Amino acid dipepetide frequency for Panthera leo polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.66AlaAla: 4.66 ± 1.749
4.66AlaCys: 4.66 ± 1.431
1.997AlaAsp: 1.997 ± 0.601
5.326AlaGlu: 5.326 ± 1.142
3.329AlaPhe: 3.329 ± 1.214
4.66AlaGly: 4.66 ± 1.098
0.0AlaHis: 0.0 ± 0.0
5.659AlaIle: 5.659 ± 1.306
1.664AlaLys: 1.664 ± 1.002
7.324AlaLeu: 7.324 ± 2.895
0.666AlaMet: 0.666 ± 0.465
1.664AlaAsn: 1.664 ± 0.469
2.663AlaPro: 2.663 ± 1.048
6.658AlaGln: 6.658 ± 0.847
1.997AlaArg: 1.997 ± 0.832
2.996AlaSer: 2.996 ± 0.636
1.997AlaThr: 1.997 ± 0.96
2.996AlaVal: 2.996 ± 1.209
1.664AlaTrp: 1.664 ± 0.529
0.333AlaTyr: 0.333 ± 0.361
0.0AlaXaa: 0.0 ± 0.0
Cys
0.333CysAla: 0.333 ± 0.358
0.666CysCys: 0.666 ± 0.567
2.33CysAsp: 2.33 ± 0.77
1.997CysGlu: 1.997 ± 0.842
1.664CysPhe: 1.664 ± 0.774
1.664CysGly: 1.664 ± 0.531
0.0CysHis: 0.0 ± 0.0
2.33CysIle: 2.33 ± 0.67
4.328CysLys: 4.328 ± 0.814
4.993CysLeu: 4.993 ± 1.329
1.332CysMet: 1.332 ± 0.6
0.999CysAsn: 0.999 ± 0.356
0.666CysPro: 0.666 ± 0.525
0.666CysGln: 0.666 ± 0.281
0.666CysArg: 0.666 ± 0.281
1.332CysSer: 1.332 ± 0.496
0.666CysThr: 0.666 ± 0.281
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.999CysTyr: 0.999 ± 0.843
0.0CysXaa: 0.0 ± 0.0
Asp
1.332AspAla: 1.332 ± 0.343
1.332AspCys: 1.332 ± 0.562
0.999AspAsp: 0.999 ± 0.354
3.329AspGlu: 3.329 ± 1.404
1.997AspPhe: 1.997 ± 0.842
3.995AspGly: 3.995 ± 0.477
3.329AspHis: 3.329 ± 0.826
3.662AspIle: 3.662 ± 0.928
2.996AspLys: 2.996 ± 0.743
5.992AspLeu: 5.992 ± 0.909
2.33AspMet: 2.33 ± 0.713
4.328AspAsn: 4.328 ± 1.056
1.664AspPro: 1.664 ± 1.068
3.662AspGln: 3.662 ± 0.692
1.332AspArg: 1.332 ± 0.931
2.663AspSer: 2.663 ± 0.681
2.33AspThr: 2.33 ± 0.539
0.666AspVal: 0.666 ± 0.281
1.664AspTrp: 1.664 ± 0.633
1.664AspTyr: 1.664 ± 0.367
0.0AspXaa: 0.0 ± 0.0
Glu
4.993GluAla: 4.993 ± 1.951
1.332GluCys: 1.332 ± 0.496
5.326GluAsp: 5.326 ± 0.973
9.321GluGlu: 9.321 ± 1.62
2.663GluPhe: 2.663 ± 0.703
3.329GluGly: 3.329 ± 0.857
1.332GluHis: 1.332 ± 0.411
1.332GluIle: 1.332 ± 0.437
5.659GluLys: 5.659 ± 1.769
7.989GluLeu: 7.989 ± 1.441
0.0GluMet: 0.0 ± 0.0
3.329GluAsn: 3.329 ± 0.735
1.664GluPro: 1.664 ± 0.715
3.662GluGln: 3.662 ± 1.067
1.332GluArg: 1.332 ± 0.411
9.321GluSer: 9.321 ± 2.445
3.329GluThr: 3.329 ± 1.037
4.993GluVal: 4.993 ± 1.899
0.0GluTrp: 0.0 ± 0.0
3.995GluTyr: 3.995 ± 1.041
0.0GluXaa: 0.0 ± 0.0
Phe
2.663PheAla: 2.663 ± 0.703
3.662PheCys: 3.662 ± 1.127
3.329PheAsp: 3.329 ± 0.935
3.662PheGlu: 3.662 ± 0.903
0.333PhePhe: 0.333 ± 0.334
1.997PheGly: 1.997 ± 0.715
0.333PheHis: 0.333 ± 0.361
2.996PheIle: 2.996 ± 0.831
2.33PheLys: 2.33 ± 1.694
7.656PheLeu: 7.656 ± 1.613
0.666PheMet: 0.666 ± 0.663
2.663PheAsn: 2.663 ± 0.617
4.993PhePro: 4.993 ± 0.864
0.666PheGln: 0.666 ± 0.465
0.666PheArg: 0.666 ± 0.721
1.332PheSer: 1.332 ± 0.66
2.996PheThr: 2.996 ± 0.849
1.997PheVal: 1.997 ± 0.463
0.0PheTrp: 0.0 ± 0.0
0.999PheTyr: 0.999 ± 0.509
0.0PheXaa: 0.0 ± 0.0
Gly
5.326GlyAla: 5.326 ± 1.506
0.333GlyCys: 0.333 ± 0.331
2.663GlyAsp: 2.663 ± 0.848
2.33GlyGlu: 2.33 ± 0.71
2.33GlyPhe: 2.33 ± 0.508
4.993GlyGly: 4.993 ± 0.688
0.0GlyHis: 0.0 ± 0.0
4.993GlyIle: 4.993 ± 0.77
2.33GlyLys: 2.33 ± 0.997
6.658GlyLeu: 6.658 ± 1.765
0.333GlyMet: 0.333 ± 0.334
6.325GlyAsn: 6.325 ± 2.333
2.33GlyPro: 2.33 ± 0.658
2.663GlyGln: 2.663 ± 0.554
1.664GlyArg: 1.664 ± 0.894
2.663GlySer: 2.663 ± 0.414
0.666GlyThr: 0.666 ± 0.281
4.66GlyVal: 4.66 ± 0.995
0.0GlyTrp: 0.0 ± 0.0
0.333GlyTyr: 0.333 ± 0.361
0.0GlyXaa: 0.0 ± 0.0
His
0.666HisAla: 0.666 ± 0.465
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.666HisHis: 0.666 ± 0.281
2.663HisIle: 2.663 ± 0.802
1.332HisLys: 1.332 ± 0.562
0.0HisLeu: 0.0 ± 0.0
0.999HisMet: 0.999 ± 0.356
0.333HisAsn: 0.333 ± 0.361
1.997HisPro: 1.997 ± 0.724
0.666HisGln: 0.666 ± 0.281
0.999HisArg: 0.999 ± 0.398
1.332HisSer: 1.332 ± 0.587
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.997HisTyr: 1.997 ± 0.528
0.0HisXaa: 0.0 ± 0.0
Ile
2.996IleAla: 2.996 ± 0.53
1.664IleCys: 1.664 ± 0.531
3.329IleAsp: 3.329 ± 0.712
1.997IleGlu: 1.997 ± 1.146
0.999IlePhe: 0.999 ± 0.354
1.997IleGly: 1.997 ± 0.582
0.666IleHis: 0.666 ± 0.465
1.664IleIle: 1.664 ± 0.564
2.996IleLys: 2.996 ± 0.883
7.989IleLeu: 7.989 ± 1.457
1.664IleMet: 1.664 ± 0.466
3.662IleAsn: 3.662 ± 0.832
5.326IlePro: 5.326 ± 1.224
0.999IleGln: 0.999 ± 0.514
0.333IleArg: 0.333 ± 0.361
4.66IleSer: 4.66 ± 0.871
2.996IleThr: 2.996 ± 0.74
1.997IleVal: 1.997 ± 0.842
0.0IleTrp: 0.0 ± 0.0
3.329IleTyr: 3.329 ± 0.564
0.0IleXaa: 0.0 ± 0.0
Lys
5.992LysAla: 5.992 ± 1.146
1.997LysCys: 1.997 ± 0.707
4.993LysAsp: 4.993 ± 1.236
5.659LysGlu: 5.659 ± 1.071
1.332LysPhe: 1.332 ± 0.562
6.325LysGly: 6.325 ± 1.63
1.332LysHis: 1.332 ± 0.562
5.326LysIle: 5.326 ± 0.957
6.991LysLys: 6.991 ± 1.694
4.993LysLeu: 4.993 ± 0.856
2.33LysMet: 2.33 ± 0.771
3.662LysAsn: 3.662 ± 1.123
1.332LysPro: 1.332 ± 0.477
1.332LysGln: 1.332 ± 0.477
5.659LysArg: 5.659 ± 0.842
1.997LysSer: 1.997 ± 0.785
4.993LysThr: 4.993 ± 0.915
2.663LysVal: 2.663 ± 0.753
0.0LysTrp: 0.0 ± 0.0
0.666LysTyr: 0.666 ± 0.542
0.0LysXaa: 0.0 ± 0.0
Leu
6.991LeuAla: 6.991 ± 3.324
3.329LeuCys: 3.329 ± 0.581
6.991LeuAsp: 6.991 ± 0.937
8.655LeuGlu: 8.655 ± 1.657
5.992LeuPhe: 5.992 ± 1.376
3.329LeuGly: 3.329 ± 1.103
1.997LeuHis: 1.997 ± 0.724
5.992LeuIle: 5.992 ± 0.571
7.989LeuLys: 7.989 ± 1.803
14.314LeuLeu: 14.314 ± 2.629
4.993LeuMet: 4.993 ± 1.547
7.989LeuAsn: 7.989 ± 1.756
8.655LeuPro: 8.655 ± 1.745
4.328LeuGln: 4.328 ± 1.056
3.995LeuArg: 3.995 ± 1.087
5.659LeuSer: 5.659 ± 1.694
5.659LeuThr: 5.659 ± 0.621
2.663LeuVal: 2.663 ± 0.837
0.666LeuTrp: 0.666 ± 0.502
7.656LeuTyr: 7.656 ± 1.273
0.0LeuXaa: 0.0 ± 0.0
Met
1.997MetAla: 1.997 ± 0.601
1.332MetCys: 1.332 ± 0.626
1.997MetAsp: 1.997 ± 0.724
4.66MetGlu: 4.66 ± 0.771
1.664MetPhe: 1.664 ± 0.353
1.997MetGly: 1.997 ± 0.845
0.666MetHis: 0.666 ± 0.465
1.664MetIle: 1.664 ± 0.531
0.999MetLys: 0.999 ± 0.354
1.664MetLeu: 1.664 ± 0.776
0.0MetMet: 0.0 ± 0.0
0.666MetAsn: 0.666 ± 0.281
0.666MetPro: 0.666 ± 0.281
0.666MetGln: 0.666 ± 0.721
2.33MetArg: 2.33 ± 0.9
0.0MetSer: 0.0 ± 0.0
2.996MetThr: 2.996 ± 0.883
0.333MetVal: 0.333 ± 0.361
0.333MetTrp: 0.333 ± 0.361
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.329AsnAla: 3.329 ± 0.72
0.999AsnCys: 0.999 ± 0.354
0.0AsnAsp: 0.0 ± 0.0
1.664AsnGlu: 1.664 ± 1.002
5.326AsnPhe: 5.326 ± 0.494
1.332AsnGly: 1.332 ± 0.437
0.0AsnHis: 0.0 ± 0.0
3.329AsnIle: 3.329 ± 0.959
4.328AsnLys: 4.328 ± 1.384
6.658AsnLeu: 6.658 ± 0.81
1.332AsnMet: 1.332 ± 0.336
1.332AsnAsn: 1.332 ± 0.349
6.991AsnPro: 6.991 ± 1.87
2.996AsnGln: 2.996 ± 0.471
0.999AsnArg: 0.999 ± 0.509
2.663AsnSer: 2.663 ± 0.641
2.33AsnThr: 2.33 ± 0.997
2.33AsnVal: 2.33 ± 0.404
0.666AsnTrp: 0.666 ± 0.465
1.332AsnTyr: 1.332 ± 0.727
0.0AsnXaa: 0.0 ± 0.0
Pro
2.996ProAla: 2.996 ± 0.94
0.333ProCys: 0.333 ± 0.361
6.325ProAsp: 6.325 ± 0.968
2.663ProGlu: 2.663 ± 0.998
0.999ProPhe: 0.999 ± 0.384
3.995ProGly: 3.995 ± 0.87
0.333ProHis: 0.333 ± 0.361
1.664ProIle: 1.664 ± 0.881
3.662ProLys: 3.662 ± 0.777
7.989ProLeu: 7.989 ± 1.518
2.996ProMet: 2.996 ± 0.897
0.999ProAsn: 0.999 ± 0.398
6.325ProPro: 6.325 ± 1.324
4.328ProGln: 4.328 ± 0.856
1.332ProArg: 1.332 ± 1.013
5.326ProSer: 5.326 ± 1.167
1.332ProThr: 1.332 ± 0.411
2.33ProVal: 2.33 ± 0.658
0.0ProTrp: 0.0 ± 0.0
2.663ProTyr: 2.663 ± 0.554
0.0ProXaa: 0.0 ± 0.0
Gln
4.328GlnAla: 4.328 ± 0.514
0.666GlnCys: 0.666 ± 0.281
1.332GlnAsp: 1.332 ± 0.66
6.991GlnGlu: 6.991 ± 1.848
1.997GlnPhe: 1.997 ± 0.53
1.332GlnGly: 1.332 ± 0.349
0.0GlnHis: 0.0 ± 0.0
1.664GlnIle: 1.664 ± 0.526
1.664GlnLys: 1.664 ± 0.604
5.659GlnLeu: 5.659 ± 1.847
0.666GlnMet: 0.666 ± 0.721
3.329GlnAsn: 3.329 ± 0.986
1.332GlnPro: 1.332 ± 0.66
2.663GlnGln: 2.663 ± 1.123
6.658GlnArg: 6.658 ± 2.454
1.332GlnSer: 1.332 ± 0.437
1.332GlnThr: 1.332 ± 0.931
1.997GlnVal: 1.997 ± 0.927
0.666GlnTrp: 0.666 ± 0.281
1.997GlnTyr: 1.997 ± 0.542
0.0GlnXaa: 0.0 ± 0.0
Arg
3.329ArgAla: 3.329 ± 1.094
0.666ArgCys: 0.666 ± 0.281
2.33ArgAsp: 2.33 ± 0.77
3.662ArgGlu: 3.662 ± 0.561
4.328ArgPhe: 4.328 ± 0.865
2.33ArgGly: 2.33 ± 1.033
0.999ArgHis: 0.999 ± 0.398
0.666ArgIle: 0.666 ± 0.281
6.658ArgLys: 6.658 ± 0.902
3.995ArgLeu: 3.995 ± 0.609
0.999ArgMet: 0.999 ± 0.569
0.999ArgAsn: 0.999 ± 0.356
1.664ArgPro: 1.664 ± 0.704
1.997ArgGln: 1.997 ± 1.396
6.658ArgArg: 6.658 ± 1.243
2.33ArgSer: 2.33 ± 0.77
0.999ArgThr: 0.999 ± 0.678
3.995ArgVal: 3.995 ± 0.708
0.666ArgTrp: 0.666 ± 0.465
3.662ArgTyr: 3.662 ± 0.928
0.0ArgXaa: 0.0 ± 0.0
Ser
3.329SerAla: 3.329 ± 1.291
0.666SerCys: 0.666 ± 0.281
2.33SerAsp: 2.33 ± 0.737
1.997SerGlu: 1.997 ± 0.514
3.662SerPhe: 3.662 ± 0.793
0.666SerGly: 0.666 ± 0.426
0.999SerHis: 0.999 ± 0.509
0.666SerIle: 0.666 ± 0.281
5.992SerLys: 5.992 ± 0.895
7.989SerLeu: 7.989 ± 2.327
1.664SerMet: 1.664 ± 0.531
2.663SerAsn: 2.663 ± 0.74
1.997SerPro: 1.997 ± 1.043
3.995SerGln: 3.995 ± 0.993
6.325SerArg: 6.325 ± 1.732
2.663SerSer: 2.663 ± 0.598
2.33SerThr: 2.33 ± 0.771
4.66SerVal: 4.66 ± 1.174
1.664SerTrp: 1.664 ± 0.48
0.666SerTyr: 0.666 ± 0.426
0.0SerXaa: 0.0 ± 0.0
Thr
2.996ThrAla: 2.996 ± 1.25
1.664ThrCys: 1.664 ± 0.531
1.997ThrAsp: 1.997 ± 0.724
3.995ThrGlu: 3.995 ± 0.623
0.666ThrPhe: 0.666 ± 0.281
1.997ThrGly: 1.997 ± 0.713
0.666ThrHis: 0.666 ± 0.281
1.997ThrIle: 1.997 ± 0.601
0.999ThrLys: 0.999 ± 1.082
5.659ThrLeu: 5.659 ± 0.68
0.999ThrMet: 0.999 ± 0.509
2.33ThrAsn: 2.33 ± 0.71
4.993ThrPro: 4.993 ± 0.909
3.995ThrGln: 3.995 ± 0.569
3.329ThrArg: 3.329 ± 0.72
1.664ThrSer: 1.664 ± 0.529
4.328ThrThr: 4.328 ± 0.62
1.332ThrVal: 1.332 ± 0.66
0.333ThrTrp: 0.333 ± 0.331
0.333ThrTyr: 0.333 ± 0.377
0.0ThrXaa: 0.0 ± 0.0
Val
1.997ValAla: 1.997 ± 0.463
0.999ValCys: 0.999 ± 0.384
2.996ValAsp: 2.996 ± 0.731
4.328ValGlu: 4.328 ± 0.707
2.33ValPhe: 2.33 ± 0.61
1.664ValGly: 1.664 ± 0.605
0.333ValHis: 0.333 ± 0.361
1.332ValIle: 1.332 ± 0.562
2.996ValLys: 2.996 ± 0.546
4.993ValLeu: 4.993 ± 1.117
0.0ValMet: 0.0 ± 0.0
2.33ValAsn: 2.33 ± 0.771
2.33ValPro: 2.33 ± 0.658
0.0ValGln: 0.0 ± 0.0
1.664ValArg: 1.664 ± 0.719
4.993ValSer: 4.993 ± 1.24
2.663ValThr: 2.663 ± 1.294
1.997ValVal: 1.997 ± 0.925
1.997ValTrp: 1.997 ± 0.862
1.997ValTyr: 1.997 ± 0.514
0.0ValXaa: 0.0 ± 0.0
Trp
1.664TrpAla: 1.664 ± 1.022
0.333TrpCys: 0.333 ± 0.361
0.0TrpAsp: 0.0 ± 0.0
1.664TrpGlu: 1.664 ± 0.367
0.999TrpPhe: 0.999 ± 0.384
0.999TrpGly: 0.999 ± 0.592
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.663TrpLys: 2.663 ± 0.7
0.999TrpLeu: 0.999 ± 0.398
0.999TrpMet: 0.999 ± 0.704
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.333TrpGln: 0.333 ± 0.358
0.666TrpArg: 0.666 ± 0.281
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.666TrpTrp: 0.666 ± 0.281
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.999TyrAla: 0.999 ± 0.736
0.999TyrCys: 0.999 ± 0.384
0.0TyrAsp: 0.0 ± 0.0
0.999TyrGlu: 0.999 ± 0.356
3.329TyrPhe: 3.329 ± 0.735
4.993TyrGly: 4.993 ± 1.227
0.0TyrHis: 0.0 ± 0.0
1.664TyrIle: 1.664 ± 0.996
0.999TyrLys: 0.999 ± 0.356
4.328TyrLeu: 4.328 ± 0.789
1.332TyrMet: 1.332 ± 0.551
0.333TyrAsn: 0.333 ± 0.334
0.999TyrPro: 0.999 ± 1.082
1.332TyrGln: 1.332 ± 0.411
4.328TyrArg: 4.328 ± 0.812
1.997TyrSer: 1.997 ± 0.53
2.33TyrThr: 2.33 ± 0.44
2.33TyrVal: 2.33 ± 0.864
1.332TyrTrp: 1.332 ± 0.562
1.997TyrTyr: 1.997 ± 0.45
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (3005 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski