Amino acid dipepetide frequency for Salinibacterium xinjiangense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.914AlaAla: 17.914 ± 0.193	0.586AlaCys: 0.586 ± 0.029	7.049AlaAsp: 7.049 ± 0.099	7.019AlaGlu: 7.019 ± 0.103	3.84AlaPhe: 3.84 ± 0.066	11.238AlaGly: 11.238 ± 0.135	2.122AlaHis: 2.122 ± 0.051	6.907AlaIle: 6.907 ± 0.104	2.869AlaLys: 2.869 ± 0.075	12.799AlaLeu: 12.799 ± 0.137	2.674AlaMet: 2.674 ± 0.053	2.795AlaAsn: 2.795 ± 0.061	5.68AlaPro: 5.68 ± 0.112	3.547AlaGln: 3.547 ± 0.067	8.022AlaArg: 8.022 ± 0.114	7.89AlaSer: 7.89 ± 0.099	7.819AlaThr: 7.819 ± 0.104	10.809AlaVal: 10.809 ± 0.136	1.638AlaTrp: 1.638 ± 0.05	2.246AlaTyr: 2.246 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.597CysAla: 0.597 ± 0.025	0.045CysCys: 0.045 ± 0.007	0.321CysAsp: 0.321 ± 0.018	0.261CysGlu: 0.261 ± 0.018	0.184CysPhe: 0.184 ± 0.013	0.579CysGly: 0.579 ± 0.025	0.12CysHis: 0.12 ± 0.011	0.215CysIle: 0.215 ± 0.017	0.068CysLys: 0.068 ± 0.008	0.504CysLeu: 0.504 ± 0.025	0.09CysMet: 0.09 ± 0.01	0.125CysAsn: 0.125 ± 0.014	0.283CysPro: 0.283 ± 0.019	0.13CysGln: 0.13 ± 0.013	0.321CysArg: 0.321 ± 0.019	0.359CysSer: 0.359 ± 0.019	0.311CysThr: 0.311 ± 0.02	0.399CysVal: 0.399 ± 0.019	0.063CysTrp: 0.063 ± 0.008	0.12CysTyr: 0.12 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.609AspAla: 7.609 ± 0.105	0.282AspCys: 0.282 ± 0.019	3.995AspAsp: 3.995 ± 0.095	3.89AspGlu: 3.89 ± 0.063	2.025AspPhe: 2.025 ± 0.05	5.539AspGly: 5.539 ± 0.086	1.154AspHis: 1.154 ± 0.036	2.769AspIle: 2.769 ± 0.058	1.15AspLys: 1.15 ± 0.039	6.049AspLeu: 6.049 ± 0.092	0.872AspMet: 0.872 ± 0.035	1.299AspAsn: 1.299 ± 0.039	3.672AspPro: 3.672 ± 0.072	1.627AspGln: 1.627 ± 0.039	4.084AspArg: 4.084 ± 0.088	3.589AspSer: 3.589 ± 0.068	2.986AspThr: 2.986 ± 0.053	5.156AspVal: 5.156 ± 0.074	0.881AspTrp: 0.881 ± 0.033	1.344AspTyr: 1.344 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.099GluAla: 6.099 ± 0.094	0.273GluCys: 0.273 ± 0.016	2.123GluAsp: 2.123 ± 0.051	2.344GluGlu: 2.344 ± 0.063	1.963GluPhe: 1.963 ± 0.051	3.577GluGly: 3.577 ± 0.077	1.283GluHis: 1.283 ± 0.04	2.932GluIle: 2.932 ± 0.064	1.63GluLys: 1.63 ± 0.05	6.849GluLeu: 6.849 ± 0.097	0.953GluMet: 0.953 ± 0.034	1.433GluAsn: 1.433 ± 0.042	2.696GluPro: 2.696 ± 0.053	2.092GluGln: 2.092 ± 0.051	4.113GluArg: 4.113 ± 0.072	3.412GluSer: 3.412 ± 0.058	2.847GluThr: 2.847 ± 0.05	4.326GluVal: 4.326 ± 0.072	0.834GluTrp: 0.834 ± 0.031	1.138GluTyr: 1.138 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	4.356PheAla: 4.356 ± 0.071	0.214PheCys: 0.214 ± 0.016	2.546PheAsp: 2.546 ± 0.046	1.99PheGlu: 1.99 ± 0.052	1.233PhePhe: 1.233 ± 0.039	3.633PheGly: 3.633 ± 0.07	0.559PheHis: 0.559 ± 0.025	1.607PheIle: 1.607 ± 0.044	0.53PheLys: 0.53 ± 0.024	2.948PheLeu: 2.948 ± 0.056	0.529PheMet: 0.529 ± 0.023	0.805PheAsn: 0.805 ± 0.034	1.525PhePro: 1.525 ± 0.046	0.792PheGln: 0.792 ± 0.03	1.799PheArg: 1.799 ± 0.048	2.16PheSer: 2.16 ± 0.053	2.284PheThr: 2.284 ± 0.052	3.065PheVal: 3.065 ± 0.06	0.51PheTrp: 0.51 ± 0.025	0.748PheTyr: 0.748 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	9.827GlyAla: 9.827 ± 0.128	0.579GlyCys: 0.579 ± 0.026	4.783GlyAsp: 4.783 ± 0.079	4.379GlyGlu: 4.379 ± 0.07	3.506GlyPhe: 3.506 ± 0.071	7.138GlyGly: 7.138 ± 0.105	1.765GlyHis: 1.765 ± 0.05	5.357GlyIle: 5.357 ± 0.086	2.419GlyLys: 2.419 ± 0.057	8.735GlyLeu: 8.735 ± 0.119	2.032GlyMet: 2.032 ± 0.043	2.146GlyAsn: 2.146 ± 0.051	3.547GlyPro: 3.547 ± 0.07	2.558GlyGln: 2.558 ± 0.052	5.623GlyArg: 5.623 ± 0.088	5.993GlySer: 5.993 ± 0.09	5.579GlyThr: 5.579 ± 0.096	7.75GlyVal: 7.75 ± 0.099	1.518GlyTrp: 1.518 ± 0.044	2.127GlyTyr: 2.127 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.009HisAla: 2.009 ± 0.048	0.114HisCys: 0.114 ± 0.012	1.262HisAsp: 1.262 ± 0.04	1.116HisGlu: 1.116 ± 0.042	0.595HisPhe: 0.595 ± 0.027	1.841HisGly: 1.841 ± 0.046	0.556HisHis: 0.556 ± 0.026	0.843HisIle: 0.843 ± 0.032	0.336HisLys: 0.336 ± 0.02	1.896HisLeu: 1.896 ± 0.043	0.32HisMet: 0.32 ± 0.018	0.46HisAsn: 0.46 ± 0.021	1.344HisPro: 1.344 ± 0.043	0.503HisGln: 0.503 ± 0.024	1.427HisArg: 1.427 ± 0.04	1.185HisSer: 1.185 ± 0.033	0.974HisThr: 0.974 ± 0.035	1.483HisVal: 1.483 ± 0.038	0.272HisTrp: 0.272 ± 0.017	0.419HisTyr: 0.419 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.631IleAla: 7.631 ± 0.106	0.267IleCys: 0.267 ± 0.019	4.005IleAsp: 4.005 ± 0.061	3.258IleGlu: 3.258 ± 0.064	1.613IlePhe: 1.613 ± 0.048	5.027IleGly: 5.027 ± 0.077	0.847IleHis: 0.847 ± 0.032	2.562IleIle: 2.562 ± 0.057	1.019IleLys: 1.019 ± 0.039	4.347IleLeu: 4.347 ± 0.065	0.767IleMet: 0.767 ± 0.028	1.198IleAsn: 1.198 ± 0.038	2.838IlePro: 2.838 ± 0.057	1.164IleGln: 1.164 ± 0.035	3.075IleArg: 3.075 ± 0.06	3.251IleSer: 3.251 ± 0.06	3.41IleThr: 3.41 ± 0.066	5.301IleVal: 5.301 ± 0.085	0.536IleTrp: 0.536 ± 0.025	0.929IleTyr: 0.929 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	2.664LysAla: 2.664 ± 0.058	0.08LysCys: 0.08 ± 0.01	1.201LysAsp: 1.201 ± 0.041	1.018LysGlu: 1.018 ± 0.035	0.669LysPhe: 0.669 ± 0.028	1.806LysGly: 1.806 ± 0.053	0.537LysHis: 0.537 ± 0.024	1.186LysIle: 1.186 ± 0.038	0.916LysLys: 0.916 ± 0.042	2.393LysLeu: 2.393 ± 0.054	0.436LysMet: 0.436 ± 0.022	0.763LysAsn: 0.763 ± 0.03	1.382LysPro: 1.382 ± 0.045	0.826LysGln: 0.826 ± 0.032	1.71LysArg: 1.71 ± 0.053	1.608LysSer: 1.608 ± 0.048	1.548LysThr: 1.548 ± 0.047	1.902LysVal: 1.902 ± 0.044	0.273LysTrp: 0.273 ± 0.018	0.572LysTyr: 0.572 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	14.035LeuAla: 14.035 ± 0.142	0.52LeuCys: 0.52 ± 0.024	6.794LeuAsp: 6.794 ± 0.095	5.24LeuGlu: 5.24 ± 0.091	3.019LeuPhe: 3.019 ± 0.063	9.141LeuGly: 9.141 ± 0.129	1.761LeuHis: 1.761 ± 0.047	4.817LeuIle: 4.817 ± 0.087	2.276LeuLys: 2.276 ± 0.05	9.764LeuLeu: 9.764 ± 0.14	1.768LeuMet: 1.768 ± 0.048	2.214LeuAsn: 2.214 ± 0.053	5.308LeuPro: 5.308 ± 0.083	2.677LeuGln: 2.677 ± 0.06	6.577LeuArg: 6.577 ± 0.101	6.462LeuSer: 6.462 ± 0.081	6.153LeuThr: 6.153 ± 0.079	9.147LeuVal: 9.147 ± 0.12	1.243LeuTrp: 1.243 ± 0.039	1.72LeuTyr: 1.72 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	2.278MetAla: 2.278 ± 0.046	0.106MetCys: 0.106 ± 0.011	0.914MetAsp: 0.914 ± 0.032	0.667MetGlu: 0.667 ± 0.032	0.568MetPhe: 0.568 ± 0.025	1.386MetGly: 1.386 ± 0.042	0.373MetHis: 0.373 ± 0.02	0.991MetIle: 0.991 ± 0.036	0.537MetLys: 0.537 ± 0.025	2.036MetLeu: 2.036 ± 0.047	0.36MetMet: 0.36 ± 0.019	0.57MetAsn: 0.57 ± 0.023	1.167MetPro: 1.167 ± 0.038	0.582MetGln: 0.582 ± 0.028	1.335MetArg: 1.335 ± 0.037	1.558MetSer: 1.558 ± 0.039	1.787MetThr: 1.787 ± 0.042	1.54MetVal: 1.54 ± 0.041	0.209MetTrp: 0.209 ± 0.016	0.265MetTyr: 0.265 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.826AsnAla: 2.826 ± 0.061	0.149AsnCys: 0.149 ± 0.014	1.403AsnAsp: 1.403 ± 0.049	1.196AsnGlu: 1.196 ± 0.04	0.858AsnPhe: 0.858 ± 0.03	2.284AsnGly: 2.284 ± 0.06	0.444AsnHis: 0.444 ± 0.023	1.197AsnIle: 1.197 ± 0.037	0.534AsnLys: 0.534 ± 0.024	2.367AsnLeu: 2.367 ± 0.052	0.43AsnMet: 0.43 ± 0.024	0.725AsnAsn: 0.725 ± 0.035	1.818AsnPro: 1.818 ± 0.05	0.727AsnGln: 0.727 ± 0.032	1.512AsnArg: 1.512 ± 0.04	1.491AsnSer: 1.491 ± 0.042	1.45AsnThr: 1.45 ± 0.045	1.994AsnVal: 1.994 ± 0.048	0.416AsnTrp: 0.416 ± 0.022	0.611AsnTyr: 0.611 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	6.443ProAla: 6.443 ± 0.099	0.192ProCys: 0.192 ± 0.016	3.495ProAsp: 3.495 ± 0.073	3.319ProGlu: 3.319 ± 0.066	1.751ProPhe: 1.751 ± 0.041	4.796ProGly: 4.796 ± 0.088	1.02ProHis: 1.02 ± 0.036	2.428ProIle: 2.428 ± 0.052	1.205ProLys: 1.205 ± 0.037	4.764ProLeu: 4.764 ± 0.075	0.932ProMet: 0.932 ± 0.032	1.249ProAsn: 1.249 ± 0.037	2.129ProPro: 2.129 ± 0.071	1.5ProGln: 1.5 ± 0.041	3.03ProArg: 3.03 ± 0.066	3.207ProSer: 3.207 ± 0.061	3.363ProThr: 3.363 ± 0.07	4.678ProVal: 4.678 ± 0.079	0.853ProTrp: 0.853 ± 0.033	0.969ProTyr: 0.969 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.39GlnAla: 3.39 ± 0.064	0.139GlnCys: 0.139 ± 0.014	1.326GlnAsp: 1.326 ± 0.041	1.116GlnGlu: 1.116 ± 0.038	1.021GlnPhe: 1.021 ± 0.035	2.073GlnGly: 2.073 ± 0.05	0.652GlnHis: 0.652 ± 0.03	1.483GlnIle: 1.483 ± 0.046	0.817GlnLys: 0.817 ± 0.034	3.605GlnLeu: 3.605 ± 0.07	0.523GlnMet: 0.523 ± 0.027	0.719GlnAsn: 0.719 ± 0.028	1.616GlnPro: 1.616 ± 0.043	1.278GlnGln: 1.278 ± 0.042	2.289GlnArg: 2.289 ± 0.056	1.818GlnSer: 1.818 ± 0.047	1.341GlnThr: 1.341 ± 0.037	2.461GlnVal: 2.461 ± 0.05	0.48GlnTrp: 0.48 ± 0.022	0.665GlnTyr: 0.665 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	7.439ArgAla: 7.439 ± 0.089	0.289ArgCys: 0.289 ± 0.02	3.83ArgAsp: 3.83 ± 0.067	3.795ArgGlu: 3.795 ± 0.071	2.424ArgPhe: 2.424 ± 0.05	4.914ArgGly: 4.914 ± 0.074	1.36ArgHis: 1.36 ± 0.044	3.64ArgIle: 3.64 ± 0.066	1.632ArgLys: 1.632 ± 0.049	6.675ArgLeu: 6.675 ± 0.111	1.715ArgMet: 1.715 ± 0.042	1.631ArgAsn: 1.631 ± 0.044	3.217ArgPro: 3.217 ± 0.079	2.142ArgGln: 2.142 ± 0.058	5.209ArgArg: 5.209 ± 0.09	4.296ArgSer: 4.296 ± 0.072	3.706ArgThr: 3.706 ± 0.065	5.483ArgVal: 5.483 ± 0.09	1.04ArgTrp: 1.04 ± 0.034	1.478ArgTyr: 1.478 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	7.486SerAla: 7.486 ± 0.102	0.32SerCys: 0.32 ± 0.017	3.437SerAsp: 3.437 ± 0.063	3.015SerGlu: 3.015 ± 0.061	2.251SerPhe: 2.251 ± 0.05	6.392SerGly: 6.392 ± 0.09	1.135SerHis: 1.135 ± 0.036	3.64SerIle: 3.64 ± 0.068	1.551SerLys: 1.551 ± 0.042	6.042SerLeu: 6.042 ± 0.077	1.393SerMet: 1.393 ± 0.039	1.63SerAsn: 1.63 ± 0.048	3.31SerPro: 3.31 ± 0.066	1.792SerGln: 1.792 ± 0.049	4.387SerArg: 4.387 ± 0.072	4.315SerSer: 4.315 ± 0.085	4.497SerThr: 4.497 ± 0.084	5.562SerVal: 5.562 ± 0.092	1.022SerTrp: 1.022 ± 0.038	1.393SerTyr: 1.393 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	7.864ThrAla: 7.864 ± 0.118	0.293ThrCys: 0.293 ± 0.018	3.576ThrAsp: 3.576 ± 0.067	3.086ThrGlu: 3.086 ± 0.056	2.023ThrPhe: 2.023 ± 0.053	5.908ThrGly: 5.908 ± 0.088	1.07ThrHis: 1.07 ± 0.029	3.55ThrIle: 3.55 ± 0.07	1.336ThrLys: 1.336 ± 0.039	6.07ThrLeu: 6.07 ± 0.083	1.181ThrMet: 1.181 ± 0.034	1.534ThrAsn: 1.534 ± 0.054	3.742ThrPro: 3.742 ± 0.068	1.518ThrGln: 1.518 ± 0.038	3.56ThrArg: 3.56 ± 0.071	3.895ThrSer: 3.895 ± 0.069	4.129ThrThr: 4.129 ± 0.086	5.962ThrVal: 5.962 ± 0.094	0.865ThrTrp: 0.865 ± 0.038	1.195ThrTyr: 1.195 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	11.311ValAla: 11.311 ± 0.132	0.428ValCys: 0.428 ± 0.022	5.795ValAsp: 5.795 ± 0.085	4.561ValGlu: 4.561 ± 0.071	2.966ValPhe: 2.966 ± 0.053	7.243ValGly: 7.243 ± 0.11	1.572ValHis: 1.572 ± 0.048	5.344ValIle: 5.344 ± 0.074	1.839ValLys: 1.839 ± 0.051	8.775ValLeu: 8.775 ± 0.126	1.64ValMet: 1.64 ± 0.042	2.13ValAsn: 2.13 ± 0.05	4.282ValPro: 4.282 ± 0.074	2.203ValGln: 2.203 ± 0.056	5.248ValArg: 5.248 ± 0.079	5.711ValSer: 5.711 ± 0.084	6.178ValThr: 6.178 ± 0.107	8.364ValVal: 8.364 ± 0.129	0.998ValTrp: 0.998 ± 0.033	1.521ValTyr: 1.521 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	1.523TrpAla: 1.523 ± 0.045	0.094TrpCys: 0.094 ± 0.01	0.807TrpAsp: 0.807 ± 0.032	0.607TrpGlu: 0.607 ± 0.023	0.504TrpPhe: 0.504 ± 0.024	0.973TrpGly: 0.973 ± 0.036	0.31TrpHis: 0.31 ± 0.018	0.755TrpIle: 0.755 ± 0.028	0.385TrpLys: 0.385 ± 0.02	1.689TrpLeu: 1.689 ± 0.053	0.347TrpMet: 0.347 ± 0.019	0.463TrpAsn: 0.463 ± 0.022	0.71TrpPro: 0.71 ± 0.031	0.563TrpGln: 0.563 ± 0.03	1.058TrpArg: 1.058 ± 0.039	0.974TrpSer: 0.974 ± 0.036	0.821TrpThr: 0.821 ± 0.036	1.135TrpVal: 1.135 ± 0.038	0.316TrpTrp: 0.316 ± 0.021	0.277TrpTyr: 0.277 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.16TyrAla: 2.16 ± 0.05	0.126TyrCys: 0.126 ± 0.012	1.308TyrAsp: 1.308 ± 0.04	1.041TyrGlu: 1.041 ± 0.042	0.818TyrPhe: 0.818 ± 0.032	1.872TyrGly: 1.872 ± 0.044	0.313TyrHis: 0.313 ± 0.019	0.825TyrIle: 0.825 ± 0.033	0.439TyrLys: 0.439 ± 0.023	2.326TyrLeu: 2.326 ± 0.056	0.265TyrMet: 0.265 ± 0.018	0.544TyrAsn: 0.544 ± 0.032	1.056TyrPro: 1.056 ± 0.037	0.592TyrGln: 0.592 ± 0.026	1.534TyrArg: 1.534 ± 0.043	1.397TyrSer: 1.397 ± 0.043	1.177TyrThr: 1.177 ± 0.038	1.596TyrVal: 1.596 ± 0.047	0.346TyrTrp: 0.346 ± 0.019	0.445TyrTyr: 0.445 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2810 proteins (898122 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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