Amino acid dipepetide frequency for Apis mellifera associated microvirus 27

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.753AlaAla: 12.753 ± 7.249
0.0AlaCys: 0.0 ± 0.0
4.501AlaAsp: 4.501 ± 1.418
8.252AlaGlu: 8.252 ± 2.758
2.251AlaPhe: 2.251 ± 1.317
6.752AlaGly: 6.752 ± 3.993
0.0AlaHis: 0.0 ± 0.0
3.751AlaIle: 3.751 ± 0.826
4.501AlaLys: 4.501 ± 1.987
4.501AlaLeu: 4.501 ± 3.052
0.0AlaMet: 0.0 ± 0.0
3.751AlaAsn: 3.751 ± 2.647
4.501AlaPro: 4.501 ± 1.386
2.251AlaGln: 2.251 ± 0.89
6.752AlaArg: 6.752 ± 1.454
3.751AlaSer: 3.751 ± 2.647
4.501AlaThr: 4.501 ± 1.931
5.251AlaVal: 5.251 ± 2.086
0.0AlaTrp: 0.0 ± 0.0
1.5AlaTyr: 1.5 ± 0.629
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.5CysAsp: 1.5 ± 1.024
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.75CysHis: 0.75 ± 0.641
0.75CysIle: 0.75 ± 0.641
0.0CysLys: 0.0 ± 0.0
0.75CysLeu: 0.75 ± 0.641
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.75CysPro: 0.75 ± 0.641
0.0CysGln: 0.0 ± 0.0
1.5CysArg: 1.5 ± 1.283
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.75CysVal: 0.75 ± 0.641
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.5AspAla: 1.5 ± 1.017
0.0AspCys: 0.0 ± 0.0
1.5AspAsp: 1.5 ± 1.209
2.251AspGlu: 2.251 ± 1.828
6.752AspPhe: 6.752 ± 1.796
0.0AspGly: 0.0 ± 0.0
0.0AspHis: 0.0 ± 0.0
1.5AspIle: 1.5 ± 1.197
1.5AspLys: 1.5 ± 0.543
6.002AspLeu: 6.002 ± 1.227
0.0AspMet: 0.0 ± 0.0
1.5AspAsn: 1.5 ± 1.017
6.002AspPro: 6.002 ± 2.459
2.251AspGln: 2.251 ± 1.074
0.75AspArg: 0.75 ± 0.509
3.001AspSer: 3.001 ± 2.034
4.501AspThr: 4.501 ± 2.166
4.501AspVal: 4.501 ± 1.418
0.75AspTrp: 0.75 ± 0.641
4.501AspTyr: 4.501 ± 2.237
0.0AspXaa: 0.0 ± 0.0
Glu
6.002GluAla: 6.002 ± 3.563
1.5GluCys: 1.5 ± 1.283
0.75GluAsp: 0.75 ± 0.94
5.251GluGlu: 5.251 ± 1.399
2.251GluPhe: 2.251 ± 0.89
0.0GluGly: 0.0 ± 0.0
3.001GluHis: 3.001 ± 1.241
6.752GluIle: 6.752 ± 1.615
5.251GluLys: 5.251 ± 2.247
5.251GluLeu: 5.251 ± 2.247
2.251GluMet: 2.251 ± 1.189
3.001GluAsn: 3.001 ± 1.161
1.5GluPro: 1.5 ± 1.209
4.501GluGln: 4.501 ± 1.369
3.751GluArg: 3.751 ± 1.654
3.001GluSer: 3.001 ± 1.619
4.501GluThr: 4.501 ± 1.877
0.75GluVal: 0.75 ± 0.885
0.0GluTrp: 0.0 ± 0.0
1.5GluTyr: 1.5 ± 0.543
0.0GluXaa: 0.0 ± 0.0
Phe
3.001PheAla: 3.001 ± 0.92
0.0PheCys: 0.0 ± 0.0
3.751PheAsp: 3.751 ± 2.157
2.251PheGlu: 2.251 ± 0.74
3.001PhePhe: 3.001 ± 1.713
6.002PheGly: 6.002 ± 2.697
1.5PheHis: 1.5 ± 1.045
1.5PheIle: 1.5 ± 1.017
5.251PheLys: 5.251 ± 2.659
6.002PheLeu: 6.002 ± 1.884
1.5PheMet: 1.5 ± 0.599
3.001PheAsn: 3.001 ± 1.086
0.75PhePro: 0.75 ± 0.509
4.501PheGln: 4.501 ± 1.128
3.001PheArg: 3.001 ± 2.034
1.5PheSer: 1.5 ± 1.017
2.251PheThr: 2.251 ± 0.834
1.5PheVal: 1.5 ± 1.017
1.5PheTrp: 1.5 ± 1.017
0.75PheTyr: 0.75 ± 0.509
0.0PheXaa: 0.0 ± 0.0
Gly
5.251GlyAla: 5.251 ± 2.458
0.0GlyCys: 0.0 ± 0.0
5.251GlyAsp: 5.251 ± 1.828
3.001GlyGlu: 3.001 ± 1.092
3.751GlyPhe: 3.751 ± 1.577
5.251GlyGly: 5.251 ± 0.898
0.0GlyHis: 0.0 ± 0.0
3.001GlyIle: 3.001 ± 0.83
4.501GlyLys: 4.501 ± 2.081
3.751GlyLeu: 3.751 ± 1.153
0.75GlyMet: 0.75 ± 0.719
3.751GlyAsn: 3.751 ± 1.789
2.251GlyPro: 2.251 ± 0.89
3.751GlyGln: 3.751 ± 1.366
2.251GlyArg: 2.251 ± 0.74
4.501GlySer: 4.501 ± 1.386
6.752GlyThr: 6.752 ± 2.453
0.75GlyVal: 0.75 ± 0.885
1.5GlyTrp: 1.5 ± 1.017
3.751GlyTyr: 3.751 ± 2.109
0.0GlyXaa: 0.0 ± 0.0
His
1.5HisAla: 1.5 ± 0.895
0.0HisCys: 0.0 ± 0.0
1.5HisAsp: 1.5 ± 0.543
0.75HisGlu: 0.75 ± 0.641
0.75HisPhe: 0.75 ± 0.509
3.001HisGly: 3.001 ± 1.241
0.0HisHis: 0.0 ± 0.0
1.5HisIle: 1.5 ± 1.024
3.001HisLys: 3.001 ± 2.565
2.251HisLeu: 2.251 ± 1.526
0.75HisMet: 0.75 ± 0.719
0.75HisAsn: 0.75 ± 0.94
3.751HisPro: 3.751 ± 1.921
0.0HisGln: 0.0 ± 0.0
0.75HisArg: 0.75 ± 0.641
0.75HisSer: 0.75 ± 0.509
0.75HisThr: 0.75 ± 0.641
0.0HisVal: 0.0 ± 0.0
0.75HisTrp: 0.75 ± 0.641
0.75HisTyr: 0.75 ± 0.641
0.0HisXaa: 0.0 ± 0.0
Ile
2.251IleAla: 2.251 ± 0.552
0.75IleCys: 0.75 ± 0.94
2.251IleAsp: 2.251 ± 0.834
3.001IleGlu: 3.001 ± 1.143
3.001IlePhe: 3.001 ± 1.994
2.251IleGly: 2.251 ± 0.552
0.0IleHis: 0.0 ± 0.0
3.001IleIle: 3.001 ± 1.143
2.251IleLys: 2.251 ± 1.271
3.001IleLeu: 3.001 ± 1.161
0.75IleMet: 0.75 ± 0.885
5.251IleAsn: 5.251 ± 0.77
3.751IlePro: 3.751 ± 0.93
4.501IleGln: 4.501 ± 0.624
3.001IleArg: 3.001 ± 1.086
1.5IleSer: 1.5 ± 0.543
3.001IleThr: 3.001 ± 1.563
2.251IleVal: 2.251 ± 1.881
0.0IleTrp: 0.0 ± 0.0
0.75IleTyr: 0.75 ± 0.509
0.0IleXaa: 0.0 ± 0.0
Lys
7.502LysAla: 7.502 ± 3.117
0.75LysCys: 0.75 ± 0.641
2.251LysAsp: 2.251 ± 0.939
2.251LysGlu: 2.251 ± 1.271
3.001LysPhe: 3.001 ± 1.271
2.251LysGly: 2.251 ± 0.89
3.001LysHis: 3.001 ± 0.571
5.251LysIle: 5.251 ± 2.251
7.502LysLys: 7.502 ± 4.075
6.752LysLeu: 6.752 ± 4.471
3.001LysMet: 3.001 ± 1.448
6.752LysAsn: 6.752 ± 4.247
1.5LysPro: 1.5 ± 0.895
3.001LysGln: 3.001 ± 1.705
3.001LysArg: 3.001 ± 1.684
6.752LysSer: 6.752 ± 1.952
6.002LysThr: 6.002 ± 2.185
0.75LysVal: 0.75 ± 0.719
0.75LysTrp: 0.75 ± 0.509
0.75LysTyr: 0.75 ± 0.719
0.0LysXaa: 0.0 ± 0.0
Leu
4.501LeuAla: 4.501 ± 1.639
0.75LeuCys: 0.75 ± 0.509
2.251LeuAsp: 2.251 ± 0.834
4.501LeuGlu: 4.501 ± 1.072
2.251LeuPhe: 2.251 ± 0.834
6.752LeuGly: 6.752 ± 1.08
3.001LeuHis: 3.001 ± 1.241
0.75LeuIle: 0.75 ± 0.509
7.502LeuLys: 7.502 ± 3.17
3.001LeuLeu: 3.001 ± 0.92
3.751LeuMet: 3.751 ± 1.489
6.752LeuAsn: 6.752 ± 0.656
6.752LeuPro: 6.752 ± 1.557
4.501LeuGln: 4.501 ± 0.92
3.001LeuArg: 3.001 ± 1.538
4.501LeuSer: 4.501 ± 1.956
6.002LeuThr: 6.002 ± 3.367
4.501LeuVal: 4.501 ± 2.258
1.5LeuTrp: 1.5 ± 0.543
3.001LeuTyr: 3.001 ± 1.213
0.0LeuXaa: 0.0 ± 0.0
Met
1.5MetAla: 1.5 ± 1.197
0.0MetCys: 0.0 ± 0.0
0.75MetAsp: 0.75 ± 0.509
2.251MetGlu: 2.251 ± 2.156
0.75MetPhe: 0.75 ± 0.94
1.5MetGly: 1.5 ± 1.017
0.0MetHis: 0.0 ± 0.0
0.75MetIle: 0.75 ± 0.719
2.251MetLys: 2.251 ± 1.271
1.5MetLeu: 1.5 ± 0.543
0.0MetMet: 0.0 ± 0.0
0.75MetAsn: 0.75 ± 0.641
1.5MetPro: 1.5 ± 1.046
1.5MetGln: 1.5 ± 0.895
0.75MetArg: 0.75 ± 0.509
5.251MetSer: 5.251 ± 2.109
0.0MetThr: 0.0 ± 0.0
1.5MetVal: 1.5 ± 0.543
0.0MetTrp: 0.0 ± 0.0
2.251MetTyr: 2.251 ± 1.095
0.0MetXaa: 0.0 ± 0.0
Asn
5.251AsnAla: 5.251 ± 1.351
0.75AsnCys: 0.75 ± 0.641
4.501AsnAsp: 4.501 ± 3.656
3.001AsnGlu: 3.001 ± 1.545
0.75AsnPhe: 0.75 ± 0.885
3.751AsnGly: 3.751 ± 1.625
1.5AsnHis: 1.5 ± 1.045
3.001AsnIle: 3.001 ± 1.018
3.751AsnLys: 3.751 ± 0.826
6.002AsnLeu: 6.002 ± 1.663
0.75AsnMet: 0.75 ± 0.885
2.251AsnAsn: 2.251 ± 0.978
4.501AsnPro: 4.501 ± 2.166
2.251AsnGln: 2.251 ± 1.252
2.251AsnArg: 2.251 ± 1.526
0.75AsnSer: 0.75 ± 0.719
3.751AsnThr: 3.751 ± 1.153
1.5AsnVal: 1.5 ± 1.017
0.0AsnTrp: 0.0 ± 0.0
3.001AsnTyr: 3.001 ± 1.684
0.0AsnXaa: 0.0 ± 0.0
Pro
3.001ProAla: 3.001 ± 2.034
0.75ProCys: 0.75 ± 0.641
3.751ProAsp: 3.751 ± 0.949
6.002ProGlu: 6.002 ± 3.308
3.751ProPhe: 3.751 ± 2.157
5.251ProGly: 5.251 ± 0.519
2.251ProHis: 2.251 ± 1.074
1.5ProIle: 1.5 ± 0.782
3.751ProLys: 3.751 ± 1.16
3.001ProLeu: 3.001 ± 0.92
2.251ProMet: 2.251 ± 0.878
3.001ProAsn: 3.001 ± 1.143
1.5ProPro: 1.5 ± 1.045
2.251ProGln: 2.251 ± 1.526
3.751ProArg: 3.751 ± 1.577
3.751ProSer: 3.751 ± 1.331
3.751ProThr: 3.751 ± 1.491
7.502ProVal: 7.502 ± 1.936
0.0ProTrp: 0.0 ± 0.0
1.5ProTyr: 1.5 ± 1.017
0.0ProXaa: 0.0 ± 0.0
Gln
4.501GlnAla: 4.501 ± 1.639
0.75GlnCys: 0.75 ± 0.641
2.251GlnAsp: 2.251 ± 0.834
4.501GlnGlu: 4.501 ± 1.007
1.5GlnPhe: 1.5 ± 1.017
1.5GlnGly: 1.5 ± 1.017
1.5GlnHis: 1.5 ± 1.017
1.5GlnIle: 1.5 ± 0.895
5.251GlnLys: 5.251 ± 2.705
4.501GlnLeu: 4.501 ± 0.732
2.251GlnMet: 2.251 ± 2.156
3.001GlnAsn: 3.001 ± 0.946
2.251GlnPro: 2.251 ± 1.59
5.251GlnGln: 5.251 ± 1.173
1.5GlnArg: 1.5 ± 0.629
3.751GlnSer: 3.751 ± 2.157
2.251GlnThr: 2.251 ± 0.89
2.251GlnVal: 2.251 ± 0.834
0.75GlnTrp: 0.75 ± 0.509
0.75GlnTyr: 0.75 ± 0.641
0.0GlnXaa: 0.0 ± 0.0
Arg
2.251ArgAla: 2.251 ± 0.552
0.0ArgCys: 0.0 ± 0.0
3.751ArgAsp: 3.751 ± 0.908
4.501ArgGlu: 4.501 ± 1.539
3.001ArgPhe: 3.001 ± 1.563
3.001ArgGly: 3.001 ± 1.349
0.75ArgHis: 0.75 ± 0.641
1.5ArgIle: 1.5 ± 0.629
1.5ArgLys: 1.5 ± 1.046
7.502ArgLeu: 7.502 ± 1.115
0.75ArgMet: 0.75 ± 0.509
0.75ArgAsn: 0.75 ± 0.641
3.001ArgPro: 3.001 ± 1.271
1.5ArgGln: 1.5 ± 0.543
0.75ArgArg: 0.75 ± 0.509
2.251ArgSer: 2.251 ± 1.526
5.251ArgThr: 5.251 ± 1.815
0.75ArgVal: 0.75 ± 0.509
0.75ArgTrp: 0.75 ± 0.641
5.251ArgTyr: 5.251 ± 2.089
0.0ArgXaa: 0.0 ± 0.0
Ser
7.502SerAla: 7.502 ± 2.873
0.75SerCys: 0.75 ± 0.641
2.251SerAsp: 2.251 ± 0.939
3.751SerGlu: 3.751 ± 1.771
4.501SerPhe: 4.501 ± 3.052
2.251SerGly: 2.251 ± 0.89
1.5SerHis: 1.5 ± 0.629
4.501SerIle: 4.501 ± 1.797
4.501SerLys: 4.501 ± 0.732
3.751SerLeu: 3.751 ± 0.93
1.5SerMet: 1.5 ± 0.782
3.001SerAsn: 3.001 ± 1.349
3.001SerPro: 3.001 ± 1.143
2.251SerGln: 2.251 ± 0.89
2.251SerArg: 2.251 ± 0.834
0.75SerSer: 0.75 ± 0.509
6.752SerThr: 6.752 ± 2.453
2.251SerVal: 2.251 ± 0.552
0.0SerTrp: 0.0 ± 0.0
2.251SerTyr: 2.251 ± 1.271
0.0SerXaa: 0.0 ± 0.0
Thr
6.752ThrAla: 6.752 ± 3.747
0.0ThrCys: 0.0 ± 0.0
1.5ThrAsp: 1.5 ± 0.543
3.001ThrGlu: 3.001 ± 1.538
3.751ThrPhe: 3.751 ± 0.53
5.251ThrGly: 5.251 ± 1.776
1.5ThrHis: 1.5 ± 1.045
5.251ThrIle: 5.251 ± 1.282
3.751ThrLys: 3.751 ± 2.109
5.251ThrLeu: 5.251 ± 1.376
0.75ThrMet: 0.75 ± 0.719
3.001ThrAsn: 3.001 ± 1.259
6.752ThrPro: 6.752 ± 2.453
1.5ThrGln: 1.5 ± 0.782
5.251ThrArg: 5.251 ± 1.399
5.251ThrSer: 5.251 ± 1.007
3.001ThrThr: 3.001 ± 1.213
3.001ThrVal: 3.001 ± 1.306
0.0ThrTrp: 0.0 ± 0.0
4.501ThrTyr: 4.501 ± 1.099
0.0ThrXaa: 0.0 ± 0.0
Val
2.251ValAla: 2.251 ± 1.491
0.0ValCys: 0.0 ± 0.0
2.251ValAsp: 2.251 ± 0.834
2.251ValGlu: 2.251 ± 1.59
3.001ValPhe: 3.001 ± 1.271
4.501ValGly: 4.501 ± 1.668
1.5ValHis: 1.5 ± 1.283
0.0ValIle: 0.0 ± 0.0
3.751ValLys: 3.751 ± 1.16
3.001ValLeu: 3.001 ± 1.271
0.75ValMet: 0.75 ± 0.719
1.5ValAsn: 1.5 ± 1.045
6.002ValPro: 6.002 ± 2.018
1.5ValGln: 1.5 ± 0.782
2.251ValArg: 2.251 ± 0.89
3.751ValSer: 3.751 ± 1.696
4.501ValThr: 4.501 ± 1.452
2.251ValVal: 2.251 ± 0.978
1.5ValTrp: 1.5 ± 0.543
0.75ValTyr: 0.75 ± 0.509
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.5TrpPhe: 1.5 ± 1.017
1.5TrpGly: 1.5 ± 0.543
1.5TrpHis: 1.5 ± 0.543
0.75TrpIle: 0.75 ± 0.641
0.0TrpLys: 0.0 ± 0.0
1.5TrpLeu: 1.5 ± 1.283
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.75TrpPro: 0.75 ± 0.509
1.5TrpGln: 1.5 ± 1.017
0.0TrpArg: 0.0 ± 0.0
0.75TrpSer: 0.75 ± 0.509
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.251TyrAla: 2.251 ± 1.074
0.0TyrCys: 0.0 ± 0.0
2.251TyrAsp: 2.251 ± 1.095
0.0TyrGlu: 0.0 ± 0.0
3.001TyrPhe: 3.001 ± 2.034
3.001TyrGly: 3.001 ± 1.018
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
3.001TyrLys: 3.001 ± 1.259
2.251TyrLeu: 2.251 ± 0.94
2.251TyrMet: 2.251 ± 0.834
1.5TyrAsn: 1.5 ± 0.629
2.251TyrPro: 2.251 ± 0.834
3.001TyrGln: 3.001 ± 1.018
2.251TyrArg: 2.251 ± 0.978
3.751TyrSer: 3.751 ± 0.901
1.5TyrThr: 1.5 ± 0.782
5.251TyrVal: 5.251 ± 2.034
0.0TyrTrp: 0.0 ± 0.0
2.251TyrTyr: 2.251 ± 1.218
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1334 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski