Amino acid dipepetide frequency for Gull circovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.36AlaAla: 4.36 ± 1.501
0.0AlaCys: 0.0 ± 0.0
2.907AlaAsp: 2.907 ± 2.053
1.453AlaGlu: 1.453 ± 1.086
4.36AlaPhe: 4.36 ± 1.501
5.814AlaGly: 5.814 ± 2.491
1.453AlaHis: 1.453 ± 1.027
2.907AlaIle: 2.907 ± 1.366
1.453AlaLys: 1.453 ± 1.086
4.36AlaLeu: 4.36 ± 0.873
0.0AlaMet: 0.0 ± 0.0
2.907AlaAsn: 2.907 ± 0.814
1.453AlaPro: 1.453 ± 1.635
1.453AlaGln: 1.453 ± 1.086
13.081AlaArg: 13.081 ± 2.154
4.36AlaSer: 4.36 ± 3.259
1.453AlaThr: 1.453 ± 1.635
2.907AlaVal: 2.907 ± 2.053
2.907AlaTrp: 2.907 ± 2.173
1.453AlaTyr: 1.453 ± 1.027
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.453CysAsp: 1.453 ± 1.027
1.453CysGlu: 1.453 ± 1.027
1.453CysPhe: 1.453 ± 1.027
2.907CysGly: 2.907 ± 2.053
1.453CysHis: 1.453 ± 1.635
1.453CysIle: 1.453 ± 1.635
0.0CysLys: 0.0 ± 0.0
2.907CysLeu: 2.907 ± 0.814
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.453CysPro: 1.453 ± 1.027
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.453AspAla: 1.453 ± 1.086
4.36AspCys: 4.36 ± 3.231
1.453AspAsp: 1.453 ± 1.027
1.453AspGlu: 1.453 ± 1.635
7.267AspPhe: 7.267 ± 2.326
7.267AspGly: 7.267 ± 2.186
0.0AspHis: 0.0 ± 0.0
2.907AspIle: 2.907 ± 0.814
1.453AspLys: 1.453 ± 1.027
7.267AspLeu: 7.267 ± 0.424
2.907AspMet: 2.907 ± 0.814
4.36AspAsn: 4.36 ± 1.501
4.36AspPro: 4.36 ± 2.442
2.907AspGln: 2.907 ± 0.814
1.453AspArg: 1.453 ± 1.027
2.907AspSer: 2.907 ± 1.366
0.0AspThr: 0.0 ± 0.0
0.0AspVal: 0.0 ± 0.0
4.36AspTrp: 4.36 ± 0.873
2.907AspTyr: 2.907 ± 0.814
0.0AspXaa: 0.0 ± 0.0
Glu
1.453GluAla: 1.453 ± 1.027
1.453GluCys: 1.453 ± 1.027
2.907GluAsp: 2.907 ± 2.173
5.814GluGlu: 5.814 ± 2.44
7.267GluPhe: 7.267 ± 3.003
7.267GluGly: 7.267 ± 2.598
1.453GluHis: 1.453 ± 1.635
5.814GluIle: 5.814 ± 2.44
4.36GluLys: 4.36 ± 1.501
1.453GluLeu: 1.453 ± 1.635
1.453GluMet: 1.453 ± 1.027
1.453GluAsn: 1.453 ± 1.635
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
0.0GluArg: 0.0 ± 0.0
1.453GluSer: 1.453 ± 1.027
2.907GluThr: 2.907 ± 2.053
4.36GluVal: 4.36 ± 3.08
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.907PheAla: 2.907 ± 0.814
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
2.907PheGlu: 2.907 ± 0.814
1.453PhePhe: 1.453 ± 1.086
1.453PheGly: 1.453 ± 1.086
2.907PheHis: 2.907 ± 3.269
2.907PheIle: 2.907 ± 1.772
5.814PheLys: 5.814 ± 2.44
2.907PheLeu: 2.907 ± 1.366
0.0PheMet: 0.0 ± 0.0
2.907PheAsn: 2.907 ± 1.772
4.36PhePro: 4.36 ± 0.873
0.0PheGln: 0.0 ± 0.0
4.36PheArg: 4.36 ± 3.259
4.36PheSer: 4.36 ± 1.623
10.174PheThr: 10.174 ± 1.208
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
5.814PheTyr: 5.814 ± 4.106
0.0PheXaa: 0.0 ± 0.0
Gly
7.267GlyAla: 7.267 ± 1.527
2.907GlyCys: 2.907 ± 2.053
2.907GlyAsp: 2.907 ± 0.814
7.267GlyGlu: 7.267 ± 3.478
2.907GlyPhe: 2.907 ± 0.814
1.453GlyGly: 1.453 ± 1.635
4.36GlyHis: 4.36 ± 0.873
1.453GlyIle: 1.453 ± 1.086
5.814GlyLys: 5.814 ± 2.565
2.907GlyLeu: 2.907 ± 0.814
0.0GlyMet: 0.0 ± 0.0
0.0GlyAsn: 0.0 ± 0.0
1.453GlyPro: 1.453 ± 1.027
2.907GlyGln: 2.907 ± 2.173
4.36GlyArg: 4.36 ± 1.78
5.814GlySer: 5.814 ± 2.44
8.721GlyThr: 8.721 ± 1.746
2.907GlyVal: 2.907 ± 1.772
5.814GlyTrp: 5.814 ± 1.629
2.907GlyTyr: 2.907 ± 0.814
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.453HisGlu: 1.453 ± 1.027
2.907HisPhe: 2.907 ± 2.053
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.453HisIle: 1.453 ± 1.635
0.0HisLys: 0.0 ± 0.0
1.453HisLeu: 1.453 ± 1.027
2.907HisMet: 2.907 ± 1.366
1.453HisAsn: 1.453 ± 1.635
2.907HisPro: 2.907 ± 1.366
0.0HisGln: 0.0 ± 0.0
5.814HisArg: 5.814 ± 1.421
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
5.814HisVal: 5.814 ± 4.419
0.0HisTrp: 0.0 ± 0.0
1.453HisTyr: 1.453 ± 1.086
0.0HisXaa: 0.0 ± 0.0
Ile
5.814IleAla: 5.814 ± 1.421
0.0IleCys: 0.0 ± 0.0
5.814IleAsp: 5.814 ± 2.491
1.453IleGlu: 1.453 ± 1.027
0.0IlePhe: 0.0 ± 0.0
7.267IleGly: 7.267 ± 3.429
1.453IleHis: 1.453 ± 1.635
4.36IleIle: 4.36 ± 1.78
1.453IleLys: 1.453 ± 1.635
2.907IleLeu: 2.907 ± 1.366
2.907IleMet: 2.907 ± 0.814
4.36IleAsn: 4.36 ± 1.501
1.453IlePro: 1.453 ± 1.086
0.0IleGln: 0.0 ± 0.0
0.0IleArg: 0.0 ± 0.0
2.907IleSer: 2.907 ± 1.772
2.907IleThr: 2.907 ± 2.173
4.36IleVal: 4.36 ± 3.08
0.0IleTrp: 0.0 ± 0.0
2.907IleTyr: 2.907 ± 2.173
0.0IleXaa: 0.0 ± 0.0
Lys
1.453LysAla: 1.453 ± 1.027
0.0LysCys: 0.0 ± 0.0
7.267LysAsp: 7.267 ± 0.424
1.453LysGlu: 1.453 ± 1.027
4.36LysPhe: 4.36 ± 1.501
4.36LysGly: 4.36 ± 3.08
1.453LysHis: 1.453 ± 1.635
1.453LysIle: 1.453 ± 1.027
4.36LysLys: 4.36 ± 1.501
5.814LysLeu: 5.814 ± 0.703
1.453LysMet: 1.453 ± 1.027
0.0LysAsn: 0.0 ± 0.0
2.907LysPro: 2.907 ± 0.814
4.36LysGln: 4.36 ± 1.78
2.907LysArg: 2.907 ± 0.814
4.36LysSer: 4.36 ± 1.501
2.907LysThr: 2.907 ± 0.814
1.453LysVal: 1.453 ± 1.086
1.453LysTrp: 1.453 ± 1.086
2.907LysTyr: 2.907 ± 2.053
0.0LysXaa: 0.0 ± 0.0
Leu
10.174LeuAla: 10.174 ± 2.093
1.453LeuCys: 1.453 ± 1.027
1.453LeuAsp: 1.453 ± 1.635
1.453LeuGlu: 1.453 ± 1.635
4.36LeuPhe: 4.36 ± 0.873
0.0LeuGly: 0.0 ± 0.0
1.453LeuHis: 1.453 ± 1.027
5.814LeuIle: 5.814 ± 2.732
4.36LeuLys: 4.36 ± 1.623
4.36LeuLeu: 4.36 ± 2.832
0.0LeuMet: 0.0 ± 0.971
8.721LeuAsn: 8.721 ± 3.107
5.814LeuPro: 5.814 ± 1.629
4.36LeuGln: 4.36 ± 1.623
14.535LeuArg: 14.535 ± 4.039
1.453LeuSer: 1.453 ± 1.086
7.267LeuThr: 7.267 ± 2.186
4.36LeuVal: 4.36 ± 2.442
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.907MetAla: 2.907 ± 1.366
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.453MetGlu: 1.453 ± 1.027
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.453MetIle: 1.453 ± 1.027
1.453MetLys: 1.453 ± 1.027
4.36MetLeu: 4.36 ± 0.873
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.907MetPro: 2.907 ± 0.814
0.0MetGln: 0.0 ± 0.0
4.36MetArg: 4.36 ± 0.873
1.453MetSer: 1.453 ± 1.027
1.453MetThr: 1.453 ± 1.086
0.0MetVal: 0.0 ± 0.0
1.453MetTrp: 1.453 ± 1.086
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.453AsnAla: 1.453 ± 1.027
0.0AsnCys: 0.0 ± 0.0
2.907AsnAsp: 2.907 ± 1.772
2.907AsnGlu: 2.907 ± 0.814
4.36AsnPhe: 4.36 ± 3.231
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
2.907AsnLys: 2.907 ± 1.366
5.814AsnLeu: 5.814 ± 2.639
0.0AsnMet: 0.0 ± 0.0
1.453AsnAsn: 1.453 ± 1.027
0.0AsnPro: 0.0 ± 0.0
1.453AsnGln: 1.453 ± 1.027
4.36AsnArg: 4.36 ± 1.623
2.907AsnSer: 2.907 ± 1.772
0.0AsnThr: 0.0 ± 0.0
2.907AsnVal: 2.907 ± 0.814
1.453AsnTrp: 1.453 ± 1.086
2.907AsnTyr: 2.907 ± 2.053
0.0AsnXaa: 0.0 ± 0.0
Pro
2.907ProAla: 2.907 ± 2.173
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
4.36ProGlu: 4.36 ± 0.873
1.453ProPhe: 1.453 ± 1.086
4.36ProGly: 4.36 ± 1.501
4.36ProHis: 4.36 ± 3.08
2.907ProIle: 2.907 ± 1.366
1.453ProLys: 1.453 ± 1.086
4.36ProLeu: 4.36 ± 2.442
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
5.814ProPro: 5.814 ± 2.732
2.907ProGln: 2.907 ± 2.173
5.814ProArg: 5.814 ± 2.44
7.267ProSer: 7.267 ± 0.424
0.0ProThr: 0.0 ± 0.0
4.36ProVal: 4.36 ± 0.873
0.0ProTrp: 0.0 ± 0.0
1.453ProTyr: 1.453 ± 1.027
0.0ProXaa: 0.0 ± 0.0
Gln
1.453GlnAla: 1.453 ± 1.086
0.0GlnCys: 0.0 ± 0.0
5.814GlnAsp: 5.814 ± 2.639
1.453GlnGlu: 1.453 ± 1.086
2.907GlnPhe: 2.907 ± 2.173
1.453GlnGly: 1.453 ± 1.027
0.0GlnHis: 0.0 ± 0.0
1.453GlnIle: 1.453 ± 1.086
2.907GlnLys: 2.907 ± 0.814
1.453GlnLeu: 1.453 ± 1.086
2.907GlnMet: 2.907 ± 0.814
1.453GlnAsn: 1.453 ± 1.027
0.0GlnPro: 0.0 ± 0.0
1.453GlnGln: 1.453 ± 1.027
2.907GlnArg: 2.907 ± 0.814
1.453GlnSer: 1.453 ± 1.635
2.907GlnThr: 2.907 ± 1.772
1.453GlnVal: 1.453 ± 1.635
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.814ArgAla: 5.814 ± 2.491
0.0ArgCys: 0.0 ± 0.0
8.721ArgAsp: 8.721 ± 2.014
4.36ArgGlu: 4.36 ± 2.832
1.453ArgPhe: 1.453 ± 1.086
8.721ArgGly: 8.721 ± 2.443
2.907ArgHis: 2.907 ± 0.814
4.36ArgIle: 4.36 ± 1.623
0.0ArgLys: 0.0 ± 0.0
10.174ArgLeu: 10.174 ± 0.961
0.0ArgMet: 0.0 ± 0.0
2.907ArgAsn: 2.907 ± 0.814
4.36ArgPro: 4.36 ± 1.623
4.36ArgGln: 4.36 ± 2.442
11.628ArgArg: 11.628 ± 1.939
7.267ArgSer: 7.267 ± 1.527
0.0ArgThr: 0.0 ± 0.0
7.267ArgVal: 7.267 ± 2.598
1.453ArgTrp: 1.453 ± 1.027
5.814ArgTyr: 5.814 ± 0.703
0.0ArgXaa: 0.0 ± 0.0
Ser
2.907SerAla: 2.907 ± 0.814
0.0SerCys: 0.0 ± 0.0
7.267SerAsp: 7.267 ± 2.186
4.36SerGlu: 4.36 ± 1.501
0.0SerPhe: 0.0 ± 0.0
8.721SerGly: 8.721 ± 2.014
0.0SerHis: 0.0 ± 0.0
1.453SerIle: 1.453 ± 1.027
8.721SerLys: 8.721 ± 0.669
5.814SerLeu: 5.814 ± 4.805
1.453SerMet: 1.453 ± 1.086
2.907SerAsn: 2.907 ± 0.814
1.453SerPro: 1.453 ± 1.086
1.453SerGln: 1.453 ± 1.027
5.814SerArg: 5.814 ± 2.491
2.907SerSer: 2.907 ± 1.772
0.0SerThr: 0.0 ± 0.0
1.453SerVal: 1.453 ± 1.635
1.453SerTrp: 1.453 ± 1.086
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.36ThrAla: 4.36 ± 1.501
0.0ThrCys: 0.0 ± 0.0
2.907ThrAsp: 2.907 ± 2.173
1.453ThrGlu: 1.453 ± 1.027
5.814ThrPhe: 5.814 ± 3.543
1.453ThrGly: 1.453 ± 1.027
1.453ThrHis: 1.453 ± 1.027
5.814ThrIle: 5.814 ± 4.345
0.0ThrLys: 0.0 ± 0.0
2.907ThrLeu: 2.907 ± 1.366
4.36ThrMet: 4.36 ± 2.396
0.0ThrAsn: 0.0 ± 0.0
4.36ThrPro: 4.36 ± 3.08
4.36ThrGln: 4.36 ± 2.442
2.907ThrArg: 2.907 ± 1.772
4.36ThrSer: 4.36 ± 1.78
2.907ThrThr: 2.907 ± 2.173
2.907ThrVal: 2.907 ± 2.173
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.453ValAla: 1.453 ± 1.027
0.0ValCys: 0.0 ± 0.0
2.907ValAsp: 2.907 ± 0.814
2.907ValGlu: 2.907 ± 1.366
2.907ValPhe: 2.907 ± 1.366
5.814ValGly: 5.814 ± 2.491
2.907ValHis: 2.907 ± 1.772
2.907ValIle: 2.907 ± 2.053
5.814ValLys: 5.814 ± 2.44
4.36ValLeu: 4.36 ± 0.873
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
4.36ValPro: 4.36 ± 0.873
1.453ValGln: 1.453 ± 1.086
4.36ValArg: 4.36 ± 2.442
2.907ValSer: 2.907 ± 3.269
4.36ValThr: 4.36 ± 2.442
5.814ValVal: 5.814 ± 3.34
0.0ValTrp: 0.0 ± 0.0
2.907ValTyr: 2.907 ± 2.053
0.0ValXaa: 0.0 ± 0.0
Trp
1.453TrpAla: 1.453 ± 1.086
1.453TrpCys: 1.453 ± 1.027
2.907TrpAsp: 2.907 ± 0.814
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.453TrpGly: 1.453 ± 1.086
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.453TrpLys: 1.453 ± 1.027
4.36TrpLeu: 4.36 ± 1.623
0.0TrpMet: 0.0 ± 0.0
2.907TrpAsn: 2.907 ± 2.173
2.907TrpPro: 2.907 ± 2.173
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
1.453TrpVal: 1.453 ± 1.635
2.907TrpTrp: 2.907 ± 2.053
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.453TyrAla: 1.453 ± 1.027
2.907TyrCys: 2.907 ± 2.053
1.453TyrAsp: 1.453 ± 1.027
1.453TyrGlu: 1.453 ± 1.027
0.0TyrPhe: 0.0 ± 0.0
4.36TyrGly: 4.36 ± 1.501
0.0TyrHis: 0.0 ± 0.0
1.453TyrIle: 1.453 ± 1.086
2.907TyrLys: 2.907 ± 2.053
2.907TyrLeu: 2.907 ± 0.814
1.453TyrMet: 1.453 ± 0.896
0.0TyrAsn: 0.0 ± 0.0
1.453TyrPro: 1.453 ± 1.027
0.0TyrGln: 0.0 ± 0.0
2.907TyrArg: 2.907 ± 0.814
0.0TyrSer: 0.0 ± 0.0
4.36TyrThr: 4.36 ± 0.873
4.36TyrVal: 4.36 ± 1.501
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (689 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski