Amino acid dipepetide frequency for Parasulfuritortus cantonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.082AlaAla: 18.082 ± 0.221	1.452AlaCys: 1.452 ± 0.04	7.534AlaAsp: 7.534 ± 0.11	8.425AlaGlu: 8.425 ± 0.118	3.854AlaPhe: 3.854 ± 0.065	12.566AlaGly: 12.566 ± 0.168	2.434AlaHis: 2.434 ± 0.054	5.312AlaIle: 5.312 ± 0.078	4.103AlaLys: 4.103 ± 0.092	13.553AlaLeu: 13.553 ± 0.159	3.589AlaMet: 3.589 ± 0.064	2.949AlaAsn: 2.949 ± 0.055	5.702AlaPro: 5.702 ± 0.109	4.039AlaGln: 4.039 ± 0.068	9.697AlaArg: 9.697 ± 0.145	5.757AlaSer: 5.757 ± 0.086	5.428AlaThr: 5.428 ± 0.095	9.221AlaVal: 9.221 ± 0.102	2.167AlaTrp: 2.167 ± 0.058	2.901AlaTyr: 2.901 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	1.155CysAla: 1.155 ± 0.045	0.158CysCys: 0.158 ± 0.014	0.499CysAsp: 0.499 ± 0.023	0.493CysGlu: 0.493 ± 0.024	0.275CysPhe: 0.275 ± 0.016	0.988CysGly: 0.988 ± 0.034	0.383CysHis: 0.383 ± 0.029	0.359CysIle: 0.359 ± 0.019	0.25CysLys: 0.25 ± 0.018	1.008CysLeu: 1.008 ± 0.033	0.186CysMet: 0.186 ± 0.014	0.259CysAsn: 0.259 ± 0.017	0.677CysPro: 0.677 ± 0.029	0.345CysGln: 0.345 ± 0.017	0.751CysArg: 0.751 ± 0.033	0.53CysSer: 0.53 ± 0.025	0.471CysThr: 0.471 ± 0.023	0.653CysVal: 0.653 ± 0.03	0.106CysTrp: 0.106 ± 0.011	0.243CysTyr: 0.243 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.864AspAla: 6.864 ± 0.105	0.595AspCys: 0.595 ± 0.027	3.302AspAsp: 3.302 ± 0.08	3.365AspGlu: 3.365 ± 0.068	2.237AspPhe: 2.237 ± 0.047	5.245AspGly: 5.245 ± 0.103	1.198AspHis: 1.198 ± 0.037	2.759AspIle: 2.759 ± 0.056	2.023AspLys: 2.023 ± 0.049	6.576AspLeu: 6.576 ± 0.092	1.357AspMet: 1.357 ± 0.035	1.499AspAsn: 1.499 ± 0.046	3.344AspPro: 3.344 ± 0.065	1.802AspGln: 1.802 ± 0.046	4.012AspArg: 4.012 ± 0.072	2.491AspSer: 2.491 ± 0.072	2.658AspThr: 2.658 ± 0.071	3.845AspVal: 3.845 ± 0.081	1.106AspTrp: 1.106 ± 0.033	1.86AspTyr: 1.86 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	7.968GluAla: 7.968 ± 0.131	0.456GluCys: 0.456 ± 0.024	2.66GluAsp: 2.66 ± 0.062	2.981GluGlu: 2.981 ± 0.064	1.954GluPhe: 1.954 ± 0.044	3.667GluGly: 3.667 ± 0.068	1.514GluHis: 1.514 ± 0.044	2.931GluIle: 2.931 ± 0.059	1.834GluLys: 1.834 ± 0.061	6.424GluLeu: 6.424 ± 0.093	1.354GluMet: 1.354 ± 0.037	1.444GluAsn: 1.444 ± 0.05	2.608GluPro: 2.608 ± 0.052	2.335GluGln: 2.335 ± 0.054	5.002GluArg: 5.002 ± 0.082	2.497GluSer: 2.497 ± 0.056	2.918GluThr: 2.918 ± 0.058	4.472GluVal: 4.472 ± 0.067	0.739GluTrp: 0.739 ± 0.028	1.363GluTyr: 1.363 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.949PheAla: 3.949 ± 0.072	0.36PheCys: 0.36 ± 0.018	2.348PheAsp: 2.348 ± 0.051	1.97PheGlu: 1.97 ± 0.049	1.28PhePhe: 1.28 ± 0.045	3.134PheGly: 3.134 ± 0.066	0.785PheHis: 0.785 ± 0.031	1.365PheIle: 1.365 ± 0.036	1.103PheLys: 1.103 ± 0.034	3.509PheLeu: 3.509 ± 0.069	0.844PheMet: 0.844 ± 0.029	1.064PheAsn: 1.064 ± 0.036	1.58PhePro: 1.58 ± 0.041	1.054PheGln: 1.054 ± 0.033	2.191PheArg: 2.191 ± 0.049	1.89PheSer: 1.89 ± 0.047	1.705PheThr: 1.705 ± 0.047	2.581PheVal: 2.581 ± 0.05	0.512PheTrp: 0.512 ± 0.027	0.949PheTyr: 0.949 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	8.552GlyAla: 8.552 ± 0.119	1.037GlyCys: 1.037 ± 0.037	4.662GlyAsp: 4.662 ± 0.091	4.698GlyGlu: 4.698 ± 0.072	3.166GlyPhe: 3.166 ± 0.058	6.805GlyGly: 6.805 ± 0.102	2.343GlyHis: 2.343 ± 0.055	4.099GlyIle: 4.099 ± 0.069	3.418GlyLys: 3.418 ± 0.074	9.869GlyLeu: 9.869 ± 0.125	2.326GlyMet: 2.326 ± 0.053	2.347GlyAsn: 2.347 ± 0.058	3.074GlyPro: 3.074 ± 0.059	3.314GlyGln: 3.314 ± 0.068	6.917GlyArg: 6.917 ± 0.115	4.012GlySer: 4.012 ± 0.081	3.818GlyThr: 3.818 ± 0.102	6.187GlyVal: 6.187 ± 0.1	1.313GlyTrp: 1.313 ± 0.04	2.678GlyTyr: 2.678 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.71HisAla: 2.71 ± 0.062	0.242HisCys: 0.242 ± 0.014	1.408HisAsp: 1.408 ± 0.043	1.194HisGlu: 1.194 ± 0.04	0.972HisPhe: 0.972 ± 0.034	2.188HisGly: 2.188 ± 0.055	0.69HisHis: 0.69 ± 0.031	1.018HisIle: 1.018 ± 0.032	0.634HisLys: 0.634 ± 0.027	2.59HisLeu: 2.59 ± 0.051	0.481HisMet: 0.481 ± 0.022	0.535HisAsn: 0.535 ± 0.027	1.55HisPro: 1.55 ± 0.043	0.643HisGln: 0.643 ± 0.026	1.551HisArg: 1.551 ± 0.042	0.961HisSer: 0.961 ± 0.033	0.948HisThr: 0.948 ± 0.03	1.543HisVal: 1.543 ± 0.036	0.392HisTrp: 0.392 ± 0.021	0.831HisTyr: 0.831 ± 0.035	0.0HisXaa: 0.0 ± 0.0
Ile	5.441IleAla: 5.441 ± 0.085	0.368IleCys: 0.368 ± 0.019	2.872IleAsp: 2.872 ± 0.06	2.99IleGlu: 2.99 ± 0.059	1.144IlePhe: 1.144 ± 0.042	3.957IleGly: 3.957 ± 0.069	0.884IleHis: 0.884 ± 0.032	1.521IleIle: 1.521 ± 0.043	1.583IleLys: 1.583 ± 0.045	4.248IleLeu: 4.248 ± 0.07	0.812IleMet: 0.812 ± 0.033	1.294IleAsn: 1.294 ± 0.041	2.193IlePro: 2.193 ± 0.047	1.394IleGln: 1.394 ± 0.037	3.02IleArg: 3.02 ± 0.053	2.096IleSer: 2.096 ± 0.055	2.177IleThr: 2.177 ± 0.067	3.205IleVal: 3.205 ± 0.067	0.46IleTrp: 0.46 ± 0.024	1.024IleTyr: 1.024 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.911LysAla: 