Amino acid dipepetide frequency for Mycetohabitans rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454) (Paraburkholderia rhizoxinica)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.76AlaAla: 15.76 ± 0.194	1.718AlaCys: 1.718 ± 0.043	6.319AlaAsp: 6.319 ± 0.076	5.292AlaGlu: 5.292 ± 0.077	3.759AlaPhe: 3.759 ± 0.056	9.388AlaGly: 9.388 ± 0.134	3.308AlaHis: 3.308 ± 0.073	5.315AlaIle: 5.315 ± 0.07	3.432AlaLys: 3.432 ± 0.071	14.43AlaLeu: 14.43 ± 0.157	3.251AlaMet: 3.251 ± 0.053	3.101AlaAsn: 3.101 ± 0.057	5.908AlaPro: 5.908 ± 0.091	6.628AlaGln: 6.628 ± 0.123	9.859AlaArg: 9.859 ± 0.125	7.294AlaSer: 7.294 ± 0.107	6.115AlaThr: 6.115 ± 0.08	7.85AlaVal: 7.85 ± 0.093	1.733AlaTrp: 1.733 ± 0.048	2.868AlaTyr: 2.868 ± 0.058	0.005AlaXaa: 0.005 ± 0.002
Cys	1.571CysAla: 1.571 ± 0.043	0.229CysCys: 0.229 ± 0.014	0.704CysAsp: 0.704 ± 0.028	0.543CysGlu: 0.543 ± 0.024	0.428CysPhe: 0.428 ± 0.02	1.178CysGly: 1.178 ± 0.034	0.357CysHis: 0.357 ± 0.02	0.483CysIle: 0.483 ± 0.02	0.262CysLys: 0.262 ± 0.017	0.958CysLeu: 0.958 ± 0.032	0.238CysMet: 0.238 ± 0.013	0.281CysAsn: 0.281 ± 0.017	0.622CysPro: 0.622 ± 0.028	0.385CysGln: 0.385 ± 0.021	0.992CysArg: 0.992 ± 0.034	0.724CysSer: 0.724 ± 0.025	0.613CysThr: 0.613 ± 0.024	0.969CysVal: 0.969 ± 0.033	0.17CysTrp: 0.17 ± 0.012	0.299CysTyr: 0.299 ± 0.017	0.001CysXaa: 0.001 ± 0.001
Asp	8.099AspAla: 8.099 ± 0.122	0.516AspCys: 0.516 ± 0.023	3.17AspAsp: 3.17 ± 0.066	3.535AspGlu: 3.535 ± 0.065	1.791AspPhe: 1.791 ± 0.042	4.449AspGly: 4.449 ± 0.065	1.122AspHis: 1.122 ± 0.034	2.479AspIle: 2.479 ± 0.056	1.767AspLys: 1.767 ± 0.053	4.716AspLeu: 4.716 ± 0.074	1.135AspMet: 1.135 ± 0.037	1.44AspAsn: 1.44 ± 0.047	3.006AspPro: 3.006 ± 0.058	1.597AspGln: 1.597 ± 0.036	3.329AspArg: 3.329 ± 0.055	2.472AspSer: 2.472 ± 0.054	2.961AspThr: 2.961 ± 0.05	4.179AspVal: 4.179 ± 0.065	0.899AspTrp: 0.899 ± 0.032	1.596AspTyr: 1.596 ± 0.04	0.002AspXaa: 0.002 ± 0.001
Glu	5.875GluAla: 5.875 ± 0.089	0.457GluCys: 0.457 ± 0.02	1.913GluAsp: 1.913 ± 0.046	1.839GluGlu: 1.839 ± 0.052	1.576GluPhe: 1.576 ± 0.044	2.884GluGly: 2.884 ± 0.053	1.647GluHis: 1.647 ± 0.041	2.645GluIle: 2.645 ± 0.047	1.657GluLys: 1.657 ± 0.046	5.655GluLeu: 5.655 ± 0.092	1.113GluMet: 1.113 ± 0.033	1.22GluAsn: 1.22 ± 0.034	2.783GluPro: 2.783 ± 0.058	3.087GluGln: 3.087 ± 0.065	5.308GluArg: 5.308 ± 0.079	2.365GluSer: 2.365 ± 0.054	2.438GluThr: 2.438 ± 0.054	3.229GluVal: 3.229 ± 0.073	0.62GluTrp: 0.62 ± 0.026	1.179GluTyr: 1.179 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	4.013PheAla: 4.013 ± 0.063	0.475PheCys: 0.475 ± 0.021	2.682PheAsp: 2.682 ± 0.05	1.996PheGlu: 1.996 ± 0.043	1.374PhePhe: 1.374 ± 0.042	3.041PheGly: 3.041 ± 0.058	0.666PheHis: 0.666 ± 0.027	1.527PheIle: 1.527 ± 0.042	1.04PheLys: 1.04 ± 0.032	2.424PheLeu: 2.424 ± 0.054	0.769PheMet: 0.769 ± 0.028	1.141PheAsn: 1.141 ± 0.037	1.304PhePro: 1.304 ± 0.038	0.885PheGln: 0.885 ± 0.026	1.915PheArg: 1.915 ± 0.038	2.201PheSer: 2.201 ± 0.052	1.666PheThr: 1.666 ± 0.041	2.813PheVal: 2.813 ± 0.05	0.427PheTrp: 0.427 ± 0.022	0.865PheTyr: 0.865 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	8.635GlyAla: 8.635 ± 0.119	0.921GlyCys: 0.921 ± 0.035	3.764GlyAsp: 3.764 ± 0.066	4.128GlyGlu: 4.128 ± 0.079	2.761GlyPhe: 2.761 ± 0.063	5.885GlyGly: 5.885 ± 0.107	1.984GlyHis: 1.984 ± 0.048	3.763GlyIle: 3.763 ± 0.075	2.913GlyLys: 2.913 ± 0.057	7.172GlyLeu: 7.172 ± 0.098	2.123GlyMet: 2.123 ± 0.048	2.158GlyAsn: 2.158 ± 0.057	2.9GlyPro: 2.9 ± 0.056	3.022GlyGln: 3.022 ± 0.067	5.304GlyArg: 5.304 ± 0.077	4.154GlySer: 4.154 ± 0.071	4.234GlyThr: 4.234 ± 0.08	6.27GlyVal: 6.27 ± 0.084	1.201GlyTrp: 1.201 ± 0.037	2.213GlyTyr: 2.213 ± 0.047	0.005GlyXaa: 0.005 ± 0.002
His	3.538HisAla: 3.538 ± 0.059	0.413HisCys: 0.413 ± 0.019	1.526HisAsp: 1.526 ± 0.037	1.332HisGlu: 1.332 ± 0.037	0.906HisPhe: 0.906 ± 0.03	2.359HisGly: 2.359 ± 0.055	0.776HisHis: 0.776 ± 0.031	1.083HisIle: 1.083 ± 0.03	0.585HisLys: 0.585 ± 0.023	2.277HisLeu: 2.277 ± 0.051	0.512HisMet: 0.512 ± 0.022	0.586HisAsn: 0.586 ± 0.023	1.56HisPro: 1.56 ± 0.039	1.008HisGln: 1.008 ± 0.053	2.105HisArg: 2.105 ± 0.045	1.348HisSer: 1.348 ± 0.036	1.276HisThr: 1.276 ± 0.037	1.902HisVal: 1.902 ± 0.046	0.438HisTrp: 0.438 ± 0.022	0.764HisTyr: 0.764 ± 0.029	0.004HisXaa: 0.004 ± 0.002
Ile	6.31IleAla: 6.31 ± 0.099	0.516IleCys: 0.516 ± 0.023	3.523IleAsp: 3.523 ± 0.066	3.473IleGlu: 3.473 ± 0.062	1.28IlePhe: 1.28 ± 0.041	4.402IleGly: 4.402 ± 0.081	1.017IleHis: 1.017 ± 0.032	1.688IleIle: 1.688 ± 0.054	1.57IleLys: 1.57 ± 0.044	3.335IleLeu: 3.335 ± 0.059	0.8IleMet: 0.8 ± 0.029	1.414IleAsn: 1.414 ± 0.038	1.923IlePro: 1.923 ± 0.043	1.48IleGln: 1.48 ± 0.04	2.947IleArg: 2.947 ± 0.055	2.354IleSer: 2.354 ± 0.052	2.415IleThr: 2.415 ± 0.042	4.039IleVal: 4.039 ± 0.065	0.565IleTrp: 0.565 ± 0.024	1.001IleTyr: 1.001 ± 0.033	0.001IleXaa: 0.001 ± 0.001
Lys	3.312LysAla: 3.312 ± 0.077	0.225LysCys: 0.225 ± 0.015	1.348LysAsp: 1.348 ± 0.038	1.355LysGlu: 1.355 ± 0.045	0.807LysPhe: 0.807 ± 0.029	1.964LysGly: 1.964 ± 0.047	0.788LysHis: 0.788 ± 0.031	1.556LysIle: 1.556 ± 0.042	1.301LysLys: 1.301 ± 0.049	3.467LysLeu: 3.467 ± 0.064	0.779LysMet: 0.779 ± 0.032	0.941LysAsn: 0.941 ± 0.038	1.946LysPro: 1.946 ± 0.047	1.482LysGln: 1.482 ± 0.048	2.619LysArg: 2.619 ± 0.059	1.673LysSer: 1.673 ± 0.044	1.846LysThr: 1.846 ± 0.048	2.166LysVal: 2.166 ± 0.058	0.373LysTrp: 0.373 ± 0.019	0.653LysTyr: 0.653 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	13.742LeuAla: 13.742 ± 0.155	1.278LeuCys: 1.278 ± 0.034	6.333LeuAsp: 6.333 ± 0.086	5.019LeuGlu: 5.019 ± 0.08	3.498LeuPhe: 3.498 ± 0.078	7.406LeuGly: 7.406 ± 0.088	2.526LeuHis: 2.526 ± 0.054	4.405LeuIle: 4.405 ± 0.065	3.5LeuLys: 3.5 ± 0.067	9.977LeuLeu: 9.977 ± 0.121	2.114LeuMet: 2.114 ± 0.044	3.061LeuAsn: 3.061 ± 0.058	6.269LeuPro: 6.269 ± 0.104	3.889LeuGln: 3.889 ± 0.056	7.638LeuArg: 7.638 ± 0.106	6.759LeuSer: 6.759 ± 0.088	5.437LeuThr: 5.437 ± 0.082	6.688LeuVal: 6.688 ± 0.096	1.143LeuTrp: 1.143 ± 0.031	2.301LeuTyr: 2.301 ± 0.047	0.002LeuXaa: 0.002 ± 0.001
Met	2.568MetAla: 2.568 ± 0.054	0.23MetCys: 0.23 ± 0.015	0.964MetAsp: 0.964 ± 0.031	0.852MetGlu: 0.852 ± 0.033	0.68MetPhe: 0.68 ± 0.027	1.414MetGly: 1.414 ± 0.042	0.655MetHis: 0.655 ± 0.025	1.051MetIle: 1.051 ± 0.034	0.851MetLys: 0.851 ± 0.034	2.826MetLeu: 2.826 ± 0.054	0.657MetMet: 0.657 ± 0.028	0.828MetAsn: 0.828 ± 0.027	1.622MetPro: 1.622 ± 0.037	1.109MetGln: 1.109 ± 0.033	2.111MetArg: 2.111 ± 0.054	1.673MetSer: 1.673 ± 0.042	1.61MetThr: 1.61 ± 0.034	1.511MetVal: 1.511 ± 0.046	0.201MetTrp: 0.201 ± 0.014	0.428MetTyr: 0.428 ± 0.022	0.003MetXaa: 0.003 ± 0.002
Asn	3.429AsnAla: 3.429 ± 0.063	0.294AsnCys: 0.294 ± 0.02	1.448AsnAsp: 1.448 ± 0.037	1.474AsnGlu: 1.474 ± 0.037	0.874AsnPhe: 0.874 ± 0.029	2.453AsnGly: 2.453 ± 0.056	0.596AsnHis: 0.596 ± 0.024	1.272AsnIle: 1.272 ± 0.035	0.842AsnLys: 0.842 ± 0.036	2.608AsnLeu: 2.608 ± 0.049	0.582AsnMet: 0.582 ± 0.023	0.778AsnAsn: 0.778 ± 0.027	1.789AsnPro: 1.789 ± 0.042	0.996AsnGln: 0.996 ± 0.037	2.096AsnArg: 2.096 ± 0.052	1.238AsnSer: 1.238 ± 0.044	1.527AsnThr: 1.527 ± 0.045	2.133AsnVal: 2.133 ± 0.051	0.429AsnTrp: 0.429 ± 0.019	0.681AsnTyr: 0.681 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	6.802ProAla: 6.802 ± 0.09	0.569ProCys: 0.569 ± 0.026	3.317ProAsp: 3.317 ± 0.071	2.69ProGlu: 2.69 ± 0.059	1.945ProPhe: 1.945 ± 0.041	3.908ProGly: 3.908 ± 0.06	1.409ProHis: 1.409 ± 0.036	2.261ProIle: 2.261 ± 0.048	1.45ProLys: 1.45 ± 0.047	5.5ProLeu: 5.5 ± 0.111	1.211ProMet: 1.211 ± 0.037	1.485ProAsn: 1.485 ± 0.037	2.78ProPro: 2.78 ± 0.069	2.169ProGln: 2.169 ± 0.046	3.454ProArg: 3.454 ± 0.066	3.46ProSer: 3.46 ± 0.061	2.849ProThr: 2.849 ± 0.051	4.303ProVal: 4.303 ± 0.062	0.658ProTrp: 0.658 ± 0.027	1.217ProTyr: 1.217 ± 0.031	0.003ProXaa: 0.003 ± 0.001
Gln	5.63GlnAla: 5.63 ± 0.104	0.448GlnCys: 0.448 ± 0.023	1.668GlnAsp: 1.668 ± 0.047	1.475GlnGlu: 1.475 ± 0.046	1.312GlnPhe: 1.312 ± 0.039	2.516GlnGly: 2.516 ± 0.052	1.292GlnHis: 1.292 ± 0.034	2.06GlnIle: 2.06 ± 0.051	1.122GlnLys: 1.122 ± 0.032	4.705GlnLeu: 4.705 ± 0.097	1.073GlnMet: 1.073 ± 0.033	0.897GlnAsn: 0.897 ± 0.03	2.537GlnPro: 2.537 ± 0.06	2.507GlnGln: 2.507 ± 0.077	4.022GlnArg: 4.022 ± 0.069	2.267GlnSer: 2.267 ± 0.053	2.112GlnThr: 2.112 ± 0.049	3.042GlnVal: 3.042 ± 0.085	0.838GlnTrp: 0.838 ± 0.026	1.114GlnTyr: 1.114 ± 0.037	0.002GlnXaa: 0.002 ± 0.001
Arg	9.205ArgAla: 9.205 ± 0.13	1.115ArgCys: 1.115 ± 0.039	4.19ArgAsp: 4.19 ± 0.07	4.108ArgGlu: 4.108 ± 0.079	2.785ArgPhe: 2.785 ± 0.056	5.074ArgGly: 5.074 ± 0.075	2.492ArgHis: 2.492 ± 0.053	3.939ArgIle: 3.939 ± 0.06	2.032ArgLys: 2.032 ± 0.062	8.292ArgLeu: 8.292 ± 0.114	2.021ArgMet: 2.021 ± 0.044	2.077ArgAsn: 2.077 ± 0.038	3.493ArgPro: 3.493 ± 0.058	3.283ArgGln: 3.283 ± 0.061	6.77ArgArg: 6.77 ± 0.121	3.836ArgSer: 3.836 ± 0.069	3.717ArgThr: 3.717 ± 0.061	5.713ArgVal: 5.713 ± 0.085	1.213ArgTrp: 1.213 ± 0.036	2.229ArgTyr: 2.229 ± 0.043	0.005ArgXaa: 0.005 ± 0.002
Ser	6.799SerAla: 6.799 ± 0.092	0.657SerCys: 0.657 ± 0.023	2.898SerAsp: 2.898 ± 0.049	2.594SerGlu: 2.594 ± 0.049	1.905SerPhe: 1.905 ± 0.042	5.031SerGly: 5.031 ± 0.08	1.463SerHis: 1.463 ± 0.029	2.768SerIle: 2.768 ± 0.054	1.563SerLys: 1.563 ± 0.044	5.564SerLeu: 5.564 ± 0.094	1.547SerMet: 1.547 ± 0.043	1.627SerAsn: 1.627 ± 0.044	2.947SerPro: 2.947 ± 0.06	1.987SerGln: 1.987 ± 0.047	4.356SerArg: 4.356 ± 0.081	3.463SerSer: 3.463 ± 0.085	3.201SerThr: 3.201 ± 0.062	4.254SerVal: 4.254 ± 0.062	0.697SerTrp: 0.697 ± 0.029	1.339SerTyr: 1.339 ± 0.037	0.004SerXaa: 0.004 ± 0.002
Thr	5.486ThrAla: 5.486 ± 0.065	0.551ThrCys: 0.551 ± 0.023	2.691ThrAsp: 2.691 ± 0.056	2.235ThrGlu: 2.235 ± 0.05	1.716ThrPhe: 1.716 ± 0.041	4.355ThrGly: 4.355 ± 0.073	1.382ThrHis: 1.382 ± 0.037	2.581ThrIle: 2.581 ± 0.056	1.152ThrLys: 1.152 ± 0.035	6.804ThrLeu: 6.804 ± 0.105	1.231ThrMet: 1.231 ± 0.036	1.228ThrAsn: 1.228 ± 0.041	3.666ThrPro: 3.666 ± 0.07	2.214ThrGln: 2.214 ± 0.049	3.828ThrArg: 3.828 ± 0.067	2.902ThrSer: 2.902 ± 0.058	2.829ThrThr: 2.829 ± 0.064	3.997ThrVal: 3.997 ± 0.071	0.642ThrTrp: 0.642 ± 0.029	1.251ThrTyr: 1.251 ± 0.037	0.003ThrXaa: 0.003 ± 0.002
Val	8.605ValAla: 8.605 ± 0.11	0.872ValCys: 0.872 ± 0.031	3.902ValAsp: 3.902 ± 0.064	3.841ValGlu: 3.841 ± 0.064	2.428ValPhe: 2.428 ± 0.056	5.099ValGly: 5.099 ± 0.077	1.703ValHis: 1.703 ± 0.038	3.565ValIle: 3.565 ± 0.067	2.47ValLys: 2.47 ± 0.055	7.65ValLeu: 7.65 ± 0.093	1.777ValMet: 1.777 ± 0.039	2.163ValAsn: 2.163 ± 0.053	4.34ValPro: 4.34 ± 0.075	3.006ValGln: 3.006 ± 0.068	5.379ValArg: 5.379 ± 0.078	4.548ValSer: 4.548 ± 0.058	4.006ValThr: 4.006 ± 0.065	5.555ValVal: 5.555 ± 0.093	0.925ValTrp: 0.925 ± 0.027	1.558ValTyr: 1.558 ± 0.035	0.003ValXaa: 0.003 ± 0.002
Trp	1.16TrpAla: 1.16 ± 0.034	0.183TrpCys: 0.183 ± 0.012	0.557TrpAsp: 0.557 ± 0.026	0.488TrpGlu: 0.488 ± 0.024	0.492TrpPhe: 0.492 ± 0.021	0.72TrpGly: 0.72 ± 0.026	0.474TrpHis: 0.474 ± 0.018	0.691TrpIle: 0.691 ± 0.025	0.411TrpLys: 0.411 ± 0.019	1.925TrpLeu: 1.925 ± 0.046	0.385TrpMet: 0.385 ± 0.021	0.446TrpAsn: 0.446 ± 0.02	0.74TrpPro: 0.74 ± 0.029	0.897TrpGln: 0.897 ± 0.03	1.429TrpArg: 1.429 ± 0.041	0.802TrpSer: 0.802 ± 0.03	0.641TrpThr: 0.641 ± 0.023	0.87TrpVal: 0.87 ± 0.027	0.211TrpTrp: 0.211 ± 0.013	0.296TrpTyr: 0.296 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.791TyrAla: 2.791 ± 0.052	0.338TyrCys: 0.338 ± 0.019	1.345TyrAsp: 1.345 ± 0.036	1.222TyrGlu: 1.222 ± 0.034	0.904TyrPhe: 0.904 ± 0.027	1.982TyrGly: 1.982 ± 0.042	0.641TyrHis: 0.641 ± 0.022	0.92TyrIle: 0.92 ± 0.028	0.677TyrLys: 0.677 ± 0.027	2.695TyrLeu: 2.695 ± 0.056	0.522TyrMet: 0.522 ± 0.025	0.663TyrAsn: 0.663 ± 0.027	1.299TyrPro: 1.299 ± 0.041	1.005TyrGln: 1.005 ± 0.038	2.125TyrArg: 2.125 ± 0.05	1.13TyrSer: 1.13 ± 0.04	1.246TyrThr: 1.246 ± 0.035	1.909TyrVal: 1.909 ± 0.052	0.436TyrTrp: 0.436 ± 0.022	0.649TyrTyr: 0.649 ± 0.027	0.003TyrXaa: 0.003 ± 0.001
Xaa	0.005XaaAla: 0.005 ± 0.002	0.0XaaCys: 0.0 ± 0.0	0.002XaaAsp: 0.002 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.003XaaPhe: 0.003 ± 0.001	0.005XaaGly: 0.005 ± 0.002	0.003XaaHis: 0.003 ± 0.002	0.001XaaIle: 0.001 ± 0.001	0.003XaaLys: 0.003 ± 0.002	0.004XaaLeu: 0.004 ± 0.002	0.0XaaMet: 0.0 ± 0.0	0.002XaaAsn: 0.002 ± 0.001	0.005XaaPro: 0.005 ± 0.002	0.001XaaGln: 0.001 ± 0.001	0.005XaaArg: 0.005 ± 0.002	0.001XaaSer: 0.001 ± 0.001	0.004XaaThr: 0.004 ± 0.002	0.004XaaVal: 0.004 ± 0.002	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.012XaaXaa: 0.012 ± 0.01

Statistics based on 3859 proteins (1108700 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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