Amino acid dipepetide frequency for Apolygus lucorum (Plant bug) (Lygocoris lucorum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.394AlaAla: 5.394 ± 0.041	1.105AlaCys: 1.105 ± 0.015	3.131AlaAsp: 3.131 ± 0.025	4.063AlaGlu: 4.063 ± 0.029	2.224AlaPhe: 2.224 ± 0.017	3.627AlaGly: 3.627 ± 0.031	1.345AlaHis: 1.345 ± 0.015	3.186AlaIle: 3.186 ± 0.023	3.772AlaLys: 3.772 ± 0.027	5.8AlaLeu: 5.8 ± 0.04	1.533AlaMet: 1.533 ± 0.014	2.433AlaAsn: 2.433 ± 0.019	3.491AlaPro: 3.491 ± 0.036	2.369AlaGln: 2.369 ± 0.025	3.181AlaArg: 3.181 ± 0.025	5.015AlaSer: 5.015 ± 0.03	3.707AlaThr: 3.707 ± 0.026	4.553AlaVal: 4.553 ± 0.03	0.635AlaTrp: 0.635 ± 0.009	1.651AlaTyr: 1.651 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	1.016CysAla: 1.016 ± 0.013	0.481CysCys: 0.481 ± 0.013	1.191CysAsp: 1.191 ± 0.02	1.138CysGlu: 1.138 ± 0.017	0.753CysPhe: 0.753 ± 0.011	1.418CysGly: 1.418 ± 0.023	0.508CysHis: 0.508 ± 0.008	0.938CysIle: 0.938 ± 0.012	1.11CysLys: 1.11 ± 0.017	1.777CysLeu: 1.777 ± 0.02	0.407CysMet: 0.407 ± 0.007	0.853CysAsn: 0.853 ± 0.013	1.099CysPro: 1.099 ± 0.018	0.752CysGln: 0.752 ± 0.013	1.099CysArg: 1.099 ± 0.014	1.738CysSer: 1.738 ± 0.02	1.015CysThr: 1.015 ± 0.016	1.146CysVal: 1.146 ± 0.016	0.263CysTrp: 0.263 ± 0.006	0.592CysTyr: 0.592 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	3.087AspAla: 3.087 ± 0.022	1.04AspCys: 1.04 ± 0.015	4.064AspAsp: 4.064 ± 0.109	4.411AspGlu: 4.411 ± 0.034	2.3AspPhe: 2.3 ± 0.02	3.283AspGly: 3.283 ± 0.026	1.206AspHis: 1.206 ± 0.015	2.985AspIle: 2.985 ± 0.02	3.174AspLys: 3.174 ± 0.03	5.048AspLeu: 5.048 ± 0.031	1.259AspMet: 1.259 ± 0.014	2.249AspAsn: 2.249 ± 0.026	2.904AspPro: 2.904 ± 0.027	1.878AspGln: 1.878 ± 0.018	2.769AspArg: 2.769 ± 0.023	4.557AspSer: 4.557 ± 0.037	2.633AspThr: 2.633 ± 0.024	3.868AspVal: 3.868 ± 0.029	0.688AspTrp: 0.688 ± 0.01	1.745AspTyr: 1.745 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	4.258GluAla: 4.258 ± 0.027	1.147GluCys: 1.147 ± 0.018	4.473GluAsp: 4.473 ± 0.035	6.829GluGlu: 6.829 ± 0.109	2.248GluPhe: 2.248 ± 0.022	3.608GluGly: 3.608 ± 0.03	1.409GluHis: 1.409 ± 0.015	3.635GluIle: 3.635 ± 0.026	4.972GluLys: 4.972 ± 0.04	5.747GluLeu: 5.747 ± 0.038	1.763GluMet: 1.763 ± 0.017	3.202GluAsn: 3.202 ± 0.025	3.095GluPro: 3.095 ± 0.03	2.388GluGln: 2.388 ± 0.024	3.751GluArg: 3.751 ± 0.032	4.861GluSer: 4.861 ± 0.04	3.725GluThr: 3.725 ± 0.03	4.443GluVal: 4.443 ± 0.03	0.769GluTrp: 