Amino acid dipepetide frequency for Prevotella saccharolytica F0055

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.862AlaAla: 5.862 ± 0.119	0.994AlaCys: 0.994 ± 0.04	4.53AlaAsp: 4.53 ± 0.082	4.529AlaGlu: 4.529 ± 0.083	3.552AlaPhe: 3.552 ± 0.082	4.878AlaGly: 4.878 ± 0.083	1.47AlaHis: 1.47 ± 0.044	4.522AlaIle: 4.522 ± 0.078	4.263AlaLys: 4.263 ± 0.077	6.948AlaLeu: 6.948 ± 0.1	1.931AlaMet: 1.931 ± 0.049	3.392AlaAsn: 3.392 ± 0.067	2.339AlaPro: 2.339 ± 0.05	3.274AlaGln: 3.274 ± 0.058	3.43AlaArg: 3.43 ± 0.072	4.054AlaSer: 4.054 ± 0.069	4.103AlaThr: 4.103 ± 0.078	4.863AlaVal: 4.863 ± 0.083	0.83AlaTrp: 0.83 ± 0.031	3.144AlaTyr: 3.144 ± 0.064	0.0AlaXaa: 0.0 ± 0.0
Cys	0.857CysAla: 0.857 ± 0.031	0.235CysCys: 0.235 ± 0.017	0.619CysAsp: 0.619 ± 0.028	0.637CysGlu: 0.637 ± 0.03	0.64CysPhe: 0.64 ± 0.034	0.969CysGly: 0.969 ± 0.038	0.304CysHis: 0.304 ± 0.02	0.937CysIle: 0.937 ± 0.035	0.794CysLys: 0.794 ± 0.036	1.048CysLeu: 1.048 ± 0.037	0.304CysMet: 0.304 ± 0.019	0.632CysAsn: 0.632 ± 0.026	0.46CysPro: 0.46 ± 0.025	0.362CysGln: 0.362 ± 0.023	0.622CysArg: 0.622 ± 0.029	0.712CysSer: 0.712 ± 0.029	0.722CysThr: 0.722 ± 0.029	0.768CysVal: 0.768 ± 0.035	0.168CysTrp: 0.168 ± 0.014	0.539CysTyr: 0.539 ± 0.026	0.0CysXaa: 0.0 ± 0.0
Asp	4.107AspAla: 4.107 ± 0.077	0.61AspCys: 0.61 ± 0.027	2.684AspAsp: 2.684 ± 0.065	3.626AspGlu: 3.626 ± 0.07	2.915AspPhe: 2.915 ± 0.056	4.13AspGly: 4.13 ± 0.086	0.88AspHis: 0.88 ± 0.032	4.255AspIle: 4.255 ± 0.077	3.946AspLys: 3.946 ± 0.072	4.366AspLeu: 4.366 ± 0.066	1.549AspMet: 1.549 ± 0.041	2.969AspAsn: 2.969 ± 0.056	1.751AspPro: 1.751 ± 0.045	1.188AspGln: 1.188 ± 0.037	2.455AspArg: 2.455 ± 0.059	2.894AspSer: 2.894 ± 0.061	2.946AspThr: 2.946 ± 0.064	3.667AspVal: 3.667 ± 0.069	0.766AspTrp: 0.766 ± 0.033	2.722AspTyr: 2.722 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.528GluAla: 4.528 ± 0.086	0.536GluCys: 0.536 ± 0.025	2.795GluAsp: 2.795 ± 0.061	4.106GluGlu: 4.106 ± 0.097	1.997GluPhe: 1.997 ± 0.06	3.654GluGly: 3.654 ± 0.068	1.274GluHis: 1.274 ± 0.046	3.875GluIle: 3.875 ± 0.073	4.578GluLys: 4.578 ± 0.085	5.401GluLeu: 5.401 ± 0.094	1.96GluMet: 1.96 ± 0.055	3.154GluAsn: 3.154 ± 0.06	1.685GluPro: 1.685 ± 0.049	2.734GluGln: 2.734 ± 0.065	3.431GluArg: 3.431 ± 0.065	2.595GluSer: 2.595 ± 0.051	3.283GluThr: 3.283 ± 0.067	3.765GluVal: 3.765 ± 0.068	0.742GluTrp: 0.742 ± 0.029	2.269GluTyr: 2.269 ± 0.053	0.0GluXaa: 0.0 ± 0.0
Phe	3.231PheAla: 3.231 ± 0.069	0.797PheCys: 0.797 ± 0.029	2.794PheAsp: 2.794 ± 0.058	2.332PheGlu: 2.332 ± 0.058	2.486PhePhe: 2.486 ± 0.059	3.263PheGly: 3.263 ± 0.07	0.933PheHis: 0.933 ± 0.036	3.323PheIle: 3.323 ± 0.062	2.551PheLys: 2.551 ± 0.066	4.006PheLeu: 4.006 ± 0.072	1.202PheMet: 1.202 ± 0.041	2.421PheAsn: 2.421 ± 0.054	1.648PhePro: 1.648 ± 0.041	1.225PheGln: 1.225 ± 0.033	2.035PheArg: 2.035 ± 0.056	3.565PheSer: 3.565 ± 0.067	3.078PheThr: 3.078 ± 0.069	2.951PheVal: 2.951 ± 0.057	0.581PheTrp: 0.581 ± 0.03	2.05PheTyr: 2.05 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	4.402GlyAla: 4.402 ± 0.088	0.937GlyCys: 0.937 ± 0.034	3.365GlyAsp: 3.365 ± 0.065	3.794GlyGlu: 3.794 ± 0.073	3.195GlyPhe: 3.195 ± 0.064	4.665GlyGly: 4.665 ± 0.101	1.305GlyHis: 1.305 ± 0.044	5.149GlyIle: 5.149 ± 0.084	5.121GlyLys: 5.121 ± 0.083	5.648GlyLeu: 5.648 ± 0.076	2.085GlyMet: 2.085 ± 0.049	3.636GlyAsn: 3.636 ± 0.079	1.26GlyPro: 1.26 ± 0.04	2.124GlyGln: 2.124 ± 0.048	3.27GlyArg: 3.27 ± 0.066	4.062GlySer: 4.062 ± 0.078	4.209GlyThr: 4.209 ± 0.076	4.916GlyVal: 4.916 ± 0.085	1.025GlyTrp: 1.025 ± 0.037	3.407GlyTyr: 3.407 ± 0.073	0.0GlyXaa: 0.0 ± 0.0
His	1.257HisAla: 1.257 ± 0.042	0.289HisCys: 0.289 ± 0.02	0.985HisAsp: 0.985 ± 0.033	0.997HisGlu: 0.997 ± 0.037	1.184HisPhe: 1.184 ± 0.038	1.194HisGly: 1.194 ± 0.043	0.573HisHis: 0.573 ± 0.033	1.664HisIle: 1.664 ± 0.046	0.978HisLys: 0.978 ± 0.036	2.081HisLeu: 2.081 ± 0.048	0.33HisMet: 0.33 ± 0.019	1.054HisAsn: 1.054 ± 0.039	1.106HisPro: 1.106 ± 0.042	0.755HisGln: 0.755 ± 0.032	1.1HisArg: 1.1 ± 0.036	1.171HisSer: 1.171 ± 0.037	1.323HisThr: 1.323 ± 0.042	1.012HisVal: 1.012 ± 0.032	0.284HisTrp: 0.284 ± 0.017	0.979HisTyr: 0.979 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	5.195IleAla: 5.195 ± 0.084	0.955IleCys: 0.955 ± 0.032	4.466IleAsp: 4.466 ± 0.08	4.221IleGlu: 4.221 ± 0.071	2.876IlePhe: 2.876 ± 0.054	4.687IleGly: 4.687 ± 0.093	1.29IleHis: 1.29 ± 0.04	4.453IleIle: 4.453 ± 0.083	4.246IleLys: 4.246 ± 0.068	5.603IleLeu: 5.603 ± 0.095	1.423IleMet: 1.423 ± 0.04	3.709IleAsn: 3.709 ± 0.064	2.948IlePro: 2.948 ± 0.064	2.047IleGln: 2.047 ± 0.048	3.481IleArg: 3.481 ± 0.07	4.289IleSer: 4.289 ± 0.08	4.156IleThr: 4.156 ± 0.078	4.38IleVal: 4.38 ± 0.083	0.634IleTrp: 0.634 ± 0.025	2.68IleTyr: 2.68 ± 0.061	0.0IleXaa: 0.0 ± 0.0
Lys	5.081LysAla: 5.081 ± 0.106	0.521LysCys: 0.521 ± 0.028	3.929LysAsp: 3.929 ± 0.079	4.796LysGlu: 4.796 ± 0.087	2.049LysPhe: 2.049 ± 0.055	4.513LysGly: 4.513 ± 0.077	1.344LysHis: 1.344 ± 0.046	4.073LysIle: 4.073 ± 0.064	4.927LysLys: 4.927 ± 0.081	5.235LysLeu: 5.235 ± 0.089	2.075LysMet: 2.075 ± 0.05	3.434LysAsn: 3.434 ± 0.07	2.237LysPro: 2.237 ± 0.048	2.646LysGln: 2.646 ± 0.055	3.348LysArg: 3.348 ± 0.067	3.432LysSer: 3.432 ± 0.06	4.037LysThr: 4.037 ± 0.069	4.186LysVal: 4.186 ± 0.071	0.77LysTrp: 0.77 ± 0.029	2.783LysTyr: 2.783 ± 0.061	0.0LysXaa: 0.0 ± 0.0
Leu	6.363LeuAla: 6.363 ± 0.089	1.315LeuCys: 1.315 ± 0.044	4.514LeuAsp: 4.514 ± 0.073	4.368LeuGlu: 4.368 ± 0.074	4.693LeuPhe: 4.693 ± 0.092	5.458LeuGly: 5.458 ± 0.094	2.049LeuHis: 2.049 ± 0.051	5.527LeuIle: 5.527 ± 0.096	6.045LeuLys: 6.045 ± 0.084	9.213LeuLeu: 9.213 ± 0.149	2.465LeuMet: 2.465 ± 0.056	4.898LeuAsn: 4.898 ± 0.082	4.142LeuPro: 4.142 ± 0.078	3.805LeuGln: 3.805 ± 0.084	4.49LeuArg: 4.49 ± 0.087	6.853LeuSer: 6.853 ± 0.1	5.699LeuThr: 5.699 ± 0.083	5.009LeuVal: 5.009 ± 0.082	0.999LeuTrp: 0.999 ± 0.036	3.787LeuTyr: 3.787 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	2.219MetAla: 2.219 ± 0.055	0.277MetCys: 0.277 ± 0.02	1.259MetAsp: 1.259 ± 0.045	1.455MetGlu: 1.455 ± 0.042	1.049MetPhe: 1.049 ± 0.037	1.86MetGly: 1.86 ± 0.05	0.503MetHis: 0.503 ± 0.026	1.503MetIle: 1.503 ± 0.05	2.396MetLys: 2.396 ± 0.047	2.701MetLeu: 2.701 ± 0.063	0.929MetMet: 0.929 ± 0.036	1.472MetAsn: 1.472 ± 0.037	1.217MetPro: 1.217 ± 0.041	1.238MetGln: 1.238 ± 0.038	1.429MetArg: 1.429 ± 0.043	1.575MetSer: 1.575 ± 0.037	1.369MetThr: 1.369 ± 0.039	1.64MetVal: 1.64 ± 0.053	0.252MetTrp: 0.252 ± 0.017	0.858MetTyr: 0.858 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.847AsnAla: 3.847 ± 0.079	0.499AsnCys: 0.499 ± 0.024	2.739AsnAsp: 2.739 ± 0.061	3.136AsnGlu: 3.136 ± 0.066	2.209AsnPhe: 2.209 ± 0.047	4.184AsnGly: 4.184 ± 0.085	0.981AsnHis: 0.981 ± 0.031	3.98AsnIle: 3.98 ± 0.069	3.358AsnLys: 3.358 ± 0.069	4.392AsnLeu: 4.392 ± 0.077	1.224AsnMet: 1.224 ± 0.033	2.937AsnAsn: 2.937 ± 0.072	2.266AsnPro: 2.266 ± 0.044	1.639AsnGln: 1.639 ± 0.047	2.704AsnArg: 2.704 ± 0.059	2.823AsnSer: 2.823 ± 0.059	3.056AsnThr: 3.056 ± 0.062	3.252AsnVal: 3.252 ± 0.062	0.641AsnTrp: 0.641 ± 0.03	2.352AsnTyr: 2.352 ± 0.054	0.0AsnXaa: 0.0 ± 0.0
Pro	2.628ProAla: 2.628 ± 0.063	0.348ProCys: 0.348 ± 0.021	2.373ProAsp: 2.373 ± 0.056	2.644ProGlu: 2.644 ± 0.061	1.908ProPhe: 1.908 ± 0.055	2.28ProGly: 2.28 ± 0.053	0.853ProHis: 0.853 ± 0.032	2.425ProIle: 2.425 ± 0.065	2.109ProLys: 2.109 ± 0.048	3.324ProLeu: 3.324 ± 0.066	1.034ProMet: 1.034 ± 0.032	1.835ProAsn: 1.835 ± 0.054	0.877ProPro: 0.877 ± 0.033	1.659ProGln: 1.659 ± 0.05	1.414ProArg: 1.414 ± 0.05	2.16ProSer: 2.16 ± 0.05	2.371ProThr: 2.371 ± 0.054	2.703ProVal: 2.703 ± 0.059	0.36ProTrp: 0.36 ± 0.022	1.757ProTyr: 1.757 ± 0.046	0.0ProXaa: 0.0 ± 0.0
Gln	2.652GlnAla: 2.652 ± 0.061	0.361GlnCys: 0.361 ± 0.019	1.533GlnAsp: 1.533 ± 0.045	1.991GlnGlu: 1.991 ± 0.054	1.387GlnPhe: 1.387 ± 0.039	2.109GlnGly: 2.109 ± 0.046	0.812GlnHis: 0.812 ± 0.033	2.418GlnIle: 2.418 ± 0.057	2.557GlnLys: 2.557 ± 0.062	3.939GlnLeu: 3.939 ± 0.082	1.129GlnMet: 1.129 ± 0.034	1.901GlnAsn: 1.901 ± 0.048	1.556GlnPro: 1.556 ± 0.046	1.924GlnGln: 1.924 ± 0.053	2.083GlnArg: 2.083 ± 0.051	1.981GlnSer: 1.981 ± 0.052	2.514GlnThr: 2.514 ± 0.054	2.058GlnVal: 2.058 ± 0.05	0.554GlnTrp: 0.554 ± 0.023	1.51GlnTyr: 1.51 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	3.003ArgAla: 3.003 ± 0.062	0.554ArgCys: 0.554 ± 0.026	2.195ArgAsp: 2.195 ± 0.052	2.781ArgGlu: 2.781 ± 0.063	2.504ArgPhe: 2.504 ± 0.056	2.731ArgGly: 2.731 ± 0.066	1.102ArgHis: 1.102 ± 0.038	3.639ArgIle: 3.639 ± 0.066	3.463ArgLys: 3.463 ± 0.074	4.97ArgLeu: 4.97 ± 0.083	1.625ArgMet: 1.625 ± 0.043	2.667ArgAsn: 2.667 ± 0.055	1.709ArgPro: 1.709 ± 0.047	2.071ArgGln: 2.071 ± 0.056	2.67ArgArg: 2.67 ± 0.064	2.576ArgSer: 2.576 ± 0.062	2.728ArgThr: 2.728 ± 0.054	2.843ArgVal: 2.843 ± 0.057	0.768ArgTrp: 0.768 ± 0.031	2.607ArgTyr: 2.607 ± 0.055	0.0ArgXaa: 0.0 ± 0.0
Ser	4.484SerAla: 4.484 ± 0.084	0.784SerCys: 0.784 ± 0.034	3.145SerAsp: 3.145 ± 0.066	3.159SerGlu: 3.159 ± 0.062	3.063SerPhe: 3.063 ± 0.065	4.351SerGly: 4.351 ± 0.086	1.141SerHis: 1.141 ± 0.037	4.27SerIle: 4.27 ± 0.084	3.458SerLys: 3.458 ± 0.066	5.726SerLeu: 5.726 ± 0.083	1.524SerMet: 1.524 ± 0.048	2.747SerAsn: 2.747 ± 0.066	2.365SerPro: 2.365 ± 0.049	1.841SerGln: 1.841 ± 0.045	2.574SerArg: 2.574 ± 0.058	3.76SerSer: 3.76 ± 0.074	3.529SerThr: 3.529 ± 0.071	4.255SerVal: 4.255 ± 0.08	0.71SerTrp: 0.71 ± 0.035	2.714SerTyr: 2.714 ± 0.064	0.0SerXaa: 0.0 ± 0.0
Thr	4.611ThrAla: 4.611 ± 0.078	0.628ThrCys: 0.628 ± 0.03	3.778ThrAsp: 3.778 ± 0.066	3.27ThrGlu: 3.27 ± 0.065	3.071ThrPhe: 3.071 ± 0.069	4.43ThrGly: 4.43 ± 0.075	1.214ThrHis: 1.214 ± 0.041	3.957ThrIle: 3.957 ± 0.074	2.981ThrLys: 2.981 ± 0.056	5.974ThrLeu: 5.974 ± 0.091	1.331ThrMet: 1.331 ± 0.044	2.697ThrAsn: 2.697 ± 0.062	2.922ThrPro: 2.922 ± 0.066	2.045ThrGln: 2.045 ± 0.044	2.533ThrArg: 2.533 ± 0.059	3.365ThrSer: 3.365 ± 0.076	3.741ThrThr: 3.741 ± 0.077	3.965ThrVal: 3.965 ± 0.085	0.696ThrTrp: 0.696 ± 0.034	2.703ThrTyr: 2.703 ± 0.062	0.0ThrXaa: 0.0 ± 0.0
Val	4.499ValAla: 4.499 ± 0.077	0.981ValCys: 0.981 ± 0.035	3.581ValAsp: 3.581 ± 0.069	3.696ValGlu: 3.696 ± 0.073	2.979ValPhe: 2.979 ± 0.063	4.284ValGly: 4.284 ± 0.082	1.068ValHis: 1.068 ± 0.038	4.144ValIle: 4.144 ± 0.08	4.228ValLys: 4.228 ± 0.077	5.907ValLeu: 5.907 ± 0.089	1.663ValMet: 1.663 ± 0.048	3.38ValAsn: 3.38 ± 0.063	2.453ValPro: 2.453 ± 0.059	2.088ValGln: 2.088 ± 0.053	3.039ValArg: 3.039 ± 0.059	4.448ValSer: 4.448 ± 0.086	3.599ValThr: 3.599 ± 0.078	4.65ValVal: 4.65 ± 0.086	0.767ValTrp: 0.767 ± 0.03	2.685ValTyr: 2.685 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.886TrpAla: 0.886 ± 0.036	0.17TrpCys: 0.17 ± 0.014	0.635TrpAsp: 0.635 ± 0.029	0.629TrpGlu: 0.629 ± 0.03	0.548TrpPhe: 0.548 ± 0.025	0.976TrpGly: 0.976 ± 0.035	0.269TrpHis: 0.269 ± 0.018	0.743TrpIle: 0.743 ± 0.029	0.838TrpLys: 0.838 ± 0.032	1.2TrpLeu: 1.2 ± 0.041	0.43TrpMet: 0.43 ± 0.025	0.734TrpAsn: 0.734 ± 0.032	0.27TrpPro: 0.27 ± 0.019	0.62TrpGln: 0.62 ± 0.026	0.646TrpArg: 0.646 ± 0.031	0.655TrpSer: 0.655 ± 0.036	0.658TrpThr: 0.658 ± 0.027	0.731TrpVal: 0.731 ± 0.029	0.183TrpTrp: 0.183 ± 0.015	0.495TrpTyr: 0.495 ± 0.029	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.195TyrAla: 3.195 ± 0.063	0.538TyrCys: 0.538 ± 0.028	2.505TyrAsp: 2.505 ± 0.064	2.197TyrGlu: 2.197 ± 0.05	2.168TyrPhe: 2.168 ± 0.054	2.96TyrGly: 2.96 ± 0.069	0.954TyrHis: 0.954 ± 0.037	2.882TyrIle: 2.882 ± 0.062	2.581TyrLys: 2.581 ± 0.053	4.009TyrLeu: 4.009 ± 0.071	0.988TyrMet: 0.988 ± 0.038	2.546TyrAsn: 2.546 ± 0.054	1.853TyrPro: 1.853 ± 0.041	1.683TyrGln: 1.683 ± 0.051	2.453TyrArg: 2.453 ± 0.045	2.63TyrSer: 2.63 ± 0.069	2.794TyrThr: 2.794 ± 0.063	2.521TyrVal: 2.521 ± 0.055	0.586TyrTrp: 0.586 ± 0.03	2.092TyrTyr: 2.092 ± 0.059	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2553 proteins (834224 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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