Amino acid dipepetide frequency for Phytophthora infestans RNA virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.948AlaAla: 19.948 ± 6.955
0.434AlaCys: 0.434 ± 0.273
5.637AlaAsp: 5.637 ± 1.681
6.938AlaGlu: 6.938 ± 1.877
6.505AlaPhe: 6.505 ± 1.513
9.54AlaGly: 9.54 ± 2.893
3.036AlaHis: 3.036 ± 0.665
3.469AlaIle: 3.469 ± 0.308
3.036AlaLys: 3.036 ± 1.828
10.841AlaLeu: 10.841 ± 1.842
2.168AlaMet: 2.168 ± 1.128
3.469AlaAsn: 3.469 ± 0.315
3.903AlaPro: 3.903 ± 0.588
4.337AlaGln: 4.337 ± 0.862
8.673AlaArg: 8.673 ± 2.346
5.637AlaSer: 5.637 ± 2.304
7.372AlaThr: 7.372 ± 0.904
6.505AlaVal: 6.505 ± 0.357
1.735AlaTrp: 1.735 ± 0.777
3.903AlaTyr: 3.903 ± 0.588
0.0AlaXaa: 0.0 ± 0.0
Cys
0.867CysAla: 0.867 ± 0.077
0.434CysCys: 0.434 ± 0.273
0.434CysAsp: 0.434 ± 0.273
0.867CysGlu: 0.867 ± 0.077
0.434CysPhe: 0.434 ± 0.273
0.867CysGly: 0.867 ± 0.7
0.434CysHis: 0.434 ± 0.35
0.434CysIle: 0.434 ± 0.273
0.0CysLys: 0.0 ± 0.0
0.434CysLeu: 0.434 ± 0.35
0.434CysMet: 0.434 ± 0.273
0.434CysAsn: 0.434 ± 0.273
0.434CysPro: 0.434 ± 0.35
0.434CysGln: 0.434 ± 0.273
0.434CysArg: 0.434 ± 0.273
0.867CysSer: 0.867 ± 0.7
0.0CysThr: 0.0 ± 0.0
0.434CysVal: 0.434 ± 0.35
0.0CysTrp: 0.0 ± 0.0
0.434CysTyr: 0.434 ± 0.35
0.0CysXaa: 0.0 ± 0.0
Asp
5.637AspAla: 5.637 ± 1.681
0.867AspCys: 0.867 ± 0.077
1.735AspAsp: 1.735 ± 0.469
1.301AspGlu: 1.301 ± 0.427
2.168AspPhe: 2.168 ± 1.751
3.469AspGly: 3.469 ± 0.315
0.0AspHis: 0.0 ± 0.0
2.168AspIle: 2.168 ± 1.128
2.168AspLys: 2.168 ± 1.128
2.602AspLeu: 2.602 ± 0.392
1.735AspMet: 1.735 ± 0.331
0.434AspAsn: 0.434 ± 0.273
2.168AspPro: 2.168 ± 0.119
2.602AspGln: 2.602 ± 1.639
3.469AspArg: 3.469 ± 1.562
4.77AspSer: 4.77 ± 0.511
3.036AspThr: 3.036 ± 0.581
3.903AspVal: 3.903 ± 0.658
0.867AspTrp: 0.867 ± 0.077
3.469AspTyr: 3.469 ± 0.939
0.0AspXaa: 0.0 ± 0.0
Glu
6.505GluAla: 6.505 ± 2.227
0.434GluCys: 0.434 ± 0.273
2.602GluAsp: 2.602 ± 0.392
4.337GluGlu: 4.337 ± 0.862
1.301GluPhe: 1.301 ± 0.427
4.337GluGly: 4.337 ± 1.485
1.735GluHis: 1.735 ± 0.154
2.168GluIle: 2.168 ± 1.128
0.867GluLys: 0.867 ± 0.077
5.204GluLeu: 5.204 ± 0.161
1.735GluMet: 1.735 ± 1.401
0.0GluAsn: 0.0 ± 0.0
2.602GluPro: 2.602 ± 0.231
2.602GluGln: 2.602 ± 0.855
4.77GluArg: 4.77 ± 1.359
3.036GluSer: 3.036 ± 0.581
3.036GluThr: 3.036 ± 0.042
5.204GluVal: 5.204 ± 2.655
1.301GluTrp: 1.301 ± 0.196
3.036GluTyr: 3.036 ± 0.581
0.0GluXaa: 0.0 ± 0.0
Phe
2.168PheAla: 2.168 ± 1.128
0.434PheCys: 0.434 ± 0.35
2.602PheAsp: 2.602 ± 1.016
3.036PheGlu: 3.036 ± 1.205
0.0PhePhe: 0.0 ± 0.0
3.469PheGly: 3.469 ± 0.315
1.735PheHis: 1.735 ± 0.469
0.0PheIle: 0.0 ± 0.0
0.434PheLys: 0.434 ± 0.273
2.602PheLeu: 2.602 ± 0.855
0.0PheMet: 0.0 ± 0.0
2.602PheAsn: 2.602 ± 0.392
0.867PhePro: 0.867 ± 0.077
0.867PheGln: 0.867 ± 0.077
1.301PheArg: 1.301 ± 0.427
3.469PheSer: 3.469 ± 2.178
2.168PheThr: 2.168 ± 0.504
2.168PheVal: 2.168 ± 1.128
0.0PheTrp: 0.0 ± 0.0
1.735PheTyr: 1.735 ± 0.154
0.0PheXaa: 0.0 ± 0.0
Gly
4.77GlyAla: 4.77 ± 2.381
1.301GlyCys: 1.301 ± 0.196
2.168GlyAsp: 2.168 ± 0.504
5.637GlyGlu: 5.637 ± 0.189
3.903GlyPhe: 3.903 ± 1.282
6.938GlyGly: 6.938 ± 1.877
1.735GlyHis: 1.735 ± 0.154
2.168GlyIle: 2.168 ± 0.119
4.337GlyLys: 4.337 ± 1.009
7.372GlyLeu: 7.372 ± 0.967
0.867GlyMet: 0.867 ± 0.546
1.735GlyAsn: 1.735 ± 0.154
0.867GlyPro: 0.867 ± 0.546
3.036GlyGln: 3.036 ± 0.665
6.071GlyArg: 6.071 ± 1.331
4.337GlySer: 4.337 ± 0.862
4.337GlyThr: 4.337 ± 1.009
10.408GlyVal: 10.408 ± 0.322
1.301GlyTrp: 1.301 ± 0.196
2.168GlyTyr: 2.168 ± 0.119
0.0GlyXaa: 0.0 ± 0.0
His
3.469HisAla: 3.469 ± 0.308
0.434HisCys: 0.434 ± 0.35
1.301HisAsp: 1.301 ± 0.196
1.735HisGlu: 1.735 ± 0.154
0.434HisPhe: 0.434 ± 0.35
0.867HisGly: 0.867 ± 0.546
0.0HisHis: 0.0 ± 0.0
0.434HisIle: 0.434 ± 0.273
0.434HisLys: 0.434 ± 0.273
3.469HisLeu: 3.469 ± 0.932
0.867HisMet: 0.867 ± 0.7
1.301HisAsn: 1.301 ± 0.196
0.434HisPro: 0.434 ± 0.35
0.867HisGln: 0.867 ± 0.077
1.301HisArg: 1.301 ± 0.196
2.602HisSer: 2.602 ± 0.231
3.903HisThr: 3.903 ± 0.035
3.469HisVal: 3.469 ± 0.308
0.434HisTrp: 0.434 ± 0.273
0.434HisTyr: 0.434 ± 0.35
0.0HisXaa: 0.0 ± 0.0
Ile
5.204IleAla: 5.204 ± 0.161
0.0IleCys: 0.0 ± 0.0
2.602IleAsp: 2.602 ± 0.392
0.434IleGlu: 0.434 ± 0.35
0.867IlePhe: 0.867 ± 0.7
1.735IleGly: 1.735 ± 0.777
1.735IleHis: 1.735 ± 0.154
0.434IleIle: 0.434 ± 0.35
0.434IleLys: 0.434 ± 0.35
4.77IleLeu: 4.77 ± 1.359
0.867IleMet: 0.867 ± 0.077
1.735IleAsn: 1.735 ± 0.777
1.301IlePro: 1.301 ± 0.427
1.301IleGln: 1.301 ± 0.427
2.602IleArg: 2.602 ± 0.392
2.168IleSer: 2.168 ± 0.742
2.168IleThr: 2.168 ± 0.119
2.602IleVal: 2.602 ± 0.855
0.434IleTrp: 0.434 ± 0.273
0.434IleTyr: 0.434 ± 0.35
0.0IleXaa: 0.0 ± 0.0
Lys
3.469LysAla: 3.469 ± 1.555
0.867LysCys: 0.867 ± 0.7
0.434LysAsp: 0.434 ± 0.35
1.735LysGlu: 1.735 ± 0.154
1.301LysPhe: 1.301 ± 0.427
2.602LysGly: 2.602 ± 0.855
0.434LysHis: 0.434 ± 0.35
2.602LysIle: 2.602 ± 0.855
1.735LysLys: 1.735 ± 0.154
2.602LysLeu: 2.602 ± 0.231
0.0LysMet: 0.0 ± 0.0
0.867LysAsn: 0.867 ± 0.077
0.867LysPro: 0.867 ± 0.546
1.735LysGln: 1.735 ± 0.154
4.337LysArg: 4.337 ± 1.632
0.867LysSer: 0.867 ± 0.7
1.301LysThr: 1.301 ± 0.196
1.735LysVal: 1.735 ± 0.154
1.301LysTrp: 1.301 ± 0.427
1.301LysTyr: 1.301 ± 0.427
0.0LysXaa: 0.0 ± 0.0
Leu
8.673LeuAla: 8.673 ± 2.346
0.867LeuCys: 0.867 ± 0.077
6.505LeuAsp: 6.505 ± 1.513
3.469LeuGlu: 3.469 ± 0.932
1.735LeuPhe: 1.735 ± 0.154
4.77LeuGly: 4.77 ± 0.735
3.036LeuHis: 3.036 ± 0.581
3.469LeuIle: 3.469 ± 0.932
2.602LeuLys: 2.602 ± 0.231
6.071LeuLeu: 6.071 ± 0.539
2.602LeuMet: 2.602 ± 1.478
4.337LeuAsn: 4.337 ± 0.385
8.673LeuPro: 8.673 ± 1.1
2.602LeuGln: 2.602 ± 1.639
7.806LeuArg: 7.806 ± 0.553
10.408LeuSer: 10.408 ± 0.946
4.337LeuThr: 4.337 ± 0.862
6.071LeuVal: 6.071 ± 0.539
2.168LeuTrp: 2.168 ± 0.504
1.735LeuTyr: 1.735 ± 0.154
0.0LeuXaa: 0.0 ± 0.0
Met
3.903MetAla: 3.903 ± 0.658
0.0MetCys: 0.0 ± 0.0
0.867MetAsp: 0.867 ± 0.077
1.301MetGlu: 1.301 ± 0.427
0.867MetPhe: 0.867 ± 0.546
1.735MetGly: 1.735 ± 0.154
0.867MetHis: 0.867 ± 0.7
0.867MetIle: 0.867 ± 0.7
0.0MetLys: 0.0 ± 0.0
1.301MetLeu: 1.301 ± 0.82
1.301MetMet: 1.301 ± 0.427
1.735MetAsn: 1.735 ± 1.401
1.735MetPro: 1.735 ± 0.777
0.867MetGln: 0.867 ± 0.546
2.602MetArg: 2.602 ± 0.855
0.867MetSer: 0.867 ± 0.077
1.301MetThr: 1.301 ± 1.051
3.469MetVal: 3.469 ± 0.932
0.434MetTrp: 0.434 ± 0.35
0.867MetTyr: 0.867 ± 0.546
0.0MetXaa: 0.0 ± 0.0
Asn
4.77AsnAla: 4.77 ± 1.758
1.301AsnCys: 1.301 ± 0.196
2.168AsnAsp: 2.168 ± 0.119
0.867AsnGlu: 0.867 ± 0.7
0.0AsnPhe: 0.0 ± 0.0
2.168AsnGly: 2.168 ± 0.504
2.168AsnHis: 2.168 ± 0.504
2.168AsnIle: 2.168 ± 1.128
0.867AsnLys: 0.867 ± 0.7
3.469AsnLeu: 3.469 ± 0.308
1.301AsnMet: 1.301 ± 0.701
0.867AsnAsn: 0.867 ± 0.077
0.867AsnPro: 0.867 ± 0.077
0.434AsnGln: 0.434 ± 0.273
0.867AsnArg: 0.867 ± 0.077
2.168AsnSer: 2.168 ± 0.119
1.735AsnThr: 1.735 ± 0.777
1.735AsnVal: 1.735 ± 0.777
0.434AsnTrp: 0.434 ± 0.35
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.938ProAla: 6.938 ± 1.254
0.434ProCys: 0.434 ± 0.35
1.301ProAsp: 1.301 ± 0.196
3.469ProGlu: 3.469 ± 0.939
2.168ProPhe: 2.168 ± 1.366
3.036ProGly: 3.036 ± 1.205
0.867ProHis: 0.867 ± 0.546
2.602ProIle: 2.602 ± 0.231
1.301ProLys: 1.301 ± 0.196
3.469ProLeu: 3.469 ± 0.939
0.434ProMet: 0.434 ± 0.273
1.735ProAsn: 1.735 ± 0.469
3.903ProPro: 3.903 ± 0.035
0.434ProGln: 0.434 ± 0.273
3.036ProArg: 3.036 ± 0.665
5.204ProSer: 5.204 ± 0.462
3.036ProThr: 3.036 ± 0.042
3.903ProVal: 3.903 ± 0.035
0.434ProTrp: 0.434 ± 0.35
0.434ProTyr: 0.434 ± 0.273
0.0ProXaa: 0.0 ± 0.0
Gln
3.469GlnAla: 3.469 ± 1.562
0.0GlnCys: 0.0 ± 0.0
0.867GlnAsp: 0.867 ± 0.077
1.301GlnGlu: 1.301 ± 0.82
0.434GlnPhe: 0.434 ± 0.35
2.168GlnGly: 2.168 ± 0.742
1.301GlnHis: 1.301 ± 0.82
0.867GlnIle: 0.867 ± 0.077
0.0GlnLys: 0.0 ± 0.0
5.637GlnLeu: 5.637 ± 0.434
0.434GlnMet: 0.434 ± 0.273
0.0GlnAsn: 0.0 ± 0.0
1.301GlnPro: 1.301 ± 0.196
1.301GlnGln: 1.301 ± 0.82
2.168GlnArg: 2.168 ± 0.119
2.602GlnSer: 2.602 ± 0.392
0.867GlnThr: 0.867 ± 0.7
3.469GlnVal: 3.469 ± 0.308
0.867GlnTrp: 0.867 ± 0.077
1.735GlnTyr: 1.735 ± 0.469
0.0GlnXaa: 0.0 ± 0.0
Arg
6.938ArgAla: 6.938 ± 0.616
0.0ArgCys: 0.0 ± 0.0
3.036ArgAsp: 3.036 ± 0.042
6.938ArgGlu: 6.938 ± 1.24
0.867ArgPhe: 0.867 ± 0.077
6.071ArgGly: 6.071 ± 0.707
2.168ArgHis: 2.168 ± 0.119
2.602ArgIle: 2.602 ± 1.016
3.903ArgLys: 3.903 ± 1.282
7.372ArgLeu: 7.372 ± 0.343
3.036ArgMet: 3.036 ± 0.042
1.301ArgAsn: 1.301 ± 0.427
4.337ArgPro: 4.337 ± 2.732
0.0ArgGln: 0.0 ± 0.0
8.239ArgArg: 8.239 ± 0.203
4.337ArgSer: 4.337 ± 0.862
3.903ArgThr: 3.903 ± 0.035
8.673ArgVal: 8.673 ± 0.476
1.301ArgTrp: 1.301 ± 0.196
4.337ArgTyr: 4.337 ± 0.862
0.0ArgXaa: 0.0 ± 0.0
Ser
9.974SerAla: 9.974 ± 2.543
0.867SerCys: 0.867 ± 0.077
5.204SerAsp: 5.204 ± 1.086
4.337SerGlu: 4.337 ± 0.238
3.036SerPhe: 3.036 ± 0.042
4.337SerGly: 4.337 ± 1.009
3.036SerHis: 3.036 ± 0.042
3.036SerIle: 3.036 ± 0.042
1.301SerLys: 1.301 ± 0.196
5.637SerLeu: 5.637 ± 0.434
3.469SerMet: 3.469 ± 0.932
2.168SerAsn: 2.168 ± 0.119
1.735SerPro: 1.735 ± 1.093
3.469SerGln: 3.469 ± 1.555
3.469SerArg: 3.469 ± 0.939
5.637SerSer: 5.637 ± 2.059
4.337SerThr: 4.337 ± 1.009
2.602SerVal: 2.602 ± 0.855
1.301SerTrp: 1.301 ± 0.82
1.301SerTyr: 1.301 ± 0.196
0.0SerXaa: 0.0 ± 0.0
Thr
5.637ThrAla: 5.637 ± 0.434
0.0ThrCys: 0.0 ± 0.0
0.867ThrAsp: 0.867 ± 0.546
2.168ThrGlu: 2.168 ± 0.504
0.434ThrPhe: 0.434 ± 0.273
6.938ThrGly: 6.938 ± 0.007
2.602ThrHis: 2.602 ± 2.101
1.301ThrIle: 1.301 ± 0.427
3.036ThrLys: 3.036 ± 1.828
6.071ThrLeu: 6.071 ± 0.084
1.735ThrMet: 1.735 ± 0.777
0.867ThrAsn: 0.867 ± 0.7
5.204ThrPro: 5.204 ± 0.784
0.434ThrGln: 0.434 ± 0.273
5.204ThrArg: 5.204 ± 1.408
4.77ThrSer: 4.77 ± 1.359
3.036ThrThr: 3.036 ± 0.581
6.505ThrVal: 6.505 ± 0.981
1.301ThrTrp: 1.301 ± 0.427
0.867ThrTyr: 0.867 ± 0.7
0.0ThrXaa: 0.0 ± 0.0
Val
9.107ValAla: 9.107 ± 0.497
0.434ValCys: 0.434 ± 0.35
5.204ValAsp: 5.204 ± 1.408
4.77ValGlu: 4.77 ± 1.758
2.602ValPhe: 2.602 ± 0.855
8.239ValGly: 8.239 ± 0.203
0.867ValHis: 0.867 ± 0.077
1.301ValIle: 1.301 ± 0.196
3.036ValLys: 3.036 ± 0.042
7.372ValLeu: 7.372 ± 0.343
1.301ValMet: 1.301 ± 1.051
2.168ValAsn: 2.168 ± 0.504
4.337ValPro: 4.337 ± 0.385
2.602ValGln: 2.602 ± 1.016
10.408ValArg: 10.408 ± 1.548
3.036ValSer: 3.036 ± 1.828
4.77ValThr: 4.77 ± 0.112
3.469ValVal: 3.469 ± 1.562
1.301ValTrp: 1.301 ± 0.196
3.036ValTyr: 3.036 ± 0.042
0.0ValXaa: 0.0 ± 0.0
Trp
2.168TrpAla: 2.168 ± 0.742
0.0TrpCys: 0.0 ± 0.0
1.735TrpAsp: 1.735 ± 0.777
0.867TrpGlu: 0.867 ± 0.546
1.301TrpPhe: 1.301 ± 0.427
0.434TrpGly: 0.434 ± 0.273
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.867TrpLys: 0.867 ± 0.077
2.602TrpLeu: 2.602 ± 0.392
0.867TrpMet: 0.867 ± 0.077
0.867TrpAsn: 0.867 ± 0.7
0.867TrpPro: 0.867 ± 0.546
0.434TrpGln: 0.434 ± 0.273
1.301TrpArg: 1.301 ± 0.196
0.867TrpSer: 0.867 ± 0.546
0.867TrpThr: 0.867 ± 0.7
0.867TrpVal: 0.867 ± 0.7
0.0TrpTrp: 0.0 ± 0.0
0.867TrpTyr: 0.867 ± 0.7
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.469TyrAla: 3.469 ± 0.308
0.0TyrCys: 0.0 ± 0.0
1.735TyrAsp: 1.735 ± 0.154
1.301TyrGlu: 1.301 ± 0.82
1.301TyrPhe: 1.301 ± 0.196
1.735TyrGly: 1.735 ± 0.469
0.434TyrHis: 0.434 ± 0.273
1.735TyrIle: 1.735 ± 0.469
1.735TyrLys: 1.735 ± 0.777
3.036TyrLeu: 3.036 ± 0.581
1.301TyrMet: 1.301 ± 0.427
1.735TyrAsn: 1.735 ± 0.469
1.735TyrPro: 1.735 ± 0.777
0.434TyrGln: 0.434 ± 0.35
1.301TyrArg: 1.301 ± 1.051
2.602TyrSer: 2.602 ± 1.016
3.469TyrThr: 3.469 ± 0.315
2.168TyrVal: 2.168 ± 0.119
0.867TyrTrp: 0.867 ± 0.546
1.301TyrTyr: 1.301 ± 0.82
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2307 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski