Amino acid dipepetide frequency for Avian paramyxovirus goose/Shimane/67/2000

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.377AlaAla: 7.377 ± 1.112
0.651AlaCys: 0.651 ± 0.346
2.17AlaAsp: 2.17 ± 0.632
6.075AlaGlu: 6.075 ± 1.048
2.604AlaPhe: 2.604 ± 0.698
4.556AlaGly: 4.556 ± 1.11
1.302AlaHis: 1.302 ± 0.472
4.773AlaIle: 4.773 ± 1.075
4.556AlaLys: 4.556 ± 0.72
6.075AlaLeu: 6.075 ± 1.021
2.604AlaMet: 2.604 ± 0.801
4.556AlaAsn: 4.556 ± 1.0
1.953AlaPro: 1.953 ± 1.164
2.604AlaGln: 2.604 ± 0.695
3.471AlaArg: 3.471 ± 0.749
4.773AlaSer: 4.773 ± 1.616
4.556AlaThr: 4.556 ± 1.211
4.339AlaVal: 4.339 ± 1.422
0.217AlaTrp: 0.217 ± 0.272
1.085AlaTyr: 1.085 ± 0.46
0.0AlaXaa: 0.0 ± 0.0
Cys
1.519CysAla: 1.519 ± 0.5
0.651CysCys: 0.651 ± 0.286
1.085CysAsp: 1.085 ± 0.459
0.651CysGlu: 0.651 ± 0.391
0.651CysPhe: 0.651 ± 0.346
0.434CysGly: 0.434 ± 0.356
0.434CysHis: 0.434 ± 0.261
1.302CysIle: 1.302 ± 0.574
0.868CysLys: 0.868 ± 0.717
2.387CysLeu: 2.387 ± 0.498
0.651CysMet: 0.651 ± 0.254
1.302CysAsn: 1.302 ± 0.555
0.651CysPro: 0.651 ± 0.6
1.302CysGln: 1.302 ± 0.339
1.519CysArg: 1.519 ± 0.592
1.519CysSer: 1.519 ± 0.693
0.434CysThr: 0.434 ± 0.303
1.302CysVal: 1.302 ± 0.469
0.0CysTrp: 0.0 ± 0.0
0.651CysTyr: 0.651 ± 0.346
0.0CysXaa: 0.0 ± 0.0
Asp
3.688AspAla: 3.688 ± 1.056
1.519AspCys: 1.519 ± 0.652
4.122AspAsp: 4.122 ± 0.667
3.255AspGlu: 3.255 ± 1.16
2.604AspPhe: 2.604 ± 0.47
3.038AspGly: 3.038 ± 0.767
0.434AspHis: 0.434 ± 0.261
3.905AspIle: 3.905 ± 0.551
3.038AspLys: 3.038 ± 0.461
5.207AspLeu: 5.207 ± 0.728
1.736AspMet: 1.736 ± 0.451
3.471AspAsn: 3.471 ± 0.3
3.905AspPro: 3.905 ± 0.781
2.604AspGln: 2.604 ± 0.793
1.302AspArg: 1.302 ± 0.424
3.905AspSer: 3.905 ± 0.991
2.604AspThr: 2.604 ± 0.494
1.302AspVal: 1.302 ± 0.383
0.217AspTrp: 0.217 ± 0.256
1.085AspTyr: 1.085 ± 0.37
0.0AspXaa: 0.0 ± 0.0
Glu
3.255GluAla: 3.255 ± 0.451
0.868GluCys: 0.868 ± 0.309
2.387GluAsp: 2.387 ± 0.589
2.387GluGlu: 2.387 ± 0.441
1.953GluPhe: 1.953 ± 0.948
2.821GluGly: 2.821 ± 0.484
0.434GluHis: 0.434 ± 0.225
5.641GluIle: 5.641 ± 0.459
2.604GluLys: 2.604 ± 0.476
5.424GluLeu: 5.424 ± 1.303
0.868GluMet: 0.868 ± 0.277
2.17GluAsn: 2.17 ± 0.485
0.868GluPro: 0.868 ± 0.414
1.519GluGln: 1.519 ± 0.377
3.255GluArg: 3.255 ± 0.854
5.207GluSer: 5.207 ± 0.714
2.604GluThr: 2.604 ± 1.117
3.688GluVal: 3.688 ± 1.239
0.651GluTrp: 0.651 ± 0.391
1.953GluTyr: 1.953 ± 0.376
0.0GluXaa: 0.0 ± 0.0
Phe
2.17PheAla: 2.17 ± 0.578
0.651PheCys: 0.651 ± 0.254
2.387PheAsp: 2.387 ± 0.827
1.736PheGlu: 1.736 ± 0.822
2.387PhePhe: 2.387 ± 0.844
2.17PheGly: 2.17 ± 0.806
0.868PheHis: 0.868 ± 0.351
3.038PheIle: 3.038 ± 0.75
1.953PheLys: 1.953 ± 0.578
3.255PheLeu: 3.255 ± 0.825
1.085PheMet: 1.085 ± 0.444
1.519PheAsn: 1.519 ± 0.455
1.736PhePro: 1.736 ± 0.505
1.085PheGln: 1.085 ± 0.459
1.085PheArg: 1.085 ± 0.47
2.821PheSer: 2.821 ± 0.461
1.736PheThr: 1.736 ± 0.232
1.953PheVal: 1.953 ± 0.581
0.0PheTrp: 0.0 ± 0.0
0.651PheTyr: 0.651 ± 0.265
0.0PheXaa: 0.0 ± 0.0
Gly
3.688GlyAla: 3.688 ± 1.205
1.519GlyCys: 1.519 ± 0.856
4.773GlyAsp: 4.773 ± 0.985
2.821GlyGlu: 2.821 ± 0.718
1.085GlyPhe: 1.085 ± 0.339
4.556GlyGly: 4.556 ± 0.894
1.302GlyHis: 1.302 ± 0.576
4.773GlyIle: 4.773 ± 0.572
3.255GlyLys: 3.255 ± 0.845
5.207GlyLeu: 5.207 ± 0.884
1.736GlyMet: 1.736 ± 0.828
4.773GlyAsn: 4.773 ± 1.335
1.736GlyPro: 1.736 ± 1.003
1.519GlyGln: 1.519 ± 0.367
3.255GlyArg: 3.255 ± 0.452
5.641GlySer: 5.641 ± 0.935
5.207GlyThr: 5.207 ± 1.245
4.99GlyVal: 4.99 ± 0.771
0.217GlyTrp: 0.217 ± 0.256
1.085GlyTyr: 1.085 ± 0.317
0.0GlyXaa: 0.0 ± 0.0
His
0.651HisAla: 0.651 ± 0.286
0.217HisCys: 0.217 ± 0.13
0.217HisAsp: 0.217 ± 0.256
0.434HisGlu: 0.434 ± 0.304
0.651HisPhe: 0.651 ± 0.391
1.085HisGly: 1.085 ± 0.282
0.217HisHis: 0.217 ± 0.13
0.868HisIle: 0.868 ± 0.374
0.651HisLys: 0.651 ± 0.391
2.604HisLeu: 2.604 ± 1.11
0.0HisMet: 0.0 ± 0.0
1.085HisAsn: 1.085 ± 0.491
2.387HisPro: 2.387 ± 0.696
0.868HisGln: 0.868 ± 0.33
1.953HisArg: 1.953 ± 0.743
1.302HisSer: 1.302 ± 0.296
0.434HisThr: 0.434 ± 0.261
1.519HisVal: 1.519 ± 0.25
0.434HisTrp: 0.434 ± 0.225
0.434HisTyr: 0.434 ± 0.261
0.0HisXaa: 0.0 ± 0.0
Ile
6.509IleAla: 6.509 ± 1.606
0.868IleCys: 0.868 ± 0.299
6.292IleAsp: 6.292 ± 0.829
3.688IleGlu: 3.688 ± 1.2
3.038IlePhe: 3.038 ± 0.846
5.424IleGly: 5.424 ± 0.887
1.519IleHis: 1.519 ± 0.473
6.075IleIle: 6.075 ± 1.605
4.122IleLys: 4.122 ± 0.608
7.594IleLeu: 7.594 ± 1.135
2.604IleMet: 2.604 ± 0.814
3.688IleAsn: 3.688 ± 0.789
3.471IlePro: 3.471 ± 0.547
3.038IleGln: 3.038 ± 1.356
3.255IleArg: 3.255 ± 0.705
8.462IleSer: 8.462 ± 0.843
4.99IleThr: 4.99 ± 1.204
3.688IleVal: 3.688 ± 0.687
0.651IleTrp: 0.651 ± 0.301
2.604IleTyr: 2.604 ± 0.682
0.0IleXaa: 0.0 ± 0.0
Lys
1.953LysAla: 1.953 ± 0.59
0.651LysCys: 0.651 ± 0.333
2.387LysAsp: 2.387 ± 1.205
3.905LysGlu: 3.905 ± 0.721
0.651LysPhe: 0.651 ± 0.399
3.471LysGly: 3.471 ± 1.117
0.868LysHis: 0.868 ± 0.33
6.943LysIle: 6.943 ± 1.65
4.556LysLys: 4.556 ± 0.932
6.292LysLeu: 6.292 ± 1.128
1.085LysMet: 1.085 ± 0.346
1.736LysAsn: 1.736 ± 0.857
1.302LysPro: 1.302 ± 0.608
2.17LysGln: 2.17 ± 0.732
1.953LysArg: 1.953 ± 0.585
4.773LysSer: 4.773 ± 1.452
2.604LysThr: 2.604 ± 0.748
2.821LysVal: 2.821 ± 1.381
0.0LysTrp: 0.0 ± 0.0
1.736LysTyr: 1.736 ± 0.671
0.0LysXaa: 0.0 ± 0.0
Leu
8.896LeuAla: 8.896 ± 1.879
2.604LeuCys: 2.604 ± 0.852
5.424LeuAsp: 5.424 ± 0.22
5.424LeuGlu: 5.424 ± 0.488
2.387LeuPhe: 2.387 ± 0.734
5.207LeuGly: 5.207 ± 0.918
1.519LeuHis: 1.519 ± 0.679
7.811LeuIle: 7.811 ± 1.586
4.556LeuLys: 4.556 ± 0.31
9.98LeuLeu: 9.98 ± 1.586
2.821LeuMet: 2.821 ± 0.586
5.641LeuAsn: 5.641 ± 1.128
2.604LeuPro: 2.604 ± 0.741
3.038LeuGln: 3.038 ± 0.869
4.122LeuArg: 4.122 ± 0.941
11.499LeuSer: 11.499 ± 1.873
8.679LeuThr: 8.679 ± 1.336
3.471LeuVal: 3.471 ± 0.788
1.519LeuTrp: 1.519 ± 0.518
3.688LeuTyr: 3.688 ± 1.135
0.0LeuXaa: 0.0 ± 0.0
Met
2.604MetAla: 2.604 ± 0.539
0.651MetCys: 0.651 ± 0.391
0.868MetAsp: 0.868 ± 0.466
1.085MetGlu: 1.085 ± 0.587
0.868MetPhe: 0.868 ± 0.345
1.085MetGly: 1.085 ± 0.238
0.868MetHis: 0.868 ± 0.348
1.953MetIle: 1.953 ± 0.548
0.651MetLys: 0.651 ± 0.286
3.471MetLeu: 3.471 ± 1.386
0.651MetMet: 0.651 ± 0.568
1.302MetAsn: 1.302 ± 0.418
0.651MetPro: 0.651 ± 0.254
1.519MetGln: 1.519 ± 0.514
1.736MetArg: 1.736 ± 0.859
2.387MetSer: 2.387 ± 0.509
1.953MetThr: 1.953 ± 0.697
1.736MetVal: 1.736 ± 0.444
0.434MetTrp: 0.434 ± 0.304
1.302MetTyr: 1.302 ± 0.241
0.0MetXaa: 0.0 ± 0.0
Asn
3.905AsnAla: 3.905 ± 1.279
0.868AsnCys: 0.868 ± 0.345
4.339AsnAsp: 4.339 ± 0.888
1.953AsnGlu: 1.953 ± 0.72
0.651AsnPhe: 0.651 ± 0.327
4.122AsnGly: 4.122 ± 0.775
1.519AsnHis: 1.519 ± 0.691
3.255AsnIle: 3.255 ± 0.704
3.038AsnLys: 3.038 ± 0.699
5.641AsnLeu: 5.641 ± 1.85
1.302AsnMet: 1.302 ± 0.318
1.736AsnAsn: 1.736 ± 0.811
2.821AsnPro: 2.821 ± 0.485
1.736AsnGln: 1.736 ± 0.789
2.387AsnArg: 2.387 ± 0.343
3.471AsnSer: 3.471 ± 0.626
3.038AsnThr: 3.038 ± 0.614
1.953AsnVal: 1.953 ± 0.829
0.651AsnTrp: 0.651 ± 0.391
1.519AsnTyr: 1.519 ± 0.392
0.0AsnXaa: 0.0 ± 0.0
Pro
3.905ProAla: 3.905 ± 1.017
0.868ProCys: 0.868 ± 0.188
1.519ProAsp: 1.519 ± 0.235
2.387ProGlu: 2.387 ± 0.557
2.387ProPhe: 2.387 ± 0.583
3.255ProGly: 3.255 ± 0.751
0.868ProHis: 0.868 ± 0.37
3.255ProIle: 3.255 ± 0.82
1.302ProLys: 1.302 ± 0.405
3.905ProLeu: 3.905 ± 0.635
0.868ProMet: 0.868 ± 0.79
1.085ProAsn: 1.085 ± 0.241
1.519ProPro: 1.519 ± 0.439
1.953ProGln: 1.953 ± 1.196
1.519ProArg: 1.519 ± 0.67
5.858ProSer: 5.858 ± 1.822
2.387ProThr: 2.387 ± 0.738
3.255ProVal: 3.255 ± 0.886
0.0ProTrp: 0.0 ± 0.0
1.736ProTyr: 1.736 ± 0.45
0.0ProXaa: 0.0 ± 0.0
Gln
3.038GlnAla: 3.038 ± 1.173
0.434GlnCys: 0.434 ± 0.261
1.519GlnAsp: 1.519 ± 0.392
2.387GlnGlu: 2.387 ± 0.698
2.387GlnPhe: 2.387 ± 0.525
1.953GlnGly: 1.953 ± 0.584
0.868GlnHis: 0.868 ± 0.37
3.471GlnIle: 3.471 ± 0.644
1.736GlnLys: 1.736 ± 0.528
4.556GlnLeu: 4.556 ± 0.76
1.736GlnMet: 1.736 ± 0.397
1.736GlnAsn: 1.736 ± 0.69
1.302GlnPro: 1.302 ± 0.451
1.953GlnGln: 1.953 ± 0.864
1.953GlnArg: 1.953 ± 0.632
1.953GlnSer: 1.953 ± 1.205
3.255GlnThr: 3.255 ± 0.676
3.255GlnVal: 3.255 ± 0.831
0.434GlnTrp: 0.434 ± 0.218
1.302GlnTyr: 1.302 ± 0.42
0.0GlnXaa: 0.0 ± 0.0
Arg
3.038ArgAla: 3.038 ± 0.711
0.868ArgCys: 0.868 ± 0.188
1.519ArgAsp: 1.519 ± 0.53
3.038ArgGlu: 3.038 ± 1.136
1.953ArgPhe: 1.953 ± 0.603
3.255ArgGly: 3.255 ± 0.492
1.085ArgHis: 1.085 ± 0.652
3.471ArgIle: 3.471 ± 0.654
1.736ArgLys: 1.736 ± 0.232
6.292ArgLeu: 6.292 ± 0.764
1.085ArgMet: 1.085 ± 0.345
3.038ArgAsn: 3.038 ± 0.383
2.387ArgPro: 2.387 ± 0.664
1.736ArgGln: 1.736 ± 0.647
2.387ArgArg: 2.387 ± 0.789
3.905ArgSer: 3.905 ± 1.451
1.953ArgThr: 1.953 ± 0.542
3.471ArgVal: 3.471 ± 1.181
0.217ArgTrp: 0.217 ± 0.229
1.302ArgTyr: 1.302 ± 0.445
0.0ArgXaa: 0.0 ± 0.0
Ser
5.641SerAla: 5.641 ± 1.041
2.387SerCys: 2.387 ± 0.206
4.122SerAsp: 4.122 ± 0.92
3.688SerGlu: 3.688 ± 1.371
2.604SerPhe: 2.604 ± 1.243
6.075SerGly: 6.075 ± 1.332
1.085SerHis: 1.085 ± 0.475
9.98SerIle: 9.98 ± 1.158
4.556SerLys: 4.556 ± 0.948
6.943SerLeu: 6.943 ± 0.955
2.604SerMet: 2.604 ± 0.77
3.688SerAsn: 3.688 ± 0.907
5.858SerPro: 5.858 ± 1.212
5.641SerGln: 5.641 ± 1.379
4.556SerArg: 4.556 ± 1.029
8.679SerSer: 8.679 ± 2.274
5.207SerThr: 5.207 ± 1.195
3.905SerVal: 3.905 ± 1.369
1.302SerTrp: 1.302 ± 0.529
2.604SerTyr: 2.604 ± 0.523
0.0SerXaa: 0.0 ± 0.0
Thr
3.688ThrAla: 3.688 ± 1.203
1.736ThrCys: 1.736 ± 0.448
3.038ThrAsp: 3.038 ± 1.011
2.604ThrGlu: 2.604 ± 0.505
1.736ThrPhe: 1.736 ± 0.578
4.122ThrGly: 4.122 ± 0.927
1.085ThrHis: 1.085 ± 0.56
3.905ThrIle: 3.905 ± 0.501
3.688ThrLys: 3.688 ± 0.408
7.16ThrLeu: 7.16 ± 1.536
1.953ThrMet: 1.953 ± 0.675
2.604ThrAsn: 2.604 ± 0.325
4.556ThrPro: 4.556 ± 1.392
2.604ThrGln: 2.604 ± 0.49
2.821ThrArg: 2.821 ± 0.59
4.339ThrSer: 4.339 ± 1.753
4.773ThrThr: 4.773 ± 0.44
3.688ThrVal: 3.688 ± 0.721
0.868ThrTrp: 0.868 ± 0.351
1.302ThrTyr: 1.302 ± 0.539
0.0ThrXaa: 0.0 ± 0.0
Val
3.471ValAla: 3.471 ± 1.205
0.434ValCys: 0.434 ± 0.21
3.038ValAsp: 3.038 ± 0.81
1.519ValGlu: 1.519 ± 0.5
1.736ValPhe: 1.736 ± 0.599
4.556ValGly: 4.556 ± 0.662
1.519ValHis: 1.519 ± 0.492
5.207ValIle: 5.207 ± 0.838
3.255ValLys: 3.255 ± 0.743
5.858ValLeu: 5.858 ± 1.094
0.868ValMet: 0.868 ± 0.33
1.302ValAsn: 1.302 ± 0.864
2.17ValPro: 2.17 ± 0.855
2.387ValGln: 2.387 ± 0.441
2.821ValArg: 2.821 ± 0.732
5.858ValSer: 5.858 ± 1.079
3.471ValThr: 3.471 ± 0.413
2.604ValVal: 2.604 ± 0.966
0.434ValTrp: 0.434 ± 0.512
2.17ValTyr: 2.17 ± 0.843
0.0ValXaa: 0.0 ± 0.0
Trp
0.434TrpAla: 0.434 ± 0.261
0.217TrpCys: 0.217 ± 0.256
0.434TrpAsp: 0.434 ± 0.218
0.434TrpGlu: 0.434 ± 0.39
0.868TrpPhe: 0.868 ± 0.451
0.217TrpGly: 0.217 ± 0.13
0.0TrpHis: 0.0 ± 0.0
0.651TrpIle: 0.651 ± 0.391
0.434TrpLys: 0.434 ± 0.261
0.868TrpLeu: 0.868 ± 0.345
0.0TrpMet: 0.0 ± 0.0
0.217TrpAsn: 0.217 ± 0.13
0.434TrpPro: 0.434 ± 0.225
0.0TrpGln: 0.0 ± 0.0
1.085TrpArg: 1.085 ± 0.346
1.519TrpSer: 1.519 ± 0.543
0.217TrpThr: 0.217 ± 0.256
0.217TrpVal: 0.217 ± 0.229
0.0TrpTrp: 0.0 ± 0.0
0.434TrpTyr: 0.434 ± 0.225
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.868TyrAla: 0.868 ± 0.351
0.651TyrCys: 0.651 ± 0.265
1.302TyrAsp: 1.302 ± 0.42
1.085TyrGlu: 1.085 ± 0.331
1.085TyrPhe: 1.085 ± 0.474
1.953TyrGly: 1.953 ± 0.852
0.217TyrHis: 0.217 ± 0.272
1.302TyrIle: 1.302 ± 0.339
1.302TyrLys: 1.302 ± 0.63
2.17TyrLeu: 2.17 ± 1.077
1.302TyrMet: 1.302 ± 0.42
3.255TyrAsn: 3.255 ± 0.445
1.519TyrPro: 1.519 ± 0.767
1.953TyrGln: 1.953 ± 0.659
1.302TyrArg: 1.302 ± 0.48
3.255TyrSer: 3.255 ± 0.673
2.17TyrThr: 2.17 ± 1.12
1.519TyrVal: 1.519 ± 0.416
0.434TyrTrp: 0.434 ± 0.218
1.302TyrTyr: 1.302 ± 0.608
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4610 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski