Amino acid dipepetide frequency for Chrysanthemum virus R

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.928AlaAla: 6.928 ± 4.466
2.078AlaCys: 2.078 ± 1.137
2.771AlaAsp: 2.771 ± 1.009
4.503AlaGlu: 4.503 ± 2.454
2.425AlaPhe: 2.425 ± 1.3
6.235AlaGly: 6.235 ± 1.603
1.386AlaHis: 1.386 ± 0.728
5.888AlaIle: 5.888 ± 4.244
6.235AlaLys: 6.235 ± 1.656
6.235AlaLeu: 6.235 ± 1.8
1.039AlaMet: 1.039 ± 1.364
1.732AlaAsn: 1.732 ± 0.581
1.386AlaPro: 1.386 ± 0.728
1.732AlaGln: 1.732 ± 0.581
4.503AlaArg: 4.503 ± 1.86
3.81AlaSer: 3.81 ± 1.975
2.771AlaThr: 2.771 ± 1.057
3.464AlaVal: 3.464 ± 1.042
1.039AlaTrp: 1.039 ± 0.569
1.039AlaTyr: 1.039 ± 0.681
0.0AlaXaa: 0.0 ± 0.0
Cys
2.771CysAla: 2.771 ± 1.135
0.693CysCys: 0.693 ± 0.754
1.039CysAsp: 1.039 ± 0.709
0.693CysGlu: 0.693 ± 0.754
2.425CysPhe: 2.425 ± 0.995
2.771CysGly: 2.771 ± 0.892
0.346CysHis: 0.346 ± 0.831
1.732CysIle: 1.732 ± 0.948
1.732CysLys: 1.732 ± 0.641
2.425CysLeu: 2.425 ± 2.925
0.346CysMet: 0.346 ± 0.854
1.386CysAsn: 1.386 ± 0.656
0.693CysPro: 0.693 ± 0.379
0.0CysGln: 0.0 ± 0.0
0.693CysArg: 0.693 ± 1.064
1.732CysSer: 1.732 ± 0.948
2.425CysThr: 2.425 ± 1.323
2.078CysVal: 2.078 ± 1.574
0.0CysTrp: 0.0 ± 0.0
1.732CysTyr: 1.732 ± 1.446
0.0CysXaa: 0.0 ± 0.0
Asp
1.386AspAla: 1.386 ± 0.565
2.425AspCys: 2.425 ± 1.758
1.386AspAsp: 1.386 ± 0.565
5.196AspGlu: 5.196 ± 1.196
1.732AspPhe: 1.732 ± 0.948
2.771AspGly: 2.771 ± 0.892
1.386AspHis: 1.386 ± 0.708
1.039AspIle: 1.039 ± 0.569
2.078AspLys: 2.078 ± 1.094
3.81AspLeu: 3.81 ± 0.771
1.039AspMet: 1.039 ± 0.548
1.039AspAsn: 1.039 ± 0.569
3.81AspPro: 3.81 ± 0.947
1.386AspGln: 1.386 ± 0.708
3.464AspArg: 3.464 ± 0.672
2.425AspSer: 2.425 ± 1.229
1.386AspThr: 1.386 ± 0.728
3.464AspVal: 3.464 ± 2.068
0.693AspTrp: 0.693 ± 0.593
1.732AspTyr: 1.732 ± 0.641
0.0AspXaa: 0.0 ± 0.0
Glu
6.235GluAla: 6.235 ± 3.892
2.425GluCys: 2.425 ± 1.011
2.771GluAsp: 2.771 ± 2.35
10.738GluGlu: 10.738 ± 3.949
2.078GluPhe: 2.078 ± 1.137
6.581GluGly: 6.581 ± 1.765
1.732GluHis: 1.732 ± 0.948
3.81GluIle: 3.81 ± 1.391
5.542GluLys: 5.542 ± 1.936
7.274GluLeu: 7.274 ± 1.995
2.078GluMet: 2.078 ± 0.758
2.425GluAsn: 2.425 ± 0.9
1.732GluPro: 1.732 ± 0.685
2.078GluGln: 2.078 ± 1.137
4.503GluArg: 4.503 ± 1.201
5.888GluSer: 5.888 ± 0.969
4.157GluThr: 4.157 ± 1.61
5.542GluVal: 5.542 ± 0.873
0.693GluTrp: 0.693 ± 0.379
4.157GluTyr: 4.157 ± 2.786
0.0GluXaa: 0.0 ± 0.0
Phe
3.464PheAla: 3.464 ± 1.379
0.346PheCys: 0.346 ± 0.19
2.078PheAsp: 2.078 ± 1.358
6.581PheGlu: 6.581 ± 2.617
0.693PhePhe: 0.693 ± 0.379
2.771PheGly: 2.771 ± 2.35
1.039PheHis: 1.039 ± 1.609
1.732PheIle: 1.732 ± 0.948
1.732PheLys: 1.732 ± 0.641
6.235PheLeu: 6.235 ± 1.665
0.693PheMet: 0.693 ± 0.379
1.732PheAsn: 1.732 ± 0.948
0.346PhePro: 0.346 ± 0.19
1.039PheGln: 1.039 ± 0.569
3.81PheArg: 3.81 ± 1.297
3.81PheSer: 3.81 ± 1.297
2.771PheThr: 2.771 ± 0.885
2.078PheVal: 2.078 ± 1.361
0.346PheTrp: 0.346 ± 0.19
2.771PheTyr: 2.771 ± 1.136
0.0PheXaa: 0.0 ± 0.0
Gly
3.81GlyAla: 3.81 ± 0.831
1.732GlyCys: 1.732 ± 1.195
4.157GlyAsp: 4.157 ± 0.812
5.196GlyGlu: 5.196 ± 1.042
3.464GlyPhe: 3.464 ± 2.544
4.849GlyGly: 4.849 ± 1.391
1.039GlyHis: 1.039 ± 0.709
3.464GlyIle: 3.464 ± 1.479
4.849GlyLys: 4.849 ± 2.437
3.464GlyLeu: 3.464 ± 1.371
1.386GlyMet: 1.386 ± 0.758
1.386GlyAsn: 1.386 ± 0.565
2.078GlyPro: 2.078 ± 0.842
2.425GlyGln: 2.425 ± 1.854
4.157GlyArg: 4.157 ± 2.332
5.542GlySer: 5.542 ± 2.482
4.849GlyThr: 4.849 ± 0.721
5.888GlyVal: 5.888 ± 1.424
1.732GlyTrp: 1.732 ± 1.001
1.732GlyTyr: 1.732 ± 0.641
0.0GlyXaa: 0.0 ± 0.0
His
0.346HisAla: 0.346 ± 0.19
0.346HisCys: 0.346 ± 0.863
0.693HisAsp: 0.693 ± 0.379
2.078HisGlu: 2.078 ± 0.758
1.039HisPhe: 1.039 ± 0.681
2.425HisGly: 2.425 ± 0.959
0.693HisHis: 0.693 ± 0.379
1.039HisIle: 1.039 ± 0.681
2.425HisLys: 2.425 ± 1.327
2.771HisLeu: 2.771 ± 1.057
0.346HisMet: 0.346 ± 0.78
0.693HisAsn: 0.693 ± 0.593
0.693HisPro: 0.693 ± 0.939
0.693HisGln: 0.693 ± 0.379
1.732HisArg: 1.732 ± 1.877
3.81HisSer: 3.81 ± 1.101
1.732HisThr: 1.732 ± 0.936
1.039HisVal: 1.039 ± 0.569
0.0HisTrp: 0.0 ± 0.0
0.693HisTyr: 0.693 ± 0.379
0.0HisXaa: 0.0 ± 0.0
Ile
4.157IleAla: 4.157 ± 1.617
1.386IleCys: 1.386 ± 0.758
2.078IleAsp: 2.078 ± 0.758
4.503IleGlu: 4.503 ± 1.081
1.386IlePhe: 1.386 ± 0.656
2.771IleGly: 2.771 ± 0.885
1.039IleHis: 1.039 ± 0.711
3.464IleIle: 3.464 ± 2.534
3.81IleLys: 3.81 ± 1.126
4.849IleLeu: 4.849 ± 1.719
0.693IleMet: 0.693 ± 0.379
3.464IleAsn: 3.464 ± 1.733
2.078IlePro: 2.078 ± 1.636
1.386IleGln: 1.386 ± 1.126
2.078IleArg: 2.078 ± 0.465
3.464IleSer: 3.464 ± 0.971
3.464IleThr: 3.464 ± 1.762
3.464IleVal: 3.464 ± 0.999
0.0IleTrp: 0.0 ± 0.0
3.464IleTyr: 3.464 ± 1.312
0.0IleXaa: 0.0 ± 0.0
Lys
3.117LysAla: 3.117 ± 1.448
1.039LysCys: 1.039 ± 0.681
3.464LysAsp: 3.464 ± 1.001
5.542LysGlu: 5.542 ± 1.273
2.425LysPhe: 2.425 ± 1.327
3.464LysGly: 3.464 ± 1.896
2.078LysHis: 2.078 ± 1.137
3.117LysIle: 3.117 ± 0.997
4.849LysLys: 4.849 ± 2.114
5.888LysLeu: 5.888 ± 1.766
1.386LysMet: 1.386 ± 0.571
3.81LysAsn: 3.81 ± 1.488
4.503LysPro: 4.503 ± 0.878
1.386LysGln: 1.386 ± 1.526
3.81LysArg: 3.81 ± 2.213
3.81LysSer: 3.81 ± 1.235
5.542LysThr: 5.542 ± 1.698
4.157LysVal: 4.157 ± 1.206
0.693LysTrp: 0.693 ± 0.379
3.117LysTyr: 3.117 ± 1.16
0.0LysXaa: 0.0 ± 0.0
Leu
6.581LeuAla: 6.581 ± 1.613
2.425LeuCys: 2.425 ± 0.995
4.503LeuAsp: 4.503 ± 1.348
5.888LeuGlu: 5.888 ± 2.278
3.117LeuPhe: 3.117 ± 1.161
5.542LeuGly: 5.542 ± 2.328
3.117LeuHis: 3.117 ± 1.223
6.235LeuIle: 6.235 ± 3.818
7.62LeuLys: 7.62 ± 3.6
6.581LeuLeu: 6.581 ± 1.67
2.771LeuMet: 2.771 ± 0.943
3.117LeuAsn: 3.117 ± 0.925
4.503LeuPro: 4.503 ± 1.795
1.039LeuGln: 1.039 ± 0.548
6.235LeuArg: 6.235 ± 1.57
6.581LeuSer: 6.581 ± 2.203
4.157LeuThr: 4.157 ± 1.388
5.542LeuVal: 5.542 ± 0.876
0.693LeuTrp: 0.693 ± 0.379
3.117LeuTyr: 3.117 ± 1.238
0.0LeuXaa: 0.0 ± 0.0
Met
3.117MetAla: 3.117 ± 1.194
1.039MetCys: 1.039 ± 0.569
1.386MetAsp: 1.386 ± 1.405
1.386MetGlu: 1.386 ± 0.905
0.346MetPhe: 0.346 ± 0.19
1.732MetGly: 1.732 ± 0.641
0.346MetHis: 0.346 ± 0.19
1.386MetIle: 1.386 ± 0.758
0.693MetLys: 0.693 ± 0.379
2.425MetLeu: 2.425 ± 1.715
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.732MetPro: 1.732 ± 0.864
0.346MetGln: 0.346 ± 0.19
3.81MetArg: 3.81 ± 1.391
1.039MetSer: 1.039 ± 0.569
1.039MetThr: 1.039 ± 0.569
1.039MetVal: 1.039 ± 0.711
0.0MetTrp: 0.0 ± 0.0
0.693MetTyr: 0.693 ± 1.345
0.0MetXaa: 0.0 ± 0.0
Asn
3.117AsnAla: 3.117 ± 0.534
2.078AsnCys: 2.078 ± 0.922
0.346AsnAsp: 0.346 ± 0.19
4.503AsnGlu: 4.503 ± 1.599
1.386AsnPhe: 1.386 ± 0.656
3.117AsnGly: 3.117 ± 1.706
1.039AsnHis: 1.039 ± 0.548
1.039AsnIle: 1.039 ± 0.569
3.117AsnLys: 3.117 ± 0.677
3.464AsnLeu: 3.464 ± 1.345
1.732AsnMet: 1.732 ± 1.863
2.078AsnAsn: 2.078 ± 0.758
0.346AsnPro: 0.346 ± 0.19
0.0AsnGln: 0.0 ± 0.0
3.117AsnArg: 3.117 ± 0.884
2.771AsnSer: 2.771 ± 0.827
1.386AsnThr: 1.386 ± 0.565
1.732AsnVal: 1.732 ± 0.948
0.693AsnTrp: 0.693 ± 0.379
2.078AsnTyr: 2.078 ± 0.922
0.0AsnXaa: 0.0 ± 0.0
Pro
1.386ProAla: 1.386 ± 0.758
0.693ProCys: 0.693 ± 0.379
3.81ProAsp: 3.81 ± 0.994
2.425ProGlu: 2.425 ± 0.409
1.732ProPhe: 1.732 ± 0.948
3.81ProGly: 3.81 ± 2.59
1.386ProHis: 1.386 ± 0.708
2.425ProIle: 2.425 ± 1.323
1.732ProLys: 1.732 ± 1.126
2.771ProLeu: 2.771 ± 0.787
0.346ProMet: 0.346 ± 0.19
2.078ProAsn: 2.078 ± 0.926
3.464ProPro: 3.464 ± 1.727
3.81ProGln: 3.81 ± 1.127
1.732ProArg: 1.732 ± 1.419
2.425ProSer: 2.425 ± 0.888
2.425ProThr: 2.425 ± 1.097
0.693ProVal: 0.693 ± 0.754
1.039ProTrp: 1.039 ± 0.711
1.039ProTyr: 1.039 ± 0.569
0.0ProXaa: 0.0 ± 0.0
Gln
0.693GlnAla: 0.693 ± 1.064
0.693GlnCys: 0.693 ± 0.754
1.039GlnAsp: 1.039 ± 0.569
2.425GlnGlu: 2.425 ± 1.327
2.078GlnPhe: 2.078 ± 0.762
2.078GlnGly: 2.078 ± 1.394
0.693GlnHis: 0.693 ± 0.379
2.425GlnIle: 2.425 ± 1.645
1.386GlnLys: 1.386 ± 0.905
1.732GlnLeu: 1.732 ± 0.948
0.0GlnMet: 0.0 ± 0.0
0.693GlnAsn: 0.693 ± 0.379
1.732GlnPro: 1.732 ± 0.755
0.346GlnGln: 0.346 ± 0.19
2.425GlnArg: 2.425 ± 0.959
2.771GlnSer: 2.771 ± 1.517
1.732GlnThr: 1.732 ± 0.581
0.346GlnVal: 0.346 ± 0.854
0.0GlnTrp: 0.0 ± 0.0
0.693GlnTyr: 0.693 ± 0.379
0.0GlnXaa: 0.0 ± 0.0
Arg
6.235ArgAla: 6.235 ± 1.246
2.078ArgCys: 2.078 ± 2.503
3.117ArgAsp: 3.117 ± 2.482
4.157ArgGlu: 4.157 ± 1.0
5.196ArgPhe: 5.196 ± 0.825
3.464ArgGly: 3.464 ± 1.965
2.425ArgHis: 2.425 ± 0.886
1.732ArgIle: 1.732 ± 1.863
4.157ArgLys: 4.157 ± 0.768
5.888ArgLeu: 5.888 ± 1.706
2.771ArgMet: 2.771 ± 1.057
1.732ArgAsn: 1.732 ± 2.34
1.386ArgPro: 1.386 ± 0.954
0.346ArgGln: 0.346 ± 0.19
4.503ArgArg: 4.503 ± 3.694
6.581ArgSer: 6.581 ± 0.761
1.386ArgThr: 1.386 ± 0.905
3.81ArgVal: 3.81 ± 2.819
1.039ArgTrp: 1.039 ± 0.569
2.425ArgTyr: 2.425 ± 1.327
0.0ArgXaa: 0.0 ± 0.0
Ser
4.849SerAla: 4.849 ± 1.914
1.039SerCys: 1.039 ± 0.711
3.117SerAsp: 3.117 ± 0.899
4.503SerGlu: 4.503 ± 1.2
3.464SerPhe: 3.464 ± 1.101
4.157SerGly: 4.157 ± 0.96
2.425SerHis: 2.425 ± 1.796
2.771SerIle: 2.771 ± 1.057
6.581SerLys: 6.581 ± 2.948
6.928SerLeu: 6.928 ± 1.628
1.386SerMet: 1.386 ± 0.565
3.464SerAsn: 3.464 ± 2.413
3.117SerPro: 3.117 ± 1.223
1.732SerGln: 1.732 ± 0.948
5.196SerArg: 5.196 ± 1.714
5.542SerSer: 5.542 ± 1.128
3.81SerThr: 3.81 ± 1.101
5.196SerVal: 5.196 ± 1.611
0.693SerTrp: 0.693 ± 0.379
1.386SerTyr: 1.386 ± 1.972
0.0SerXaa: 0.0 ± 0.0
Thr
2.771ThrAla: 2.771 ± 1.118
1.386ThrCys: 1.386 ± 1.126
1.732ThrAsp: 1.732 ± 0.948
5.196ThrGlu: 5.196 ± 1.88
6.581ThrPhe: 6.581 ± 1.765
4.157ThrGly: 4.157 ± 2.012
1.732ThrHis: 1.732 ± 0.948
2.078ThrIle: 2.078 ± 0.762
1.386ThrLys: 1.386 ± 1.977
6.581ThrLeu: 6.581 ± 2.267
1.732ThrMet: 1.732 ± 0.948
3.464ThrAsn: 3.464 ± 1.395
1.732ThrPro: 1.732 ± 1.722
1.732ThrGln: 1.732 ± 0.641
2.771ThrArg: 2.771 ± 1.128
1.732ThrSer: 1.732 ± 2.649
2.771ThrThr: 2.771 ± 0.798
2.771ThrVal: 2.771 ± 1.009
0.346ThrTrp: 0.346 ± 0.69
1.732ThrTyr: 1.732 ± 0.821
0.0ThrXaa: 0.0 ± 0.0
Val
3.117ValAla: 3.117 ± 1.029
3.117ValCys: 3.117 ± 1.937
2.078ValAsp: 2.078 ± 0.762
3.81ValGlu: 3.81 ± 1.503
2.771ValPhe: 2.771 ± 0.841
2.771ValGly: 2.771 ± 2.208
1.386ValHis: 1.386 ± 0.758
4.157ValIle: 4.157 ± 1.384
2.771ValLys: 2.771 ± 1.057
5.542ValLeu: 5.542 ± 1.625
1.039ValMet: 1.039 ± 0.569
1.386ValAsn: 1.386 ± 0.656
3.117ValPro: 3.117 ± 0.702
3.117ValGln: 3.117 ± 1.16
3.81ValArg: 3.81 ± 1.62
4.503ValSer: 4.503 ± 1.954
4.157ValThr: 4.157 ± 3.156
4.849ValVal: 4.849 ± 3.042
0.693ValTrp: 0.693 ± 0.939
2.771ValTyr: 2.771 ± 1.125
0.0ValXaa: 0.0 ± 0.0
Trp
1.039TrpAla: 1.039 ± 0.711
0.346TrpCys: 0.346 ± 0.19
0.346TrpAsp: 0.346 ± 0.19
0.0TrpGlu: 0.0 ± 0.0
1.039TrpPhe: 1.039 ± 0.681
0.346TrpGly: 0.346 ± 1.034
0.0TrpHis: 0.0 ± 0.0
0.693TrpIle: 0.693 ± 0.379
1.039TrpLys: 1.039 ± 0.569
1.732TrpLeu: 1.732 ± 0.948
0.693TrpMet: 0.693 ± 0.361
1.039TrpAsn: 1.039 ± 0.548
0.346TrpPro: 0.346 ± 0.19
0.0TrpGln: 0.0 ± 0.0
0.346TrpArg: 0.346 ± 0.19
0.346TrpSer: 0.346 ± 0.69
0.693TrpThr: 0.693 ± 0.379
0.693TrpVal: 0.693 ± 0.379
0.0TrpTrp: 0.0 ± 0.0
0.346TrpTyr: 0.346 ± 0.854
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.425TyrAla: 2.425 ± 1.245
0.346TyrCys: 0.346 ± 0.69
1.732TyrAsp: 1.732 ± 0.948
3.117TyrGlu: 3.117 ± 0.534
0.693TyrPhe: 0.693 ± 0.939
1.386TyrGly: 1.386 ± 0.708
0.0TyrHis: 0.0 ± 0.0
2.771TyrIle: 2.771 ± 0.895
3.464TyrLys: 3.464 ± 1.001
2.771TyrLeu: 2.771 ± 1.136
1.732TyrMet: 1.732 ± 1.126
2.425TyrAsn: 2.425 ± 0.773
2.425TyrPro: 2.425 ± 1.323
1.386TyrGln: 1.386 ± 0.656
1.732TyrArg: 1.732 ± 1.445
2.771TyrSer: 2.771 ± 1.703
1.732TyrThr: 1.732 ± 1.034
3.117TyrVal: 3.117 ± 1.363
0.693TyrTrp: 0.693 ± 0.379
2.078TyrTyr: 2.078 ± 1.35
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2888 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski