys: 0.307 ± 0.021	1.004HisAsp: 1.004 ± 0.042	1.098HisGlu: 1.098 ± 0.035	0.807HisPhe: 0.807 ± 0.034	1.228HisGly: 1.228 ± 0.04	0.403HisHis: 0.403 ± 0.03	1.293HisIle: 1.293 ± 0.044	1.095HisLys: 1.095 ± 0.038	1.518HisLeu: 1.518 ± 0.041	0.432HisMet: 0.432 ± 0.024	0.924HisAsn: 0.924 ± 0.033	0.846HisPro: 0.846 ± 0.032	0.527HisGln: 0.527 ± 0.024	0.755HisArg: 0.755 ± 0.033	1.181HisSer: 1.181 ± 0.047	0.826HisThr: 0.826 ± 0.037	1.06HisVal: 1.06 ± 0.039	0.133HisTrp: 0.133 ± 0.014	0.669HisTyr: 0.669 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.945IleAla: 5.945 ± 0.103	1.225IleCys: 1.225 ± 0.044	4.798IleAsp: 4.798 ± 0.088	4.872IleGlu: 4.872 ± 0.098	3.172IlePhe: 3.172 ± 0.077	4.873IleGly: 4.873 ± 0.106	1.195IleHis: 1.195 ± 0.043	5.455IleIle: 5.455 ± 0.117	5.334IleLys: 5.334 ± 0.093	6.508IleLeu: 6.508 ± 0.105	1.621IleMet: 1.621 ± 0.044	3.701IleAsn: 3.701 ± 0.072	3.087IlePro: 3.087 ± 0.071	1.882IleGln: 1.882 ± 0.053	3.282IleArg: 3.282 ± 0.064	6.124IleSer: 6.124 ± 0.098	4.178IleThr: 4.178 ± 0.077	4.649IleVal: 4.649 ± 0.096	0.485IleTrp: 0.485 ± 0.023	2.401IleTyr: 2.401 ± 0.063	0.0IleXaa: 0.0 ± 0.0
Lys	5.928LysAla: 5.928 ± 0.098	0.774LysCys: 0.774 ± 0.031	4.777LysAsp: 4.777 ± 0.081	5.49LysGlu: 5.49 ± 0.086	2.638LysPhe: 2.638 ± 0.067	4.159LysGly: 4.159 ± 0.081	1.103LysHis: 1.103 ± 0.038	5.413LysIle: 5.413 ± 0.088	6.132LysLys: 6.132 ± 0.11	6.67LysLeu: 6.67 ± 0.104	1.761LysMet: 1.761 ± 0.047	4.363LysAsn: 4.363 ± 0.083	2.149LysPro: 2.149 ± 0.06	2.195LysGln: 2.195 ± 0.045	2.793LysArg: 2.793 ± 0.072	4.619LysSer: 4.619 ± 0.086	4.044LysThr: 4.044 ± 0.077	4.818LysVal: 4.818 ± 0.091	0.545LysTrp: 0.545 ± 0.03	2.698LysTyr: 2.698 ± 0.066	0.0LysXaa: 0.0 ± 0.0
Leu	6.698LeuAla: 6.698 ± 0.102	1.644LeuCys: 1.644 ± 0.055	5.585LeuAsp: 5.585 ± 0.099	5.73LeuGlu: 5.73 ± 0.095	4.282LeuPhe: 4.282 ± 0.095	6.24LeuGly: 6.24 ± 0.103	1.493LeuHis: 1.493 ± 0.045	6.564LeuIle: 6.564 ± 0.11	7.93LeuLys: 7.93 ± 0.114	8.427LeuLeu: 8.427 ± 0.105	2.292LeuMet: 2.292 ± 0.047	5.509LeuAsn: 5.509 ± 0.09	3.759LeuPro: 3.759 ± 0.073	2.613LeuGln: 2.613 ± 0.059	3.916LeuArg: 3.916 ± 0.077	7.874LeuSer: 7.874 ± 0.109	4.852LeuThr: 4.852 ± 0.087	5.599LeuVal: 5.599 ± 0.1	0.679LeuTrp: 0.679 ± 0.03	3.227LeuTyr: 3.227 ± 0.066	0.0LeuXaa: 0.0 ± 0.0
Met	1.979MetAla: 1.979 ± 0.05	0.337MetCys: 0.337 ± 0.021	1.313MetAsp: 1.313 ± 0.047	1.316MetGlu: 1.316 ± 0.046	1.08MetPhe: 1.08 ± 0.039	1.476MetGly: 1.476 ± 0.048	0.454MetHis: 0.454 ± 0.022	1.731MetIle: 1.731 ± 0.048	1.77MetLys: 1.77 ± 0.045	2.465MetLeu: 2.465 ± 0.064	0.74MetMet: 0.74 ± 0.032	1.337MetAsn: 1.337 ± 0.044	1.05MetPro: 1.05 ± 0.038	0.986MetGln: 0.986 ± 0.039	1.065MetArg: 1.065 ± 0.034	1.949MetSer: 1.949 ± 0.05	1.458MetThr: 1.458 ± 0.049	1.631MetVal: 1.631 ± 0.051	0.176MetTrp: 0.176 ± 0.016	0.741MetTyr: 0.741 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.774AsnAla: 3.774 ± 0.071	0.739AsnCys: 0.739 ± 0.033	2.811AsnAsp: 2.811 ± 0.064	3.183AsnGlu: 3.183 ± 0.077	2.292AsnPhe: 2.292 ± 0.058	3.458AsnGly: 3.458 ± 0.07	0.905AsnHis: 0.905 ± 0.034	4.064AsnIle: 4.064 ± 0.079	3.335AsnLys: 3.335 ± 0.068	5.085AsnLeu: 5.085 ± 0.084	1.231AsnMet: 1.231 ± 0.034	2.842AsnAsn: 2.842 ± 0.088	2.269AsnPro: 2.269 ± 0.058	1.657AsnGln: 1.657 ± 0.056	2.213AsnArg: 2.213 ± 0.05	3.925AsnSer: 3.925 ± 0.083	2.733AsnThr: 2.733 ± 0.065	3.335AsnVal: 3.335 ± 0.072	0.407AsnTrp: 0.407 ± 0.024	2.002AsnTyr: 2.002 ± 0.054	0.0AsnXaa: 0.0 ± 0.0
Pro	2.496ProAla: 2.496 ± 0.082	0.429ProCys: 0.429 ± 0.026	2.312ProAsp: 2.312 ± 0.062	2.861ProGlu: 2.861 ± 0.066	1.695ProPhe: 1.695 ± 0.049	1.953ProGly: 1.953 ± 0.049	0.615ProHis: 0.615 ± 0.03	2.218ProIle: 2.218 ± 0.065	2.256ProLys: 2.256 ± 0.052	3.235ProLeu: 3.235 ± 0.064	0.839ProMet: 0.839 ± 0.033	1.66ProAsn: 1.66 ± 0.055	0.948ProPro: 0.948 ± 0.036	1.216ProGln: 1.216 ± 0.043	1.24ProArg: 1.24 ± 0.041	2.391ProSer: 2.391 ± 0.063	1.562ProThr: 1.562 ± 0.047	2.876ProVal: 2.876 ± 0.057	0.289ProTrp: 0.289 ± 0.021	1.445ProTyr: 1.445 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	2.12GlnAla: 2.12 ± 0.062	0.354GlnCys: 0.354 ± 0.022	1.5GlnAsp: 1.5 ± 0.049	1.902GlnGlu: 1.902 ± 0.061	1.189GlnPhe: 1.189 ± 0.04	1.852GlnGly: 1.852 ± 0.048	0.488GlnHis: 0.488 ± 0.025	2.492GlnIle: 2.492 ± 0.058	2.577GlnLys: 2.577 ± 0.061	2.703GlnLeu: 2.703 ± 0.067	0.917GlnMet: 0.917 ± 0.033	1.94GlnAsn: 1.94 ± 0.07	0.796GlnPro: 0.796 ± 0.039	0.989GlnGln: 0.989 ± 0.038	1.447GlnArg: 1.447 ± 0.04	2.018GlnSer: 2.018 ± 0.047	1.648GlnThr: 1.648 ± 0.05	1.855GlnVal: 1.855 ± 0.054	0.237GlnTrp: 0.237 ± 0.018	1.062GlnTyr: 1.062 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.979ArgAla: 2.979 ± 0.071	0.424ArgCys: 0.424 ± 0.021	2.357ArgAsp: 2.357 ± 0.054	2.862ArgGlu: 2.862 ± 0.062	2.087ArgPhe: 2.087 ± 0.05	2.327ArgGly: 2.327 ± 0.06	0.786ArgHis: 0.786 ± 0.028	3.374ArgIle: 3.374 ± 0.07	2.963ArgLys: 2.963 ± 0.073	4.048ArgLeu: 4.048 ± 0.083	1.112ArgMet: 1.112 ± 0.038	2.312ArgAsn: 2.312 ± 0.067	1.342ArgPro: 1.342 ± 0.043	1.465ArgGln: 1.465 ± 0.046	1.988ArgArg: 1.988 ± 0.055	2.404ArgSer: 2.404 ± 0.051	1.971ArgThr: 1.971 ± 0.051	2.612ArgVal: 2.612 ± 0.071	0.267ArgTrp: 0.267 ± 0.019	1.599ArgTyr: 1.599 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	5.062SerAla: 5.062 ± 0.084	0.921SerCys: 0.921 ± 0.036	4.597SerAsp: 4.597 ± 0.087	4.621SerGlu: 4.621 ± 0.092	3.717SerPhe: 3.717 ± 0.078	4.837SerGly: 4.837 ± 0.086	1.285SerHis: 1.285 ± 0.044	5.144SerIle: 5.144 ± 0.083	4.939SerLys: 4.939 ± 0.09	7.146SerLeu: 7.146 ± 0.099	1.808SerMet: 1.808 ± 0.053	3.325SerAsn: 3.325 ± 0.082	2.193SerPro: 2.193 ± 0.051	2.291SerGln: 2.291 ± 0.055	2.842SerArg: 2.842 ± 0.062	5.663SerSer: 5.663 ± 0.123	3.395SerThr: 3.395 ± 0.076	5.033SerVal: 5.033 ± 0.088	0.553SerTrp: 0.553 ± 0.029	2.698SerTyr: 2.698 ± 0.065	0.0SerXaa: 0.0 ± 0.0
Thr	4.189ThrAla: 4.189 ± 0.082	0.579ThrCys: 0.579 ± 0.028	3.129ThrAsp: 3.129 ± 0.062	3.002ThrGlu: 3.002 ± 0.063	2.275ThrPhe: 2.275 ± 0.064	3.619ThrGly: 3.619 ± 0.072	0.875ThrHis: 0.875 ± 0.034	3.507ThrIle: 3.507 ± 0.072	2.966ThrLys: 2.966 ± 0.067	5.261ThrLeu: 5.261 ± 0.088	1.055ThrMet: 1.055 ± 0.04	2.14ThrAsn: 2.14 ± 0.057	2.3ThrPro: 2.3 ± 0.062	1.569ThrGln: 1.569 ± 0.049	1.968ThrArg: 1.968 ± 0.059	3.674ThrSer: 3.674 ± 0.086	2.757ThrThr: 2.757 ± 0.075	4.121ThrVal: 4.121 ± 0.071	0.345ThrTrp: 0.345 ± 0.019	1.695ThrTyr: 1.695 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	5.123ValAla: 5.123 ± 0.097	1.034ValCys: 1.034 ± 0.039	3.979ValAsp: 3.979 ± 0.08	4.234ValGlu: 4.234 ± 0.072	3.114ValPhe: 3.114 ± 0.069	4.147ValGly: 4.147 ± 0.087	1.082ValHis: 1.082 ± 0.036	5.301ValIle: 5.301 ± 0.088	4.799ValLys: 4.799 ± 0.086	6.424ValLeu: 6.424 ± 0.089	1.716ValMet: 1.716 ± 0.048	3.48ValAsn: 3.48 ± 0.066	2.472ValPro: 2.472 ± 0.054	1.869ValGln: 1.869 ± 0.053	2.749ValArg: 2.749 ± 0.068	5.124ValSer: 5.124 ± 0.097	3.718ValThr: 3.718 ± 0.067	4.859ValVal: 4.859 ± 0.088	0.44ValTrp: 0.44 ± 0.025	2.206ValTyr: 2.206 ± 0.062	0.0ValXaa: 0.0 ± 0.0
Trp	0.463TrpAla: 0.463 ± 0.024	0.134TrpCys: 0.134 ± 0.012	0.471TrpAsp: 0.471 ± 0.029	0.371TrpGlu: 0.371 ± 0.027	0.388TrpPhe: 0.388 ± 0.024	0.429TrpGly: 0.429 ± 0.022	0.194TrpHis: 0.194 ± 0.018	0.498TrpIle: 0.498 ± 0.026	0.433TrpLys: 0.433 ± 0.026	0.723TrpLeu: 0.723 ± 0.032	0.208TrpMet: 0.208 ± 0.016	0.412TrpAsn: 0.412 ± 0.027	0.215TrpPro: 0.215 ± 0.019	0.3TrpGln: 0.3 ± 0.018	0.33TrpArg: 0.33 ± 0.021	0.484TrpSer: 0.484 ± 0.027	0.354TrpThr: 0.354 ± 0.024	0.436TrpVal: 0.436 ± 0.026	0.1TrpTrp: 0.1 ± 0.011	0.325TrpTyr: 0.325 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.623TyrAla: 2.623 ± 0.063	0.487TyrCys: 0.487 ± 0.031	2.237TyrAsp: 2.237 ± 0.057	2.291TyrGlu: 2.291 ± 0.062	1.776TyrPhe: 1.776 ± 0.048	2.356TyrGly: 2.356 ± 0.053	0.68TyrHis: 0.68 ± 0.034	2.547TyrIle: 2.547 ± 0.066	2.561TyrLys: 2.561 ± 0.054	3.605TyrLeu: 3.605 ± 0.077	0.872TyrMet: 0.872 ± 0.04	1.752TyrAsn: 1.752 ± 0.039	1.293TyrPro: 1.293 ± 0.041	1.219TyrGln: 1.219 ± 0.036	1.659TyrArg: 1.659 ± 0.044	2.595TyrSer: 2.595 ± 0.058	1.92TyrThr: 1.92 ± 0.058	2.386TyrVal: 2.386 ± 0.056	0.268TyrTrp: 0.268 ± 0.021	1.447TyrTyr: 1.447 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2306 proteins (768722 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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