Amino acid dipepetide frequency for Cactus virus X

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.474AlaAla: 5.474 ± 2.446
0.0AlaCys: 0.0 ± 0.0
2.947AlaAsp: 2.947 ± 1.088
3.368AlaGlu: 3.368 ± 1.313
2.947AlaPhe: 2.947 ± 1.102
5.895AlaGly: 5.895 ± 1.707
1.263AlaHis: 1.263 ± 0.666
4.211AlaIle: 4.211 ± 0.781
3.368AlaLys: 3.368 ± 1.293
10.526AlaLeu: 10.526 ± 5.839
1.684AlaMet: 1.684 ± 0.888
4.632AlaAsn: 4.632 ± 1.205
2.526AlaPro: 2.526 ± 1.399
2.105AlaGln: 2.105 ± 1.109
3.368AlaArg: 3.368 ± 1.309
2.947AlaSer: 2.947 ± 0.736
6.316AlaThr: 6.316 ± 1.99
2.526AlaVal: 2.526 ± 1.144
1.684AlaTrp: 1.684 ± 1.268
2.105AlaTyr: 2.105 ± 0.77
0.0AlaXaa: 0.0 ± 0.0
Cys
1.684CysAla: 1.684 ± 0.672
0.421CysCys: 0.421 ± 0.222
0.421CysAsp: 0.421 ± 0.222
2.105CysGlu: 2.105 ± 0.805
0.421CysPhe: 0.421 ± 0.732
0.842CysGly: 0.842 ± 0.776
0.421CysHis: 0.421 ± 0.732
0.0CysIle: 0.0 ± 0.0
0.421CysLys: 0.421 ± 0.222
1.263CysLeu: 1.263 ± 0.778
0.0CysMet: 0.0 ± 0.0
1.263CysAsn: 1.263 ± 0.544
0.842CysPro: 0.842 ± 1.154
0.421CysGln: 0.421 ± 0.222
0.842CysArg: 0.842 ± 0.634
2.947CysSer: 2.947 ± 3.039
0.842CysThr: 0.842 ± 0.444
0.421CysVal: 0.421 ± 0.222
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.526AspAla: 2.526 ± 1.257
0.842AspCys: 0.842 ± 0.444
2.105AspAsp: 2.105 ± 1.11
2.947AspGlu: 2.947 ± 1.095
4.211AspPhe: 4.211 ± 1.698
2.526AspGly: 2.526 ± 1.319
1.263AspHis: 1.263 ± 0.684
1.263AspIle: 1.263 ± 0.666
2.526AspLys: 2.526 ± 0.94
2.947AspLeu: 2.947 ± 1.135
0.421AspMet: 0.421 ± 0.429
0.842AspAsn: 0.842 ± 0.634
3.789AspPro: 3.789 ± 1.548
1.263AspGln: 1.263 ± 0.96
0.842AspArg: 0.842 ± 0.444
5.474AspSer: 5.474 ± 0.789
2.105AspThr: 2.105 ± 0.92
1.684AspVal: 1.684 ± 0.809
0.421AspTrp: 0.421 ± 0.222
1.263AspTyr: 1.263 ± 0.507
0.0AspXaa: 0.0 ± 0.0
Glu
4.632GluAla: 4.632 ± 1.796
0.842GluCys: 0.842 ± 0.444
2.526GluAsp: 2.526 ± 1.014
3.789GluGlu: 3.789 ± 1.998
0.842GluPhe: 0.842 ± 0.444
2.947GluGly: 2.947 ± 1.554
2.947GluHis: 2.947 ± 1.181
1.263GluIle: 1.263 ± 0.606
4.632GluLys: 4.632 ± 2.443
4.632GluLeu: 4.632 ± 1.384
1.263GluMet: 1.263 ± 0.88
2.526GluAsn: 2.526 ± 1.332
2.526GluPro: 2.526 ± 0.94
1.684GluGln: 1.684 ± 0.682
2.105GluArg: 2.105 ± 0.774
4.632GluSer: 4.632 ± 2.135
5.053GluThr: 5.053 ± 1.354
2.947GluVal: 2.947 ± 1.554
0.842GluTrp: 0.842 ± 0.444
0.421GluTyr: 0.421 ± 0.577
0.0GluXaa: 0.0 ± 0.0
Phe
2.947PheAla: 2.947 ± 1.385
0.842PheCys: 0.842 ± 0.634
3.789PheAsp: 3.789 ± 1.818
2.947PheGlu: 2.947 ± 0.66
2.526PhePhe: 2.526 ± 0.777
1.684PheGly: 1.684 ± 0.606
1.263PheHis: 1.263 ± 0.666
1.684PheIle: 1.684 ± 0.606
2.526PheLys: 2.526 ± 0.924
4.632PheLeu: 4.632 ± 0.816
1.263PheMet: 1.263 ± 0.666
1.684PheAsn: 1.684 ± 0.857
2.105PhePro: 2.105 ± 1.497
3.789PheGln: 3.789 ± 0.733
0.842PheArg: 0.842 ± 0.444
4.632PheSer: 4.632 ± 1.473
3.368PheThr: 3.368 ± 1.776
1.263PheVal: 1.263 ± 0.684
1.684PheTrp: 1.684 ± 0.888
0.842PheTyr: 0.842 ± 0.776
0.0PheXaa: 0.0 ± 0.0
Gly
5.053GlyAla: 5.053 ± 0.798
1.263GlyCys: 1.263 ± 1.077
4.211GlyAsp: 4.211 ± 1.001
1.263GlyGlu: 1.263 ± 0.666
1.684GlyPhe: 1.684 ± 0.888
2.526GlyGly: 2.526 ± 0.812
1.684GlyHis: 1.684 ± 0.888
2.947GlyIle: 2.947 ± 0.954
2.947GlyLys: 2.947 ± 1.135
5.474GlyLeu: 5.474 ± 2.931
0.421GlyMet: 0.421 ± 0.222
2.105GlyAsn: 2.105 ± 0.917
4.632GlyPro: 4.632 ± 1.627
2.526GlyGln: 2.526 ± 1.332
2.105GlyArg: 2.105 ± 0.84
5.053GlySer: 5.053 ± 1.908
2.526GlyThr: 2.526 ± 1.643
4.211GlyVal: 4.211 ± 2.395
0.842GlyTrp: 0.842 ± 1.279
0.842GlyTyr: 0.842 ± 0.496
0.0GlyXaa: 0.0 ± 0.0
His
1.263HisAla: 1.263 ± 0.507
2.105HisCys: 2.105 ± 0.705
0.842HisAsp: 0.842 ± 0.444
1.684HisGlu: 1.684 ± 0.888
3.789HisPhe: 3.789 ± 1.355
2.105HisGly: 2.105 ± 0.732
2.105HisHis: 2.105 ± 0.77
1.684HisIle: 1.684 ± 0.809
2.105HisLys: 2.105 ± 1.11
2.105HisLeu: 2.105 ± 0.77
0.842HisMet: 0.842 ± 0.444
0.842HisAsn: 0.842 ± 0.444
2.947HisPro: 2.947 ± 1.695
2.947HisGln: 2.947 ± 1.135
1.684HisArg: 1.684 ± 0.606
2.526HisSer: 2.526 ± 0.68
3.789HisThr: 3.789 ± 3.079
0.421HisVal: 0.421 ± 0.577
0.421HisTrp: 0.421 ± 0.222
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.632IleAla: 4.632 ± 1.462
0.842IleCys: 0.842 ± 0.857
0.842IleAsp: 0.842 ± 0.634
3.789IleGlu: 3.789 ± 1.998
1.684IlePhe: 1.684 ± 0.841
2.105IleGly: 2.105 ± 0.805
2.105IleHis: 2.105 ± 0.759
2.526IleIle: 2.526 ± 0.924
4.632IleLys: 4.632 ± 1.974
5.053IleLeu: 5.053 ± 1.427
2.105IleMet: 2.105 ± 1.11
2.105IleAsn: 2.105 ± 0.705
2.526IlePro: 2.526 ± 0.922
3.789IleGln: 3.789 ± 1.493
0.842IleArg: 0.842 ± 1.154
3.368IleSer: 3.368 ± 1.605
4.632IleThr: 4.632 ± 1.336
2.947IleVal: 2.947 ± 0.737
0.421IleTrp: 0.421 ± 0.732
1.263IleTyr: 1.263 ± 0.507
0.0IleXaa: 0.0 ± 0.0
Lys
5.474LysAla: 5.474 ± 2.072
0.842LysCys: 0.842 ± 0.444
2.947LysAsp: 2.947 ± 1.554
5.053LysGlu: 5.053 ± 1.496
1.684LysPhe: 1.684 ± 0.656
4.632LysGly: 4.632 ± 1.372
0.421LysHis: 0.421 ± 0.945
5.053LysIle: 5.053 ± 2.119
3.368LysLys: 3.368 ± 1.131
7.158LysLeu: 7.158 ± 2.684
2.105LysMet: 2.105 ± 0.759
2.526LysAsn: 2.526 ± 1.212
4.632LysPro: 4.632 ± 1.739
2.526LysGln: 2.526 ± 1.332
1.263LysArg: 1.263 ± 0.544
2.947LysSer: 2.947 ± 1.102
4.211LysThr: 4.211 ± 1.386
2.526LysVal: 2.526 ± 1.332
0.421LysTrp: 0.421 ± 0.222
0.842LysTyr: 0.842 ± 0.857
0.0LysXaa: 0.0 ± 0.0
Leu
7.579LeuAla: 7.579 ± 1.283
0.842LeuCys: 0.842 ± 0.496
3.789LeuAsp: 3.789 ± 1.355
4.211LeuGlu: 4.211 ± 1.081
5.053LeuPhe: 5.053 ± 1.9
8.0LeuGly: 8.0 ± 2.278
2.947LeuHis: 2.947 ± 1.095
5.053LeuIle: 5.053 ± 1.953
7.158LeuLys: 7.158 ± 2.353
6.316LeuLeu: 6.316 ± 2.256
0.842LeuMet: 0.842 ± 1.216
2.526LeuAsn: 2.526 ± 1.874
8.421LeuPro: 8.421 ± 1.392
4.211LeuGln: 4.211 ± 1.252
5.895LeuArg: 5.895 ± 1.711
9.263LeuSer: 9.263 ± 3.908
10.947LeuThr: 10.947 ± 3.87
4.632LeuVal: 4.632 ± 2.515
0.421LeuTrp: 0.421 ± 0.222
2.947LeuTyr: 2.947 ± 0.699
0.0LeuXaa: 0.0 ± 0.0
Met
0.842MetAla: 0.842 ± 0.444
0.421MetCys: 0.421 ± 0.222
0.842MetAsp: 0.842 ± 0.444
0.842MetGlu: 0.842 ± 0.921
1.684MetPhe: 1.684 ± 0.809
1.263MetGly: 1.263 ± 0.666
0.0MetHis: 0.0 ± 0.0
2.105MetIle: 2.105 ± 0.633
1.263MetLys: 1.263 ± 0.544
2.947MetLeu: 2.947 ± 1.11
0.421MetMet: 0.421 ± 0.222
0.421MetAsn: 0.421 ± 0.222
2.947MetPro: 2.947 ± 1.054
0.0MetGln: 0.0 ± 0.0
1.684MetArg: 1.684 ± 0.843
1.263MetSer: 1.263 ± 1.042
1.684MetThr: 1.684 ± 1.111
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.684MetTyr: 1.684 ± 0.888
0.0MetXaa: 0.0 ± 0.0
Asn
2.105AsnAla: 2.105 ± 0.943
1.263AsnCys: 1.263 ± 0.666
2.947AsnAsp: 2.947 ± 1.554
2.526AsnGlu: 2.526 ± 1.212
2.105AsnPhe: 2.105 ± 1.11
2.105AsnGly: 2.105 ± 0.626
1.684AsnHis: 1.684 ± 0.841
2.526AsnIle: 2.526 ± 0.67
2.947AsnLys: 2.947 ± 1.367
3.368AsnLeu: 3.368 ± 1.077
0.842AsnMet: 0.842 ± 0.444
1.263AsnAsn: 1.263 ± 0.778
3.789AsnPro: 3.789 ± 1.493
1.684AsnGln: 1.684 ± 0.834
2.947AsnArg: 2.947 ± 1.107
2.105AsnSer: 2.105 ± 1.077
1.684AsnThr: 1.684 ± 0.809
0.842AsnVal: 0.842 ± 0.634
0.421AsnTrp: 0.421 ± 0.913
2.105AsnTyr: 2.105 ± 1.22
0.0AsnXaa: 0.0 ± 0.0
Pro
4.632ProAla: 4.632 ± 1.433
1.263ProCys: 1.263 ± 1.02
2.947ProAsp: 2.947 ± 1.655
6.316ProGlu: 6.316 ± 2.025
2.105ProPhe: 2.105 ± 0.807
3.789ProGly: 3.789 ± 1.141
4.632ProHis: 4.632 ± 2.09
6.316ProIle: 6.316 ± 1.082
5.895ProLys: 5.895 ± 0.907
8.0ProLeu: 8.0 ± 2.068
0.842ProMet: 0.842 ± 0.555
2.947ProAsn: 2.947 ± 0.722
5.053ProPro: 5.053 ± 3.73
1.263ProGln: 1.263 ± 0.606
2.105ProArg: 2.105 ± 1.472
5.053ProSer: 5.053 ± 1.017
5.474ProThr: 5.474 ± 1.585
1.684ProVal: 1.684 ± 0.606
1.684ProTrp: 1.684 ± 0.843
1.263ProTyr: 1.263 ± 0.666
0.0ProXaa: 0.0 ± 0.0
Gln
3.368GlnAla: 3.368 ± 1.293
0.0GlnCys: 0.0 ± 0.0
1.263GlnAsp: 1.263 ± 0.666
1.684GlnGlu: 1.684 ± 0.888
2.526GlnPhe: 2.526 ± 2.154
1.684GlnGly: 1.684 ± 0.656
2.105GlnHis: 2.105 ± 0.978
1.684GlnIle: 1.684 ± 0.888
2.105GlnLys: 2.105 ± 1.22
4.632GlnLeu: 4.632 ± 1.423
0.842GlnMet: 0.842 ± 0.634
1.263GlnAsn: 1.263 ± 0.666
4.211GlnPro: 4.211 ± 1.341
2.105GlnGln: 2.105 ± 1.11
2.947GlnArg: 2.947 ± 0.869
3.368GlnSer: 3.368 ± 1.819
3.368GlnThr: 3.368 ± 1.077
3.368GlnVal: 3.368 ± 1.212
0.842GlnTrp: 0.842 ± 0.444
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.526ArgAla: 2.526 ± 1.05
0.421ArgCys: 0.421 ± 0.577
2.105ArgAsp: 2.105 ± 1.257
1.263ArgGlu: 1.263 ± 0.666
1.263ArgPhe: 1.263 ± 1.024
1.263ArgGly: 1.263 ± 0.544
2.947ArgHis: 2.947 ± 1.095
1.263ArgIle: 1.263 ± 0.606
2.105ArgLys: 2.105 ± 1.128
5.895ArgLeu: 5.895 ± 1.385
0.842ArgMet: 0.842 ± 1.119
4.211ArgAsn: 4.211 ± 1.698
1.263ArgPro: 1.263 ± 1.186
3.789ArgGln: 3.789 ± 0.991
3.789ArgArg: 3.789 ± 1.619
3.789ArgSer: 3.789 ± 2.671
4.211ArgThr: 4.211 ± 1.949
2.526ArgVal: 2.526 ± 1.212
0.0ArgTrp: 0.0 ± 0.0
1.684ArgTyr: 1.684 ± 0.656
0.0ArgXaa: 0.0 ± 0.0
Ser
2.526SerAla: 2.526 ± 1.548
1.684SerCys: 1.684 ± 1.771
2.947SerAsp: 2.947 ± 1.554
2.526SerGlu: 2.526 ± 1.42
2.105SerPhe: 2.105 ± 0.896
4.632SerGly: 4.632 ± 2.307
2.947SerHis: 2.947 ± 2.14
2.947SerIle: 2.947 ± 1.102
5.053SerLys: 5.053 ± 0.616
9.263SerLeu: 9.263 ± 2.566
2.526SerMet: 2.526 ± 1.129
2.526SerAsn: 2.526 ± 0.657
8.421SerPro: 8.421 ± 4.51
4.632SerGln: 4.632 ± 1.894
3.789SerArg: 3.789 ± 3.143
7.579SerSer: 7.579 ± 4.921
5.895SerThr: 5.895 ± 1.785
2.105SerVal: 2.105 ± 0.705
1.684SerTrp: 1.684 ± 1.233
2.105SerTyr: 2.105 ± 0.705
0.0SerXaa: 0.0 ± 0.0
Thr
5.895ThrAla: 5.895 ± 1.747
0.842ThrCys: 0.842 ± 1.185
1.684ThrAsp: 1.684 ± 0.606
3.789ThrGlu: 3.789 ± 1.548
3.789ThrPhe: 3.789 ± 1.998
3.789ThrGly: 3.789 ± 1.485
2.947ThrHis: 2.947 ± 1.554
4.632ThrIle: 4.632 ± 1.473
4.211ThrLys: 4.211 ± 0.62
8.842ThrLeu: 8.842 ± 3.899
2.526ThrMet: 2.526 ± 0.917
2.947ThrAsn: 2.947 ± 1.154
8.842ThrPro: 8.842 ± 1.621
1.263ThrGln: 1.263 ± 0.82
3.789ThrArg: 3.789 ± 3.611
5.895ThrSer: 5.895 ± 2.519
5.474ThrThr: 5.474 ± 2.281
4.632ThrVal: 4.632 ± 1.172
1.684ThrTrp: 1.684 ± 0.843
2.526ThrTyr: 2.526 ± 1.024
0.0ThrXaa: 0.0 ± 0.0
Val
0.842ValAla: 0.842 ± 0.496
0.0ValCys: 0.0 ± 0.0
0.421ValAsp: 0.421 ± 0.222
1.684ValGlu: 1.684 ± 0.606
4.632ValPhe: 4.632 ± 1.385
1.263ValGly: 1.263 ± 0.684
2.105ValHis: 2.105 ± 0.77
3.368ValIle: 3.368 ± 1.715
1.684ValLys: 1.684 ± 1.417
3.789ValLeu: 3.789 ± 2.377
0.842ValMet: 0.842 ± 0.444
2.105ValAsn: 2.105 ± 0.77
1.684ValPro: 1.684 ± 0.656
2.526ValGln: 2.526 ± 0.924
5.053ValArg: 5.053 ± 1.127
2.526ValSer: 2.526 ± 1.319
4.211ValThr: 4.211 ± 1.252
4.211ValVal: 4.211 ± 2.555
0.421ValTrp: 0.421 ± 0.222
1.263ValTyr: 1.263 ± 0.666
0.0ValXaa: 0.0 ± 0.0
Trp
2.526TrpAla: 2.526 ± 0.775
0.0TrpCys: 0.0 ± 0.0
1.684TrpAsp: 1.684 ± 0.955
1.263TrpGlu: 1.263 ± 0.606
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.421TrpHis: 0.421 ± 0.222
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.263TrpLeu: 1.263 ± 0.666
0.0TrpMet: 0.0 ± 0.0
1.684TrpAsn: 1.684 ± 0.656
0.842TrpPro: 0.842 ± 0.444
0.421TrpGln: 0.421 ± 0.222
0.421TrpArg: 0.421 ± 0.945
0.421TrpSer: 0.421 ± 0.913
1.263TrpThr: 1.263 ± 0.82
0.842TrpVal: 0.842 ± 0.444
0.842TrpTrp: 0.842 ± 0.555
0.842TrpTyr: 0.842 ± 1.279
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.368TyrAla: 3.368 ± 0.917
0.842TyrCys: 0.842 ± 0.952
0.421TyrAsp: 0.421 ± 0.222
0.0TyrGlu: 0.0 ± 0.0
1.263TyrPhe: 1.263 ± 0.606
1.263TyrGly: 1.263 ± 0.666
0.0TyrHis: 0.0 ± 0.0
1.684TyrIle: 1.684 ± 0.606
1.684TyrLys: 1.684 ± 0.656
2.947TyrLeu: 2.947 ± 1.231
1.263TyrMet: 1.263 ± 0.641
0.842TyrAsn: 0.842 ± 0.444
1.263TyrPro: 1.263 ± 0.507
0.421TyrGln: 0.421 ± 0.222
0.842TyrArg: 0.842 ± 1.225
2.105TyrSer: 2.105 ± 0.705
2.947TyrThr: 2.947 ± 1.135
0.842TyrVal: 0.842 ± 0.776
0.0TyrTrp: 0.0 ± 0.0
0.842TyrTyr: 0.842 ± 0.444
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2376 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski