Amino acid dipepetide frequency for Alternanthera mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.97AlaAla: 6.97 ± 6.038
0.929AlaCys: 0.929 ± 0.868
2.788AlaAsp: 2.788 ± 0.805
5.112AlaGlu: 5.112 ± 1.069
6.506AlaPhe: 6.506 ± 1.398
5.112AlaGly: 5.112 ± 1.595
0.929AlaHis: 0.929 ± 0.45
3.253AlaIle: 3.253 ± 1.129
4.647AlaLys: 4.647 ± 1.483
10.688AlaLeu: 10.688 ± 3.922
3.253AlaMet: 3.253 ± 0.904
4.647AlaAsn: 4.647 ± 2.694
5.112AlaPro: 5.112 ± 0.723
2.788AlaGln: 2.788 ± 0.86
3.253AlaArg: 3.253 ± 0.789
4.647AlaSer: 4.647 ± 3.097
4.647AlaThr: 4.647 ± 1.452
2.323AlaVal: 2.323 ± 0.881
1.394AlaTrp: 1.394 ± 0.675
2.323AlaTyr: 2.323 ± 0.725
0.0AlaXaa: 0.0 ± 0.0
Cys
0.465CysAla: 0.465 ± 0.744
0.465CysCys: 0.465 ± 0.94
0.465CysAsp: 0.465 ± 0.225
0.929CysGlu: 0.929 ± 0.628
0.465CysPhe: 0.465 ± 0.225
1.859CysGly: 1.859 ± 0.811
0.929CysHis: 0.929 ± 0.45
0.929CysIle: 0.929 ± 0.868
0.465CysLys: 0.465 ± 0.225
0.465CysLeu: 0.465 ± 0.225
0.0CysMet: 0.0 ± 0.0
0.465CysAsn: 0.465 ± 0.225
1.394CysPro: 1.394 ± 1.156
0.465CysGln: 0.465 ± 0.225
0.929CysArg: 0.929 ± 1.489
1.859CysSer: 1.859 ± 0.723
0.929CysThr: 0.929 ± 0.868
0.465CysVal: 0.465 ± 0.225
0.0CysTrp: 0.0 ± 0.0
0.929CysTyr: 0.929 ± 0.735
0.0CysXaa: 0.0 ± 0.0
Asp
1.859AspAla: 1.859 ± 0.901
0.465AspCys: 0.465 ± 0.976
0.929AspAsp: 0.929 ± 0.45
2.788AspGlu: 2.788 ± 0.878
0.929AspPhe: 0.929 ± 0.735
2.323AspGly: 2.323 ± 0.978
0.929AspHis: 0.929 ± 0.814
0.465AspIle: 0.465 ± 0.225
1.394AspLys: 1.394 ± 0.627
3.717AspLeu: 3.717 ± 1.801
0.465AspMet: 0.465 ± 0.225
3.253AspAsn: 3.253 ± 1.565
5.112AspPro: 5.112 ± 1.786
3.253AspGln: 3.253 ± 1.058
0.465AspArg: 0.465 ± 0.225
3.717AspSer: 3.717 ± 1.233
2.323AspThr: 2.323 ± 1.188
3.717AspVal: 3.717 ± 1.801
1.859AspTrp: 1.859 ± 0.901
1.859AspTyr: 1.859 ± 0.811
0.0AspXaa: 0.0 ± 0.0
Glu
5.576GluAla: 5.576 ± 1.459
0.465GluCys: 0.465 ± 0.225
4.647GluAsp: 4.647 ± 1.665
5.112GluGlu: 5.112 ± 1.595
3.253GluPhe: 3.253 ± 1.058
2.323GluGly: 2.323 ± 1.981
0.465GluHis: 0.465 ± 0.225
3.253GluIle: 3.253 ± 1.058
5.576GluLys: 5.576 ± 1.905
6.506GluLeu: 6.506 ± 1.624
0.929GluMet: 0.929 ± 0.508
2.323GluAsn: 2.323 ± 0.634
3.717GluPro: 3.717 ± 1.252
1.859GluGln: 1.859 ± 1.469
1.859GluArg: 1.859 ± 0.589
4.647GluSer: 4.647 ± 1.665
4.647GluThr: 4.647 ± 1.1
3.253GluVal: 3.253 ± 1.071
1.394GluTrp: 1.394 ± 0.675
0.929GluTyr: 0.929 ± 0.628
0.0GluXaa: 0.0 ± 0.0
Phe
2.323PheAla: 2.323 ± 2.346
1.394PheCys: 1.394 ± 1.614
3.253PheAsp: 3.253 ± 1.195
3.253PheGlu: 3.253 ± 1.176
1.859PhePhe: 1.859 ± 1.469
3.253PheGly: 3.253 ± 0.789
2.323PheHis: 2.323 ± 1.126
3.253PheIle: 3.253 ± 1.938
3.253PheLys: 3.253 ± 1.071
5.576PheLeu: 5.576 ± 1.775
1.394PheMet: 1.394 ± 0.708
0.929PheAsn: 0.929 ± 0.628
1.394PhePro: 1.394 ± 0.627
2.323PheGln: 2.323 ± 0.634
1.859PheArg: 1.859 ± 0.901
3.717PheSer: 3.717 ± 1.801
2.323PheThr: 2.323 ± 0.634
1.859PheVal: 1.859 ± 0.901
0.465PheTrp: 0.465 ± 0.225
0.929PheTyr: 0.929 ± 0.45
0.0PheXaa: 0.0 ± 0.0
Gly
6.041GlyAla: 6.041 ± 1.379
0.465GlyCys: 0.465 ± 0.225
5.112GlyAsp: 5.112 ± 1.715
1.394GlyGlu: 1.394 ± 0.675
2.323GlyPhe: 2.323 ± 0.634
4.182GlyGly: 4.182 ± 1.472
2.788GlyHis: 2.788 ± 1.072
1.859GlyIle: 1.859 ± 1.256
3.253GlyLys: 3.253 ± 1.058
3.253GlyLeu: 3.253 ± 1.751
0.0GlyMet: 0.0 ± 0.0
1.859GlyAsn: 1.859 ± 0.901
3.717GlyPro: 3.717 ± 0.908
2.323GlyGln: 2.323 ± 0.634
0.929GlyArg: 0.929 ± 0.628
4.647GlySer: 4.647 ± 1.731
5.112GlyThr: 5.112 ± 0.439
3.253GlyVal: 3.253 ± 1.751
0.465GlyTrp: 0.465 ± 0.225
2.323GlyTyr: 2.323 ± 0.725
0.0GlyXaa: 0.0 ± 0.0
His
3.253HisAla: 3.253 ± 1.071
0.465HisCys: 0.465 ± 0.225
0.465HisAsp: 0.465 ± 0.225
3.253HisGlu: 3.253 ± 1.576
2.788HisPhe: 2.788 ± 1.161
2.788HisGly: 2.788 ± 1.161
1.394HisHis: 1.394 ± 0.736
0.929HisIle: 0.929 ± 0.45
0.929HisLys: 0.929 ± 0.45
1.859HisLeu: 1.859 ± 0.901
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.859HisPro: 1.859 ± 0.964
2.323HisGln: 2.323 ± 0.881
4.647HisArg: 4.647 ± 2.427
4.182HisSer: 4.182 ± 1.652
1.394HisThr: 1.394 ± 0.675
0.929HisVal: 0.929 ± 0.628
0.0HisTrp: 0.0 ± 0.0
1.859HisTyr: 1.859 ± 1.003
0.0HisXaa: 0.0 ± 0.0
Ile
5.576IleAla: 5.576 ± 2.383
0.0IleCys: 0.0 ± 0.0
0.465IleAsp: 0.465 ± 0.225
3.717IleGlu: 3.717 ± 1.252
4.182IlePhe: 4.182 ± 1.456
1.859IleGly: 1.859 ± 0.811
3.253IleHis: 3.253 ± 1.594
1.394IleIle: 1.394 ± 1.302
5.112IleLys: 5.112 ± 1.595
4.182IleLeu: 4.182 ± 2.333
0.465IleMet: 0.465 ± 0.225
3.253IleAsn: 3.253 ± 0.789
2.323IlePro: 2.323 ± 1.126
3.253IleGln: 3.253 ± 0.41
1.859IleArg: 1.859 ± 0.964
3.717IleSer: 3.717 ± 1.028
4.182IleThr: 4.182 ± 1.57
1.859IleVal: 1.859 ± 0.589
0.929IleTrp: 0.929 ± 0.735
2.323IleTyr: 2.323 ± 0.777
0.0IleXaa: 0.0 ± 0.0
Lys
4.647LysAla: 4.647 ± 1.483
0.465LysCys: 0.465 ± 0.225
2.788LysAsp: 2.788 ± 1.351
1.859LysGlu: 1.859 ± 0.901
3.253LysPhe: 3.253 ± 1.222
3.253LysGly: 3.253 ± 0.904
3.253LysHis: 3.253 ± 1.176
2.323LysIle: 2.323 ± 1.126
5.576LysLys: 5.576 ± 2.702
6.506LysLeu: 6.506 ± 3.152
0.929LysMet: 0.929 ± 0.45
2.323LysAsn: 2.323 ± 0.725
5.112LysPro: 5.112 ± 1.083
2.323LysGln: 2.323 ± 0.634
1.394LysArg: 1.394 ± 0.58
4.182LysSer: 4.182 ± 1.195
5.576LysThr: 5.576 ± 1.194
2.323LysVal: 2.323 ± 0.634
0.0LysTrp: 0.0 ± 0.0
2.323LysTyr: 2.323 ± 1.126
0.0LysXaa: 0.0 ± 0.0
Leu
6.97LeuAla: 6.97 ± 2.201
0.465LeuCys: 0.465 ± 0.744
5.112LeuAsp: 5.112 ± 1.595
5.112LeuGlu: 5.112 ± 0.985
5.112LeuPhe: 5.112 ± 0.985
4.182LeuGly: 4.182 ± 1.119
4.647LeuHis: 4.647 ± 1.073
5.576LeuIle: 5.576 ± 3.709
6.506LeuLys: 6.506 ± 3.152
7.435LeuLeu: 7.435 ± 1.432
0.929LeuMet: 0.929 ± 0.547
0.929LeuAsn: 0.929 ± 0.45
9.294LeuPro: 9.294 ± 1.917
3.717LeuGln: 3.717 ± 1.252
6.97LeuArg: 6.97 ± 1.801
8.364LeuSer: 8.364 ± 2.536
6.97LeuThr: 6.97 ± 1.778
7.435LeuVal: 7.435 ± 2.668
0.929LeuTrp: 0.929 ± 0.45
2.788LeuTyr: 2.788 ± 0.878
0.0LeuXaa: 0.0 ± 0.0
Met
0.929MetAla: 0.929 ± 0.45
0.465MetCys: 0.465 ± 0.225
0.0MetAsp: 0.0 ± 0.0
1.394MetGlu: 1.394 ± 0.675
0.929MetPhe: 0.929 ± 0.45
0.929MetGly: 0.929 ± 0.45
0.929MetHis: 0.929 ± 0.45
0.465MetIle: 0.465 ± 0.225
0.465MetLys: 0.465 ± 0.225
1.859MetLeu: 1.859 ± 0.901
0.0MetMet: 0.0 ± 0.0
1.394MetAsn: 1.394 ± 0.994
1.394MetPro: 1.394 ± 0.809
0.929MetGln: 0.929 ± 0.735
1.394MetArg: 1.394 ± 0.675
1.859MetSer: 1.859 ± 1.129
0.465MetThr: 0.465 ± 0.225
0.465MetVal: 0.465 ± 0.225
0.0MetTrp: 0.0 ± 0.0
0.929MetTyr: 0.929 ± 0.45
0.0MetXaa: 0.0 ± 0.0
Asn
2.788AsnAla: 2.788 ± 1.253
1.394AsnCys: 1.394 ± 0.675
1.394AsnAsp: 1.394 ± 0.675
1.859AsnGlu: 1.859 ± 0.617
1.859AsnPhe: 1.859 ± 1.469
2.323AsnGly: 2.323 ± 1.347
1.859AsnHis: 1.859 ± 1.256
2.323AsnIle: 2.323 ± 1.358
1.859AsnLys: 1.859 ± 0.794
4.182AsnLeu: 4.182 ± 2.341
0.929AsnMet: 0.929 ± 0.45
1.394AsnAsn: 1.394 ± 0.627
4.647AsnPro: 4.647 ± 0.786
1.859AsnGln: 1.859 ± 0.901
0.465AsnArg: 0.465 ± 0.225
3.717AsnSer: 3.717 ± 2.258
0.465AsnThr: 0.465 ± 0.225
1.394AsnVal: 1.394 ± 0.58
0.929AsnTrp: 0.929 ± 0.735
0.465AsnTyr: 0.465 ± 0.225
0.0AsnXaa: 0.0 ± 0.0
Pro
6.041ProAla: 6.041 ± 1.734
1.859ProCys: 1.859 ± 1.26
2.788ProAsp: 2.788 ± 1.884
4.182ProGlu: 4.182 ± 1.092
3.253ProPhe: 3.253 ± 1.686
3.717ProGly: 3.717 ± 1.316
2.323ProHis: 2.323 ± 1.358
5.576ProIle: 5.576 ± 1.905
6.041ProLys: 6.041 ± 2.927
4.182ProLeu: 4.182 ± 4.075
0.0ProMet: 0.0 ± 0.0
2.788ProAsn: 2.788 ± 1.161
6.97ProPro: 6.97 ± 2.74
2.788ProGln: 2.788 ± 0.47
1.394ProArg: 1.394 ± 1.156
5.576ProSer: 5.576 ± 1.868
5.576ProThr: 5.576 ± 1.496
3.253ProVal: 3.253 ± 1.155
0.465ProTrp: 0.465 ± 0.225
1.859ProTyr: 1.859 ± 0.811
0.0ProXaa: 0.0 ± 0.0
Gln
6.041GlnAla: 6.041 ± 1.478
0.465GlnCys: 0.465 ± 0.225
1.394GlnAsp: 1.394 ± 0.627
3.253GlnGlu: 3.253 ± 0.904
0.929GlnPhe: 0.929 ± 0.45
2.323GlnGly: 2.323 ± 0.725
1.859GlnHis: 1.859 ± 1.256
4.182GlnIle: 4.182 ± 0.834
2.323GlnLys: 2.323 ± 1.126
4.647GlnLeu: 4.647 ± 1.228
2.323GlnMet: 2.323 ± 0.634
0.0GlnAsn: 0.0 ± 0.0
1.394GlnPro: 1.394 ± 0.627
1.859GlnGln: 1.859 ± 0.901
1.859GlnArg: 1.859 ± 0.901
2.788GlnSer: 2.788 ± 0.887
1.394GlnThr: 1.394 ± 0.675
2.323GlnVal: 2.323 ± 2.195
1.394GlnTrp: 1.394 ± 0.675
1.859GlnTyr: 1.859 ± 0.589
0.0GlnXaa: 0.0 ± 0.0
Arg
5.576ArgAla: 5.576 ± 2.517
0.465ArgCys: 0.465 ± 0.94
2.323ArgAsp: 2.323 ± 0.777
4.647ArgGlu: 4.647 ± 1.665
2.323ArgPhe: 2.323 ± 2.083
2.788ArgGly: 2.788 ± 0.887
0.465ArgHis: 0.465 ± 0.744
1.394ArgIle: 1.394 ± 0.627
1.394ArgLys: 1.394 ± 1.792
4.182ArgLeu: 4.182 ± 1.429
0.929ArgMet: 0.929 ± 0.45
1.859ArgAsn: 1.859 ± 0.901
1.394ArgPro: 1.394 ± 1.112
1.859ArgGln: 1.859 ± 0.901
0.929ArgArg: 0.929 ± 0.628
3.717ArgSer: 3.717 ± 1.233
2.788ArgThr: 2.788 ± 1.395
2.323ArgVal: 2.323 ± 0.725
0.0ArgTrp: 0.0 ± 0.0
1.859ArgTyr: 1.859 ± 0.901
0.0ArgXaa: 0.0 ± 0.0
Ser
4.647SerAla: 4.647 ± 1.142
2.323SerCys: 2.323 ± 0.777
1.394SerAsp: 1.394 ± 0.58
4.182SerGlu: 4.182 ± 0.85
1.859SerPhe: 1.859 ± 0.723
4.182SerGly: 4.182 ± 2.327
2.788SerHis: 2.788 ± 0.786
5.112SerIle: 5.112 ± 1.796
2.788SerLys: 2.788 ± 0.887
11.152SerLeu: 11.152 ± 1.802
0.929SerMet: 0.929 ± 0.727
3.717SerAsn: 3.717 ± 2.084
5.576SerPro: 5.576 ± 2.284
6.041SerGln: 6.041 ± 1.924
3.253SerArg: 3.253 ± 1.576
5.112SerSer: 5.112 ± 2.592
5.112SerThr: 5.112 ± 1.964
3.253SerVal: 3.253 ± 1.576
0.465SerTrp: 0.465 ± 0.744
3.253SerTyr: 3.253 ± 1.035
0.0SerXaa: 0.0 ± 0.0
Thr
2.788ThrAla: 2.788 ± 1.351
0.929ThrCys: 0.929 ± 0.628
1.394ThrAsp: 1.394 ± 0.627
4.647ThrGlu: 4.647 ± 0.786
4.182ThrPhe: 4.182 ± 2.026
4.647ThrGly: 4.647 ± 1.747
2.788ThrHis: 2.788 ± 0.878
5.112ThrIle: 5.112 ± 4.003
3.253ThrLys: 3.253 ± 0.789
5.112ThrLeu: 5.112 ± 1.595
0.929ThrMet: 0.929 ± 0.45
2.323ThrAsn: 2.323 ± 0.613
6.97ThrPro: 6.97 ± 2.442
1.394ThrGln: 1.394 ± 0.627
1.859ThrArg: 1.859 ± 1.256
3.253ThrSer: 3.253 ± 1.195
1.859ThrThr: 1.859 ± 2.822
5.576ThrVal: 5.576 ± 1.582
0.0ThrTrp: 0.0 ± 0.0
2.323ThrTyr: 2.323 ± 0.634
0.0ThrXaa: 0.0 ± 0.0
Val
3.717ValAla: 3.717 ± 1.793
0.0ValCys: 0.0 ± 0.0
2.323ValAsp: 2.323 ± 0.725
3.717ValGlu: 3.717 ± 1.04
0.465ValPhe: 0.465 ± 0.225
2.323ValGly: 2.323 ± 1.358
1.394ValHis: 1.394 ± 0.58
3.253ValIle: 3.253 ± 0.789
3.253ValLys: 3.253 ± 0.904
8.364ValLeu: 8.364 ± 1.778
0.929ValMet: 0.929 ± 0.45
2.323ValAsn: 2.323 ± 1.347
2.323ValPro: 2.323 ± 1.406
1.394ValGln: 1.394 ± 0.675
4.647ValArg: 4.647 ± 2.375
3.253ValSer: 3.253 ± 0.942
3.717ValThr: 3.717 ± 1.801
3.253ValVal: 3.253 ± 2.457
0.0ValTrp: 0.0 ± 0.0
0.929ValTyr: 0.929 ± 0.814
0.0ValXaa: 0.0 ± 0.0
Trp
2.323TrpAla: 2.323 ± 1.126
0.465TrpCys: 0.465 ± 0.225
0.0TrpAsp: 0.0 ± 0.0
0.929TrpGlu: 0.929 ± 0.735
0.0TrpPhe: 0.0 ± 0.0
0.465TrpGly: 0.465 ± 0.225
0.0TrpHis: 0.0 ± 0.0
0.465TrpIle: 0.465 ± 0.225
0.929TrpLys: 0.929 ± 0.45
1.859TrpLeu: 1.859 ± 0.901
0.0TrpMet: 0.0 ± 0.0
0.929TrpAsn: 0.929 ± 1.203
0.465TrpPro: 0.465 ± 0.225
0.465TrpGln: 0.465 ± 0.225
0.0TrpArg: 0.0 ± 0.0
0.465TrpSer: 0.465 ± 0.225
0.0TrpThr: 0.0 ± 0.0
0.929TrpVal: 0.929 ± 0.45
0.465TrpTrp: 0.465 ± 0.225
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.788TyrAla: 2.788 ± 0.887
0.929TyrCys: 0.929 ± 0.628
2.788TyrAsp: 2.788 ± 0.748
1.859TyrGlu: 1.859 ± 0.901
0.465TyrPhe: 0.465 ± 0.225
0.465TyrGly: 0.465 ± 0.225
0.0TyrHis: 0.0 ± 0.0
2.788TyrIle: 2.788 ± 1.161
1.394TyrLys: 1.394 ± 0.675
3.717TyrLeu: 3.717 ± 1.87
1.394TyrMet: 1.394 ± 0.634
1.394TyrAsn: 1.394 ± 0.736
0.465TyrPro: 0.465 ± 0.225
1.394TyrGln: 1.394 ± 0.675
3.253TyrArg: 3.253 ± 1.441
3.717TyrSer: 3.717 ± 1.801
1.859TyrThr: 1.859 ± 0.794
1.394TyrVal: 1.394 ± 0.58
0.0TyrTrp: 0.0 ± 0.0
0.929TyrTyr: 0.929 ± 0.45
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2153 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski