Amino acid dipepetide frequency for Jembrana disease virus (JDV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.604AlaAla: 6.604 ± 1.436
1.376AlaCys: 1.376 ± 0.391
1.101AlaAsp: 1.101 ± 0.286
4.678AlaGlu: 4.678 ± 1.256
2.201AlaPhe: 2.201 ± 0.463
3.302AlaGly: 3.302 ± 1.11
0.826AlaHis: 0.826 ± 0.369
4.678AlaIle: 4.678 ± 1.355
0.275AlaLys: 0.275 ± 0.183
6.054AlaLeu: 6.054 ± 1.483
1.101AlaMet: 1.101 ± 0.471
2.477AlaAsn: 2.477 ± 0.629
3.853AlaPro: 3.853 ± 1.675
4.678AlaGln: 4.678 ± 1.188
5.228AlaArg: 5.228 ± 1.51
1.101AlaSer: 1.101 ± 0.65
3.027AlaThr: 3.027 ± 0.803
4.678AlaVal: 4.678 ± 1.004
0.55AlaTrp: 0.55 ± 0.303
2.477AlaTyr: 2.477 ± 0.516
0.0AlaXaa: 0.0 ± 0.0
Cys
1.651CysAla: 1.651 ± 1.479
0.55CysCys: 0.55 ± 0.303
0.55CysAsp: 0.55 ± 0.24
0.55CysGlu: 0.55 ± 0.367
1.926CysPhe: 1.926 ± 0.528
2.201CysGly: 2.201 ± 0.55
0.275CysHis: 0.275 ± 0.254
1.376CysIle: 1.376 ± 0.397
1.926CysLys: 1.926 ± 0.856
1.101CysLeu: 1.101 ± 0.567
0.55CysMet: 0.55 ± 0.389
0.275CysAsn: 0.275 ± 0.354
1.926CysPro: 1.926 ± 1.081
1.651CysGln: 1.651 ± 0.93
3.302CysArg: 3.302 ± 1.223
1.651CysSer: 1.651 ± 0.507
0.0CysThr: 0.0 ± 0.0
1.926CysVal: 1.926 ± 0.861
0.826CysTrp: 0.826 ± 0.792
0.55CysTyr: 0.55 ± 0.303
0.0CysXaa: 0.0 ± 0.0
Asp
1.101AspAla: 1.101 ± 0.286
3.027AspCys: 3.027 ± 0.699
1.926AspAsp: 1.926 ± 0.765
3.027AspGlu: 3.027 ± 1.02
0.55AspPhe: 0.55 ± 0.367
4.678AspGly: 4.678 ± 0.748
3.027AspHis: 3.027 ± 0.651
3.027AspIle: 3.027 ± 0.814
1.926AspLys: 1.926 ± 0.519
7.155AspLeu: 7.155 ± 1.638
1.101AspMet: 1.101 ± 0.546
1.101AspAsn: 1.101 ± 0.495
1.926AspPro: 1.926 ± 0.445
1.376AspGln: 1.376 ± 0.78
3.302AspArg: 3.302 ± 0.665
1.926AspSer: 1.926 ± 0.4
3.027AspThr: 3.027 ± 0.805
0.55AspVal: 0.55 ± 0.24
1.376AspTrp: 1.376 ± 0.575
0.275AspTyr: 0.275 ± 0.183
0.0AspXaa: 0.0 ± 0.0
Glu
6.879GluAla: 6.879 ± 1.604
1.101GluCys: 1.101 ± 0.559
4.128GluAsp: 4.128 ± 1.248
9.631GluGlu: 9.631 ± 1.446
1.651GluPhe: 1.651 ± 0.391
6.054GluGly: 6.054 ± 1.165
1.101GluHis: 1.101 ± 0.497
5.228GluIle: 5.228 ± 2.051
5.228GluLys: 5.228 ± 1.311
6.054GluLeu: 6.054 ± 1.188
1.926GluMet: 1.926 ± 1.438
2.477GluAsn: 2.477 ± 0.513
2.477GluPro: 2.477 ± 0.614
1.651GluGln: 1.651 ± 0.433
5.504GluArg: 5.504 ± 1.101
3.577GluSer: 3.577 ± 1.175
2.201GluThr: 2.201 ± 0.876
4.953GluVal: 4.953 ± 1.311
1.376GluTrp: 1.376 ± 0.443
1.376GluTyr: 1.376 ± 0.54
0.0GluXaa: 0.0 ± 0.0
Phe
1.651PheAla: 1.651 ± 0.566
1.651PheCys: 1.651 ± 0.919
0.55PheAsp: 0.55 ± 0.509
1.101PheGlu: 1.101 ± 0.474
0.275PhePhe: 0.275 ± 0.254
0.826PheGly: 0.826 ± 0.564
0.0PheHis: 0.0 ± 0.0
1.651PheIle: 1.651 ± 0.686
1.651PheLys: 1.651 ± 0.539
3.027PheLeu: 3.027 ± 0.522
0.0PheMet: 0.0 ± 0.0
0.275PheAsn: 0.275 ± 0.183
2.201PhePro: 2.201 ± 0.861
2.201PheGln: 2.201 ± 0.496
1.376PheArg: 1.376 ± 0.563
1.101PheSer: 1.101 ± 0.516
1.376PheThr: 1.376 ± 0.47
1.651PheVal: 1.651 ± 0.421
2.201PheTrp: 2.201 ± 0.84
0.275PheTyr: 0.275 ± 0.183
0.0PheXaa: 0.0 ± 0.0
Gly
2.752GlyAla: 2.752 ± 0.948
1.651GlyCys: 1.651 ± 0.745
4.678GlyAsp: 4.678 ± 2.112
5.228GlyGlu: 5.228 ± 0.84
1.651GlyPhe: 1.651 ± 0.671
9.356GlyGly: 9.356 ± 3.168
3.853GlyHis: 3.853 ± 1.008
4.953GlyIle: 4.953 ± 0.988
7.705GlyLys: 7.705 ± 0.767
5.504GlyLeu: 5.504 ± 0.581
1.376GlyMet: 1.376 ± 0.397
2.752GlyAsn: 2.752 ± 1.022
5.779GlyPro: 5.779 ± 2.263
1.376GlyGln: 1.376 ± 0.661
8.255GlyArg: 8.255 ± 2.712
3.577GlySer: 3.577 ± 0.581
3.853GlyThr: 3.853 ± 0.925
3.577GlyVal: 3.577 ± 0.795
2.201GlyTrp: 2.201 ± 1.135
1.651GlyTyr: 1.651 ± 0.602
0.0GlyXaa: 0.0 ± 0.0
His
2.477HisAla: 2.477 ± 0.879
0.55HisCys: 0.55 ± 0.613
1.101HisAsp: 1.101 ± 0.667
0.55HisGlu: 0.55 ± 0.24
1.101HisPhe: 1.101 ± 0.664
1.651HisGly: 1.651 ± 0.438
1.926HisHis: 1.926 ± 0.61
1.926HisIle: 1.926 ± 0.445
0.55HisLys: 0.55 ± 0.367
2.477HisLeu: 2.477 ± 0.503
0.275HisMet: 0.275 ± 0.183
0.55HisAsn: 0.55 ± 0.613
2.477HisPro: 2.477 ± 0.66
1.101HisGln: 1.101 ± 0.573
2.477HisArg: 2.477 ± 0.43
0.275HisSer: 0.275 ± 0.183
2.477HisThr: 2.477 ± 1.268
0.826HisVal: 0.826 ± 0.562
1.101HisTrp: 1.101 ± 0.48
0.826HisTyr: 0.826 ± 0.598
0.0HisXaa: 0.0 ± 0.0
Ile
1.651IleAla: 1.651 ± 0.709
0.55IleCys: 0.55 ± 0.613
1.651IleAsp: 1.651 ± 0.539
2.752IleGlu: 2.752 ± 0.491
1.101IlePhe: 1.101 ± 0.48
5.228IleGly: 5.228 ± 1.179
1.926IleHis: 1.926 ± 0.528
2.752IleIle: 2.752 ± 0.913
3.027IleLys: 3.027 ± 2.017
5.779IleLeu: 5.779 ± 1.971
1.101IleMet: 1.101 ± 0.48
2.477IleAsn: 2.477 ± 0.612
4.128IlePro: 4.128 ± 1.561
3.577IleGln: 3.577 ± 0.969
5.779IleArg: 5.779 ± 0.666
1.651IleSer: 1.651 ± 0.623
3.577IleThr: 3.577 ± 0.972
2.752IleVal: 2.752 ± 1.326
1.376IleTrp: 1.376 ± 0.391
1.926IleTyr: 1.926 ± 0.404
0.0IleXaa: 0.0 ± 0.0
Lys
2.201LysAla: 2.201 ± 0.995
2.477LysCys: 2.477 ± 1.201
2.477LysAsp: 2.477 ± 1.347
5.228LysGlu: 5.228 ± 0.542
0.55LysPhe: 0.55 ± 0.367
9.081LysGly: 9.081 ± 1.124
1.926LysHis: 1.926 ± 0.578
6.054LysIle: 6.054 ± 1.575
3.577LysLys: 3.577 ± 1.109
5.779LysLeu: 5.779 ± 1.331
1.101LysMet: 1.101 ± 0.497
2.752LysAsn: 2.752 ± 0.785
1.926LysPro: 1.926 ± 0.602
2.477LysGln: 2.477 ± 0.775
3.302LysArg: 3.302 ± 0.95
2.477LysSer: 2.477 ± 0.916
2.201LysThr: 2.201 ± 0.995
3.027LysVal: 3.027 ± 0.923
1.376LysTrp: 1.376 ± 0.464
1.651LysTyr: 1.651 ± 0.539
0.0LysXaa: 0.0 ± 0.0
Leu
4.403LeuAla: 4.403 ± 1.251
1.651LeuCys: 1.651 ± 0.993
5.504LeuAsp: 5.504 ± 1.358
8.255LeuGlu: 8.255 ± 1.01
1.926LeuPhe: 1.926 ± 0.767
5.779LeuGly: 5.779 ± 0.874
1.376LeuHis: 1.376 ± 0.78
3.853LeuIle: 3.853 ± 0.923
6.329LeuLys: 6.329 ± 1.662
9.631LeuLeu: 9.631 ± 1.608
1.926LeuMet: 1.926 ± 0.772
3.027LeuAsn: 3.027 ± 0.722
2.752LeuPro: 2.752 ± 0.737
6.604LeuGln: 6.604 ± 0.554
3.853LeuArg: 3.853 ± 1.169
7.98LeuSer: 7.98 ± 2.756
6.604LeuThr: 6.604 ± 1.04
6.329LeuVal: 6.329 ± 1.768
2.477LeuTrp: 2.477 ± 0.679
0.826LeuTyr: 0.826 ± 0.415
0.0LeuXaa: 0.0 ± 0.0
Met
2.201MetAla: 2.201 ± 0.55
0.55MetCys: 0.55 ± 0.303
0.826MetAsp: 0.826 ± 0.55
1.926MetGlu: 1.926 ± 0.638
0.0MetPhe: 0.0 ± 0.0
0.826MetGly: 0.826 ± 0.45
0.275MetHis: 0.275 ± 0.354
0.55MetIle: 0.55 ± 0.367
0.826MetLys: 0.826 ± 0.369
1.376MetLeu: 1.376 ± 0.563
1.376MetMet: 1.376 ± 0.758
0.826MetAsn: 0.826 ± 0.34
0.826MetPro: 0.826 ± 0.598
0.55MetGln: 0.55 ± 0.303
1.926MetArg: 1.926 ± 0.601
1.376MetSer: 1.376 ± 0.81
1.376MetThr: 1.376 ± 0.728
1.101MetVal: 1.101 ± 0.864
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.201AsnAla: 2.201 ± 0.655
2.201AsnCys: 2.201 ± 0.737
0.826AsnAsp: 0.826 ± 0.574
1.376AsnGlu: 1.376 ± 0.354
1.376AsnPhe: 1.376 ± 0.391
1.101AsnGly: 1.101 ± 0.667
0.826AsnHis: 0.826 ± 0.343
2.752AsnIle: 2.752 ± 0.593
2.477AsnLys: 2.477 ± 1.053
3.302AsnLeu: 3.302 ± 1.239
0.275AsnMet: 0.275 ± 0.254
0.55AsnAsn: 0.55 ± 0.24
2.477AsnPro: 2.477 ± 0.933
1.926AsnGln: 1.926 ± 0.494
2.201AsnArg: 2.201 ± 1.032
1.926AsnSer: 1.926 ± 0.404
4.678AsnThr: 4.678 ± 1.044
2.477AsnVal: 2.477 ± 0.644
0.826AsnTrp: 0.826 ± 0.648
0.826AsnTyr: 0.826 ± 0.763
0.0AsnXaa: 0.0 ± 0.0
Pro
4.403ProAla: 4.403 ± 1.661
1.101ProCys: 1.101 ± 0.516
3.027ProAsp: 3.027 ± 1.284
6.879ProGlu: 6.879 ± 0.995
1.651ProPhe: 1.651 ± 0.496
5.779ProGly: 5.779 ± 1.426
0.55ProHis: 0.55 ± 0.34
3.027ProIle: 3.027 ± 0.58
3.302ProLys: 3.302 ± 1.581
4.128ProLeu: 4.128 ± 0.89
1.101ProMet: 1.101 ± 0.726
1.101ProAsn: 1.101 ± 0.509
3.577ProPro: 3.577 ± 1.379
3.302ProGln: 3.302 ± 1.3
4.678ProArg: 4.678 ± 0.498
4.128ProSer: 4.128 ± 1.675
1.651ProThr: 1.651 ± 0.537
3.853ProVal: 3.853 ± 0.757
1.651ProTrp: 1.651 ± 0.672
1.651ProTyr: 1.651 ± 0.82
0.0ProXaa: 0.0 ± 0.0
Gln
2.477GlnAla: 2.477 ± 0.798
0.826GlnCys: 0.826 ± 0.343
1.376GlnAsp: 1.376 ± 0.653
4.403GlnGlu: 4.403 ± 0.636
0.55GlnPhe: 0.55 ± 0.303
2.201GlnGly: 2.201 ± 0.721
1.376GlnHis: 1.376 ± 1.033
1.376GlnIle: 1.376 ± 0.563
4.403GlnLys: 4.403 ± 0.741
4.403GlnLeu: 4.403 ± 0.961
0.55GlnMet: 0.55 ± 0.367
2.752GlnAsn: 2.752 ± 1.315
1.651GlnPro: 1.651 ± 0.631
2.201GlnGln: 2.201 ± 0.714
5.504GlnArg: 5.504 ± 1.378
3.027GlnSer: 3.027 ± 0.97
2.201GlnThr: 2.201 ± 0.826
1.651GlnVal: 1.651 ± 0.919
2.201GlnTrp: 2.201 ± 0.572
1.651GlnTyr: 1.651 ± 0.391
0.0GlnXaa: 0.0 ± 0.0
Arg
3.302ArgAla: 3.302 ± 0.618
0.826ArgCys: 0.826 ± 0.369
3.853ArgAsp: 3.853 ± 0.603
6.604ArgGlu: 6.604 ± 1.758
2.477ArgPhe: 2.477 ± 0.889
6.604ArgGly: 6.604 ± 3.1
1.376ArgHis: 1.376 ± 0.874
1.926ArgIle: 1.926 ± 0.781
5.228ArgLys: 5.228 ± 1.07
3.577ArgLeu: 3.577 ± 0.87
1.926ArgMet: 1.926 ± 1.004
2.752ArgAsn: 2.752 ± 0.986
5.779ArgPro: 5.779 ± 2.645
2.477ArgGln: 2.477 ± 0.58
6.604ArgArg: 6.604 ± 2.985
3.302ArgSer: 3.302 ± 1.376
2.752ArgThr: 2.752 ± 0.988
4.953ArgVal: 4.953 ± 0.52
2.752ArgTrp: 2.752 ± 0.779
4.403ArgTyr: 4.403 ± 0.766
0.0ArgXaa: 0.0 ± 0.0
Ser
2.477SerAla: 2.477 ± 0.816
1.376SerCys: 1.376 ± 1.015
2.477SerAsp: 2.477 ± 0.792
3.577SerGlu: 3.577 ± 0.833
1.101SerPhe: 1.101 ± 0.474
4.953SerGly: 4.953 ± 1.92
1.376SerHis: 1.376 ± 0.669
2.752SerIle: 2.752 ± 0.693
3.853SerLys: 3.853 ± 1.389
3.302SerLeu: 3.302 ± 0.422
0.275SerMet: 0.275 ± 0.519
3.027SerAsn: 3.027 ± 1.208
4.953SerPro: 4.953 ± 1.287
2.477SerGln: 2.477 ± 1.177
1.376SerArg: 1.376 ± 0.663
3.577SerSer: 3.577 ± 1.414
3.577SerThr: 3.577 ± 1.503
2.752SerVal: 2.752 ± 0.605
1.101SerTrp: 1.101 ± 0.567
0.55SerTyr: 0.55 ± 0.509
0.0SerXaa: 0.0 ± 0.0
Thr
5.228ThrAla: 5.228 ± 0.852
0.826ThrCys: 0.826 ± 0.598
2.752ThrAsp: 2.752 ± 0.669
3.577ThrGlu: 3.577 ± 0.635
2.201ThrPhe: 2.201 ± 1.283
4.403ThrGly: 4.403 ± 1.48
1.101ThrHis: 1.101 ± 0.679
2.201ThrIle: 2.201 ± 0.901
2.752ThrLys: 2.752 ± 0.796
7.155ThrLeu: 7.155 ± 1.221
0.826ThrMet: 0.826 ± 0.562
1.926ThrAsn: 1.926 ± 0.831
4.403ThrPro: 4.403 ± 0.845
2.201ThrGln: 2.201 ± 0.721
1.926ThrArg: 1.926 ± 1.016
1.926ThrSer: 1.926 ± 0.952
4.403ThrThr: 4.403 ± 1.015
3.853ThrVal: 3.853 ± 0.759
1.101ThrTrp: 1.101 ± 0.463
2.201ThrTyr: 2.201 ± 0.541
0.0ThrXaa: 0.0 ± 0.0
Val
2.477ValAla: 2.477 ± 0.66
1.926ValCys: 1.926 ± 0.663
4.403ValAsp: 4.403 ± 1.335
3.027ValGlu: 3.027 ± 1.127
1.376ValPhe: 1.376 ± 0.563
3.853ValGly: 3.853 ± 1.133
1.651ValHis: 1.651 ± 0.752
2.201ValIle: 2.201 ± 0.639
3.302ValLys: 3.302 ± 0.778
6.604ValLeu: 6.604 ± 1.477
0.826ValMet: 0.826 ± 0.34
2.752ValAsn: 2.752 ± 0.781
3.577ValPro: 3.577 ± 1.833
2.477ValGln: 2.477 ± 0.729
2.201ValArg: 2.201 ± 0.425
4.128ValSer: 4.128 ± 1.33
3.577ValThr: 3.577 ± 0.786
3.027ValVal: 3.027 ± 1.219
2.477ValTrp: 2.477 ± 0.542
1.101ValTyr: 1.101 ± 0.495
0.0ValXaa: 0.0 ± 0.0
Trp
2.752TrpAla: 2.752 ± 1.148
0.0TrpCys: 0.0 ± 0.0
1.101TrpAsp: 1.101 ± 0.733
1.651TrpGlu: 1.651 ± 0.391
0.826TrpPhe: 0.826 ± 0.763
2.477TrpGly: 2.477 ± 1.023
0.826TrpHis: 0.826 ± 0.598
1.376TrpIle: 1.376 ± 0.859
2.201TrpLys: 2.201 ± 0.466
1.651TrpLeu: 1.651 ± 0.701
0.55TrpMet: 0.55 ± 0.408
1.376TrpAsn: 1.376 ± 0.539
0.55TrpPro: 0.55 ± 0.24
1.101TrpGln: 1.101 ± 0.567
2.752TrpArg: 2.752 ± 0.506
1.376TrpSer: 1.376 ± 0.552
2.752TrpThr: 2.752 ± 1.042
2.477TrpVal: 2.477 ± 0.798
0.0TrpTrp: 0.0 ± 0.0
0.275TrpTyr: 0.275 ± 0.354
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.376TyrAla: 1.376 ± 1.012
0.55TyrCys: 0.55 ± 0.509
1.101TyrAsp: 1.101 ± 0.286
0.55TyrGlu: 0.55 ± 0.367
0.55TyrPhe: 0.55 ± 0.24
1.376TyrGly: 1.376 ± 0.391
1.101TyrHis: 1.101 ± 0.286
1.101TyrIle: 1.101 ± 1.018
1.101TyrLys: 1.101 ± 0.495
3.027TyrLeu: 3.027 ± 1.001
0.275TyrMet: 0.275 ± 0.183
1.376TyrAsn: 1.376 ± 0.663
3.302TyrPro: 3.302 ± 1.16
1.376TyrGln: 1.376 ± 0.503
1.926TyrArg: 1.926 ± 0.84
1.101TyrSer: 1.101 ± 0.664
1.651TyrThr: 1.651 ± 0.637
0.55TyrVal: 0.55 ± 0.367
1.101TyrTrp: 1.101 ± 0.286
0.55TyrTyr: 0.55 ± 0.24
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (3635 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski