Amino acid dipepetide frequency for Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.018AlaAla: 5.018 ± 0.089
0.64AlaCys: 0.64 ± 0.025
3.467AlaAsp: 3.467 ± 0.059
4.77AlaGlu: 4.77 ± 0.073
3.274AlaPhe: 3.274 ± 0.055
5.021AlaGly: 5.021 ± 0.079
1.241AlaHis: 1.241 ± 0.034
4.654AlaIle: 4.654 ± 0.072
4.62AlaLys: 4.62 ± 0.07
7.188AlaLeu: 7.188 ± 0.099
1.597AlaMet: 1.597 ± 0.039
3.034AlaAsn: 3.034 ± 0.066
2.356AlaPro: 2.356 ± 0.059
2.898AlaGln: 2.898 ± 0.05
2.61AlaArg: 2.61 ± 0.053
4.29AlaSer: 4.29 ± 0.085
3.462AlaThr: 3.462 ± 0.107
4.318AlaVal: 4.318 ± 0.069
0.846AlaTrp: 0.846 ± 0.026
2.753AlaTyr: 2.753 ± 0.052
0.0AlaXaa: 0.0 ± 0.0
Cys
0.46CysAla: 0.46 ± 0.019
0.096CysCys: 0.096 ± 0.009
0.35CysAsp: 0.35 ± 0.02
0.45CysGlu: 0.45 ± 0.024
0.374CysPhe: 0.374 ± 0.019
0.662CysGly: 0.662 ± 0.053
0.161CysHis: 0.161 ± 0.012
0.534CysIle: 0.534 ± 0.019
0.466CysLys: 0.466 ± 0.022
0.661CysLeu: 0.661 ± 0.024
0.178CysMet: 0.178 ± 0.012
0.357CysAsn: 0.357 ± 0.02
0.345CysPro: 0.345 ± 0.024
0.254CysGln: 0.254 ± 0.015
0.284CysArg: 0.284 ± 0.016
0.545CysSer: 0.545 ± 0.022
0.476CysThr: 0.476 ± 0.03
0.441CysVal: 0.441 ± 0.024
0.07CysTrp: 0.07 ± 0.007
0.29CysTyr: 0.29 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
3.553AspAla: 3.553 ± 0.071
0.336AspCys: 0.336 ± 0.021
2.08AspAsp: 2.08 ± 0.044
3.282AspGlu: 3.282 ± 0.056
3.2AspPhe: 3.2 ± 0.065
3.74AspGly: 3.74 ± 0.067
1.09AspHis: 1.09 ± 0.029
3.72AspIle: 3.72 ± 0.064
3.577AspLys: 3.577 ± 0.059
5.528AspLeu: 5.528 ± 0.082
1.055AspMet: 1.055 ± 0.031
2.1AspAsn: 2.1 ± 0.043
2.237AspPro: 2.237 ± 0.05
1.879AspGln: 1.879 ± 0.044
2.137AspArg: 2.137 ± 0.044
2.686AspSer: 2.686 ± 0.049
2.326AspThr: 2.326 ± 0.047
2.978AspVal: 2.978 ± 0.051
0.827AspTrp: 0.827 ± 0.027
2.437AspTyr: 2.437 ± 0.048
0.0AspXaa: 0.0 ± 0.0
Glu
4.6GluAla: 4.6 ± 0.059
0.346GluCys: 0.346 ± 0.017
3.444GluAsp: 3.444 ± 0.055
5.471GluGlu: 5.471 ± 0.101
2.833GluPhe: 2.833 ± 0.046
4.439GluGly: 4.439 ± 0.074
1.166GluHis: 1.166 ± 0.035
5.164GluIle: 5.164 ± 0.071
5.737GluLys: 5.737 ± 0.082
6.19GluLeu: 6.19 ± 0.084
1.613GluMet: 1.613 ± 0.037
3.928GluAsn: 3.928 ± 0.052
1.869GluPro: 1.869 ± 0.048
2.2GluGln: 2.2 ± 0.046
3.02GluArg: 3.02 ± 0.053
3.205GluSer: 3.205 ± 0.055
3.032GluThr: 3.032 ± 0.053
4.98GluVal: 4.98 ± 0.063
0.842GluTrp: 0.842 ± 0.027
2.549GluTyr: 2.549 ± 0.05
0.0GluXaa: 0.0 ± 0.0
Phe
3.052PheAla: 3.052 ± 0.056
0.431PheCys: 0.431 ± 0.021
2.821PheAsp: 2.821 ± 0.053
3.195PheGlu: 3.195 ± 0.06
2.537PhePhe: 2.537 ± 0.055
3.587PheGly: 3.587 ± 0.055
1.033PheHis: 1.033 ± 0.032
3.229PheIle: 3.229 ± 0.059
3.105PheLys: 3.105 ± 0.056
4.981PheLeu: 4.981 ± 0.092
1.119PheMet: 1.119 ± 0.034
2.422PheAsn: 2.422 ± 0.048
1.95PhePro: 1.95 ± 0.04
1.81PheGln: 1.81 ± 0.038
2.046PheArg: 2.046 ± 0.049
3.845PheSer: 3.845 ± 0.055
2.908PheThr: 2.908 ± 0.053
2.974PheVal: 2.974 ± 0.054
0.639PheTrp: 0.639 ± 0.024
2.112PheTyr: 2.112 ± 0.045
0.0PheXaa: 0.0 ± 0.0
Gly
4.56GlyAla: 4.56 ± 0.084
0.587GlyCys: 0.587 ± 0.039
3.311GlyAsp: 3.311 ± 0.062
4.236GlyGlu: 4.236 ± 0.061
3.766GlyPhe: 3.766 ± 0.064
5.173GlyGly: 5.173 ± 0.094
1.238GlyHis: 1.238 ± 0.037
5.642GlyIle: 5.642 ± 0.086
5.764GlyLys: 5.764 ± 0.075
6.642GlyLeu: 6.642 ± 0.093
1.729GlyMet: 1.729 ± 0.039
3.607GlyAsn: 3.607 ± 0.066
1.725GlyPro: 1.725 ± 0.042
2.475GlyGln: 2.475 ± 0.049
2.833GlyArg: 2.833 ± 0.048
4.484GlySer: 4.484 ± 0.082
4.227GlyThr: 4.227 ± 0.121
4.827GlyVal: 4.827 ± 0.075
0.998GlyTrp: 0.998 ± 0.028
2.977GlyTyr: 2.977 ± 0.054
0.0GlyXaa: 0.0 ± 0.0
His
1.186HisAla: 1.186 ± 0.034
0.189HisCys: 0.189 ± 0.013
0.788HisAsp: 0.788 ± 0.026
1.095HisGlu: 1.095 ± 0.03
1.246HisPhe: 1.246 ± 0.034
1.27HisGly: 1.27 ± 0.033
0.544HisHis: 0.544 ± 0.022
1.297HisIle: 1.297 ± 0.038
1.085HisLys: 1.085 ± 0.03
2.203HisLeu: 2.203 ± 0.039
0.368HisMet: 0.368 ± 0.018
0.782HisAsn: 0.782 ± 0.025
1.113HisPro: 1.113 ± 0.033
0.832HisGln: 0.832 ± 0.028
0.85HisArg: 0.85 ± 0.029
1.219HisSer: 1.219 ± 0.031
1.02HisThr: 1.02 ± 0.028
1.006HisVal: 1.006 ± 0.031
0.302HisTrp: 0.302 ± 0.017
0.929HisTyr: 0.929 ± 0.028
0.0HisXaa: 0.0 ± 0.0
Ile
4.613IleAla: 4.613 ± 0.064
0.635IleCys: 0.635 ± 0.026
3.68IleAsp: 3.68 ± 0.049
4.504IleGlu: 4.504 ± 0.075
3.321IlePhe: 3.321 ± 0.063
4.824IleGly: 4.824 ± 0.077
1.493IleHis: 1.493 ± 0.033
4.444IleIle: 4.444 ± 0.072
4.775IleLys: 4.775 ± 0.074
7.156IleLeu: 7.156 ± 0.105
1.327IleMet: 1.327 ± 0.037
3.381IleAsn: 3.381 ± 0.061
3.28IlePro: 3.28 ± 0.055
2.829IleGln: 2.829 ± 0.053
3.158IleArg: 3.158 ± 0.054
5.337IleSer: 5.337 ± 0.084
3.863IleThr: 3.863 ± 0.071
3.925IleVal: 3.925 ± 0.062
0.763IleTrp: 0.763 ± 0.03
2.549IleTyr: 2.549 ± 0.053
0.0IleXaa: 0.0 ± 0.0
Lys
5.063LysAla: 5.063 ± 0.073
0.354LysCys: 0.354 ± 0.02
4.039LysAsp: 4.039 ± 0.059
5.763LysGlu: 5.763 ± 0.08
2.656LysPhe: 2.656 ± 0.054
5.068LysGly: 5.068 ± 0.066
1.283LysHis: 1.283 ± 0.034
5.149LysIle: 5.149 ± 0.08
5.7LysLys: 5.7 ± 0.082
5.768LysLeu: 5.768 ± 0.073
1.881LysMet: 1.881 ± 0.039
4.132LysAsn: 4.132 ± 0.069
2.668LysPro: 2.668 ± 0.058
2.168LysGln: 2.168 ± 0.049
3.004LysArg: 3.004 ± 0.056
4.282LysSer: 4.282 ± 0.06
3.714LysThr: 3.714 ± 0.056
5.286LysVal: 5.286 ± 0.072
0.999LysTrp: 0.999 ± 0.033
3.01LysTyr: 3.01 ± 0.053
0.0LysXaa: 0.0 ± 0.0
Leu
6.594LeuAla: 6.594 ± 0.076
0.743LeuCys: 0.743 ± 0.027
5.018LeuAsp: 5.018 ± 0.094
6.359LeuGlu: 6.359 ± 0.094
4.763LeuPhe: 4.763 ± 0.075
6.739LeuGly: 6.739 ± 0.081
1.856LeuHis: 1.856 ± 0.043
6.376LeuIle: 6.376 ± 0.089
7.435LeuLys: 7.435 ± 0.1
9.616LeuLeu: 9.616 ± 0.122
2.241LeuMet: 2.241 ± 0.046
5.191LeuAsn: 5.191 ± 0.068
4.389LeuPro: 4.389 ± 0.062
3.719LeuGln: 3.719 ± 0.06
4.096LeuArg: 4.096 ± 0.064
7.253LeuSer: 7.253 ± 0.081
4.978LeuThr: 4.978 ± 0.061
5.804LeuVal: 5.804 ± 0.09
1.115LeuTrp: 1.115 ± 0.03
3.466LeuTyr: 3.466 ± 0.058
0.0LeuXaa: 0.0 ± 0.0
Met
1.76MetAla: 1.76 ± 0.033
0.123MetCys: 0.123 ± 0.012
1.181MetAsp: 1.181 ± 0.033
1.58MetGlu: 1.58 ± 0.037
0.803MetPhe: 0.803 ± 0.027
1.626MetGly: 1.626 ± 0.041
0.4MetHis: 0.4 ± 0.018
1.475MetIle: 1.475 ± 0.031
2.184MetLys: 2.184 ± 0.044
1.909MetLeu: 1.909 ± 0.039
0.576MetMet: 0.576 ± 0.021
1.22MetAsn: 1.22 ± 0.034
0.934MetPro: 0.934 ± 0.027
0.763MetGln: 0.763 ± 0.025
1.077MetArg: 1.077 ± 0.033
1.402MetSer: 1.402 ± 0.032
1.071MetThr: 1.071 ± 0.031
1.423MetVal: 1.423 ± 0.037
0.216MetTrp: 0.216 ± 0.013
0.733MetTyr: 0.733 ± 0.029
0.0MetXaa: 0.0 ± 0.0
Asn
3.655AsnAla: 3.655 ± 0.062
0.359AsnCys: 0.359 ± 0.023
2.185AsnAsp: 2.185 ± 0.045
2.806AsnGlu: 2.806 ± 0.042
2.603AsnPhe: 2.603 ± 0.048
3.772AsnGly: 3.772 ± 0.094
1.027AsnHis: 1.027 ± 0.03
3.487AsnIle: 3.487 ± 0.062
3.123AsnLys: 3.123 ± 0.057
5.043AsnLeu: 5.043 ± 0.068
1.02AsnMet: 1.02 ± 0.028
2.415AsnAsn: 2.415 ± 0.06
2.687AsnPro: 2.687 ± 0.055
1.822AsnGln: 1.822 ± 0.043
2.302AsnArg: 2.302 ± 0.048
3.185AsnSer: 3.185 ± 0.064
2.935AsnThr: 2.935 ± 0.05
3.04AsnVal: 3.04 ± 0.066
0.684AsnTrp: 0.684 ± 0.027
2.423AsnTyr: 2.423 ± 0.051
0.0AsnXaa: 0.0 ± 0.0
Pro
2.585ProAla: 2.585 ± 0.054
0.242ProCys: 0.242 ± 0.015
2.411ProAsp: 2.411 ± 0.047
3.429ProGlu: 3.429 ± 0.062
1.976ProPhe: 1.976 ± 0.046
2.717ProGly: 2.717 ± 0.048
0.784ProHis: 0.784 ± 0.032
2.555ProIle: 2.555 ± 0.054
2.513ProLys: 2.513 ± 0.05
3.593ProLeu: 3.593 ± 0.06
0.843ProMet: 0.843 ± 0.027
2.054ProAsn: 2.054 ± 0.054
1.081ProPro: 1.081 ± 0.043
1.54ProGln: 1.54 ± 0.04
1.176ProArg: 1.176 ± 0.03
2.598ProSer: 2.598 ± 0.054
2.228ProThr: 2.228 ± 0.053
2.81ProVal: 2.81 ± 0.054
0.457ProTrp: 0.457 ± 0.018
1.779ProTyr: 1.779 ± 0.042
0.0ProXaa: 0.0 ± 0.0
Gln
2.56GlnAla: 2.56 ± 0.05
0.201GlnCys: 0.201 ± 0.014
1.74GlnAsp: 1.74 ± 0.041
2.535GlnGlu: 2.535 ± 0.05
1.647GlnPhe: 1.647 ± 0.037
2.253GlnGly: 2.253 ± 0.038
0.668GlnHis: 0.668 ± 0.024
2.836GlnIle: 2.836 ± 0.057
2.998GlnLys: 2.998 ± 0.062
3.291GlnLeu: 3.291 ± 0.054
0.932GlnMet: 0.932 ± 0.025
2.127GlnAsn: 2.127 ± 0.046
1.181GlnPro: 1.181 ± 0.032
1.226GlnGln: 1.226 ± 0.04
1.604GlnArg: 1.604 ± 0.037
2.147GlnSer: 2.147 ± 0.048
1.885GlnThr: 1.885 ± 0.044
2.396GlnVal: 2.396 ± 0.046
0.549GlnTrp: 0.549 ± 0.023
1.506GlnTyr: 1.506 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
2.654ArgAla: 2.654 ± 0.048
0.229ArgCys: 0.229 ± 0.012
2.066ArgAsp: 2.066 ± 0.042
2.724ArgGlu: 2.724 ± 0.046
2.239ArgPhe: 2.239 ± 0.049
2.4ArgGly: 2.4 ± 0.047
0.686ArgHis: 0.686 ± 0.027
3.407ArgIle: 3.407 ± 0.056
3.21ArgLys: 3.21 ± 0.053
3.924ArgLeu: 3.924 ± 0.061
1.157ArgMet: 1.157 ± 0.03
2.287ArgAsn: 2.287 ± 0.051
1.535ArgPro: 1.535 ± 0.038
1.457ArgGln: 1.457 ± 0.039
1.784ArgArg: 1.784 ± 0.044
2.415ArgSer: 2.415 ± 0.051
2.276ArgThr: 2.276 ± 0.048
2.646ArgVal: 2.646 ± 0.052
0.625ArgTrp: 0.625 ± 0.023
1.841ArgTyr: 1.841 ± 0.038
0.0ArgXaa: 0.0 ± 0.0
Ser
4.49SerAla: 4.49 ± 0.085
0.599SerCys: 0.599 ± 0.026
3.147SerAsp: 3.147 ± 0.055
3.921SerGlu: 3.921 ± 0.063
3.487SerPhe: 3.487 ± 0.059
5.066SerGly: 5.066 ± 0.066
1.239SerHis: 1.239 ± 0.031
4.589SerIle: 4.589 ± 0.077
4.288SerLys: 4.288 ± 0.064
6.478SerLeu: 6.478 ± 0.09
1.305SerMet: 1.305 ± 0.031
3.029SerAsn: 3.029 ± 0.063
2.692SerPro: 2.692 ± 0.054
2.032SerGln: 2.032 ± 0.04
2.549SerArg: 2.549 ± 0.048
4.504SerSer: 4.504 ± 0.074
3.921SerThr: 3.921 ± 0.059
4.013SerVal: 4.013 ± 0.065
0.817SerTrp: 0.817 ± 0.031
2.82SerTyr: 2.82 ± 0.058
0.0SerXaa: 0.0 ± 0.0
Thr
3.858ThrAla: 3.858 ± 0.114
0.389ThrCys: 0.389 ± 0.034
2.77ThrAsp: 2.77 ± 0.058
3.182ThrGlu: 3.182 ± 0.049
2.894ThrPhe: 2.894 ± 0.048
4.275ThrGly: 4.275 ± 0.089
1.067ThrHis: 1.067 ± 0.03
3.427ThrIle: 3.427 ± 0.064
3.034ThrLys: 3.034 ± 0.055
5.799ThrLeu: 5.799 ± 0.077
0.894ThrMet: 0.894 ± 0.028
2.299ThrAsn: 2.299 ± 0.06
2.596ThrPro: 2.596 ± 0.049
1.923ThrGln: 1.923 ± 0.047
2.007ThrArg: 2.007 ± 0.042
3.553ThrSer: 3.553 ± 0.072
2.927ThrThr: 2.927 ± 0.069
3.674ThrVal: 3.674 ± 0.095
0.758ThrTrp: 0.758 ± 0.026
2.48ThrTyr: 2.48 ± 0.068
0.0ThrXaa: 0.0 ± 0.0
Val
4.277ValAla: 4.277 ± 0.068
0.545ValCys: 0.545 ± 0.036
3.433ValAsp: 3.433 ± 0.062
4.169ValGlu: 4.169 ± 0.066
3.125ValPhe: 3.125 ± 0.05
4.343ValGly: 4.343 ± 0.07
1.171ValHis: 1.171 ± 0.031
4.412ValIle: 4.412 ± 0.068
4.661ValLys: 4.661 ± 0.056
6.371ValLeu: 6.371 ± 0.088
1.43ValMet: 1.43 ± 0.039
3.327ValAsn: 3.327 ± 0.06
2.643ValPro: 2.643 ± 0.057
2.262ValGln: 2.262 ± 0.044
2.561ValArg: 2.561 ± 0.045
4.334ValSer: 4.334 ± 0.061
3.31ValThr: 3.31 ± 0.123
4.296ValVal: 4.296 ± 0.075
0.756ValTrp: 0.756 ± 0.024
2.493ValTyr: 2.493 ± 0.046
0.0ValXaa: 0.0 ± 0.0
Trp
0.912TrpAla: 0.912 ± 0.029
0.107TrpCys: 0.107 ± 0.01
0.71TrpAsp: 0.71 ± 0.027
0.88TrpGlu: 0.88 ± 0.031
0.547TrpPhe: 0.547 ± 0.021
0.949TrpGly: 0.949 ± 0.031
0.253TrpHis: 0.253 ± 0.014
0.942TrpIle: 0.942 ± 0.034
1.051TrpLys: 1.051 ± 0.035
1.126TrpLeu: 1.126 ± 0.032
0.38TrpMet: 0.38 ± 0.02
0.769TrpAsn: 0.769 ± 0.025
0.33TrpPro: 0.33 ± 0.018
0.519TrpGln: 0.519 ± 0.021
0.521TrpArg: 0.521 ± 0.024
0.787TrpSer: 0.787 ± 0.036
0.697TrpThr: 0.697 ± 0.027
0.851TrpVal: 0.851 ± 0.03
0.199TrpTrp: 0.199 ± 0.014
0.496TrpTyr: 0.496 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.608TyrAla: 2.608 ± 0.051
0.305TyrCys: 0.305 ± 0.015
2.124TyrAsp: 2.124 ± 0.039
2.274TyrGlu: 2.274 ± 0.045
2.502TyrPhe: 2.502 ± 0.052
2.875TyrGly: 2.875 ± 0.052
0.923TyrHis: 0.923 ± 0.027
2.52TyrIle: 2.52 ± 0.05
2.66TyrLys: 2.66 ± 0.051
4.285TyrLeu: 4.285 ± 0.068
0.813TyrMet: 0.813 ± 0.028
2.112TyrAsn: 2.112 ± 0.052
1.759TyrPro: 1.759 ± 0.04
1.674TyrGln: 1.674 ± 0.036
1.943TyrArg: 1.943 ± 0.049
2.918TyrSer: 2.918 ± 0.057
2.55TyrThr: 2.55 ± 0.067
2.232TyrVal: 2.232 ± 0.042
0.565TyrTrp: 0.565 ± 0.022
1.965TyrTyr: 1.965 ± 0.049
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3429 proteins (1198587 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski