Amino acid dipepetide frequency for Moritella viscosa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.271AlaAla: 7.271 ± 0.106	0.962AlaCys: 0.962 ± 0.028	4.712AlaAsp: 4.712 ± 0.06	5.398AlaGlu: 5.398 ± 0.07	3.301AlaPhe: 3.301 ± 0.056	5.626AlaGly: 5.626 ± 0.094	1.48AlaHis: 1.48 ± 0.036	6.271AlaIle: 6.271 ± 0.081	5.134AlaLys: 5.134 ± 0.067	9.166AlaLeu: 9.166 ± 0.087	2.385AlaMet: 2.385 ± 0.045	3.835AlaAsn: 3.835 ± 0.062	2.53AlaPro: 2.53 ± 0.049	3.471AlaGln: 3.471 ± 0.056	3.129AlaArg: 3.129 ± 0.056	5.124AlaSer: 5.124 ± 0.066	4.528AlaThr: 4.528 ± 0.058	5.795AlaVal: 5.795 ± 0.075	0.834AlaTrp: 0.834 ± 0.025	2.309AlaTyr: 2.309 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.778CysAla: 0.778 ± 0.026	0.188CysCys: 0.188 ± 0.011	0.671CysAsp: 0.671 ± 0.021	0.553CysGlu: 0.553 ± 0.02	0.502CysPhe: 0.502 ± 0.018	0.81CysGly: 0.81 ± 0.023	0.338CysHis: 0.338 ± 0.018	0.71CysIle: 0.71 ± 0.024	0.514CysLys: 0.514 ± 0.018	0.999CysLeu: 0.999 ± 0.027	0.246CysMet: 0.246 ± 0.014	0.446CysAsn: 0.446 ± 0.018	0.407CysPro: 0.407 ± 0.018	0.444CysGln: 0.444 ± 0.017	0.471CysArg: 0.471 ± 0.018	0.752CysSer: 0.752 ± 0.024	0.496CysThr: 0.496 ± 0.019	0.661CysVal: 0.661 ± 0.021	0.127CysTrp: 0.127 ± 0.01	0.375CysTyr: 0.375 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.391AspAla: 4.391 ± 0.058	0.585AspCys: 0.585 ± 0.022	3.348AspAsp: 3.348 ± 0.059	3.643AspGlu: 3.643 ± 0.055	2.574AspPhe: 2.574 ± 0.046	3.621AspGly: 3.621 ± 0.067	1.102AspHis: 1.102 ± 0.032	4.711AspIle: 4.711 ± 0.062	3.604AspLys: 3.604 ± 0.054	5.232AspLeu: 5.232 ± 0.063	1.475AspMet: 1.475 ± 0.033	3.011AspAsn: 3.011 ± 0.064	1.883AspPro: 1.883 ± 0.038	1.708AspGln: 1.708 ± 0.04	2.031AspArg: 2.031 ± 0.04	3.607AspSer: 3.607 ± 0.069	2.931AspThr: 2.931 ± 0.056	3.932AspVal: 3.932 ± 0.056	0.789AspTrp: 0.789 ± 0.024	2.154AspTyr: 2.154 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.359GluAla: 4.359 ± 0.063	0.476GluCys: 0.476 ± 0.017	2.696GluAsp: 2.696 ± 0.042	3.078GluGlu: 3.078 ± 0.065	2.509GluPhe: 2.509 ± 0.046	3.129GluGly: 3.129 ± 0.056	1.524GluHis: 1.524 ± 0.039	4.034GluIle: 4.034 ± 0.065	3.501GluLys: 3.501 ± 0.055	7.111GluLeu: 7.111 ± 0.08	1.567GluMet: 1.567 ± 0.036	2.764GluAsn: 2.764 ± 0.049	1.735GluPro: 1.735 ± 0.036	3.624GluGln: 3.624 ± 0.063	2.778GluArg: 2.778 ± 0.052	3.62GluSer: 3.62 ± 0.059	2.982GluThr: 2.982 ± 0.052	3.734GluVal: 3.734 ± 0.057	0.699GluTrp: 0.699 ± 0.023	1.825GluTyr: 1.825 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.319PheAla: 3.319 ± 0.058	0.5PheCys: 0.5 ± 0.02	2.746PheAsp: 2.746 ± 0.055	2.313PheGlu: 2.313 ± 0.044	1.68PhePhe: 1.68 ± 0.036	2.924PheGly: 2.924 ± 0.053	0.801PheHis: 0.801 ± 0.024	3.282PheIle: 3.282 ± 0.058	2.319PheLys: 2.319 ± 0.045	3.238PheLeu: 3.238 ± 0.06	1.1PheMet: 1.1 ± 0.03	2.53PheAsn: 2.53 ± 0.054	1.368PhePro: 1.368 ± 0.031	1.25PheGln: 1.25 ± 0.029	1.404PheArg: 1.404 ± 0.031	3.788PheSer: 3.788 ± 0.053	2.704PheThr: 2.704 ± 0.051	2.725PheVal: 2.725 ± 0.047	0.512PheTrp: 0.512 ± 0.019	1.422PheTyr: 1.422 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	4.682GlyAla: 4.682 ± 0.069	0.884GlyCys: 0.884 ± 0.029	3.585GlyAsp: 3.585 ± 0.072	3.83GlyGlu: 3.83 ± 0.058	3.103GlyPhe: 3.103 ± 0.05	4.324GlyGly: 4.324 ± 0.074	1.495GlyHis: 1.495 ± 0.034	4.979GlyIle: 4.979 ± 0.066	3.917GlyLys: 3.917 ± 0.059	6.877GlyLeu: 6.877 ± 0.083	1.889GlyMet: 1.889 ± 0.045	2.714GlyAsn: 2.714 ± 0.063	1.478GlyPro: 1.478 ± 0.036	2.5GlyGln: 2.5 ± 0.05	2.682GlyArg: 2.682 ± 0.044	4.059GlySer: 4.059 ± 0.065	3.198GlyThr: 3.198 ± 0.05	4.641GlyVal: 4.641 ± 0.069	0.804GlyTrp: 0.804 ± 0.027	2.528GlyTyr: 2.528 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.548HisAla: 1.548 ± 0.036	0.332HisCys: 0.332 ± 0.015	1.233HisAsp: 1.233 ± 0.032	1.13HisGlu: 1.13 ± 0.028	1.018HisPhe: 1.018 ± 0.03	1.37HisGly: 1.37 ± 0.038	0.63HisHis: 0.63 ± 0.029	1.478HisIle: 1.478 ± 0.032	1.135HisLys: 1.135 ± 0.026	2.101HisLeu: 2.101 ± 0.04	0.491HisMet: 0.491 ± 0.018	1.076HisAsn: 1.076 ± 0.03	0.971HisPro: 0.971 ± 0.029	1.053HisGln: 1.053 ± 0.031	0.899HisArg: 0.899 ± 0.026	1.347HisSer: 1.347 ± 0.032	1.044HisThr: 1.044 ± 0.028	1.312HisVal: 1.312 ± 0.035	0.328HisTrp: 0.328 ± 0.015	0.887HisTyr: 0.887 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.743IleAla: 6.743 ± 0.078	0.75IleCys: 0.75 ± 0.026	4.595IleAsp: 4.595 ± 0.068	4.737IleGlu: 4.737 ± 0.058	2.667IlePhe: 2.667 ± 0.05	4.696IleGly: 4.696 ± 0.062	1.305IleHis: 1.305 ± 0.033	4.869IleIle: 4.869 ± 0.072	4.244IleLys: 4.244 ± 0.07	6.0IleLeu: 6.0 ± 0.078	1.506IleMet: 1.506 ± 0.033	4.067IleAsn: 4.067 ± 0.062	2.723IlePro: 2.723 ± 0.05	2.369IleGln: 2.369 ± 0.042	2.864IleArg: 2.864 ± 0.049	5.535IleSer: 5.535 ± 0.069	4.622IleThr: 4.622 ± 0.065	4.295IleVal: 4.295 ± 0.063	0.658IleTrp: 0.658 ± 0.022	2.041IleTyr: 2.041 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	4.609LysAla: 4.609 ± 0.079	0.375LysCys: 0.375 ± 0.016	2.874LysAsp: 2.874 ± 0.05	3.101LysGlu: 3.101 ± 0.058	1.879LysPhe: 1.879 ± 0.035	3.327LysGly: 3.327 ± 0.059	1.323LysHis: 1.323 ± 0.034	3.863LysIle: 3.863 ± 0.052	3.446LysLys: 3.446 ± 0.062	6.103LysLeu: 6.103 ± 0.06	1.586LysMet: 1.586 ± 0.034	2.826LysAsn: 2.826 ± 0.054	2.361LysPro: 2.361 ± 0.046	3.197LysGln: 3.197 ± 0.054	2.676LysArg: 2.676 ± 0.047	3.752LysSer: 3.752 ± 0.056	3.223LysThr: 3.223 ± 0.049	4.047LysVal: 4.047 ± 0.053	0.543LysTrp: 0.543 ± 0.023	1.735LysTyr: 1.735 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	9.861LeuAla: 9.861 ± 0.099	1.049LeuCys: 1.049 ± 0.024	5.782LeuAsp: 5.782 ± 0.079	5.506LeuGlu: 5.506 ± 0.077	4.369LeuPhe: 4.369 ± 0.068	6.471LeuGly: 6.471 ± 0.076	2.025LeuHis: 2.025 ± 0.042	6.827LeuIle: 6.827 ± 0.088	5.492LeuLys: 5.492 ± 0.072	11.039LeuLeu: 11.039 ± 0.144	2.636LeuMet: 2.636 ± 0.047	5.103LeuAsn: 5.103 ± 0.066	4.564LeuPro: 4.564 ± 0.066	4.145LeuGln: 4.145 ± 0.064	4.075LeuArg: 4.075 ± 0.062	8.219LeuSer: 8.219 ± 0.091	6.741LeuThr: 6.741 ± 0.081	6.821LeuVal: 6.821 ± 0.083	0.97LeuTrp: 0.97 ± 0.027	2.701LeuTyr: 2.701 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.362MetAla: 2.362 ± 0.041	0.225MetCys: 0.225 ± 0.013	1.302MetAsp: 1.302 ± 0.031	1.086MetGlu: 1.086 ± 0.029	0.946MetPhe: 0.946 ± 0.032	1.635MetGly: 1.635 ± 0.045	0.53MetHis: 0.53 ± 0.024	1.68MetIle: 1.68 ± 0.036	1.456MetLys: 1.456 ± 0.033	2.794MetLeu: 2.794 ± 0.05	0.795MetMet: 0.795 ± 0.025	1.216MetAsn: 1.216 ± 0.033	1.167MetPro: 1.167 ± 0.03	1.185MetGln: 1.185 ± 0.033	1.06MetArg: 1.06 ± 0.027	1.986MetSer: 1.986 ± 0.044	1.741MetThr: 1.741 ± 0.034	1.598MetVal: 1.598 ± 0.039	0.192MetTrp: 0.192 ± 0.012	0.599MetTyr: 0.599 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.738AsnAla: 3.738 ± 0.063	0.512AsnCys: 0.512 ± 0.018	2.834AsnAsp: 2.834 ± 0.054	2.711AsnGlu: 2.711 ± 0.039	1.835AsnPhe: 1.835 ± 0.036	3.121AsnGly: 3.121 ± 0.051	1.001AsnHis: 1.001 ± 0.031	3.788AsnIle: 3.788 ± 0.059	3.21AsnLys: 3.21 ± 0.054	4.456AsnLeu: 4.456 ± 0.058	1.198AsnMet: 1.198 ± 0.03	2.886AsnAsn: 2.886 ± 0.058	2.019AsnPro: 2.019 ± 0.039	2.13AsnGln: 2.13 ± 0.037	2.015AsnArg: 2.015 ± 0.041	3.172AsnSer: 3.172 ± 0.056	2.815AsnThr: 2.815 ± 0.05	3.014AsnVal: 3.014 ± 0.059	0.66AsnTrp: 0.66 ± 0.023	1.627AsnTyr: 1.627 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	2.964ProAla: 2.964 ± 0.049	0.314ProCys: 0.314 ± 0.015	2.187ProAsp: 2.187 ± 0.045	2.796ProGlu: 2.796 ± 0.041	1.58ProPhe: 1.58 ± 0.037	2.031ProGly: 2.031 ± 0.042	0.8ProHis: 0.8 ± 0.026	2.493ProIle: 2.493 ± 0.048	1.972ProLys: 1.972 ± 0.038	3.818ProLeu: 3.818 ± 0.059	0.89ProMet: 0.89 ± 0.026	1.682ProAsn: 1.682 ± 0.036	0.925ProPro: 0.925 ± 0.029	1.497ProGln: 1.497 ± 0.036	1.241ProArg: 1.241 ± 0.035	2.348ProSer: 2.348 ± 0.038	2.097ProThr: 2.097 ± 0.043	2.862ProVal: 2.862 ± 0.051	0.467ProTrp: 0.467 ± 0.019	1.136ProTyr: 1.136 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.113GlnAla: 4.113 ± 0.065	0.407GlnCys: 0.407 ± 0.018	2.16GlnAsp: 2.16 ± 0.044	2.108GlnGlu: 2.108 ± 0.04	1.731GlnPhe: 1.731 ± 0.034	2.801GlnGly: 2.801 ± 0.049	1.173GlnHis: 1.173 ± 0.026	2.69GlnIle: 2.69 ± 0.04	1.973GlnLys: 1.973 ± 0.039	5.313GlnLeu: 5.313 ± 0.068	0.953GlnMet: 0.953 ± 0.029	1.638GlnAsn: 1.638 ± 0.035	1.596GlnPro: 1.596 ± 0.039	3.334GlnGln: 3.334 ± 0.074	2.199GlnArg: 2.199 ± 0.042	2.607GlnSer: 2.607 ± 0.045	2.276GlnThr: 2.276 ± 0.046	3.132GlnVal: 3.132 ± 0.051	0.549GlnTrp: 0.549 ± 0.018	1.388GlnTyr: 1.388 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.943ArgAla: 2.943 ± 0.056	0.459ArgCys: 0.459 ± 0.02	2.309ArgAsp: 2.309 ± 0.044	2.406ArgGlu: 2.406 ± 0.048	2.046ArgPhe: 2.046 ± 0.044	2.293ArgGly: 2.293 ± 0.043	1.016ArgHis: 1.016 ± 0.032	2.995ArgIle: 2.995 ± 0.047	2.27ArgLys: 2.27 ± 0.046	4.636ArgLeu: 4.636 ± 0.07	1.011ArgMet: 1.011 ± 0.027	1.948ArgAsn: 1.948 ± 0.034	1.383ArgPro: 1.383 ± 0.03	1.963ArgGln: 1.963 ± 0.039	1.973ArgArg: 1.973 ± 0.047	2.509ArgSer: 2.509 ± 0.044	2.052ArgThr: 2.052 ± 0.04	2.761ArgVal: 2.761 ± 0.048	0.538ArgTrp: 0.538 ± 0.023	1.67ArgTyr: 1.67 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.589SerAla: 5.589 ± 0.071	0.683SerCys: 0.683 ± 0.023	3.801SerAsp: 3.801 ± 0.064	3.938SerGlu: 3.938 ± 0.059	3.059SerPhe: 3.059 ± 0.046	4.882SerGly: 4.882 ± 0.069	1.513SerHis: 1.513 ± 0.03	4.878SerIle: 4.878 ± 0.066	3.717SerLys: 3.717 ± 0.05	7.382SerLeu: 7.382 ± 0.085	1.803SerMet: 1.803 ± 0.037	3.222SerAsn: 3.222 ± 0.053	2.29SerPro: 2.29 ± 0.04	2.967SerGln: 2.967 ± 0.049	2.769SerArg: 2.769 ± 0.046	4.89SerSer: 4.89 ± 0.064	3.805SerThr: 3.805 ± 0.057	4.701SerVal: 4.701 ± 0.061	0.83SerTrp: 0.83 ± 0.024	2.302SerTyr: 2.302 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.024ThrAla: 5.024 ± 0.062	0.528ThrCys: 0.528 ± 0.019	3.295ThrAsp: 3.295 ± 0.062	3.359ThrGlu: 3.359 ± 0.054	2.248ThrPhe: 2.248 ± 0.04	4.09ThrGly: 4.09 ± 0.055	1.149ThrHis: 1.149 ± 0.028	3.901ThrIle: 3.901 ± 0.064	2.97ThrLys: 2.97 ± 0.058	6.405ThrLeu: 6.405 ± 0.074	1.221ThrMet: 1.221 ± 0.029	2.543ThrAsn: 2.543 ± 0.047	2.571ThrPro: 2.571 ± 0.045	2.424ThrGln: 2.424 ± 0.045	2.159ThrArg: 2.159 ± 0.042	3.777ThrSer: 3.777 ± 0.057	3.291ThrThr: 3.291 ± 0.062	3.888ThrVal: 3.888 ± 0.061	0.662ThrTrp: 0.662 ± 0.024	1.588ThrTyr: 1.588 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	5.858ValAla: 5.858 ± 0.071	0.72ValCys: 0.72 ± 0.023	3.906ValAsp: 3.906 ± 0.059	4.09ValGlu: 4.09 ± 0.059	2.8ValPhe: 2.8 ± 0.052	4.26ValGly: 4.26 ± 0.068	1.118ValHis: 1.118 ± 0.03	5.147ValIle: 5.147 ± 0.061	3.777ValLys: 3.777 ± 0.054	6.671ValLeu: 6.671 ± 0.083	1.839ValMet: 1.839 ± 0.037	3.368ValAsn: 3.368 ± 0.055	2.361ValPro: 2.361 ± 0.045	2.119ValGln: 2.119 ± 0.048	2.549ValArg: 2.549 ± 0.042	4.958ValSer: 4.958 ± 0.062	4.364ValThr: 4.364 ± 0.068	4.787ValVal: 4.787 ± 0.064	0.653ValTrp: 0.653 ± 0.024	1.87ValTyr: 1.87 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.759TrpAla: 0.759 ± 0.026	0.14TrpCys: 0.14 ± 0.009	0.632TrpAsp: 0.632 ± 0.024	0.483TrpGlu: 0.483 ± 0.019	0.549TrpPhe: 0.549 ± 0.021	0.714TrpGly: 0.714 ± 0.028	0.325TrpHis: 0.325 ± 0.016	0.658TrpIle: 0.658 ± 0.023	0.507TrpLys: 0.507 ± 0.02	1.579TrpLeu: 1.579 ± 0.037	0.302TrpMet: 0.302 ± 0.014	0.453TrpAsn: 0.453 ± 0.019	0.385TrpPro: 0.385 ± 0.017	0.892TrpGln: 0.892 ± 0.027	0.617TrpArg: 0.617 ± 0.02	0.719TrpSer: 0.719 ± 0.023	0.495TrpThr: 0.495 ± 0.02	0.709TrpVal: 0.709 ± 0.02	0.165TrpTrp: 0.165 ± 0.01	0.365TrpTyr: 0.365 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.351TyrAla: 2.351 ± 0.041	0.398TyrCys: 0.398 ± 0.019	1.667TyrAsp: 1.667 ± 0.036	1.477TyrGlu: 1.477 ± 0.037	1.531TyrPhe: 1.531 ± 0.039	2.044TyrGly: 2.044 ± 0.041	0.735TyrHis: 0.735 ± 0.024	2.032TyrIle: 2.032 ± 0.047	1.689TyrLys: 1.689 ± 0.037	3.473TyrLeu: 3.473 ± 0.055	0.661TyrMet: 0.661 ± 0.021	1.414TyrAsn: 1.414 ± 0.034	1.385TyrPro: 1.385 ± 0.036	1.869TyrGln: 1.869 ± 0.042	1.588TyrArg: 1.588 ± 0.036	2.25TyrSer: 2.25 ± 0.05	1.69TyrThr: 1.69 ± 0.043	1.801TyrVal: 1.801 ± 0.034	0.47TyrTrp: 0.47 ± 0.019	1.138TyrTyr: 1.138 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4219 proteins (1380057 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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