0.769 ± 0.013	1.787GluTyr: 1.787 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	2.116PheAla: 2.116 ± 0.017	0.816PheCys: 0.816 ± 0.011	2.059PheAsp: 2.059 ± 0.019	2.198PheGlu: 2.198 ± 0.022	1.586PhePhe: 1.586 ± 0.019	2.352PheGly: 2.352 ± 0.022	0.984PheHis: 0.984 ± 0.012	2.057PheIle: 2.057 ± 0.02	2.259PheLys: 2.259 ± 0.02	3.639PheLeu: 3.639 ± 0.027	0.868PheMet: 0.868 ± 0.011	1.764PheAsn: 1.764 ± 0.017	1.832PhePro: 1.832 ± 0.017	1.4PheGln: 1.4 ± 0.013	1.931PheArg: 1.931 ± 0.018	3.108PheSer: 3.108 ± 0.022	2.196PheThr: 2.196 ± 0.02	2.474PheVal: 2.474 ± 0.019	0.492PheTrp: 0.492 ± 0.008	1.284PheTyr: 1.284 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	3.56GlyAla: 3.56 ± 0.033	1.1GlyCys: 1.1 ± 0.017	3.226GlyAsp: 3.226 ± 0.024	3.549GlyGlu: 3.549 ± 0.033	2.321GlyPhe: 2.321 ± 0.021	5.009GlyGly: 5.009 ± 0.087	1.454GlyHis: 1.454 ± 0.018	2.995GlyIle: 2.995 ± 0.024	3.703GlyLys: 3.703 ± 0.027	4.767GlyLeu: 4.767 ± 0.037	1.339GlyMet: 1.339 ± 0.016	2.603GlyAsn: 2.603 ± 0.023	2.807GlyPro: 2.807 ± 0.046	2.052GlyGln: 2.052 ± 0.024	3.305GlyArg: 3.305 ± 0.026	5.166GlySer: 5.166 ± 0.045	3.336GlyThr: 3.336 ± 0.027	3.923GlyVal: 3.923 ± 0.041	0.782GlyTrp: 0.782 ± 0.013	1.924GlyTyr: 1.924 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.192HisAla: 1.192 ± 0.013	0.555HisCys: 0.555 ± 0.01	1.15HisAsp: 1.15 ± 0.012	1.326HisGlu: 1.326 ± 0.013	1.064HisPhe: 1.064 ± 0.012	1.347HisGly: 1.347 ± 0.018	0.983HisHis: 0.983 ± 0.017	1.254HisIle: 1.254 ± 0.013	1.325HisLys: 1.325 ± 0.013	2.385HisLeu: 2.385 ± 0.021	0.578HisMet: 0.578 ± 0.01	1.064HisAsn: 1.064 ± 0.013	1.459HisPro: 1.459 ± 0.018	1.184HisGln: 1.184 ± 0.017	1.373HisArg: 1.373 ± 0.014	2.023HisSer: 2.023 ± 0.021	1.19HisThr: 1.19 ± 0.015	1.446HisVal: 1.446 ± 0.014	0.287HisTrp: 0.287 ± 0.007	0.791HisTyr: 0.791 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.311IleAla: 3.311 ± 0.026	1.05IleCys: 1.05 ± 0.012	2.897IleAsp: 2.897 ± 0.021	3.313IleGlu: 3.313 ± 0.024	2.055IlePhe: 2.055 ± 0.02	2.774IleGly: 2.774 ± 0.023	1.299IleHis: 1.299 ± 0.014	2.806IleIle: 2.806 ± 0.024	3.229IleLys: 3.229 ± 0.025	4.734IleLeu: 4.734 ± 0.032	1.186IleMet: 1.186 ± 0.013	2.302IleAsn: 2.302 ± 0.018	3.066IlePro: 3.066 ± 0.022	2.093IleGln: 2.093 ± 0.018	2.71IleArg: 2.71 ± 0.018	4.168IleSer: 4.168 ± 0.026	3.001IleThr: 3.001 ± 0.022	3.451IleVal: 3.451 ± 0.022	0.565IleTrp: 0.565 ± 0.009	1.51IleTyr: 1.51 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	3.74LysAla: 3.74 ± 0.027	1.24LysCys: 1.24 ± 0.018	3.477LysAsp: 3.477 ± 0.03	4.95LysGlu: 4.95 ± 0.038	2.2LysPhe: 2.2 ± 0.019	3.265LysGly: 3.265 ± 0.032	1.45LysHis: 1.45 ± 0.015	3.434LysIle: 3.434 ± 0.026	5.909LysLys: 5.909 ± 0.059	5.602LysLeu: 5.602 ± 0.036	1.691LysMet: 1.691 ± 0.016	2.987LysAsn: 2.987 ± 0.021	3.505LysPro: 3.505 ± 0.041	2.381LysGln: 2.381 ± 0.019	3.966LysArg: 3.966 ± 0.024	4.986LysSer: 4.986 ± 0.056	3.779LysThr: 3.779 ± 0.034	3.858LysVal: 3.858 ± 0.03	0.784LysTrp: 0.784 ± 0.014	1.937LysTyr: 1.937 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	5.752LeuAla: 5.752 ± 0.033	1.721LeuCys: 1.721 ± 0.021	4.683LeuAsp: 4.683 ± 0.028	6.08LeuGlu: 6.08 ± 0.041	3.215LeuPhe: 3.215 ± 0.027	4.797LeuGly: 4.797 ± 0.032	2.174LeuHis: 2.174 ± 0.018	4.379LeuIle: 4.379 ± 0.027	6.173LeuLys: 6.173 ± 0.039	8.487LeuLeu: 8.487 ± 0.051	2.103LeuMet: 2.103 ± 0.015	3.933LeuAsn: 3.933 ± 0.025	5.096LeuPro: 5.096 ± 0.035	3.88LeuGln: 3.88 ± 0.026	5.227LeuArg: 5.227 ± 0.032	7.058LeuSer: 7.058 ± 0.037	5.105LeuThr: 5.105 ± 0.029	5.64LeuVal: 5.64 ± 0.043	0.981LeuTrp: 0.981 ± 0.013	2.48LeuTyr: 2.48 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.657MetAla: 1.657 ± 0.017	0.433MetCys: 0.433 ± 0.008	1.417MetAsp: 1.417 ± 0.016	1.774MetGlu: 1.774 ± 0.016	0.885MetPhe: 0.885 ± 0.012	1.31MetGly: 1.31 ± 0.017	0.429MetHis: 0.429 ± 0.008	1.178MetIle: 1.178 ± 0.012	1.786MetLys: 1.786 ± 0.016	1.85MetLeu: 1.85 ± 0.016	0.73MetMet: 0.73 ± 0.011	1.136MetAsn: 1.136 ± 0.013	1.092MetPro: 1.092 ± 0.013	0.809MetGln: 0.809 ± 0.012	1.265MetArg: 1.265 ± 0.013	1.93MetSer: 1.93 ± 0.017	1.398MetThr: 1.398 ± 0.013	1.481MetVal: 1.481 ± 0.014	0.267MetTrp: 0.267 ± 0.006	0.692MetTyr: 0.692 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.457AsnAla: 2.457 ± 0.02	0.898AsnCys: 0.898 ± 0.013	2.295AsnAsp: 2.295 ± 0.018	2.882AsnGlu: 2.882 ± 0.022	1.793AsnPhe: 1.793 ± 0.016	2.707AsnGly: 2.707 ± 0.023	1.12AsnHis: 1.12 ± 0.014	2.541AsnIle: 2.541 ± 0.019	2.737AsnLys: 2.737 ± 0.022	4.105AsnLeu: 4.105 ± 0.025	1.15AsnMet: 1.15 ± 0.015	2.324AsnAsn: 2.324 ± 0.028	2.447AsnPro: 2.447 ± 0.023	1.807AsnGln: 1.807 ± 0.016	2.285AsnArg: 2.285 ± 0.019	3.653AsnSer: 3.653 ± 0.028	2.303AsnThr: 2.303 ± 0.021	2.951AsnVal: 2.951 ± 0.021	0.527AsnTrp: 0.527 ± 0.008	1.491AsnTyr: 1.491 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	3.613ProAla: 3.613 ± 0.035	0.916ProCys: 0.916 ± 0.015	2.864ProAsp: 2.864 ± 0.021	3.741ProGlu: 3.741 ± 0.036	1.894ProPhe: 1.894 ± 0.018	3.482ProGly: 3.482 ± 0.054	1.358ProHis: 1.358 ± 0.02	2.652ProIle: 2.652 ± 0.021	3.307ProLys: 3.307 ± 0.031	4.567ProLeu: 4.567 ± 0.031	1.064ProMet: 1.064 ± 0.015	2.334ProAsn: 2.334 ± 0.023	5.736ProPro: 5.736 ± 0.074	2.503ProGln: 2.503 ± 0.028	2.96ProArg: 2.96 ± 0.029	5.404ProSer: 5.404 ± 0.043	3.655ProThr: 3.655 ± 0.038	3.819ProVal: 3.819 ± 0.031	0.613ProTrp: 0.613 ± 0.012	1.625ProTyr: 1.625 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	2.379GlnAla: 2.379 ± 0.022	0.711GlnCys: 0.711 ± 0.013	1.92GlnAsp: 1.92 ± 0.02	2.789GlnGlu: 2.789 ± 0.023	1.39GlnPhe: 1.39 ± 0.015	2.175GlnGly: 2.175 ± 0.03	1.033GlnHis: 1.033 ± 0.015	2.013GlnIle: 2.013 ± 0.016	2.412GlnLys: 2.412 ± 0.02	3.755GlnLeu: 3.755 ± 0.031	1.021GlnMet: 1.021 ± 0.012	1.821GlnAsn: 1.821 ± 0.018	2.371GlnPro: 2.371 ± 0.03	2.446GlnGln: 2.446 ± 0.047	2.304GlnArg: 2.304 ± 0.017	2.818GlnSer: 2.818 ± 0.023	2.162GlnThr: 2.162 ± 0.018	2.434GlnVal: 2.434 ± 0.016	0.453GlnTrp: 0.453 ± 0.008	1.149GlnTyr: 1.149 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	3.192ArgAla: 3.192 ± 0.027	1.099ArgCys: 1.099 ± 0.017	2.787ArgAsp: 2.787 ± 0.027	3.574ArgGlu: 3.574 ± 0.032	2.016ArgPhe: 2.016 ± 0.018	3.152ArgGly: 3.152 ± 0.028	1.453ArgHis: 1.453 ± 0.016	2.87ArgIle: 2.87 ± 0.021	4.201ArgLys: 4.201 ± 0.03	4.879ArgLeu: 4.879 ± 0.03	1.305ArgMet: 1.305 ± 0.013	2.616ArgAsn: 2.616 ± 0.021	2.983ArgPro: 2.983 ± 0.033	2.186ArgGln: 2.186 ± 0.016	4.354ArgArg: 4.354 ± 0.035	4.53ArgSer: 4.53 ± 0.037	3.026ArgThr: 3.026 ± 0.021	3.19ArgVal: 3.19 ± 0.021	0.671ArgTrp: 0.671 ± 0.009	1.571ArgTyr: 1.571 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	4.921SerAla: 4.921 ± 0.031	1.598SerCys: 1.598 ± 0.02	4.615SerAsp: 4.615 ± 0.032	5.187SerGlu: 5.187 ± 0.041	2.987SerPhe: 2.987 ± 0.023	5.181SerGly: 5.181 ± 0.044	1.915SerHis: 1.915 ± 0.019	3.963SerIle: 3.963 ± 0.024	5.091SerLys: 5.091 ± 0.045	7.224SerLeu: 7.224 ± 0.041	1.72SerMet: 1.72 ± 0.016	3.547SerAsn: 3.547 ± 0.023	5.396SerPro: 5.396 ± 0.045	3.252SerGln: 3.252 ± 0.025	4.617SerArg: 4.617 ± 0.036	9.267SerSer: 9.267 ± 0.074	5.242SerThr: 5.242 ± 0.06	5.037SerVal: 5.037 ± 0.031	0.982SerTrp: 0.982 ± 0.013	2.303SerTyr: 2.303 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	3.826ThrAla: 3.826 ± 0.027	1.159ThrCys: 1.159 ± 0.018	2.85ThrAsp: 2.85 ± 0.023	3.465ThrGlu: 3.465 ± 0.027	2.122ThrPhe: 2.122 ± 0.019	3.334ThrGly: 3.334 ± 0.032	1.242ThrHis: 1.242 ± 0.013	3.039ThrIle: 3.039 ± 0.023	3.421ThrLys: 3.421 ± 0.033	5.108ThrLeu: 5.108 ± 0.029	1.279ThrMet: 1.279 ± 0.013	2.463ThrAsn: 2.463 ± 0.02	4.095ThrPro: 4.095 ± 0.039	2.104ThrGln: 2.104 ± 0.025	2.86ThrArg: 2.86 ± 0.025	5.31ThrSer: 5.31 ± 0.035	4.14ThrThr: 4.14 ± 0.072	3.903ThrVal: 3.903 ± 0.029	0.627ThrTrp: 0.627 ± 0.009	1.617ThrTyr: 1.617 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.472ValAla: 4.472 ± 0.031	1.317ValCys: 1.317 ± 0.017	3.664ValAsp: 3.664 ± 0.024	4.384ValGlu: 4.384 ± 0.031	2.501ValPhe: 2.501 ± 0.022	3.577ValGly: 3.577 ± 0.027	1.518ValHis: 1.518 ± 0.013	3.449ValIle: 3.449 ± 0.024	4.0ValLys: 4.0 ± 0.027	5.703ValLeu: 5.703 ± 0.033	1.508ValMet: 1.508 ± 0.015	2.811ValAsn: 2.811 ± 0.021	3.635ValPro: 3.635 ± 0.027	2.443ValGln: 2.443 ± 0.019	3.323ValArg: 3.323 ± 0.027	5.174ValSer: 5.174 ± 0.035	4.048ValThr: 4.048 ± 0.033	4.754ValVal: 4.754 ± 0.038	0.729ValTrp: 0.729 ± 0.009	1.812ValTyr: 1.812 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.652TrpAla: 0.652 ± 0.01	0.228TrpCys: 0.228 ± 0.005	0.676TrpAsp: 0.676 ± 0.01	0.738TrpGlu: 0.738 ± 0.011	0.518TrpPhe: 0.518 ± 0.009	0.661TrpGly: 0.661 ± 0.011	0.242TrpHis: 0.242 ± 0.005	0.665TrpIle: 0.665 ± 0.009	0.847TrpLys: 0.847 ± 0.011	1.046TrpLeu: 1.046 ± 0.014	0.348TrpMet: 0.348 ± 0.006	0.591TrpAsn: 0.591 ± 0.008	0.461TrpPro: 0.461 ± 0.008	0.404TrpGln: 0.404 ± 0.009	0.722TrpArg: 0.722 ± 0.009	0.92TrpSer: 0.92 ± 0.015	0.698TrpThr: 0.698 ± 0.01	0.695TrpVal: 0.695 ± 0.01	0.187TrpTrp: 0.187 ± 0.005	0.392TrpTyr: 0.392 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.62TyrAla: 1.62 ± 0.017	0.679TyrCys: 0.679 ± 0.01	1.708TyrAsp: 1.708 ± 0.017	1.718TyrGlu: 1.718 ± 0.016	1.344TyrPhe: 1.344 ± 0.015	1.863TyrGly: 1.863 ± 0.022	0.853TyrHis: 0.853 ± 0.011	1.481TyrIle: 1.481 ± 0.017	1.715TyrLys: 1.715 ± 0.013	2.741TyrLeu: 2.741 ± 0.021	0.668TyrMet: 0.668 ± 0.009	1.441TyrAsn: 1.441 ± 0.015	1.536TyrPro: 1.536 ± 0.023	1.226TyrGln: 1.226 ± 0.014	1.651TyrArg: 1.651 ± 0.018	2.359TyrSer: 2.359 ± 0.019	1.604TyrThr: 1.604 ± 0.016	1.76TyrVal: 1.76 ± 0.015	0.388TyrTrp: 0.388 ± 0.007	1.113TyrTyr: 1.113 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 21887 proteins (9312152 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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