Amino acid dipepetide frequency for Trinickia fusca

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.443AlaAla: 17.443 ± 0.178
1.381AlaCys: 1.381 ± 0.03
6.559AlaAsp: 6.559 ± 0.064
5.973AlaGlu: 5.973 ± 0.078
4.311AlaPhe: 4.311 ± 0.051
10.454AlaGly: 10.454 ± 0.134
3.074AlaHis: 3.074 ± 0.047
5.525AlaIle: 5.525 ± 0.054
3.7AlaLys: 3.7 ± 0.063
14.769AlaLeu: 14.769 ± 0.127
3.119AlaMet: 3.119 ± 0.047
3.563AlaAsn: 3.563 ± 0.073
6.144AlaPro: 6.144 ± 0.087
5.945AlaGln: 5.945 ± 0.077
9.144AlaArg: 9.144 ± 0.111
8.0AlaSer: 8.0 ± 0.079
6.805AlaThr: 6.805 ± 0.086
8.645AlaVal: 8.645 ± 0.073
1.704AlaTrp: 1.704 ± 0.037
2.888AlaTyr: 2.888 ± 0.05
0.0AlaXaa: 0.0 ± 0.0
Cys
1.299CysAla: 1.299 ± 0.031
0.117CysCys: 0.117 ± 0.008
0.544CysAsp: 0.544 ± 0.019
0.508CysGlu: 0.508 ± 0.018
0.31CysPhe: 0.31 ± 0.014
0.976CysGly: 0.976 ± 0.025
0.243CysHis: 0.243 ± 0.012
0.382CysIle: 0.382 ± 0.014
0.219CysLys: 0.219 ± 0.013
0.802CysLeu: 0.802 ± 0.023
0.179CysMet: 0.179 ± 0.01
0.223CysAsn: 0.223 ± 0.012
0.469CysPro: 0.469 ± 0.018
0.222CysGln: 0.222 ± 0.013
0.611CysArg: 0.611 ± 0.018
0.545CysSer: 0.545 ± 0.019
0.493CysThr: 0.493 ± 0.019
0.772CysVal: 0.772 ± 0.021
0.106CysTrp: 0.106 ± 0.008
0.23CysTyr: 0.23 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
8.053AspAla: 8.053 ± 0.096
0.483AspCys: 0.483 ± 0.019
3.134AspAsp: 3.134 ± 0.047
3.601AspGlu: 3.601 ± 0.054
1.906AspPhe: 1.906 ± 0.037
4.708AspGly: 4.708 ± 0.062
1.086AspHis: 1.086 ± 0.027
2.461AspIle: 2.461 ± 0.039
1.523AspLys: 1.523 ± 0.029
4.984AspLeu: 4.984 ± 0.055
1.139AspMet: 1.139 ± 0.029
1.289AspAsn: 1.289 ± 0.032
2.775AspPro: 2.775 ± 0.047
1.588AspGln: 1.588 ± 0.036
3.155AspArg: 3.155 ± 0.048
2.528AspSer: 2.528 ± 0.048
3.048AspThr: 3.048 ± 0.055
4.445AspVal: 4.445 ± 0.053
0.935AspTrp: 0.935 ± 0.024
1.563AspTyr: 1.563 ± 0.03
0.0AspXaa: 0.0 ± 0.0
Glu
6.773GluAla: 6.773 ± 0.096
0.408GluCys: 0.408 ± 0.016
2.074GluAsp: 2.074 ± 0.044
2.225GluGlu: 2.225 ± 0.051
1.725GluPhe: 1.725 ± 0.036
3.312GluGly: 3.312 ± 0.047
1.605GluHis: 1.605 ± 0.036
2.609GluIle: 2.609 ± 0.046
1.635GluLys: 1.635 ± 0.038
5.445GluLeu: 5.445 ± 0.076
1.091GluMet: 1.091 ± 0.03
1.326GluAsn: 1.326 ± 0.03
2.722GluPro: 2.722 ± 0.053
2.565GluGln: 2.565 ± 0.046
5.184GluArg: 5.184 ± 0.076
2.629GluSer: 2.629 ± 0.044
2.847GluThr: 2.847 ± 0.045
3.467GluVal: 3.467 ± 0.049
0.706GluTrp: 0.706 ± 0.023
1.23GluTyr: 1.23 ± 0.025
0.0GluXaa: 0.0 ± 0.0
Phe
4.687PheAla: 4.687 ± 0.056
0.406PheCys: 0.406 ± 0.017
2.665PheAsp: 2.665 ± 0.038
2.103PheGlu: 2.103 ± 0.039
1.328PhePhe: 1.328 ± 0.033
3.51PheGly: 3.51 ± 0.047
0.756PheHis: 0.756 ± 0.022
1.456PheIle: 1.456 ± 0.028
1.043PheLys: 1.043 ± 0.027
2.798PheLeu: 2.798 ± 0.05
0.733PheMet: 0.733 ± 0.02
1.066PheAsn: 1.066 ± 0.027
1.425PhePro: 1.425 ± 0.031
0.927PheGln: 0.927 ± 0.024
1.823PheArg: 1.823 ± 0.035
2.254PheSer: 2.254 ± 0.037
1.954PheThr: 1.954 ± 0.05
3.202PheVal: 3.202 ± 0.047
0.45PheTrp: 0.45 ± 0.016
0.931PheTyr: 0.931 ± 0.028
0.0PheXaa: 0.0 ± 0.0
Gly
9.328GlyAla: 9.328 ± 0.1
0.819GlyCys: 0.819 ± 0.022
4.107GlyAsp: 4.107 ± 0.06
4.243GlyGlu: 4.243 ± 0.06
3.133GlyPhe: 3.133 ± 0.045
6.817GlyGly: 6.817 ± 0.136
1.974GlyHis: 1.974 ± 0.04
4.057GlyIle: 4.057 ± 0.057
3.056GlyLys: 3.056 ± 0.047
7.657GlyLeu: 7.657 ± 0.077
2.09GlyMet: 2.09 ± 0.04
2.786GlyAsn: 2.786 ± 0.105
2.854GlyPro: 2.854 ± 0.044
2.94GlyGln: 2.94 ± 0.056
5.014GlyArg: 5.014 ± 0.059
4.972GlySer: 4.972 ± 0.094
5.101GlyThr: 5.101 ± 0.111
6.41GlyVal: 6.41 ± 0.069
1.26GlyTrp: 1.26 ± 0.027
2.477GlyTyr: 2.477 ± 0.048
0.0GlyXaa: 0.0 ± 0.0
His
3.239HisAla: 3.239 ± 0.049
0.273HisCys: 0.273 ± 0.013
1.406HisAsp: 1.406 ± 0.03
1.341HisGlu: 1.341 ± 0.033
0.924HisPhe: 0.924 ± 0.026
2.198HisGly: 2.198 ± 0.036
0.682HisHis: 0.682 ± 0.025
0.926HisIle: 0.926 ± 0.026
0.495HisLys: 0.495 ± 0.018
2.191HisLeu: 2.191 ± 0.041
0.51HisMet: 0.51 ± 0.018
0.537HisAsn: 0.537 ± 0.02
1.421HisPro: 1.421 ± 0.029
0.621HisGln: 0.621 ± 0.02
1.603HisArg: 1.603 ± 0.031
1.12HisSer: 1.12 ± 0.023
1.175HisThr: 1.175 ± 0.028
1.875HisVal: 1.875 ± 0.033
0.436HisTrp: 0.436 ± 0.017
0.691HisTyr: 0.691 ± 0.021
0.0HisXaa: 0.0 ± 0.0
Ile
6.756IleAla: 6.756 ± 0.071
0.413IleCys: 0.413 ± 0.016
3.549IleAsp: 3.549 ± 0.049
3.353IleGlu: 3.353 ± 0.052
1.268IlePhe: 1.268 ± 0.029
4.512IleGly: 4.512 ± 0.055
0.849IleHis: 0.849 ± 0.021
1.332IleIle: 1.332 ± 0.029
1.311IleLys: 1.311 ± 0.033
3.06IleLeu: 3.06 ± 0.049
0.649IleMet: 0.649 ± 0.023
1.34IleAsn: 1.34 ± 0.024
1.86IlePro: 1.86 ± 0.035
1.151IleGln: 1.151 ± 0.031
2.61IleArg: 2.61 ± 0.043
2.384IleSer: 2.384 ± 0.04
2.394IleThr: 2.394 ± 0.051
4.483IleVal: 4.483 ± 0.063
0.499IleTrp: 0.499 ± 0.016
1.03IleTyr: 1.03 ± 0.027
0.0IleXaa: 0.0 ± 0.0
Lys
3.39LysAla: 3.39 ± 0.059
0.184LysCys: 0.184 ± 0.01
1.381LysAsp: 1.381 ± 0.029
1.313LysGlu: 1.313 ± 0.031
0.842LysPhe: 0.842 ± 0.023
2.002LysGly: 2.002 ± 0.041
0.737LysHis: 0.737 ± 0.022
1.448LysIle: 1.448 ± 0.029
1.086LysLys: 1.086 ± 0.04
3.256LysLeu: 3.256 ± 0.048
0.697LysMet: 0.697 ± 0.024
0.835LysAsn: 0.835 ± 0.024
1.805LysPro: 1.805 ± 0.036
1.261LysGln: 1.261 ± 0.033
2.291LysArg: 2.291 ± 0.045
1.639LysSer: 1.639 ± 0.034
1.875LysThr: 1.875 ± 0.038
2.063LysVal: 2.063 ± 0.038
0.341LysTrp: 0.341 ± 0.015
0.67LysTyr: 0.67 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
14.578LeuAla: 14.578 ± 0.13
0.954LeuCys: 0.954 ± 0.023
5.971LeuAsp: 5.971 ± 0.069
5.183LeuGlu: 5.183 ± 0.071
3.438LeuPhe: 3.438 ± 0.058
7.909LeuGly: 7.909 ± 0.078
2.271LeuHis: 2.271 ± 0.043
4.448LeuIle: 4.448 ± 0.057
3.078LeuLys: 3.078 ± 0.052
9.641LeuLeu: 9.641 ± 0.102
2.122LeuMet: 2.122 ± 0.035
2.793LeuAsn: 2.793 ± 0.05
5.758LeuPro: 5.758 ± 0.067
3.295LeuGln: 3.295 ± 0.049
7.046LeuArg: 7.046 ± 0.086
6.228LeuSer: 6.228 ± 0.08
5.99LeuThr: 5.99 ± 0.079
7.614LeuVal: 7.614 ± 0.083
1.143LeuTrp: 1.143 ± 0.026
2.195LeuTyr: 2.195 ± 0.041
0.0LeuXaa: 0.0 ± 0.0
Met
2.442MetAla: 2.442 ± 0.04
0.161MetCys: 0.161 ± 0.01
0.897MetAsp: 0.897 ± 0.025
0.819MetGlu: 0.819 ± 0.025
0.702MetPhe: 0.702 ± 0.021
1.47MetGly: 1.47 ± 0.032
0.552MetHis: 0.552 ± 0.02
0.993MetIle: 0.993 ± 0.029
0.917MetLys: 0.917 ± 0.023
2.583MetLeu: 2.583 ± 0.043
0.544MetMet: 0.544 ± 0.019
0.875MetAsn: 0.875 ± 0.02
1.467MetPro: 1.467 ± 0.031
1.04MetGln: 1.04 ± 0.028
1.797MetArg: 1.797 ± 0.035
1.734MetSer: 1.734 ± 0.034
1.586MetThr: 1.586 ± 0.032
1.322MetVal: 1.322 ± 0.025
0.196MetTrp: 0.196 ± 0.012
0.372MetTyr: 0.372 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
3.751AsnAla: 3.751 ± 0.078
0.258AsnCys: 0.258 ± 0.013
1.51AsnAsp: 1.51 ± 0.037
1.379AsnGlu: 1.379 ± 0.027
0.967AsnPhe: 0.967 ± 0.028
2.934AsnGly: 2.934 ± 0.083
0.54AsnHis: 0.54 ± 0.02
1.156AsnIle: 1.156 ± 0.027
0.665AsnLys: 0.665 ± 0.024
2.75AsnLeu: 2.75 ± 0.053
0.524AsnMet: 0.524 ± 0.018
0.91AsnAsn: 0.91 ± 0.035
1.759AsnPro: 1.759 ± 0.034
0.984AsnGln: 0.984 ± 0.034
1.753AsnArg: 1.753 ± 0.036
1.421AsnSer: 1.421 ± 0.044
1.656AsnThr: 1.656 ± 0.049
2.569AsnVal: 2.569 ± 0.062
0.463AsnTrp: 0.463 ± 0.019
0.794AsnTyr: 0.794 ± 0.024
0.0AsnXaa: 0.0 ± 0.0
Pro
6.53ProAla: 6.53 ± 0.096
0.353ProCys: 0.353 ± 0.015
3.124ProAsp: 3.124 ± 0.042
2.861ProGlu: 2.861 ± 0.051
1.898ProPhe: 1.898 ± 0.035
4.098ProGly: 4.098 ± 0.053
1.281ProHis: 1.281 ± 0.03
2.165ProIle: 2.165 ± 0.04
1.345ProLys: 1.345 ± 0.033
5.099ProLeu: 5.099 ± 0.062
1.091ProMet: 1.091 ± 0.024
1.503ProAsn: 1.503 ± 0.03
2.544ProPro: 2.544 ± 0.055
1.941ProGln: 1.941 ± 0.037
2.904ProArg: 2.904 ± 0.053
3.11ProSer: 3.11 ± 0.054
2.737ProThr: 2.737 ± 0.044
4.063ProVal: 4.063 ± 0.051
0.661ProTrp: 0.661 ± 0.019
1.29ProTyr: 1.29 ± 0.03
0.0ProXaa: 0.0 ± 0.0
Gln
5.122GlnAla: 5.122 ± 0.07
0.281GlnCys: 0.281 ± 0.012
1.444GlnAsp: 1.444 ± 0.032
1.357GlnGlu: 1.357 ± 0.028
1.326GlnPhe: 1.326 ± 0.028
2.584GlnGly: 2.584 ± 0.053
0.917GlnHis: 0.917 ± 0.021
1.872GlnIle: 1.872 ± 0.029
0.965GlnLys: 0.965 ± 0.028
3.895GlnLeu: 3.895 ± 0.05
1.014GlnMet: 1.014 ± 0.026
0.996GlnAsn: 0.996 ± 0.031
2.041GlnPro: 2.041 ± 0.043
1.897GlnGln: 1.897 ± 0.046
2.867GlnArg: 2.867 ± 0.05
2.215GlnSer: 2.215 ± 0.051
2.196GlnThr: 2.196 ± 0.046
2.666GlnVal: 2.666 ± 0.048
0.627GlnTrp: 0.627 ± 0.02
1.045GlnTyr: 1.045 ± 0.033
0.0GlnXaa: 0.0 ± 0.0
Arg
8.344ArgAla: 8.344 ± 0.106
0.629ArgCys: 0.629 ± 0.021
3.631ArgAsp: 3.631 ± 0.052
4.355ArgGlu: 4.355 ± 0.069
2.976ArgPhe: 2.976 ± 0.046
4.466ArgGly: 4.466 ± 0.059
1.907ArgHis: 1.907 ± 0.04
3.509ArgIle: 3.509 ± 0.049
1.861ArgLys: 1.861 ± 0.039
7.44ArgLeu: 7.44 ± 0.084
1.788ArgMet: 1.788 ± 0.035
1.804ArgAsn: 1.804 ± 0.033
2.943ArgPro: 2.943 ± 0.042
2.469ArgGln: 2.469 ± 0.043
5.261ArgArg: 5.261 ± 0.091
3.453ArgSer: 3.453 ± 0.049
3.627ArgThr: 3.627 ± 0.058
5.293ArgVal: 5.293 ± 0.07
1.006ArgTrp: 1.006 ± 0.025
2.106ArgTyr: 2.106 ± 0.045
0.0ArgXaa: 0.0 ± 0.0
Ser
7.146SerAla: 7.146 ± 0.081
0.47SerCys: 0.47 ± 0.017
2.925SerAsp: 2.925 ± 0.048
2.629SerGlu: 2.629 ± 0.041
2.126SerPhe: 2.126 ± 0.04
5.524SerGly: 5.524 ± 0.101
1.324SerHis: 1.324 ± 0.03
2.78SerIle: 2.78 ± 0.04
1.536SerLys: 1.536 ± 0.025
6.017SerLeu: 6.017 ± 0.069
1.463SerMet: 1.463 ± 0.032
1.851SerAsn: 1.851 ± 0.053
2.973SerPro: 2.973 ± 0.049
1.957SerGln: 1.957 ± 0.038
3.575SerArg: 3.575 ± 0.05
3.726SerSer: 3.726 ± 0.066
3.532SerThr: 3.532 ± 0.085
4.53SerVal: 4.53 ± 0.065
0.75SerTrp: 0.75 ± 0.023
1.42SerTyr: 1.42 ± 0.036
0.0SerXaa: 0.0 ± 0.0
Thr
6.536ThrAla: 6.536 ± 0.089
0.432ThrCys: 0.432 ± 0.015
2.767ThrAsp: 2.767 ± 0.05
2.389ThrGlu: 2.389 ± 0.04
2.095ThrPhe: 2.095 ± 0.035
4.981ThrGly: 4.981 ± 0.094
1.344ThrHis: 1.344 ± 0.027
2.768ThrIle: 2.768 ± 0.054
1.304ThrLys: 1.304 ± 0.029
6.967ThrLeu: 6.967 ± 0.096
1.189ThrMet: 1.189 ± 0.03
1.649ThrAsn: 1.649 ± 0.047
3.579ThrPro: 3.579 ± 0.063
2.221ThrGln: 2.221 ± 0.053
3.692ThrArg: 3.692 ± 0.046
3.427ThrSer: 3.427 ± 0.066
3.492ThrThr: 3.492 ± 0.092
4.619ThrVal: 4.619 ± 0.078
0.702ThrTrp: 0.702 ± 0.024
1.408ThrTyr: 1.408 ± 0.044
0.0ThrXaa: 0.0 ± 0.0
Val
9.576ValAla: 9.576 ± 0.079
0.807ValCys: 0.807 ± 0.021
4.522ValAsp: 4.522 ± 0.062
4.124ValGlu: 4.124 ± 0.059
2.696ValPhe: 2.696 ± 0.043
5.585ValGly: 5.585 ± 0.065
1.594ValHis: 1.594 ± 0.032
3.471ValIle: 3.471 ± 0.051
2.383ValLys: 2.383 ± 0.046
7.849ValLeu: 7.849 ± 0.082
1.764ValMet: 1.764 ± 0.035
2.278ValAsn: 2.278 ± 0.059
4.141ValPro: 4.141 ± 0.062
2.655ValGln: 2.655 ± 0.044
5.189ValArg: 5.189 ± 0.059
4.742ValSer: 4.742 ± 0.062
4.898ValThr: 4.898 ± 0.087
6.328ValVal: 6.328 ± 0.082
0.967ValTrp: 0.967 ± 0.022
1.715ValTyr: 1.715 ± 0.035
0.0ValXaa: 0.0 ± 0.0
Trp
1.165TrpAla: 1.165 ± 0.026
0.156TrpCys: 0.156 ± 0.01
0.583TrpAsp: 0.583 ± 0.021
0.504TrpGlu: 0.504 ± 0.019
0.508TrpPhe: 0.508 ± 0.018
0.85TrpGly: 0.85 ± 0.026
0.42TrpHis: 0.42 ± 0.015
0.644TrpIle: 0.644 ± 0.021
0.377TrpLys: 0.377 ± 0.014
1.904TrpLeu: 1.904 ± 0.041
0.334TrpMet: 0.334 ± 0.015
0.442TrpAsn: 0.442 ± 0.017
0.7TrpPro: 0.7 ± 0.019
0.714TrpGln: 0.714 ± 0.021
1.274TrpArg: 1.274 ± 0.033
0.812TrpSer: 0.812 ± 0.024
0.718TrpThr: 0.718 ± 0.03
0.916TrpVal: 0.916 ± 0.023
0.245TrpTrp: 0.245 ± 0.012
0.318TrpTyr: 0.318 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.987TyrAla: 2.987 ± 0.046
0.264TyrCys: 0.264 ± 0.011
1.612TyrAsp: 1.612 ± 0.082
1.317TyrGlu: 1.317 ± 0.032
1.037TyrPhe: 1.037 ± 0.026
2.204TyrGly: 2.204 ± 0.035
0.508TyrHis: 0.508 ± 0.018
0.8TyrIle: 0.8 ± 0.025
0.618TyrLys: 0.618 ± 0.021
2.551TyrLeu: 2.551 ± 0.043
0.429TyrMet: 0.429 ± 0.018
0.677TyrAsn: 0.677 ± 0.025
1.218TyrPro: 1.218 ± 0.03
0.932TyrGln: 0.932 ± 0.025
2.074TyrArg: 2.074 ± 0.038
1.313TyrSer: 1.313 ± 0.039
1.436TyrThr: 1.436 ± 0.04
2.005TyrVal: 2.005 ± 0.036
0.39TyrTrp: 0.39 ± 0.018
0.709TyrTyr: 0.709 ± 0.025
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5256 proteins (1758797 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski