Amino acid dipepetide frequency for Niastella koreensis (strain DSM 17620 / KACC 11465 / NBRC 106392 / GR20-10)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.291AlaAla: 7.291 ± 0.066
0.823AlaCys: 0.823 ± 0.018
4.189AlaAsp: 4.189 ± 0.045
3.827AlaGlu: 3.827 ± 0.044
3.461AlaPhe: 3.461 ± 0.037
6.514AlaGly: 6.514 ± 0.059
1.335AlaHis: 1.335 ± 0.029
5.425AlaIle: 5.425 ± 0.05
4.073AlaLys: 4.073 ± 0.047
6.93AlaLeu: 6.93 ± 0.067
1.786AlaMet: 1.786 ± 0.025
4.048AlaAsn: 4.048 ± 0.05
2.706AlaPro: 2.706 ± 0.038
2.995AlaGln: 2.995 ± 0.034
2.968AlaArg: 2.968 ± 0.033
4.661AlaSer: 4.661 ± 0.046
4.947AlaThr: 4.947 ± 0.059
5.069AlaVal: 5.069 ± 0.048
1.024AlaTrp: 1.024 ± 0.021
2.93AlaTyr: 2.93 ± 0.042
0.0AlaXaa: 0.0 ± 0.0
Cys
0.581CysAla: 0.581 ± 0.016
0.145CysCys: 0.145 ± 0.008
0.422CysAsp: 0.422 ± 0.014
0.402CysGlu: 0.402 ± 0.012
0.46CysPhe: 0.46 ± 0.014
0.661CysGly: 0.661 ± 0.018
0.2CysHis: 0.2 ± 0.01
0.685CysIle: 0.685 ± 0.019
0.55CysLys: 0.55 ± 0.015
0.879CysLeu: 0.879 ± 0.02
0.234CysMet: 0.234 ± 0.009
0.484CysAsn: 0.484 ± 0.014
0.38CysPro: 0.38 ± 0.016
0.268CysGln: 0.268 ± 0.009
0.371CysArg: 0.371 ± 0.012
0.603CysSer: 0.603 ± 0.016
0.57CysThr: 0.57 ± 0.017
0.521CysVal: 0.521 ± 0.015
0.128CysTrp: 0.128 ± 0.007
0.398CysTyr: 0.398 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
4.118AspAla: 4.118 ± 0.044
0.425AspCys: 0.425 ± 0.013
2.477AspAsp: 2.477 ± 0.032
2.908AspGlu: 2.908 ± 0.044
2.58AspPhe: 2.58 ± 0.039
3.833AspGly: 3.833 ± 0.046
0.992AspHis: 0.992 ± 0.019
3.477AspIle: 3.477 ± 0.038
3.612AspLys: 3.612 ± 0.043
4.605AspLeu: 4.605 ± 0.05
1.112AspMet: 1.112 ± 0.022
2.912AspAsn: 2.912 ± 0.036
2.218AspPro: 2.218 ± 0.032
1.715AspGln: 1.715 ± 0.023
2.082AspArg: 2.082 ± 0.028
3.15AspSer: 3.15 ± 0.049
2.705AspThr: 2.705 ± 0.032
3.409AspVal: 3.409 ± 0.039
0.827AspTrp: 0.827 ± 0.019
2.515AspTyr: 2.515 ± 0.033
0.0AspXaa: 0.0 ± 0.0
Glu
3.939GluAla: 3.939 ± 0.043
0.361GluCys: 0.361 ± 0.013
2.306GluAsp: 2.306 ± 0.036
3.297GluGlu: 3.297 ± 0.054
2.136GluPhe: 2.136 ± 0.031
3.118GluGly: 3.118 ± 0.036
1.046GluHis: 1.046 ± 0.023
3.571GluIle: 3.571 ± 0.046
4.502GluLys: 4.502 ± 0.06
5.308GluLeu: 5.308 ± 0.062
1.437GluMet: 1.437 ± 0.024
2.818GluAsn: 2.818 ± 0.033
1.685GluPro: 1.685 ± 0.024
2.498GluGln: 2.498 ± 0.037
2.29GluArg: 2.29 ± 0.032
2.467GluSer: 2.467 ± 0.034
2.79GluThr: 2.79 ± 0.037
3.487GluVal: 3.487 ± 0.042
0.703GluTrp: 0.703 ± 0.017
2.014GluTyr: 2.014 ± 0.033
0.0GluXaa: 0.0 ± 0.0
Phe
3.167PheAla: 3.167 ± 0.035
0.484PheCys: 0.484 ± 0.017
2.726PheAsp: 2.726 ± 0.038
2.398PheGlu: 2.398 ± 0.035
2.33PhePhe: 2.33 ± 0.035
3.125PheGly: 3.125 ± 0.041
0.854PheHis: 0.854 ± 0.018
3.307PheIle: 3.307 ± 0.036
2.737PheLys: 2.737 ± 0.033
4.034PheLeu: 4.034 ± 0.05
1.103PheMet: 1.103 ± 0.021
3.026PheAsn: 3.026 ± 0.043
1.757PhePro: 1.757 ± 0.027
1.484PheGln: 1.484 ± 0.026
1.964PheArg: 1.964 ± 0.03
3.473PheSer: 3.473 ± 0.04
3.484PheThr: 3.484 ± 0.038
2.763PheVal: 2.763 ± 0.032
0.594PheTrp: 0.594 ± 0.018
2.113PheTyr: 2.113 ± 0.03
0.0PheXaa: 0.0 ± 0.0
Gly
5.008GlyAla: 5.008 ± 0.058
0.77GlyCys: 0.77 ± 0.021
3.486GlyAsp: 3.486 ± 0.04
3.235GlyGlu: 3.235 ± 0.04
3.473GlyPhe: 3.473 ± 0.043
5.251GlyGly: 5.251 ± 0.077
1.279GlyHis: 1.279 ± 0.025
5.175GlyIle: 5.175 ± 0.048
5.099GlyLys: 5.099 ± 0.051
5.972GlyLeu: 5.972 ± 0.047
1.778GlyMet: 1.778 ± 0.028
4.245GlyAsn: 4.245 ± 0.06
1.767GlyPro: 1.767 ± 0.03
2.384GlyGln: 2.384 ± 0.035
2.795GlyArg: 2.795 ± 0.037
4.632GlySer: 4.632 ± 0.062
4.627GlyThr: 4.627 ± 0.074
4.613GlyVal: 4.613 ± 0.048
1.118GlyTrp: 1.118 ± 0.024
3.308GlyTyr: 3.308 ± 0.043
0.0GlyXaa: 0.0 ± 0.0
His
1.275HisAla: 1.275 ± 0.024
0.212HisCys: 0.212 ± 0.01
0.912HisAsp: 0.912 ± 0.018
0.999HisGlu: 0.999 ± 0.02
1.181HisPhe: 1.181 ± 0.022
1.153HisGly: 1.153 ± 0.022
0.554HisHis: 0.554 ± 0.018
1.413HisIle: 1.413 ± 0.025
0.991HisLys: 0.991 ± 0.023
1.869HisLeu: 1.869 ± 0.029
0.404HisMet: 0.404 ± 0.014
0.996HisAsn: 0.996 ± 0.021
1.061HisPro: 1.061 ± 0.023
0.776HisGln: 0.776 ± 0.017
0.817HisArg: 0.817 ± 0.02
1.096HisSer: 1.096 ± 0.021
1.16HisThr: 1.16 ± 0.021
1.095HisVal: 1.095 ± 0.024
0.304HisTrp: 0.304 ± 0.011
0.919HisTyr: 0.919 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
5.426IleAla: 5.426 ± 0.054
0.706IleCys: 0.706 ± 0.016
4.004IleAsp: 4.004 ± 0.042
3.614IleGlu: 3.614 ± 0.046
2.68IlePhe: 2.68 ± 0.037
4.479IleGly: 4.479 ± 0.049
1.281IleHis: 1.281 ± 0.023
4.54IleIle: 4.54 ± 0.054
4.39IleLys: 4.39 ± 0.043
5.362IleLeu: 5.362 ± 0.062
1.314IleMet: 1.314 ± 0.024
4.006IleAsn: 4.006 ± 0.048
3.067IlePro: 3.067 ± 0.036
2.436IleGln: 2.436 ± 0.034
3.037IleArg: 3.037 ± 0.034
4.536IleSer: 4.536 ± 0.045
4.926IleThr: 4.926 ± 0.047
4.155IleVal: 4.155 ± 0.044
0.748IleTrp: 0.748 ± 0.018
2.509IleTyr: 2.509 ± 0.031
0.0IleXaa: 0.0 ± 0.0
Lys
4.934LysAla: 4.934 ± 0.049
0.349LysCys: 0.349 ± 0.012
3.793LysAsp: 3.793 ± 0.052
4.46LysGlu: 4.46 ± 0.051
2.193LysPhe: 2.193 ± 0.032
4.377LysGly: 4.377 ± 0.039
1.152LysHis: 1.152 ± 0.024
4.099LysIle: 4.099 ± 0.042
5.373LysLys: 5.373 ± 0.07
5.567LysLeu: 5.567 ± 0.046
1.815LysMet: 1.815 ± 0.033
3.752LysAsn: 3.752 ± 0.037
2.691LysPro: 2.691 ± 0.037
2.945LysGln: 2.945 ± 0.038
2.662LysArg: 2.662 ± 0.033
3.302LysSer: 3.302 ± 0.034
3.969LysThr: 3.969 ± 0.038
4.053LysVal: 4.053 ± 0.041
0.872LysTrp: 0.872 ± 0.019
2.665LysTyr: 2.665 ± 0.035
0.0LysXaa: 0.0 ± 0.0
Leu
6.784LeuAla: 6.784 ± 0.067
0.827LeuCys: 0.827 ± 0.02
4.246LeuAsp: 4.246 ± 0.043
4.39LeuGlu: 4.39 ± 0.054
4.687LeuPhe: 4.687 ± 0.047
5.497LeuGly: 5.497 ± 0.048
1.947LeuHis: 1.947 ± 0.031
5.842LeuIle: 5.842 ± 0.068
6.118LeuLys: 6.118 ± 0.058
9.808LeuLeu: 9.808 ± 0.098
2.076LeuMet: 2.076 ± 0.03
5.264LeuAsn: 5.264 ± 0.046
4.445LeuPro: 4.445 ± 0.044
4.652LeuGln: 4.652 ± 0.05
3.777LeuArg: 3.777 ± 0.044
6.244LeuSer: 6.244 ± 0.057
5.761LeuThr: 5.761 ± 0.052
5.716LeuVal: 5.716 ± 0.059
1.006LeuTrp: 1.006 ± 0.024
3.592LeuTyr: 3.592 ± 0.04
0.0LeuXaa: 0.0 ± 0.0
Met
1.948MetAla: 1.948 ± 0.027
0.152MetCys: 0.152 ± 0.007
1.123MetAsp: 1.123 ± 0.022
1.309MetGlu: 1.309 ± 0.024
0.768MetPhe: 0.768 ± 0.018
1.538MetGly: 1.538 ± 0.024
0.508MetHis: 0.508 ± 0.015
1.386MetIle: 1.386 ± 0.027
1.933MetLys: 1.933 ± 0.027
2.149MetLeu: 2.149 ± 0.03
0.584MetMet: 0.584 ± 0.016
1.357MetAsn: 1.357 ± 0.024
1.132MetPro: 1.132 ± 0.021
1.137MetGln: 1.137 ± 0.022
1.074MetArg: 1.074 ± 0.018
1.332MetSer: 1.332 ± 0.024
1.136MetThr: 1.136 ± 0.019
1.513MetVal: 1.513 ± 0.026
0.227MetTrp: 0.227 ± 0.01
0.75MetTyr: 0.75 ± 0.016
0.0MetXaa: 0.0 ± 0.0
Asn
4.146AsnAla: 4.146 ± 0.041
0.507AsnCys: 0.507 ± 0.016
3.055AsnAsp: 3.055 ± 0.032
2.948AsnGlu: 2.948 ± 0.031
2.495AsnPhe: 2.495 ± 0.03
4.58AsnGly: 4.58 ± 0.057
0.965AsnHis: 0.965 ± 0.02
3.985AsnIle: 3.985 ± 0.044
3.661AsnLys: 3.661 ± 0.042
4.652AsnLeu: 4.652 ± 0.049
1.245AsnMet: 1.245 ± 0.023
3.864AsnAsn: 3.864 ± 0.056
2.754AsnPro: 2.754 ± 0.039
2.073AsnGln: 2.073 ± 0.036
2.504AsnArg: 2.504 ± 0.033
3.462AsnSer: 3.462 ± 0.046
3.754AsnThr: 3.754 ± 0.056
3.329AsnVal: 3.329 ± 0.047
0.909AsnTrp: 0.909 ± 0.019
2.74AsnTyr: 2.74 ± 0.039
0.0AsnXaa: 0.0 ± 0.0
Pro
4.115ProAla: 4.115 ± 0.052
0.245ProCys: 0.245 ± 0.009
2.638ProAsp: 2.638 ± 0.03
2.49ProGlu: 2.49 ± 0.037
2.036ProPhe: 2.036 ± 0.027
3.43ProGly: 3.43 ± 0.037
0.735ProHis: 0.735 ± 0.019
2.205ProIle: 2.205 ± 0.031
1.936ProLys: 1.936 ± 0.026
3.591ProLeu: 3.591 ± 0.04
0.806ProMet: 0.806 ± 0.018
2.075ProAsn: 2.075 ± 0.034
1.355ProPro: 1.355 ± 0.027
1.438ProGln: 1.438 ± 0.025
1.263ProArg: 1.263 ± 0.026
2.155ProSer: 2.155 ± 0.031
2.147ProThr: 2.147 ± 0.037
3.981ProVal: 3.981 ± 0.048
0.501ProTrp: 0.501 ± 0.014
1.659ProTyr: 1.659 ± 0.028
0.0ProXaa: 0.0 ± 0.0
Gln
2.953GlnAla: 2.953 ± 0.034
0.297GlnCys: 0.297 ± 0.011
1.584GlnAsp: 1.584 ± 0.022
2.06GlnGlu: 2.06 ± 0.032
1.956GlnPhe: 1.956 ± 0.027
2.167GlnGly: 2.167 ± 0.029
0.934GlnHis: 0.934 ± 0.022
2.22GlnIle: 2.22 ± 0.033
2.645GlnLys: 2.645 ± 0.035
4.587GlnLeu: 4.587 ± 0.047
0.947GlnMet: 0.947 ± 0.018
1.959GlnAsn: 1.959 ± 0.03
1.905GlnPro: 1.905 ± 0.032
2.704GlnGln: 2.704 ± 0.038
1.692GlnArg: 1.692 ± 0.026
2.288GlnSer: 2.288 ± 0.033
2.413GlnThr: 2.413 ± 0.032
2.748GlnVal: 2.748 ± 0.035
0.581GlnTrp: 0.581 ± 0.015
1.802GlnTyr: 1.802 ± 0.024
0.0GlnXaa: 0.0 ± 0.0
Arg
2.521ArgAla: 2.521 ± 0.033
0.301ArgCys: 0.301 ± 0.012
1.995ArgAsp: 1.995 ± 0.034
2.266ArgGlu: 2.266 ± 0.038
2.293ArgPhe: 2.293 ± 0.031
2.198ArgGly: 2.198 ± 0.031
0.799ArgHis: 0.799 ± 0.019
3.088ArgIle: 3.088 ± 0.038
2.935ArgLys: 2.935 ± 0.04
4.143ArgLeu: 4.143 ± 0.046
1.109ArgMet: 1.109 ± 0.021
2.513ArgAsn: 2.513 ± 0.034
1.457ArgPro: 1.457 ± 0.023
1.783ArgGln: 1.783 ± 0.032
1.774ArgArg: 1.774 ± 0.03
2.489ArgSer: 2.489 ± 0.029
2.258ArgThr: 2.258 ± 0.028
2.494ArgVal: 2.494 ± 0.032
0.662ArgTrp: 0.662 ± 0.017
1.98ArgTyr: 1.98 ± 0.028
0.0ArgXaa: 0.0 ± 0.0
Ser
4.682SerAla: 4.682 ± 0.048
0.636SerCys: 0.636 ± 0.017
2.921SerAsp: 2.921 ± 0.034
2.567SerGlu: 2.567 ± 0.038
3.498SerPhe: 3.498 ± 0.039
4.974SerGly: 4.974 ± 0.055
1.104SerHis: 1.104 ± 0.023
4.326SerIle: 4.326 ± 0.04
3.449SerLys: 3.449 ± 0.044
6.114SerLeu: 6.114 ± 0.058
1.404SerMet: 1.404 ± 0.023
3.322SerAsn: 3.322 ± 0.047
2.447SerPro: 2.447 ± 0.036
2.088SerGln: 2.088 ± 0.029
2.469SerArg: 2.469 ± 0.031
3.907SerSer: 3.907 ± 0.044
3.879SerThr: 3.879 ± 0.053
4.174SerVal: 4.174 ± 0.048
0.911SerTrp: 0.911 ± 0.02
2.734SerTyr: 2.734 ± 0.043
0.0SerXaa: 0.0 ± 0.0
Thr
5.392ThrAla: 5.392 ± 0.066
0.507ThrCys: 0.507 ± 0.018
3.483ThrAsp: 3.483 ± 0.037
2.751ThrGlu: 2.751 ± 0.036
2.743ThrPhe: 2.743 ± 0.037
5.747ThrGly: 5.747 ± 0.071
1.101ThrHis: 1.101 ± 0.024
4.668ThrIle: 4.668 ± 0.046
3.055ThrLys: 3.055 ± 0.037
5.563ThrLeu: 5.563 ± 0.048
1.112ThrMet: 1.112 ± 0.021
3.397ThrAsn: 3.397 ± 0.042
3.052ThrPro: 3.052 ± 0.042
2.057ThrGln: 2.057 ± 0.03
2.346ThrArg: 2.346 ± 0.03
3.832ThrSer: 3.832 ± 0.049
4.433ThrThr: 4.433 ± 0.073
4.528ThrVal: 4.528 ± 0.055
0.929ThrTrp: 0.929 ± 0.022
2.514ThrTyr: 2.514 ± 0.034
0.0ThrXaa: 0.0 ± 0.0
Val
4.93ValAla: 4.93 ± 0.049
0.64ValCys: 0.64 ± 0.018
3.188ValAsp: 3.188 ± 0.039
3.134ValGlu: 3.134 ± 0.035
3.115ValPhe: 3.115 ± 0.039
3.597ValGly: 3.597 ± 0.041
1.241ValHis: 1.241 ± 0.023
4.572ValIle: 4.572 ± 0.047
4.369ValLys: 4.369 ± 0.045
6.208ValLeu: 6.208 ± 0.051
1.55ValMet: 1.55 ± 0.025
3.942ValAsn: 3.942 ± 0.046
2.74ValPro: 2.74 ± 0.027
2.585ValGln: 2.585 ± 0.031
2.578ValArg: 2.578 ± 0.031
4.362ValSer: 4.362 ± 0.05
4.621ValThr: 4.621 ± 0.052
4.552ValVal: 4.552 ± 0.051
0.787ValTrp: 0.787 ± 0.02
2.735ValTyr: 2.735 ± 0.036
0.0ValXaa: 0.0 ± 0.0
Trp
0.88TrpAla: 0.88 ± 0.02
0.139TrpCys: 0.139 ± 0.007
0.733TrpAsp: 0.733 ± 0.016
0.705TrpGlu: 0.705 ± 0.018
0.658TrpPhe: 0.658 ± 0.02
0.914TrpGly: 0.914 ± 0.02
0.3TrpHis: 0.3 ± 0.01
0.759TrpIle: 0.759 ± 0.017
0.924TrpLys: 0.924 ± 0.021
1.452TrpLeu: 1.452 ± 0.028
0.409TrpMet: 0.409 ± 0.013
0.814TrpAsn: 0.814 ± 0.02
0.418TrpPro: 0.418 ± 0.015
0.738TrpGln: 0.738 ± 0.017
0.581TrpArg: 0.581 ± 0.017
0.803TrpSer: 0.803 ± 0.018
0.756TrpThr: 0.756 ± 0.021
0.862TrpVal: 0.862 ± 0.02
0.258TrpTrp: 0.258 ± 0.01
0.614TrpTyr: 0.614 ± 0.017
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.912TyrAla: 2.912 ± 0.04
0.415TyrCys: 0.415 ± 0.013
2.389TyrAsp: 2.389 ± 0.036
2.014TyrGlu: 2.014 ± 0.029
2.18TyrPhe: 2.18 ± 0.033
2.863TyrGly: 2.863 ± 0.04
0.859TyrHis: 0.859 ± 0.02
2.47TyrIle: 2.47 ± 0.026
2.672TyrLys: 2.672 ± 0.034
3.885TyrLeu: 3.885 ± 0.039
0.83TyrMet: 0.83 ± 0.016
2.834TyrAsn: 2.834 ± 0.044
1.767TyrPro: 1.767 ± 0.028
1.689TyrGln: 1.689 ± 0.025
2.015TyrArg: 2.015 ± 0.027
2.813TyrSer: 2.813 ± 0.036
2.871TyrThr: 2.871 ± 0.04
2.383TyrVal: 2.383 ± 0.036
0.627TyrTrp: 0.627 ± 0.016
2.118TyrTyr: 2.118 ± 0.033
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7171 proteins (2631446 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski