Amino acid dipepetide frequency for Terracoccus luteus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
20.349AlaAla: 20.349 ± 0.197
0.908AlaCys: 0.908 ± 0.025
8.82AlaAsp: 8.82 ± 0.104
6.847AlaGlu: 6.847 ± 0.085
3.353AlaPhe: 3.353 ± 0.052
13.284AlaGly: 13.284 ± 0.108
2.666AlaHis: 2.666 ± 0.051
3.34AlaIle: 3.34 ± 0.062
2.414AlaLys: 2.414 ± 0.06
13.786AlaLeu: 13.786 ± 0.143
2.494AlaMet: 2.494 ± 0.051
1.887AlaAsn: 1.887 ± 0.035
6.943AlaPro: 6.943 ± 0.094
3.497AlaGln: 3.497 ± 0.053
10.223AlaArg: 10.223 ± 0.11
7.136AlaSer: 7.136 ± 0.079
8.579AlaThr: 8.579 ± 0.115
13.156AlaVal: 13.156 ± 0.129
1.954AlaTrp: 1.954 ± 0.051
2.207AlaTyr: 2.207 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
0.793CysAla: 0.793 ± 0.028
0.071CysCys: 0.071 ± 0.008
0.454CysAsp: 0.454 ± 0.019
0.341CysGlu: 0.341 ± 0.019
0.188CysPhe: 0.188 ± 0.012
0.749CysGly: 0.749 ± 0.025
0.154CysHis: 0.154 ± 0.012
0.175CysIle: 0.175 ± 0.012
0.068CysLys: 0.068 ± 0.007
0.573CysLeu: 0.573 ± 0.023
0.087CysMet: 0.087 ± 0.008
0.115CysAsn: 0.115 ± 0.009
0.417CysPro: 0.417 ± 0.021
0.119CysGln: 0.119 ± 0.011
0.507CysArg: 0.507 ± 0.022
0.373CysSer: 0.373 ± 0.016
0.434CysThr: 0.434 ± 0.02
0.567CysVal: 0.567 ± 0.02
0.117CysTrp: 0.117 ± 0.017
0.116CysTyr: 0.116 ± 0.011
0.0CysXaa: 0.0 ± 0.0
Asp
9.224AspAla: 9.224 ± 0.085
0.328AspCys: 0.328 ± 0.015
5.483AspAsp: 5.483 ± 0.086
4.715AspGlu: 4.715 ± 0.068
1.45AspPhe: 1.45 ± 0.035
7.069AspGly: 7.069 ± 0.098
1.558AspHis: 1.558 ± 0.047
1.68AspIle: 1.68 ± 0.042
0.987AspLys: 0.987 ± 0.035
7.041AspLeu: 7.041 ± 0.085
0.723AspMet: 0.723 ± 0.027
0.825AspAsn: 0.825 ± 0.032
4.789AspPro: 4.789 ± 0.079
1.398AspGln: 1.398 ± 0.037
5.347AspArg: 5.347 ± 0.08
2.476AspSer: 2.476 ± 0.049
3.32AspThr: 3.32 ± 0.053
6.417AspVal: 6.417 ± 0.071
0.913AspTrp: 0.913 ± 0.037
1.085AspTyr: 1.085 ± 0.033
0.0AspXaa: 0.0 ± 0.0
Glu
6.936GluAla: 6.936 ± 0.09
0.306GluCys: 0.306 ± 0.019
2.204GluAsp: 2.204 ± 0.043
2.19GluGlu: 2.19 ± 0.045
1.307GluPhe: 1.307 ± 0.036
4.276GluGly: 4.276 ± 0.065
1.592GluHis: 1.592 ± 0.039
1.812GluIle: 1.812 ± 0.041
1.11GluLys: 1.11 ± 0.039
5.669GluLeu: 5.669 ± 0.087
0.82GluMet: 0.82 ± 0.027
0.939GluAsn: 0.939 ± 0.027
3.088GluPro: 3.088 ± 0.061
2.32GluGln: 2.32 ± 0.053
5.445GluArg: 5.445 ± 0.083
2.659GluSer: 2.659 ± 0.051
2.824GluThr: 2.824 ± 0.05
5.165GluVal: 5.165 ± 0.077
0.744GluTrp: 0.744 ± 0.028
