Amino acid dipepetide frequency for Bacteroides coprosuis DSM 18011

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.192AlaAla: 4.192 ± 0.091	0.837AlaCys: 0.837 ± 0.031	3.373AlaAsp: 3.373 ± 0.07	4.134AlaGlu: 4.134 ± 0.074	2.867AlaPhe: 2.867 ± 0.054	4.053AlaGly: 4.053 ± 0.077	1.222AlaHis: 1.222 ± 0.036	5.389AlaIle: 5.389 ± 0.099	4.628AlaLys: 4.628 ± 0.071	6.382AlaLeu: 6.382 ± 0.098	1.594AlaMet: 1.594 ± 0.05	3.171AlaAsn: 3.171 ± 0.062	1.908AlaPro: 1.908 ± 0.052	2.59AlaGln: 2.59 ± 0.067	2.407AlaArg: 2.407 ± 0.063	3.99AlaSer: 3.99 ± 0.076	3.338AlaThr: 3.338 ± 0.067	3.875AlaVal: 3.875 ± 0.074	0.617AlaTrp: 0.617 ± 0.026	2.647AlaTyr: 2.647 ± 0.07	0.0AlaXaa: 0.0 ± 0.0
Cys	0.591CysAla: 0.591 ± 0.026	0.145CysCys: 0.145 ± 0.015	0.509CysAsp: 0.509 ± 0.026	0.504CysGlu: 0.504 ± 0.024	0.528CysPhe: 0.528 ± 0.024	0.815CysGly: 0.815 ± 0.032	0.236CysHis: 0.236 ± 0.021	0.86CysIle: 0.86 ± 0.034	0.616CysLys: 0.616 ± 0.028	0.872CysLeu: 0.872 ± 0.032	0.233CysMet: 0.233 ± 0.017	0.466CysAsn: 0.466 ± 0.029	0.432CysPro: 0.432 ± 0.024	0.306CysGln: 0.306 ± 0.018	0.38CysArg: 0.38 ± 0.019	0.796CysSer: 0.796 ± 0.03	0.509CysThr: 0.509 ± 0.025	0.551CysVal: 0.551 ± 0.027	0.089CysTrp: 0.089 ± 0.01	0.386CysTyr: 0.386 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	3.361AspAla: 3.361 ± 0.056	0.48AspCys: 0.48 ± 0.026	2.654AspAsp: 2.654 ± 0.061	4.13AspGlu: 4.13 ± 0.077	3.18AspPhe: 3.18 ± 0.069	3.439AspGly: 3.439 ± 0.069	0.933AspHis: 0.933 ± 0.037	4.737AspIle: 4.737 ± 0.075	4.715AspLys: 4.715 ± 0.072	5.496AspLeu: 5.496 ± 0.071	1.414AspMet: 1.414 ± 0.042	2.887AspAsn: 2.887 ± 0.064	1.859AspPro: 1.859 ± 0.052	1.662AspGln: 1.662 ± 0.047	2.121AspArg: 2.121 ± 0.044	3.296AspSer: 3.296 ± 0.069	2.704AspThr: 2.704 ± 0.053	3.567AspVal: 3.567 ± 0.073	0.731AspTrp: 0.731 ± 0.031	2.779AspTyr: 2.779 ± 0.058	0.0AspXaa: 0.0 ± 0.0
Glu	4.539GluAla: 4.539 ± 0.093	0.507GluCys: 0.507 ± 0.026	3.697GluAsp: 3.697 ± 0.073	5.484GluGlu: 5.484 ± 0.109	2.782GluPhe: 2.782 ± 0.059	4.036GluGly: 4.036 ± 0.072	1.196GluHis: 1.196 ± 0.037	5.114GluIle: 5.114 ± 0.075	5.632GluLys: 5.632 ± 0.098	6.663GluLeu: 6.663 ± 0.097	1.833GluMet: 1.833 ± 0.048	3.975GluAsn: 3.975 ± 0.085	1.682GluPro: 1.682 ± 0.044	2.507GluGln: 2.507 ± 0.052	2.692GluArg: 2.692 ± 0.061	3.802GluSer: 3.802 ± 0.066	3.024GluThr: 3.024 ± 0.067	4.742GluVal: 4.742 ± 0.082	0.796GluTrp: 0.796 ± 0.031	2.879GluTyr: 2.879 ± 0.056	0.0GluXaa: 0.0 ± 0.0
Phe	2.812PheAla: 2.812 ± 0.059	0.499PheCys: 0.499 ± 0.025	2.97PheAsp: 2.97 ± 0.064	2.796PheGlu: 2.796 ± 0.059	2.519PhePhe: 2.519 ± 0.072	3.053PheGly: 3.053 ± 0.065	0.856PheHis: 0.856 ± 0.03	4.009PheIle: 4.009 ± 0.082	3.305PheLys: 3.305 ± 0.067	4.37PheLeu: 4.37 ± 0.079	1.176PheMet: 1.176 ± 0.036	2.759PheAsn: 2.759 ± 0.066	1.619PhePro: 1.619 ± 0.04	1.364PheGln: 1.364 ± 0.041	1.671PheArg: 1.671 ± 0.047	3.49PheSer: 3.49 ± 0.073	2.822PheThr: 2.822 ± 0.06	2.817PheVal: 2.817 ± 0.058	0.492PheTrp: 0.492 ± 0.023	2.092PheTyr: 2.092 ± 0.056	0.0PheXaa: 0.0 ± 0.0
Gly	4.031GlyAla: 4.031 ± 0.076	0.716GlyCys: 0.716 ± 0.035	3.398GlyAsp: 3.398 ± 0.064	3.84GlyGlu: 3.84 ± 0.063	3.146GlyPhe: 3.146 ± 0.065	4.33GlyGly: 4.33 ± 0.085	1.164GlyHis: 1.164 ± 0.039	5.283GlyIle: 5.283 ± 0.087	5.011GlyLys: 5.011 ± 0.078	5.848GlyLeu: 5.848 ± 0.086	1.784GlyMet: 1.784 ± 0.046	3.022GlyAsn: 3.022 ± 0.06	1.25GlyPro: 1.25 ± 0.043	1.78GlyGln: 1.78 ± 0.047	2.262GlyArg: 2.262 ± 0.054	3.876GlySer: 3.876 ± 0.07	3.491GlyThr: 3.491 ± 0.062	4.884GlyVal: 4.884 ± 0.069	0.779GlyTrp: 0.779 ± 0.035	3.034GlyTyr: 3.034 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	1.061HisAla: 1.061 ± 0.035	0.218HisCys: 0.218 ± 0.018	0.859HisAsp: 0.859 ± 0.038	0.997HisGlu: 0.997 ± 0.041	1.114HisPhe: 1.114 ± 0.034	1.103HisGly: 1.103 ± 0.035	0.47HisHis: 0.47 ± 0.023	1.705HisIle: 1.705 ± 0.044	1.294HisLys: 1.294 ± 0.042	1.975HisLeu: 1.975 ± 0.046	0.367HisMet: 0.367 ± 0.019	1.005HisAsn: 1.005 ± 0.036	0.995HisPro: 0.995 ± 0.031	0.755HisGln: 0.755 ± 0.036	0.814HisArg: 0.814 ± 0.034	1.19HisSer: 1.19 ± 0.039	1.059HisThr: 1.059 ± 0.037	0.967HisVal: 0.967 ± 0.034	0.211HisTrp: 0.211 ± 0.015	0.959HisTyr: 0.959 ± 0.039	0.0HisXaa: 0.0 ± 0.0
Ile	5.517IleAla: 5.517 ± 0.079	0.861IleCys: 0.861 ± 0.033	5.171IleAsp: 5.171 ± 0.074	5.554IleGlu: 5.554 ± 0.089	3.137IlePhe: 3.137 ± 0.076	4.869IleGly: 4.869 ± 0.084	1.647IleHis: 1.647 ± 0.051	5.999IleIle: 5.999 ± 0.115	5.49IleLys: 5.49 ± 0.087	7.361IleLeu: 7.361 ± 0.119	1.573IleMet: 1.573 ± 0.046	4.239IleAsn: 4.239 ± 0.079	3.625IlePro: 3.625 ± 0.069	3.16IleGln: 3.16 ± 0.075	2.956IleArg: 2.956 ± 0.058	5.34IleSer: 5.34 ± 0.084	4.442IleThr: 4.442 ± 0.073	4.556IleVal: 4.556 ± 0.085	0.705IleTrp: 0.705 ± 0.031	3.199IleTyr: 3.199 ± 0.067	0.0IleXaa: 0.0 ± 0.0
Lys	5.002LysAla: 5.002 ± 0.085	0.505LysCys: 0.505 ± 0.024	4.821LysAsp: 4.821 ± 0.078	7.012LysGlu: 7.012 ± 0.11	2.523LysPhe: 2.523 ± 0.054	4.779LysGly: 4.779 ± 0.075	1.473LysHis: 1.473 ± 0.041	5.265LysIle: 5.265 ± 0.076	6.112LysLys: 6.112 ± 0.089	6.388LysLeu: 6.388 ± 0.091	2.17LysMet: 2.17 ± 0.054	4.281LysAsn: 4.281 ± 0.069	2.375LysPro: 2.375 ± 0.049	2.769LysGln: 2.769 ± 0.068	3.091LysArg: 3.091 ± 0.06	4.268LysSer: 4.268 ± 0.08	3.903LysThr: 3.903 ± 0.074	4.825LysVal: 4.825 ± 0.08	0.891LysTrp: 0.891 ± 0.036	3.371LysTyr: 3.371 ± 0.076	0.0LysXaa: 0.0 ± 0.0
Leu	6.101LeuAla: 6.101 ± 0.09	1.007LeuCys: 1.007 ± 0.037	5.227LeuAsp: 5.227 ± 0.077	5.921LeuGlu: 5.921 ± 0.082	5.012LeuPhe: 5.012 ± 0.089	5.903LeuGly: 5.903 ± 0.088	1.719LeuHis: 1.719 ± 0.043	6.948LeuIle: 6.948 ± 0.111	7.123LeuLys: 7.123 ± 0.086	9.352LeuLeu: 9.352 ± 0.142	2.354LeuMet: 2.354 ± 0.061	5.389LeuAsn: 5.389 ± 0.079	3.843LeuPro: 3.843 ± 0.068	3.179LeuGln: 3.179 ± 0.062	3.6LeuArg: 3.6 ± 0.071	7.246LeuSer: 7.246 ± 0.101	5.274LeuThr: 5.274 ± 0.077	5.301LeuVal: 5.301 ± 0.091	0.918LeuTrp: 0.918 ± 0.036	3.69LeuTyr: 3.69 ± 0.073	0.0LeuXaa: 0.0 ± 0.0
Met	1.781MetAla: 1.781 ± 0.051	0.198MetCys: 0.198 ± 0.014	1.437MetAsp: 1.437 ± 0.042	1.491MetGlu: 1.491 ± 0.05	0.909MetPhe: 0.909 ± 0.028	1.85MetGly: 1.85 ± 0.055	0.482MetHis: 0.482 ± 0.022	1.658MetIle: 1.658 ± 0.043	2.449MetLys: 2.449 ± 0.046	2.161MetLeu: 2.161 ± 0.05	0.675MetMet: 0.675 ± 0.031	1.537MetAsn: 1.537 ± 0.047	0.984MetPro: 0.984 ± 0.039	0.872MetGln: 0.872 ± 0.031	1.061MetArg: 1.061 ± 0.034	1.448MetSer: 1.448 ± 0.042	1.288MetThr: 1.288 ± 0.039	1.421MetVal: 1.421 ± 0.041	0.194MetTrp: 0.194 ± 0.016	0.747MetTyr: 0.747 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.097AsnAla: 3.097 ± 0.066	0.48AsnCys: 0.48 ± 0.026	2.715AsnAsp: 2.715 ± 0.066	3.247AsnGlu: 3.247 ± 0.066	2.505AsnPhe: 2.505 ± 0.062	3.17AsnGly: 3.17 ± 0.063	1.078AsnHis: 1.078 ± 0.035	4.47AsnIle: 4.47 ± 0.082	4.492AsnLys: 4.492 ± 0.077	5.125AsnLeu: 5.125 ± 0.085	1.3AsnMet: 1.3 ± 0.043	3.096AsnAsn: 3.096 ± 0.066	2.578AsnPro: 2.578 ± 0.055	2.218AsnGln: 2.218 ± 0.054	2.391AsnArg: 2.391 ± 0.057	3.358AsnSer: 3.358 ± 0.071	3.003AsnThr: 3.003 ± 0.061	2.965AsnVal: 2.965 ± 0.07	0.708AsnTrp: 0.708 ± 0.029	2.486AsnTyr: 2.486 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	2.135ProAla: 2.135 ± 0.054	0.291ProCys: 0.291 ± 0.017	1.978ProAsp: 1.978 ± 0.043	2.867ProGlu: 2.867 ± 0.06	1.776ProPhe: 1.776 ± 0.048	1.874ProGly: 1.874 ± 0.053	0.793ProHis: 0.793 ± 0.03	3.202ProIle: 3.202 ± 0.059	2.325ProLys: 2.325 ± 0.056	3.235ProLeu: 3.235 ± 0.059	0.815ProMet: 0.815 ± 0.033	2.051ProAsn: 2.051 ± 0.048	0.727ProPro: 0.727 ± 0.036	1.444ProGln: 1.444 ± 0.041	1.146ProArg: 1.146 ± 0.035	2.376ProSer: 2.376 ± 0.053	2.063ProThr: 2.063 ± 0.053	2.057ProVal: 2.057 ± 0.048	0.413ProTrp: 0.413 ± 0.025	1.649ProTyr: 1.649 ± 0.05	0.0ProXaa: 0.0 ± 0.0
Gln	2.254GlnAla: 2.254 ± 0.059	0.226GlnCys: 0.226 ± 0.017	1.746GlnAsp: 1.746 ± 0.053	2.7GlnGlu: 2.7 ± 0.074	1.607GlnPhe: 1.607 ± 0.041	2.051GlnGly: 2.051 ± 0.061	0.605GlnHis: 0.605 ± 0.025	2.85GlnIle: 2.85 ± 0.063	2.715GlnLys: 2.715 ± 0.058	3.566GlnLeu: 3.566 ± 0.082	0.951GlnMet: 0.951 ± 0.028	2.009GlnAsn: 2.009 ± 0.052	1.107GlnPro: 1.107 ± 0.041	1.34GlnGln: 1.34 ± 0.046	1.481GlnArg: 1.481 ± 0.045	2.157GlnSer: 2.157 ± 0.054	1.926GlnThr: 1.926 ± 0.044	2.229GlnVal: 2.229 ± 0.055	0.423GlnTrp: 0.423 ± 0.023	1.472GlnTyr: 1.472 ± 0.043	0.0GlnXaa: 0.0 ± 0.0
Arg	2.255ArgAla: 2.255 ± 0.054	0.311ArgCys: 0.311 ± 0.022	1.956ArgAsp: 1.956 ± 0.052	2.621ArgGlu: 2.621 ± 0.055	1.865ArgPhe: 1.865 ± 0.048	2.343ArgGly: 2.343 ± 0.056	0.691ArgHis: 0.691 ± 0.028	3.316ArgIle: 3.316 ± 0.071	3.271ArgLys: 3.271 ± 0.068	3.59ArgLeu: 3.59 ± 0.076	1.174ArgMet: 1.174 ± 0.038	2.074ArgAsn: 2.074 ± 0.059	1.302ArgPro: 1.302 ± 0.041	1.334ArgGln: 1.334 ± 0.038	1.708ArgArg: 1.708 ± 0.051	2.272ArgSer: 2.272 ± 0.062	1.939ArgThr: 1.939 ± 0.051	2.6ArgVal: 2.6 ± 0.057	0.465ArgTrp: 0.465 ± 0.025	1.772ArgTyr: 1.772 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	3.834SerAla: 3.834 ± 0.072	0.752SerCys: 0.752 ± 0.031	3.513SerAsp: 3.513 ± 0.056	3.803SerGlu: 3.803 ± 0.069	3.751SerPhe: 3.751 ± 0.074	4.238SerGly: 4.238 ± 0.082	1.228SerHis: 1.228 ± 0.039	5.416SerIle: 5.416 ± 0.095	4.641SerLys: 4.641 ± 0.063	6.292SerLeu: 6.292 ± 0.093	1.519SerMet: 1.519 ± 0.043	3.27SerAsn: 3.27 ± 0.066	2.164SerPro: 2.164 ± 0.049	2.294SerGln: 2.294 ± 0.056	2.398SerArg: 2.398 ± 0.06	4.494SerSer: 4.494 ± 0.093	3.461SerThr: 3.461 ± 0.061	4.063SerVal: 4.063 ± 0.073	0.775SerTrp: 0.775 ± 0.034	2.992SerTyr: 2.992 ± 0.071	0.0SerXaa: 0.0 ± 0.0
Thr	3.296ThrAla: 3.296 ± 0.069	0.457ThrCys: 0.457 ± 0.025	3.13ThrAsp: 3.13 ± 0.068	3.056ThrGlu: 3.056 ± 0.057	2.659ThrPhe: 2.659 ± 0.06	3.444ThrGly: 3.444 ± 0.063	1.182ThrHis: 1.182 ± 0.041	4.494ThrIle: 4.494 ± 0.085	3.501ThrLys: 3.501 ± 0.076	5.442ThrLeu: 5.442 ± 0.077	1.007ThrMet: 1.007 ± 0.035	2.626ThrAsn: 2.626 ± 0.057	2.634ThrPro: 2.634 ± 0.054	1.868ThrGln: 1.868 ± 0.055	1.889ThrArg: 1.889 ± 0.045	3.628ThrSer: 3.628 ± 0.066	3.018ThrThr: 3.018 ± 0.059	3.183ThrVal: 3.183 ± 0.071	0.521ThrTrp: 0.521 ± 0.027	2.437ThrTyr: 2.437 ± 0.057	0.0ThrXaa: 0.0 ± 0.0
Val	4.117ValAla: 4.117 ± 0.079	0.781ValCys: 0.781 ± 0.034	3.856ValAsp: 3.856 ± 0.064	4.271ValGlu: 4.271 ± 0.075	2.947ValPhe: 2.947 ± 0.065	4.113ValGly: 4.113 ± 0.072	1.061ValHis: 1.061 ± 0.036	4.648ValIle: 4.648 ± 0.072	4.47ValLys: 4.47 ± 0.079	5.759ValLeu: 5.759 ± 0.092	1.431ValMet: 1.431 ± 0.042	3.255ValAsn: 3.255 ± 0.059	2.107ValPro: 2.107 ± 0.056	1.957ValGln: 1.957 ± 0.047	2.457ValArg: 2.457 ± 0.068	4.236ValSer: 4.236 ± 0.07	3.101ValThr: 3.101 ± 0.062	4.314ValVal: 4.314 ± 0.092	0.612ValTrp: 0.612 ± 0.029	2.406ValTyr: 2.406 ± 0.05	0.0ValXaa: 0.0 ± 0.0
Trp	0.629TrpAla: 0.629 ± 0.027	0.127TrpCys: 0.127 ± 0.013	0.71TrpAsp: 0.71 ± 0.031	0.678TrpGlu: 0.678 ± 0.029	0.468TrpPhe: 0.468 ± 0.027	0.787TrpGly: 0.787 ± 0.036	0.205TrpHis: 0.205 ± 0.016	0.839TrpIle: 0.839 ± 0.031	0.829TrpLys: 0.829 ± 0.031	1.034TrpLeu: 1.034 ± 0.033	0.344TrpMet: 0.344 ± 0.019	0.754TrpAsn: 0.754 ± 0.033	0.201TrpPro: 0.201 ± 0.017	0.38TrpGln: 0.38 ± 0.021	0.472TrpArg: 0.472 ± 0.024	0.647TrpSer: 0.647 ± 0.029	0.573TrpThr: 0.573 ± 0.027	0.746TrpVal: 0.746 ± 0.03	0.135TrpTrp: 0.135 ± 0.013	0.465TrpTyr: 0.465 ± 0.027	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.61TyrAla: 2.61 ± 0.055	0.424TyrCys: 0.424 ± 0.021	2.428TyrAsp: 2.428 ± 0.059	2.475TyrGlu: 2.475 ± 0.051	2.195TyrPhe: 2.195 ± 0.054	2.679TyrGly: 2.679 ± 0.064	0.875TyrHis: 0.875 ± 0.034	3.203TyrIle: 3.203 ± 0.057	3.208TyrLys: 3.208 ± 0.065	4.193TyrLeu: 4.193 ± 0.08	0.928TyrMet: 0.928 ± 0.037	2.613TyrAsn: 2.613 ± 0.07	1.826TyrPro: 1.826 ± 0.051	1.637TyrGln: 1.637 ± 0.049	1.862TyrArg: 1.862 ± 0.052	2.989TyrSer: 2.989 ± 0.075	2.534TyrThr: 2.534 ± 0.058	2.237TyrVal: 2.237 ± 0.058	0.547TyrTrp: 0.547 ± 0.028	2.003TyrTyr: 2.003 ± 0.054	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2385 proteins (839534 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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