3.911 ± 0.087	0.231LysCys: 0.231 ± 0.018	1.7LysAsp: 1.7 ± 0.049	1.733LysGlu: 1.733 ± 0.054	0.868LysPhe: 0.868 ± 0.036	2.501LysGly: 2.501 ± 0.056	0.716LysHis: 0.716 ± 0.029	1.417LysIle: 1.417 ± 0.045	1.286LysLys: 1.286 ± 0.053	3.529LysLeu: 3.529 ± 0.072	0.812LysMet: 0.812 ± 0.031	0.887LysAsn: 0.887 ± 0.035	2.046LysPro: 2.046 ± 0.062	1.228LysGln: 1.228 ± 0.036	2.408LysArg: 2.408 ± 0.051	1.576LysSer: 1.576 ± 0.039	1.751LysThr: 1.751 ± 0.05	2.6LysVal: 2.6 ± 0.066	0.372LysTrp: 0.372 ± 0.023	0.76LysTyr: 0.76 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	17.759LeuAla: 17.759 ± 0.212	0.9LeuCys: 0.9 ± 0.036	7.105LeuAsp: 7.105 ± 0.09	5.657LeuGlu: 5.657 ± 0.073	3.929LeuPhe: 3.929 ± 0.078	9.079LeuGly: 9.079 ± 0.111	2.323LeuHis: 2.323 ± 0.06	4.442LeuIle: 4.442 ± 0.074	3.732LeuLys: 3.732 ± 0.068	11.602LeuLeu: 11.602 ± 0.186	2.282LeuMet: 2.282 ± 0.055	2.9LeuAsn: 2.9 ± 0.061	6.154LeuPro: 6.154 ± 0.088	2.952LeuGln: 2.952 ± 0.061	7.667LeuArg: 7.667 ± 0.104	5.658LeuSer: 5.658 ± 0.085	5.372LeuThr: 5.372 ± 0.086	8.172LeuVal: 8.172 ± 0.103	1.206LeuTrp: 1.206 ± 0.037	2.495LeuTyr: 2.495 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	3.267MetAla: 3.267 ± 0.066	0.162MetCys: 0.162 ± 0.015	1.243MetAsp: 1.243 ± 0.039	1.214MetGlu: 1.214 ± 0.038	0.672MetPhe: 0.672 ± 0.028	1.647MetGly: 1.647 ± 0.046	0.572MetHis: 0.572 ± 0.025	0.928MetIle: 0.928 ± 0.034	1.008MetLys: 1.008 ± 0.032	2.534MetLeu: 2.534 ± 0.063	0.57MetMet: 0.57 ± 0.035	0.818MetAsn: 0.818 ± 0.036	1.427MetPro: 1.427 ± 0.043	0.918MetGln: 0.918 ± 0.033	1.77MetArg: 1.77 ± 0.04	1.426MetSer: 1.426 ± 0.039	1.509MetThr: 1.509 ± 0.042	1.674MetVal: 1.674 ± 0.046	0.2MetTrp: 0.2 ± 0.015	0.408MetTyr: 0.408 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.87AsnAla: 2.87 ± 0.067	0.322AsnCys: 0.322 ± 0.017	1.417AsnAsp: 1.417 ± 0.062	1.223AsnGlu: 1.223 ± 0.036	0.856AsnPhe: 0.856 ± 0.03	2.232AsnGly: 2.232 ± 0.059	0.586AsnHis: 0.586 ± 0.023	1.202AsnIle: 1.202 ± 0.042	0.803AsnLys: 0.803 ± 0.034	3.026AsnLeu: 3.026 ± 0.059	0.599AsnMet: 0.599 ± 0.028	0.718AsnAsn: 0.718 ± 0.035	1.919AsnPro: 1.919 ± 0.048	0.896AsnGln: 0.896 ± 0.033	1.941AsnArg: 1.941 ± 0.047	1.141AsnSer: 1.141 ± 0.041	1.191AsnThr: 1.191 ± 0.038	1.964AsnVal: 1.964 ± 0.046	0.407AsnTrp: 0.407 ± 0.021	0.718AsnTyr: 0.718 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	7.631ProAla: 7.631 ± 0.124	0.438ProCys: 0.438 ± 0.024	3.878ProAsp: 3.878 ± 0.075	3.893ProGlu: 3.893 ± 0.072	1.778ProPhe: 1.778 ± 0.043	5.015ProGly: 5.015 ± 0.088	1.022ProHis: 1.022 ± 0.034	1.93ProIle: 1.93 ± 0.047	1.291ProLys: 1.291 ± 0.039	4.657ProLeu: 4.657 ± 0.072	1.283ProMet: 1.283 ± 0.042	1.228ProAsn: 1.228 ± 0.038	2.366ProPro: 2.366 ± 0.067	1.184ProGln: 1.184 ± 0.035	2.787ProArg: 2.787 ± 0.057	2.276ProSer: 2.276 ± 0.057	2.082ProThr: 2.082 ± 0.05	4.537ProVal: 4.537 ± 0.073	0.751ProTrp: 0.751 ± 0.028	1.402ProTyr: 1.402 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	5.225GlnAla: 5.225 ± 0.085	0.298GlnCys: 0.298 ± 0.02	1.756GlnAsp: 1.756 ± 0.042	1.723GlnGlu: 1.723 ± 0.044	1.075GlnPhe: 1.075 ± 0.036	2.679GlnGly: 2.679 ± 0.057	0.749GlnHis: 0.749 ± 0.029	1.383GlnIle: 1.383 ± 0.042	0.967GlnLys: 0.967 ± 0.035	3.405GlnLeu: 3.405 ± 0.062	0.83GlnMet: 0.83 ± 0.031	0.746GlnAsn: 0.746 ± 0.029	1.898GlnPro: 1.898 ± 0.049	1.141GlnGln: 1.141 ± 0.039	2.519GlnArg: 2.519 ± 0.056	1.528GlnSer: 1.528 ± 0.047	1.512GlnThr: 1.512 ± 0.04	2.761GlnVal: 2.761 ± 0.047	0.37GlnTrp: 0.37 ± 0.018	0.764GlnTyr: 0.764 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	8.416ArgAla: 8.416 ± 0.127	0.586ArgCys: 0.586 ± 0.026	3.959ArgAsp: 3.959 ± 0.069	4.298ArgGlu: 4.298 ± 0.088	2.788ArgPhe: 2.788 ± 0.057	4.588ArgGly: 4.588 ± 0.072	2.228ArgHis: 2.228 ± 0.058	3.671ArgIle: 3.671 ± 0.065	2.145ArgLys: 2.145 ± 0.049	9.784ArgLeu: 9.784 ± 0.144	1.879ArgMet: 1.879 ± 0.035	1.891ArgAsn: 1.891 ± 0.049	3.849ArgPro: 3.849 ± 0.076	3.079ArgGln: 3.079 ± 0.061	6.135ArgArg: 6.135 ± 0.102	2.919ArgSer: 2.919 ± 0.06	2.906ArgThr: 2.906 ± 0.058	5.284ArgVal: 5.284 ± 0.082	1.04ArgTrp: 1.04 ± 0.034	2.197ArgTyr: 2.197 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	5.408SerAla: 5.408 ± 0.083	0.507SerCys: 0.507 ± 0.026	2.471SerAsp: 2.471 ± 0.068	2.486SerGlu: 2.486 ± 0.064	1.752SerPhe: 1.752 ± 0.044	4.801SerGly: 4.801 ± 0.09	1.253SerHis: 1.253 ± 0.041	1.89SerIle: 1.89 ± 0.052	1.391SerLys: 1.391 ± 0.04	5.61SerLeu: 5.61 ± 0.094	1.066SerMet: 1.066 ± 0.034	1.214SerAsn: 1.214 ± 0.055	2.325SerPro: 2.325 ± 0.056	1.679SerGln: 1.679 ± 0.044	3.392SerArg: 3.392 ± 0.068	2.299SerSer: 2.299 ± 0.069	2.185SerThr: 2.185 ± 0.062	3.594SerVal: 3.594 ± 0.077	0.637SerTrp: 0.637 ± 0.03	1.234SerTyr: 1.234 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.387ThrAla: 5.387 ± 0.077	0.465ThrCys: 0.465 ± 0.025	2.601ThrAsp: 2.601 ± 0.059	2.446ThrGlu: 2.446 ± 0.051	1.472ThrPhe: 1.472 ± 0.044	4.697ThrGly: 4.697 ± 0.096	0.862ThrHis: 0.862 ± 0.031	1.833ThrIle: 1.833 ± 0.066	1.091ThrLys: 1.091 ± 0.04	5.942ThrLeu: 5.942 ± 0.093	1.006ThrMet: 1.006 ± 0.038	0.988ThrAsn: 0.988 ± 0.034	3.058ThrPro: 3.058 ± 0.061	1.288ThrGln: 1.288 ± 0.039	3.057ThrArg: 3.057 ± 0.058	2.128ThrSer: 2.128 ± 0.074	2.338ThrThr: 2.338 ± 0.068	4.204ThrVal: 4.204 ± 0.144	0.731ThrTrp: 0.731 ± 0.027	1.18ThrTyr: 1.18 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	9.955ValAla: 9.955 ± 0.121	0.73ValCys: 0.73 ± 0.027	4.485ValAsp: 4.485 ± 0.072	4.516ValGlu: 4.516 ± 0.068	2.52ValPhe: 2.52 ± 0.052	5.694ValGly: 5.694 ± 0.097	1.537ValHis: 1.537 ± 0.042	3.193ValIle: 3.193 ± 0.062	2.501ValLys: 2.501 ± 0.072	8.095ValLeu: 8.095 ± 0.105	1.86ValMet: 1.86 ± 0.047	2.147ValAsn: 2.147 ± 0.06	3.643ValPro: 3.643 ± 0.064	2.214ValGln: 2.214 ± 0.052	5.213ValArg: 5.213 ± 0.077	4.044ValSer: 4.044 ± 0.087	3.952ValThr: 3.952 ± 0.129	6.186ValVal: 6.186 ± 0.105	1.009ValTrp: 1.009 ± 0.034	1.889ValTyr: 1.889 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	1.238TrpAla: 1.238 ± 0.04	0.168TrpCys: 0.168 ± 0.013	0.625TrpAsp: 0.625 ± 0.028	0.543TrpGlu: 0.543 ± 0.024	0.544TrpPhe: 0.544 ± 0.025	0.819TrpGly: 0.819 ± 0.029	0.429TrpHis: 0.429 ± 0.022	0.546TrpIle: 0.546 ± 0.024	0.433TrpLys: 0.433 ± 0.022	2.451TrpLeu: 2.451 ± 0.059	0.306TrpMet: 0.306 ± 0.019	0.427TrpAsn: 0.427 ± 0.021	0.72TrpPro: 0.72 ± 0.024	0.835TrpGln: 0.835 ± 0.031	1.364TrpArg: 1.364 ± 0.043	0.699TrpSer: 0.699 ± 0.03	0.57TrpThr: 0.57 ± 0.028	0.857TrpVal: 0.857 ± 0.027	0.292TrpTrp: 0.292 ± 0.02	0.326TrpTyr: 0.326 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.979TyrAla: 2.979 ± 0.057	0.316TyrCys: 0.316 ± 0.017	1.609TyrAsp: 1.609 ± 0.053	1.275TyrGlu: 1.275 ± 0.039	1.037TyrPhe: 1.037 ± 0.033	2.33TyrGly: 2.33 ± 0.047	0.573TyrHis: 0.573 ± 0.027	0.886TyrIle: 0.886 ± 0.034	0.736TyrLys: 0.736 ± 0.028	2.973TyrLeu: 2.973 ± 0.056	0.527TyrMet: 0.527 ± 0.024	0.674TyrAsn: 0.674 ± 0.03	1.296TyrPro: 1.296 ± 0.037	0.989TyrGln: 0.989 ± 0.036	2.248TyrArg: 2.248 ± 0.053	1.264TyrSer: 1.264 ± 0.035	1.282TyrThr: 1.282 ± 0.046	1.845TyrVal: 1.845 ± 0.049	0.38TyrTrp: 0.38 ± 0.021	0.725TyrTyr: 0.725 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2975 proteins (945077 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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