Amino acid dipepetide frequency for Marinobacter persicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.601AlaAla: 9.601 ± 0.128	1.037AlaCys: 1.037 ± 0.033	5.835AlaAsp: 5.835 ± 0.102	6.996AlaGlu: 6.996 ± 0.095	3.542AlaPhe: 3.542 ± 0.073	8.673AlaGly: 8.673 ± 0.14	1.84AlaHis: 1.84 ± 0.044	5.418AlaIle: 5.418 ± 0.083	3.149AlaLys: 3.149 ± 0.071	11.462AlaLeu: 11.462 ± 0.147	2.923AlaMet: 2.923 ± 0.056	3.07AlaAsn: 3.07 ± 0.068	3.722AlaPro: 3.722 ± 0.071	3.4AlaGln: 3.4 ± 0.068	6.88AlaArg: 6.88 ± 0.093	5.591AlaSer: 5.591 ± 0.078	4.774AlaThr: 4.774 ± 0.08	6.832AlaVal: 6.832 ± 0.096	1.338AlaTrp: 1.338 ± 0.039	2.107AlaTyr: 2.107 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.753CysAla: 0.753 ± 0.028	0.128CysCys: 0.128 ± 0.012	0.515CysAsp: 0.515 ± 0.023	0.571CysGlu: 0.571 ± 0.023	0.322CysPhe: 0.322 ± 0.018	0.833CysGly: 0.833 ± 0.031	0.33CysHis: 0.33 ± 0.024	0.403CysIle: 0.403 ± 0.018	0.298CysLys: 0.298 ± 0.02	0.938CysLeu: 0.938 ± 0.028	0.193CysMet: 0.193 ± 0.013	0.25CysAsn: 0.25 ± 0.017	0.52CysPro: 0.52 ± 0.024	0.435CysGln: 0.435 ± 0.025	0.67CysArg: 0.67 ± 0.029	0.494CysSer: 0.494 ± 0.024	0.392CysThr: 0.392 ± 0.022	0.584CysVal: 0.584 ± 0.025	0.136CysTrp: 0.136 ± 0.012	0.252CysTyr: 0.252 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.025AspAla: 5.025 ± 0.09	0.492AspCys: 0.492 ± 0.023	3.588AspAsp: 3.588 ± 0.088	4.418AspGlu: 4.418 ± 0.083	2.175AspPhe: 2.175 ± 0.046	4.464AspGly: 4.464 ± 0.102	1.333AspHis: 1.333 ± 0.036	3.45AspIle: 3.45 ± 0.061	2.213AspLys: 2.213 ± 0.052	5.798AspLeu: 5.798 ± 0.09	1.573AspMet: 1.573 ± 0.043	2.124AspAsn: 2.124 ± 0.07	2.706AspPro: 2.706 ± 0.058	2.521AspGln: 2.521 ± 0.053	3.629AspArg: 3.629 ± 0.065	3.087AspSer: 3.087 ± 0.068	3.113AspThr: 3.113 ± 0.111	4.027AspVal: 4.027 ± 0.074	1.008AspTrp: 1.008 ± 0.031	1.955AspTyr: 1.955 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	6.998GluAla: 6.998 ± 0.105	0.481GluCys: 0.481 ± 0.021	3.672GluAsp: 3.672 ± 0.063	4.553GluGlu: 4.553 ± 0.094	2.321GluPhe: 2.321 ± 0.058	4.664GluGly: 4.664 ± 0.071	1.732GluHis: 1.732 ± 0.045	3.366GluIle: 3.366 ± 0.061	3.229GluLys: 3.229 ± 0.066	7.466GluLeu: 7.466 ± 0.099	1.637GluMet: 1.637 ± 0.046	2.42GluAsn: 2.42 ± 0.058	3.231GluPro: 3.231 ± 0.089	4.25GluGln: 4.25 ± 0.076	4.912GluArg: 4.912 ± 0.094	3.509GluSer: 3.509 ± 0.064	3.688GluThr: 3.688 ± 0.064	4.589GluVal: 4.589 ± 0.085	0.776GluTrp: 0.776 ± 0.031	1.548GluTyr: 1.548 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.337PheAla: 3.337 ± 0.066	0.403PheCys: 0.403 ± 0.022	2.495PheAsp: 2.495 ± 0.054	2.413PheGlu: 2.413 ± 0.058	1.508PhePhe: 1.508 ± 0.047	3.153PheGly: 3.153 ± 0.065	0.815PheHis: 0.815 ± 0.032	1.873PheIle: 1.873 ± 0.042	1.127PheLys: 1.127 ± 0.033	3.526PheLeu: 3.526 ± 0.067	0.879PheMet: 0.879 ± 0.03	1.34PheAsn: 1.34 ± 0.039	1.518PhePro: 1.518 ± 0.043	1.228PheGln: 1.228 ± 0.036	2.398PheArg: 2.398 ± 0.05	2.598PheSer: 2.598 ± 0.057	1.993PheThr: 1.993 ± 0.051	2.646PheVal: 2.646 ± 0.06	0.546PheTrp: 0.546 ± 0.027	1.073PheTyr: 1.073 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	6.534GlyAla: 6.534 ± 0.123	0.838GlyCys: 0.838 ± 0.035	4.37GlyAsp: 4.37 ± 0.112	5.381GlyGlu: 5.381 ± 0.075	3.388GlyPhe: 3.388 ± 0.06	5.79GlyGly: 5.79 ± 0.132	1.907GlyHis: 1.907 ± 0.05	4.509GlyIle: 4.509 ± 0.075	3.514GlyLys: 3.514 ± 0.073	8.251GlyLeu: 8.251 ± 0.099	2.274GlyMet: 2.274 ± 0.054	2.593GlyAsn: 2.593 ± 0.137	2.611GlyPro: 2.611 ± 0.061	3.482GlyGln: 3.482 ± 0.06	4.755GlyArg: 4.755 ± 0.085	4.303GlySer: 4.303 ± 0.102	3.913GlyThr: 3.913 ± 0.08	5.75GlyVal: 5.75 ± 0.083	1.216GlyTrp: 1.216 ± 0.038	2.421GlyTyr: 2.421 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.843HisAla: 1.843 ± 0.047	0.294HisCys: 0.294 ± 0.017	1.231HisAsp: 1.231 ± 0.037	1.396HisGlu: 1.396 ± 0.042	0.957HisPhe: 0.957 ± 0.034	1.803HisGly: 1.803 ± 0.048	0.737HisHis: 0.737 ± 0.029	1.133HisIle: 1.133 ± 0.033	0.783HisLys: 0.783 ± 0.028	2.323HisLeu: 2.323 ± 0.048	0.522HisMet: 0.522 ± 0.025	0.757HisAsn: 0.757 ± 0.031	1.425HisPro: 1.425 ± 0.045	1.083HisGln: 1.083 ± 0.039	1.578HisArg: 1.578 ± 0.048	1.216HisSer: 1.216 ± 0.037	1.121HisThr: 1.121 ± 0.039	1.229HisVal: 1.229 ± 0.038	0.425HisTrp: 0.425 ± 0.023	0.742HisTyr: 0.742 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.489IleAla: 5.489 ± 0.079	0.494IleCys: 0.494 ± 0.022	3.338IleAsp: 3.338 ± 0.064	3.77IleGlu: 3.77 ± 0.069	1.579IlePhe: 1.579 ± 0.048	4.25IleGly: 4.25 ± 0.087	1.132IleHis: 1.132 ± 0.042	2.567IleIle: 2.567 ± 0.062	1.843IleLys: 1.843 ± 0.053	4.597IleLeu: 4.597 ± 0.081	1.138IleMet: 1.138 ± 0.037	2.016IleAsn: 2.016 ± 0.055	2.414IlePro: 2.414 ± 0.055	1.795IleGln: 1.795 ± 0.047	3.585IleArg: 3.585 ± 0.064	3.117IleSer: 3.117 ± 0.065	2.966IleThr: 2.966 ± 0.054	3.479IleVal: 3.479 ± 0.065	0.504IleTrp: 0.504 ± 0.024	1.168IleTyr: 1.168 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	4.009LysAla: 4.009 ± 0.074	0.218LysCys: 0.218 ± 0.017	2.167LysAsp: 2.167 ± 0.065	2.432LysGlu: 2.432 ± 0.062	0.96LysPhe: 0.96 ± 0.034	2.746LysGly: 2.746 ± 0.059	0.921LysHis: 0.921 ± 0.033	1.751LysIle: 1.751 ± 0.045	1.893LysLys: 1.893 ± 0.061	3.789LysLeu: 3.789 ± 0.063	0.887LysMet: 0.887 ± 0.029	1.241LysAsn: 1.241 ± 0.04	2.135LysPro: 2.135 ± 0.054	1.775LysGln: 1.775 ± 0.046	2.468LysArg: 2.468 ± 0.047	2.015LysSer: 2.015 ± 0.052	2.152LysThr: 2.152 ± 0.055	2.794LysVal: 2.794 ± 0.064	0.363LysTrp: 0.363 ± 0.021	0.864LysTyr: 0.864 ± 0.034	0.0LysXaa: 0.0 ± 0.0
Leu	12.569LeuAla: 12.569 ± 0.139	0.91LeuCys: 0.91 ± 0.032	6.4LeuAsp: 6.4 ± 0.104	7.255LeuGlu: 7.255 ± 0.105	3.887LeuPhe: 3.887 ± 0.068	7.878LeuGly: 7.878 ± 0.105	2.091LeuHis: 2.091 ± 0.046	5.216LeuIle: 5.216 ± 0.092	4.324LeuLys: 4.324 ± 0.074	10.878LeuLeu: 10.878 ± 0.151	2.698LeuMet: 2.698 ± 0.053	3.498LeuAsn: 3.498 ± 0.065	5.493LeuPro: 5.493 ± 0.091	4.015LeuGln: 4.015 ± 0.067	6.355LeuArg: 6.355 ± 0.085	6.584LeuSer: 6.584 ± 0.091	5.65LeuThr: 5.65 ± 0.09	7.833LeuVal: 7.833 ± 0.107	1.249LeuTrp: 1.249 ± 0.041	2.256LeuTyr: 2.256 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	3.111MetAla: 3.111 ± 0.059	0.15MetCys: 0.15 ± 0.014	1.444MetAsp: 1.444 ± 0.042	1.53MetGlu: 1.53 ± 0.045	0.693MetPhe: 0.693 ± 0.03	1.827MetGly: 1.827 ± 0.053	0.5MetHis: 0.5 ± 0.024	1.298MetIle: 1.298 ± 0.038	1.156MetLys: 1.156 ± 0.035	2.568MetLeu: 2.568 ± 0.057	0.716MetMet: 0.716 ± 0.028	0.94MetAsn: 0.94 ± 0.031	1.43MetPro: 1.43 ± 0.04	1.02MetGln: 1.02 ± 0.032	1.417MetArg: 1.417 ± 0.038	1.642MetSer: 1.642 ± 0.045	1.649MetThr: 1.649 ± 0.049	1.868MetVal: 1.868 ± 0.044	0.158MetTrp: 0.158 ± 0.014	0.44MetTyr: 0.44 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.045AsnAla: 3.045 ± 0.069	0.273AsnCys: 0.273 ± 0.019	1.828AsnAsp: 1.828 ± 0.077	1.991AsnGlu: 1.991 ± 0.051	1.117AsnPhe: 1.117 ± 0.036	2.727AsnGly: 2.727 ± 0.07	0.795AsnHis: 0.795 ± 0.029	1.634AsnIle: 1.634 ± 0.045	1.148AsnLys: 1.148 ± 0.041	3.499AsnLeu: 3.499 ± 0.066	0.77AsnMet: 0.77 ± 0.028	1.195AsnAsn: 1.195 ± 0.039	2.106AsnPro: 2.106 ± 0.046	1.431AsnGln: 1.431 ± 0.043	2.437AsnArg: 2.437 ± 0.049	1.669AsnSer: 1.669 ± 0.055	1.753AsnThr: 1.753 ± 0.049	2.122AsnVal: 2.122 ± 0.062	0.499AsnTrp: 0.499 ± 0.025	0.894AsnTyr: 0.894 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	4.79ProAla: 4.79 ± 0.08	0.323ProCys: 0.323 ± 0.018	3.566ProAsp: 3.566 ± 0.064	4.925ProGlu: 4.925 ± 0.097	1.711ProPhe: 1.711 ± 0.04	4.086ProGly: 4.086 ± 0.072	0.924ProHis: 0.924 ± 0.035	1.852ProIle: 1.852 ± 0.05	1.523ProLys: 1.523 ± 0.04	4.535ProLeu: 4.535 ± 0.079	1.2ProMet: 1.2 ± 0.037	1.276ProAsn: 1.276 ± 0.036	1.861ProPro: 1.861 ± 0.05	1.551ProGln: 1.551 ± 0.044	2.218ProArg: 2.218 ± 0.043	2.323ProSer: 2.323 ± 0.054	1.964ProThr: 1.964 ± 0.042	4.306ProVal: 4.306 ± 0.083	0.738ProTrp: 0.738 ± 0.031	1.063ProTyr: 1.063 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	4.976GlnAla: 4.976 ± 0.085	0.344GlnCys: 0.344 ± 0.019	1.89GlnAsp: 1.89 ± 0.046	2.493GlnGlu: 2.493 ± 0.059	1.377GlnPhe: 1.377 ± 0.038	3.022GlnGly: 3.022 ± 0.06	0.989GlnHis: 0.989 ± 0.036	1.883GlnIle: 1.883 ± 0.044	1.619GlnLys: 1.619 ± 0.046	4.697GlnLeu: 4.697 ± 0.075	1.047GlnMet: 1.047 ± 0.032	1.273GlnAsn: 1.273 ± 0.038	2.179GlnPro: 2.179 ± 0.049	2.499GlnGln: 2.499 ± 0.062	2.896GlnArg: 2.896 ± 0.059	2.26GlnSer: 2.26 ± 0.049	2.113GlnThr: 2.113 ± 0.045	3.205GlnVal: 3.205 ± 0.06	0.714GlnTrp: 0.714 ± 0.03	0.989GlnTyr: 0.989 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	5.644ArgAla: 5.644 ± 0.079	0.585ArgCys: 0.585 ± 0.024	3.603ArgAsp: 3.603 ± 0.073	4.901ArgGlu: 4.901 ± 0.084	2.797ArgPhe: 2.797 ± 0.068	3.804ArgGly: 3.804 ± 0.067	1.727ArgHis: 1.727 ± 0.042	3.694ArgIle: 3.694 ± 0.072	2.842ArgLys: 2.842 ± 0.062	7.468ArgLeu: 7.468 ± 0.105	1.7ArgMet: 1.7 ± 0.039	2.204ArgAsn: 2.204 ± 0.053	2.644ArgPro: 2.644 ± 0.052	3.492ArgGln: 3.492 ± 0.08	4.408ArgArg: 4.408 ± 0.089	3.319ArgSer: 3.319 ± 0.063	2.784ArgThr: 2.784 ± 0.063	4.522ArgVal: 4.522 ± 0.065	1.028ArgTrp: 1.028 ± 0.035	2.072ArgTyr: 2.072 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	5.451SerAla: 5.451 ± 0.095	0.428SerCys: 0.428 ± 0.024	3.23SerAsp: 3.23 ± 0.063	3.865SerGlu: 3.865 ± 0.069	2.163SerPhe: 2.163 ± 0.056	5.221SerGly: 5.221 ± 0.097	1.32SerHis: 1.32 ± 0.037	2.741SerIle: 2.741 ± 0.059	1.916SerLys: 1.916 ± 0.047	6.202SerLeu: 6.202 ± 0.094	1.466SerMet: 1.466 ± 0.04	1.646SerAsn: 1.646 ± 0.043	2.557SerPro: 2.557 ± 0.05	2.229SerGln: 2.229 ± 0.055	3.787SerArg: 3.787 ± 0.071	3.284SerSer: 3.284 ± 0.071	2.643SerThr: 2.643 ± 0.06	4.261SerVal: 4.261 ± 0.077	0.752SerTrp: 0.752 ± 0.03	1.307SerTyr: 1.307 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	4.687ThrAla: 4.687 ± 0.077	0.473ThrCys: 0.473 ± 0.023	3.172ThrAsp: 3.172 ± 0.065	3.245ThrGlu: 3.245 ± 0.059	1.819ThrPhe: 1.819 ± 0.044	5.174ThrGly: 5.174 ± 0.123	1.028ThrHis: 1.028 ± 0.033	2.534ThrIle: 2.534 ± 0.052	1.289ThrLys: 1.289 ± 0.041	6.519ThrLeu: 6.519 ± 0.119	1.037ThrMet: 1.037 ± 0.034	1.425ThrAsn: 1.425 ± 0.038	2.861ThrPro: 2.861 ± 0.049	1.486ThrGln: 1.486 ± 0.036	3.357ThrArg: 3.357 ± 0.067	2.74ThrSer: 2.74 ± 0.054	2.625ThrThr: 2.625 ± 0.056	4.07ThrVal: 4.07 ± 0.072	0.604ThrTrp: 0.604 ± 0.025	1.173ThrTyr: 1.173 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	7.263ValAla: 7.263 ± 0.095	0.714ValCys: 0.714 ± 0.029	4.315ValAsp: 4.315 ± 0.062	4.824ValGlu: 4.824 ± 0.071	2.919ValPhe: 2.919 ± 0.058	4.872ValGly: 4.872 ± 0.088	1.477ValHis: 1.477 ± 0.043	4.213ValIle: 4.213 ± 0.074	2.497ValLys: 2.497 ± 0.06	7.453ValLeu: 7.453 ± 0.095	2.016ValMet: 2.016 ± 0.049	2.471ValAsn: 2.471 ± 0.062	3.365ValPro: 3.365 ± 0.068	2.392ValGln: 2.392 ± 0.05	4.483ValArg: 4.483 ± 0.067	4.563ValSer: 4.563 ± 0.075	4.17ValThr: 4.17 ± 0.07	5.984ValVal: 5.984 ± 0.102	0.859ValTrp: 0.859 ± 0.036	1.706ValTyr: 1.706 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.001TrpAla: 1.001 ± 0.034	0.152TrpCys: 0.152 ± 0.013	0.605TrpAsp: 0.605 ± 0.024	0.635TrpGlu: 0.635 ± 0.028	0.603TrpPhe: 0.603 ± 0.028	0.81TrpGly: 0.81 ± 0.035	0.382TrpHis: 0.382 ± 0.019	0.616TrpIle: 0.616 ± 0.025	0.416TrpLys: 0.416 ± 0.02	2.164TrpLeu: 2.164 ± 0.058	0.354TrpMet: 0.354 ± 0.018	0.386TrpAsn: 0.386 ± 0.021	0.668TrpPro: 0.668 ± 0.031	1.032TrpGln: 1.032 ± 0.037	0.95TrpArg: 0.95 ± 0.034	0.748TrpSer: 0.748 ± 0.031	0.552TrpThr: 0.552 ± 0.023	0.908TrpVal: 0.908 ± 0.033	0.243TrpTrp: 0.243 ± 0.019	0.342TrpTyr: 0.342 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.064TyrAla: 2.064 ± 0.046	0.281TyrCys: 0.281 ± 0.019	1.437TyrAsp: 1.437 ± 0.04	1.448TyrGlu: 1.448 ± 0.04	1.031TyrPhe: 1.031 ± 0.04	1.998TyrGly: 1.998 ± 0.045	0.619TyrHis: 0.619 ± 0.026	1.089TyrIle: 1.089 ± 0.04	0.799TyrLys: 0.799 ± 0.033	2.906TyrLeu: 2.906 ± 0.057	0.527TyrMet: 0.527 ± 0.027	0.809TyrAsn: 0.809 ± 0.029	1.287TyrPro: 1.287 ± 0.041	1.347TyrGln: 1.347 ± 0.041	2.061TyrArg: 2.061 ± 0.044	1.409TyrSer: 1.409 ± 0.034	1.302TyrThr: 1.302 ± 0.039	1.545TyrVal: 1.545 ± 0.039	0.413TyrTrp: 0.413 ± 0.02	0.716TyrTyr: 0.716 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2913 proteins (959929 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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