0.879GluTyr: 0.879 ± 0.03
0.0GluXaa: 0.0 ± 0.0
Phe
3.502PheAla: 3.502 ± 0.048
0.208PheCys: 0.208 ± 0.012
2.065PheAsp: 2.065 ± 0.043
1.502PheGlu: 1.502 ± 0.041
0.833PhePhe: 0.833 ± 0.03
2.892PheGly: 2.892 ± 0.046
0.503PheHis: 0.503 ± 0.019
0.75PheIle: 0.75 ± 0.029
0.434PheLys: 0.434 ± 0.021
2.11PheLeu: 2.11 ± 0.044
0.388PheMet: 0.388 ± 0.016
0.507PheAsn: 0.507 ± 0.023
1.165PhePro: 1.165 ± 0.031
0.559PheGln: 0.559 ± 0.026
1.522PheArg: 1.522 ± 0.036
1.48PheSer: 1.48 ± 0.038
1.91PheThr: 1.91 ± 0.047
2.906PheVal: 2.906 ± 0.059
0.408PheTrp: 0.408 ± 0.019
0.583PheTyr: 0.583 ± 0.021
0.0PheXaa: 0.0 ± 0.0
Gly
11.424GlyAla: 11.424 ± 0.112
0.676GlyCys: 0.676 ± 0.025
6.024GlyAsp: 6.024 ± 0.08
4.856GlyGlu: 4.856 ± 0.068
2.769GlyPhe: 2.769 ± 0.05
8.997GlyGly: 8.997 ± 0.113
2.269GlyHis: 2.269 ± 0.046
3.611GlyIle: 3.611 ± 0.053
1.838GlyLys: 1.838 ± 0.047
9.772GlyLeu: 9.772 ± 0.087
1.793GlyMet: 1.793 ± 0.043
1.527GlyAsn: 1.527 ± 0.038
5.105GlyPro: 5.105 ± 0.071
2.674GlyGln: 2.674 ± 0.053
8.31GlyArg: 8.31 ± 0.104
6.015GlySer: 6.015 ± 0.083
6.093GlyThr: 6.093 ± 0.091
8.498GlyVal: 8.498 ± 0.096
1.784GlyTrp: 1.784 ± 0.048
2.052GlyTyr: 2.052 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
2.447HisAla: 2.447 ± 0.051
0.151HisCys: 0.151 ± 0.011
1.727HisAsp: 1.727 ± 0.039
1.331HisGlu: 1.331 ± 0.034
0.534HisPhe: 0.534 ± 0.023
2.21HisGly: 2.21 ± 0.05
0.669HisHis: 0.669 ± 0.027
0.472HisIle: 0.472 ± 0.018
0.244HisLys: 0.244 ± 0.015
2.403HisLeu: 2.403 ± 0.047
0.262HisMet: 0.262 ± 0.015
0.334HisAsn: 0.334 ± 0.016
1.769HisPro: 1.769 ± 0.043
0.493HisGln: 0.493 ± 0.022
1.924HisArg: 1.924 ± 0.041
0.848HisSer: 0.848 ± 0.028
1.099HisThr: 1.099 ± 0.032
2.251HisVal: 2.251 ± 0.044
0.344HisTrp: 0.344 ± 0.016
0.372HisTyr: 0.372 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
4.074IleAla: 4.074 ± 0.067
0.212IleCys: 0.212 ± 0.013
2.26IleAsp: 2.26 ± 0.049
1.872IleGlu: 1.872 ± 0.043
0.715IlePhe: 0.715 ± 0.027
3.191IleGly: 3.191 ± 0.062
0.518IleHis: 0.518 ± 0.022
0.855IleIle: 0.855 ± 0.03
0.565IleLys: 0.565 ± 0.025
2.075IleLeu: 2.075 ± 0.054
0.423IleMet: 0.423 ± 0.021
0.566IleAsn: 0.566 ± 0.022
1.417IlePro: 1.417 ± 0.038
0.568IleGln: 0.568 ± 0.023
1.926IleArg: 1.926 ± 0.044
1.45IleSer: 1.45 ± 0.044
1.944IleThr: 1.944 ± 0.049
2.949IleVal: 2.949 ± 0.056
0.323IleTrp: 0.323 ± 0.016
0.476IleTyr: 0.476 ± 0.023
0.0IleXaa: 0.0 ± 0.0
Lys
2.545LysAla: 2.545 ± 0.064
0.062LysCys: 0.062 ± 0.007
1.045LysAsp: 1.045 ± 0.04
0.853LysGlu: 0.853 ± 0.029
0.364LysPhe: 0.364 ± 0.019
1.625LysGly: 1.625 ± 0.047
0.348LysHis: 0.348 ± 0.017
0.641LysIle: 0.641 ± 0.025
0.639LysLys: 0.639 ± 0.032
1.358LysLeu: 1.358 ± 0.031
0.293LysMet: 0.293 ± 0.016
0.389LysAsn: 0.389 ± 0.02
1.012LysPro: 1.012 ± 0.034
0.624LysGln: 0.624 ± 0.024
1.241LysArg: 1.241 ± 0.038
0.942LysSer: 0.942 ± 0.032
1.148LysThr: 1.148 ± 0.044
1.681LysVal: 1.681 ± 0.046
0.171LysTrp: 0.171 ± 0.012
0.349LysTyr: 0.349 ± 0.017
0.0LysXaa: 0.0 ± 0.0
Leu
14.275LeuAla: 14.275 ± 0.154
0.593LeuCys: 0.593 ± 0.02
7.136LeuAsp: 7.136 ± 0.082
5.071LeuGlu: 5.071 ± 0.074
2.419LeuPhe: 2.419 ± 0.057
9.611LeuGly: 9.611 ± 0.099
2.011LeuHis: 2.011 ± 0.048
2.341LeuIle: 2.341 ± 0.053
1.533LeuLys: 1.533 ± 0.042
10.134LeuLeu: 10.134 ± 0.14
1.42LeuMet: 1.42 ± 0.037
1.386LeuAsn: 1.386 ± 0.037
5.677LeuPro: 5.677 ± 0.061
2.405LeuGln: 2.405 ± 0.045
7.818LeuArg: 7.818 ± 0.102
5.169LeuSer: 5.169 ± 0.077
6.78LeuThr: 6.78 ± 0.081
10.964LeuVal: 10.964 ± 0.12
1.249LeuTrp: 1.249 ± 0.035
1.579LeuTyr: 1.579 ± 0.038
0.0LeuXaa: 0.0 ± 0.0
Met
2.117MetAla: 2.117 ± 0.047
0.098MetCys: 0.098 ± 0.008
0.728MetAsp: 0.728 ± 0.024
0.596MetGlu: 0.596 ± 0.024
0.439MetPhe: 0.439 ± 0.02
1.303MetGly: 1.303 ± 0.037
0.334MetHis: 0.334 ± 0.017
0.516MetIle: 0.516 ± 0.024
0.344MetLys: 0.344 ± 0.016
1.582MetLeu: 1.582 ± 0.04
0.256MetMet: 0.256 ± 0.015
0.358MetAsn: 0.358 ± 0.016
1.176MetPro: 1.176 ± 0.028
0.466MetGln: 0.466 ± 0.016
1.313MetArg: 1.313 ± 0.031
1.424MetSer: 1.424 ± 0.037
1.699MetThr: 1.699 ± 0.037
1.364MetVal: 1.364 ± 0.033
0.179MetTrp: 0.179 ± 0.014
0.246MetTyr: 0.246 ± 0.012
0.0MetXaa: 0.0 ± 0.0
Asn
1.999AsnAla: 1.999 ± 0.04
0.119AsnCys: 0.119 ± 0.01
0.953AsnAsp: 0.953 ± 0.029
0.766AsnGlu: 0.766 ± 0.025
0.447AsnPhe: 0.447 ± 0.019
1.572AsnGly: 1.572 ± 0.043
0.338AsnHis: 0.338 ± 0.017
0.576AsnIle: 0.576 ± 0.024
0.308AsnLys: 0.308 ± 0.016
1.633AsnLeu: 1.633 ± 0.039
0.242AsnMet: 0.242 ± 0.014
0.397AsnAsn: 0.397 ± 0.027
1.308AsnPro: 1.308 ± 0.034
0.424AsnGln: 0.424 ± 0.019
1.156AsnArg: 1.156 ± 0.033
0.706AsnSer: 0.706 ± 0.026
0.975AsnThr: 0.975 ± 0.043
1.474AsnVal: 1.474 ± 0.037
0.223AsnTrp: 0.223 ± 0.014
0.366AsnTyr: 0.366 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
7.883ProAla: 7.883 ± 0.098
0.263ProCys: 0.263 ± 0.016
4.902ProAsp: 4.902 ± 0.063
3.556ProGlu: 3.556 ± 0.056
1.52ProPhe: 1.52 ± 0.038
6.13ProGly: 6.13 ± 0.082
1.157ProHis: 1.157 ± 0.036
1.283ProIle: 1.283 ± 0.035
0.92ProLys: 0.92 ± 0.03
4.874ProLeu: 4.874 ± 0.07
0.989ProMet: 0.989 ± 0.028
0.865ProAsn: 0.865 ± 0.028
3.038ProPro: 3.038 ± 0.066
1.483ProGln: 1.483 ± 0.037
3.927ProArg: 3.927 ± 0.063
3.587ProSer: 3.587 ± 0.067
4.429ProThr: 4.429 ± 0.074
5.789ProVal: 5.789 ± 0.074
0.953ProTrp: 0.953 ± 0.03
1.003ProTyr: 1.003 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
3.468GlnAla: 3.468 ± 0.053
0.157GlnCys: 0.157 ± 0.013
1.176GlnAsp: 1.176 ± 0.035
1.085GlnGlu: 1.085 ± 0.031
0.642GlnPhe: 0.642 ± 0.024
2.247GlnGly: 2.247 ± 0.045
0.606GlnHis: 0.606 ± 0.026
0.889GlnIle: 0.889 ± 0.027
0.571GlnLys: 0.571 ± 0.026
2.782GlnLeu: 2.782 ± 0.048
0.436GlnMet: 0.436 ± 0.018
0.456GlnAsn: 0.456 ± 0.022
1.617GlnPro: 1.617 ± 0.041
1.242GlnGln: 1.242 ± 0.039
2.536GlnArg: 2.536 ± 0.054
1.338GlnSer: 1.338 ± 0.033
1.502GlnThr: 1.502 ± 0.04
2.714GlnVal: 2.714 ± 0.046
0.478GlnTrp: 0.478 ± 0.022
0.494GlnTyr: 0.494 ± 0.024
0.0GlnXaa: 0.0 ± 0.0
Arg
9.495ArgAla: 9.495 ± 0.106
0.502ArgCys: 0.502 ± 0.023
4.944ArgAsp: 4.944 ± 0.079
4.467ArgGlu: 4.467 ± 0.08
2.281ArgPhe: 2.281 ± 0.043
6.133ArgGly: 6.133 ± 0.087
2.08ArgHis: 2.08 ± 0.047
2.525ArgIle: 2.525 ± 0.048
1.134ArgLys: 1.134 ± 0.031
8.856ArgLeu: 8.856 ± 0.095
1.627ArgMet: 1.627 ± 0.03
1.129ArgAsn: 1.129 ± 0.032
5.061ArgPro: 5.061 ± 0.084
2.165ArgGln: 2.165 ± 0.047
8.073ArgArg: 8.073 ± 0.114
4.562ArgSer: 4.562 ± 0.067
4.858ArgThr: 4.858 ± 0.063
6.903ArgVal: 6.903 ± 0.078
1.488ArgTrp: 1.488 ± 0.039
1.605ArgTyr: 1.605 ± 0.037
0.0ArgXaa: 0.0 ± 0.0
Ser
6.983SerAla: 6.983 ± 0.089
0.342SerCys: 0.342 ± 0.022
3.338SerAsp: 3.338 ± 0.058
2.329SerGlu: 2.329 ± 0.042
1.604SerPhe: 1.604 ± 0.035
6.211SerGly: 6.211 ± 0.083
1.04SerHis: 1.04 ± 0.03
1.569SerIle: 1.569 ± 0.037
0.926SerLys: 0.926 ± 0.033
5.271SerLeu: 5.271 ± 0.075
1.143SerMet: 1.143 ± 0.033
0.89SerAsn: 0.89 ± 0.03
3.321SerPro: 3.321 ± 0.053
1.36SerGln: 1.36 ± 0.035
4.135SerArg: 4.135 ± 0.068
3.505SerSer: 3.505 ± 0.074
4.033SerThr: 4.033 ± 0.088
4.847SerVal: 4.847 ± 0.072
0.897SerTrp: 0.897 ± 0.029
1.026SerTyr: 1.026 ± 0.03
0.0SerXaa: 0.0 ± 0.0
Thr
8.698ThrAla: 8.698 ± 0.14
0.441ThrCys: 0.441 ± 0.025
4.379ThrAsp: 4.379 ± 0.07
2.873ThrGlu: 2.873 ± 0.057
1.863ThrPhe: 1.863 ± 0.045
6.763ThrGly: 6.763 ± 0.085
1.274ThrHis: 1.274 ± 0.037
1.837ThrIle: 1.837 ± 0.043
1.157ThrLys: 1.157 ± 0.043
5.95ThrLeu: 5.95 ± 0.088
1.074ThrMet: 1.074 ± 0.027
1.129ThrAsn: 1.129 ± 0.042
4.493ThrPro: 4.493 ± 0.072
1.381ThrGln: 1.381 ± 0.031
4.347ThrArg: 4.347 ± 0.066
4.022ThrSer: 4.022 ± 0.071
5.242ThrThr: 5.242 ± 0.098
6.716ThrVal: 6.716 ± 0.11
1.043ThrTrp: 1.043 ± 0.034
1.337ThrTyr: 1.337 ± 0.032
0.0ThrXaa: 0.0 ± 0.0
Val
13.567ValAla: 13.567 ± 0.141
0.678ValCys: 0.678 ± 0.022
6.992ValAsp: 6.992 ± 0.08
5.44ValGlu: 5.44 ± 0.082
2.404ValPhe: 2.404 ± 0.051
8.895ValGly: 8.895 ± 0.097
2.069ValHis: 2.069 ± 0.044
2.765ValIle: 2.765 ± 0.056
1.591ValLys: 1.591 ± 0.04
9.993ValLeu: 9.993 ± 0.115
1.598ValMet: 1.598 ± 0.037
1.604ValAsn: 1.604 ± 0.042
5.378ValPro: 5.378 ± 0.07
2.207ValGln: 2.207 ± 0.043
7.25ValArg: 7.25 ± 0.081
5.15ValSer: 5.15 ± 0.071
7.245ValThr: 7.245 ± 0.133
12.359ValVal: 12.359 ± 0.15
1.227ValTrp: 1.227 ± 0.032
1.466ValTyr: 1.466 ± 0.035
0.0ValXaa: 0.0 ± 0.0
Trp
1.709TrpAla: 1.709 ± 0.044
0.166TrpCys: 0.166 ± 0.012
0.834TrpAsp: 0.834 ± 0.033
0.546TrpGlu: 0.546 ± 0.021
0.538TrpPhe: 0.538 ± 0.023
1.181TrpGly: 1.181 ± 0.034
0.369TrpHis: 0.369 ± 0.021
0.366TrpIle: 0.366 ± 0.017
0.269TrpLys: 0.269 ± 0.016
1.798TrpLeu: 1.798 ± 0.045
0.284TrpMet: 0.284 ± 0.017
0.324TrpAsn: 0.324 ± 0.016
0.825TrpPro: 0.825 ± 0.032
0.569TrpGln: 0.569 ± 0.026
1.349TrpArg: 1.349 ± 0.041
1.06TrpSer: 1.06 ± 0.031
0.877TrpThr: 0.877 ± 0.028
1.426TrpVal: 1.426 ± 0.035
0.378TrpTrp: 0.378 ± 0.02
0.292TrpTyr: 0.292 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.354TyrAla: 2.354 ± 0.044
0.14TyrCys: 0.14 ± 0.01
1.364TyrAsp: 1.364 ± 0.032
1.05TyrGlu: 1.05 ± 0.033
0.557TyrPhe: 0.557 ± 0.021
1.746TyrGly: 1.746 ± 0.039
0.327TyrHis: 0.327 ± 0.017
0.378TyrIle: 0.378 ± 0.018
0.28TyrLys: 0.28 ± 0.014
1.912TyrLeu: 1.912 ± 0.043
0.185TyrMet: 0.185 ± 0.01
0.355TyrAsn: 0.355 ± 0.018
0.951TyrPro: 0.951 ± 0.031
0.482TyrGln: 0.482 ± 0.022
1.537TyrArg: 1.537 ± 0.034
0.869TyrSer: 0.869 ± 0.03
1.026TyrThr: 1.026 ± 0.035
1.729TyrVal: 1.729 ± 0.039
0.29TyrTrp: 0.29 ± 0.015
0.404TyrTyr: 0.404 ± 0.02
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3555 proteins (1213893 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski